Holger Jahn

Holger Jahn

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Holger Jahn

Publications by authors named "Holger Jahn"

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MicroRNA Profiling of Alzheimer's Disease Cerebrospinal Fluid.

Methods Mol Biol 2018 ;1750:93-107

Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1007/978-1-4939-7704-8_6DOI Listing
February 2019

Therapeutic Drug Monitoring of Naltrexone and 6β-Naltrexol During Anti-craving Treatment in Alcohol Dependence: Reference Ranges.

Alcohol Alcohol 2019 Jan;54(1):51-55

Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Germany.

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https://academic.oup.com/alcalc/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/alcalc/agy067DOI Listing
January 2019

Serum neurofilament light chain in behavioral variant frontotemporal dementia.

Neurology 2018 10 12;91(15):e1390-e1401. Epub 2018 Sep 12.

From the Department of Neurology (P.S., S.A.-S., E.S., I.U., C.A.F.v.A., J. Kassubek, B.L., P.O., A.C.L., M.O.) and Institute of Epidemiology and Medical Biometry (B.M.), University of Ulm; Department of Psychiatry and Psychotherapy (J.D.-S., H.F., T.G.), Klinikum Rechts der Isar, Technical University of Munich; Department of Nuclear Medicine (H.B.), Leipzig University Hospital; Department of Neurology (A.D.), Ludwig-Maximilians-University, Munich; Department of Neurology (K.F.), Saarland University, Homburg; Department of Psychiatry and Psychotherapy (K.F.), University of Bonn, Germany; Swiss Epilepsy Center (H.-J.H.), Zurich, Switzerland; Department of Psychiatry and Psychotherapy (H.J.), University Medical Center Hamburg-Eppendorf, Hamburg; AMEOS Klinikum (H.J.), Heiligenhafen; Department of Psychiatry and Psychotherapy (J. Kornhuber, J.M.M.), Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen; Department of Psychiatry and Psychotherapy (M.L.), University of Würzburg; Department of Neurology (J.P.), University of Rostock; DZNE (J.P.), Rostock; Department of Neurodegenerative Diseases and Geriatric Psychiatry (A.S.), University Hospital Bonn; DZNE (A.S.), Bonn; Institute of Human Genetics (A.E.V.), University Medical Center Hamburg-Eppendorf, Hamburg; Department of Psychiatry and Psychotherapy (J.W.), University Medical Center Göttingen; DZNE (J.W.), Göttingen, Germany; iBiMED (J.W.), Medical Sciences Department, University of Aveiro, Portugal; Clinic for Cognitive Neurology (M.L.S.), University Clinic Leipzig; and Max Planck Institute for Human Cognitive and Brain Sciences (M.L.S.), Leipzig, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006318DOI Listing
October 2018

Alzheimer's disease: Elevated pigment epithelium-derived factor in the cerebrospinal fluid is mostly of systemic origin.

J Neurol Sci 2017 Apr 17;375:123-128. Epub 2017 Jan 17.

Department of Neurosurgery, Experimental Neurosurgery, Charité - Universitätsmedizin, Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies, Charité - Universitätsmedizin, Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2017.01.051DOI Listing
April 2017

Copeptin - A potential endocrine surrogate marker of CCK-4-induced panic symptoms?

Psychoneuroendocrinology 2017 02 8;76:14-18. Epub 2016 Nov 8.

University Hospital Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.psyneuen.2016.11.006DOI Listing
February 2017

Amyloid-β Precursor Protein Modulates the Sorting of Testican-1 and Contributes to Its Accumulation in Brain Tissue and Cerebrospinal Fluid from Patients with Alzheimer Disease.

J Neuropathol Exp Neurol 2016 09 2;75(9):903-16. Epub 2016 Aug 2.

From the Institute of Neuropathology (AB-O, JM, BP, MG, DS-F), Department of Psychiatry and Psychotherapy (SA, HJ), University Medical Center Hamburg-Eppendorf, Hamburg, Germany, Center for Biochemistry, Medical Faculty, University of Cologne, Cologne, Germany (UH), Institute of Neuropathology, Bellvitge University Hospital, CIBERNED, Hospitalet de Llobregat, University of Barcelona, Spain (IF), Mosaiques Diagnostics and Therapeutics AG, Hannover, Germany (PZ), and Department of Pharmaceutical Sciences, Natura Research Group, Faculty of Natural Sciences, ICESI University, Cali, Colombia (AB-O).

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https://academic.oup.com/jnen/article-lookup/doi/10.1093/jne
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http://dx.doi.org/10.1093/jnen/nlw065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015660PMC
September 2016

MicroRNA Profiling of CSF Reveals Potential Biomarkers to Detect Alzheimer`s Disease.

PLoS One 2015 20;10(5):e0126423. Epub 2015 May 20.

Department of Psychiatry and Psychotherapy, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126423PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439119PMC
April 2016

Steroid-synthesis inhibition in depression: a good idea?

Authors:
Holger Jahn

Lancet Psychiatry 2016 Feb 23;3(2):92-3. Epub 2015 Dec 23.

Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg 20251, Germany. Electronic address:

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http://dx.doi.org/10.1016/S2215-0366(15)00494-0DOI Listing
February 2016

Nonfluent Variant of Primary Progressive Aphasia With Right Hemisphere Atrophy - A Phenotype of Corticobasal Degeneration?

Mov Disord Clin Pract 2015 Dec 30;2(4):420-421. Epub 2015 Jun 30.

Department of Psychiatry University Medical Center Hamburg-Eppendorf Hamburg Germany.

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http://doi.wiley.com/10.1002/mdc3.12209
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http://dx.doi.org/10.1002/mdc3.12209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6178769PMC
December 2015

Overnight suppression of HPA axis after mineraolocorticoid receptor stimulation: A sleep endocrine study.

Psychiatry Res 2015 May 24;227(1):65-70. Epub 2015 Feb 24.

University Medical Center Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany; Max Planck Institute of Psychiatry, Munich, Germany.

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http://dx.doi.org/10.1016/j.psychres.2015.02.008DOI Listing
May 2015

Subjective cognitive decline is related to CSF biomarkers of AD in patients with MCI.

Neurology 2015 Mar 25;84(12):1261-8. Epub 2015 Feb 25.

From the Department of Psychiatry (S.W., F.J., A. Koppara, L.K., W.M., M.W.), University of Bonn; German Center for Neurodegenerative Diseases (S.W., F.J. A. Koppara, L.K., W.M., M.W.), Bonn; Center for Geriatric Medicine (K.S.), Ortenau Klinikum, Offenburg-Gengenbach; Department of Gerontopsychiatry (L.F.), Central Institute of Mental Health, Mannheim; Department of Psychiatry (A. Kurz), Technical University of Munich; Department of Neurology (S.S.), University of Aachen; Department of Psychiatry and Psychotherapy (S.S., E.R., J.W.), University of Göttingen, Germany; AXA Research Fund & UPMC Chair Sorbonne Universités (H.H.), Université Pierre et Marie Curie, Paris; Institut de la Mémoire et de la Maladie d'Alzheimer (H.H.), Département de Neurologie, Hôpital de la Pitié-Salpétrière, Paris; INSERM U1127 (H.H.), Institut du Cerveau et de la Moelle épinière, Paris, France; Department of Psychiatry (I.H., O.P., F.M.R.), Charité Berlin, Campus Benjamin Franklin, Berlin; Department of Psychiatry (H.J.), University of Hamburg; Department of Psychiatry (C.L.), University of Düsseldorf; Center for Geriatric Medicine and Gerontology (M.H.), University of Freiburg; Department of Psychiatry (H.-J.G.), University of Leipzig; Department of Psychiatry (J.S.), University of Heidelberg; Department of General Medicine (J.P.), University of Frankfurt, Frankfurt am Main; Department of Medical Informatics (O.R.), University of Göttingen, Germany; Brookhaven National Laboratory (F.H.), Upton, New York; and Department of Psychiatry (J.K.), Friedrich-Alexander University Erlangen, Germany. F.J. is currently with the Department of Psychiatry, University of Cologne.

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http://dx.doi.org/10.1212/WNL.0000000000001399DOI Listing
March 2015

Cerebrospinal fluid cortisol and clinical disease progression in MCI and dementia of Alzheimer's type.

Neurobiol Aging 2015 Feb 31;36(2):601-7. Epub 2014 Oct 31.

Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.10.031DOI Listing
February 2015

Investigations on CXCL13 in anti-N-methyl-D-aspartate receptor encephalitis: a potential biomarker of treatment response.

JAMA Neurol 2015 Feb;72(2):180-6

August Pi i Sunyer Biomedical Research Institute (IDIBAPS), Service of Neurology, Hospital Clínic, University of Barcelona, Barcelona, Spain10Department of Neurology, University of Pennsylvania, Philadelphia11Catalan Institution for Research and Advanced.

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http://dx.doi.org/10.1001/jamaneurol.2014.2956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836910PMC
February 2015

A novel computerized algorithm to detect microstructural brainstem pathology in Parkinson's disease using standard 3 Tesla MR imaging.

J Neurol 2014 Oct 26;261(10):1968-75. Epub 2014 Jul 26.

Department of Psychiatry, Memory Clinic, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany,

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http://dx.doi.org/10.1007/s00415-014-7440-6DOI Listing
October 2014

A novel presenilin 1 mutation (Ala275Val) as cause of early-onset familial Alzheimer disease.

Neurosci Lett 2014 Apr 26;566:115-9. Epub 2014 Feb 26.

Department of Psychiatry, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2014.02.034DOI Listing
April 2014

Mirtazapine-induced galactorrhea: a case report.

J Neuropsychiatry Clin Neurosci 2013 ;25(2):E13-4

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http://dx.doi.org/10.1176/appi.neuropsych.12030071DOI Listing
January 2014

Memory loss in Alzheimer's disease.

Authors:
Holger Jahn

Dialogues Clin Neurosci 2013 Dec;15(4):445-54

University Hospital Hamburg-Eppendorf, Dept of Psychiatry and Psychotherapy, Hamburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3898682PMC
December 2013

No effects of antidepressants on negative symptoms in schizophrenia.

J Clin Psychopharmacol 2013 Oct;33(5):686-90

Department of Psychiatry and Psychotherapy, University of Hamburg, Hamburg, Germany.

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http://dx.doi.org/10.1097/JCP.0b013e3182971e68DOI Listing
October 2013

Dimethylarginines, homocysteine metabolism, and cerebrospinal fluid markers for Alzheimer's disease.

J Alzheimers Dis 2012 ;31(4):751-8

Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.3233/JAD-2012-112138DOI Listing
July 2013

Genetic risk factors for depression in Alzheimer`s disease patients.

Curr Alzheimer Res 2013 Jan;10(1):72-81

Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Martinistr. 52, Building W 37, 20246 Hamburg, Germany.

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January 2013

Use of proteomic methods in the analysis of human body fluids in Alzheimer research.

Electrophoresis 2012 Dec;33(24):3617-30

Mosaiques Diagnostics GmbH, Hannover, Germany.

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http://dx.doi.org/10.1002/elps.201200360DOI Listing
December 2012

Differential effects to CCK-4-induced panic by dexamethasone and hydrocortisone.

World J Biol Psychiatry 2012 Oct 23;13(7):526-34. Epub 2011 Nov 23.

University Hospital Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany.

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http://dx.doi.org/10.3109/15622975.2011.604351DOI Listing
October 2012

CCK-4: Psychophysiological conditioning elicits features of spontaneous panic attacks.

J Psychiatr Res 2010 Dec 6;44(16):1148-53. Epub 2010 May 6.

Department of Psychiatry and Psychotherapy, University of Hamburg, Martinistr 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.jpsychires.2010.04.004DOI Listing
December 2010

Influence of exogenous atrial natriuretic peptide on the nocturnal hypothalamic-pituitary-adrenal axis and sleep in healthy men.

Psychoneuroendocrinology 2010 Nov 2;35(10):1438-45. Epub 2010 Jun 2.

University Hospital Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.psyneuen.2010.04.009DOI Listing
November 2010

Augmented stress-induced alcohol drinking and withdrawal in mice lacking functional natriuretic peptide-A receptors.

Alcohol Alcohol 2010 Jan-Feb;45(1):13-6. Epub 2009 Oct 13.

Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, University of Heidelberg, J 5, 68159 Mannheim, Germany.

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http://dx.doi.org/10.1093/alcalc/agp065DOI Listing
March 2010

Association between FDG uptake, CSF biomarkers and cognitive performance in patients with probable Alzheimer's disease.

Eur J Nucl Med Mol Imaging 2009 Jul 14;36(7):1090-100. Epub 2009 Feb 14.

Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00259-009-1063-7DOI Listing
July 2009

Asymmetrical dimethylarginine is increased in plasma and decreased in cerebrospinal fluid of patients with Alzheimer's disease.

Dement Geriatr Cogn Disord 2008 10;26(1):58-64. Epub 2008 Jul 10.

Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1159/000144026DOI Listing
October 2008

The patient with dementia, the caregiver and the doctor: cognition, depression and quality of life from three perspectives.

Int J Geriatr Psychiatry 2008 Jun;23(6):604-10

Department of Psychiatry and Psychotherapy, Centre of Psychosocial Medicine, University Medical Center Hamburg-Eppendorf, Germany.

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http://doi.wiley.com/10.1002/gps.1946
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http://dx.doi.org/10.1002/gps.1946DOI Listing
June 2008

Capillary electrophoresis mass spectrometry as a potential tool to detect lithium-induced nephropathy: Preliminary results.

Prog Neuropsychopharmacol Biol Psychiatry 2008 Apr 23;32(3):673-8. Epub 2007 Nov 23.

University Medical Center Hamburg-Eppendorf, Dept. of Psychiatry, Martinistr. 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.pnpbp.2007.11.015DOI Listing
April 2008

Megestrol attenuates the hormonal response to CCK-4-induced panic attacks.

Depress Anxiety 2006 ;23(3):139-44

Department of Psychiatry and Psychotherapy, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/da.20147DOI Listing
November 2006

Pharmacological treatment of non-Alzheimer dementias.

Curr Opin Psychiatry 2006 Nov;19(6):642-8

Department of Psychiatry and Psychotherapy, University Hospital Hamburg-Eppendorf (UKE), Hamburg, Germany.

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http://dx.doi.org/10.1097/01.yco.0000245755.21621.80DOI Listing
November 2006

Effects of treatment with acamprosate on beta-endorphin plasma concentration in humans with high alcohol preference.

Neurosci Lett 2006 Aug 19;404(1-2):103-6. Epub 2006 Jun 19.

Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health (CIMH), University of Heidelberg, Mannheim, Germany.

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http://dx.doi.org/10.1016/j.neulet.2006.05.015DOI Listing
August 2006

Hypothalamic-pituitary-adrenocortical axis activity: a target of pharmacological anticraving treatment?

Biol Psychiatry 2006 Jul 14;60(1):74-6. Epub 2006 Feb 14.

Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S000632230501460
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http://dx.doi.org/10.1016/j.biopsych.2005.11.023DOI Listing
July 2006

Increasing leptin precedes craving and relapse during pharmacological abstinence maintenance treatment of alcoholism.

J Psychiatr Res 2005 Sep 21;39(5):545-51. Epub 2005 Jan 21.

Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health (CIMH), University of Heidelberg, J5, 68159 Mannheim, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S002239560400165
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http://dx.doi.org/10.1016/j.jpsychires.2004.11.005DOI Listing
September 2005

Pharmacological relapse prevention of alcoholism: clinical predictors of outcome.

Eur Addict Res 2005 ;11(2):83-91

Department of Addictive Behaviour and Addiction Medicine, Central Institute of Mental Health (CIMH), University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000083037DOI Listing
July 2005

Metyrapone as additive treatment in major depression: a double-blind and placebo-controlled trial.

Arch Gen Psychiatry 2004 Dec;61(12):1235-44

Department of Psychiatry and Psychotherapy, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1001/archpsyc.61.12.1235DOI Listing
December 2004

Adjunctive use of reboxetine in schizophrenia.

Eur Psychiatry 2004 Sep;19(6):366-9

University Hospital Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Martini str. 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.eurpsy.2004.06.017DOI Listing
September 2004

Overnight metyrapone and combined dexamethasone/metyrapone tests in post-traumatic stress disorder: preliminary findings.

Eur Neuropsychopharmacol 2004 Aug;14(4):337-9

Department of Psychiatry and Psychotherapy, University Hospital Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.euroneuro.2003.11.002DOI Listing
August 2004

Dimensional structure of the Hamilton Depression Rating Scale in patients with obsessive-compulsive disorder.

Psychiatry Res 2004 Feb;125(2):171-80

University Hospital Hamburg-Eppendorf, Hospital for Psychiatry and Psychotherapy, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1016/j.psychres.2003.11.003DOI Listing
February 2004

Acute effects of megestrol on the hypothalamic-pituitary-adrenal axis.

Cancer Chemother Pharmacol 2003 Dec 16;52(6):482-6. Epub 2003 Sep 16.

Department of Psychiatry and Psychotherapy, University of Hamburg Medical Center, Martinistr. 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1007/s00280-003-0697-6DOI Listing
December 2003

Modulation of sympathetic activity by corticotropin-releasing hormone and atrial natriuretic peptide.

Neuropeptides 2003 Dec;37(6):362-8

Department of Psychiatry and Psychotherapy, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

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http://dx.doi.org/10.1016/j.npep.2003.09.006DOI Listing
December 2003

Sleep endocrine effects of the 11-beta-hydroxysteroiddehydrogenase inhibitor metyrapone.

Sleep 2003 Nov;26(7):823-9

Department of Psychiatry and Psychotherapy, University of Hamburg, Hamburg, Germany.

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http://dx.doi.org/10.1093/sleep/26.7.823DOI Listing
November 2003

Impact of comorbid depressive symptoms on nonverbal memory and visuospatial performance in obsessive-compulsive disorder.

Cogn Neuropsychiatry 2003 Nov;8(4):261-72

University Hospital Hamburg-Eppendorf, Hospital for Psychiatry and Psychotherapy, Clinical Neuropsychology Unit, Hamburg, Germany.

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http://dx.doi.org/10.1080/135468000344000020DOI Listing
November 2003

Mineralocorticoid receptor-mediated inhibition of the hypothalamic-pituitary-adrenal axis in aged humans.

J Gerontol A Biol Sci Med Sci 2003 Oct;58(10):B900-5

Department of Psychiatry and Psychotherapy, University Hospital Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1093/gerona/58.10.b900DOI Listing
October 2003

The mineralocorticoid receptor agonist, fludrocortisone, inhibits pituitary-adrenal activity in humans after pre-treatment with metyrapone.

Life Sci 2003 Aug;73(14):1835-45

Department of Psychiatry and Psychotherapy, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1016/s0024-3205(03)00513-7DOI Listing
August 2003

Natriuretic peptides and panic disorder: therapeutic prospects.

Expert Rev Neurother 2003 May;3(3):381-6

University Hospital Hamburg Eppendorf, Department of Psychiatry and Psychotherapy, Martinistrasse 52, 20246 Hamburg, Germany.

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http://dx.doi.org/10.1586/14737175.3.3.381DOI Listing
May 2003

Alcohol self-administration, craving and HPA-axis activity: an intriguing relationship.

Psychopharmacology (Berl) 2002 Nov 18;164(2):239-40. Epub 2002 Sep 18.

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http://dx.doi.org/10.1007/s00213-002-1255-3DOI Listing
November 2002

Is withdrawal-induced anxiety in alcoholism based on beta-endorphin deficiency?

Psychopharmacology (Berl) 2002 Aug 25;162(4):433-7. Epub 2002 Jun 25.

Department of Psychiatry, University Hospital Hamburg-Eppendorf, Martinistrasse 52, 20251 Hamburg, Germany.

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http://dx.doi.org/10.1007/s00213-002-1118-yDOI Listing
August 2002

Executive functioning in obsessive-compulsive disorder, unipolar depression, and schizophrenia.

Arch Clin Neuropsychol 2002 Jul;17(5):477-83

Clinic for Psychiatry and Psychotherapy, University Clinic Hamburg-Eppendorf, Martinistrasse 52, D-20246 Hamburg, Germany.

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July 2002

Prolactin but not ACTH increases during sodium lactate-induced panic attacks.

Psychiatry Res 2002 Mar;109(2):201-5

University Hospital Hamburg-Eppendorf, Department of Psychiatry and Psychotherapy, Martinistrasse 52, 20246, Germany.

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http://dx.doi.org/10.1016/s0165-1781(02)00014-8DOI Listing
March 2002