Holger Gerhardt

Holger Gerhardt

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Holger Gerhardt

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Opposite Macrophage Polarization in Different Subsets of Ovarian Cancer: Observation from a Pilot Study.

Cells 2020 Jan 27;9(2). Epub 2020 Jan 27.

ImmunOvar Research Group, Laboratory of Tumor Immunology and Immunotherapy, Department of Oncology, KU Leuven, 3000 Leuven, Belgium.

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http://dx.doi.org/10.3390/cells9020305DOI Listing
January 2020

ATTRACT.

Circ Res 2019 Jul 18;125(3):262-264. Epub 2019 Jul 18.

From the Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany (P.B.G., H.G.).

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http://dx.doi.org/10.1161/CIRCRESAHA.119.315198DOI Listing
July 2019

Imaging Glioma Progression by Intravital Microscopy.

Methods Mol Biol 2019 ;1862:227-243

VIB-KU Leuven Center for Cancer Biology (CCB), Leuven, Belgium.

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http://link.springer.com/10.1007/978-1-4939-8769-6_16
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http://dx.doi.org/10.1007/978-1-4939-8769-6_16DOI Listing
June 2019

Myeloid Derived Suppressor Cells: Key Drivers of Immunosuppression in Ovarian Cancer.

Front Immunol 2019 4;10:1273. Epub 2019 Jun 4.

ImmunOvar Research Group, Laboratory of Tumor Immunology and Immunotherapy, Department of Oncology, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.3389/fimmu.2019.01273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558014PMC
June 2019

Imaging of Endothelial Cell Dynamic Behavior in Zebrafish.

Methods Mol Biol 2018 ;1846:181-195

Integrative Vascular Biology Laboratory, Max-Delbrück Center for Molecular Medicine (MDC), Berlin, Germany.

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http://dx.doi.org/10.1007/978-1-4939-8712-2_12DOI Listing
May 2019

Endothelial Calcineurin Signaling Restrains Metastatic Outgrowth by Regulating Bmp2.

Cell Rep 2019 01;26(5):1227-1241.e6

Department of Oncology, University of Lausanne, Lausanne 1011, Switzerland; Ludwig Institute for Cancer Research Lausanne, Lausanne, Switzerland; Division of Experimental Pathology, CHUV, Epalinges 1066, Switzerland; Swiss Institute for Cancer Research, École Polytechnique Fédérale de Lausanne, Lausanne 1015, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247193002
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http://dx.doi.org/10.1016/j.celrep.2019.01.016DOI Listing
January 2019

NanoSIMS imaging reveals unexpected heterogeneity in nutrient uptake by brown adipocytes.

Biochem Biophys Res Commun 2018 10 15;504(4):899-902. Epub 2018 Sep 15.

Departments of Medicine, University of California, Los Angeles, CA, 90095, USA; School of Molecular Sciences and Centre for Microscopy, Characterisation and Analysis, University of Western Australia, Perth, 6009, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X183196
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http://dx.doi.org/10.1016/j.bbrc.2018.09.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6476570PMC
October 2018

Mutations in Disordered Regions Can Cause Disease by Creating Dileucine Motifs.

Cell 2018 09 6;175(1):239-253.e17. Epub 2018 Sep 6.

Proteome Dynamics, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Str. 10, 13125 Berlin, Germany; Charité-Universitätsmedizin Berlin, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.08.019DOI Listing
September 2018

Hold Me, but Not Too Tight-Endothelial Cell-Cell Junctions in Angiogenesis.

Cold Spring Harb Perspect Biol 2018 08 1;10(8). Epub 2018 Aug 1.

Integrative Vascular Biology Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125, Berlin, Germany.

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http://dx.doi.org/10.1101/cshperspect.a029223DOI Listing
August 2018

PolNet: A Tool to Quantify Network-Level Cell Polarity and Blood Flow in Vascular Remodeling.

Biophys J 2018 05;114(9):2052-2058

Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2018.03.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961748PMC
May 2018

Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes.

Cell Stem Cell 2017 Nov 12;21(5):679-693.e6. Epub 2017 Oct 12.

Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, VIB, 3000 Leuven, Belgium; Laboratory for Molecular Cancer Biology, Department of Oncology, KULeuven, 3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.08.003DOI Listing
November 2017

Oxytocin-enforced norm compliance reduces xenophobic outgroup rejection.

Proc Natl Acad Sci U S A 2017 08 14;114(35):9314-9319. Epub 2017 Aug 14.

Division of Medical Psychology, University of Bonn Medical Center, 53105 Bonn, Germany;

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http://dx.doi.org/10.1073/pnas.1705853114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584433PMC
August 2017

Morph or Move? How Distinct Endothelial Cell Responses to Blood Flow Shape Vascular Networks.

Dev Cell 2017 06;41(6):574-576

Max-Delbrück Center for Molecular Medicine, 13125 Berlin, Germany; Vascular Patterning Laboratory, Center for Cancer Biology, VIB, Department of Oncology, KU Leuven, 3000 Leuven, Belgium; DZHK (German Centre for Cardiovascular Research), partner site Berlin, 13347 Berlin, Germany; Berlin Institute of Health, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.06.008DOI Listing
June 2017

A matter of distance-The effect of oxytocin on social discounting is empathy-dependent.

Psychoneuroendocrinology 2017 04 4;78:229-232. Epub 2017 Feb 4.

Department of Psychology, University of Lübeck, Germany.

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http://dx.doi.org/10.1016/j.psyneuen.2017.01.031DOI Listing
April 2017

Pericytes or Mesenchymal Stem Cells: Is That the Question?

Cell Stem Cell 2017 03;20(3):296-297

Integrative Vascular Biology Laboratory, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, 13125 Berlin, Germany; DZHK (German Center for Cardiovascular Research), partner site Berlin; Berlin Institute of Health (BIH), Kapelle-Ufer 2, 10117 Berlin, Germany; Vascular Patterning Laboratory, Center for Cancer Biology, VIB, Department of Oncology, KU Leuven, Herestraat 49, 3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.02.005DOI Listing
March 2017

cAMP-dependent protein kinase A (PKA) regulates angiogenesis by modulating tip cell behavior in a Notch-independent manner.

Development 2016 10;143(19):3582-3590

Vascular Patterning Laboratory, Vesalius Research Center, VIB, Leuven, Belgium Vascular Patterning Laboratory, Vesalius Research Center, Department of Oncology, KU Leuven, Leuven, Belgium Vascular Biology Laboratory, London Research Institute - Cancer Research UK, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London WC2A 3LY, UK Integrative Vascular Biology Lab, Max-Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, Berlin 13125, Germany DZHK (German Center for Cardiovascular Research), partner site Berlin Berlin Institute of Health (BIH), Berlin, Germany

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http://dx.doi.org/10.1242/dev.134767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5087612PMC
October 2016

Blood flow boosts BMP signaling to keep vessels in shape.

J Cell Biol 2016 09;214(7):793-5

Max-Delbrück Center for Molecular Medicine, 13125 Berlin, Germany Department of Oncology, Vascular Patterning Laboratory, Vesalius Research Center, 3000 Leuven, Belgium German Center for Cardiovascular Research, 13347 Berlin, Germany Berlin Institute of Health, 10117 Berlin, Germany

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http://www.jcb.org/lookup/doi/10.1083/jcb.201609038
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http://dx.doi.org/10.1083/jcb.201609038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5037414PMC
September 2016

Glycolytic regulation of cell rearrangement in angiogenesis.

Nat Commun 2016 07 20;7:12240. Epub 2016 Jul 20.

Department of Oncology, Laboratory of Angiogenesis and Vascular Metabolism, KU Leuven, Herestraat 49 box 912, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1038/ncomms12240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961802PMC
July 2016

Incidental fear cues increase monetary loss aversion.

Emotion 2016 Apr 23;16(3):402-12. Epub 2015 Nov 23.

Department of Education and Psychology, Freie Universität Berlin.

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http://dx.doi.org/10.1037/emo0000124DOI Listing
April 2016

Development of siRNA-loaded chitosan nanoparticles targeting Galectin-1 for the treatment of glioblastoma multiforme via intranasal administration.

J Control Release 2016 Apr 21;227:71-81. Epub 2016 Feb 21.

Research Group Experimental Neurosurgery and Neuroanatomy, KU Leuven, Herestraat 49, Leuven 3000, Belgium; Department of Neurosurgery, University Hospitals Leuven, Herestraat 49, Leuven 3000, Belgium.

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http://dx.doi.org/10.1016/j.jconrel.2016.02.032DOI Listing
April 2016

Blood flow drives lumen formation by inverse membrane blebbing during angiogenesis in vivo.

Nat Cell Biol 2016 Apr 29;18(4):443-50. Epub 2016 Feb 29.

Integrative Vascular Biology Laboratory, Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Robert-Rössle-Strasse 10, 13125 Berlin, Germany.

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http://www.nature.com/articles/ncb3320
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http://dx.doi.org/10.1038/ncb3320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485462PMC
April 2016

The Neuropeptide Oxytocin Induces a Social Altruism Bias.

J Neurosci 2015 Nov;35(47):15696-701

Departments of Psychiatry and Division of Medical Psychology, University of Bonn Medical Center, 53105 Bonn, Germany,

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http://www.jneurosci.org/content/35/47/15696.full.pdf
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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.3199-15.2
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http://dx.doi.org/10.1523/JNEUROSCI.3199-15.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6705471PMC
November 2015

Wiring the Vascular Network with Neural Cues: A CNS Perspective.

Neuron 2015 Jul;87(2):271-96

Theodor Kocher Institute, University of Bern, Freiestrasse 1, 3012 Bern, Switzerland.

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http://dx.doi.org/10.1016/j.neuron.2015.06.038DOI Listing
July 2015

Endothelial alpha-parvin controls integrity of developing vasculature and is required for maintenance of cell-cell junctions.

Circ Res 2015 Jun 29;117(1):29-40. Epub 2015 Apr 29.

From the Walter-Brendel-Centre of Experimental Medicine (A.F., B.P., J.K., U.P., E.M.) and Department of Pharmacy (S.Z.), Ludwig-Maximilians University Munich, Munich, Germany; Institute of Anatomy and Vascular Biology, WWU-Münster, Münster, Germany (A.A.T., J.S., H.-J.S.); Department of Molecular Cell Biology, Sanquin Research and Landsteiner Laboratory, Swammerdam Institute for Life Sciences, Amsterdam, The Netherlands (S.H.); Department of Surgery, School of Medicine and Hospital Clinic de Barcelona (IDIBAPS), University of Barcelona, Barcelona, Spain (R.P.C.-M.); and Vascular Biology Laboratory, London Research Institute-Cancer Research United Kingdom, London, United Kingdom (H.G.).

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http://dx.doi.org/10.1161/CIRCRESAHA.117.305818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470528PMC
June 2015

Dynamic endothelial cell rearrangements drive developmental vessel regression.

PLoS Biol 2015 Apr 17;13(4):e1002125. Epub 2015 Apr 17.

Vascular Biology Laboratory, London Research Institute-Cancer Research UK, Lincoln's Inn Laboratories, London, United Kingdom; Usher Institute of Population Health Sciences and Informatics, The University of Edinburgh, No. 9 Edinburgh Bioquarter, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.1002125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401640PMC
April 2015

Quantitative assessment of angiogenesis, perfused blood vessels and endothelial tip cells in the postnatal mouse brain.

Nat Protoc 2015 Jan 11;10(1):53-74. Epub 2014 Dec 11.

Institute of Veterinary Physiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1038/nprot.2015.002DOI Listing
January 2015

Formin-mediated actin polymerization at endothelial junctions is required for vessel lumen formation and stabilization.

Dev Cell 2015 Jan;32(1):123-32

Vascular Patterning Laboratory, Vesalius Research Center, VIB, Department of Oncology, KU Leuven, Herestraat 49, 3000 Leuven, Belgium; Vascular Biology Laboratory, London Research Institute, Cancer Research UK, London WC2A 3LY, UK. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2014.11.017DOI Listing
January 2015

Lack of CCM1 induces hypersprouting and impairs response to flow.

Hum Mol Genet 2014 Dec 2;23(23):6223-34. Epub 2014 Jul 2.

Department of Molecular Medicine, Department of Oncological Sciences, Division of Cardiovascular Medicine, Salt Lake City 84132, USA and The Key Laboratory for Human Disease Gene Study of Sichuan Province, Institute of Laboratory Medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, Sichuan 610072, China

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http://dx.doi.org/10.1093/hmg/ddu342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222362PMC
December 2014

Tissue guidance without filopodia.

Commun Integr Biol 2014 9;7:e28820. Epub 2014 Apr 9.

Department of Oncology; Vascular Patterning Laboratory; VRC; Leuven, Belgium ; VIB; Vascular Patterning Laboratory; VRC; Leuven, Belgium.

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http://www.tandfonline.com/doi/abs/10.4161/cib.28820
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http://dx.doi.org/10.4161/cib.28820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203535PMC
October 2014

Tumor vessel normalization by chloroquine independent of autophagy.

Cancer Cell 2014 Aug;26(2):190-206

Department of Oncology, Laboratory of Angiogenesis and Neurovascular Link, KU Leuven, B-3000 Leuven, Belgium; Vesalius Research Center, Laboratory of Angiogenesis and Neurovascular Link, VIB, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.ccr.2014.06.025DOI Listing
August 2014

The role of differential VE-cadherin dynamics in cell rearrangement during angiogenesis.

Nat Cell Biol 2014 Apr 23;16(4):309-21. Epub 2014 Mar 23.

1] Vascular Biology Laboratory, London Research Institute, Cancer Research UK, London WC2A 3LY, UK [2] Vascular Patterning Laboratory, VIB3-Vesalius Research Center & CMVB, Department of Oncology, KU Leuven Campus Gasthuisberg O&N4, Herestraat 49 box 912 B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1038/ncb2926DOI Listing
April 2014

Glioma-derived galectin-1 regulates innate and adaptive antitumor immunity.

Int J Cancer 2014 Feb 4;134(4):873-84. Epub 2013 Sep 4.

Department of Neurosciences, Laboratory of Experimental Neurosurgery and Neuroanatomy, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1002/ijc.28426DOI Listing
February 2014

Partial and transient reduction of glycolysis by PFKFB3 blockade reduces pathological angiogenesis.

Cell Metab 2014 Jan 12;19(1):37-48. Epub 2013 Dec 12.

Laboratory of Angiogenesis and Neurovascular link, Vesalius Research Center, Department of Oncology, University of Leuven, Leuven 3000, Belgium; Laboratory of Angiogenesis and Neurovascular link, Vesalius Research Center, VIB, Leuven 3000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2013.11.008DOI Listing
January 2014

Music-evoked incidental happiness modulates probability weighting during risky lottery choices.

Front Psychol 2014 Jan 7;4:981. Epub 2014 Jan 7.

Cluster of Excellence "Languages of Emotion," Freie Universität Berlin Berlin, Germany ; Department of Education and Psychology, Freie Universität Berlin Berlin, Germany.

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http://dx.doi.org/10.3389/fpsyg.2013.00981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882660PMC
January 2014

Filopodia are dispensable for endothelial tip cell guidance.

Development 2013 Oct;140(19):4031-40

KU Leuven, Department of Oncology, Vesalius Research Centre, Vascular Patterning Lab, Herestraat 49, 3000 Leuven, Belgium.

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http://dev.biologists.org/lookup/doi/10.1242/dev.097352
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http://dx.doi.org/10.1242/dev.097352DOI Listing
October 2013

Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis.

J Exp Med 2013 Sep 16;210(10):1937-45. Epub 2013 Sep 16.

Vascular Signaling Laboratory; and 2 Translational Research Laboratory, Catalan Institute of Oncology, Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), 08907 L'Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1084/jem.20121571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782054PMC
September 2013

Introduction to the ECR special angiogenesis issue.

Exp Cell Res 2013 May 15;319(9):1239. Epub 2013 Mar 15.

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http://dx.doi.org/10.1016/j.yexcr.2013.03.014DOI Listing
May 2013

Visualization of endothelial actin cytoskeleton in the mouse retina.

PLoS One 2012 24;7(10):e47488. Epub 2012 Oct 24.

Walter Brendel Centre of Experimental Medicine and Munich Heart Alliance, Ludwig-Maximilians University Munich, Munich, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047488PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480364PMC
April 2013

VEGF and Notch in tip and stalk cell selection.

Cold Spring Harb Perspect Med 2013 Jan 1;3(1):a006569. Epub 2013 Jan 1.

Vascular Biology Laboratory, London Research Institute, Lincoln's Inn Fields Laboratories, London WC2A 3LY, UK.

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http://perspectivesinmedicine.cshlp.org/lookup/doi/10.1101/c
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http://dx.doi.org/10.1101/cshperspect.a006569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530037PMC
January 2013

Tissue engineering: Blood vessels on a chip.

Nature 2012 Aug;488(7412):465-6

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http://dx.doi.org/10.1038/488465aDOI Listing
August 2012

N-CAM exhibits a regulatory function in pathological angiogenesis in oxygen induced retinopathy.

PLoS One 2011 17;6(10):e26026. Epub 2011 Oct 17.

Department of Medical Biochemistry, Sahlgrenska Academy at Gothenburg University, Göteborg, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0026026PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3197149PMC
April 2012

Endothelial development taking shape.

Curr Opin Cell Biol 2011 Dec 1;23(6):676-85. Epub 2011 Nov 1.

Vascular Patterning Laboratory, Vesalius Research Center, VIB, B-3000 Leuven, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S09550674110013
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http://dx.doi.org/10.1016/j.ceb.2011.10.002DOI Listing
December 2011

Coordinating cell behaviour during blood vessel formation.

Development 2011 Nov 28;138(21):4569-83. Epub 2011 Sep 28.

Vascular Patterning Laboratory, Vesalius Research Center, VIB, 3000 Leuven, Belgium.

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http://dev.biologists.org/cgi/doi/10.1242/dev.062323
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http://dx.doi.org/10.1242/dev.062323DOI Listing
November 2011

VEGFR-3 controls tip to stalk conversion at vessel fusion sites by reinforcing Notch signalling.

Nat Cell Biol 2011 Sep 11;13(10):1202-13. Epub 2011 Sep 11.

Molecular/Cancer Biology Laboratory, Institute for Molecular Medicine Finland, Research Programs Unit and Department of Pathology, Haartman Institute, Biomedicum Helsinki, PO Box 63 (Haartmaninkatu 8), 00014 University of Helsinki, Finland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3261765PMC
http://dx.doi.org/10.1038/ncb2331DOI Listing
September 2011

Basic and therapeutic aspects of angiogenesis.

Cell 2011 Sep;146(6):873-87

Vascular Epigenetics Group, Institute for Cardiovascular Regeneration, Center of Molecular Medicine, Goethe University, D-60590 Frankfurt, Germany.

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http://dx.doi.org/10.1016/j.cell.2011.08.039DOI Listing
September 2011

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting.

Nat Cell Biol 2010 Oct 26;12(10):943-53. Epub 2010 Sep 26.

Vascular Biology Laboratory, London Research Institute, Cancer Research UK, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK.

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http://pbsb.med.cornell.edu/pdfs/nature_jakobsson.pdf
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http://www.nature.com/doifinder/10.1038/ncb2103
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http://dx.doi.org/10.1038/ncb2103DOI Listing
October 2010

VEGFRs and Notch: a dynamic collaboration in vascular patterning.

Biochem Soc Trans 2009 Dec;37(Pt 6):1233-6

Vascular Biology Laboratory, London Research Institute - Cancer Research UK, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1042/BST0371233DOI Listing
December 2009

Vascular morphogenesis: a Wnt for every vessel?

Curr Opin Genet Dev 2009 Oct 26;19(5):476-83. Epub 2009 Oct 26.

Vascular Biology Laboratory, London Research Institute-Cancer Research UK, 44 Lincoln's Inn Fields, WC2A 3PX London, UK.

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http://dx.doi.org/10.1016/j.gde.2009.09.004DOI Listing
October 2009

Tipping the balance: robustness of tip cell selection, migration and fusion in angiogenesis.

PLoS Comput Biol 2009 Oct 30;5(10):e1000549. Epub 2009 Oct 30.

Biomolecular Modelling Laboratory, Cancer Research UK London Research Institute, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pcbi.1000549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762315PMC
October 2009

Peripheral mural cell recruitment requires cell-autonomous heparan sulfate.

Blood 2009 Jul 27;114(4):915-24. Epub 2009 Apr 27.

Vascular Biology Laboratory, London Research Institute-Cancer Research UK, 44 Lincoln's Inn Fields, London, United Kingdom.

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http://dx.doi.org/10.1182/blood-2008-10-186239DOI Listing
July 2009

Angiogenesis: a team effort coordinated by notch.

Dev Cell 2009 Feb;16(2):196-208

London Research Institute, Cancer Research UK, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S153458070900043
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http://dx.doi.org/10.1016/j.devcel.2009.01.015DOI Listing
February 2009

VEGF and endothelial guidance in angiogenic sprouting.

Authors:
Holger Gerhardt

Organogenesis 2008 Oct;4(4):241-6

Vascular Biology Laboratory; London Research Institute; Cancer Research UK; Lincoln's Inn Fields Laboratories; London UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634329PMC
http://dx.doi.org/10.4161/org.4.4.7414DOI Listing
October 2008

Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.

Nature 2008 May 30;453(7195):662-6. Epub 2008 Apr 30.

Centre for Cell Signalling, Institute of Cancer, Queen Mary, University of London, Charterhouse Square, London EC1M 6BQ, UK.

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http://dx.doi.org/10.1038/nature06892DOI Listing
May 2008

Dendritic cell expression of the Notch ligand jagged2 is not essential for Th2 response induction in vivo.

Eur J Immunol 2008 Apr;38(4):1043-9

Institute of Immunology and Infection Research, School of Biological Sciences, University of Edinburgh, Edinburgh, UK.

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http://doi.wiley.com/10.1002/eji.200737335
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http://dx.doi.org/10.1002/eji.200737335DOI Listing
April 2008

Therapeutic antibodies targeting angiomotin inhibit angiogenesis in vivo.

FASEB J 2008 Mar 5;22(3):880-9. Epub 2007 Nov 5.

Department of Oncology and Pathology, Cancer Centre Karolinska, Karolinska Institute, SE 17176, Stockholm, Sweden.

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http://www.fasebj.org/content/22/3/880.full.pdf
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http://www.fasebj.org/cgi/doi/10.1096/fj.07-9509com
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http://dx.doi.org/10.1096/fj.07-9509comDOI Listing
March 2008

Growth factor gradients in vascular patterning.

Novartis Found Symp 2007 ;283:194-201; discussion 201-6, 238-41

Vascular Biology Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1002/9780470319413.ch15DOI Listing
March 2008

Agent-based simulation of notch-mediated tip cell selection in angiogenic sprout initialisation.

J Theor Biol 2008 Jan 19;250(1):25-36. Epub 2007 Sep 19.

Biomolecular Modelling Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London, WC2A 3PX, UK.

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http://dx.doi.org/10.1016/j.jtbi.2007.09.015DOI Listing
January 2008