Ho Jeong Kwon

Ho Jeong Kwon

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Ho Jeong Kwon

Publications by authors named "Ho Jeong Kwon"

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Improved production of clavulanic acid by reverse engineering and overexpression of the regulatory genes in an industrial Streptomyces clavuligerus strain.

J Ind Microbiol Biotechnol 2019 Aug 4;46(8):1205-1215. Epub 2019 Jun 4.

Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, 03760, Republic of Korea.

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http://dx.doi.org/10.1007/s10295-019-02196-0DOI Listing
August 2019

Design, synthesis, and biological evaluation of novel pyrrolo[1,2-a]pyrazine derivatives.

Bioorg Med Chem Lett 2019 Jun 28;29(11):1350-1356. Epub 2019 Mar 28.

College of Pharmacy and Yonsei Institute of Pharmaceutical Sciences, Yonsei University, Incheon, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.03.044DOI Listing
June 2019

Reverse Chemical Proteomics Identifies an Unanticipated Human Target of the Antimalarial Artesunate.

ACS Chem Biol 2019 Apr 19;14(4):636-643. Epub 2019 Mar 19.

Department of Molecular Sciences , Macquarie University , Sydney , NSW 2109 , Australia.

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http://dx.doi.org/10.1021/acschembio.8b01004DOI Listing
April 2019

Acid ceramidase, an emerging target for anti-cancer and anti-angiogenesis.

Arch Pharm Res 2019 Mar 19;42(3):232-243. Epub 2019 Jan 19.

Chemical Genomics Global Research Laboratory, Department of Biotechnology, College of Life Science & Biotechnology, Yonsei University, Seoul, 120-749, Republic of Korea.

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http://dx.doi.org/10.1007/s12272-019-01114-3DOI Listing
March 2019

A Guanidine-Based Synthetic Compound Suppresses Angiogenesis via Inhibition of Acid Ceramidase.

ACS Chem Biol 2019 01 19;14(1):11-19. Epub 2018 Dec 19.

Chemical Genomics Global Research Laboratory, Department of Biotechnology, College of Life Science & Biotechnology , Yonsei University , Seoul 120-749 , Republic of Korea.

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http://pubs.acs.org/doi/10.1021/acschembio.8b00558
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http://dx.doi.org/10.1021/acschembio.8b00558DOI Listing
January 2019

Eupatilin rescues ciliary transition zone defects to ameliorate ciliopathy-related phenotypes.

J Clin Invest 2018 08 23;128(8):3642-3648. Epub 2018 Jul 23.

Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, South Korea.

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http://dx.doi.org/10.1172/JCI99232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063470PMC
August 2018

Hsa-miR-10a-5p downregulation in mutant UQCRB-expressing cells promotes the cholesterol biosynthesis pathway.

Sci Rep 2018 Aug 17;8(1):12407. Epub 2018 Aug 17.

Chemical Genomics Global Research Lab., Department of Biotechnology, College of Life Science & Biotechnology, Yonsei University, Seoul, 120-749, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-018-30530-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098055PMC
August 2018

Biobank integration of large-scale clinical and histopathology melanoma studies within the European Cancer Moonshot Lund Center.

Clin Transl Med 2018 Aug 20;7(1):28. Epub 2018 Aug 20.

Clinical Protein Science & Imaging, Biomedical Center, Dept. of Biomedical Engineering, Lund University, BMC C13, 221 84, Lund, Sweden.

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http://dx.doi.org/10.1186/s40169-018-0203-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6098996PMC
August 2018

Downregulation of mitochondrial UQCRB inhibits cancer stem cell-like properties in glioblastoma.

Int J Oncol 2018 Jan 6;52(1):241-251. Epub 2017 Nov 6.

Department of BT-Convergent Pharmaceutical Engineering, Sun Moon University, Tangjeong-myeon, Asan-si, Chungnam 336-708, Republic of Korea.

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http://dx.doi.org/10.3892/ijo.2017.4191DOI Listing
January 2018

Chemical proteomics, an integrated research engine for exploring drug-target-phenotype interactions.

Proteome Sci 2018 9;16. Epub 2018 Jan 9.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW 2109 Australia.

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http://dx.doi.org/10.1186/s12953-017-0129-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759357PMC
January 2018

Development of Turmeric Extract Nanoemulsions and Their Incorporation into Canned Ham.

Korean J Food Sci Anim Resour 2017 31;37(6):889-897. Epub 2017 Dec 31.

Department of Food Science and Technology, Keimyung University, Daegu 42601, Korea.

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http://koreascience.or.kr/journal/view.jsp?kj=CSSPBQ&py=
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http://dx.doi.org/10.5851/kosfa.2017.37.6.889DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932933PMC
December 2017

Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth.

Cancer Lett 2017 11 18;409:91-103. Epub 2017 Sep 18.

Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China; Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA; The SJ Yan and HJ Mao Laboratory of Chemical Biology, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2017.09.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5634947PMC
November 2017

Mitochondrial UQCRB as a new molecular prognostic biomarker of human colorectal cancer.

Exp Mol Med 2017 11 17;49(11):e391. Epub 2017 Nov 17.

Chemical Genomics Global Research Laboratory, Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.

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http://dx.doi.org/10.1038/emm.2017.152DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5704184PMC
November 2017

Two cyclic hexapeptides from Penicillium sp. FN070315 with antiangiogenic activities.

PLoS One 2017 26;12(9):e0184339. Epub 2017 Sep 26.

Anticancer Agent Research Center, Korea Research Institute of Bioscience and Biotechnology, Cheongju, Republic of Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0184339PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614539PMC
October 2017

Approaches for discovering novel bioactive small molecules targeting autophagy.

Expert Opin Drug Discov 2017 09 30;12(9):909-923. Epub 2017 Jul 30.

a Chemical Genomics Global Research Laboratory, Department of Biotechnology, College of Life Science and Biotechnology , Yonsei University , Seoul , Republic of Korea.

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http://dx.doi.org/10.1080/17460441.2017.1349751DOI Listing
September 2017

Daptomycin, a last-resort antibiotic, binds ribosomal protein S19 in humans.

Proteome Sci 2016 1;15:16. Epub 2017 Jul 1.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW 2109 Australia.

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http://dx.doi.org/10.1186/s12953-017-0124-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494143PMC
July 2017

Curcumin and Curcuma longa L. extract ameliorate lipid accumulation through the regulation of the endoplasmic reticulum redox and ER stress.

Sci Rep 2017 07 26;7(1):6513. Epub 2017 Jul 26.

Department of Pharmacology and New Drug Development Institute, Chonbuk National University Medical School, Jeonju, Chonbuk, 561-180, Republic of Korea.

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http://dx.doi.org/10.1038/s41598-017-06872-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5529367PMC
July 2017

The effect of indatraline on angiogenesis suppression through HIF-1α-mediated VEGF inhibition.

Biochem Biophys Res Commun 2017 04 17;485(2):349-354. Epub 2017 Feb 17.

Chemical Genomics Global Research Laboratory, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea; Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.02.077DOI Listing
April 2017

FK506, an Immunosuppressive Drug, Induces Autophagy by Binding to the V-ATPase Catalytic Subunit A in Neuronal Cells.

J Proteome Res 2017 01 17;16(1):55-64. Epub 2016 Nov 17.

Global Research Laboratory, Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University , Seoul 120-749, Korea.

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http://dx.doi.org/10.1021/acs.jproteome.6b00638DOI Listing
January 2017

Building the basis for proteomics in personalized medicine for targeted treatment.

Clin Transl Med 2016 Dec 20;5(1):19. Epub 2016 May 20.

Clinical Protein Science & Imaging, Biomedical Center, Department of Biomedical Engineering, Lund University, BMC D13, SE-221 84, Lund, Sweden.

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http://dx.doi.org/10.1186/s40169-016-0096-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896889PMC
December 2016

Tricin, 4',5,7-trihydroxy-3',5'-dimethoxyflavone, exhibits potent antiangiogenic activity in vitro.

Int J Oncol 2016 Oct 3;49(4):1497-504. Epub 2016 Aug 3.

Department of BT-Convergent Pharmaceutical Engineering, Sun Moon University, Chungnam 336-708, Republic of Korea.

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http://dx.doi.org/10.3892/ijo.2016.3645DOI Listing
October 2016

Antidepressant indatraline induces autophagy and inhibits restenosis via suppression of mTOR/S6 kinase signaling pathway.

Sci Rep 2016 10 3;6:34655. Epub 2016 Oct 3.

Chemical Genomics Global Research Laboratory, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science &Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1038/srep34655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5046148PMC
October 2016

Inhibition of 5-lipoxygenase suppresses vascular endothelial growth factor-induced angiogenesis in endothelial cells.

Biochem Biophys Res Commun 2016 09 13;478(3):1117-22. Epub 2016 Aug 13.

Chemical Genomics Global Research Laboratory, Department of Biotechnology, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.08.078DOI Listing
September 2016

Turmeric extract and its active compound, curcumin, protect against chronic CCl4-induced liver damage by enhancing antioxidation.

BMC Complement Altern Med 2016 Aug 26;16(1):316. Epub 2016 Aug 26.

Department of Pharmacology and New Drug Development Institute, Chonbuk National University Medical School, Jeonju, Chonbuk, 561-180, Republic of Korea.

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http://dx.doi.org/10.1186/s12906-016-1307-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5000414PMC
August 2016

The Small Molecule R-(-)-β-O-Methylsynephrine Binds to Nucleoporin 153 kDa and Inhibits Angiogenesis.

Int J Biol Sci 2015 16;11(9):1088-99. Epub 2015 Jul 16.

1. Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea ; 6. Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, Republic of Korea.

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http://www.ijbs.com/v11p1088.htm
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http://dx.doi.org/10.7150/ijbs.10603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515819PMC
May 2016

Discovery of novel drug targets and their functions using phenotypic screening of natural products.

J Ind Microbiol Biotechnol 2016 Mar 12;43(2-3):221-31. Epub 2015 Sep 12.

Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, 120-749, Republic of Korea.

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http://dx.doi.org/10.1007/s10295-015-1681-yDOI Listing
March 2016

Target deconvolution of bioactive small molecules: the heart of chemical biology and drug discovery.

Arch Pharm Res 2015 Sep 4;38(9):1627-41. Epub 2015 Jun 4.

Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-749, Republic of Korea.

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http://dx.doi.org/10.1007/s12272-015-0618-3DOI Listing
September 2015

Cell-permeable mitochondrial ubiquinol-cytochrome c reductase binding protein induces angiogenesis in vitro and in vivo.

Cancer Lett 2015 Sep 25;366(1):52-60. Epub 2015 Jun 25.

Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea; Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2015.06.013DOI Listing
September 2015

Antiangiogenic activity of herboxidiene via downregulation of vascular endothelial growth factor receptor-2 and hypoxia-inducible factor-1α.

Arch Pharm Res 2015 Sep 21;38(9):1728-35. Epub 2015 Jul 21.

Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-749, Republic of Korea.

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http://link.springer.com/10.1007/s12272-015-0625-4
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http://dx.doi.org/10.1007/s12272-015-0625-4DOI Listing
September 2015

Drug compound characterization by mass spectrometry imaging in cancer tissue.

Arch Pharm Res 2015 Sep 23;38(9):1718-27. Epub 2015 Jul 23.

Clinical Protein Science & Imaging, Biomedical Centre, Department of Biomedical Engineering, Lund University, BMC D13, Lund, Sweden.

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http://dx.doi.org/10.1007/s12272-015-0627-2DOI Listing
September 2015

Preface to this special issue on chemical biology and drug discovery.

Authors:
Ho Jeong Kwon

Arch Pharm Res 2015 Sep;38(9):1561-2

Chemical Genomics National Research Laboratory, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, 120-749, Republic of Korea.

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http://dx.doi.org/10.1007/s12272-015-0656-xDOI Listing
September 2015

NNC 55-0396, a T-type Ca2+ channel inhibitor, inhibits angiogenesis via suppression of hypoxia-inducible factor-1α signal transduction.

J Mol Med (Berl) 2015 May 4;93(5):499-509. Epub 2014 Dec 4.

Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul, 120-749, South Korea.

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http://dx.doi.org/10.1007/s00109-014-1235-1DOI Listing
May 2015

Antiangiogenic activity of the lipophilic antimicrobial peptides from an endophytic bacterial strain isolated from red pepper leaf.

Mol Cells 2015 Mar 30;38(3):273-8. Epub 2014 Dec 30.

Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.

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http://www.molcells.org/journal/view.html?doi=10.14348/molce
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http://dx.doi.org/10.14348/molcells.2015.2320DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4363728PMC
March 2015

HIF-1α suppressing small molecule, LW6, inhibits cancer cell growth by binding to calcineurin b homologous protein 1.

Biochem Biophys Res Commun 2015 Feb 17;458(1):14-20. Epub 2015 Jan 17.

Chemical Genomics National Research Laboratory, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul 120-752, Republic of Korea; Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, Republic of Korea. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X150005
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http://dx.doi.org/10.1016/j.bbrc.2015.01.031DOI Listing
February 2015

Convallatoxin, a dual inducer of autophagy and apoptosis, inhibits angiogenesis in vitro and in vivo.

PLoS One 2014 24;9(3):e91094. Epub 2014 Mar 24.

Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science & Biotechnology, Yonsei University, Seoul, Korea.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091094PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963847PMC
January 2015

A mutation in the mitochondrial protein UQCRB promotes angiogenesis through the generation of mitochondrial reactive oxygen species.

Biochem Biophys Res Commun 2014 Dec 11;455(3-4):290-7. Epub 2014 Nov 11.

Chemical Genomics National Research Lab., Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea; Department of Internal Medicine, Yonsei University College of Medicine, Seoul 120-752, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.11.005DOI Listing
December 2014

A new histone deacetylase inhibitor improves liver fibrosis in BDL rats through suppression of hepatic stellate cells.

Br J Pharmacol 2014 Nov 5;171(21):4820-30. Epub 2014 Sep 5.

Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea; Department of Surgery, Yonsei University College of Medicine, Seoul, Korea.

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http://dx.doi.org/10.1111/bph.12590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232907PMC
November 2014

The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway.

Exp Cell Res 2014 Oct 14;327(2):264-75. Epub 2014 Aug 14.

Department of Biomedical Laboratory Science, Kyungbok University, Sinbuk-myeon, Pochen, Gyeonggi 487-717, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.yexcr.2014.07.037DOI Listing
October 2014

Development of a novel class of mitochondrial ubiquinol-cytochrome c reductase binding protein (UQCRB) modulators as promising antiangiogenic leads.

J Med Chem 2014 Oct 22;57(19):7990-8. Epub 2014 Sep 22.

Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University , Seoul 120-749, Republic of Korea.

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http://pubs.acs.org/doi/10.1021/jm500863j
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http://dx.doi.org/10.1021/jm500863jDOI Listing
October 2014

Purpurin inhibits adipocyte-derived leucine aminopeptidase and angiogenesis in a zebrafish model.

Biochem Biophys Res Commun 2014 Jul 10;450(1):561-7. Epub 2014 Jun 10.

Chemical Genomics National Research Laboratory, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea; Department of Internal Medicine, College of Medicine, Yonsei University, Seoul 120-752, Republic of Korea. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.06.017DOI Listing
July 2014

The 7th Japan-Korea chemical biology symposium: chemical biology of natural bioactive molecules.

ACS Chem Biol 2014 May;9(5):1070-4

Institute of Biomolecule Reconstruction, Sun Moon University , Asansi, Chungnam 336-708, Korea.

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http://dx.doi.org/10.1021/cb5002558DOI Listing
May 2014

A new anti-angiogenic small molecule, G0811, inhibits angiogenesis via targeting hypoxia inducible factor (HIF)-1α signal transduction.

Biochem Biophys Res Commun 2013 Nov 23;441(2):399-404. Epub 2013 Oct 23.

Chemical Genomics National Research Laboratory, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2013.10.075DOI Listing
November 2013

Mitochondrial UQCRB regulates VEGFR2 signaling in endothelial cells.

J Mol Med (Berl) 2013 Sep 25;91(9):1117-28. Epub 2013 May 25.

Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul, 120-749, South Korea.

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http://dx.doi.org/10.1007/s00109-013-1049-6DOI Listing
September 2013

Mutational biosynthesis of a FK506 analogue containing a non-natural starter unit.

Mol Biosyst 2013 May;9(5):944-7

Department of Chemistry and Nano Science, Ewha Womans University, Seoul 120-750, Republic of Korea.

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http://dx.doi.org/10.1039/c2mb25419kDOI Listing
May 2013

Exploring the role of mitochondrial UQCRB in angiogenesis using small molecules.

Mol Biosyst 2013 May;9(5):930-9

Chemical Genomics National Research Laboratory, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-749, Korea.

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http://dx.doi.org/10.1039/c3mb25426gDOI Listing
May 2013

Functional inhibition of UQCRB suppresses angiogenesis in zebrafish.

Biochem Biophys Res Commun 2013 Apr 28;433(4):396-400. Epub 2013 Feb 28.

Chemical Genomics National Research Laboratory, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2013.02.082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691074PMC
April 2013

Discovery of pyridone-based histone deacetylase inhibitors: approaches for metabolic stability.

ChemMedChem 2013 Feb 4;8(2):272-9. Epub 2013 Jan 4.

Translational Research Center for Protein Function Control (TRCP), Department of Biotechnology and Department of Biomedical Sciences (WCU Program), Yonsei University, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1002/cmdc.201200529DOI Listing
February 2013

Property-based optimization of hydroxamate-based γ-lactam HDAC inhibitors to improve their metabolic stability and pharmacokinetic profiles.

J Med Chem 2012 Dec 4;55(23):10766-70. Epub 2012 Dec 4.

Severance Integrative Research Institute for Cerebral & Cardiovascular Disease, Yonsei University Health System, 250 Seongsanno, Seodaemun-Gu, Seoul 120-752, Republic of Korea.

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http://dx.doi.org/10.1021/jm3009376DOI Listing
December 2012

Verrulactones A and B, new inhibitors of Staphylococcus aureus enoyl-ACP reductase produced by Penicillium verruculosum F375.

Bioorg Med Chem Lett 2012 Apr 9;22(7):2503-6. Epub 2012 Feb 9.

Korea Research Institute of Bioscience and Biotechnology, PO Box 115, Yusong, Daejeon 305-806, Republic of Korea.

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http://dx.doi.org/10.1016/j.bmcl.2012.02.001DOI Listing
April 2012

Matairesinol inhibits angiogenesis via suppression of mitochondrial reactive oxygen species.

Biochem Biophys Res Commun 2012 Apr 28;421(1):76-80. Epub 2012 Mar 28.

Chemical Genomics National Research Laboratory, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2012.03.114DOI Listing
April 2012

Guidelines for the use and interpretation of assays for monitoring autophagy.

Authors:
Daniel J Klionsky Fabio C Abdalla Hagai Abeliovich Robert T Abraham Abraham Acevedo-Arozena Khosrow Adeli Lotta Agholme Maria Agnello Patrizia Agostinis Julio A Aguirre-Ghiso Hyung Jun Ahn Ouardia Ait-Mohamed Slimane Ait-Si-Ali Takahiko Akematsu Shizuo Akira Hesham M Al-Younes Munir A Al-Zeer Matthew L Albert Roger L Albin Javier Alegre-Abarrategui Maria Francesca Aleo Mehrdad Alirezaei Alexandru Almasan Maylin Almonte-Becerril Atsuo Amano Ravi Amaravadi Shoba Amarnath Amal O Amer Nathalie Andrieu-Abadie Vellareddy Anantharam David K Ann Shailendra Anoopkumar-Dukie Hiroshi Aoki Nadezda Apostolova Giuseppe Arancia John P Aris Katsuhiko Asanuma Nana Y O Asare Hisashi Ashida Valerie Askanas David S Askew Patrick Auberger Misuzu Baba Steven K Backues Eric H Baehrecke Ben A Bahr Xue-Yuan Bai Yannick Bailly Robert Baiocchi Giulia Baldini Walter Balduini Andrea Ballabio Bruce A Bamber Edward T W Bampton Gábor Bánhegyi Clinton R Bartholomew Diane C Bassham Robert C Bast Henri Batoko Boon-Huat Bay Isabelle Beau Daniel M Béchet Thomas J Begley Christian Behl Christian Behrends Soumeya Bekri Bryan Bellaire Linda J Bendall Luca Benetti Laura Berliocchi Henri Bernardi Francesca Bernassola Sébastien Besteiro Ingrid Bhatia-Kissova Xiaoning Bi Martine Biard-Piechaczyk Janice S Blum Lawrence H Boise Paolo Bonaldo David L Boone Beat C Bornhauser Karina R Bortoluci Ioannis Bossis Frédéric Bost Jean-Pierre Bourquin Patricia Boya Michaël Boyer-Guittaut Peter V Bozhkov Nathan R Brady Claudio Brancolini Andreas Brech Jay E Brenman Ana Brennand Emery H Bresnick Patrick Brest Dave Bridges Molly L Bristol Paul S Brookes Eric J Brown John H Brumell Nicola Brunetti-Pierri Ulf T Brunk Dennis E Bulman Scott J Bultman Geert Bultynck Lena F Burbulla Wilfried Bursch Jonathan P Butchar Wanda Buzgariu Sergio P Bydlowski Ken Cadwell Monika Cahová Dongsheng Cai Jiyang Cai Qian Cai Bruno Calabretta Javier Calvo-Garrido Nadine Camougrand Michelangelo Campanella Jenny Campos-Salinas Eleonora Candi Lizhi Cao Allan B Caplan Simon R Carding Sandra M Cardoso Jennifer S Carew Cathleen R Carlin Virginie Carmignac Leticia A M Carneiro Serena Carra Rosario A Caruso Giorgio Casari Caty Casas Roberta Castino Eduardo Cebollero Francesco Cecconi Jean Celli Hassan Chaachouay Han-Jung Chae Chee-Yin Chai David C Chan Edmond Y Chan Raymond Chuen-Chung Chang Chi-Ming Che Ching-Chow Chen Guang-Chao Chen Guo-Qiang Chen Min Chen Quan Chen Steve S-L Chen WenLi Chen Xi Chen Xiangmei Chen Xiequn Chen Ye-Guang Chen Yingyu Chen Yongqiang Chen Yu-Jen Chen Zhixiang Chen Alan Cheng Christopher H K Cheng Yan Cheng Heesun Cheong Jae-Ho Cheong Sara Cherry Russ Chess-Williams Zelda H Cheung Eric Chevet Hui-Ling Chiang Roberto Chiarelli Tomoki Chiba Lih-Shen Chin Shih-Hwa Chiou Francis V Chisari Chi Hin Cho Dong-Hyung Cho Augustine M K Choi DooSeok Choi Kyeong Sook Choi Mary E Choi Salem Chouaib Divaker Choubey Vinay Choubey Charleen T Chu Tsung-Hsien Chuang Sheau-Huei Chueh Taehoon Chun Yong-Joon Chwae Mee-Len Chye Roberto Ciarcia Maria R Ciriolo Michael J Clague Robert S B Clark Peter G H Clarke Robert Clarke Patrice Codogno Hilary A Coller María I Colombo Sergio Comincini Maria Condello Fabrizio Condorelli Mark R Cookson Graham H Coombs Isabelle Coppens Ramon Corbalan Pascale Cossart Paola Costelli Safia Costes Ana Coto-Montes Eduardo Couve Fraser P Coxon James M Cregg José L Crespo Marianne J Cronjé Ana Maria Cuervo Joseph J Cullen Mark J Czaja Marcello D'Amelio Arlette Darfeuille-Michaud Lester M Davids Faith E Davies Massimo De Felici John F de Groot Cornelis A M de Haan Luisa De Martino Angelo De Milito Vincenzo De Tata Jayanta Debnath Alexei Degterev Benjamin Dehay Lea M D Delbridge Francesca Demarchi Yi Zhen Deng Jörn Dengjel Paul Dent Donna Denton Vojo Deretic Shyamal D Desai Rodney J Devenish Mario Di Gioacchino Gilbert Di Paolo Chiara Di Pietro Guillermo Díaz-Araya Inés Díaz-Laviada Maria T Diaz-Meco Javier Diaz-Nido Ivan Dikic Savithramma P Dinesh-Kumar Wen-Xing Ding Clark W Distelhorst Abhinav Diwan Mojgan Djavaheri-Mergny Svetlana Dokudovskaya Zheng Dong Frank C Dorsey Victor Dosenko James J Dowling Stephen Doxsey Marlène Dreux Mark E Drew Qiuhong Duan Michel A Duchosal Karen Duff Isabelle Dugail Madeleine Durbeej Michael Duszenko Charles L Edelstein Aimee L Edinger Gustavo Egea Ludwig Eichinger N Tony Eissa Suhendan Ekmekcioglu Wafik S El-Deiry Zvulun Elazar Mohamed Elgendy Lisa M Ellerby Kai Er Eng Anna-Mart Engelbrecht Simone Engelender Jekaterina Erenpreisa Ricardo Escalante Audrey Esclatine Eeva-Liisa Eskelinen Lucile Espert Virginia Espina Huizhou Fan Jia Fan Qi-Wen Fan Zhen Fan Shengyun Fang Yongqi Fang Manolis Fanto Alessandro Fanzani Thomas Farkas Jean-Claude Farré Mathias Faure Marcus Fechheimer Carl G Feng Jian Feng Qili Feng Youji Feng László Fésüs Ralph Feuer Maria E Figueiredo-Pereira Gian Maria Fimia Diane C Fingar Steven Finkbeiner Toren Finkel Kim D Finley Filomena Fiorito Edward A Fisher Paul B Fisher Marc Flajolet Maria L Florez-McClure Salvatore Florio Edward A Fon Francesco Fornai Franco Fortunato Rati Fotedar Daniel H Fowler Howard S Fox Rodrigo Franco Lisa B Frankel Marc Fransen José M Fuentes Juan Fueyo Jun Fujii Kozo Fujisaki Eriko Fujita Mitsunori Fukuda Ruth H Furukawa Matthias Gaestel Philippe Gailly Malgorzata Gajewska Brigitte Galliot Vincent Galy Subramaniam Ganesh Barry Ganetzky Ian G Ganley Fen-Biao Gao George F Gao Jinming Gao Lorena Garcia Guillermo Garcia-Manero Mikel Garcia-Marcos Marjan Garmyn Andrei L Gartel Evelina Gatti Mathias Gautel Thomas R Gawriluk Matthew E Gegg Jiefei Geng Marc Germain Jason E Gestwicki David A Gewirtz Saeid Ghavami Pradipta Ghosh Anna M Giammarioli Alexandra N Giatromanolaki Spencer B Gibson Robert W Gilkerson Michael L Ginger Henry N Ginsberg Jakub Golab Michael S Goligorsky Pierre Golstein Candelaria Gomez-Manzano Ebru Goncu Céline Gongora Claudio D Gonzalez Ramon Gonzalez Cristina González-Estévez Rosa Ana González-Polo Elena Gonzalez-Rey Nikolai V Gorbunov Sharon Gorski Sandro Goruppi Roberta A Gottlieb Devrim Gozuacik Giovanna Elvira Granato Gary D Grant Kim N Green Aleš Gregorc Frédéric Gros Charles Grose Thomas W Grunt Philippe Gual Jun-Lin Guan Kun-Liang Guan Sylvie M Guichard Anna S Gukovskaya Ilya Gukovsky Jan Gunst Asa B Gustafsson Andrew J Halayko Amber N Hale Sandra K Halonen Maho Hamasaki Feng Han Ting Han Michael K Hancock Malene Hansen Hisashi Harada Masaru Harada Stefan E Hardt J Wade Harper Adrian L Harris James Harris Steven D Harris Makoto Hashimoto Jeffrey A Haspel Shin-ichiro Hayashi Lori A Hazelhurst Congcong He You-Wen He Marie-Joseé Hébert Kim A Heidenreich Miep H Helfrich Gudmundur V Helgason Elizabeth P Henske Brian Herman Paul K Herman Claudio Hetz Sabine Hilfiker Joseph A Hill Lynne J Hocking Paul Hofman Thomas G Hofmann Jörg Höhfeld Tessa L Holyoake Ming-Huang Hong David A Hood Gökhan S Hotamisligil Ewout J Houwerzijl Maria Høyer-Hansen Bingren Hu Chien-An A Hu Hong-Ming Hu Ya Hua Canhua Huang Ju Huang Shengbing Huang Wei-Pang Huang Tobias B Huber Won-Ki Huh Tai-Ho Hung Ted R Hupp Gang Min Hur James B Hurley Sabah N A Hussain Patrick J Hussey Jung Jin Hwang Seungmin Hwang Atsuhiro Ichihara Shirin Ilkhanizadeh Ken Inoki Takeshi Into Valentina Iovane Juan L Iovanna Nancy Y Ip Yoshitaka Isaka Hiroyuki Ishida Ciro Isidoro Ken-ichi Isobe Akiko Iwasaki Marta Izquierdo Yotaro Izumi Panu M Jaakkola Marja Jäättelä George R Jackson William T Jackson Bassam Janji Marina Jendrach Ju-Hong Jeon Eui-Bae Jeung Hong Jiang Hongchi Jiang Jean X Jiang Ming Jiang Qing Jiang Xuejun Jiang Xuejun Jiang Alberto Jiménez Meiyan Jin Shengkan Jin Cheol O Joe Terje Johansen Daniel E Johnson Gail V W Johnson Nicola L Jones Bertrand Joseph Suresh K Joseph Annie M Joubert Gábor Juhász Lucienne Juillerat-Jeanneret Chang Hwa Jung Yong-Keun Jung Kai Kaarniranta Allen Kaasik Tomohiro Kabuta Motoni Kadowaki Katarina Kagedal Yoshiaki Kamada Vitaliy O Kaminskyy Harm H Kampinga Hiromitsu Kanamori Chanhee Kang Khong Bee Kang Kwang Il Kang Rui Kang Yoon-A Kang Tomotake Kanki Thirumala-Devi Kanneganti Haruo Kanno Anumantha G Kanthasamy Arthi Kanthasamy Vassiliki Karantza Gur P Kaushal Susmita Kaushik Yoshinori Kawazoe Po-Yuan Ke John H Kehrl Ameeta Kelekar Claus Kerkhoff David H Kessel Hany Khalil Jan A K W Kiel Amy A Kiger Akio Kihara Deok Ryong Kim Do-Hyung Kim Dong-Hou Kim Eun-Kyoung Kim Hyung-Ryong Kim Jae-Sung Kim Jeong Hun Kim Jin Cheon Kim John K Kim Peter K Kim Seong Who Kim Yong-Sun Kim Yonghyun Kim Adi Kimchi Alec C Kimmelman Jason S King Timothy J Kinsella Vladimir Kirkin Lorrie A Kirshenbaum Katsuhiko Kitamoto Kaio Kitazato Ludger Klein Walter T Klimecki Jochen Klucken Erwin Knecht Ben C B Ko Jan C Koch Hiroshi Koga Jae-Young Koh Young Ho Koh Masato Koike Masaaki Komatsu Eiki Kominami Hee Jeong Kong Wei-Jia Kong Viktor I Korolchuk Yaichiro Kotake Michael I Koukourakis Juan B Kouri Flores Attila L Kovács Claudine Kraft Dimitri Krainc Helmut Krämer Carole Kretz-Remy Anna M Krichevsky Guido Kroemer Rejko Krüger Oleg Krut Nicholas T Ktistakis Chia-Yi Kuan Roza Kucharczyk Ashok Kumar Raj Kumar Sharad Kumar Mondira Kundu Hsing-Jien Kung Tino Kurz Ho Jeong Kwon Albert R La Spada Frank Lafont Trond Lamark Jacques Landry Jon D Lane Pierre Lapaquette Jocelyn F Laporte Lajos László Sergio Lavandero Josée N Lavoie Robert Layfield Pedro A Lazo Weidong Le Laurent Le Cam Daniel J Ledbetter Alvin J X Lee Byung-Wan Lee Gyun Min Lee Jongdae Lee Ju-Hyun Lee Michael Lee Myung-Shik Lee Sug Hyung Lee Christiaan Leeuwenburgh Patrick Legembre Renaud Legouis Michael Lehmann Huan-Yao Lei Qun-Ying Lei David A Leib José Leiro John J Lemasters Antoinette Lemoine Maciej S Lesniak Dina Lev Victor V Levenson Beth Levine Efrat Levy Faqiang Li Jun-Lin Li Lian Li Sheng Li Weijie Li Xue-Jun Li Yan-bo Li Yi-Ping Li Chengyu Liang Qiangrong Liang Yung-Feng Liao Pawel P Liberski Andrew Lieberman Hyunjung J Lim Kah-Leong Lim Kyu Lim Chiou-Feng Lin Fu-Cheng Lin Jian Lin Jiandie D Lin Kui Lin Wan-Wan Lin Weei-Chin Lin Yi-Ling Lin Rafael Linden Paul Lingor Jennifer Lippincott-Schwartz Michael P Lisanti Paloma B Liton Bo Liu Chun-Feng Liu Kaiyu Liu Leyuan Liu Qiong A Liu Wei Liu Young-Chau Liu Yule Liu Richard A Lockshin Chun-Nam Lok Sagar Lonial Benjamin Loos Gabriel Lopez-Berestein Carlos López-Otín Laura Lossi Michael T Lotze Peter Lőw Binfeng Lu Bingwei Lu Bo Lu Zhen Lu Frédéric Luciano Nicholas W Lukacs Anders H Lund Melinda A Lynch-Day Yong Ma Fernando Macian Jeff P MacKeigan Kay F Macleod Frank Madeo Luigi Maiuri Maria Chiara Maiuri Davide Malagoli May Christine V Malicdan Walter Malorni Na Man Eva-Maria Mandelkow Stéphen Manon Irena Manov Kai Mao Xiang Mao Zixu Mao Philippe Marambaud Daniela Marazziti Yves L Marcel Katie Marchbank Piero Marchetti Stefan J Marciniak Mateus Marcondes Mohsen Mardi Gabriella Marfe Guillermo Mariño Maria Markaki Mark R Marten Seamus J Martin Camille Martinand-Mari Wim Martinet Marta Martinez-Vicente Matilde Masini Paola Matarrese Saburo Matsuo Raffaele Matteoni Andreas Mayer Nathalie M Mazure David J McConkey Melanie J McConnell Catherine McDermott Christine McDonald Gerald M McInerney Sharon L McKenna BethAnn McLaughlin Pamela J McLean Christopher R McMaster G Angus McQuibban Alfred J Meijer Miriam H Meisler Alicia Meléndez Thomas J Melia Gerry Melino Maria A Mena Javier A Menendez Rubem F S Menna-Barreto Manoj B Menon Fiona M Menzies Carol A Mercer Adalberto Merighi Diane E Merry Stefania Meschini Christian G Meyer Thomas F Meyer Chao-Yu Miao Jun-Ying Miao Paul A M Michels Carine Michiels Dalibor Mijaljica Ana Milojkovic Saverio Minucci Clelia Miracco Cindy K Miranti Ioannis Mitroulis Keisuke Miyazawa Noboru Mizushima Baharia Mograbi Simin Mohseni Xavier Molero Bertrand Mollereau Faustino Mollinedo Takashi Momoi Iryna Monastyrska Martha M Monick Mervyn J Monteiro Michael N Moore Rodrigo Mora Kevin Moreau Paula I Moreira Yuji Moriyasu Jorge Moscat Serge Mostowy Jeremy C Mottram Tomasz Motyl Charbel E-H Moussa Sylke Müller Sylviane Muller Karl Münger Christian Münz Leon O Murphy Maureen E Murphy Antonio Musarò Indira Mysorekar Eiichiro Nagata Kazuhiro Nagata Aimable Nahimana Usha Nair Toshiyuki Nakagawa Kiichi Nakahira Hiroyasu Nakano Hitoshi Nakatogawa Meera Nanjundan Naweed I Naqvi Derek P Narendra Masashi Narita Miguel Navarro Steffan T Nawrocki Taras Y Nazarko Andriy Nemchenko Mihai G Netea Thomas P Neufeld Paul A Ney Ioannis P Nezis Huu Phuc Nguyen Daotai Nie Ichizo Nishino Corey Nislow Ralph A Nixon Takeshi Noda Angelika A Noegel Anna Nogalska Satoru Noguchi Lucia Notterpek Ivana Novak Tomoyoshi Nozaki Nobuyuki Nukina Thorsten Nürnberger Beat Nyfeler Keisuke Obara Terry D Oberley Salvatore Oddo Michinaga Ogawa Toya Ohashi Koji Okamoto Nancy L Oleinick F Javier Oliver Laura J Olsen Stefan Olsson Onya Opota Timothy F Osborne Gary K Ostrander Kinya Otsu Jing-hsiung James Ou Mireille Ouimet Michael Overholtzer Bulent Ozpolat Paolo Paganetti Ugo Pagnini Nicolas Pallet Glen E Palmer Camilla Palumbo Tianhong Pan 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Ravikumar Swapan K Ray Bruce H Reed John C Reed Fulvio Reggiori Anne Régnier-Vigouroux Andreas S Reichert John J Reiners Russel J Reiter Jun Ren José L Revuelta Christopher J Rhodes Konstantinos Ritis Elizete Rizzo Jeffrey Robbins Michel Roberge Hernan Roca Maria C Roccheri Stephane Rocchi H Peter Rodemann Santiago Rodríguez de Córdoba Bärbel Rohrer Igor B Roninson Kirill Rosen Magdalena M Rost-Roszkowska Mustapha Rouis Kasper M A Rouschop Francesca Rovetta Brian P Rubin David C Rubinsztein Klaus Ruckdeschel Edmund B Rucker Assaf Rudich Emil Rudolf Nelson Ruiz-Opazo Rossella Russo Tor Erik Rusten Kevin M Ryan Stefan W Ryter David M Sabatini Junichi Sadoshima Tapas Saha Tatsuya Saitoh Hiroshi Sakagami Yasuyoshi Sakai Ghasem Hoseini Salekdeh Paolo Salomoni Paul M Salvaterra Guy Salvesen Rosa Salvioli Anthony M J Sanchez José A Sánchez-Alcázar Ricardo Sánchez-Prieto Marco Sandri Uma Sankar Poonam Sansanwal Laura Santambrogio Shweta Saran Sovan Sarkar Minnie Sarwal Chihiro Sasakawa Ausra Sasnauskiene Miklós Sass Ken Sato Miyuki Sato Anthony H V Schapira Michael Scharl Hermann M Schätzl Wiep Scheper Stefano Schiaffino Claudio Schneider Marion E Schneider Regine Schneider-Stock Patricia V Schoenlein Daniel F Schorderet Christoph Schüller Gary K Schwartz Luca Scorrano Linda Sealy Per O Seglen Juan Segura-Aguilar Iban Seiliez Oleksandr Seleverstov Christian Sell Jong Bok Seo Duska Separovic Vijayasaradhi Setaluri Takao Setoguchi Carmine Settembre John J Shacka Mala Shanmugam Irving M Shapiro Eitan Shaulian Reuben J Shaw James H Shelhamer Han-Ming Shen Wei-Chiang Shen Zu-Hang Sheng Yang Shi Kenichi Shibuya Yoshihiro Shidoji Jeng-Jer Shieh Chwen-Ming Shih Yohta Shimada Shigeomi Shimizu Takahiro Shintani Orian S Shirihai Gordon C Shore Andriy A Sibirny Stan B Sidhu Beata Sikorska Elaine C M Silva-Zacarin Alison Simmons Anna Katharina Simon Hans-Uwe Simon Cristiano Simone Anne Simonsen David A Sinclair Rajat Singh Debasish Sinha Frank A Sinicrope Agnieszka Sirko Parco M Siu Efthimios Sivridis Vojtech Skop Vladimir P Skulachev Ruth S Slack Soraya S Smaili Duncan R Smith Maria S Soengas Thierry Soldati Xueqin Song Anil K Sood Tuck Wah Soong Federica Sotgia Stephen A Spector Claudia D Spies Wolfdieter Springer Srinivasa M Srinivasula Leonidas Stefanis Joan S Steffan Ruediger Stendel Harald Stenmark Anastasis Stephanou Stephan T Stern Cinthya Sternberg Björn Stork Peter Strålfors Carlos S Subauste Xinbing Sui David Sulzer Jiaren Sun Shi-Yong Sun Zhi-Jun Sun Joseph J Y Sung Kuninori Suzuki Toshihiko Suzuki Michele S Swanson Charles Swanton Sean T Sweeney Lai-King Sy Gyorgy Szabadkai Ira Tabas Heinrich Taegtmeyer Marco Tafani Krisztina Takács-Vellai Yoshitaka Takano Kaoru Takegawa Genzou Takemura Fumihiko Takeshita Nicholas J Talbot Kevin S W Tan Keiji Tanaka Kozo Tanaka Daolin Tang Dingzhong Tang Isei Tanida Bakhos A Tannous Nektarios Tavernarakis Graham S Taylor Gregory A Taylor J Paul Taylor Lance S Terada Alexei Terman Gianluca Tettamanti Karin Thevissen Craig B Thompson Andrew Thorburn Michael Thumm FengFeng Tian Yuan Tian Glauco Tocchini-Valentini Aviva M Tolkovsky Yasuhiko Tomino Lars Tönges Sharon A Tooze Cathy Tournier John Tower Roberto Towns Vladimir Trajkovic Leonardo H Travassos Ting-Fen Tsai Mario P Tschan Takeshi Tsubata Allan Tsung Boris Turk Lorianne S Turner Suresh C Tyagi Yasuo Uchiyama Takashi Ueno Midori Umekawa Rika Umemiya-Shirafuji Vivek K Unni Maria I Vaccaro Enza Maria Valente Greet Van den Berghe Ida J van der Klei Wouter van Doorn Linda F van Dyk Marjolein van Egmond Leo A van Grunsven Peter Vandenabeele Wim P Vandenberghe Ilse Vanhorebeek Eva C Vaquero Guillermo Velasco Tibor Vellai Jose Miguel Vicencio Richard D Vierstra Miquel Vila Cécile Vindis Giampietro Viola Maria Teresa Viscomi Olga V Voitsekhovskaja Clarissa von Haefen Marcela Votruba Keiji Wada Richard Wade-Martins Cheryl L Walker Craig M Walsh Jochen Walter Xiang-Bo Wan Aimin Wang Chenguang Wang Dawei Wang Fan Wang Fen Wang Guanghui Wang Haichao Wang Hong-Gang Wang Horng-Dar Wang Jin Wang Ke Wang Mei Wang Richard C Wang Xinglong Wang Xuejun Wang Ying-Jan Wang Yipeng Wang Zhen Wang Zhigang Charles Wang Zhinong Wang Derick G Wansink Diane M Ward Hirotaka Watada Sarah L Waters Paul Webster Lixin Wei Conrad C Weihl William A Weiss Scott M Welford Long-Ping Wen Caroline A Whitehouse J Lindsay Whitton Alexander J Whitworth Tom Wileman John W Wiley Simon Wilkinson Dieter Willbold Roger L Williams Peter R Williamson Bradly G Wouters Chenghan Wu Dao-Cheng Wu William K K Wu Andreas Wyttenbach Ramnik J Xavier Zhijun Xi Pu Xia Gengfu Xiao Zhiping Xie Zhonglin Xie Da-zhi Xu Jianzhen Xu Liang Xu Xiaolei Xu Ai Yamamoto Akitsugu Yamamoto Shunhei Yamashina Michiaki Yamashita Xianghua Yan Mitsuhiro Yanagida Dun-Sheng Yang Elizabeth Yang Jin-Ming Yang Shi Yu Yang Wannian Yang Wei Yuan Yang Zhifen Yang Meng-Chao Yao Tso-Pang Yao Behzad Yeganeh Wei-Lien Yen Jia-jing Yin Xiao-Ming Yin Ook-Joon Yoo Gyesoon Yoon Seung-Yong Yoon Tomohiro Yorimitsu Yuko Yoshikawa Tamotsu Yoshimori Kohki Yoshimoto Ho Jin You Richard J Youle Anas Younes Li Yu Long Yu Seong-Woon Yu Wai Haung Yu Zhi-Min Yuan Zhenyu Yue Cheol-Heui Yun Michisuke Yuzaki Olga Zabirnyk Elaine Silva-Zacarin David Zacks Eldad Zacksenhaus Nadia Zaffaroni Zahra Zakeri Herbert J Zeh Scott O Zeitlin Hong Zhang Hui-Ling Zhang Jianhua Zhang Jing-Pu Zhang Lin Zhang Long Zhang Ming-Yong Zhang Xu Dong Zhang Mantong Zhao Yi-Fang Zhao Ying Zhao Zhizhuang J Zhao Xiaoxiang Zheng Boris Zhivotovsky Qing Zhong Cong-Zhao Zhou Changlian Zhu Wei-Guo Zhu Xiao-Feng Zhu Xiongwei Zhu Yuangang Zhu Teresa Zoladek Wei-Xing Zong Antonio Zorzano Jürgen Zschocke Brian Zuckerbraun

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http://dx.doi.org/10.1016/j.bbrc.2010.07.025DOI Listing
August 2010

Terpestacin inhibits tumor angiogenesis by targeting UQCRB of mitochondrial complex III and suppressing hypoxia-induced reactive oxygen species production and cellular oxygen sensing.

J Biol Chem 2010 Apr 9;285(15):11584-95. Epub 2010 Feb 9.

Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857036PMC
April 2010

Autophagonizer, a novel synthetic small molecule, induces autophagic cell death.

Biochem Biophys Res Commun 2010 Mar 18;393(4):849-54. Epub 2010 Feb 18.

Chemical Genomics Laboratory, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2010.02.097DOI Listing
March 2010

NBBA, a synthetic small molecule, inhibits TNF-alpha-induced angiogenesis by suppressing the NF-kappaB signaling pathway.

Biochem Biophys Res Commun 2010 Jan 24;391(3):1500-5. Epub 2009 Dec 24.

Chemical Genomics Laboratory, Department of Biotechnology, Translational Research Center for Protein Function Control, College of Life Science and Biotechnology, Yonsei University, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2009.12.101DOI Listing
January 2010

The effect of xanthorrhizol on the expression of matrix metalloproteinase-1 and type-I procollagen in ultraviolet-irradiated human skin fibroblasts.

Phytother Res 2009 Sep;23(9):1299-302

Department of Biotechnology, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749, Republic of Korea.

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http://doi.wiley.com/10.1002/ptr.2768
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September 2009

N-hydroxy-7-(2-naphthylthio) heptanomide inhibits retinal and choroidal angiogenesis.

Mol Pharm 2009 Mar-Apr;6(2):513-9

Chemical Genomics Laboratory, Department of Biotechnology, College of Life Science & Biotechnology, Yonsei University, Seoul 120-749, Korea.

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http://dx.doi.org/10.1021/mp800178bDOI Listing
September 2009

Overexpression of metastasis-associated protein 2 is associated with hepatocellular carcinoma size and differentiation.

J Gastroenterol Hepatol 2009 Aug;24(8):1445-50

NeuroVascular Coordination Research Center, College of Pharmacy, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1111/j.1440-1746.2009.05965.xDOI Listing
August 2009

Identification and validation of calmodulin as a binding protein of an anti-proliferative small molecule 3,4-dihydroisoquinolinium salt.

Proteomics Clin Appl 2009 Apr 9;3(4):423-32. Epub 2009 Mar 9.

Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul, Korea.

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http://dx.doi.org/10.1002/prca.200800060DOI Listing
April 2009

Hydroxamic acid derivatives of mycophenolic acid inhibit histone deacetylase at the cellular level.

Biosci Biotechnol Biochem 2008 Oct 7;72(10):2623-31. Epub 2008 Oct 7.

Research Faculty of Agriculture, Hokkaido University, Sapporo, Japan.

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http://dx.doi.org/10.1271/bbb.80303DOI Listing
October 2008

The non-provitamin A carotenoid, lutein, inhibits NF-kappaB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/Akt and NF-kappaB-inducing kinase pathways: role of H(2)O(2) in NF-kappaB activation.

Free Radic Biol Med 2008 Sep 27;45(6):885-96. Epub 2008 Jun 27.

Vascular System Research Center and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chunchon, Kangwon-do 200-701, Korea.

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http://dx.doi.org/10.1016/j.freeradbiomed.2008.06.019DOI Listing
September 2008

Streptopyrrolidine, an angiogenesis inhibitor from a marine-derived Streptomyces sp. KORDI-3973.

Phytochemistry 2008 Sep 21;69(12):2363-6. Epub 2008 Jul 21.

Marine Natural Products Laboratory, Korea Ocean Research & Development Institute, Ansan P.O. Box 29, Seoul 425-600, Republic of Korea.

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http://dx.doi.org/10.1016/j.phytochem.2008.05.020DOI Listing
September 2008

Hot springs and cool natural products.

Nat Chem Biol 2008 Aug;4(8):444-6

Chemical Genomics Laboratory, Department of Biotechnology, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749, Korea.

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http://www.nature.com/articles/nchembio0808-444
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August 2008

Global and focused transcriptional profiling of small molecule aminopeptidase N inhibitor reveals its mechanism of angiogenesis inhibition.

Biochem Biophys Res Commun 2008 Jun 14;371(1):99-103. Epub 2008 Apr 14.

Chemical Genomics Laboratory, Department of Biotechnology, College of Life Science & Biotechnology, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2008.04.023DOI Listing
June 2008

Inhibition of histone deacetylase1 induces autophagy.

Biochem Biophys Res Commun 2008 May 13;369(4):1179-83. Epub 2008 Mar 13.

Chemical Genomics Laboratory, Department of Biotechnology, Yonsei Biomedical Science and Technology Initiative, College of Life Science & Biotechnology, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2008.03.019DOI Listing
May 2008

Molecular mechanism of ADP-ribosyl cyclase activation in angiotensin II signaling in murine mesangial cells.

Am J Physiol Renal Physiol 2008 Apr 13;294(4):F982-9. Epub 2008 Feb 13.

Dept. of Biochemistry, Chonbuk National Univ. Medical School, Keum-am dong, Jeonju, 561-182, Republic of Korea.

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http://dx.doi.org/10.1152/ajprenal.00483.2007DOI Listing
April 2008

Inhibition of choroidal neovascularization by homoisoflavanone, a new angiogenesis inhibitor.

Mol Vis 2008 Mar 18;14:556-61. Epub 2008 Mar 18.

Department of Ophthalmology, College of Medicine, Seoul National University, Seoul Artificial Eye Center Clinical ResearchInstitute, Seoul National University Hospital, Seoul, Korea.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2274926PMC
March 2008

Potent inhibition of in vivo angiogenesis and tumor growth by a novel cyclooxygenase-2 inhibitor, enoic acanthoic acid.

Cancer Sci 2007 Dec 19;98(12):1943-8. Epub 2007 Sep 19.

Department of Biotechnology, College of Engineering, Yonsei University, 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749, Korea.

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http://dx.doi.org/10.1111/j.1349-7006.2007.00617.xDOI Listing
December 2007

Proteomic analysis of microvesicles derived from human colorectal cancer cells.

J Proteome Res 2007 Dec 24;6(12):4646-55. Epub 2007 Oct 24.

Department of Life Science and Division of Molecular and Life Sciences, Pohang University of Science and Technology, Pohang 790-784, Republic of Korea.

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http://dx.doi.org/10.1021/pr070192yDOI Listing
December 2007

Functional analysis of a histone deacetylase-like protein of Thermus caldophilus GK24 in mammalian cell.

Biochem Biophys Res Commun 2007 Nov 28;362(4):995-1000. Epub 2007 Aug 28.

Chemical Genomics Laboratory, Department of Biotechnology, College of Engineering, Yonsei University, Seoul 120-749, Republic of Korea.

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November 2007

Homoisoflavanone inhibits retinal neovascularization through cell cycle arrest with decrease of cdc2 expression.

Biochem Biophys Res Commun 2007 Nov 28;362(4):848-52. Epub 2007 Aug 28.

Department of Ophthalmology, College of Medicine, Seoul National University, and Seoul Artificial Eye Center Clinical Research Institute, Seoul National University Hospital, Seoul 110-744, Republic of Korea.

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November 2007

Aminopeptidase N/CD13 induces angiogenesis through interaction with a pro-angiogenic protein, galectin-3.

Biochem Biophys Res Commun 2007 Nov 7;363(2):336-41. Epub 2007 Sep 7.

Chemical Genomics Laboratory, Department of Biotechnology, College of Engineering, Yonsei University, 134 Shinchon-Dong, Seodaemun-Gu, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2007.08.179DOI Listing
November 2007

Cloning, expression, and biochemical characterization of a new histone deacetylase-like protein from Thermus caldophilus GK24.

Biochem Biophys Res Commun 2007 Sep 9;361(1):55-61. Epub 2007 Jul 9.

Chemical Genomics Laboratory, Department of Biotechnology, College of Engineering, Yonsei University, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2007.06.147DOI Listing
September 2007

Water extract of Korean red ginseng stimulates angiogenesis by activating the PI3K/Akt-dependent ERK1/2 and eNOS pathways in human umbilical vein endothelial cells.

Biol Pharm Bull 2007 Sep;30(9):1674-9

Vascular System Research Center and Department of Molecular and Cellular Biochemistry, School of Medicine, Kangwon National University, Chunchon, Kangwon-do 200-701, Korea.

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http://dx.doi.org/10.1248/bpb.30.1674DOI Listing
September 2007

Development of a new Ca2+/calmodulin antagonist and its anti-proliferative activity against colorectal cancer cells.

Biochem Biophys Res Commun 2007 Aug 4;359(3):747-51. Epub 2007 Jun 4.

Chemical Genomics Laboratory, Department of Biotechnology, College of Engineering, Yonsei University, Seoul 120-749, Republic of Korea.

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http://dx.doi.org/10.1016/j.bbrc.2007.05.174DOI Listing
August 2007

Streptochlorin, a marine natural product, inhibits NF-kappaB activation and suppresses angiogenesis in vitro.

J Microbiol Biotechnol 2007 Aug;17(8):1338-43

Chemical Genomics Laboratory, Department of Biotechnology, College of Engineering, Yonsei University, Seoul 120-749, Korea.

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August 2007

Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110.

J Microbiol Biotechnol 2007 Aug;17(8):1403-6

Marine Natural Products Laboratory, Korea Ocean Research & Development Institute, Ansan, P O. Box 29, Seoul 425-600, Korea.

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August 2007

Synthesis and biological activity of fungal metabolite, 4-hydroxy-3-(3'-methyl-2'-butenyl)-benzoic acid.

J Microbiol Biotechnol 2007 Mar;17(3):543-5

Chemical Genomics Laboratory, Department of Biotechnology, College ofEngineering, Yonsei University, Seoul 120-749, Korea.

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March 2007