Hitoshi Okochi

Hitoshi Okochi

UNVERIFIED PROFILE

Are you Hitoshi Okochi?   Register this Author

Register author
Hitoshi Okochi

Hitoshi Okochi

Publications by authors named "Hitoshi Okochi"

Are you Hitoshi Okochi?   Register this Author

70Publications

702Reads

38Profile Views

The intraperitoneal space is more favorable than the subcutaneous one for transplanting alginate fiber containing iPS-derived islet-like cells.

Regen Ther 2019 Dec 29;11:65-72. Epub 2019 May 29.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama Shinjuku-ku, Tokyo, 162-8655, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.reth.2019.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6543182PMC
December 2019

Endodermal differentiation of human induced pluripotent stem cells using simple dialysis culture system in suspension culture.

Regen Ther 2019 Dec 30;12:14-19. Epub 2019 May 30.

Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8505, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.reth.2019.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6933453PMC
December 2019

Establishment of a diabetes mellitus type 1 model in the common marmoset.

Sci Rep 2019 Oct 10;9(1):14546. Epub 2019 Oct 10.

Department of Pancreatic Islet Cell Transplantation, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-019-51199-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6787219PMC
October 2019

Facile fabrication of PEG-coated PLGA microspheres via SPG membrane emulsification for the treatment of scleroderma by ECM degrading enzymes.

Colloids Surf B Biointerfaces 2019 Jul 14;179:453-461. Epub 2019 Apr 14.

Center for Disease Biology and Integrative Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan; Department of Bioengineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09277765193025
Publisher Site
http://dx.doi.org/10.1016/j.colsurfb.2019.04.028DOI Listing
July 2019

Induction of functional islet-like cells from human iPS cells by suspension culture.

Regen Ther 2019 Jun 2;10:69-76. Epub 2019 Jan 2.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.reth.2018.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317273PMC
June 2019

Expression of mutant mRNA and protein in pancreatic cells derived from MODY3- iPS cells.

PLoS One 2019 30;14(5):e0217110. Epub 2019 May 30.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0217110PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542550PMC
May 2019

Definitive endoderm differentiation is promoted in suspension cultured human iPS-derived spheroids more than in adherent cells.

Int J Dev Biol 2019 ;63(6-7):271-280

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1387/ijdb.180251syDOI Listing
January 2019

Characterization of Peribiliary Gland-Constituting Cells Based on Differential Expression of Trophoblast Cell Surface Protein 2 in Biliary Tract.

Am J Pathol 2018 09 3;188(9):2059-2073. Epub 2018 Jul 3.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan; Laboratory of Stem Cell Regulation, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2018.05.016DOI Listing
September 2018

Introduction of the TERT and BMI1 genes into murine dermal papilla cells ameliorates hair inductive activity.

J Dermatol Sci 2018 May 21;90(2):218-221. Epub 2018 Feb 21.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama Shinjuku-ku, Tokyo, 162-8655, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdermsci.2018.02.003DOI Listing
May 2018

Oncostatin M causes liver fibrosis by regulating cooperation between hepatic stellate cells and macrophages in mice.

Hepatology 2018 01 15;67(1):296-312. Epub 2017 Nov 15.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.29421DOI Listing
January 2018

Suppressive Effects of Mesenchymal Stem Cells in Adipose Tissue on Allergic Contact Dermatitis.

Ann Dermatol 2017 Aug 21;29(4):391-399. Epub 2017 Jun 21.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5021/ad.2017.29.4.391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500702PMC
August 2017

Efficient generation of functional pancreatic β-cells from human induced pluripotent stem cells.

J Diabetes 2017 Feb 31;9(2):168-179. Epub 2016 May 31.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1753-0407.12400DOI Listing
February 2017

Establishment of maturity-onset diabetes of the young-induced pluripotent stem cells from a Japanese patient.

J Diabetes Investig 2015 Sep 5;6(5):543-7. Epub 2015 Mar 5.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jdi.12334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578493PMC
September 2015

Synergistic effect of PDGF and FGF2 for cell proliferation and hair inductive activity in murine vibrissal dermal papilla in vitro.

J Dermatol Sci 2015 Aug 27;79(2):110-8. Epub 2015 Apr 27.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, Japan. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09231811150015
Publisher Site
http://dx.doi.org/10.1016/j.jdermsci.2015.04.007DOI Listing
August 2015

Lymphatic dysfunction attenuates tumor immunity through impaired antigen presentation.

Oncotarget 2015 Jul;6(20):18081-93

Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627236PMC
http://dx.doi.org/10.18632/oncotarget.4018DOI Listing
July 2015

Safety assessment of bone marrow derived MSC grown in platelet-rich plasma.

Regen Ther 2015 Jun 23;1:72-79. Epub 2015 Mar 23.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.reth.2015.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581768PMC
June 2015

Case series of patients with chronic foot ulcers treated with autologous platelet-rich plasma.

J Dermatol 2015 Mar 23;42(3):288-95. Epub 2015 Jan 23.

Department of Dermatology, National Center for Global Health and Medicine, Tokyo, Japan; Department of Dermatology, National Suruga Sanatorium, Shizuoka, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1346-8138.12777DOI Listing
March 2015

Cilostazol improves lymphatic function by inducing proliferation and stabilization of lymphatic endothelial cells.

J Dermatol Sci 2014 May 21;74(2):150-8. Epub 2014 Jan 21.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09231811140000
Publisher Site
http://dx.doi.org/10.1016/j.jdermsci.2014.01.001DOI Listing
May 2014

Delayed wound healing due to increased interleukin-10 expression in mice with lymphatic dysfunction.

J Leukoc Biol 2013 Jul 6;94(1):137-45. Epub 2013 May 6.

Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0812408DOI Listing
July 2013

CXCR3 deficiency prolongs Th1-type contact hypersensitivity.

J Immunol 2013 Jun 8;190(12):6059-70. Epub 2013 May 8.

Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo 113-8655, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1201606DOI Listing
June 2013

Blocking MAPK signaling downregulates CCL21 in lymphatic endothelial cells and impairs contact hypersensitivity responses.

J Invest Dermatol 2011 Sep 19;131(9):1927-35. Epub 2011 May 19.

Department of Dermatology, Faculty of Medicine, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/jid.2011.135DOI Listing
September 2011

Intracellular reactivation of transcription factors fused with protein transduction domain.

J Biotechnol 2011 Jul 23;154(4):298-303. Epub 2011 May 23.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jbiotec.2011.05.006DOI Listing
July 2011

Efficient myogenic differentiation of murine dermal Sca-1 (−) cells via initial aggregation culture.

Tissue Eng Part A 2010 Oct;16(10):3251-9

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/ten.TEA.2009.0678DOI Listing
October 2010

Efficiently differentiating vascular endothelial cells from adipose tissue-derived mesenchymal stem cells in serum-free culture.

Biochem Biophys Res Commun 2010 Oct 12;400(4):461-5. Epub 2010 Aug 12.

Department of Regenerative Medicine, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0006291X100151
Publisher Site
http://dx.doi.org/10.1016/j.bbrc.2010.08.029DOI Listing
October 2010

Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure.

J Gastroenterol Hepatol 2009 Jan 25;24(1):70-7. Epub 2008 Jun 25.

Section for Studies on Metastasis, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1440-1746.2008.05496.x
Publisher Site
http://dx.doi.org/10.1111/j.1440-1746.2008.05496.xDOI Listing
January 2009

Serum levels of IgE anti-BP180 and anti-BP230 autoantibodies in patients with bullous pemphigoid.

J Dermatol Sci 2008 Feb 24;49(2):153-61. Epub 2007 Oct 24.

Department of Dermatology, Graduate School of Medicine, University of Tokyo, Bunkyo, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdermsci.2007.08.008DOI Listing
February 2008

Role of IRS and PHIP on insulin-induced tyrosine phosphorylation and distribution of IRS proteins.

Cell Struct Funct 2007 13;32(1):69-78. Epub 2007 Jul 13.

Department of Metabolic Disorder, Research Institute, International Medical Center of Japan, Toyama, Shinjuku-ku, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1247/csf.07003DOI Listing
October 2007

The involvement of Gab1 and PI 3-kinase in beta1 integrin signaling in keratinocytes.

Biochem Biophys Res Commun 2007 Sep 16;361(1):224-9. Epub 2007 Jul 16.

Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0006291X0701479
Publisher Site
http://dx.doi.org/10.1016/j.bbrc.2007.07.017DOI Listing
September 2007

Adipose tissue-derived mesenchymal stem cells as a source of human hepatocytes.

Hepatology 2007 Jul;46(1):219-28

Section for Studies on Metastasis, National Cancer Center Research Institute 1-1, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.21704DOI Listing
July 2007

Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells.

Nat Cell Biol 2007 Jun 21;9(6):625-35. Epub 2007 May 21.

Laboratory for Pluripotent Cell Studies, RIKEN Center for Developmental Biology, Minatojima-minamimachi 2-2-3, Chu-o-ku, Kobe, Hyogo 650-0047, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb1589DOI Listing
June 2007

Isolation of murine hair-inducing cells using the cell surface marker prominin-1/CD133.

J Invest Dermatol 2007 May 21;127(5):1052-60. Epub 2006 Dec 21.

Department of Tissue Regeneration, Research Institute, International Medical Center of Japan, Toyama, Shinjuku, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0022202X1533374
Publisher Site
http://dx.doi.org/10.1038/sj.jid.5700665DOI Listing
May 2007

Long-term culture of mouse vibrissal dermal papilla cells and de novo hair follicle induction.

Tissue Eng 2007 May;13(5):975-82

Department of Tissue Regeneration, Research Institute, International Medical Center of Japan, Shinjuku-ku, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/ten.2006.0304DOI Listing
May 2007

Pancreatic tissue formation from murine embryonic stem cells in vitro.

Differentiation 2007 Jan;75(1):1-11

Department of Life Science (Biology), Graduate School of Arts & Science, University of Tokyo, Meguro, Tokyo 153-8902, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1432-0436.2006.00109.xDOI Listing
January 2007

N-cadherin is a useful marker for the progenitor of cardiomyocytes differentiated from mouse ES cells in serum-free condition.

Biochem Biophys Res Commun 2006 Dec 2;351(4):877-82. Epub 2006 Nov 2.

Department of Biological Sciences, Graduate School of Sciences, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2006.10.126DOI Listing
December 2006

Ciliated cells differentiated from mouse embryonic stem cells.

Stem Cells 2006 May 12;24(5):1381-8. Epub 2006 Jan 12.

Department of Biological Science, The University of Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/stemcells.2005-0464DOI Listing
May 2006

Activation of Akt by mechanical stretching in human epidermal keratinocytes.

Exp Dermatol 2006 May;15(5):356-61

Department of Dermatology, University of Tokyo, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.0906-6705.2006.00425.xDOI Listing
May 2006

Properties of growth and molecular profiles of rat progenitor cells from ciliary epithelium.

Exp Eye Res 2006 Mar 29;82(3):471-8. Epub 2005 Sep 29.

Department of Regenerative Medicine, Research Institute, International Medical Center of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S001448350500247
Publisher Site
http://dx.doi.org/10.1016/j.exer.2005.08.005DOI Listing
March 2006

Epithelioid sarcoma associated with lung adenocarcinoma.

J Dermatol 2005 Nov;32(11):904-8

Department of Dermatology, Faculty of Medicine, University of Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1346-8138.2005.tb00869.xDOI Listing
November 2005

Clonogenic analysis of ciliary epithelial derived retinal progenitor cells in rabbits.

Exp Eye Res 2005 Oct;81(4):437-45

Department of Regenerative Medicine, Research Institute, International Medical Center of Japan, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exer.2005.03.003DOI Listing
October 2005

Leukemia inhibitory factor as an anti-apoptotic mitogen for pluripotent mouse embryonic stem cells in a serum-free medium without feeder cells.

In Vitro Cell Dev Biol Anim 2005 Jan-Feb;41(1-2):19-28

Department of Biochemistry and Molecular Biology, Kanagawa Dental College, Yokosuka 238-8580, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1290/0502010.1DOI Listing
October 2005

Characterization and localization of side population cells in mouse skin.

Stem Cells 2005 Jun-Jul;23(6):834-41

Department of Regenerative Medicine, Research Institute, International Medical Center of Japan, 1-21-1 Toyama, Tokyo 162-8655, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/stemcells.2004-0226DOI Listing
September 2005

Insulin-induced cell cycle progression is impaired in chinese hamster ovary cells overexpressing insulin receptor substrate-3.

Endocrinology 2004 Dec 26;145(12):5862-74. Epub 2004 Aug 26.

Department of Metabolic Disorder, Research Institute, International Medical Center of Japan, Shinjuku-ku, Tokyo 162-8655, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2004-0199DOI Listing
December 2004

An in vitro outgrowth culture system for normal human keratinocytes.

J Dermatol Sci 2004 Jun;35(1):19-28

Department of Tissue Regeneration, Research Institute, International Medical Center of Japan, 1-21-1 Toyama, Shinjuku-Ku, Tokyo 162-8655, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jdermsci.2004.03.005DOI Listing
June 2004

Characterization of multipotent adult stem cells from the skin: transforming growth factor-beta (TGF-beta) facilitates cell growth.

Exp Cell Res 2004 Apr;295(1):194-203

Department of Regenerative Medicine, Research Institute, International Medical Center of Japan, Tokyo 162-8655, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2003.12.027DOI Listing
April 2004

Mechanical stretching in vitro regulates signal transduction pathways and cellular proliferation in human epidermal keratinocytes.

J Invest Dermatol 2004 Mar;122(3):783-90

Department of Dermatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.0022-202X.2004.22328.xDOI Listing
March 2004

Interleukin 15 induces the signals of epidermal proliferation through ERK and PI 3-kinase in a human epidermal keratinocyte cell line, HaCaT.

Biochem Biophys Res Commun 2003 Feb;301(4):841-7

Department of Dermatology, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, 113-8655, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0006-291x(03)00060-3DOI Listing
February 2003