Hisham Abdel-Azim

Hisham Abdel-Azim

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Hisham Abdel-Azim

Hisham Abdel-Azim

Publications by authors named "Hisham Abdel-Azim"

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64Publications

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Pre-B acute lymphoblastic leukemia expresses cell surface nucleolin as a 9-O-acetylated sialoglycoprotein.

Sci Rep 2018 Nov 21;8(1):17174. Epub 2018 Nov 21.

Department of Systems Biology, Beckman Research Institute, City of Hope, Monrovia, CA, USA.

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http://dx.doi.org/10.1038/s41598-018-33873-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6249323PMC
November 2018

SCID genotype and 6-month posttransplant CD4 count predict survival and immune recovery.

Blood 2018 Oct 28;132(17):1737-1749. Epub 2018 Aug 28.

Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1182/blood-2018-03-840702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202916PMC
October 2018

Characterizing Deformability of Drug Resistant Patient-Derived Acute Lymphoblastic Leukemia (ALL) Cells Using Acoustic Tweezers.

Sci Rep 2018 Oct 24;8(1):15708. Epub 2018 Oct 24.

Department of Pediatrics, Division of Hematology, Oncology, Blood and Marrow Transplantation, Children's Hospital Los Angeles, University of Southern California, 4650 Sunset Blvd, Los Angeles, CA, 90027, USA.

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http://dx.doi.org/10.1038/s41598-018-34024-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6200731PMC
October 2018

Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008.

J Exp Clin Cancer Res 2018 Mar 27;37(1):67. Epub 2018 Mar 27.

Department of Systems Biology, Beckman Research Institute City of Hope, Monrovia, CA, USA.

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http://dx.doi.org/10.1186/s13046-018-0721-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870532PMC
March 2018

Humoral Immune Reconstitution Kinetics after Allogeneic Hematopoietic Stem Cell Transplantation in Children: A Maturation Block of IgM Memory B Cells May Lead to Impaired Antibody Immune Reconstitution.

Biol Blood Marrow Transplant 2017 Sep 8;23(9):1437-1446. Epub 2017 May 8.

Division of Hematology, Oncology, and Blood and Marrow Transplantation, Children's Hospital Los Angeles, Los Angeles, California; University of Southern California Keck School of Medicine, Los Angeles, California.

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http://dx.doi.org/10.1016/j.bbmt.2017.05.005DOI Listing
September 2017

The PI3Kδ Inhibitor Idelalisib Inhibits Homing in an in Vitro and in Vivo Model of B ALL.

Cancers (Basel) 2017 Sep 10;9(9). Epub 2017 Sep 10.

Department of Pediatrics, Division of Hematology, Oncology and Blood and Marrow Transplantation, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.3390/cancers9090121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615336PMC
September 2017

Role of αβ T Cell Depletion in Prevention of Graft versus Host Disease.

Biomedicines 2017 Jun 26;5(3). Epub 2017 Jun 26.

Section of Blood and Marrow Transplantation and Cellular Therapy, University of Alabama at Birmingham, Brimingham, AL 35294, USA.

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http://dx.doi.org/10.3390/biomedicines5030035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5618293PMC
June 2017

Phosphoflow-Based Evaluation of Mek Inhibitors as Small-Molecule Therapeutics for B-Cell Precursor Acute Lymphoblastic Leukemia.

PLoS One 2015 11;10(9):e0137917. Epub 2015 Sep 11.

Division of Hematology/Oncology and Bone Marrow Transplantation, The Saban Research Institute of Children's Hospital Los Angeles, Los Angeles, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137917PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567297PMC
May 2016

Reply: T-Cell Acute Lymphoblastic Leukemia, Minimal Residual Disease, and Lymphocyte Recovery.

Pediatr Blood Cancer 2016 May 14;63(5):945. Epub 2016 Jan 14.

Division of Hematology, Oncology, Blood and Marrow Transplantation, Children's Center for Cancer and Blood Disease, Children's Hospital Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1002/pbc.25899DOI Listing
May 2016

End of induction minimal residual disease alone is not a useful determinant for risk stratified therapy in pediatric T-cell acute lymphoblastic leukemia.

Pediatr Blood Cancer 2015 Nov 14;62(11):2040-3. Epub 2015 May 14.

Children's Center for Cancer and Blood Disease, Children's Hospital Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1002/pbc.25582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583337PMC
November 2015

Unrelated donor hematopoietic stem cell transplantation for the treatment of non-malignant genetic diseases: An alemtuzumab based regimen is associated with cure of clinical disease; earlier clearance of alemtuzumab may be associated with graft rejection.

Am J Hematol 2015 Nov 12;90(11):1021-6. Epub 2015 Oct 12.

Division of Hematology, Oncology and Blood and Marrow Transplantation, Children's Hospital Los Angeles, University of Southern California, Los Angeles, California.

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http://dx.doi.org/10.1002/ajh.24141DOI Listing
November 2015

Graft versus tumor effect in the brain of a child with recurrent metastatic medulloblastoma.

Pediatr Blood Cancer 2015 Sep 20;62(9):1667-9. Epub 2015 Apr 20.

Division of Hematology, Oncology and BMT, Nationwide Children's Hospital, Ohio State University, Columbus, Ohio.

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http://dx.doi.org/10.1002/pbc.25525DOI Listing
September 2015

Improved outcomes associated with hematopoietic stem cell transplantation for patients with juvenile myelomonocytic leukemia.

Blood 2015 Jul;126(4):561-2

Division of Hematology, Oncology and Blood & Marrow Transplantation, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1182/blood-2015-05-644161DOI Listing
July 2015

Low-dose total-body irradiation and alemtuzumab-based reduced-intensity conditioning regimen results in durable engraftment and correction of clinical disease among children with chronic granulomatous disease.

Pediatr Transplant 2015 Jun 2;19(4):408-12. Epub 2015 Apr 2.

Division of Hematology, Oncology, Blood and Marrow Transplantation, Children's Hospital Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1111/petr.12471DOI Listing
June 2015

Successful bone marrow transplantation of an adolescent young adult female with pregnancy-associated aplastic anemia.

J Pediatr Hematol Oncol 2015 May;37(4):319-21

*Blood and Marrow Transplantation, Children's Hospital Los Angeles †Pediatric Hematology Oncology, Department of Pediatrics, Mattel Children's Hospital, University of California Los Angeles, Los Angeles, CA ‡Pediatric Blood and Marrow Transplantation, Department of Pediatrics, The Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MPH.0000000000000314DOI Listing
May 2015

B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3.

Oncotarget 2015 May;6(13):11378-94

Section of Molecular Carcinogenesis, Division of Hematology/Oncology and Bone Marrow Transplant, The Saban Research Institute of Children's Hospital Los Angeles, Los Angeles, CA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484463PMC
http://dx.doi.org/10.18632/oncotarget.3409DOI Listing
May 2015

A survey of infectious disease clinical practices among pediatric blood and marrow transplant programs in the United States.

Pediatr Blood Cancer 2015 Apr 3;62(4):731-5. Epub 2015 Jan 3.

Blood and Marrow Transplantation, Children's Hospital Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1002/pbc.25355DOI Listing
April 2015

A reduced-toxicity regimen is associated with durable engraftment and clinical cure of nonmalignant genetic diseases among children undergoing blood and marrow transplantation with an HLA-matched related donor.

Biol Blood Marrow Transplant 2015 Mar 13;21(3):440-4. Epub 2014 Nov 13.

Division of Hematology, Oncology and Blood & Marrow Transplantation, Children's Hospital Los Angeles, University of Southern California, Los Angeles, California.

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https://linkinghub.elsevier.com/retrieve/pii/S10838791140067
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http://dx.doi.org/10.1016/j.bbmt.2014.11.005DOI Listing
March 2015

Potential of autologous NK cell therapy to eradicate leukemia: "Education is [not] the best provision for old age" -Aristotle.

Oncoimmunology 2015 Feb 6;4(2):e984549. Epub 2015 Mar 6.

Section of Molecular Carcinogenesis ; CA USA ; Division of Hematology/Oncology and Bone Marrow Transplantation; Department of Pediatrics; The Saban Research Institute of Children's Hospital Los Angeles ; CA USA ; Leukemia and Lymphoma Program; Norris Comprehensive Cancer Center; University of Southern California ; CA USA.

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http://dx.doi.org/10.4161/2162402X.2014.984549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4404799PMC
February 2015

Bortezomib for effective treatment of a child with refractory autoimmune hemolytic anemia post allogeneic hematopoietic stem cell transplant.

Pediatr Blood Cancer 2014 Dec 17;61(12):2324-5. Epub 2014 Aug 17.

Division of Hematology, Oncology, Blood and Marrow Transplantation, Children's Hospital Los Angeles, Los Angeles, California.

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http://dx.doi.org/10.1002/pbc.25172DOI Listing
December 2014

Obesity is associated with residual leukemia following induction therapy for childhood B-precursor acute lymphoblastic leukemia.

Blood 2014 Dec 27;124(26):3932-8. Epub 2014 Oct 27.

Children's Center for Cancer and Blood Disease, Children's Hospital Los Angeles, Los Angeles, CA; University of Southern California, Los Angeles, CA; Center for Endocrinology, Diabetes and Metabolism, Children's Hospital Los Angeles, Los Angeles, CA; and.

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http://dx.doi.org/10.1182/blood-2014-08-595389DOI Listing
December 2014

Overcoming psychosocial and developmental barriers to blood and marrow transplantation (BMT) in an adolescent/young adult (AYA) transgender patient with chronic myelogenous leukemia.

Pediatr Hematol Oncol 2014 Nov 22;31(8):765-7. Epub 2014 May 22.

Department of Pediatrics, Keck School of Medicine, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA.

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http://dx.doi.org/10.3109/08880018.2014.909914DOI Listing
November 2014

Immunologic resolution of human chronic graft-versus-host disease.

Biol Blood Marrow Transplant 2014 Oct 27;20(10):1508-15. Epub 2014 Jun 27.

Division of Blood and Marrow Transplantation, Children's Center for Cancer and Blood Diseases, Children's Hospital Los Angeles, and Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, California. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2014.06.030DOI Listing
October 2014

Human lymphoid development in the absence of common γ-chain receptor signaling.

J Immunol 2014 Jun 25;192(11):5050-8. Epub 2014 Apr 25.

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095; Department of Pediatrics, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles CA 90095;

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http://dx.doi.org/10.4049/jimmunol.1303496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4052377PMC
June 2014

Effector-mediated eradication of precursor B acute lymphoblastic leukemia with a novel Fc-engineered monoclonal antibody targeting the BAFF-R.

Mol Cancer Ther 2014 Jun 13;13(6):1567-77. Epub 2014 May 13.

Authors' Affiliations: Section of Molecular Carcinogenesis; Division of Hematology/Oncology and Bone Marrow Transplantation, The Saban Research Institute, Children's Hospital Los Angeles; Departments of Pediatrics and Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California; Oncology Translational Medicine and Oncology Research, Novartis Institutes for Biomedical Research, Novartis Pharmaceuticals, Cambridge, Massachusetts; and Autoimmunity, Transplantation and Inflammation, Novartis Institute for Biomedical Research, Basel, SwitzerlandAuthors' Affiliations: Section of Molecular Carcinogenesis; Division of Hematology/Oncology and Bone Marrow Transplantation, The Saban Research Institute, Children's Hospital Los Angeles; Departments of Pediatrics and Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California; Oncology Translational Medicine and Oncology Research, Novartis Institutes for Biomedical Research, Novartis Pharmaceuticals, Cambridge, Massachusetts; and Autoimmunity, Transplantation and Inflammation, Novartis Institute for Biomedical Research, Basel, SwitzerlandAuthors' Affiliations: Section of Molecular Carcinogenesis; Division of Hematology/Oncology and Bone Marrow Transplantation, The Saban Research Institute, Children's Hospital Los Angeles; Departments of Pediatrics and Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California; Oncology Translational Medicine and Oncology Research, Novartis Institutes for Biomedical Research, Novartis Pharmaceuticals, Cambridge, Massachusetts; and Autoimmunity, Transplantation and Inflammation, Novartis Institute for Biomedical Research, Basel, Switzerland

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http://dx.doi.org/10.1158/1535-7163.MCT-13-1023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067324PMC
June 2014

Circulating hematopoietic and endothelial progenitor cells in newborn infants: effects of gestational age, postnatal age and clinical stress in the first 3 weeks of life.

Early Hum Dev 2013 Jun 9;89(6):411-8. Epub 2013 Jan 9.

Division of Neonatal Medicine, Department of Pediatrics; Keck School of Medicine of the University of Southern California, LAC+USC Medical Center and Children's Hospital Los Angeles, Los Angeles, CA 90033, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S03783782120029
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http://dx.doi.org/10.1016/j.earlhumdev.2012.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633695PMC
June 2013

O-acetylated N-acetylneuraminic acid as a novel target for therapy in human pre-B acute lymphoblastic leukemia.

J Exp Med 2013 Apr 11;210(4):805-19. Epub 2013 Mar 11.

Section of Molecular Carcinogenesis, Division of Hematology/Oncology, The Saban Research Institute, Children's Hospital Los Angeles, CA 90089, USA.

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http://dx.doi.org/10.1084/jem.20121482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3620349PMC
April 2013

Clinical and genetic heterogeneity in Omenn syndrome and severe combined immune deficiency.

Pediatr Transplant 2009 Mar 5;13(2):244-50. Epub 2008 Sep 5.

Divisions of Hematology and Oncology, Children's Hospital Los Angeles, 4650 Sunset Blvd., Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.1111/j.1399-3046.2008.00970.xDOI Listing
March 2009

Pre- and post-natal treatment of hemophagocytic lymphohistiocytosis.

Pediatr Blood Cancer 2009 Jan;52(1):139-42

Division of Research Immunology, Childrens Hospital Los Angeles, California 90027, USA.

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http://dx.doi.org/10.1002/pbc.21778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2592085PMC
January 2009

Expansion of multipotent and lymphoid-committed human progenitors through intracellular dimerization of Mpl.

Blood 2008 Apr 3;111(8):4064-74. Epub 2008 Jan 3.

Division of Research Immunology/Bone Marrow Transplantation, Childrens Hospital Los Angeles, MS no. 62, 4650 Sunset Blvd, Los Angeles, CA 90027, USA.

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http://dx.doi.org/10.1182/blood-2007-08-107466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2288719PMC
April 2008

Congenital bilateral upper eyelid coloboma.

J Perinatol 2003 Mar;23(2):166-7

Metropolitan Hospital Center, New York Medical College, NY 10029, USA.

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http://dx.doi.org/10.1038/sj.jp.7210872DOI Listing
March 2003