Hiroyuki Watanabe

Hiroyuki Watanabe

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Hiroyuki Watanabe

Publications by authors named "Hiroyuki Watanabe"

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Manifestation of coronary subclavian steal phenomenon using reactive hyperemia in the ipsilateral forearm.

Echocardiography 2019 Oct 1. Epub 2019 Oct 1.

Department of Cardiovascular Medicine, Akita University Graduate School of Medicine, Akita, Japan.

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http://dx.doi.org/10.1111/echo.14485DOI Listing
October 2019

F-labeled benzimidazopyridine derivatives for PET imaging of tau pathology in Alzheimer's disease.

Bioorg Med Chem 2019 Aug 26;27(16):3587-3594. Epub 2019 Jun 26.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.06.039DOI Listing
August 2019

Cancer radiotheranostics targeting carbonic anhydrase-IX with In- and Y-labeled ureidosulfonamide scaffold for SPECT imaging and radionuclide-based therapy.

Theranostics 2018 30;8(11):2992-3006. Epub 2018 Apr 30.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.7150/thno.20982DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996370PMC
July 2019

Synthesis and biological evaluation of F-18 labeled tetrahydroisoquinoline derivatives targeting orexin 1 receptor.

Bioorg Med Chem Lett 2019 Jul 27;29(13):1620-1623. Epub 2019 Apr 27.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2019.04.044DOI Listing
July 2019

[Clinical Pharmacology Research for Promoting Individualized Cancer Chemotherapy].

Yakugaku Zasshi 2019 ;139(6):901-909

Department of Pharmacy, Kyushu University Hospital.

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http://dx.doi.org/10.1248/yakushi.18-00213-1DOI Listing
July 2019

Incorrect frozen elephant trunk deployment into the false lumen of a patient with complicated type B acute dissection.

Eur J Cardiothorac Surg 2019 Jun;55(6):1222-1224

Division of Cardiovascular Surgery, Narita Red Cross Hospital, Narita, Japan.

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http://dx.doi.org/10.1093/ejcts/ezy357DOI Listing
June 2019

Visualization of arterial wall vascularization using superb microvascular imaging in active-stage Takayasu arteritis.

Eur Heart J Cardiovasc Imaging 2019 Jun;20(6):719

Department of Cardiovascular Medicine, Akita University Graduate School of Medicine, 1-1-1, Hondoh, Akita, Japan.

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http://dx.doi.org/10.1093/ehjci/jey285DOI Listing
June 2019

Development of Technetium-99m-Labeled BODIPY-Based Probes Targeting Lipid Droplets Toward the Diagnosis of Hyperlipidemia-Related Diseases.

Molecules 2019 Jun 19;24(12). Epub 2019 Jun 19.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29, Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.3390/molecules24122283DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6631856PMC
June 2019

Safety and efficacy of PD-1 inhibitors in non-small cell lung cancer patients positive for antinuclear antibodies.

Lung Cancer 2019 04 29;130:5-9. Epub 2019 Jan 29.

Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2019.01.014DOI Listing
April 2019

Development of the Tc-Hydroxamamide Complex as a Probe Targeting Carbonic Anhydrase IX.

Mol Pharm 2019 04 20;16(4):1489-1497. Epub 2019 Mar 20.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences , Kyoto University , 46-29 Yoshida Shimoadachi-cho, Sakyo-ku , Kyoto 606-8501 , Japan.

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http://dx.doi.org/10.1021/acs.molpharmaceut.8b01120DOI Listing
April 2019

Is the new potent acid-inhibitory drug vonoprazan effective for healing idiopathic peptic ulcers? A multicenter observational study in Akita Prefecture, Japan.

J Gastroenterol 2019 Apr 29. Epub 2019 Apr 29.

Department of Gastroenterology, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita, Akita, 010-8543, Japan.

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http://dx.doi.org/10.1007/s00535-019-01587-5DOI Listing
April 2019

Investigation of Stress Levels before the Onset of Idiopathic Sudden Sensorineural Hearing Loss.

J Int Adv Otol 2019 Apr;15(1):51-55

Department of Otolaryngology, Head and Neck Surgery, Kitasato University, School of Medicine, Sagamihara, Japan.

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http://dx.doi.org/10.5152/iao.2019.6197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483419PMC
April 2019

Urinary D-serine level as a predictive biomarker for deterioration of renal function in patients with atherosclerotic risk factors.

Biomarkers 2019 Mar 23;24(2):159-165. Epub 2018 Oct 23.

a Department of Cardiovascular Medicine, Graduate School of Medicine , Akita University , Akita , Japan.

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http://dx.doi.org/10.1080/1354750X.2018.1528632DOI Listing
March 2019

Asymptomatic Coronary Artery Disease in Japanese Patients With the Acute Ischemic Stroke.

J Stroke Cerebrovasc Dis 2019 Mar 22;28(3):612-618. Epub 2018 Nov 22.

Department of Cardiology, Tachikawa Medical Center, Niigata, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.10.035DOI Listing
March 2019

Independently Tuned Frontier Orbital Energy Levels of 1,3,4,6,9b-Pentaazaphenalene Derivatives by the Conjugation Effect.

J Org Chem 2019 Mar 12;84(5):2768-2778. Epub 2019 Feb 12.

Department of Polymer Chemistry, Graduate School of Engineering , Kyoto University , Katsura, Nishikyo-ku, Kyoto 615-8510 , Japan.

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http://dx.doi.org/10.1021/acs.joc.8b03161DOI Listing
March 2019

Biomarkers for individualized dosage adjustments in immunosuppressive therapy using calcineurin inhibitors after organ transplantation.

Acta Pharmacol Sin 2019 Feb 27;40(2):151-159. Epub 2018 Jun 27.

Department of Clinical Pharmacology and Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kyushu University, Fukuoka, 812-8582, Japan.

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http://dx.doi.org/10.1038/s41401-018-0070-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329804PMC
February 2019

Loss of Apelin Augments Angiotensin II-Induced Cardiac Dysfunction and Pathological Remodeling.

Int J Mol Sci 2019 Jan 9;20(2). Epub 2019 Jan 9.

Department of Biochemistry and Metabolic Science, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.

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http://dx.doi.org/10.3390/ijms20020239DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358887PMC
January 2019

Negative mood invites psychotic false perception in dementia.

PLoS One 2018 1;13(6):e0197968. Epub 2018 Jun 1.

Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197968PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983458PMC
December 2018

Characterization of Novel F-Labeled Phenoxymethylpyridine Derivatives as Amylin Imaging Probes.

Mol Pharm 2018 12 8;15(12):5574-5584. Epub 2018 Nov 8.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences , Kyoto University , 46-29 Yoshida Shimoadachi-cho , Sakyo-ku, Kyoto 606-8501 , Japan.

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http://pubs.acs.org/doi/10.1021/acs.molpharmaceut.8b00756
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http://dx.doi.org/10.1021/acs.molpharmaceut.8b00756DOI Listing
December 2018

Successful treatment of disseminated intravascular coagulation associated with aortic dissection.

J Vasc Surg Cases Innov Tech 2018 Dec 4;4(4):268-271. Epub 2018 Dec 4.

Division of Cardiovascular Surgery, Narita Red Cross Hospital, Chiba, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S24684287183009
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http://dx.doi.org/10.1016/j.jvscit.2018.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282448PMC
December 2018

A successful salvage therapy with daptomycin and linezolid for right-sided infective endocarditis and septic pulmonary embolism caused by methicillin-resistant Staphylococcus aureus.

J Infect Chemother 2018 Oct 11;24(10):845-848. Epub 2018 Mar 11.

Department of Cardiovascular Surgery, Japanese Red Cross Narita Hospital, 90-1, Iida-chou, Narita City, Chiba, 286-8523, Japan.

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http://dx.doi.org/10.1016/j.jiac.2018.02.006DOI Listing
October 2018

Modifiable factors associated with prolonged door to balloon time in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.

Heart Vessels 2018 Oct 7;33(10):1139-1148. Epub 2018 May 7.

Department of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, 3-4-32 Todaijima, Urayasu, Chiba, 279-0001, Japan.

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http://dx.doi.org/10.1007/s00380-018-1164-yDOI Listing
October 2018

Risk of chromosomal aberration in spermatozoa during intracytoplasmic sperm injection.

J Reprod Dev 2018 Oct 7;64(5):371-376. Epub 2018 Jul 7.

Department of Biological Sciences, Asahikawa Medical University, Hokkaido 078-8510, Japan.

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http://dx.doi.org/10.1262/jrd.2018-040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6189574PMC
October 2018

Novel fluorescence probes based on the chalcone scaffold for in vitro staining of β-amyloid plaques.

Bioorg Med Chem Lett 2018 10 8;28(19):3242-3246. Epub 2018 Aug 8.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.08.009DOI Listing
October 2018

Elasticity of the pronator teres muscle in youth baseball players with elbow injuries: evaluation using ultrasound strain elastography.

J Shoulder Elbow Surg 2018 Sep 22;27(9):1642-1649. Epub 2018 Jun 22.

Department of Physical Therapy, Akita University Graduate School of Health Sciences, Akita, Japan.

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http://dx.doi.org/10.1016/j.jse.2018.05.021DOI Listing
September 2018

Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics.

Mol Neurobiol 2018 Aug 30;55(8):7049-7061. Epub 2018 Jan 30.

Division of Biological Research on Drug Dependence, Department of Pharmaceutical Biosciences, Uppsala University, Box 591, BMC Husargatan 3, SE-75124, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s12035-017-0844-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061161PMC
August 2018

Pathogenic Factors Associated With Osgood-Schlatter Disease in Adolescent Male Soccer Players: A Prospective Cohort Study.

Orthop J Sports Med 2018 Aug 28;6(8):2325967118792192. Epub 2018 Aug 28.

Department of Rehabilitation, School of Allied Health Sciences, Kitasato University, Sagamihara, Japan.

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http://journals.sagepub.com/doi/10.1177/2325967118792192
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http://dx.doi.org/10.1177/2325967118792192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113738PMC
August 2018

Conversion of iodine to fluorine-18 based on iodinated chalcone and evaluation for β-amyloid PET imaging.

Bioorg Med Chem 2018 07 3;26(12):3352-3358. Epub 2018 May 3.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S09680896183050
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http://dx.doi.org/10.1016/j.bmc.2018.05.001DOI Listing
July 2018

Validity of Ultrasound Lung Comets for Assessment of the Severity of Interstitial Pneumonia.

J Ultrasound Med 2018 Jun 30;37(6):1523-1531. Epub 2017 Nov 30.

Department of Internal Medicine, Division of Cardiovascular and Respiratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.

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http://dx.doi.org/10.1002/jum.14497DOI Listing
June 2018

Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics.

Transl Psychiatry 2018 06 20;8(1):122. Epub 2018 Jun 20.

Division of Biological Research on Drug Dependence, Department of Pharmaceutical Biosciences, Uppsala University, SE-751 24, Uppsala, Sweden.

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http://dx.doi.org/10.1038/s41398-017-0075-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010434PMC
June 2018

Constrictive Pericarditis as a Long-term Undetermined Etiology of Ascites and Edema.

Intern Med 2018 May 11;57(10):1487-1491. Epub 2018 Jan 11.

Heart Center, Tokyo Bay Urayasu-Ichikawa Medical Center, Japan.

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http://dx.doi.org/10.2169/internalmedicine.9455-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5995698PMC
May 2018

Sentence composition ability in two patients with non-fluent/agrammatic variant primary progressive aphasia.

Psychogeriatrics 2018 May 6;18(3):231-234. Epub 2018 Feb 6.

Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Sendai, Japan.

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http://doi.wiley.com/10.1111/psyg.12311
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http://dx.doi.org/10.1111/psyg.12311DOI Listing
May 2018

Structure-activity relationships of succinimidyl-Cys-C(O)-Glu derivatives with different near-infrared fluorophores as optical imaging probes for prostate-specific membrane antigen.

Bioorg Med Chem 2018 05 10;26(9):2291-2301. Epub 2018 Mar 10.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, 46-29, Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2018.03.015DOI Listing
May 2018

Structure-Activity Relationships of Radioiodinated Benzoimidazopyridine Derivatives for Detection of Tau Pathology.

ACS Med Chem Lett 2018 May 10;9(5):478-483. Epub 2018 Apr 10.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://pubs.acs.org/doi/10.1021/acsmedchemlett.8b00092
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http://dx.doi.org/10.1021/acsmedchemlett.8b00092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5949832PMC
May 2018

Significance of intravascular ultrasound and exercise stress echocardiography in diagnosis of exercise-induced vasospastic angina at the site of moderate stenosis.

J Med Ultrason (2001) 2018 Apr 17;45(2):315-317. Epub 2017 Aug 17.

Department of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, 3-4-32 Todaijima, Urayasu, Chiba, 279-0001, Japan.

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http://dx.doi.org/10.1007/s10396-017-0815-4DOI Listing
April 2018

Recurrent aortic root pseudoaneurysm after transcatheter occlusion-A word of caution.

J Card Surg 2018 Apr 13;33(4):190-193. Epub 2018 Apr 13.

Department of Cardiovascular Surgery, Tokyo Bay Urayasu Ichikawa Medical Center, Urayasu-shi, Chiba, Japan.

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http://dx.doi.org/10.1111/jocs.13568DOI Listing
April 2018

Morphological Determinants of Obstructive Hypertrophic Cardiomyopathy Obtained Using Echocardiography.

Int Heart J 2018 Mar 23;59(2):339-346. Epub 2018 Feb 23.

Department of Cardiovascular and Respiratory Medicine, Akita University Graduate School of Medicine.

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http://dx.doi.org/10.1536/ihj.17-072DOI Listing
March 2018

Simultaneous appearance of intracardiac masses following chemotherapy in a patient with lung cancer.

Eur Heart J Cardiovasc Imaging 2018 01;19(1):119

Department of Cardiovascular and Respiratory Medicine, Akita University Graduate School of Medicine, 1-1-1, Hondoh, Akita 010-8543, Japan.

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http://dx.doi.org/10.1093/ehjci/jex220DOI Listing
January 2018

[Development of SPECT Probes for In Vivo Imaging of β-Amyloid and Tau Aggregates in the Alzheimer's Disease Brain].

Yakugaku Zasshi 2017 ;137(11):1361-1365

Graduate School of Pharmaceutical Sciences, Kyoto University.

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http://dx.doi.org/10.1248/yakushi.17-00156DOI Listing
January 2018

Antiemetic efficacy and safety of granisetron or palonosetron alone and in combination with a corticosteroid for ABVD therapy-induced nausea and vomiting.

J Pharm Health Care Sci 2018 9;4. Epub 2018 Jan 9.

3Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, 3-1-1, Maidashi, Higashi-ku, Fukuoka City, 812-8582 Japan.

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http://dx.doi.org/10.1186/s40780-017-0097-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761115PMC
January 2018

The impacts of dopamine D2 receptor polymorphism and antipsychotic dosage on dopamine supersensitivity psychosis in schizophrenia.

Schizophr Res 2017 12 9;190:182-183. Epub 2017 Mar 9.

Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuou-ku, Chiba, Chiba 260-8670, Japan.

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http://dx.doi.org/10.1016/j.schres.2017.03.014DOI Listing
December 2017

Synthesis and biological evaluation of novel radioiodinated benzimidazole derivatives for imaging α-synuclein aggregates.

Bioorg Med Chem 2017 12 14;25(24):6398-6403. Epub 2017 Oct 14.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1016/j.bmc.2017.10.010DOI Listing
December 2017

Stromal interaction molecule 1 haploinsufficiency causes maladaptive response to pressure overload.

PLoS One 2017 16;12(11):e0187950. Epub 2017 Nov 16.

Department of Cardiovascular and Respiratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0187950PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5690472PMC
December 2017

Effect of educational intervention on attitudes toward the concept of criminal responsibility.

World J Psychiatry 2017 Dec 22;7(4):197-206. Epub 2017 Dec 22.

Department of Psychiatry, Graduate School of Medicine, Chiba University, Chiba 2608670, Japan.

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http://dx.doi.org/10.5498/wjp.v7.i4.197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746663PMC
December 2017

Synthesis and evaluation of a novel near-infrared fluorescent probe based on succinimidyl-Cys-C(O)-Glu that targets prostate-specific membrane antigen for optical imaging.

Bioorg Med Chem Lett 2017 11 18;27(21):4876-4880. Epub 2017 Sep 18.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, 46-29, Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.09.037DOI Listing
November 2017

A Cardiac Calcified Amorphous Tumor Associated with End-stage Renal Disease: An Emerging Disease Concept.

Intern Med 2017 11 16;56(22):2967-2968. Epub 2017 Oct 16.

Department of Cardiovascular and Respiratory Medicine, Akita University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.2169/internalmedicine.9348-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725847PMC
November 2017

Inflammatory aneurysm of ileocolic artery discovered on fluorine 18-fluorodeoxyglucose-positron emission tomography/computed tomography.

J Vasc Surg 2017 11;66(5):1574-1575

Department of Cardiovascular Medicine, Akita University Graduate School of Medicine, Akita, Japan.

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http://dx.doi.org/10.1016/j.jvs.2016.07.132DOI Listing
November 2017

Variant Angina Leading to Cardiac Arrest in a Patient With Moyamoya Disease.

JACC Cardiovasc Interv 2017 11 1;10(22):e207-e208. Epub 2017 Nov 1.

Department of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, Chiba, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S19368798173107
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http://dx.doi.org/10.1016/j.jcin.2017.05.038DOI Listing
November 2017

Synthesis and biological evaluation of an In-labeled exendin-4 derivative as a single-photon emission computed tomography probe for imaging pancreatic β-cells.

Bioorg Med Chem 2017 10 7;25(20):5772-5778. Epub 2017 Sep 7.

Department of Patho-Functional Bioanalysis, Kyoto University Graduate School of Pharmaceutical Sciences, 46-29, Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2017.09.005DOI Listing
October 2017

Association Between Endothelial Progenitor Cells and Treatment Response in Non-Squamous Non-small Cell Lung Cancer Treated with Bevacizumab.

Anticancer Res 2017 10;37(10):5565-5571

Department of Cardiovascular and Respiratory Medicine, Akita University Graduate School of Medicine, Akita, Japan.

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http://dx.doi.org/10.21873/anticanres.11989DOI Listing
October 2017

Deconstructing psychosis and misperception symptoms in Parkinson's disease.

J Neurol Neurosurg Psychiatry 2017 09 9;88(9):722-729. Epub 2017 Jun 9.

Department of Behavioral Neurology and Cognitive Neuroscience, Tohoku University School of Medicine, Sendai, Japan.

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http://dx.doi.org/10.1136/jnnp-2017-315741DOI Listing
September 2017

Discovery of novel pyrazolo[1,5-a]pyridine-based EP receptor antagonists by scaffold hopping: Design, synthesis, and structure-activity relationships.

Bioorg Med Chem Lett 2017 09 25;27(17):4044-4050. Epub 2017 Jul 25.

Watarase Research Center, Discovery Research Headquarters, Kyorin Pharmaceutical Co., Ltd., 1848, Nogi, Nogi-machi, Shimotsuga-gun, Tochigi 329-0114, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2017.07.055DOI Listing
September 2017

Cirsium maritimum Makino Inhibits the Antigen/Immunoglobulin-E-Mediated Allergic Response In Vitro and In Vivo.

J Agric Food Chem 2017 Sep 19;65(38):8386-8391. Epub 2017 Sep 19.

Department of Nutrition, University of Kochi , Kochi, Kochi 781-8515, Japan.

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http://dx.doi.org/10.1021/acs.jafc.7b03322DOI Listing
September 2017

Novel Benzothiazole Derivatives as Fluorescent Probes for Detection of β-Amyloid and α-Synuclein Aggregates.

ACS Chem Neurosci 2017 08 3;8(8):1656-1662. Epub 2017 May 3.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University , 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto 606-8501, Japan.

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http://dx.doi.org/10.1021/acschemneuro.6b00450DOI Listing
August 2017

Preservation of chromosomal integrity in murine spermatozoa derived from gonocytes and spermatogonial stem cells surviving prenatal and postnatal exposure to γ-rays in mice.

Mol Reprod Dev 2017 Jul 31;84(7):638-648. Epub 2017 May 31.

Department of Biological Sciences, Asahikawa Medical University, Asahikawa, Hokkaido, Japan.

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http://dx.doi.org/10.1002/mrd.22832DOI Listing
July 2017

ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage.

Cardiovasc Res 2017 Jun;113(7):760-769

Department of Biochemistry and Metabolic Science, Akita University Graduate School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.

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http://dx.doi.org/10.1093/cvr/cvx061DOI Listing
June 2017

Radioiodination of BODIPY and its application to a nuclear and optical dual functional labeling agent for proteins and peptides.

Sci Rep 2017 06 13;7(1):3337. Epub 2017 Jun 13.

Department of Patho-Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida Shimoadachi-cho, Sakyo-ku, Kyoto, 606-8501, Japan.

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http://dx.doi.org/10.1038/s41598-017-03419-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469783PMC
June 2017

Acute aortic regurgitation in a bicuspid aortic valve due to the rupture of an anomalous cord.

Anatol J Cardiol 2017 Jun;17(6):E5

Department of Cardiovascular Medicine, Akita University Graduate School of Medicine, Akita-Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477088PMC
http://dx.doi.org/10.14744/AnatolJCardiol.2017.7822DOI Listing
June 2017

Neuropeptide imaging in rat spinal cord with MALDI-TOF MS: Method development for the application in pain-related disease studies.

Eur J Mass Spectrom (Chichester) 2017 Jun 7;23(3):105-115. Epub 2017 May 7.

1 Analytical Chemistry, Department of Chemistry - BMC, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1177/1469066717703272DOI Listing
June 2017

Efficacy of clozapine on dopamine supersensitivity psychosis in schizophrenia.

Int Clin Psychopharmacol 2017 05;32(3):169-173

aDepartment of Psychiatry, Graduate School of Medicine bDivision of Medical Treatment and Rehabilitation, Center for Forensic Mental Health, Chiba University, Chiba, Japan cClinic for Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Munich, Germany.

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http://Insights.ovid.com/crossref?an=00004850-201705000-0000
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http://dx.doi.org/10.1097/YIC.0000000000000160DOI Listing
May 2017

Low plasma concentration of gefitinib in patients with EGFR exon 21 L858R point mutations shortens progression-free survival.

Cancer Chemother Pharmacol 2017 May 8;79(5):1013-1020. Epub 2017 Apr 8.

Department of Cardiovascular and Respiratory Medicine, Akita University Graduate School of Medicine, Hondo 1-1-1, Akita, 010-8543, Japan.

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http://dx.doi.org/10.1007/s00280-017-3285-xDOI Listing
May 2017

Development of emissive aminopentaazaphenalene derivatives employing a design strategy for obtaining luminescent conjugated molecules by modulating the symmetry of molecular orbitals with substituent effects.

Chem Commun (Camb) 2017 May;53(36):5036-5039

Department of Polymer Chemistry, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

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http://xlink.rsc.org/?DOI=C7CC01287J
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http://dx.doi.org/10.1039/c7cc01287jDOI Listing
May 2017

Rapidly growing intraventricular mass in a patient with hereditary haemorrhagic telangiectasia.

Eur Heart J Cardiovasc Imaging 2017 Apr;18(4):423

Department of Cardiovascular and Respiratory Medicine, Akita University Graduate School of Medicine, 1-1-1, Hondoh, Akita 010-8543, Japan.

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http://dx.doi.org/10.1093/ehjci/jew305DOI Listing
April 2017

The involvement of spinal release of histamine on nociceptive behaviors induced by intrathecally administered spermine.

Eur J Pharmacol 2017 Apr 26;800:9-15. Epub 2017 Jan 26.

Department of Physiology and Anatomy, Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-4-1 Komatsushima, Aoba-ku, Sendai 981-8558, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ejphar.2017.01.031DOI Listing
April 2017

Damaged reward areas in human alcoholics: neuronal proportion decline and astrocyte activation.

Acta Neuropathol 2017 03 17;133(3):485-487. Epub 2017 Jan 17.

Division of Biological Research on Drug Dependence, Department of Pharmaceutical Biosciences, Uppsala University, Box 591, BMC Husargatan 3, SE-75124, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s00401-017-1675-0DOI Listing
March 2017

Successfully Treated Nonocclusive Mesenteric Ischemia After Transcatheter Aortic Valve Replacement.

Ann Thorac Surg 2017 Feb;103(2):e171-e173

Department of Cardiology, Tokyo Bay Urayasu Ichikawa Medical Center, Chiba, Japan.

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http://dx.doi.org/10.1016/j.athoracsur.2016.07.064DOI Listing
February 2017

Uncovering Adiponectin Replenishing Property of Sujiaonori Algal Biomaterial in Humans.

Mar Drugs 2017 Feb 8;15(2). Epub 2017 Feb 8.

Graduate School of Health & Nursing Sciences, University of Kochi, Kochi 781-8515, Japan.

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http://dx.doi.org/10.3390/md15020032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5334612PMC
February 2017

[An example of the socio-economic rehabilitation program for ex-leprosy patients in Vietnam and its evaluation by the patients].

Nihon Hansenbyo Gakkai Zasshi 2016 Dec;85(3):133-52

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December 2016