Hiroyuki Nakamura

Hiroyuki Nakamura

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Hiroyuki Nakamura

Publications by authors named "Hiroyuki Nakamura"

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Accumulation of sphingomyelin in Niemann-Pick disease type C cells disrupts Rab9-dependent vesicular trafficking of cholesterol.

J Cell Physiol 2020 Mar 6;235(3):2300-2309. Epub 2019 Sep 6.

Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chuo-ku, Chiba, Japan.

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http://dx.doi.org/10.1002/jcp.29137DOI Listing
March 2020

Carrier proteins-based boron delivery to tumor.

Appl Radiat Isot 2020 Mar 30;157:109011. Epub 2019 Nov 30.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.apradiso.2019.109011DOI Listing
March 2020

Suppression of HIF-1α accumulation by betulinic acid through proteasome activation in hypoxic cervical cancer.

Biochem Biophys Res Commun 2020 Mar 14;523(3):726-732. Epub 2020 Jan 14.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, 226-8503, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.01.031DOI Listing
March 2020

Thiamine Deficiency in a Nondrinker and Secondary Pulmonary Edema after Thiamine Replenishment.

Intern Med 2020 Feb 18;59(3):373-376. Epub 2019 Sep 18.

Department of Internal Medicine, Tomakomai City Hospital, Japan.

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http://dx.doi.org/10.2169/internalmedicine.3585-19DOI Listing
February 2020

Serum C-Reactive Protein Level Predicts Clinical Outcomes in Patients With Non-Small Cell Lung Cancer Harboring EGFR Mutations.

Cancer Invest 2020 Feb 5;38(2):122-129. Epub 2020 Feb 5.

Department of Respiratory Medicine, Tokyo Medical University Ibaraki Medical Center, Ibaraki, Japan.

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http://dx.doi.org/10.1080/07357907.2020.1721522DOI Listing
February 2020

Animal Models for Gammaherpesvirus Infections: Recent Development in the Analysis of Virus-Induced Pathogenesis.

Pathogens 2020 Feb 12;9(2). Epub 2020 Feb 12.

Department of Allergy and Clinical Immunology, National Research Institute for Child Health and Development, Tokyo 157-8535, Japan.

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http://dx.doi.org/10.3390/pathogens9020116DOI Listing
February 2020

Review Article (RESPNB_2019_334-R3) What Are Appropriate Values of Relative Krogh Diffusion Constant of NO against CO and of Theta-NO in Alveolar Septa?

Respir Physiol Neurobiol 2020 Feb 14:103415. Epub 2020 Feb 14.

Department of Respiratory Medicine, Tokyo Medical University, Tokyo 160-0023, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.resp.2020.103415DOI Listing
February 2020

Design, synthesis, and evaluation of indeno[2,1-c]pyrazolones for use as inhibitors against hypoxia-inducible factor (HIF)-1 transcriptional activity.

Bioorg Med Chem 2020 Jan 9;28(1):115207. Epub 2019 Nov 9.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.115207DOI Listing
January 2020

Single-Step, Rapid, and Mild Synthesis of β-Amino Acid N-Carboxy Anhydrides Using Micro-Flow Technology.

Chem Asian J 2020 Jan 28;15(1):79-84. Epub 2019 Nov 28.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.

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http://dx.doi.org/10.1002/asia.201901429DOI Listing
January 2020

A case of miliary tuberculosis presenting as massive hepatosplenomegaly and fatal hepatic failure.

IDCases 2020 29;19:e00707. Epub 2020 Jan 29.

Department of Respiratory Medicine, Tokyo Medical University Ibaraki Medical Center, 3-20-1 Chuou, Ami, Inashiki, Ibaraki, 300-0395, Japan.

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http://dx.doi.org/10.1016/j.idcr.2020.e00707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011022PMC
January 2020

Organizing Pneumonia Complicated with Erythrodermic Psoriasis.

Intern Med 2019 12 21;58(24):3597-3598. Epub 2019 Aug 21.

Department of Internal Medicine, Tomakomai City Hospital, Japan.

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https://www.jstage.jst.go.jp/article/internalmedicine/advpub
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http://dx.doi.org/10.2169/internalmedicine.3299-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6949458PMC
December 2019

Design, synthesis, and evaluation of azo D-π-A dyes as photothermal agents.

Org Biomol Chem 2019 12;18(1):93-101

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, 226-8503, Japan.

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http://dx.doi.org/10.1039/c9ob02066gDOI Listing
December 2019

Reduced diffusing capacity for carbon monoxide predicts borderline pulmonary arterial pressure in patients with systemic sclerosis.

Rheumatol Int 2019 Nov 6;39(11):1883-1887. Epub 2019 Jul 6.

Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N15W7, Kita-ku, Sapporo, Japan.

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http://dx.doi.org/10.1007/s00296-019-04370-0DOI Listing
November 2019

Peptide-Chain Elongation Using Unprotected Amino Acids in a Micro-Flow Reactor.

Chemistry 2019 Nov 24;25(66):15091-15097. Epub 2019 Oct 24.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.

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http://dx.doi.org/10.1002/chem.201903531DOI Listing
November 2019

Protein Chemical Labeling Using Biomimetic Radical Chemistry.

Molecules 2019 Nov 3;24(21). Epub 2019 Nov 3.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama 226-8503, Japan.

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http://dx.doi.org/10.3390/molecules24213980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864698PMC
November 2019

Antimitochondrial antibody-associated myopathy with pulmonary hypertension due to left heart disease.

Rheumatology (Oxford) 2019 Nov 27. Epub 2019 Nov 27.

Department of Internal Medicine, Tomakomai City Hospital, Tomakomai.

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http://dx.doi.org/10.1093/rheumatology/kez585DOI Listing
November 2019

Catalyst-proximity protein chemical labelling on affinity beads targeting endogenous lectins.

Chem Commun (Camb) 2019 Oct;55(88):13275-13278

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259-R1-13, Nagatsuta-cho, Midori-ku, Yokohama, Kanagawa 226-8503, Japan.

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http://dx.doi.org/10.1039/c9cc05231cDOI Listing
October 2019

Varicella Zoster Virus Encephalitis Mimicking Nivolumab-Induced Autoimmune Neuropathy in a Patient with Lung Cancer.

J Thorac Oncol 2019 08;14(8):e163-e165

Department of Respiratory Medicine, Tokyo Medical University Ibaraki Medical Center, Ibaraki, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2019.02.033DOI Listing
August 2019

Corticosterone inhibits the expression of cannabinoid receptor-1 and cannabinoid receptor agonist-induced decrease in cell viability in glioblastoma cells.

Oncol Lett 2019 Aug 7;18(2):1557-1563. Epub 2019 Jun 7.

Faculty of Health Sciences, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Ishikawa 920-0942, Japan.

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http://dx.doi.org/10.3892/ol.2019.10456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6607110PMC
August 2019

Clinicopathological Significance of the ET Axis in Human Oral Squamous Cell Carcinoma.

Pathol Oncol Res 2019 Jul 31;25(3):1083-1089. Epub 2018 Oct 31.

Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, 13-1 Takara-machi, Kanazawa, 920-8641, Japan.

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http://dx.doi.org/10.1007/s12253-018-0514-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614151PMC
July 2019

Structure-based drug design of novel carborane-containing nicotinamide phosphoribosyltransferase inhibitors.

Bioorg Med Chem 2019 Jul 10;27(13):2832-2844. Epub 2019 May 10.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.05.013DOI Listing
July 2019

Rhodium(iii)-catalysed carboxylate-directed C-H functionalizations of isoxazoles with alkynes.

Chem Commun (Camb) 2019 Jul 20;55(58):8382-8385. Epub 2019 Jun 20.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, 226-8503, Japan.

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http://dx.doi.org/10.1039/c9cc03283eDOI Listing
July 2019

Efficacy of dual antiplatelet therapy for preventing recurrence of arterial thrombosis in patients with antiphospholipid syndrome.

Rheumatology (Oxford) 2019 06;58(6):969-974

Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

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http://dx.doi.org/10.1093/rheumatology/key340DOI Listing
June 2019

Case of autoimmune intraepidermal and subepidermal blistering disease in which autoantibodies to desmoglein 1 and BP230 coexist.

J Dermatol 2019 Jun 14;46(6):e215-e216. Epub 2018 Dec 14.

Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

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http://dx.doi.org/10.1111/1346-8138.14734DOI Listing
June 2019

Design of S-S bond containing maleimide-conjugated closo-dodecaborate (SSMID): identification of unique modification sites on albumin and investigation of intracellular uptake.

Org Biomol Chem 2019 06;17(22):5496-5499

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, R1-13, 4259, Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.

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http://dx.doi.org/10.1039/c9ob00584fDOI Listing
June 2019

Orb-weaving spider Araneus ventricosus genome elucidates the spidroin gene catalogue.

Sci Rep 2019 Jun 10;9(1):8380. Epub 2019 Jun 10.

Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Kakuganji, Tsuruoka, Yamagata, 997-0052, Japan.

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http://dx.doi.org/10.1038/s41598-019-44775-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557832PMC
June 2019

Acute respiratory failure due to eosinophilic pneumonia following pneumococcal vaccination.

Hum Vaccin Immunother 2019 26;15(12):2914-2916. Epub 2019 Jun 26.

Department of Respiratory Medicine, Tokyo Medical University Ibaraki Medical Center, Ibaraki, Japan.

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http://dx.doi.org/10.1080/21645515.2019.1631134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6930081PMC
June 2019

Selectively high efficacy of eribulin against high-grade invasive recurrent and/or metastatic squamous cell carcinoma of the head and neck.

Oncol Lett 2019 Jun 19;17(6):5064-5072. Epub 2019 Mar 19.

Department of Oral and Maxillofacial Surgery, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa 920-8640, Japan.

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http://dx.doi.org/10.3892/ol.2019.10165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507455PMC
June 2019

Triclosan-induced alteration of gut microbiome and aggravation of asthmatic airway response in aeroallergen-sensitized mice.

Allergy 2019 05 1;74(5):996-999. Epub 2019 Feb 1.

Department of Environmental and Preventive Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Japan.

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http://dx.doi.org/10.1111/all.13639DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6590208PMC
May 2019

Heat attenuates sensitivity of mammalian cells to capsaicin.

J Biochem Mol Toxicol 2019 May 23;33(5):e22288. Epub 2019 Jan 23.

Department of Environmental Physiology, School of Medicine, Shimane University, Izumo, Japan.

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http://dx.doi.org/10.1002/jbt.22288DOI Listing
May 2019

Relationship between saturated fatty acid intake and hypertension and oxidative stress.

Nutrition 2019 05 26;61:8-15. Epub 2018 Oct 26.

Department of Environmental and Preventive Medicine, Graduate School of Medical Science, Kanazawa University, Japan.

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http://dx.doi.org/10.1016/j.nut.2018.10.020DOI Listing
May 2019

Translocation and activation of sphingosine kinase 1 by ceramide-1-phosphate.

J Cell Biochem 2019 Apr 15;120(4):5396-5408. Epub 2018 Nov 15.

Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.

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http://doi.wiley.com/10.1002/jcb.27818
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http://dx.doi.org/10.1002/jcb.27818DOI Listing
April 2019

Hypercapnic tumor microenvironment confers chemoresistance to lung cancer cells by reprogramming mitochondrial metabolism in vitro.

Free Radic Biol Med 2019 04 10;134:200-214. Epub 2019 Jan 10.

Department of Respiratory Medicine, Tokyo Medical University Ibaraki Medical Center, 3-20-1 Chuou, Ami-machi, Ibaraki 300-0395, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2019.01.014DOI Listing
April 2019

Dietary Calcium Intake and Hypertension: Importance of Serum Concentrations of 25-Hydroxyvitamin D.

Nutrients 2019 Apr 23;11(4). Epub 2019 Apr 23.

Department of Environmental and Preventive Medicine, Graduate School of Medical Science, Kanazawa University, Ishikawa 920-8640, Japan.

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http://dx.doi.org/10.3390/nu11040911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6521038PMC
April 2019

The bagworm genome reveals a unique fibroin gene that provides high tensile strength.

Commun Biol 2019 29;2:148. Epub 2019 Apr 29.

1Institute for Advanced Biosciences, Keio University, Yamagata, Japan.

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http://dx.doi.org/10.1038/s42003-019-0412-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6488591PMC
April 2019

N'-acyl-N-methylphenylenediamine as a novel proximity labeling agent for signal amplification in immunohistochemistry.

Bioorg Med Chem 2019 03 31;27(6):1110-1118. Epub 2019 Jan 31.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2019.01.036DOI Listing
March 2019

Phosphorylation and inhibition of ceramide kinase by protein kinase C-β: Their changes by serine residue mutations.

Cell Signal 2019 02 15;54:59-68. Epub 2018 Nov 15.

Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8675, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S08986568183027
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http://dx.doi.org/10.1016/j.cellsig.2018.11.008DOI Listing
February 2019

Association between Lower Intake of Minerals and Depressive Symptoms among Elderly Japanese Women but Not Men: Findings from Shika Study.

Nutrients 2019 Feb 13;11(2). Epub 2019 Feb 13.

Department of Environmental and Preventive Medicine, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa 920-8640, Japan.

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http://dx.doi.org/10.3390/nu11020389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412241PMC
February 2019

Estimated glomerular filtration rate decline and risk of end-stage renal disease in type 2 diabetes.

PLoS One 2018 2;13(8):e0201535. Epub 2018 Aug 2.

Department of Nephrology, Kanazawa University Hospital, Kanazawa, Japan / Department of Disease Control and Homeostasis, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201535PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072050PMC
January 2019

Elucidating the mode of action for thiophene-based organic D-π-A sensitizers for use in photodynamic therapy.

Bioorg Med Chem 2019 01 6;27(2):315-321. Epub 2018 Dec 6.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2018.12.006DOI Listing
January 2019

Glossopharyngeal/vagus nerve disorder due to IgG4-related hypertrophic pachymeningitis.

Rheumatology (Oxford) 2019 Jan 30. Epub 2019 Jan 30.

Department of Internal Medicine, Tomakomai City Hospital, Tomakomai, Japan.

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http://dx.doi.org/10.1093/rheumatology/kez009DOI Listing
January 2019

Presence of a Synergistic Interaction Between Current Cigarette Smoking and Diabetes Mellitus on Development of Dementia in Older Adults.

J Alzheimers Dis 2019 ;71(3):833-840

Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan.

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http://dx.doi.org/10.3233/JAD-190340DOI Listing
January 2019

Ectopic RASGRP2 (CalDAG-GEFI) expression in rheumatoid synovium contributes to the development of destructive arthritis.

Ann Rheum Dis 2018 12 3;77(12):1765-1772. Epub 2018 Aug 3.

Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan.

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http://dx.doi.org/10.1136/annrheumdis-2018-213588DOI Listing
December 2018

Peptide Synthesis Utilizing Micro-flow Technology.

Chem Asian J 2018 Dec 5;13(24):3818-3832. Epub 2018 Nov 5.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.

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http://dx.doi.org/10.1002/asia.201801488DOI Listing
December 2018

Cellular density-dependent increases in HIF-1α compete with c-Myc to down-regulate human EP4 receptor promoter activity through Sp-1-binding region.

Pharmacol Res Perspect 2018 12 11;6(6):e00441. Epub 2018 Nov 11.

Department of Pharmacology for Life Sciences Graduate School of Pharmaceutical Sciences & Graduate School of Biomedical Sciences Tokushima University Tokushima Japan.

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http://doi.wiley.com/10.1002/prp2.441
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http://dx.doi.org/10.1002/prp2.441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6230926PMC
December 2018

Synthesis of 3-Hydroxy-4-Substituted Picolinonitriles from 4-Propargylaminoisoxazoles via Stepwise and One-Pot Isoxazolopyridine Formation/N-O Bond Cleavage Sequence.

ACS Omega 2018 Dec 3;3(12):16472-16476. Epub 2018 Dec 3.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, School of Life Science and Technology, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan.

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http://dx.doi.org/10.1021/acsomega.8b03114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6644211PMC
December 2018

Metallacarboranes on the Road to Anticancer Therapies: Cellular Uptake, DNA Interaction, and Biological Evaluation of Cobaltabisdicarbollide [COSAN].

Chemistry 2018 Nov 9;24(65):17239-17254. Epub 2018 Nov 9.

Institut de Ciència de Materials de Barcelona (ICMAB-CSIC), Campus UAB, 08193 Bellaterra, Barcelona, Spain.

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http://dx.doi.org/10.1002/chem.201803178DOI Listing
November 2018

Ointment vehicles regulate the wound-healing process by modifying the hyaluronan-rich matrix.

Wound Repair Regen 2018 11 18;26(6):437-445. Epub 2018 Oct 18.

Department of Advanced Medicine, Obu, Aichi, Japan.

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http://dx.doi.org/10.1111/wrr.12673DOI Listing
November 2018

Architecture of nanoscale ferroelectric domains in GaMoS.

J Phys Condens Matter 2018 Nov 26;30(44):445402. Epub 2018 Sep 26.

Institute of Applied Physics, Technische Universität Dresden, D-01062 Dresden, Germany.

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http://dx.doi.org/10.1088/1361-648X/aae448DOI Listing
November 2018

Elevated Levels of Serum IL-17A in Community-Dwelling Women with Higher Depressive Symptoms.

Behav Sci (Basel) 2018 Nov 4;8(11). Epub 2018 Nov 4.

Department of Public Health, Graduate School of Medicine, Kanazawa University, Kanazawa 920-8640, Japan.

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http://www.mdpi.com/2076-328X/8/11/102
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http://dx.doi.org/10.3390/bs8110102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262626PMC
November 2018

The usefulness of pleural fluid presepsin, C-reactive protein, and procalcitonin in distinguishing different causes of pleural effusions.

BMC Pulm Med 2018 Nov 23;18(1):176. Epub 2018 Nov 23.

Department of Internal Medicine, Hematology, Rheumatology and Respiratory Medicine, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.

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http://dx.doi.org/10.1186/s12890-018-0740-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251181PMC
November 2018

Relationship between Dietary -6 Fatty Acid Intake and Hypertension: Effect of Glycated Hemoglobin Levels.

Nutrients 2018 Nov 24;10(12). Epub 2018 Nov 24.

Department of Environmental and Preventive Medicine, Graduate School of Medical Science, Kanazawa University, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, Japan.

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http://www.mdpi.com/2072-6643/10/12/1825
Publisher Site
http://dx.doi.org/10.3390/nu10121825DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316654PMC
November 2018

The design, synthesis, and evaluation of organic dithienopyrrole-based D-π-A dyes for use as sensitizers in photodynamic therapy.

Bioorg Med Chem Lett 2018 10 17;28(18):3099-3104. Epub 2018 Jul 17.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.07.025DOI Listing
October 2018

Development of a new doubly-labeled fluorescent ceramide probe for monitoring the metabolism of sphingolipids in living cells.

Bioorg Med Chem Lett 2018 10 15;28(19):3222-3226. Epub 2018 Aug 15.

Laboratory of Synthetic Organic Chemistry, Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba, Japan; Molecular Chirality Research Center, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmcl.2018.08.013DOI Listing
October 2018

Kasabach-Merritt phenomenon with concurrent appearance of antiphospholipid antibodies in a patient with giant liver haemangioma.

Rheumatol Adv Pract 2018 24;2(2):rky047. Epub 2018 Oct 24.

Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

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http://dx.doi.org/10.1093/rap/rky047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649899PMC
October 2018

Autologous haematopoietic stem cell transplantation for Japanese patients with systemic sclerosis: Long-term follow-up on a phase II trial and treatment-related fatal cardiomyopathy.

Mod Rheumatol 2018 Sep 8;28(5):879-884. Epub 2018 Jan 8.

a Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine , Hokkaido University , Sapporo , Japan.

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http://dx.doi.org/10.1080/14397595.2017.1416920DOI Listing
September 2018

Knockout of Ceramide Kinase Aggravates Pathological and Lethal Responses in Mice with Experimental Colitis.

Biol Pharm Bull 2018 ;41(5):797-805

Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, Chiba University.

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http://dx.doi.org/10.1248/bpb.b18-00051DOI Listing
September 2018

Remission of Nephrotic Syndrome After Therapy for Chronic Hepatitis C Virus Infection in a Patient With Systemic Lupus Erythematosus.

Ann Intern Med 2018 09 1;169(5):352-353. Epub 2018 May 1.

Hokkaido University, Sapporo, Japan (H.N., Y.F., S.Y., M.N., T.A.).

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http://dx.doi.org/10.7326/L17-0759DOI Listing
September 2018

Rapid and Mild Synthesis of Amino Acid N-Carboxy Anhydrides: Basic-to-Acidic Flash Switching in a Microflow Reactor.

Angew Chem Int Ed Engl 2018 08 24;57(35):11389-11393. Epub 2018 Jul 24.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503, Japan.

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http://dx.doi.org/10.1002/anie.201803549DOI Listing
August 2018

Sitagliptin-induced diffuse alveolar hemorrhage mimicking pulmonary edema.

J Family Med Prim Care 2018 Mar-Apr;7(2):480-481

Department of Respiratory Medicine, Tokyo Medical University Ibaraki Medical Center, Ibaraki 300-0395, Japan.

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http://dx.doi.org/10.4103/jfmpc.jfmpc_160_17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060939PMC
August 2018

Target-protein-selective inactivation and labelling using an oxidative catalyst.

Org Biomol Chem 2018 08;16(34):6168-6179

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, 226-8503, Japan.

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http://dx.doi.org/10.1039/c8ob01484aDOI Listing
August 2018

o-Carboranylalkoxy-1,3,5-Triazine Derivatives: Synthesis, Characterization, X-ray Structural Studies, and Biological Activity.

Molecules 2018 Aug 30;23(9). Epub 2018 Aug 30.

Department of Chemistry, College of Natural Sciences, Chosun University, 309 Pilmundaero, Dong-gu, Gwangju 61452, Korea.

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http://dx.doi.org/10.3390/molecules23092194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225125PMC
August 2018

The four-domain structure model of a depression scale for medical students: A cross-sectional study in Haiphong, Vietnam.

PLoS One 2018 22;13(3):e0194550. Epub 2018 Mar 22.

Department of Environmental and Preventive Medicine, Graduate School of Medical Sciences, Kanazawa University, Kanazawa City, Ishikawa Prefecture, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0194550PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864022PMC
July 2018

Discovery of bicyclo[3,3,1]non-2-ene as a novel skeleton for HIF-1 inhibitors.

Bioorg Med Chem 2018 07 3;26(12):3345-3351. Epub 2018 May 3.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2018.05.002DOI Listing
July 2018

Low Back Pain With Radiographic Change in Sacroiliac Joints Mimicking Spondyloarthritis.

J Clin Rheumatol 2018 Jul 20. Epub 2018 Jul 20.

From the Department of Internal Medicine, Hokkaido Spinal Cord Injury Center, Bibai, Japan.

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http://dx.doi.org/10.1097/RHU.0000000000000863DOI Listing
July 2018

Efficient detection of pulmonary arterial hypertension using serum haptoglobin level and cardiac MRI in patients with connective tissue diseases: a pilot study.

Clin Exp Rheumatol 2018 Mar-Apr;36(2):345-346. Epub 2018 Feb 15.

Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

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June 2018

1-Methyl-4-aryl-urazole (MAUra) labels tyrosine in proximity to ruthenium photocatalysts.

Chem Commun (Camb) 2018 Jun;54(46):5871-5874

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, 226-8503, Japan.

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http://dx.doi.org/10.1039/c8cc02891eDOI Listing
June 2018

Ramucirumab-induced Multiple Haemangiomas of the Skin: Two Case Reports.

Acta Derm Venereol 2018 Apr;98(4):454-455

Department of Dermatology, Hokkaido University Graduate School of Medicine, North 15 West 7, Kita-ku, Sapporo 060-8638, Japan.

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http://dx.doi.org/10.2340/00015555-2869DOI Listing
April 2018

Alternative pathway activation due to low level of complement factor H in primary antiphospholipid syndrome.

Thromb Res 2018 04 21;164:63-68. Epub 2018 Feb 21.

Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, North-15 West-7, Kita-ku, Sapporo 060-8638, Japan.

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http://dx.doi.org/10.1016/j.thromres.2018.02.142DOI Listing
April 2018

Simultaneous measurement of pulmonary diffusing capacity for carbon monoxide and nitric oxide.

Respir Investig 2018 Mar 2;56(2):100-110. Epub 2018 Feb 2.

Department of Respiratory Medicine, Tokyo Medical University Ibaraki Medical Center, 3-20-1 Chuou, Ami-machi, Inashiki-gun, 300-0395 Ibaraki, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.resinv.2017.12.006DOI Listing
March 2018

[Development and Application of Catalytic Tyrosine Modification].

Yakugaku Zasshi 2018 ;138(1):39-46

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology.

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https://www.jstage.jst.go.jp/article/yakushi/138/1/138_17-00
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http://dx.doi.org/10.1248/yakushi.17-00186-1DOI Listing
February 2018

Regulation of programmed-death ligand in the human head and neck squamous cell carcinoma microenvironment is mediated through matrix metalloproteinase-mediated proteolytic cleavage.

Int J Oncol 2018 Feb 11;52(2):379-388. Epub 2017 Dec 11.

Department of Oral and Maxillofacial Surgery, Division of Cancer Medicine, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa 920-8640, Japan.

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http://dx.doi.org/10.3892/ijo.2017.4221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5741372PMC
February 2018

Gold(I)-Catalyzed Intramolecular SAr Reaction: Efficient Synthesis of Isoxazole-Containing Fused Heterocycles.

Org Lett 2018 01 5;20(2):433-436. Epub 2018 Jan 5.

Laboratory for Chemistry and Life Science, Institute of Innovative Research, Tokyo Institute of Technology , 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8503, Japan.

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http://dx.doi.org/10.1021/acs.orglett.7b03760DOI Listing
January 2018

Lung injury associated with electronic cigarettes inhalation diagnosed by transbronchial lung biopsy.

Respirol Case Rep 2018 01 17;6(1):e00282. Epub 2017 Nov 17.

Department of Pathology Japanese Red Cross Medical Center Tokyo Japan.

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http://dx.doi.org/10.1002/rcr2.282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757588PMC
January 2018