Publications by authors named "Hiroshi Takeshima"

148 Publications

Decreased cardiac pacemaking and attenuated β-adrenergic response in TRIC-A knockout mice.

PLoS One 2020 21;15(12):e0244254. Epub 2020 Dec 21.

Department of Biological Chemistry, Kyoto University Graduate School and Faculty of Pharmaceutical Sciences, Kyoto, Japan.

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December 2020

Calcium-induced calcium release and type 3 ryanodine receptors modulate the slow afterhyperpolarising current, sIAHP, and its potentiation in hippocampal pyramidal neurons.

PLoS One 2020 19;15(6):e0230465. Epub 2020 Jun 19.

Research Department of Neuroscience, Physiology and Pharmacology, University College London, London, England, United Kingdom.

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August 2020

TRIC-A Channel Maintains Store Calcium Handling by Interacting With Type 2 Ryanodine Receptor in Cardiac Muscle.

Circ Res 2020 02 6;126(4):417-435. Epub 2019 Dec 6.

From the Department of Surgery, Davis Heart and Lung Research Institute, The Ohio State University, Columbus (X. Zhou, K.H.P., P.-h.L., J.M.).

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February 2020

[Cancer cell-specific functional relation between Na,K-ATPase and volume-regulated anion channel].

Nihon Yakurigaku Zasshi 2019 ;154(3):103-107

Department of Pharmaceutical Physiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama.

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September 2019

Non-morphogenic effect of Sonic Hedgehog on gastric H,K-ATPase activity.

Biochem Biophys Res Commun 2019 10 21;518(3):605-609. Epub 2019 Aug 21.

Department of Pharmaceutical Physiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, 930-0194, Japan.

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October 2019

A junctophilin-caveolin interaction enables efficient coupling between ryanodine receptors and BK channels in the Ca microdomain of vascular smooth muscle.

J Biol Chem 2019 08 15;294(35):13093-13105. Epub 2019 Jul 15.

Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya 467-8603, Japan

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August 2019

[Negative regulation of gastric proton pump by desialylation suggested by fluorescent imaging with the sialic acid-specific nanoprobe].

Nihon Yakurigaku Zasshi 2019 ;153(6):261-266

Department of Pharmaceutical Physiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama.

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August 2019

Calcium phosphate mineralization in bone tissues directly observed in aqueous liquid by atmospheric SEM (ASEM) without staining: microfluidics crystallization chamber and immuno-EM.

Sci Rep 2019 05 14;9(1):7352. Epub 2019 May 14.

Division of Dental Pharmacology, Department of Developmental and Reconstructive Medicine, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8588, Japan.

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May 2019

Extraocular muscle function is impaired in mice.

J Gen Physiol 2019 07 13;151(7):929-943. Epub 2019 May 13.

Department of Anesthesia, Basel University Hospital, Basel, Switzerland

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July 2019

Nano-structural analysis of engrafted human induced pluripotent stem cell-derived cardiomyocytes in mouse hearts using a genetic-probe APEX2.

Biochem Biophys Res Commun 2018 11 15;505(4):1251-1256. Epub 2018 Oct 15.

Center for iPS Cell Research and Application, Kyoto University, Kyoto, 606-8507, Japan. Electronic address:

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November 2018

Crosstalk between Na,K-ATPase and a volume-regulated anion channel in membrane microdomains of human cancer cells.

Biochim Biophys Acta Mol Basis Dis 2018 11 13;1864(11):3792-3804. Epub 2018 Sep 13.

Department of Pharmaceutical Physiology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194, Japan. Electronic address:

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November 2018

Syncytium calcium signaling and macrophage function in the heart.

Cell Biosci 2018 27;8:24. Epub 2018 Mar 27.

1Laboratory of Cell Biology, Genetics and Developmental Biology, Shaanxi Normal University College of Life Sciences, Xi'an, 710062 People's Republic of China.

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March 2018

Negative regulation of cellular Ca mobilization by ryanodine receptor type 3 in mouse mesenteric artery smooth muscle.

Am J Physiol Cell Physiol 2018 07 14;315(1):C1-C9. Epub 2018 Mar 14.

Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University , Nagoya , Japan.

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July 2018

The natural flavonoid myricetin inhibits gastric H, K-ATPase.

Eur J Pharmacol 2018 Feb 20;820:217-221. Epub 2017 Dec 20.

Department of Biological Chemistry Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto 606-8501, Japan. Electronic address:

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February 2018

[Excitation-contraction coupling and junctional membrane structures.]

Clin Calcium 2017;27(3):333-338

Graduate School of Pharmaceutical Sciences, Kyoto University, Japan.

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October 2017

Ryanodine receptor type 3 does not contribute to contractions in the mouse myometrium regardless of pregnancy.

Pflugers Arch 2017 02 20;469(2):313-326. Epub 2016 Nov 20.

Department of Molecular and Cellular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya City University, Nagoya, 467-8603, Japan.

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February 2017

TRIC-B Mutations Causing Osteogenesis Imperfecta.

Biol Pharm Bull 2016 ;39(11):1743-1747

Graduate School of Pharmaceutical Sciences, Kyoto University.

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January 2017