Hiroshi Ohno

Hiroshi Ohno

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Hiroshi Ohno

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Soluble CD14 in Breast Milk and Its Relation to Atopic Manifestations in Early Infancy.

Nutrients 2019 Sep 5;11(9). Epub 2019 Sep 5.

Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba 2608670, Japan.

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http://dx.doi.org/10.3390/nu11092118DOI Listing
September 2019

Probiotic Bifidobacterium bifidum G9-1 ameliorates phytohemagglutinin-induced diarrhea caused by intestinal dysbiosis.

Microbiol Immunol 2019 Sep 23. Epub 2019 Sep 23.

R&D Center, Biofermin Pharmaceutical Co., Kobe, Hyogo, Japan.

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http://dx.doi.org/10.1111/1348-0421.12743DOI Listing
September 2019

Dynamic Balance Measurements Can Differentiate Patients Who Fall From Patients Who Do Not Fall in Patients With Idiopathic Normal Pressure Hydrocephalus.

Arch Phys Med Rehabil 2019 Aug 4;100(8):1458-1466. Epub 2019 Feb 4.

Department of Physical and Rehabilitation Medicine, Division of Comprehensive Medicine, Osaka Medical College, Osaka, Japan.

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http://dx.doi.org/10.1016/j.apmr.2019.01.008DOI Listing
August 2019

Lactobacillus sp. improved microbiota and metabolite profiles of aging rats.

Pharmacol Res 2019 Aug 14;146:104312. Epub 2019 Jun 14.

School of Industrial Technology, Universiti Sains Malaysia, 11800, Penang, Malaysia; USM-RIKEN International Centre for Ageing Science (URICAS), Universiti Sains Malaysia, 11800 USM, Penang, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2019.104312DOI Listing
August 2019

Associations among falls, gait variability, and balance function in idiopathic normal pressure hydrocephalus.

Clin Neurol Neurosurg 2019 Aug 10;183:105385. Epub 2019 Jun 10.

Department of Physical and Rehabilitation Medicine, Division of Comprehensive Medicine, Osaka Medical College, Osaka, Japan.

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http://dx.doi.org/10.1016/j.clineuro.2019.105385DOI Listing
August 2019

Extracellular transglycosylase and glyceraldehyde-3-phosphate dehydrogenase attributed to the anti-staphylococcal activity of Lactobacillus plantarum USM8613.

J Biotechnol 2019 Jul 13;300:20-31. Epub 2019 May 13.

School of Industrial Technology, Universiti Sains Malaysia, 11800, Penang, Malaysia; USM-RIKEN International Centre for Ageing Science (URICAS), Universiti Sains Malaysia, 11800, Penang, Malaysia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01681656193016
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http://dx.doi.org/10.1016/j.jbiotec.2019.05.006DOI Listing
July 2019

Innate Lymphoid Cells in the Induction of Obesity.

Cell Rep 2019 Jul;28(1):202-217.e7

Laboratory for Immune Cell Systems, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan; Deparment of Microbiology and Immunology, Keio University School of Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.06.016DOI Listing
July 2019

Gradient-index dark hole based on conformal mapping with etendue conservation.

Opt Express 2019 Jun;27(13):18493-18507

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http://dx.doi.org/10.1364/OE.27.018493DOI Listing
June 2019

Maternal gut microbiota is associated with newborn anthropometrics in a sex-specific manner.

J Dev Orig Health Dis 2019 May 20:1-8. Epub 2019 May 20.

Center for Preventive Medical Sciences,Chiba University,Chiba,Japan.

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http://dx.doi.org/10.1017/S2040174419000138DOI Listing
May 2019

Multi-angle-view monocular camera using a polarization image sensor.

Authors:
Hiroshi Ohno

Appl Opt 2019 May;58(15):4036-4041

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http://dx.doi.org/10.1364/AO.58.004036DOI Listing
May 2019

Assessment of the cost effectiveness of compulsory testing of introduced animals and bulk tank milk testing for bovine viral diarrhea in Japan.

J Vet Med Sci 2019 Apr 1;81(4):577-585. Epub 2019 Mar 1.

Global Station for Zoonosis Control, Global Institute for Collaborative Research and Education (GI-CoRE), Hokkaido University, Sapporo, Hokkaido 001-0020, Japan.

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http://dx.doi.org/10.1292/jvms.18-0671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483914PMC
April 2019

Role of the IgM Fc Receptor in Immunity and Tolerance.

Front Immunol 2019 22;10:529. Epub 2019 Mar 22.

Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China.

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00529
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http://dx.doi.org/10.3389/fimmu.2019.00529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438924PMC
March 2019

Total internal reflection shell for light-emitting diode bulbs.

Appl Opt 2019 Jan;58(1):87-93

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http://dx.doi.org/10.1364/AO.58.000087DOI Listing
January 2019

Lactobacillus plantarum USM8613 Aids in Wound Healing and Suppresses Staphylococcus aureus Infection at Wound Sites.

Probiotics Antimicrob Proteins 2019 Jan 18. Epub 2019 Jan 18.

School of Industrial Technology, Universiti Sains Malaysia, 11800, Penang, Malaysia.

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http://dx.doi.org/10.1007/s12602-018-9505-9DOI Listing
January 2019

Oral Administration of Porphyromonas gingivalis Alters the Gut Microbiome and Serum Metabolome.

mSphere 2018 10 17;3(5). Epub 2018 Oct 17.

Research Unit for Oral-Systemic Connection, Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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http://msphere.asm.org/lookup/doi/10.1128/mSphere.00460-18
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http://dx.doi.org/10.1128/mSphere.00460-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193602PMC
October 2018

Depth reconstruction with coaxial multi-wavelength aperture telecentric optical system.

Opt Express 2018 Oct;26(20):25880-25891

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http://dx.doi.org/10.1364/OE.26.025880DOI Listing
October 2018

Postural control before and after cerebrospinal fluid shunt surgery in idiopathic normal pressure hydrocephalus.

Clin Neurol Neurosurg 2018 09 30;172:46-50. Epub 2018 Jun 30.

Department of Physical and Rehabilitation Medicine, Division of Comprehensive Medicine, Osaka Medical College, Osaka, Japan.

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http://dx.doi.org/10.1016/j.clineuro.2018.06.032DOI Listing
September 2018

The Peroxisome Proliferator-Activated Receptor α (PPARα) Agonist Pemafibrate Protects against Diet-Induced Obesity in Mice.

Int J Mol Sci 2018 Jul 23;19(7). Epub 2018 Jul 23.

Department of Internal Medicine (Endocrinology and Metabolism), Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan.

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http://dx.doi.org/10.3390/ijms19072148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073532PMC
July 2018

The effect of CSF drainage on ambulatory center of mass movement in idiopathic normal pressure hydrocephalus.

Gait Posture 2018 06 21;63:5-9. Epub 2018 Apr 21.

Department of Physical and Rehabilitation Medicine, Division of Comprehensive Medicine, Osaka Medical College, Osaka, Japan.

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http://dx.doi.org/10.1016/j.gaitpost.2018.04.024DOI Listing
June 2018

Postural instability differences between idiopathic normal pressure hydrocephalus and Parkinson's disease.

Clin Neurol Neurosurg 2018 02 10;165:103-107. Epub 2018 Jan 10.

Department of Physical and Rehabilitation Medicine, Division of Comprehensive Medicine, Osaka Medical College, Osaka, Japan.

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http://dx.doi.org/10.1016/j.clineuro.2018.01.012DOI Listing
February 2018

Lactobacillus fermentum FTDC 8312 combats hypercholesterolemia via alteration of gut microbiota.

J Biotechnol 2017 Nov 19;262:75-83. Epub 2017 Sep 19.

School of Industrial Technology, Universiti Sains Malaysia, 11800 Penang, Malaysia; USM-RIKEN International Centre for Ageing Science (URICAS), Universiti Sains Malaysia, 11800 USM, Penang, Malaysia. Electronic address:

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http://dx.doi.org/10.1016/j.jbiotec.2017.09.007DOI Listing
November 2017

Distinct Roles for CXCR6(+) and CXCR6(-) CD4(+) T Cells in the Pathogenesis of Chronic Colitis.

PLoS One 2013 19;8(6):e65488. Epub 2013 Jun 19.

Department of Clinical Cell Biology, Graduate School of Medicine, Chiba University, Chiba, Japan ; Laboratory for Epithelial Immunobiology, Research Center for Allergy and Immunology, RIKEN Yokohama Institute, Yokohama, Kanagawa, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0065488PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686755PMC
October 2017

Intestinal IgA as a modulator of the gut microbiota.

Gut Microbes 2017 09 6;8(5):486-492. Epub 2017 Apr 6.

a Applied Immunology , Nara Institute of Science and Technology , Nara , Japan.

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http://dx.doi.org/10.1080/19490976.2017.1310357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5628655PMC
September 2017

FANTOM5 CAGE profiles of human and mouse samples.

Authors:
Shuhei Noguchi Takahiro Arakawa Shiro Fukuda Masaaki Furuno Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Kaoru Kaida Ai Kaiho Mutsumi Kanamori-Katayama Tsugumi Kawashima Miki Kojima Atsutaka Kubosaki Ri-Ichiroh Manabe Mitsuyoshi Murata Sayaka Nagao-Sato Kenichi Nakazato Noriko Ninomiya Hiromi Nishiyori-Sueki Shohei Noma Eri Saijyo Akiko Saka Mizuho Sakai Christophe Simon Naoko Suzuki Michihira Tagami Shoko Watanabe Shigehiro Yoshida Peter Arner Richard A Axton Magda Babina J Kenneth Baillie Timothy C Barnett Anthony G Beckhouse Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher Ailsa J Carlisle Hans C Clevers Carrie A Davis Michael Detmar Taeko Dohi Albert S B Edge Matthias Edinger Anna Ehrlund Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Mary C Farach-Carson Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley M Forrester Rie Fujita Jun-Ichi Furusawa Teunis B Geijtenbeek Thomas Gingeras Daniel Goldowitz Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Yuki Hasegawa Meenhard Herlyn Peter Heutink Kelly J Hitchens David A Hume Tomokatsu Ikawa Yuri Ishizu Chieko Kai Hiroshi Kawamoto Yuki I Kawamura Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura Sarah Klein S Peter Klinken Alan J Knox Soichi Kojima Haruhiko Koseki Shigeo Koyasu Weonju Lee Andreas Lennartsson Alan Mackay-Sim Niklas Mejhert Yosuke Mizuno Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Kelly J Morris Hozumi Motohashi Christine L Mummery Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Tadasuke Nozaki Soichi Ogishima Naganari Ohkura Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Swati Pradhan-Bhatt Xian-Yang Qin Michael Rehli Patrizia Rizzu Sugata Roy Antti Sajantila Shimon Sakaguchi Hiroki Sato Hironori Satoh Suzana Savvi Alka Saxena Christian Schmidl Claudio Schneider Gundula G Schulze-Tanzil Anita Schwegmann Guojun Sheng Jay W Shin Daisuke Sugiyama Takaaki Sugiyama Kim M Summers Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Andru Tomoiu Hiroo Toyoda Marc van de Wetering Linda M van den Berg Roberto Verardo Dipti Vijayan Christine A Wells Louise N Winteringham Ernst Wolvetang Yoko Yamaguchi Masayuki Yamamoto Chiyo Yanagi-Mizuochi Misako Yoneda Yohei Yonekura Peter G Zhang Silvia Zucchelli Imad Abugessaisa Erik Arner Jayson Harshbarger Atsushi Kondo Timo Lassmann Marina Lizio Serkan Sahin Thierry Sengstag Jessica Severin Hisashi Shimoji Masanori Suzuki Harukazu Suzuki Jun Kawai Naoto Kondo Masayoshi Itoh Carsten O Daub Takeya Kasukawa Hideya Kawaji Piero Carninci Alistair R R Forrest Yoshihide Hayashizaki

Sci Data 2017 08 29;4:170112. Epub 2017 Aug 29.

RIKEN Omics Science Center, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/sdata.2017.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574368PMC
August 2017

Uromodulin-SlpA binding dictates Lactobacillus acidophilus uptake by intestinal epithelial M cells.

Int Immunol 2017 08;29(8):357-363

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1093/intimm/dxx043DOI Listing
August 2017

Evaluation of control measures for bovine viral diarrhea implemented in Nemuro District, Hokkaido, Japan, using a scenario tree model.

J Vet Med Sci 2017 Jul 25;79(7):1172-1181. Epub 2017 May 25.

Global Station for Zoonosis Control, Global Institute for Collaborative Research and Education (GI-CoRE), Hokkaido University, Kita 20, Nishi 10, Kita-ku, Sapporo, Hokkaido 001-0020, Japan.

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http://dx.doi.org/10.1292/jvms.17-0108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5559360PMC
July 2017

Understanding the immune signature fingerprint of peritoneal dialysis-related peritonitis.

Kidney Int 2017 07;92(1):16-18

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2017.02.027DOI Listing
July 2017

Aggravation of collagen-induced arthritis by orally administered Porphyromonas gingivalis through modulation of the gut microbiota and gut immune system.

Sci Rep 2017 07 31;7(1):6955. Epub 2017 Jul 31.

Research Unit for Oral-Systemic Connection, Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://dx.doi.org/10.1038/s41598-017-07196-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5537233PMC
July 2017

IL-22BP dictates characteristics of Peyer's patch follicle-associated epithelium for antigen uptake.

J Exp Med 2017 06 16;214(6):1607-1618. Epub 2017 May 16.

Laboratory for Intestinal Ecosystem, Center for Integrative Medical Sciences, Institute of Physical and Chemical Research, Yokohama 230-0045, Japan

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http://dx.doi.org/10.1084/jem.20160770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460992PMC
June 2017

Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections.

Immunity 2017 05;46(5):863-874.e4

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa 230-0045, Japan; Division of Immunobiology, Department of Medical Life Science, Graduate School of Medical Life Science, Yokohama City University, Kanagawa 230-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.04.017DOI Listing
May 2017

Design of a coaxial light guide producing a wide-angle light distribution.

Authors:
Hiroshi Ohno

Appl Opt 2017 May;56(14):3977-3983

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http://dx.doi.org/10.1364/AO.56.003977DOI Listing
May 2017

Midterm outcomes of high-flexion total knee arthroplasty on Japanese lifestyle.

Acta Orthop Traumatol Turc 2016 Oct 24;50(5):527-532. Epub 2016 Sep 24.

Kansai Medical University, Osaka, Japan.

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http://dx.doi.org/10.1016/j.aott.2016.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197585PMC
October 2016

Distinct Roles for the N- and C-terminal Regions of M-Sec in Plasma Membrane Deformation during Tunneling Nanotube Formation.

Sci Rep 2016 09 15;6:33548. Epub 2016 Sep 15.

Structural Biology Laboratory, Life Science Division, Synchrotron Radiation Research Organization and Institute of Molecular and Cellular Biosciences, The University of Tokyo, Tokyo 113-0032, Japan.

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http://dx.doi.org/10.1038/srep33548DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5024327PMC
September 2016

Actions of probiotics on trinitrobenzenesulfonic acid-induced colitis in rats.

Biomed Res Int 2015 13;2015:528523. Epub 2015 Oct 13.

Department of Basic Veterinary Science, Laboratory of Physiology, The United Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.

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http://dx.doi.org/10.1155/2015/528523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4621330PMC
August 2016

Oral Administration of P. gingivalis Induces Dysbiosis of Gut Microbiota and Impaired Barrier Function Leading to Dissemination of Enterobacteria to the Liver.

PLoS One 2015 28;10(7):e0134234. Epub 2015 Jul 28.

Laboratory of Periodontology and Immunology, Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134234PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4517782PMC
May 2016

Reduced Human α-defensin 6 in Noninflamed Jejunal Tissue of Patients with Crohn's Disease.

Inflamm Bowel Dis 2016 May;22(5):1119-28

*Department of Gastroenterology and Metabolism, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan; †Department of Gastroenterology and Hepatology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan; ‡Department of Pathology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan; §Department of Endoscopic Diagnosis and Therapy, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan; ‖Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences (IMS) AMEDCREST, Japan Agency for Medical Research and Development, Yokohama, Japan; ¶Institute for Advanced Biosciences, Keio University, Tsuruoka, Japan; **Center for Stem Cell and Regenerative Medicine and Graduate School, Tokyo Medical and Dental University, Tokyo, Japan; ††Department of Advanced Therapeutics for Gastrointestinal Diseases, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan; and ‡‡Endoscopy and Medicine, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.

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http://dx.doi.org/10.1097/MIB.0000000000000707DOI Listing
May 2016

Intestinal M cells.

Authors:
Hiroshi Ohno

J Biochem 2016 Feb 3;159(2):151-60. Epub 2015 Dec 3.

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, 1-7-22 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan

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http://dx.doi.org/10.1093/jb/mvv121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892784PMC
February 2016

Potential Role of the Formation of Tunneling Nanotubes in HIV-1 Spread in Macrophages.

J Immunol 2016 Feb 15;196(4):1832-41. Epub 2016 Jan 15.

Center for AIDS Research, International Research Center for Medical Sciences, Kumamoto University, Kumamoto, Kumamoto 860-0811, Japan;

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http://dx.doi.org/10.4049/jimmunol.1500845DOI Listing
February 2016

sp. nov., isolated from the caeca of gnotobiotic mice fed with thermophile-fermented compost.

Int J Syst Evol Microbiol 2015 Nov 12;65(11):3944-3949. Epub 2015 Aug 12.

1​Graduate School of Advanced Integration Science, Chiba University, 1-33 Yayoi-cho, Inage-ku, Chiba 263-8522, Japan.

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http://dx.doi.org/10.1099/ijsem.0.000516DOI Listing
November 2015

Longitudinal study of effects of oral dosage of Bifidobacterium bifidum G9-1 on Japanese cedar pollen-induced allergic nasal symptoms in guinea pigs.

Microbiol Immunol 2015 Nov;59(11):690-9

Laboratory of Immunopharmacology, Faculty of Pharmaceutical Sciences, Setsunan University, 45-1 Nagaotoge-cho, Hirakata, Osaka, 573-0101.

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http://dx.doi.org/10.1111/1348-0421.12324DOI Listing
November 2015

[Gut microbiota, host defense and immunity: analysis with integrative omics approach].

Authors:
Hiroshi Ohno

Nihon Rinsho Meneki Gakkai Kaishi 2014 ;37(5):403-11

RIKEN Center for Integrative Medical Sciences.

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http://dx.doi.org/10.2177/jsci.37.403DOI Listing
October 2015

Th17 Cell Induction by Adhesion of Microbes to Intestinal Epithelial Cells.

Cell 2015 Oct 24;163(2):367-80. Epub 2015 Sep 24.

RIKEN Center for Integrative Medical Sciences (IMS), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan; Department of Microbiology and Immunology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan; CREST, JST, 4-1-8 Honcho Kawaguchi, Saitama 332-0012, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.08.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765954PMC
October 2015

Distinct microRNA expression profiles in follicle-associated epithelium and villous epithelium.

Genom Data 2015 Sep 15;5:388-90. Epub 2015 Jul 15.

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences (IMS), Kanagawa, Japan ; AMED-CREST, Japan Agency for Medical Research and Development, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.gdata.2015.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583698PMC
September 2015

Nomenclature of Toso, Fas apoptosis inhibitory molecule 3, and IgM FcR.

J Immunol 2015 May;194(9):4055-7

Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852;

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http://dx.doi.org/10.4049/jimmunol.1500222DOI Listing
May 2015

Botulinum toxin A complex exploits intestinal M cells to enter the host and exert neurotoxicity.

Nat Commun 2015 Feb 17;6:6255. Epub 2015 Feb 17.

Laboratory for Infection Cell Biology, International Research Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, 3-1, Yamada-oka, Suita, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1038/ncomms7255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339894PMC
February 2015

[Impact of gut microbiota on host physiology and pathology].

Authors:
Hiroshi Ohno

Nihon Shokakibyo Gakkai Zasshi 2015 Feb;112(2):264-9

RIKEN Center for Integrative Medical Sciences.

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http://dx.doi.org/10.11405/nisshoshi.112.264DOI Listing
February 2015

Impact of commensal microbiota on the host pathophysiology: focusing on immunity and inflammation.

Authors:
Hiroshi Ohno

Semin Immunopathol 2015 Jan 9;37(1):1-3. Epub 2014 Dec 9.

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, 230-0045, Japan,

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http://link.springer.com/content/pdf/10.1007/s00281-014-0472
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http://link.springer.com/10.1007/s00281-014-0472-2
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http://dx.doi.org/10.1007/s00281-014-0472-2DOI Listing
January 2015

Enhanced auto-antibody production and Mott cell formation in FcμR-deficient autoimmune mice.

Int Immunol 2014 Dec 3;26(12):659-72. Epub 2014 Jul 3.

Department of Pathology, University of Alabama at Birmingham, Birmingham, AL 35294, USA

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http://dx.doi.org/10.1093/intimm/dxu070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4242241PMC
December 2014

Epithelial-stromal interaction via Notch signaling is essential for the full maturation of gut-associated lymphoid tissues.

EMBO Rep 2014 Dec 5;15(12):1297-304. Epub 2014 Nov 5.

Department of Immune Regulation, Graduate School of Medical and Pharmaceutical Sciences Chiba University, Chiba, Japan Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

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http://dx.doi.org/10.15252/embr.201438942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4264932PMC
December 2014

Pitfalls in global normalization of ChIP-seq data in CD4(+) T cells treated with butyrate: A possible solution strategy.

Genom Data 2014 Dec 27;2:176-80. Epub 2014 Jun 27.

Graduate School of Pharmaceutical Science, Keio University, Tokyo 105-8512, Japan ; The Institute of Medical Science, The University of Tokyo, Tokyo 108 8639, Japan ; RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Kanagawa 230 0045, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S22135960140005
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http://dx.doi.org/10.1016/j.gdata.2014.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536162PMC
December 2014

A novel mucosal vaccine targeting Peyer's patch M cells induces protective antigen-specific IgA responses.

Int Immunol 2014 Nov 7;26(11):619-25. Epub 2014 Jun 7.

Division of Immunobiology, Graduate School of Supramolecular Biology, Yokohama City University, Yokohama, Kanagawa 230-0045, Japan Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa 230-0045, Japan

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http://dx.doi.org/10.1093/intimm/dxu061DOI Listing
November 2014

Lactobacillus acidophilus L-92 Cells Activate Expression of Immunomodulatory Genes in THP-1 Cells.

Biosci Microbiota Food Health 2014 1;33(4):157-64. Epub 2014 Aug 1.

Intestinal Microbe Symbiosis Laboratory, RIKEN, Wako, Saitama 351-0198, Japan ; Research and Development Planning Department, Calpis Co. Ltd., 5-11-10 Fuchinobe, Chuo-ku, Sagamihara-shi, Kanagawa 252-0206, Japan.

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http://dx.doi.org/10.12938/bmfh.33.157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4219982PMC
November 2014

The Role of the Clathrin Adaptor AP-1: Polarized Sorting and Beyond.

Membranes (Basel) 2014 Nov 7;4(4):747-63. Epub 2014 Nov 7.

RIKEN Center for Integrative Medical Sciences (IMS), Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.3390/membranes4040747DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4289864PMC
November 2014

Selection of an aptamer against mouse GP2 by SELEX.

Cell Struct Funct 2014 12;39(1):23-9. Epub 2013 Dec 12.

Laboratory for Intestinal Ecosystem, RCAI, RIKEN Center for Integrative Medical Sciences (IMS-RCAI).

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http://dx.doi.org/10.1247/csf.13019DOI Listing
October 2014

Multiple omics uncovers host-gut microbial mutualism during prebiotic fructooligosaccharide supplementation.

DNA Res 2014 Oct 19;21(5):469-80. Epub 2014 May 19.

Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences (IMS), 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan Graduate School of Medical Life Science, Yokohama City University, Kanagawa 230-0045, Japan

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http://dx.doi.org/10.1093/dnares/dsu013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195493PMC
October 2014

In vitro evaluation method for screening of candidate prebiotic foods.

Food Chem 2014 1;152:251-60. Epub 2013 Dec 1.

RIKEN Center for Sustainable Resource Science, 1-7-22 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan; Graduate School of Medical Life Science, Yokohama City University, 1-7-29 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan; Graduate School of Bioagricultural Sciences, Nagoya University, 1 Furo-cho, Chikusa-ku, Nagoya, Aichi 464-0810, Japan; Biomass Engineering Program, RIKEN Research Cluster for Innovation, 1-7-22 Suehirocho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.foodchem.2013.11.126DOI Listing
September 2014

Bifidobacterium longum alleviates dextran sulfate sodium-induced colitis by suppressing IL-17A response: involvement of intestinal epithelial costimulatory molecules.

PLoS One 2013 8;8(11):e79735. Epub 2013 Nov 8.

Graduate School of Biosphere Science, Hiroshima University, Higashi-Hiroshima, Hiroshima, Japan ; Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Yokohama, Kanagawa, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0079735PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3821848PMC
July 2014

The Mechanisms of M-cell Differentiation.

Biosci Microbiota Food Health 2014 9;33(3):91-7. Epub 2014 May 9.

Laboratory for Intestinal Ecosystem, RCAI, Riken Center for Integrative Medical Sciences (IMS-RCAI), 1-7-22 Suehiro-cho, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.

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https://www.jstage.jst.go.jp/article/bmfh/33/3/33_2013-024/_
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http://dx.doi.org/10.12938/bmfh.33.91DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4098651PMC
July 2014

The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells.

Nat Immunol 2014 Jun 28;15(6):571-9. Epub 2014 Apr 28.

1] Division of Mucosal Barriology, International Research and Development Center for Mucosal Vaccines, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan. [2] Laboratory for Bioenvironmental Epigenetics, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan. [3] Graduate School of Medical Life Science, Yokohama City University, Kanagawa, Japan. [4] PRESTO, Japan Science and Technology Agency, Saitama, Japan. [5].

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http://dx.doi.org/10.1038/ni.2886DOI Listing
June 2014

A promoter-level mammalian expression atlas.

Authors:
Alistair R R Forrest Hideya Kawaji Michael Rehli J Kenneth Baillie Michiel J L de Hoon Vanja Haberle Timo Lassmann Ivan V Kulakovskiy Marina Lizio Masayoshi Itoh Robin Andersson Christopher J Mungall Terrence F Meehan Sebastian Schmeier Nicolas Bertin Mette Jørgensen Emmanuel Dimont Erik Arner Christian Schmidl Ulf Schaefer Yulia A Medvedeva Charles Plessy Morana Vitezic Jessica Severin Colin A Semple Yuri Ishizu Robert S Young Margherita Francescatto Intikhab Alam Davide Albanese Gabriel M Altschuler Takahiro Arakawa John A C Archer Peter Arner Magda Babina Sarah Rennie Piotr J Balwierz Anthony G Beckhouse Swati Pradhan-Bhatt Judith A Blake Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher A Maxwell Burroughs Andrea Califano Carlo V Cannistraci Daniel Carbajo Yun Chen Marco Chierici Yari Ciani Hans C Clevers Emiliano Dalla Carrie A Davis Michael Detmar Alexander D Diehl Taeko Dohi Finn Drabløs Albert S B Edge Matthias Edinger Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Michela Fagiolini Lynsey Fairbairn Hai Fang Mary C Farach-Carson Geoffrey J Faulkner Alexander V Favorov Malcolm E Fisher Martin C Frith Rie Fujita Shiro Fukuda Cesare Furlanello Masaaki Furino Jun-ichi Furusawa Teunis B Geijtenbeek Andrew P Gibson Thomas Gingeras Daniel Goldowitz Julian Gough Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Matthias Harbers Jayson Harshbarger Akira Hasegawa Yuki Hasegawa Takehiro Hashimoto Meenhard Herlyn Kelly J Hitchens Shannan J Ho Sui Oliver M Hofmann Ilka Hoof Furni Hori Lukasz Huminiecki Kei Iida Tomokatsu Ikawa Boris R Jankovic Hui Jia Anagha Joshi Giuseppe Jurman Bogumil Kaczkowski Chieko Kai Kaoru Kaida Ai Kaiho Kazuhiro Kajiyama Mutsumi Kanamori-Katayama Artem S Kasianov Takeya Kasukawa Shintaro Katayama Sachi Kato Shuji Kawaguchi Hiroshi Kawamoto Yuki I Kawamura Tsugumi Kawashima Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura S Peter Klinken Alan J Knox Miki Kojima Soichi Kojima Naoto Kondo Haruhiko Koseki Shigeo Koyasu Sarah Krampitz Atsutaka Kubosaki Andrew T Kwon Jeroen F J Laros Weonju Lee Andreas Lennartsson Kang Li Berit Lilje Leonard Lipovich Alan Mackay-Sim Ri-ichiroh Manabe Jessica C Mar Benoit Marchand Anthony Mathelier Niklas Mejhert Alison Meynert Yosuke Mizuno David A de Lima Morais Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Efthymios Motakis Hozumi Motohashi Christine L Mummery Mitsuyoshi Murata Sayaka Nagao-Sato Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Kenichi Nakazato Erik van Nimwegen Noriko Ninomiya Hiromi Nishiyori Shohei Noma Shohei Noma Tadasuke Noazaki Soichi Ogishima Naganari Ohkura Hiroko Ohimiya Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Arnab Pain Robert Passier Margaret Patrikakis Helena Persson Silvano Piazza James G D Prendergast Owen J L Rackham Jordan A Ramilowski Mamoon Rashid Timothy Ravasi Patrizia Rizzu Marco Roncador Sugata Roy Morten B Rye Eri Saijyo Antti Sajantila Akiko Saka Shimon Sakaguchi Mizuho Sakai Hiroki Sato Suzana Savvi Alka Saxena Claudio Schneider Erik A Schultes Gundula G Schulze-Tanzil Anita Schwegmann Thierry Sengstag Guojun Sheng Hisashi Shimoji Yishai Shimoni Jay W Shin Christophe Simon Daisuke Sugiyama Takaai Sugiyama Masanori Suzuki Naoko Suzuki Rolf K Swoboda Peter A C 't Hoen Michihira Tagami Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Zuotian Tatum Mark Thompson Hiroo Toyodo Tetsuro Toyoda Elvind Valen Marc van de Wetering Linda M van den Berg Roberto Verado Dipti Vijayan Ilya E Vorontsov Wyeth W Wasserman Shoko Watanabe Christine A Wells Louise N Winteringham Ernst Wolvetang Emily J Wood Yoko Yamaguchi Masayuki Yamamoto Misako Yoneda Yohei Yonekura Shigehiro Yoshida Susan E Zabierowski Peter G Zhang Xiaobei Zhao Silvia Zucchelli Kim M Summers Harukazu Suzuki Carsten O Daub Jun Kawai Peter Heutink Winston Hide Tom C Freeman Boris Lenhard Vladimir B Bajic Martin S Taylor Vsevolod J Makeev Albin Sandelin David A Hume Piero Carninci Yoshihide Hayashizaki

Nature 2014 Mar;507(7493):462-70

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http://dx.doi.org/10.1038/nature13182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529748PMC
March 2014

Gut microbiome and metabolic diseases.

Semin Immunopathol 2014 Jan 6;36(1):103-14. Epub 2013 Nov 6.

Institute for Advanced Biosciences, Keio University, 246-2 Mizukami, Kakuganji, Tsuruoka, Yamagata, 997-0052, Japan.

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http://link.springer.com/10.1007/s00281-013-0399-z
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http://dx.doi.org/10.1007/s00281-013-0399-zDOI Listing
January 2014

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells.

Nature 2013 Dec 13;504(7480):446-50. Epub 2013 Nov 13.

1] RIKEN Center for Integrative Medical Sciences (IMS-RCAI), Kanagawa 230-0045, Japan [2] Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan [3] Graduate School of Medical Life Science, Yokohama City University, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/nature12721DOI Listing
December 2013

Microbiota-derived lactate accelerates colon epithelial cell turnover in starvation-refed mice.

Nat Commun 2013 ;4:1654

Department of Gastroenterology, Research Center for Hepatitis and Immunology, Research Institute, National Center for Global Health and Medicine, 1-7-1 Kohnodai, Ichikawa, Chiba 272-8516, Japan.

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http://dx.doi.org/10.1038/ncomms2668DOI Listing
October 2013

Robustness of gut microbiota of healthy adults in response to probiotic intervention revealed by high-throughput pyrosequencing.

DNA Res 2013 Jun 9;20(3):241-53. Epub 2013 Apr 9.

Center for Omics and Bioinformatics, The Department of Computational Biology, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwanoha 5-1-5, Kashiwa, Chiba 277-8561, Japan.

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http://dx.doi.org/10.1093/dnares/dst006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3686430PMC
June 2013