Publications by authors named "Hiroshi Nagasaki"

62Publications

The alpha-glucosidase inhibitor miglitol increases hepatic CYP7A1 activity in association with altered short-chain fatty acid production in the gut of obese diabetic mice.

Metabol Open 2020 Mar 11;5:100024. Epub 2020 Jan 11.

Division of Diabetes, Department of Internal Medicine, Aichi Medical University School of Medicine, 1-1 Yazakokarimata, Nagakute, 480-1195, Japan.

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http://dx.doi.org/10.1016/j.metop.2020.100024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7424806PMC
March 2020

NT5DC2 affects the phosphorylation of tyrosine hydroxylase regulating its catalytic activity.

J Neural Transm (Vienna) 2020 Aug 10. Epub 2020 Aug 10.

Department Physiology, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1007/s00702-020-02236-5DOI Listing
August 2020

Identification by nano-LC-MS/MS of NT5DC2 as a protein binding to tyrosine hydroxylase: Down-regulation of NT5DC2 by siRNA increases catecholamine synthesis in PC12D cells.

Biochem Biophys Res Commun 2019 09 3;516(4):1060-1065. Epub 2019 Jul 3.

Department Physiology, Fujita Health University, School of Medicine, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2019.06.156DOI Listing
September 2019

Proteasome-mediated degradation of tyrosine hydroxylase triggered by its phosphorylation: a new question as to the intracellular location at which the degradation occurs.

J Neural Transm (Vienna) 2018 01 19;125(1):9-15. Epub 2016 Nov 19.

Department of Physiology, Fujita Health University School of Medicine, Toyoake, 470-1192, Aichi, Japan.

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http://dx.doi.org/10.1007/s00702-016-1653-zDOI Listing
January 2018

Recombinant human thrombomodulin inhibits neutrophil extracellular trap formation in vitro.

J Intensive Care 2016 22;4:48. Epub 2016 Jul 22.

Department of Anesthesiology and Critical Care Medicine, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, Aichi 470-1192 Japan.

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http://dx.doi.org/10.1186/s40560-016-0177-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957921PMC
July 2016

Inhibition of deubiquitinating activity of USP14 decreases tyrosine hydroxylase phosphorylated at Ser19 in PC12D cells.

Biochem Biophys Res Commun 2016 Apr 8;472(4):598-602. Epub 2016 Mar 8.

Department of Physiology, School of Medicine, Fujita Health University, Toyoake, Aichi, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2016.03.022DOI Listing
April 2016

Aripiprazole increases NAD(P)H-quinone oxidoreductase-1 and heme oxygenase-1 in PC12 cells.

J Neural Transm (Vienna) 2015 Jun 14;122(6):757-72. Epub 2014 Dec 14.

Department of Physiology, Fujita Health University School of Medicine, Toyoake, 470-1192, Japan.

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http://dx.doi.org/10.1007/s00702-014-1350-8DOI Listing
June 2015

Involvement of de novo ceramide synthesis in pro-inflammatory adipokine secretion and adipocyte-macrophage interaction.

J Nutr Biochem 2014 Dec 19;25(12):1309-16. Epub 2014 Sep 19.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, 65 Tsuruma-cho, Showa-ku, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1016/j.jnutbio.2014.07.008DOI Listing
December 2014

Lipopolysaccharide treatment arrests the cell cycle of BV-2 microglial cells in G₁ phase and protects them from UV light-induced apoptosis.

J Neural Transm (Vienna) 2015 Feb 12;122(2):187-99. Epub 2014 Jun 12.

Department of Physiology, Fujita Health University School of Medicine, 1-98 Dengakugakubo, Kutsukake-cho, Toyoake, 470-1192, Japan,

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http://dx.doi.org/10.1007/s00702-014-1256-5DOI Listing
February 2015

Intracellular stability of tyrosine hydroxylase: phosphorylation and proteasomal digestion of the enzyme.

Adv Pharmacol 2013 ;68:3-11

Department of Physiology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan. Electronic address:

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http://dx.doi.org/10.1016/B978-0-12-411512-5.00001-4DOI Listing
May 2014

Aripiprazole increases NADPH level in PC12 cells: the role of NADPH oxidase.

J Neural Transm (Vienna) 2014 Jan 10;121(1):91-103. Epub 2013 Aug 10.

Department of Physiology, Fujita Health University School of Medicine, Toyoake, 470-1192, Japan.

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http://dx.doi.org/10.1007/s00702-013-1075-0DOI Listing
January 2014

The role of S100B in the interaction between adipocytes and macrophages.

Obesity (Silver Spring) 2014 Feb 19;22(2):371-9. Epub 2013 Aug 19.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1002/oby.20532DOI Listing
February 2014

Two WUSCHEL-related homeobox genes, narrow leaf2 and narrow leaf3, control leaf width in rice.

Plant Cell Physiol 2013 May 18;54(5):779-92. Epub 2013 Feb 18.

Department of Biological Mechanisms and Functions, Graduate School of Bioagricultural Sciences, Nagoya University, Nagoya, 464-8601 Japan.

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http://dx.doi.org/10.1093/pcp/pct032DOI Listing
May 2013

The alpha-glucosidase inhibitor miglitol affects bile acid metabolism and ameliorates obesity and insulin resistance in diabetic mice.

Metabolism 2013 May 26;62(5):734-42. Epub 2012 Nov 26.

Department of Metabolic Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://dx.doi.org/10.1016/j.metabol.2012.10.015DOI Listing
May 2013

A possible pathophysiological role of tyrosine hydroxylase in Parkinson's disease suggested by postmortem brain biochemistry: a contribution for the special 70th birthday symposium in honor of Prof. Peter Riederer.

J Neural Transm (Vienna) 2013 Jan 27;120(1):49-54. Epub 2012 May 27.

Department of Physiology, Fujita Health University School of Medicine, Toyoake, Aichi, 470-1192, Japan.

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http://dx.doi.org/10.1007/s00702-012-0828-5DOI Listing
January 2013

Adipose tissue-derived mesenchymal stem cell transplantation promotes hepatic regeneration after hepatic ischemia-reperfusion and subsequent hepatectomy in rats.

J Surg Res 2012 Nov 28;178(1):63-70. Epub 2012 Mar 28.

Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S002248041200089
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http://dx.doi.org/10.1016/j.jss.2012.02.014DOI Listing
November 2012

Effects of aripiprazole and clozapine on the treatment of glycolytic carbon in PC12 cells.

J Neural Transm (Vienna) 2012 Nov 4;119(11):1327-42. Epub 2012 Mar 4.

Department of Physiology, Fujita Health University School of Medicine, Toyoake 470-1192, Japan.

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http://dx.doi.org/10.1007/s00702-012-0782-2DOI Listing
November 2012

Subventricular zone under the neuroinflammatory stress and Parkinson's disease.

Cell Mol Neurobiol 2012 Jul 22;32(5):777-85. Epub 2011 Dec 22.

Department of Physiology, Fujita Health University School of Medicine, Toyoake, Japan.

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http://dx.doi.org/10.1007/s10571-011-9783-1DOI Listing
July 2012

Poly(A) tail length of neurohypophysial hormones is shortened under endoplasmic reticulum stress.

Endocrinology 2011 Dec 4;152(12):4846-55. Epub 2011 Oct 4.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1210/en.2011-1415DOI Listing
December 2011

Personalized assessment of oxidative cellular damages associated with diabetes using erythrocytes adhesion assay.

J Biosci Bioeng 2011 Dec 6;112(6):635-7. Epub 2011 Sep 6.

Department of Biotechnology, School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan.

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http://dx.doi.org/10.1016/j.jbiosc.2011.08.003DOI Listing
December 2011

Repeated glucoprivation delayed hyperphagic responses while activating neuropeptide Y neurons in rats.

Peptides 2011 Apr 22;32(4):763-9. Epub 2010 Dec 22.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1016/j.peptides.2010.12.009DOI Listing
April 2011

Minocycline prevents osmotic demyelination syndrome by inhibiting the activation of microglia.

J Am Soc Nephrol 2010 Dec 28;21(12):2090-8. Epub 2010 Oct 28.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya, Japan.

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http://dx.doi.org/10.1681/ASN.2010040438DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014022PMC
December 2010

[Melanin-concentrating hormone].

Nihon Rinsho 2010 Jul;68 Suppl 7:230-3

Department of Metabolic Medicine, Nagoya University, Graduate School of Medicine.

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July 2010

Acute homeostatic responses to increased fat consumption in MCH1R knockout mice.

J Mol Neurosci 2010 Nov 22;42(3):459-63. Epub 2010 Apr 22.

Department of Pharmacology, University of California, 369 Med Surge II, Irvine, CA 92612, USA.

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http://dx.doi.org/10.1007/s12031-010-9358-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2955453PMC
November 2010

Activation of vasopressin neurons leads to phenotype progression in a mouse model for familial neurohypophysial diabetes insipidus.

Am J Physiol Regul Integr Comp Physiol 2010 Feb 2;298(2):R486-93. Epub 2009 Dec 2.

Department of Endocrinology and Diabetes, Field of Internal Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

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http://www.physiology.org/doi/10.1152/ajpregu.00529.2009
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http://dx.doi.org/10.1152/ajpregu.00529.2009DOI Listing
February 2010

Incomplete posture adjustment during rapid arm movement.

Percept Mot Skills 2009 Jun;108(3):915-32

Department of Physical Therapeutics, School of Nursing and Rehabilitation Sciences, Showa University, 1865 Toka-ichiba, Midori-ku, Yokohama, Kanagawa 226-8555, Japan.

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http://dx.doi.org/10.2466/PMS.108.3.915-932DOI Listing
June 2009

The medial hypothalamus is required for the feeding response to glucoprivation but not to food deprivation.

Neurosci Lett 2009 Oct 5;464(1):6-9. Epub 2009 Aug 5.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1016/j.neulet.2009.08.005DOI Listing
October 2009

The melanin-concentrating hormone system modulates cocaine reward.

Proc Natl Acad Sci U S A 2009 Apr 2;106(16):6772-7. Epub 2009 Apr 2.

Department of Pharmacology, University of California, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1073/pnas.0811331106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2672513PMC
April 2009

Progressive polyuria without vasopressin neuron loss in a mouse model for familial neurohypophysial diabetes insipidus.

Am J Physiol Regul Integr Comp Physiol 2009 May 18;296(5):R1641-9. Epub 2009 Mar 18.

Department of Endocrinology and Diabetes, Field of Internal Medicine, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1152/ajpregu.00034.2009DOI Listing
May 2009

Inflammatory cytokines regulate glycoprotein subunit beta5 of thyrostimulin through nuclear factor-kappaB.

Endocrinology 2009 May 18;150(5):2237-43. Epub 2008 Dec 18.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Aichi 466-8550, Japan.

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http://dx.doi.org/10.1210/en.2008-0823DOI Listing
May 2009

Interaction torque contributes to planar reaching at slow speed.

Biomed Eng Online 2008 Oct 22;7:27. Epub 2008 Oct 22.

Department of Physical Therapeutics, School of Nursing and Rehabilitation, Showa University, 1865 Toka-ichiba, Midori-ku, Yokohama, 226-8555, Japan.

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http://dx.doi.org/10.1186/1475-925X-7-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2577090PMC
October 2008

Direct and indirect modulation of neuropeptide Y gene expression in response to hypoglycemia in rat arcuate nucleus.

FEBS Lett 2008 Oct 1;582(25-26):3632-8. Epub 2008 Oct 1.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1016/j.febslet.2008.09.045DOI Listing
October 2008

Glucocorticoids increase neuropeptide Y and agouti-related peptide gene expression via adenosine monophosphate-activated protein kinase signaling in the arcuate nucleus of rats.

Endocrinology 2008 Sep 5;149(9):4544-53. Epub 2008 Jun 5.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1210/en.2008-0229DOI Listing
September 2008

The melanin-concentrating hormone system and its physiological functions.

Results Probl Cell Differ 2008 ;46:159-79

Graduate School of Integrated Arts and Sciences, Hiroshima University, Hiroshima, Japan.

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http://dx.doi.org/10.1007/400_2007_052DOI Listing
August 2008

Peripherally administered baclofen reduced food intake and body weight in db/db as well as diet-induced obese mice.

FEBS Lett 2007 Oct 17;581(25):4857-64. Epub 2007 Sep 17.

Department of Endocrinology and Diabetes, Field of Internal Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

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http://doi.wiley.com/10.1016/j.febslet.2007.09.011
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http://dx.doi.org/10.1016/j.febslet.2007.09.011DOI Listing
October 2007

Insulin is not a prerequisite for rapid regulation of neuropeptide Y gene transcription in the arcuate nucleus in food-restricted rats.

Neurosci Lett 2007 Jun 8;420(1):61-5. Epub 2007 Apr 8.

Department of Endocrinology and Diabetes, Field of Internal Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S030439400700422
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http://dx.doi.org/10.1016/j.neulet.2007.04.008DOI Listing
June 2007

The LIM domain homeobox gene isl-1 is a positive regulator of glycoprotein alpha 2 (GPA2), a subunit of thyrostimulin.

Regul Pept 2007 Jul 8;142(1-2):60-7. Epub 2007 Feb 8.

Department of Endocrinology and Diabetes, Nagoya University Graduate School of Medicine, Japan.

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http://dx.doi.org/10.1016/j.regpep.2007.01.009DOI Listing
July 2007

Central administration of melanocortin agonist increased insulin sensitivity in diet-induced obese rats.

FEBS Lett 2007 Mar 16;581(6):1131-6. Epub 2007 Feb 16.

Department of Endocrinology and Diabetes, Field of Internal Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

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http://doi.wiley.com/10.1016/j.febslet.2007.02.019
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http://dx.doi.org/10.1016/j.febslet.2007.02.019DOI Listing
March 2007

Differential expression of the thyrostimulin subunits, glycoprotein alpha2 and beta5 in the rat pituitary.

J Mol Endocrinol 2006 Aug;37(1):39-50

Department of Pharmacology, University of California-Irvine, Irvine, CA 92612, USA.

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http://dx.doi.org/10.1677/jme.1.01932DOI Listing
August 2006

Ghrelin increases neuropeptide Y and agouti-related peptide gene expression in the arcuate nucleus in rat hypothalamic organotypic cultures.

Endocrinology 2006 Nov 3;147(11):5102-9. Epub 2006 Aug 3.

Department of Endocrinology and Diabetes, Field of Internal Medicine, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2006-0104DOI Listing
November 2006

Ectopic expression of KNOTTED1-like homeobox protein induces expression of cytokinin biosynthesis genes in rice.

Plant Physiol 2006 Sep 21;142(1):54-62. Epub 2006 Jul 21.

Field Production Science Center, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Nishi-Tokyo, Tokyo 188-0002, Japan.

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http://www.plantphysiol.org/cgi/doi/10.1104/pp.106.085811
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http://dx.doi.org/10.1104/pp.106.085811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557621PMC
September 2006

Salusin beta is a surrogate ligand of the mas-like G protein-coupled receptor MrgA1.

Eur J Pharmacol 2006 Jun 5;539(3):145-50. Epub 2006 Apr 5.

Department of Pharmacology, University of California, Irvine, CA 92697, USA.

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http://dx.doi.org/10.1016/j.ejphar.2006.03.064DOI Listing
June 2006

Members of TALE and WUS subfamilies of homeodomain proteins with potentially important functions in development form dimers within each subfamily in rice.

Genes Genet Syst 2005 Aug;80(4):261-7

Graduate School of Bioagricultural Sciences, Nagoya University, Aichi, Japan.

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http://dx.doi.org/10.1266/ggs.80.261DOI Listing
August 2005

Insulin inhibits neuropeptide Y gene expression in the arcuate nucleus through GABAergic systems.

J Neurosci 2005 Sep;25(38):8657-64

Department of Endocrinology and Diabetes, Field of Internal Medicine, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.2739-05.2
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http://dx.doi.org/10.1523/JNEUROSCI.2739-05.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6725519PMC
September 2005

[Melanin-concentrating hormone (MCH)].

Nihon Rinsho 2005 Aug;63 Suppl 8:204-7

Department of Metabolic Diseases, Field of Internal Medicine, Nagoya University, Graduate School of Medicine.

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August 2005

Vasopressin gene transcription increases in response to decreases in plasma volume, but not to increases in plasma osmolality, in chronically dehydrated rats.

Am J Physiol Endocrinol Metab 2006 Feb 6;290(2):E213-7. Epub 2005 Sep 6.

Dept. of Endocrinology and Diabetes, Nagoya Univ. Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan.

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http://www.physiology.org/doi/10.1152/ajpendo.00158.2005
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http://dx.doi.org/10.1152/ajpendo.00158.2005DOI Listing
February 2006

Transgenic rat models of vasopressin overexpression.

Nagoya J Med Sci 2003 Nov;66(3-4):87-93

Department of Metabolic Diseases, Field of Internal Medicine, Nagoya University Graduate School of Medicine, Japan.

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November 2003

Altered cardiovascular regulation in arginine vasopressin-overexpressing transgenic rat.

Am J Physiol Endocrinol Metab 2003 Dec 12;285(6):E1161-6. Epub 2003 Aug 12.

Department of of Internal Medicine, Nagoya University Graduate School of Medicine, Nagoya 466-8550, Japan.

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http://dx.doi.org/10.1152/ajpendo.00570.2002DOI Listing
December 2003