Publications by authors named "Hiroshi Kawamoto"

100Publications

Discovery of ORN0829, a potent dual orexin 1/2 receptor antagonist for the treatment of insomnia.

Bioorg Med Chem 2020 07 11;28(13):115489. Epub 2020 Apr 11.

Discovery Research Laboratories, Taisho Pharmaceutical Co., Ltd., 1-403 Yoshino-cho, Kita-ku, Saitama 331-9530, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.bmc.2020.115489DOI Listing
July 2020

High Frequency Production of T Cell-Derived iPSC Clones Capable of Generating Potent Cytotoxic T Cells.

Mol Ther Methods Clin Dev 2020 Mar 24;16:126-135. Epub 2019 Dec 24.

Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto 606-8507, Japan.

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http://dx.doi.org/10.1016/j.omtm.2019.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965501PMC
March 2020

A Phase I/IIa Study of Antidisialoganglioside Antibody Dinutuximab in Japanese Patients With Neuroblastoma.

J Pediatr Hematol Oncol 2019 Dec 4. Epub 2019 Dec 4.

Department of Clinical Immuno Oncology, Clinical Research Institute of Clinical Pharmacology and Therapeutics, Showa University, Tokyo.

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http://dx.doi.org/10.1097/MPH.0000000000001684DOI Listing
December 2019

[Mass-Production of Tumor Antigen-Specific Cytotoxic T Lymphocytes Using the iPS Cell Technology-Development of "Off-the-Shelf T Cells"for the Use in Allogeneic Transfusion Settings].

Gan To Kagaku Ryoho 2019 Nov;46(11):1677-1682

Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University.

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November 2019

Using Human Induced Pluripotent Stem Cells for the Generation of Tumor Antigen-specific T Cells.

J Vis Exp 2019 10 24(152). Epub 2019 Oct 24.

Surgery Branch, National Cancer Institute, NIH; Center for Cell-Based Therapy, National Cancer Institute, NIH.

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http://dx.doi.org/10.3791/59997DOI Listing
October 2019

Identification of a genomic enhancer that enforces proper apoptosis induction in thymic negative selection.

Nat Commun 2019 06 13;10(1):2603. Epub 2019 Jun 13.

The Thomas N. Sato BioMEC-X Laboratories, Advanced Telecommunications Research Institute International (ATR), Soraku-gun, Kyoto, 619-0237, Japan.

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http://dx.doi.org/10.1038/s41467-019-10525-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6565714PMC
June 2019

Cloning and expansion of antigen-specific T cells using iPS cell technology: development of "off-the-shelf" T cells for the use in allogeneic transfusion settings.

Int J Hematol 2018 Mar 31;107(3):271-277. Epub 2018 Jan 31.

Laboratory of Immunology, Institute for Frontier Life and Medical Science, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan.

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http://dx.doi.org/10.1007/s12185-018-2399-1DOI Listing
March 2018

Cbfβ2 controls differentiation of and confers homing capacity to prethymic progenitors.

J Exp Med 2018 02 17;215(2):595-610. Epub 2018 Jan 17.

Laboratory for Transcriptional Regulation, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan

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http://dx.doi.org/10.1084/jem.20171221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789415PMC
February 2018

Impact of laparoscopic liver resection on bleeding complications in patients receiving antithrombotics.

World J Gastrointest Endosc 2017 Aug;9(8):396-404

Takahisa Fujikawa, Hiroshi Kawamoto, Yuichiro Kawamura, Norio Emoto, Yusuke Sakamoto, Akira Tanaka, Department of Surgery, Kokura Memorial Hospital, Fukuoka 802-8555, Japan.

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http://dx.doi.org/10.4253/wjge.v9.i8.396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5565505PMC
August 2017

NK Cell Alloreactivity against KIR-Ligand-Mismatched HLA-Haploidentical Tissue Derived from HLA Haplotype-Homozygous iPSCs.

Stem Cell Reports 2017 09 31;9(3):853-867. Epub 2017 Aug 31.

Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.07.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5599245PMC
September 2017

FANTOM5 CAGE profiles of human and mouse samples.

Authors:
Shuhei Noguchi Takahiro Arakawa Shiro Fukuda Masaaki Furuno Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Kaoru Kaida Ai Kaiho Mutsumi Kanamori-Katayama Tsugumi Kawashima Miki Kojima Atsutaka Kubosaki Ri-Ichiroh Manabe Mitsuyoshi Murata Sayaka Nagao-Sato Kenichi Nakazato Noriko Ninomiya Hiromi Nishiyori-Sueki Shohei Noma Eri Saijyo Akiko Saka Mizuho Sakai Christophe Simon Naoko Suzuki Michihira Tagami Shoko Watanabe Shigehiro Yoshida Peter Arner Richard A Axton Magda Babina J Kenneth Baillie Timothy C Barnett Anthony G Beckhouse Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher Ailsa J Carlisle Hans C Clevers Carrie A Davis Michael Detmar Taeko Dohi Albert S B Edge Matthias Edinger Anna Ehrlund Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Mary C Farach-Carson Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley M Forrester Rie Fujita Jun-Ichi Furusawa Teunis B Geijtenbeek Thomas Gingeras Daniel Goldowitz Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Yuki Hasegawa Meenhard Herlyn Peter Heutink Kelly J Hitchens David A Hume Tomokatsu Ikawa Yuri Ishizu Chieko Kai Hiroshi Kawamoto Yuki I Kawamura Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura Sarah Klein S Peter Klinken Alan J Knox Soichi Kojima Haruhiko Koseki Shigeo Koyasu Weonju Lee Andreas Lennartsson Alan Mackay-Sim Niklas Mejhert Yosuke Mizuno Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Kelly J Morris Hozumi Motohashi Christine L Mummery Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Tadasuke Nozaki Soichi Ogishima Naganari Ohkura Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Swati Pradhan-Bhatt Xian-Yang Qin Michael Rehli Patrizia Rizzu Sugata Roy Antti Sajantila Shimon Sakaguchi Hiroki Sato Hironori Satoh Suzana Savvi Alka Saxena Christian Schmidl Claudio Schneider Gundula G Schulze-Tanzil Anita Schwegmann Guojun Sheng Jay W Shin Daisuke Sugiyama Takaaki Sugiyama Kim M Summers Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Andru Tomoiu Hiroo Toyoda Marc van de Wetering Linda M van den Berg Roberto Verardo Dipti Vijayan Christine A Wells Louise N Winteringham Ernst Wolvetang Yoko Yamaguchi Masayuki Yamamoto Chiyo Yanagi-Mizuochi Misako Yoneda Yohei Yonekura Peter G Zhang Silvia Zucchelli Imad Abugessaisa Erik Arner Jayson Harshbarger Atsushi Kondo Timo Lassmann Marina Lizio Serkan Sahin Thierry Sengstag Jessica Severin Hisashi Shimoji Masanori Suzuki Harukazu Suzuki Jun Kawai Naoto Kondo Masayoshi Itoh Carsten O Daub Takeya Kasukawa Hideya Kawaji Piero Carninci Alistair R R Forrest Yoshihide Hayashizaki

Sci Data 2017 08 29;4:170112. Epub 2017 Aug 29.

RIKEN Omics Science Center, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1038/sdata.2017.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5574368PMC
August 2017

Phase I study of perifosine monotherapy in patients with recurrent or refractory neuroblastoma.

Pediatr Blood Cancer 2017 Nov 18;64(11). Epub 2017 May 18.

Department of Pediatrics, Kawagoe Preventive Medical Center Clinic, Saitama, Japan.

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http://dx.doi.org/10.1002/pbc.26623DOI Listing
November 2017

Design of high-quality compound library and open innovation.

Nihon Yakurigaku Zasshi 2017 ;149(4):180-185

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http://dx.doi.org/10.1254/fpj.149.180DOI Listing
July 2017

Successful resection of pancreatic head cancer in a patient with circumportal pancreas: a case report with technical consideration.

Innov Surg Sci 2017 Mar 28;2(1):33-37. Epub 2017 Feb 28.

Department of Surgery, Kokura Memorial Hospital, Fukuoka, Japan.

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http://dx.doi.org/10.1515/iss-2017-0003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754010PMC
March 2017

Is breast cancer surgery safely performed in patients receiving antithrombotic therapy?

Innov Surg Sci 2017 Mar 21;2(1):15-21. Epub 2017 Feb 21.

Department of Surgery, Kokura Memorial Hospital, Kitakyushu, Fukuoka, Japan.

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http://www.degruyter.com/view/j/iss.2017.2.issue-1/iss-2017-
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http://dx.doi.org/10.1515/iss-2017-0001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754011PMC
March 2017

Radiation absorbed dose estimates for 18F-BPA PET.

Acta Radiol 2017 Sep 19;58(9):1094-1100. Epub 2017 Jan 19.

4 Department of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1177/0284185116688378DOI Listing
September 2017

Regeneration of CD8αβ T Cells from T-cell-Derived iPSC Imparts Potent Tumor Antigen-Specific Cytotoxicity.

Cancer Res 2016 12 21;76(23):6839-6850. Epub 2016 Nov 21.

Laboratory of Immunology, Institute for Frontier Life and Medical Sciences, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-1149DOI Listing
December 2016

Regeneration of tumor antigen-specific CTLs utilizing iPS technology.

Rinsho Ketsueki 2016 08;57(8):1066-73

Department of Immunology, Institute for Frontier Medical Science, Kyoto University.

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http://dx.doi.org/10.11406/rinketsu.57.1066DOI Listing
August 2016

Transient Tcf3 Gene Repression by TALE-Transcription Factor Targeting.

Appl Biochem Biotechnol 2016 Dec 12;180(8):1559-1573. Epub 2016 Jul 12.

Division of Medical Bioengineering, Graduate School of Natural Science and Technology, Okayama University, Okayama, 700-8530, Japan.

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http://dx.doi.org/10.1007/s12010-016-2187-4DOI Listing
December 2016

CIC-rearranged Sarcomas: A Study of 20 Cases and Comparisons With Ewing Sarcomas.

Am J Surg Pathol 2016 Mar;40(3):313-23

Departments of *Pathology and Clinical Laboratories §Medical Oncology ∥Musculoskeletal Oncology ¶Pediatric Oncology #Head and Neck Oncology †Rare Cancer Center, National Cancer Center Hospital §§Department of Pathology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo Departments of ‡Diagnostic Pathology **Neurosurgery, Kainan Hospital, Aichi Departments of ††Orthopedic Surgery ‡‡Clinical Laboratory Medicine and Diagnostic Pathology, Shiga University of Medical Science, Shiga, Japan.

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http://dx.doi.org/10.1097/PAS.0000000000000570DOI Listing
March 2016

Induced Developmental Arrest of Early Hematopoietic Progenitors Leads to the Generation of Leukocyte Stem Cells.

Stem Cell Reports 2015 Nov;5(5):716-727

Laboratory for Lymphocyte Development, RIKEN Research Center for Allergy and Immunology, Yokohama 230-0045, Japan; Department of Immunology, Institute for Frontier Medical Sciences, Kyoto University, Kyoto 606-8507, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2015.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649263PMC
November 2015

Successful Treatment of Extra-Renal Noncerebral Rhabdoid Tumors with VIDE.

Pediatr Blood Cancer 2016 Feb 15;63(2):352-4. Epub 2015 Oct 15.

Division of Pediatric Oncology, National Cancer Center Hospital East.

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http://dx.doi.org/10.1002/pbc.25777DOI Listing
February 2016

CNOT3 contributes to early B cell development by controlling Igh rearrangement and p53 mRNA stability.

J Exp Med 2015 Aug 3;212(9):1465-79. Epub 2015 Aug 3.

Laboratory of Lymphocyte Differentiation, WPI Immunology Frontier Research Center, Osaka University, Suita, Osaka 565-0871, Japan Laboratory for Integrative Genomics, Laboratory for Developmental Genetics, Laboratory for Immune Regeneration, and Laboratory for Lymphocyte Differentiation, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, Kanagawa 230-0045, Japan

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http://dx.doi.org/10.1084/jem.20150384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548056PMC
August 2015

BTB-ZF Protein Znf131 Regulates Cell Growth of Developing and Mature T Cells.

J Immunol 2015 Aug 1;195(3):982-93. Epub 2015 Jul 1.

Laboratory of Self Defense Gene Regulation, Tokyo Metropolitan Institute of Medical Science, Tokyo 156-8506, Japan;

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http://dx.doi.org/10.4049/jimmunol.1500602DOI Listing
August 2015

Severe hypercalcemia following denosumab treatment in a juvenile patient.

J Bone Miner Metab 2016 Jan 9;34(1):118-22. Epub 2015 Jun 9.

Department of Orthopedic Surgery, Keio University, School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1007/s00774-015-0677-zDOI Listing
January 2016

[Case report of disseminated carcinomatosis of the bone marrow originating from gastric cancer with cancer-related disseminated intravascular coagulation successfully treated with recombinant human soluble thrombomodulin].

Gan To Kagaku Ryoho 2015 Mar;42(3):363-5

Dept. of Gastroenterological Surgery and Oncology, Tazuke Kofukai Foundation, Medical Research Institute, Kitano Hospital.

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March 2015

Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.

Authors:
Erik Arner Carsten O Daub Kristoffer Vitting-Seerup Robin Andersson Berit Lilje Finn Drabløs Andreas Lennartsson Michelle Rönnerblad Olga Hrydziuszko Morana Vitezic Tom C Freeman Ahmad M N Alhendi Peter Arner Richard Axton J Kenneth Baillie Anthony Beckhouse Beatrice Bodega James Briggs Frank Brombacher Margaret Davis Michael Detmar Anna Ehrlund Mitsuhiro Endoh Afsaneh Eslami Michela Fagiolini Lynsey Fairbairn Geoffrey J Faulkner Carmelo Ferrai Malcolm E Fisher Lesley Forrester Daniel Goldowitz Reto Guler Thomas Ha Mitsuko Hara Meenhard Herlyn Tomokatsu Ikawa Chieko Kai Hiroshi Kawamoto Levon M Khachigian S Peter Klinken Soichi Kojima Haruhiko Koseki Sarah Klein Niklas Mejhert Ken Miyaguchi Yosuke Mizuno Mitsuru Morimoto Kelly J Morris Christine Mummery Yutaka Nakachi Soichi Ogishima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry Ovchinnikov Robert Passier Margaret Patrikakis Ana Pombo Xian-Yang Qin Sugata Roy Hiroki Sato Suzana Savvi Alka Saxena Anita Schwegmann Daisuke Sugiyama Rolf Swoboda Hiroshi Tanaka Andru Tomoiu Louise N Winteringham Ernst Wolvetang Chiyo Yanagi-Mizuochi Misako Yoneda Susan Zabierowski Peter Zhang Imad Abugessaisa Nicolas Bertin Alexander D Diehl Shiro Fukuda Masaaki Furuno Jayson Harshbarger Akira Hasegawa Fumi Hori Sachi Ishikawa-Kato Yuri Ishizu Masayoshi Itoh Tsugumi Kawashima Miki Kojima Naoto Kondo Marina Lizio Terrence F Meehan Christopher J Mungall Mitsuyoshi Murata Hiromi Nishiyori-Sueki Serkan Sahin Sayaka Nagao-Sato Jessica Severin Michiel J L de Hoon Jun Kawai Takeya Kasukawa Timo Lassmann Harukazu Suzuki Hideya Kawaji Kim M Summers Christine Wells David A Hume Alistair R R Forrest Albin Sandelin Piero Carninci Yoshihide Hayashizaki

Science 2015 Feb 12;347(6225):1010-4. Epub 2015 Feb 12.

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http://dx.doi.org/10.1126/science.1259418DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681433PMC
February 2015

Clinicopathologic analysis of spindle cell/sclerosing rhabdomyosarcoma.

Pediatr Blood Cancer 2015 Jun 31;62(6):1011-6. Epub 2014 Dec 31.

Division of Pediatric Oncology, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1002/pbc.25367DOI Listing
June 2015

Clinical outcome of thymic lymphoepithelioma-like carcinoma: Case report of a 14-year-old male.

Oncol Lett 2014 Nov 22;8(5):2183-2186. Epub 2014 Aug 22.

Department of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious diseases Center, Komagome Hospital, Tokyo 113-8677, Japan.

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http://dx.doi.org/10.3892/ol.2014.2475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186619PMC
November 2014

Letter to the editor.

Radiat Prot Dosimetry 2015 Mar 16;163(4):533-4. Epub 2014 Sep 16.

Department of Diagnostic Radiology, National Cancer Centre Hospital, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104-0045, Japan.

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http://dx.doi.org/10.1093/rpd/ncu278DOI Listing
March 2015

TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells.

Nat Immunol 2014 Jul 18;15(7):646-656. Epub 2014 May 18.

Department of Microbiology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242.

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http://dx.doi.org/10.1038/ni.2897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064003PMC
July 2014

Differential SALL4 immunoexpression in malignant rhabdoid tumours and epithelioid sarcomas.

Histopathology 2015 Jan 28;66(2):252-61. Epub 2014 Oct 28.

Pathology and Clinical Laboratory, National Cancer Centre Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1111/his.12460DOI Listing
January 2015

A promoter-level mammalian expression atlas.

Authors:
Alistair R R Forrest Hideya Kawaji Michael Rehli J Kenneth Baillie Michiel J L de Hoon Vanja Haberle Timo Lassmann Ivan V Kulakovskiy Marina Lizio Masayoshi Itoh Robin Andersson Christopher J Mungall Terrence F Meehan Sebastian Schmeier Nicolas Bertin Mette Jørgensen Emmanuel Dimont Erik Arner Christian Schmidl Ulf Schaefer Yulia A Medvedeva Charles Plessy Morana Vitezic Jessica Severin Colin A Semple Yuri Ishizu Robert S Young Margherita Francescatto Intikhab Alam Davide Albanese Gabriel M Altschuler Takahiro Arakawa John A C Archer Peter Arner Magda Babina Sarah Rennie Piotr J Balwierz Anthony G Beckhouse Swati Pradhan-Bhatt Judith A Blake Antje Blumenthal Beatrice Bodega Alessandro Bonetti James Briggs Frank Brombacher A Maxwell Burroughs Andrea Califano Carlo V Cannistraci Daniel Carbajo Yun Chen Marco Chierici Yari Ciani Hans C Clevers Emiliano Dalla Carrie A Davis Michael Detmar Alexander D Diehl Taeko Dohi Finn Drabløs Albert S B Edge Matthias Edinger Karl Ekwall Mitsuhiro Endoh Hideki Enomoto Michela Fagiolini Lynsey Fairbairn Hai Fang Mary C Farach-Carson Geoffrey J Faulkner Alexander V Favorov Malcolm E Fisher Martin C Frith Rie Fujita Shiro Fukuda Cesare Furlanello Masaaki Furino Jun-ichi Furusawa Teunis B Geijtenbeek Andrew P Gibson Thomas Gingeras Daniel Goldowitz Julian Gough Sven Guhl Reto Guler Stefano Gustincich Thomas J Ha Masahide Hamaguchi Mitsuko Hara Matthias Harbers Jayson Harshbarger Akira Hasegawa Yuki Hasegawa Takehiro Hashimoto Meenhard Herlyn Kelly J Hitchens Shannan J Ho Sui Oliver M Hofmann Ilka Hoof Furni Hori Lukasz Huminiecki Kei Iida Tomokatsu Ikawa Boris R Jankovic Hui Jia Anagha Joshi Giuseppe Jurman Bogumil Kaczkowski Chieko Kai Kaoru Kaida Ai Kaiho Kazuhiro Kajiyama Mutsumi Kanamori-Katayama Artem S Kasianov Takeya Kasukawa Shintaro Katayama Sachi Kato Shuji Kawaguchi Hiroshi Kawamoto Yuki I Kawamura Tsugumi Kawashima Judith S Kempfle Tony J Kenna Juha Kere Levon M Khachigian Toshio Kitamura S Peter Klinken Alan J Knox Miki Kojima Soichi Kojima Naoto Kondo Haruhiko Koseki Shigeo Koyasu Sarah Krampitz Atsutaka Kubosaki Andrew T Kwon Jeroen F J Laros Weonju Lee Andreas Lennartsson Kang Li Berit Lilje Leonard Lipovich Alan Mackay-Sim Ri-ichiroh Manabe Jessica C Mar Benoit Marchand Anthony Mathelier Niklas Mejhert Alison Meynert Yosuke Mizuno David A de Lima Morais Hiromasa Morikawa Mitsuru Morimoto Kazuyo Moro Efthymios Motakis Hozumi Motohashi Christine L Mummery Mitsuyoshi Murata Sayaka Nagao-Sato Yutaka Nakachi Fumio Nakahara Toshiyuki Nakamura Yukio Nakamura Kenichi Nakazato Erik van Nimwegen Noriko Ninomiya Hiromi Nishiyori Shohei Noma Shohei Noma Tadasuke Noazaki Soichi Ogishima Naganari Ohkura Hiroko Ohimiya Hiroshi Ohno Mitsuhiro Ohshima Mariko Okada-Hatakeyama Yasushi Okazaki Valerio Orlando Dmitry A Ovchinnikov Arnab Pain Robert Passier Margaret Patrikakis Helena Persson Silvano Piazza James G D Prendergast Owen J L Rackham Jordan A Ramilowski Mamoon Rashid Timothy Ravasi Patrizia Rizzu Marco Roncador Sugata Roy Morten B Rye Eri Saijyo Antti Sajantila Akiko Saka Shimon Sakaguchi Mizuho Sakai Hiroki Sato Suzana Savvi Alka Saxena Claudio Schneider Erik A Schultes Gundula G Schulze-Tanzil Anita Schwegmann Thierry Sengstag Guojun Sheng Hisashi Shimoji Yishai Shimoni Jay W Shin Christophe Simon Daisuke Sugiyama Takaai Sugiyama Masanori Suzuki Naoko Suzuki Rolf K Swoboda Peter A C 't Hoen Michihira Tagami Naoko Takahashi Jun Takai Hiroshi Tanaka Hideki Tatsukawa Zuotian Tatum Mark Thompson Hiroo Toyodo Tetsuro Toyoda Elvind Valen Marc van de Wetering Linda M van den Berg Roberto Verado Dipti Vijayan Ilya E Vorontsov Wyeth W Wasserman Shoko Watanabe Christine A Wells Louise N Winteringham Ernst Wolvetang Emily J Wood Yoko Yamaguchi Masayuki Yamamoto Misako Yoneda Yohei Yonekura Shigehiro Yoshida Susan E Zabierowski Peter G Zhang Xiaobei Zhao Silvia Zucchelli Kim M Summers Harukazu Suzuki Carsten O Daub Jun Kawai Peter Heutink Winston Hide Tom C Freeman Boris Lenhard Vladimir B Bajic Martin S Taylor Vsevolod J Makeev Albin Sandelin David A Hume Piero Carninci Yoshihide Hayashizaki

Nature 2014 Mar;507(7493):462-70

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http://dx.doi.org/10.1038/nature13182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529748PMC
March 2014

Obturator hernia.

Intern Med 2013 ;52(11):1269

Digestive Disease Center, The Tazuke Kofukai Medical Research Institute, Kitano Hospital, Japan.

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http://dx.doi.org/10.2169/internalmedicine.52.0307DOI Listing
February 2014

Individual hematopoietic stem cells in human bone marrow of patients with aplastic anemia or myelodysplastic syndrome stably give rise to limited cell lineages.

Stem Cells 2013 Mar;31(3):536-46

Clinical Laboratory Science, Division of Health Sciences, Kanazawa University Graduate School of Medical Science, Kanazawa, Ishikawa, Japan.

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http://dx.doi.org/10.1002/stem.1301DOI Listing
March 2013

Regeneration of human tumor antigen-specific T cells from iPSCs derived from mature CD8(+) T cells.

Cell Stem Cell 2013 Jan;12(1):31-6

Laboratory for Developmental Genetics, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan.

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http://dx.doi.org/10.1016/j.stem.2012.12.006DOI Listing
January 2013

Thoracoamniotic shunting for fetal pleural effusions using a double-basket shunt.

Prenat Diagn 2012 Dec 8;32(13):1282-7. Epub 2012 Nov 8.

Department of Fetal-Maternal Medicine, Nagara Medical Center, Gifu, Japan.

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http://dx.doi.org/10.1002/pd.3994DOI Listing
December 2012

Process for immune defect and chromosomal translocation during early thymocyte development lacking ATM.

Blood 2012 Jul 18;120(4):789-99. Epub 2012 Jun 18.

Department of Pediatrics and Developmental Biology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1182/blood-2012-02-413195DOI Listing
July 2012

Runx1-Cbfβ facilitates early B lymphocyte development by regulating expression of Ebf1.

J Exp Med 2012 Jul 4;209(7):1255-62. Epub 2012 Jun 4.

Laboratory for Transcriptional Regulation, RIKEN Research Center for Allergy and Immunology, Tsurumi-ku, Yokohama 230-0045, Japan.

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http://dx.doi.org/10.1084/jem.20112745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3405506PMC
July 2012

Ultrasound prognostic factors after laser surgery for twin-twin transfusion syndrome to predict survival at 6 months.

Prenat Diagn 2011 Nov 8;31(11):1097-100. Epub 2011 Sep 8.

Division of Perinatology, Maternal and Perinatal Care Center, Seirei Hamamatsu General Hospital, Hamamatsu, Japan.

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http://dx.doi.org/10.1002/pd.2845DOI Listing
November 2011

Polycomb group gene Bmi1 plays a role in the growth of thymic epithelial cells.

Eur J Immunol 2011 Apr 14;41(4):1098-107. Epub 2011 Mar 14.

Department of Immunology, Graduate School of Biosciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, Japan.

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http://dx.doi.org/10.1002/eji.201040794DOI Listing
April 2011

The outcome and prognostic factors of twin-twin transfusion syndrome following fetoscopic laser surgery.

Prenat Diagn 2010 Dec;30(12-13):1185-91

Department of Maternal-Fetal and Neonatal Medicine, National Center for Child Health and Development, Tokyo, Japan.

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http://dx.doi.org/10.1002/pd.2647DOI Listing
December 2010

The role of the basic helix-loop-helix transcription factor Dec1 in the regulatory T cells.

J Immunol 2010 Dec 5;185(12):7330-9. Epub 2010 Nov 5.

Department of Developmental Biology, Research Institute for Radiation Biology and Medicine, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1001381
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December 2010

A map for lineage restriction of progenitors during hematopoiesis: the essence of the myeloid-based model.

Immunol Rev 2010 Nov;238(1):23-36

Laboratory for Lymphocyte Development, RIKEN Research Center for Allergy and Immunology, Yokohama, Japan.

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http://dx.doi.org/10.1111/j.1600-065X.2010.00959.xDOI Listing
November 2010

An essential developmental checkpoint for production of the T cell lineage.

Science 2010 Jul;329(5987):93-6

Laboratory for Lymphocyte Development, RIKEN Research Center for Allergy and Immunology, Yokohama 230-0045, Japan.

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http://dx.doi.org/10.1126/science.1188995DOI Listing
July 2010

Biphasic Aire expression in early embryos and in medullary thymic epithelial cells before end-stage terminal differentiation.

J Exp Med 2010 May 19;207(5):963-71. Epub 2010 Apr 19.

Division of Molecular Immunology, Institute for Enzyme Research, University of Tokushima, Tokushima 770-8503, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867289PMC
May 2010

Pharmacological effects of metabotropic glutamate receptor ligands on prepulse inhibition in DBA/2J mice.

Eur J Pharmacol 2010 Aug 2;639(1-3):99-105. Epub 2010 Apr 2.

Tsukuba Research Institute, Banyu Pharmaceutical Co., Ltd., 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan.

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August 2010

Poised lineage specification in multipotential hematopoietic stem and progenitor cells by the polycomb protein Bmi1.

Cell Stem Cell 2010 Mar;6(3):279-86

Department of Cellular and Molecular Medicine, Graduate School of Medicine, Chiba University, Chiba 260-8670, Japan.

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March 2010

Development of a beta-lactamase reporter gene assay for metabotropic glutamate receptor 1 by using coexpression of glutamate transporter.

J Biomol Screen 2010 Feb 19;15(2):148-58. Epub 2010 Jan 19.

Tsukuba Research Institute, Banyu Pharmaceutical Co., Ltd., Tsukuba, Ibaraki, Japan.

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February 2010

A revised scheme for developmental pathways of hematopoietic cells: the myeloid-based model.

Int Immunol 2010 Feb 6;22(2):65-70. Epub 2010 Jan 6.

Laboratory for Lymphocyte Development, RIKEN Research Center for Allergy and Immunology, Tsurumi-ku, Yokohama 230-0045, Japan.

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February 2010

Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells.

Nature 2010 Jan 20;463(7280):540-4. Epub 2009 Dec 20.

Department of Microbiology and Immunology, Keio University School of Medicine, Shinjuku-ku, Tokyo 160-8582, Japan.

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http://dx.doi.org/10.1038/nature08636DOI Listing
January 2010

Thymic cysts originate from Foxn1 positive thymic medullary epithelium.

Mol Immunol 2010 Feb 27;47(5):1106-13. Epub 2009 Nov 27.

Laboratory for Lymphocyte Development, RIKEN Research Centre for Allergy and Immunology, Yokohama, Japan.

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http://dx.doi.org/10.1016/j.molimm.2009.10.034DOI Listing
February 2010

Ectopically expressed PIR-B on T cells constitutively binds to MHC class I and attenuates T helper type 1 responses.

Int Immunol 2009 Oct 14;21(10):1151-61. Epub 2009 Aug 14.

Department of Experimental Immunology, Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan.

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October 2009

Synthesis and evaluation of a series of 2,4-diaminopyridine derivatives as potential positron emission tomography tracers for neuropeptide Y Y1 receptors.

Bioorg Med Chem Lett 2009 Sep 10;19(17):5124-7. Epub 2009 Jul 10.

Department of Medicinal Chemistry, Tsukuba Research Institute, Merck Research Laboratories, Banyu Pharmaceutical Co. Ltd, Okubo 3, Tsukuba, Ibaraki, Japan.

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September 2009

Optimization of a series of 2,4-diaminopyridines as neuropeptide Y Y1 receptor antagonists with reduced hERG activity.

Bioorg Med Chem Lett 2009 Aug 24;19(15):4325-9. Epub 2009 May 24.

Department of Medicinal Chemistry, Tsukuba Research Institute, Merck Research Laboratories, Banyu Pharmaceutical Co., Ltd, Okubo 3, Tsukuba, Ibaraki 300-2611, Japan.

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August 2009