Hiroshi Kajio

Hiroshi Kajio

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Hiroshi Kajio

Publications by authors named "Hiroshi Kajio"

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No beneficial effects of aspirin on secondary cardiovascular prevention in patients with type 2 diabetes using non-steroidal anti-inflammatory drugs.

Diabetes Obes Metab 2019 Aug 24;21(8):1978-1984. Epub 2019 Apr 24.

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/dom.13737DOI Listing
August 2019

Use of Nitrates and Risk of Cardiovascular Events in Patients With Heart Failure With Preserved Ejection Fraction.

Mayo Clin Proc 2019 Jul;94(7):1210-1220

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.mayocp.2018.11.032DOI Listing
July 2019

Contribution of pancreatic α-cell function to insulin sensitivity and glycemic variability in patients with type 1 diabetes.

J Diabetes Investig 2019 May 30;10(3):690-698. Epub 2018 Oct 30.

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://doi.wiley.com/10.1111/jdi.12949
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http://dx.doi.org/10.1111/jdi.12949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497601PMC
May 2019

Strategies for glycemic control in nonobese and obese type 2 diabetic patients with coronary artery disease.

Int J Cardiol 2019 05 7;282:1-6. Epub 2019 Feb 7.

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2019.02.008DOI Listing
May 2019

Optimal cardiac strategy based on the history of myocardial infarction in type 2 diabetic patients with coronary artery disease.

Sci Rep 2019 Mar 5;9(1):3502. Epub 2019 Mar 5.

Department of Diabetes, Endocrinology, and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1038/s41598-019-39857-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400970PMC
March 2019

Intensive Blood Pressure Treatment for Resistant Hypertension.

Hypertension 2019 Feb;73(2):415-423

From the Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343947PMC
February 2019

Urinary afamin levels are associated with the progression of diabetic nephropathy.

Diabetes Res Clin Pract 2019 Jan 6;147:37-46. Epub 2018 Mar 6.

Department of Diabetic Complications, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2018.02.034DOI Listing
January 2019

Thrombotic/Thrombolytic Balance as a Cardiac Treatment Determinant in Patients With Diabetes Mellitus and Coronary Artery Disease.

J Am Heart Assoc 2019 Jan;8(2):e011207

1 Department of Diabetes, Endocrinology, and Metabolism Center Hospital National Center for Global Health and Medicine Tokyo Japan.

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https://www.ahajournals.org/doi/10.1161/JAHA.118.011207
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http://dx.doi.org/10.1161/JAHA.118.011207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497335PMC
January 2019

Pulse pressure for selecting the optimal cardiac strategy in patients with type 2 diabetes and coronary artery disease.

Int J Cardiol 2018 Dec 2;273:1-7. Epub 2018 Aug 2.

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2018.07.143DOI Listing
December 2018

Durability of Glucose-Lowering Effect of the First Administration of Dulaglutide: A Retrospective, Single-Center, Single-Arm Study.

Diabetes Ther 2018 Oct 28;9(5):2127-2132. Epub 2018 Jul 28.

Department of Diabetes, Endocrinology and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1007/s13300-018-0474-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167306PMC
October 2018

Efficacy of renin-angiotensin system inhibitors for patients with heart failure with preserved ejection fraction and mild to moderate chronic kidney disease.

Eur J Prev Cardiol 2018 Aug 29;25(12):1268-1277. Epub 2018 May 29.

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1177/2047487318780035DOI Listing
August 2018

Benefits of Intensive Blood Pressure Treatment in Patients With Type 2 Diabetes Mellitus Receiving Standard but Not Intensive Glycemic Control.

Hypertension 2018 08 2;72(2):323-330. Epub 2018 Jul 2.

From the Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11408DOI Listing
August 2018

Low diastolic blood pressure and adverse outcomes in heart failure with preserved ejection fraction.

Int J Cardiol 2018 07 9;263:69-74. Epub 2018 Apr 9.

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2018.04.031DOI Listing
July 2018

Beta-blocker use and cardiovascular event risk in patients with heart failure with preserved ejection fraction.

Sci Rep 2018 Jun 22;8(1):9556. Epub 2018 Jun 22.

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1038/s41598-018-27799-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015007PMC
June 2018

Short-term changes in pancreatic α-cell function after the onset of fulminant type 1 diabetes.

J Diabetes Investig 2018 May 3;9(3):636-637. Epub 2018 May 3.

Department of Diabetes, Endocrinology, and Metabolism Center Hospital National Center for Global Health and Medicine Tokyo Japan.

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http://dx.doi.org/10.1111/jdi.12706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934243PMC
May 2018

Risk of All-Cause Mortality in Diabetic Patients Taking β-Blockers.

Mayo Clin Proc 2018 04 12;93(4):409-418. Epub 2018 Mar 12.

Diabetes and Metabolism Information Center, Research Institute, National Center for Global Health and Medicine, Tokyo National Center for Global Health and Medicine, Tokyo, Japan; Department of Public Health/Health Policy, the Universitiy of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.mayocp.2017.11.019DOI Listing
April 2018

Favorable effects of statins in the treatment of heart failure with preserved ejection fraction in patients without ischemic heart disease.

Int J Cardiol 2018 Mar 4;255:111-117. Epub 2018 Jan 4.

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.12.109DOI Listing
March 2018

High risk of renal dysfunction in patients with fulminant type 1 diabetes.

J Diabetes Investig 2018 Jan 13;9(1):146-151. Epub 2017 Apr 13.

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/jdi.12652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5754524PMC
January 2018

Favourable changes in mortality in people with diabetes: US NHANES 1999-2010.

Diabetes Obes Metab 2018 01 27;20(1):85-93. Epub 2017 Jul 27.

Department of Clinical Study and Informatics, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/dom.13039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724499PMC
January 2018

Statin Therapy in Patients With Low Serum Levels of Low-Density Lipoprotein Cholesterol.

Am J Cardiol 2017 Dec 30;120(11):1947-1954. Epub 2017 Aug 30.

Diabetes and Metabolism Information Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan; Department of Public Health/Health Policy, The University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.amjcard.2017.08.011DOI Listing
December 2017

Abdominal Obesity Is Associated With an Increased Risk of All-Cause Mortality in Patients With HFpEF.

J Am Coll Cardiol 2017 Dec;70(22):2739-2749

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jacc.2017.09.1111DOI Listing
December 2017

Design of and rationale for the Japan Diabetes compREhensive database project based on an Advanced electronic Medical record System (J-DREAMS).

Diabetol Int 2017 Nov 27;8(4):375-382. Epub 2017 Jun 27.

4Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655 Japan.

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http://dx.doi.org/10.1007/s13340-017-0326-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224921PMC
November 2017

Slowly Growing Adrenal Mass: A 20-Year Incubation.

Am J Med 2017 11 26;130(11):e479-e483. Epub 2017 Jul 26.

Department of Diabetes, Endocrinology, and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S00029343173077
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http://dx.doi.org/10.1016/j.amjmed.2017.07.008DOI Listing
November 2017

Insulinoma Presenting with Reactive Hypoglycemia: Evaluating the Effect of Tumor Resection via Continuous Glucose Monitoring.

Intern Med 2017 Nov 25;56(22):3067-3071. Epub 2017 Sep 25.

Department of Diabetes, Endocrinology and Metabolism, Center Hospital, National Center for Global Health and Medicine, Japan.

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http://dx.doi.org/10.2169/internalmedicine.8766-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725862PMC
November 2017

Association Between Caffeine Intake and All-Cause and Cause-Specific Mortality: A Population-Based Prospective Cohort Study.

Mayo Clin Proc 2017 08 8;92(8):1190-1202. Epub 2017 Jul 8.

Department of Clinical Study and Informatics, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan; Department of Public Health/Health Policy, the University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.mayocp.2017.03.010DOI Listing
August 2017

Association between hyperinsulinemia and increased risk of cancer death in nonobese and obese people: A population-based observational study.

Int J Cancer 2017 07 22;141(1):102-111. Epub 2017 Apr 22.

Diabetes and Metabolism Information Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1002/ijc.30729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5435954PMC
July 2017

Risk of Cardiovascular Events in Patients With Diabetes Mellitus on β-Blockers.

Hypertension 2017 07 30;70(1):103-110. Epub 2017 May 30.

From the Department of Diabetes, Endocrinology, and Metabolism, Center Hospital (T.T., H.K.), and Department of Clinical Study and Informatics, Center for Clinical Sciences (T.S.), National Center for Global Health and Medicine, Tokyo, Japan; Department of Public Health/Health Policy, the University of Tokyo, Japan (T.S.); Division of General Internal Medicine & Health Services Research, David Geffen School of Medicine at UCLA (M.F.S.); Department of Health Policy and Management, UCLA Fielding School of Public Health (M.F.S.); and Department of Endocrinology and Diabetes, Saitama Medical University, Japan (M.N.).

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.117.09259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739105PMC
July 2017

Effects of β-blockers on all-cause mortality in patients with type 2 diabetes and coronary heart disease.

Diabetes Obes Metab 2017 06 17;19(6):800-808. Epub 2017 Feb 17.

Department of Diabetes, Endocrinology and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/dom.12878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484336PMC
June 2017

A positive family history of hypertension might be associated with an accelerated onset of type 2 diabetes: Results from the National Center Diabetes Database (NCDD-02).

Endocr J 2017 May 18;64(5):515-520. Epub 2017 Mar 18.

Department of Diabetes Research and Diabetes and Metabolism Information Center, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ16-0521DOI Listing
May 2017

Accelerated decline of renal function in type 2 diabetes following severe hypoglycemia.

J Diabetes Complications 2016 May-Jun;30(4):681-5. Epub 2016 Jan 22.

Department of Diabetes Research, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo, Japan; Department of Endocrinology and Diabetes, Saitama Medical University, Saitama, Japan.

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http://dx.doi.org/10.1016/j.jdiacomp.2016.01.015DOI Listing
January 2017

Reduced serum level of leukocyte cell-derived chemotaxin 2 is associated with the presence of diabetic retinopathy.

Clin Chim Acta 2016 Dec 29;463:145-149. Epub 2016 Oct 29.

Department of Diabetic Complications, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Tokyo 162-8655, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2016.10.031DOI Listing
December 2016

Risks for Cardiovascular and Cardiac Deaths in Nonobese Patients With Diabetes and Coronary Heart Disease.

Mayo Clin Proc 2016 Nov 8;91(11):1545-1554. Epub 2016 Oct 8.

Department of Clinical Study and Informatics, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan; Department of Public Health/Health Policy, the University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.mayocp.2016.08.018DOI Listing
November 2016

Body mass index and the risk of cancer incidence in patients with type 2 diabetes in Japan: Results from the National Center Diabetes Database.

J Diabetes Investig 2016 Nov 5;7(6):908-914. Epub 2016 May 5.

Research Institute, Department of Diabetes Research and Diabetes and Metabolism Information Center, Diabetes Research Center, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/jdi.12522DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5089955PMC
November 2016

Sweet taste disorder and vascular complications in patients with abnormal glucose tolerance.

Int J Cardiol 2016 Oct 5;221:637-41. Epub 2016 Jul 5.

Department of Clinical Study and Informatics, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan; Department of Public Health/Health Policy, the University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2016.07.062DOI Listing
October 2016

Intensive Glycemic Therapy in Patients With Type 2 Diabetes on β-Blockers.

Diabetes Care 2016 Oct 26;39(10):1818-26. Epub 2016 Jul 26.

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.2337/dc16-0721DOI Listing
October 2016

Improvement of glycemic control without severe hypoglycemia in a type 1 diabetes patient undergoing hemodialysis after a change from insulin glargine to insulin degludec.

J Diabetes Investig 2016 Sep;7(5):805-6

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/jdi.12500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009146PMC
September 2016

Beneficial effects through aggressive coronary screening for type 2 diabetes patients with advanced vascular complications.

Medicine (Baltimore) 2016 Aug;95(33):e4307

aDepartment of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo bDivision of General Medicine, Jichi Medical University Graduate School of Medicine, Shimotsuke cDepartment of Clinical Study and Informatics, Center for Clinical Sciences, National Center for Global Health and Medicine dDepartment of Public Health/Health Policy, the University of Tokyo eDepartment of Diabetes Research, Diabetes Research Center fDepartment of Nuclear Medicine gDepartment of Cardiovascular Medicine, Center Hospital, National Center for Global Health and Medicine, Tokyo hFirst Department of Comprehensive Medicine, Saitama Medical Center, Jichi Medical University School of Medicine iDepartment of Endocrinology and Diabetes, Saitama Medical University, Saitama, Japan.

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http://dx.doi.org/10.1097/MD.0000000000004307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370783PMC
August 2016

Obesity, diabetes, and length of time in the United States: Analysis of National Health and Nutrition Examination Survey 1999 to 2012.

Medicine (Baltimore) 2016 Aug;95(35):e4578

aDepartment of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo, Japan bDepartment of Clinical Study and Informatics, Center for Clinical Sciences, National Center for Global Health and Medicine, Tokyo, Japan cDepartment of Public Health/Health Policy, the University of Tokyo, Tokyo, Japan.

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http://dx.doi.org/10.1097/MD.0000000000004578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5008551PMC
August 2016

Acute Multiple Arteriovenous Thromboses in a Patient with Diabetic Ketoacidosis.

Intern Med 2015 15;54(16):2025-8. Epub 2015 Aug 15.

Department of Diabetes, Endocrinology, and Metabolism, National Center for Global Health and Medicine, Japan.

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https://www.jstage.jst.go.jp/article/internalmedicine/54/16/
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http://dx.doi.org/10.2169/internalmedicine.54.4087DOI Listing
April 2016

Constipation, hard stools, fecal urgency, and incomplete evacuation, but not diarrhea is associated with diabetes and its related factors.

World J Gastroenterol 2016 Mar;22(11):3252-60

Noriko Ihana-Sugiyama, Ritsuko Yamamoto-Honda, Hiroshi Kajio, Mitsuhiko Noda, Department of Diabetes, Endocrinology and Metabolism, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.

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http://dx.doi.org/10.3748/wjg.v22.i11.3252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4790001PMC
March 2016

Possible discrepancy of HbA1c values and its assessment among patients with chronic renal failure, hemodialysis and other diseases.

Clin Exp Nephrol 2015 Dec 1;19(6):1179-83. Epub 2015 Apr 1.

Department of Diabetes Research, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655, Japan.

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http://dx.doi.org/10.1007/s10157-015-1110-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679780PMC
December 2015

Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.

Authors:
Norihiro Kato Marie Loh Fumihiko Takeuchi Niek Verweij Xu Wang Weihua Zhang Tanika N Kelly Danish Saleheen Benjamin Lehne Irene Mateo Leach Alexander W Drong James Abbott Simone Wahl Sian-Tsung Tan William R Scott Gianluca Campanella Marc Chadeau-Hyam Uzma Afzal Tarunveer S Ahluwalia Marc Jan Bonder Peng Chen Abbas Dehghan Todd L Edwards Tõnu Esko Min Jin Go Sarah E Harris Jaana Hartiala Silva Kasela Anuradhani Kasturiratne Chiea-Chuen Khor Marcus E Kleber Huaixing Li Zuan Yu Mok Masahiro Nakatochi Nur Sabrina Sapari Richa Saxena Alexandre F R Stewart Lisette Stolk Yasuharu Tabara Ai Ling Teh Ying Wu Jer-Yuarn Wu Yi Zhang Imke Aits Alexessander Da Silva Couto Alves Shikta Das Rajkumar Dorajoo Jemma C Hopewell Yun Kyoung Kim Robert W Koivula Jian'an Luan Leo-Pekka Lyytikäinen Quang N Nguyen Mark A Pereira Iris Postmus Olli T Raitakari Molly Scannell Bryan Robert A Scott Rossella Sorice Vinicius Tragante Michela Traglia Jon White Ken Yamamoto Yonghong Zhang Linda S Adair Alauddin Ahmed Koichi Akiyama Rasheed Asif Tin Aung Inês Barroso Andrew Bjonnes Timothy R Braun Hui Cai Li-Ching Chang Chien-Hsiun Chen Ching-Yu Cheng Yap-Seng Chong Rory Collins Regina Courtney Gail Davies Graciela Delgado Loi D Do Pieter A Doevendans Ron T Gansevoort Yu-Tang Gao Tanja B Grammer Niels Grarup Jagvir Grewal Dongfeng Gu Gurpreet S Wander Anna-Liisa Hartikainen Stanley L Hazen Jing He Chew-Kiat Heng James E Hixson Albert Hofman Chris Hsu Wei Huang Lise L N Husemoen Joo-Yeon Hwang Sahoko Ichihara Michiya Igase Masato Isono Johanne M Justesen Tomohiro Katsuya Muhammad G Kibriya Young Jin Kim Miyako Kishimoto Woon-Puay Koh Katsuhiko Kohara Meena Kumari Kenneth Kwek Nanette R Lee Jeannette Lee Jiemin Liao Wolfgang Lieb David C M Liewald Tatsuaki Matsubara Yumi Matsushita Thomas Meitinger Evelin Mihailov Lili Milani Rebecca Mills Nina Mononen Martina Müller-Nurasyid Toru Nabika Eitaro Nakashima Hong Kiat Ng Kjell Nikus Teresa Nutile Takayoshi Ohkubo Keizo Ohnaka Sarah Parish Lavinia Paternoster Hao Peng Annette Peters Son T Pham Mohitha J Pinidiyapathirage Mahfuzar Rahman Hiromi Rakugi Olov Rolandsson Michelle Ann Rozario Daniela Ruggiero Cinzia F Sala Ralhan Sarju Kazuro Shimokawa Harold Snieder Thomas Sparsø Wilko Spiering John M Starr David J Stott Daniel O Stram Takao Sugiyama Silke Szymczak W H Wilson Tang Lin Tong Stella Trompet Väinö Turjanmaa Hirotsugu Ueshima André G Uitterlinden Satoshi Umemura Marja Vaarasmaki Rob M van Dam Wiek H van Gilst Dirk J van Veldhuisen Jorma S Viikari Melanie Waldenberger Yiqin Wang Aili Wang Rory Wilson Tien-Yin Wong Yong-Bing Xiang Shuhei Yamaguchi Xingwang Ye Robin D Young Terri L Young Jian-Min Yuan Xueya Zhou Folkert W Asselbergs Marina Ciullo Robert Clarke Panos Deloukas Andre Franke Paul W Franks Steve Franks Yechiel Friedlander Myron D Gross Zhirong Guo Torben Hansen Marjo-Riitta Jarvelin Torben Jørgensen J Wouter Jukema Mika Kähönen Hiroshi Kajio Mika Kivimaki Jong-Young Lee Terho Lehtimäki Allan Linneberg Tetsuro Miki Oluf Pedersen Nilesh J Samani Thorkild I A Sørensen Ryoichi Takayanagi Daniela Toniolo Habibul Ahsan Hooman Allayee Yuan-Tsong Chen John Danesh Ian J Deary Oscar H Franco Lude Franke Bastiaan T Heijman Joanna D Holbrook Aaron Isaacs Bong-Jo Kim Xu Lin Jianjun Liu Winfried März Andres Metspalu Karen L Mohlke Dharambir K Sanghera Xiao-Ou Shu Joyce B J van Meurs Eranga Vithana Ananda R Wickremasinghe Cisca Wijmenga Bruce H W Wolffenbuttel Mitsuhiro Yokota Wei Zheng Dingliang Zhu Paolo Vineis Soterios A Kyrtopoulos Jos C S Kleinjans Mark I McCarthy Richie Soong Christian Gieger James Scott Yik-Ying Teo Jiang He Paul Elliott E Shyong Tai Pim van der Harst Jaspal S Kooner John C Chambers

Nat Genet 2015 11 21;47(11):1282-1293. Epub 2015 Sep 21.

Department of Epidemiology and Biostatistics, Imperial College London, London, UK.

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http://dx.doi.org/10.1038/ng.3405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719169PMC
November 2015

Effectiveness of Prior Use of Beta-Blockers for Preventing Adverse Influences of Severe Hypoglycemia in Patients With Diabetes: An Observational Study.

Medicine (Baltimore) 2015 Sep;94(39):e1629

From the Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo (TT, RYH, HK, MK, HN, RH); Division of General Medicine, Jichi Medical University Graduate School of Medicine, Shimotsuke (TT, MK); Department of Diabetes Research, Diabetes Research Center (RYH, MK, HN, MN); Department of Emergency Medicine and Critical Care, Center Hospital, National Center for Global Health and Medicine (AK); and First Department of Comprehensive Medicine, Saitama Medical Center, Jichi Medical University School of Medicine, Saitama, Japan (MK).

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http://dx.doi.org/10.1097/MD.0000000000001629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616818PMC
September 2015

High risk of abnormal QT prolongation in the early morning in diabetic and non-diabetic patients with severe hypoglycemia.

Ann Med 2015 May 10;47(3):238-44. Epub 2015 Apr 10.

Department of Diabetes, Endocrinology, and Metabolism, Center Hospital, National Center for Global Health and Medicine , Tokyo , Japan.

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http://dx.doi.org/10.3109/07853890.2015.1017528DOI Listing
May 2015

A newer conversion equation for the correlation between HbA1c and glycated albumin.

Endocr J 2014 28;61(6):553-60. Epub 2014 Mar 28.

Department of Endocrinology, Diabetes, and Metabolism, Center Hospital, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.

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April 2015

Seasonal variations of severe hypoglycemia in patients with type 1 diabetes mellitus, type 2 diabetes mellitus, and non-diabetes mellitus: clinical analysis of 578 hypoglycemia cases.

Medicine (Baltimore) 2014 Nov;93(23):e148

From the Department of Diabetes, Endocrinology, and Metabolism, National Center for Global Health and Medicine, Tokyo (TT, RY-H, HK, M Kishimoto, HN, RH); Division of General Medicine, Jichi Medical University Graduate School of Medicine, Tochigi (TT, M Kakei); Department of Diabetes Research, Diabetes Research Center (RY-H, M Kishimoto, HN, MN); Department of Emergency Medicine and Critical Care, Center Hospital, National Center for Global Health and Medicine, Tokyo (AK); and First Department of Comprehensive Medicine, Saitama Medical Center, Jichi Medical University School of Medicine, Saitama, Japan (M Kakei).

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http://dx.doi.org/10.1097/MD.0000000000000148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616344PMC
November 2014

Comment on Kramer et al. Glucagon response to oral glucose challenge in type 1 diabetes: lack of impact of euglycemia. Diabetes Care 2014;37:1076-1082.

Diabetes Care 2014 Oct;37(10):e224

Department of Diabetes, Endocrinology, and Metabolism, National Center for Global Health and Medicine, Tokyo, Japan

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http://dx.doi.org/10.2337/dc14-1500DOI Listing
October 2014

Prediction of response to GLP-1 receptor agonist therapy in Japanese patients with type 2 diabetes.

Diabetol Metab Syndr 2014 15;6(1):110. Epub 2014 Oct 15.

Department of Diabetes Research, Diabetes Research Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo, 162-8655 Japan.

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http://dx.doi.org/10.1186/1758-5996-6-110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4209043PMC
October 2014

Improvement of both fasting and postprandial glycemic control by the two-step addition of miglitol and mitiglinide to basal insulin therapy: a pilot study.

Diabetol Metab Syndr 2014 31;6:48. Epub 2014 Mar 31.

Department of Diabetes, Endocrinology and Metabolism, National Center for Global Health and Medicine Center Hospital, Tokyo, Japan ; Department of Diabetes Research, Diabetes Research Center, National, Center for Global Health and Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1186/1758-5996-6-48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4025538PMC
August 2014

A case of malignant insulinoma: successful control of glycemic fluctuation by replacing octreotide injections with octreotide LAR injections.

Endocr J 2013 11;60(8):951-7. Epub 2013 May 11.

Department of Diabetes and Metabolic Medicine, Center Hospital, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.

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March 2014

Autoimmune diabetes in HIV-infected patients on highly active antiretroviral therapy.

J Clin Endocrinol Metab 2010 Aug 19;95(8):4056-60. Epub 2010 May 19.

Department of Diabetes and Metabolic Medicine, AIDS Clinical Center, National Center for Global Health and Medicine, Toyama 1-21-1, Shinjuku-ku, Tokyo 162-8655, Japan.

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http://dx.doi.org/10.1210/jc.2010-0055DOI Listing
August 2010

Body mass index, fasting plasma glucose levels, and C-peptide levels as predictors of the future insulin use in Japanese type 2 diabetic patients.

Endocr J 2010 23;57(3):237-44. Epub 2009 Dec 23.

Department of Diabetes and Metabolic Medicine, International Medical Center of Japan, Toyama Hospital, Tokyo, Japan.

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June 2010

Hemoglobin variant HbE found in two South Asian diabetic patients.

Intern Med 2009 17;48(16):1397-401. Epub 2009 Aug 17.

Department of Diabetes and Metabolic Medicine, International Medical Center of Japan, Toyama Hospital, Tokyo.

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http://dx.doi.org/10.2169/internalmedicine.48.2219DOI Listing
April 2010

Primary aldosteronism associated with severe rhabdomyolysis due to profound hypokalemia.

Intern Med 2009 16;48(4):219-23. Epub 2009 Feb 16.

Department of Diabetes and Metabolic Medicine, International Medical Center of Japan, Tokyo.

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http://dx.doi.org/10.2169/internalmedicine.48.1444DOI Listing
May 2009

A case of fulminant type 1 diabetes associated with significant elevation of mumps titers.

Endocr J 2008 Jul 3;55(3):561-4. Epub 2008 Jun 3.

Department of Diabetes and Metabolic Medicine, International Medical Center of Japan, Tokyo, Japan.

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July 2008

Hypopituitarism caused by bilateral internal carotid artery aneurysms with a carotid-cavernous fistula.

Intern Med 2008 16;47(8):815-6. Epub 2008 Apr 16.

Department of Diabetes and Metabolic Medicine, International Medical Center of Japan, Tokyo.

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http://dx.doi.org/10.2169/internalmedicine.47.0897DOI Listing
June 2008

[Drug-induced diabetes].

Nihon Rinsho 2007 Oct;65 Suppl 8:584-8

Department of Endocrinology and Metabolism, International Medical Center of Japan.

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October 2007

Use of insulin glargine in Japanese patients with type 1 diabetes.

Intern Med 2007 2;46(13):937-43. Epub 2007 Jul 2.

Department of Endocrinology and Metabolism, Marunouchi Hospital attached to the Institute for Adult Diseases, Asahi Life Fondation, Tokyo.

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http://dx.doi.org/10.2169/internalmedicine.46.6467DOI Listing
August 2007

An elderly case of type 2 diabetes which developed in association with oral and esophageal candidiasis.

Intern Med 2007 2;46(7):387-90. Epub 2007 Apr 2.

Department of Endocrinology and Metabolism, International Medical Center of Japan, Tokyo, Japan.

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http://dx.doi.org/10.2169/internalmedicine.46.1898DOI Listing
May 2007

Genetic variations of the ABC transporter gene ABCC3 in a Japanese population.

Drug Metab Pharmacokinet 2007 Apr;22(2):129-35

Project Team for Pharmacogenetics, National Institute of Health Sciences, Tokyo, Japan.

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April 2007

Novel genetic variations and haplotypes of hepatocyte nuclear factor 4alpha (HNF4A) found in Japanese type II diabetic patients.

Drug Metab Pharmacokinet 2006 Aug;21(4):337-46

Project Team for Pharmacogenetics, National Institute of Health Sciences, Tokyo, Japan.

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August 2006

Four novel defective alleles and comprehensive haplotype analysis of CYP2C9 in Japanese.

Pharmacogenet Genomics 2006 Jul;16(7):497-514

Project Team for Pharmacogenetics, Division of Biochemistry and Immunochemistry, National Institute of Health Sciences, 1-18-1 Kamiyoga, Setagaya-ku, Tokyo 158-8501, Japan.

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http://pdfs.journals.lww.com/jpharmacogenetics/2006/07000/Fo
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http://dx.doi.org/10.1097/01.fpc.0000215069.14095.c6DOI Listing
July 2006

Genetic variations and haplotypes of CYP2C19 in a Japanese population.

Drug Metab Pharmacokinet 2005 Aug;20(4):300-7

Project Team for Pharmacogenetics, National Institute of Health Sciences, Tokyko, Japan.

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August 2005

Thiazolidinediones increase the number of platelets in immune thrombocytopenic purpura mice via inhibition of phagocytic activity of the reticulo-endothelial system.

Life Sci 2002 Sep;71(17):2037-52

Department of Endocrinology and Metabolism, Jichi Medical School, Omiya Medical Center, 1-847 Amanuma-cho, Saitama 330-8503, Japan.

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http://dx.doi.org/10.1016/s0024-3205(02)01950-1DOI Listing
September 2002

Ca2+-dependent dephosphorylation of kinesin heavy chain on beta-granules in pancreatic beta-cells. Implications for regulated beta-granule transport and insulin exocytosis.

J Biol Chem 2002 Jul 26;277(27):24232-42. Epub 2002 Apr 26.

Pacific Northwest Research Institute and Department of Pharmacology, University of Washington, Seattle, Washington 98112, USA.

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http://dx.doi.org/10.1074/jbc.M203345200DOI Listing
July 2002