Hiroshi Inoue

Hiroshi Inoue

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Hiroshi Inoue

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Clinical risk factors of stroke and major bleeding in patients with non-valvular atrial fibrillation under rivaroxaban: the EXPAND Study sub-analysis.

Heart Vessels 2019 Nov 24;34(11):1839-1851. Epub 2019 May 24.

Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, 1-1, Seiryomachi, Aoba-ku, Sendai, 980-8574, Miyagi, Japan.

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http://dx.doi.org/10.1007/s00380-019-01425-xDOI Listing
November 2019

Logical design of oral glucose ingestion pattern minimizing blood glucose in humans.

NPJ Syst Biol Appl 2019 2;5:31. Epub 2019 Sep 2.

1Molecular Genetic Research Laboratory, Graduate School of Science, The University of Tokyo, Tokyo, 113-0033 Japan.

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http://dx.doi.org/10.1038/s41540-019-0108-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718521PMC
September 2019

MAPK Erk5 in leptin receptor-expressing neurons controls body weight and systemic energy homeostasis in female mice.

Endocrinology 2019 Sep 25. Epub 2019 Sep 25.

Laboratory of Molecular Pharmacology, Division of Pharmaceutical Sciences, Kanazawa University Graduate School, Kanazawa, Ishikawa, Japan.

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http://dx.doi.org/10.1210/en.2019-00090DOI Listing
September 2019

Impact of Digitalis Use on Mortality in Japanese Patients With Non-Valvular Atrial Fibrillation - A Subanalysis of the J-RHYTHM Registry.

Circ J 2019 Jul 19;83(8):1644-1652. Epub 2019 Jun 19.

Division of Biostatistics and Clinical Epidemiology, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences.

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http://dx.doi.org/10.1253/circj.CJ-19-0267DOI Listing
July 2019

Citrus fruits induced swallow syncope with atrioventricular block or sinus arrest.

J Electrocardiol 2018 Jul - Aug;51(4):613-616. Epub 2018 Apr 18.

The Second Department of Internal Medicine, Graduate School of Medicine, University of Toyama, Toyama 930-0194, Japan.

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http://dx.doi.org/10.1016/j.jelectrocard.2018.04.012DOI Listing
May 2019

Nicotinic alpha-7 acetylcholine receptor deficiency exacerbates hepatic inflammation and fibrosis in a mouse model of non-alcoholic steatohepatitis.

J Diabetes Investig 2019 May 16;10(3):659-666. Epub 2018 Dec 16.

Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa, Japan.

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http://doi.wiley.com/10.1111/jdi.12964
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http://dx.doi.org/10.1111/jdi.12964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6497582PMC
May 2019

Time in Therapeutic Range and Disease Outcomes in Elderly Japanese Patients With Nonvalvular Atrial Fibrillation.

Circ J 2018 09 28;82(10):2510-2517. Epub 2018 Aug 28.

Division of Biostatistics and Clinical Epidemiology, University of Toyama, Graduate School of Medicine.

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https://www.jstage.jst.go.jp/article/circj/82/10/82_CJ-18-05
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http://dx.doi.org/10.1253/circj.CJ-18-0587DOI Listing
September 2018

Docosahexaenoic Acid Reduces Palmitic Acid-Induced Endoplasmic Reticulum Stress in Pancreatic Β Cells.

Kobe J Med Sci 2018 Sep 11;64(2):E43-E55. Epub 2018 Sep 11.

Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347050PMC
September 2018

Renal Dysfunction Affects Anticoagulation Control With Warfarin and Outcomes in Japanese Elderly Patients With Non-Valvular Atrial Fibrillation.

Circ J 2018 08 6;82(9):2277-2283. Epub 2018 Jul 6.

Division of Biostatistics and Clinical Epidemiology, University of Toyama, Graduate School of Medicine.

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http://dx.doi.org/10.1253/circj.CJ-18-0242DOI Listing
August 2018

Dietary mung bean protein reduces high-fat diet-induced weight gain by modulating host bile acid metabolism in a gut microbiota-dependent manner.

Biochem Biophys Res Commun 2018 07 19;501(4):955-961. Epub 2018 May 19.

Department of Applied Biological Science, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Fuchu-shi, Tokyo, 183-8509, Japan; AMED-CREST, Japan Agency for Medical Research and Development, Chiyoda-ku, Tokyo, 100-0004, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X183115
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http://dx.doi.org/10.1016/j.bbrc.2018.05.090DOI Listing
July 2018

Transcatheter aortic valve implantation in an elderly man with severe aortic stenosis and high surgical risk.

Nihon Ronen Igakkai Zasshi 2016 ;53(2):158-63

Second Department of Internal Medicine, University of Toyama.

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http://dx.doi.org/10.3143/geriatrics.53.158DOI Listing
March 2018

Successful Surgical Resection following Bronchial Artery Embolization in a Case of Lung Cancer Complicated with Massive Hemoptysis.

Case Rep Oncol 2018 Jan-Apr;11(1):125-130. Epub 2018 Feb 28.

Division of Haematology, Respiratory Medicine and Oncology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan.

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http://dx.doi.org/10.1159/000486954DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869584PMC
February 2018

Impact of creatinine clearance on outcomes in patients with non-valvular atrial fibrillation: a subanalysis of the J-RHYTHM Registry.

Eur Heart J Qual Care Clin Outcomes 2018 01;4(1):59-68

Division of Biostatistics and Clinical Epidemiology, University of Toyama Graduate School of Medicine and Pharmaceutical Sciences, 2630 Sugitani, Toyama-shi, Toyama 930-0194, Japan.

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http://dx.doi.org/10.1093/ehjqcco/qcx032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862022PMC
January 2018

Sirt2 facilitates hepatic glucose uptake by deacetylating glucokinase regulatory protein.

Nat Commun 2018 01 2;9(1):30. Epub 2018 Jan 2.

Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa, Ishikawa, 920-8641, Japan.

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http://dx.doi.org/10.1038/s41467-017-02537-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750207PMC
January 2018

Independent prognostic importance of respiratory instability and sympathetic nerve activity in patients with chronic heart failure.

J Cardiol 2017 Nov 22;70(5):476-483. Epub 2017 Apr 22.

The Second Department of Internal Medicine, Toyama University Hospital, Toyama City, Toyama, Japan.

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http://dx.doi.org/10.1016/j.jjcc.2017.02.011DOI Listing
November 2017

Nicorandil Attenuates Ischemia-Reperfusion Injury Via Inhibition of Norepinephrine Release From Cardiac Sympathetic Nerve Terminals.

Int Heart J 2017 Oct 30;58(5):787-793. Epub 2017 Sep 30.

Second Department of Internal Medicine, Graduate School of Medicine, University of Toyama.

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http://dx.doi.org/10.1536/ihj.16-391DOI Listing
October 2017

Latent pathogenicity of the G38S polymorphism of KCNE1 K channel modulator.

Heart Vessels 2017 Feb 2;32(2):186-192. Epub 2016 Jun 2.

Department of Legal Medicine, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.

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http://dx.doi.org/10.1007/s00380-016-0859-1DOI Listing
February 2017

Restrictive Lung Function Is Related to Sympathetic Hyperactivity in Patients With Heart Failure.

J Card Fail 2017 Feb 8;23(2):96-103. Epub 2016 Jun 8.

Second Department of Internal Medicine, Toyama University Hospital, Toyama, Japan.

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http://dx.doi.org/10.1016/j.cardfail.2016.06.001DOI Listing
February 2017

Heart rate control by carvedilol in Japanese patients with chronic atrial fibrillation: The AF Carvedilol study.

J Cardiol 2017 01 28;69(1):293-301. Epub 2016 Jun 28.

Clinical Planning Department, Daiichi Sankyo Co Ltd, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jjcc.2016.05.012DOI Listing
January 2017

Glycan region of GPI anchored-protein is required for cytocidal oligomerization of an anticancer parasporin-2, Cry46Aa1 protein, from Bacillus thuringiensis strain A1547.

J Invertebr Pathol 2017 01 15;142:71-81. Epub 2016 Nov 15.

Department of Chemistry, Faculty of Science, Kyushu University, Fukuoka 812-8581, Japan; Department of Bioscience and Bioinformatics, Kyushu Institute of Technology, Iizuka, Fukuoka 820-8502, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jip.2016.11.008DOI Listing
January 2017

Beneficial Effect of Non-Vitamin K Antagonist Oral Anticoagulants in Patients With Nonvalvular Atrial Fibrillation - Results of the J-RHYTHM Registry 2.

Circ J 2016 18;80(4):843-51. Epub 2016 Mar 18.

Department of Internal Medicine and Cardiology, Nippon Medical School, Tama-Nagayama Hospital.

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http://dx.doi.org/10.1253/circj.CJ-16-0066DOI Listing
December 2016

Central insulin-mediated regulation of hepatic glucose production [Review].

Authors:
Hiroshi Inoue

Endocr J 2016 8;63(1):1-7. Epub 2015 Oct 8.

Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa 920-8641, Japan.

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http://dx.doi.org/10.1507/endocrj.EJ15-0540DOI Listing
November 2016

The GCN5-CITED2-PKA signalling module controls hepatic glucose metabolism through a cAMP-induced substrate switch.

Nat Commun 2016 11 22;7:13147. Epub 2016 Nov 22.

Department of Molecular Metabolic Regulation, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.

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http://dx.doi.org/10.1038/ncomms13147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121418PMC
November 2016

Abnormal repolarization dynamics in a patient with KCNE1(G38S) who presented with torsades de pointes.

J Electrocardiol 2016 Jan-Feb;49(1):94-8. Epub 2015 Oct 14.

Second Department of Internal Medicine, Graduate School of Medicine, University of Toyama, Toyama, Japan.

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http://dx.doi.org/10.1016/j.jelectrocard.2015.10.002DOI Listing
October 2016

Use of warfarin in elderly patients with non-valvular atrial fibrillation -- subanalysis of the J-RHYTHM Registry.

Circ J 2015 1;79(11):2345-52. Epub 2015 Sep 1.

Department of Internal Medicine and Cardiology, Nippon Medical School, Tama-Nagayama Hospital.

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http://dx.doi.org/10.1253/circj.CJ-15-0621DOI Listing
August 2016

Waon therapy attenuates cardiac hypertrophy and promotes myocardial capillary growth in hypertensive rats: a comparative study with fluvastatin.

Heart Vessels 2016 Aug 19;31(8):1361-9. Epub 2015 Dec 19.

Second Department of Internal Medicine, Graduate School of Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan.

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http://dx.doi.org/10.1007/s00380-015-0779-5DOI Listing
August 2016

Right-to-left shunt through patent foramen ovale during off-pump coronary artery bypass.

J Thorac Cardiovasc Surg 2016 Jul 13;152(1):e21-2. Epub 2015 Dec 13.

Department of Cardiovascular Surgery, Juntendo University, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jtcvs.2015.12.011DOI Listing
July 2016

Impact of Body Mass Index on the Prognosis of Japanese Patients With Non-Valvular Atrial Fibrillation.

Am J Cardiol 2016 Jul 5;118(2):215-21. Epub 2016 May 5.

Division of Biostatistics and Clinical Epidemiology, University of Toyama, Graduate School of Medicine, Toyama, Japan.

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http://dx.doi.org/10.1016/j.amjcard.2016.04.036DOI Listing
July 2016

Regulation of Pancreatic β Cell Mass by Cross-Interaction between CCAAT Enhancer Binding Protein β Induced by Endoplasmic Reticulum Stress and AMP-Activated Protein Kinase Activity.

PLoS One 2015 19;10(6):e0130757. Epub 2015 Jun 19.

Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan; Division of Medical Chemistry, Department of Biophysics, Kobe University Graduate School of Health Sciences, Kobe, Japan.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0130757PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4474801PMC
May 2016

Coefficient of Variation of P-Wave Duration Is a Novel Atrial Heterogeneity Index to Predict Recurrence of Atrial Fibrillation After Catheter Ablation.

J Cardiovasc Electrophysiol 2016 05 11;27(5):542-8. Epub 2016 Feb 11.

Department of Internal Medicine, Saiseikai Toyama Hospital, Toyama, Japan.

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http://dx.doi.org/10.1111/jce.12920DOI Listing
May 2016

Thoracic Aortic Stent Migration to False Lumen in Aortic Dissection Detected by Intraoperative Transesophageal Echocardiography.

Anesth Analg 2016 Apr;122(4):963-6

From the *Department of Anesthesia, Sendai Kousei Hospital, Sendai City, Miyagi, Japan; and †Department of Anesthesiology, Tohoku University Hospital, Sendai City, Miyagi, Japan.

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http://dx.doi.org/10.1213/ANE.0000000000001132DOI Listing
April 2016

Differentiation of Slow-Slow Form of AVNRT from AVRT through a Posteroseptal Accessory Pathway by Retrograde P-Wave Amplitude.

Pacing Clin Electrophysiol 2016 Mar 12;39(3):241-9. Epub 2016 Jan 12.

Second Department of Internal Medicine, University of Toyama, Toyama, Japan.

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http://dx.doi.org/10.1111/pace.12794DOI Listing
March 2016

Secondary Prevention of Stroke with Warfarin in Patients with Nonvalvular Atrial Fibrillation: Subanalysis of the J-RHYTHM Registry.

J Stroke Cerebrovasc Dis 2016 Mar 22;25(3):585-99. Epub 2015 Dec 22.

Division of Biostatistics and Clinical Epidemiology, University of Toyama, Toyama, Japan.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2015.11.020DOI Listing
March 2016

Central Insulin Action Activates Kupffer Cells by Suppressing Hepatic Vagal Activation via the Nicotinic Alpha 7 Acetylcholine Receptor.

Cell Rep 2016 Mar 3;14(10):2362-74. Epub 2016 Mar 3.

Department of Physiology and Metabolism, Brain/Liver Interface Medicine Research Center, Kanazawa University, Kanazawa, Ishikawa 920-8641, Japan; Metabolism and Nutrition Research Unit, Institute for Frontier Science Initiative, Kanazawa University, Kanazawa, Ishikawa 920-8641, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.02.032DOI Listing
March 2016

Antiplatelet therapy in Japanese patients with atrial fibrillation without oral anticoagulants: Pooled analysis of Shinken Database, J-RHYTHM registry and Fushimi AF registry.

Int J Cardiol 2015 23;190:344-6. Epub 2015 Apr 23.

Second Department of Internal Medicine, University of Toyama, Graduate School of Medicine, Toyama, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2015.04.182DOI Listing
February 2016

Hepatocyte β-Klotho regulates lipid homeostasis but not body weight in mice.

FASEB J 2016 Feb 29;30(2):849-62. Epub 2015 Oct 29.

*Laboratory of Molecular Life Science, Foundation for Biomedical Research and Innovation, Kobe, Hyogo, Japan; Medical Innovation Center and Department of Pathology and Tumor Biology, Graduate School of Medicine, and Laboratory of Nutrition Chemistry, Graduate School of Agriculture, Kyoto University, Sakyo-ku, Kyoto, Japan; First Department of Internal Medicine, Nara Medical University, Kashihara, Nara, Japan; Department of Physiology and Metabolism, Brain/Liver Interface Medicine Research Center, College of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Ishikawa, Japan; and Department of Molecular Metabolic Regulation, Diabetes Research Center, Research Institute, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo, Japan

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http://dx.doi.org/10.1096/fj.15-274449DOI Listing
February 2016

Assessment of risk factors for bleeding in Japanese patients with non-valvular atrial fibrillation receiving warfarin treatment: A subanalysis of the J-RHYTHM Registry.

Int J Cardiol 2015 Dec 5;201:308-10. Epub 2015 Aug 5.

Division of Biostatistics and Clinical Epidemiology, University of Toyama School of Medicine, Toyama, Japan.

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http://dx.doi.org/10.1016/j.ijcard.2015.08.059DOI Listing
December 2015

Time-Dependent Changes in QT Dynamics after Initiation and Termination of Paroxysmal Atrial Fibrillation.

Pacing Clin Electrophysiol 2015 Dec 22;38(12):1418-24. Epub 2015 Sep 22.

Second Department of Internal Medicine, Graduate School of Medicine, University of Toyama, Toyama, Japan.

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http://dx.doi.org/10.1111/pace.12746DOI Listing
December 2015

Recurrent syncope in two patients with a sigmoid-shaped interventricular septum and no left ventricular hypertrophy.

J Arrhythm 2015 Dec 28;31(6):391-4. Epub 2015 May 28.

Second Department of Internal Medicine, Graduate School of Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan.

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http://dx.doi.org/10.1016/j.joa.2015.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4672037PMC
December 2015

Target intensity of anticoagulation with warfarin in Japanese patients with valvular atrial fibrillation – subanalysis of the J-RHYTHM Registry.

Circ J 2015 10;79(2):325-30. Epub 2014 Dec 10.

Department of Internal Medicine and Cardiology, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1253/circj.CJ-14-1057DOI Listing
November 2015

Amorphous Vanadium Oxide/Carbon Composite Positive Electrode for Rechargeable Aluminum Battery.

ACS Appl Mater Interfaces 2015 Nov 28;7(44):24385-9. Epub 2015 Oct 28.

Department of Applied Chemistry, Graduate School of Engineering, Osaka Prefecture University , Sakai, Osaka 599-8531, Japan.

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http://dx.doi.org/10.1021/acsami.5b06420DOI Listing
November 2015

Paternal allelic mutation at the Kcnq1 locus reduces pancreatic β-cell mass by epigenetic modification of Cdkn1c.

Proc Natl Acad Sci U S A 2015 Jul 22;112(27):8332-7. Epub 2015 Jun 22.

Division of Diabetes and Endocrinology, Department of Internal Medicine, Kobe University Graduate School of Medicine, Hyogo 650-0017, Japan; Division of Medical Chemistry, Department of Biophysics, Kobe University Graduate School of Health Sciences, Hyogo 654-0142, Japan;

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http://dx.doi.org/10.1073/pnas.1422104112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500236PMC
July 2015

Pubertal administration of antiserum against nerve growth factor regresses renal vascular remodeling in spontaneously hypertensive rats.

Clin Exp Pharmacol Physiol 2015 Jun;42(6):687-94

The Second Department of Internal Medicine, University of Toyama, Toyama, Japan.

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http://doi.wiley.com/10.1111/1440-1681.12411
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http://dx.doi.org/10.1111/1440-1681.12411DOI Listing
June 2015

Waon therapy improves quality of life as well as cardiac function and exercise capacity in patients with chronic heart failure.

Int Heart J 2015 27;56(2):203-8. Epub 2015 Feb 27.

Second Department of Internal Medicine, Graduate School of Medicine, University of Toyama.

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http://dx.doi.org/10.1536/ihj.14-266DOI Listing
May 2015

Growth arrest and DNA damage-inducible 34 regulates liver regeneration in hepatic steatosis in mice.

Hepatology 2015 Apr 23;61(4):1343-56. Epub 2015 Feb 23.

Department of Physiology and Metabolism, Brain/Liver Interface Medicine Research Center, Kanazawa University, Kanazawa, Japan.

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http://dx.doi.org/10.1002/hep.27619DOI Listing
April 2015

Warfarin anticoagulation intensity in Japanese nonvalvular atrial fibrillation patients: a J-RHYTHM Registry analysis.

J Cardiol 2015 Mar 26;65(3):175-7. Epub 2014 Aug 26.

Division of Biostatistics and Clinical Epidemiology, University of Toyama School of Medicine, Toyama, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S09145087140021
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http://dx.doi.org/10.1016/j.jjcc.2014.07.013DOI Listing
March 2015

Image Fusion for Radiosurgery, Neurosurgery and Hypofractionated Radiotherapy.

Cureus 2015 Mar 2;7(3):e252. Epub 2015 Mar 2.

Department of Radiation Oncology, Fukushima Medical University.

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http://dx.doi.org/10.7759/cureus.252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494462PMC
March 2015

Location of epicardial adipose tissue affects the efficacy of a combined dominant frequency and complex fractionated atrial electrogram ablation of atrial fibrillation.

Heart Rhythm 2015 Feb 22;12(2):257-65. Epub 2014 Oct 22.

Division of Cardiology, Gunma Prefectural Cardiovascular Center, Gunma, Japan.

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http://dx.doi.org/10.1016/j.hrthm.2014.10.020DOI Listing
February 2015

Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis.

Nat Commun 2014 Sep 19;5:4982. Epub 2014 Sep 19.

Department of Molecular Endocrinology and Metabolism, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo 113-8510, Japan.

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http://dx.doi.org/10.1038/ncomms5982DOI Listing
September 2014