Hironobu Ohmatsu

Hironobu Ohmatsu

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Hironobu Ohmatsu

Hironobu Ohmatsu

Publications by authors named "Hironobu Ohmatsu"

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Long-term results of S-1 plus cisplatin with concurrent thoracic radiotherapy for locally advanced non-small-cell lung cancer.

Cancer Chemother Pharmacol 2018 03 31;81(3):565-572. Epub 2018 Jan 31.

Department of Radiation Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1007/s00280-018-3530-yDOI Listing
March 2018

Switch maintenance chemotherapy using S-1 with or without bevacizumab in patients with advanced non-small cell lung cancer: a phase II study.

Lung Cancer 2017 06 1;108:66-71. Epub 2017 Mar 1.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2017.02.018DOI Listing
June 2017

Prognostic Factor Analysis in Patients With Small-Cell Lung Cancer Treated With Third-Line Chemotherapy.

Clin Lung Cancer 2016 11 16;17(6):581-587. Epub 2016 Jun 16.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1016/j.cllc.2016.05.022DOI Listing
November 2016

Clinical Impact of Gastric Acid-Suppressing Medication Use on the Efficacy of Erlotinib and Gefitinib in Patients With Advanced Non-Small-Cell Lung Cancer Harboring EGFR Mutations.

Clin Lung Cancer 2016 09 5;17(5):412-418. Epub 2016 Feb 5.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan; Juntendo University Graduate School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.cllc.2016.01.006DOI Listing
September 2016

Factors influencing the concordance of histological subtype diagnosis from biopsy and resected specimens of lung adenocarcinoma.

Lung Cancer 2016 Apr 22;94:1-6. Epub 2016 Jan 22.

Division of Pathology, Exploratory Oncology Research & Clinical Trial Center, National Cancer Center, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.01.009DOI Listing
April 2016

Unique intravascular tumor microenvironment predicting recurrence of lung squamous cell carcinoma.

J Cancer Res Clin Oncol 2016 Mar 31;142(3):593-600. Epub 2015 Oct 31.

Division of Pathology, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00432-015-2068-1DOI Listing
March 2016

RECIST progression patterns during EGFR tyrosine kinase inhibitor treatment of advanced non-small cell lung cancer patients harboring an EGFR mutation.

Lung Cancer 2015 Dec 9;90(3):477-83. Epub 2015 Oct 9.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2015.09.025DOI Listing
December 2015

Phase II study of amrubicin at a dose of 45 mg/m2 in patients with previously treated small-cell lung cancer.

Jpn J Clin Oncol 2015 Oct 31;45(10):941-6. Epub 2015 Jul 31.

Department of Thoracic Oncology, National Cancer Center Hospital, Tokyo.

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http://dx.doi.org/10.1093/jjco/hyv107DOI Listing
October 2015

Comparison of the expression levels of molecular markers among the peripheral area and central area of primary tumor and metastatic lymph node tumor in patients with squamous cell carcinoma of the lung.

J Cancer Res Clin Oncol 2015 Aug 9;141(8):1417-25. Epub 2015 Jan 9.

Pathology Division, Department of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, 277-8577, Japan.

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http://link.springer.com/10.1007/s00432-015-1912-7
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http://dx.doi.org/10.1007/s00432-015-1912-7DOI Listing
August 2015

Presence of podoplanin-positive cancer-associated fibroblasts in surgically resected primary lung adenocarcinoma predicts a shorter progression-free survival period in patients with recurrences who received platinum-based chemotherapy.

J Cancer Res Clin Oncol 2015 Jul 2;141(7):1163-70. Epub 2014 Dec 2.

Pathology Division, Department of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://dx.doi.org/10.1007/s00432-014-1891-0DOI Listing
July 2015

Docetaxel for platinum-refractory advanced thymic carcinoma.

Jpn J Clin Oncol 2015 Jul 2;45(7):665-9. Epub 2015 Apr 2.

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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http://dx.doi.org/10.1093/jjco/hyv046DOI Listing
July 2015

Second-line docetaxel for patients with platinum-refractory advanced non-small cell lung cancer and interstitial pneumonia.

Cancer Chemother Pharmacol 2015 Jul 15;76(1):69-74. Epub 2015 May 15.

Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://link.springer.com/10.1007/s00280-015-2775-y
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http://dx.doi.org/10.1007/s00280-015-2775-yDOI Listing
July 2015

Vinorelbine and cisplatin in patients with advanced non-small cell lung cancer with interstitial pneumonia.

Anticancer Res 2015 Mar;35(3):1697-701

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Japan.

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March 2015

Low-dose irinotecan as a second-line chemotherapy for recurrent small cell lung cancer.

Jpn J Clin Oncol 2014 Sep 23;44(9):846-51. Epub 2014 Jul 23.

Department of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan.

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http://dx.doi.org/10.1093/jjco/hyu094DOI Listing
September 2014

Therapeutic priority of the PI3K/AKT/mTOR pathway in small cell lung cancers as revealed by a comprehensive genomic analysis.

J Thorac Oncol 2014 Sep;9(9):1324-31

*Division of Thoracic Oncology, National Cancer Center Hospital East; †Exploratory Oncology Research and Clinical Trial Center, National Cancer Center; ‡Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East; §Division of Thoracic Surgery, National Cancer Center Hospital East, Kashiwa, Japan; and ‖Division of Genome Biology, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan.

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http://dx.doi.org/10.1097/JTO.0000000000000250DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154841PMC
September 2014

Protective effect of magnesium preloading on cisplatin-induced nephrotoxicity: a retrospective study.

Jpn J Clin Oncol 2014 Apr 5;44(4):346-54. Epub 2014 Feb 5.

*Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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https://academic.oup.com/jjco/article-lookup/doi/10.1093/jjc
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http://dx.doi.org/10.1093/jjco/hyu004DOI Listing
April 2014

Aldehyde dehydrogenase 1 expression in cancer cells could have prognostic value for patients with non-small cell lung cancer who are treated with neoadjuvant therapy: identification of prognostic microenvironmental factors after chemoradiation.

Pathol Int 2013 Dec;63(12):599-606

Division of Pathology, Research Center for Innovative Oncology, National Cancer Center, Hospital East, Kashiwa, Chiba, Japan; Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan; Juntendo University Graduate School of Medicine, Tokyo, Japan.

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http://dx.doi.org/10.1111/pin.12122DOI Listing
December 2013

Identification of prognostic immunophenotypic features in cancer stromal cells of high-grade neuroendocrine carcinomas of the lung.

J Cancer Res Clin Oncol 2013 Nov 7;139(11):1869-78. Epub 2013 Sep 7.

Pathology Division, Department of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, 6-5-1, Kashiwanoha, Kashiwa-City, Chiba, 277-8577, Japan.

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http://link.springer.com/content/pdf/10.1007/s00432-013-1502
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http://link.springer.com/10.1007/s00432-013-1502-5
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http://dx.doi.org/10.1007/s00432-013-1502-5DOI Listing
November 2013

Solid predominant histology predicts EGFR tyrosine kinase inhibitor response in patients with EGFR mutation-positive lung adenocarcinoma.

J Cancer Res Clin Oncol 2013 Oct 22;139(10):1691-700. Epub 2013 Aug 22.

Division of Pathology, Research Center for Innovative Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, 277-8577, Japan.

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http://link.springer.com/content/pdf/10.1007/s00432-013-1495
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http://link.springer.com/10.1007/s00432-013-1495-0
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http://dx.doi.org/10.1007/s00432-013-1495-0DOI Listing
October 2013

Renal toxicity caused by brand-name versus generic cisplatin: a comparative analysis.

Jpn J Clin Oncol 2013 Apr 26;43(4):390-5. Epub 2013 Feb 26.

Division of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan.

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http://dx.doi.org/10.1093/jjco/hyt020DOI Listing
April 2013

Safety and efficacy of platinum agents plus etoposide for patients with small cell lung cancer with interstitial lung disease.

Anticancer Res 2013 Mar;33(3):1175-9

Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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March 2013

Feasibility study of zoledronic acid plus cisplatin-docetaxel as first-line treatment for advanced non-small cell lung cancer with bone metastases.

Anticancer Res 2012 Sep;32(9):4131-5

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba 277-8577, Japan.

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September 2012

Characterization of the immunophenotype of the tumor budding and its prognostic implications in squamous cell carcinoma of the lung.

Lung Cancer 2012 Jun 6;76(3):423-30. Epub 2011 Dec 6.

Pathology Division, Research Center for Innovative Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2011.11.010DOI Listing
June 2012

Clinical features of unresectable high-grade lung neuroendocrine carcinoma diagnosed using biopsy specimens.

Lung Cancer 2012 Mar 13;75(3):368-73. Epub 2011 Sep 13.

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2011.08.012DOI Listing
March 2012

Risk factors associated with fatal pulmonary hemorrhage in locally advanced non-small cell lung cancer treated with chemoradiotherapy.

BMC Cancer 2012 Jan 20;12:27. Epub 2012 Jan 20.

Department of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1186/1471-2407-12-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293744PMC
January 2012

Development of Cushing's syndrome during effective chemotherapy for small cell lung cancer.

Intern Med 2011 15;50(4):335-8. Epub 2011 Feb 15.

Thoracic Oncology Division, National Cancer Center Hospital East, Japan.

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http://dx.doi.org/10.2169/internalmedicine.50.4127DOI Listing
June 2011

Clinical outcome of small cell lung cancer with pericardial effusion but without distant metastasis.

J Thorac Oncol 2011 Apr;6(4):796-800

Division of Thoracic Oncology and †Radiation Oncology, National Cancer Center Hospital East, Chiba, Japan.

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http://dx.doi.org/10.1097/JTO.0b013e318208ec77DOI Listing
April 2011

Re-challenge chemotherapy for relapsed non-small-cell lung cancer.

Lung Cancer 2010 Sep 13;69(3):315-8. Epub 2010 Jan 13.

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2009.11.016DOI Listing
September 2010

Severe interstitial lung disease associated with amrubicin treatment.

J Thorac Oncol 2010 Sep;5(9):1435-8

Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1097/JTO.0b013e3181e369a8DOI Listing
September 2010

Hypertrophic pulmonary osteoarthropathy as a paraneoplastic manifestation of lung cancer.

J Thorac Oncol 2010 Jul;5(7):976-80

Department of Internal Medicine 3, Oita University Faculty of Medicine, Yufu City, Oita, Japan.

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http://dx.doi.org/10.1097/JTO.0b013e3181dc1f3cDOI Listing
July 2010

Trends in chemotherapy for elderly patients with advanced non-small-cell lung cancer.

Respir Med 2010 Mar 12;104(3):434-9. Epub 2009 Nov 12.

Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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http://dx.doi.org/10.1016/j.rmed.2009.10.020DOI Listing
March 2010

A phase I study of gemcitabine and carboplatin in patients with advanced non-small cell lung cancer and a performance status of 2.

Jpn J Clin Oncol 2009 Sep 11;39(9):576-81. Epub 2009 Jun 11.

Division of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan.

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http://dx.doi.org/10.1093/jjco/hyp061DOI Listing
September 2009

Mutational status of EGFR and KIT in thymoma and thymic carcinoma.

Lung Cancer 2008 Dec 29;62(3):316-20. Epub 2008 Apr 29.

Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2008.03.013DOI Listing
December 2008

Clinical outcome of chemoradiation therapy in patients with limited-disease small cell lung cancer with ipsilateral pleural effusion.

J Thorac Oncol 2008 Jul;3(7):723-7

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1097/JTO.0b013e31817c606aDOI Listing
July 2008

Phase II trial of carboplatin and paclitaxel in non-small cell lung cancer patients previously treated with chemotherapy.

Lung Cancer 2007 Oct 4;58(1):73-9. Epub 2007 Jun 4.

Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S016950020700262
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http://dx.doi.org/10.1016/j.lungcan.2007.04.015DOI Listing
October 2007

Detection of unsuspected distant metastases and/or regional nodes by FDG-PET [corrected] scan in apparent limited-disease small-cell lung cancer.

Lung Cancer 2007 Sep 29;57(3):328-33. Epub 2007 May 29.

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwanoha 6-5-1, Kashiwa, Chiba 277-8577, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2007.04.001DOI Listing
September 2007

Randomized trial of drip infusion versus bolus injection of vinorelbine for the control of local venous toxicity.

Lung Cancer 2007 Mar 28;55(3):337-41. Epub 2006 Nov 28.

Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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http://dx.doi.org/10.1016/j.lungcan.2006.10.016DOI Listing
March 2007

Interstitial shadow on chest CT is associated with the onset of interstitial lung disease caused by chemotherapeutic drugs.

Jpn J Clin Oncol 2006 May 15;36(5):269-73. Epub 2006 May 15.

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwanoha 6-5-1, Kashiwa, Chiba 277-8577, Japan.

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https://academic.oup.com/jjco/article-lookup/doi/10.1093/jjc
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http://dx.doi.org/10.1093/jjco/hyl021DOI Listing
May 2006

First-line single agent treatment with gefitinib in patients with advanced non-small-cell lung cancer: a phase II study.

J Clin Oncol 2006 Jan;24(1):64-9

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1200/JCO.2005.02.5825DOI Listing
January 2006

Limited resection trial for pulmonary ground-glass opacity nodules: fifty-case experience.

J Thorac Cardiovasc Surg 2005 May;129(5):991-6

Department of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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http://linkinghub.elsevier.com/retrieve/pii/S002252230401145
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http://dx.doi.org/10.1016/j.jtcvs.2004.07.038DOI Listing
May 2005

High body mass index correlates with increased risk of venous irritation by vinorelbine infusion.

Jpn J Clin Oncol 2004 Apr;34(4):206-9

Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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http://dx.doi.org/10.1093/jjco/hyh029DOI Listing
April 2004

Randomized trial of oral versus intravenous antibiotics in low-risk febrile neutropenic patients with lung cancer.

Jpn J Clin Oncol 2004 Feb;34(2):69-73

Division of Thoracic Oncology, National Cancer Center Hospital East, Chiba, Japan.

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http://dx.doi.org/10.1093/jjco/hyh019DOI Listing
February 2004

Example-based assisting approach for pulmonary nodule classification in three-dimensional thoracic computed tomography images.

Acad Radiol 2003 Dec;10(12):1402-15

Department of Optical Science and Technology, University of Tokushima, Minamijosanjima-cho, 2-1, Tokushima 770-8506, Japan.

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http://dx.doi.org/10.1016/s1076-6332(03)00507-5DOI Listing
December 2003

Weekly chemotherapy with cisplatin, vincristine, doxorubicin, and etoposide is an effective treatment for advanced thymic carcinoma.

Cancer 2003 Sep;98(5):926-31

Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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http://dx.doi.org/10.1002/cncr.11606DOI Listing
September 2003

Cushing's syndrome associated with adenocarcinoma of the lung.

Intern Med 2003 Sep;42(9):831-3

Thoracic Oncology Division, National Cancer Center Hospital East, Kashiwa, Chiba.

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http://dx.doi.org/10.2169/internalmedicine.42.831DOI Listing
September 2003

Combination second-line chemotherapy with gemcitabine and docetaxel for recurrent non-small-cell lung cancer after platinum-containing chemotherapy: a phase I/II trial.

Cancer Chemother Pharmacol 2003 Jul 24;52(1):19-24. Epub 2003 Apr 24.

Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwanoha 6-5-1, Kashiwa, 277-8577 Chiba, Japan.

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http://dx.doi.org/10.1007/s00280-003-0618-8DOI Listing
July 2003

Calcification in large cell neuroendocrine carcinoma of the lung.

Jpn J Clin Oncol 2003 Jan;33(1):10-3

Pathology Division, National Cancer Center Research Institute East and Division of Thoracic Oncology, National Cancer Center Hospital East, Kashiwa, Chiba, Japan.

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http://dx.doi.org/10.1093/jjco/hyg006DOI Listing
January 2003

[Lung cancer screening using low-dose helical CT].

Nihon Rinsho 2002 May;60 Suppl 5:653-6

Division of Thoracic Oncology, National Cancer Center Hospital East.

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May 2002

Phase II study of docetaxel and cisplatin administered as three consecutive weekly infusions for advanced non-small cell lung cancer.

Lung Cancer 2002 Feb;35(2):209-14

Division of Thoracic Oncology, National Cancer Center Hospital East, 6-5-1 Kashiwanoha, Kashiwa, Chiba 277-8577, Japan.

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http://dx.doi.org/10.1016/s0169-5002(01)00328-2DOI Listing
February 2002

Screening for lung cancer with low-dose helical computed tomography: anti-lung cancer association project.

J Clin Oncol 2002 Feb;20(4):911-20

Cancer Information and Epidemiology Division, National Cancer Center Research Institute, National Cancer Center Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1200/JCO.2002.20.4.911DOI Listing
February 2002