Publications by authors named "Hiromitsu Kumada"

475Publications

Virologic analysis of tenofovir resistance in a patient with chronic hepatitis B experiencing viral breakthrough during combination treatment with tenofovir disoproxil fumarate and entecavir.

Authors:
Fumitaka Suzuki Hitomi Sezaki Tetsuya Hosaka Yoshiyuki Suzuki Shunichiro Fujiyama Yusuke Kawamura Norio Akuta Masahiro Kobayashi Satoshi Saitoh Yasuji Arase Kenji Ikeda Mariko Kobayashi Rie Mineta Yukiko Suzuki Hiromitsu Kumada

Hepatol Res 2021 Jan 18. Epub 2021 Jan 18.

Department of Hepatology, Toranomon Hospital, Tokyo, Japan.

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January 2021

Lenvatinib-Transarterial Chemoembolization Sequential Therapy as an Effective Treatment at Progression during Lenvatinib Therapy for Advanced Hepatocellular Carcinoma.

Authors:
Yusuke Kawamura Masahiro Kobayashi Junichi Shindoh Yuta Kobayashi Satoshi Okubo Licht Tominaga Akira Kajiwara Kayoko Kasuya Soichi Iritani Shunichiro Fujiyama Tetsuya Hosaka Satoshi Saitoh Hitomi Sezaki Norio Akuta Fumitaka Suzuki Yoshiyuki Suzuki Kenji Ikeda Yasuji Arase Masaji Hashimoto Tokuyo Kozuka Hiromitsu Kumada

Liver Cancer 2020 Dec 30;9(6):756-770. Epub 2020 Oct 30.

Department of Hepatology, Toranomon Hospital, Tokyo, Japan.

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December 2020

An encapsulated bulky abdominal abscess due to amoeba.

Authors:
Soichi Iritani Yusuke Kawamura Daiki Yamashige Nozomu Muraishi Akira Kajiwara Shunichiro Fujiyama Hitomi Sezaki Tetsuya Hosaka Norio Akuta Masahiro Kobayashi Mariko Kobayashi Satoshi Saitoh Fumitaka Suzuki Yasuji Arase Kenji Ikeda Yoshiyuki Suzuki Hiromitsu Kumada

Clin J Gastroenterol 2021 Jan 11. Epub 2021 Jan 11.

Department of Hepatology, Toranomon Hospital and Okinaka Memorial Institute for Medical Research, Tokyo, Japan.

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January 2021

Potential of ultra-highly sensitive immunoassays for hepatitis B surface and core-related antigens in patients with or without development of hepatocellular carcinoma after hepatitis B surface antigen seroclearance.

Authors:
Fumitaka Suzuki Tetsuya Hosaka Masayasu Imaizumi Mariko Kobayashi Chiharu Ohue Yoshiyuki Suzuki Shunichiro Fujiyama Yusuke Kawamura Hitomi Sezaki Norio Akuta Masahiro Kobayashi Satoshi Saitoh Yasuji Arase Kenji Ikeda Hiromitsu Kumada

Hepatol Res 2020 Dec 3. Epub 2020 Dec 3.

Department of Hepatology, Toranomon Hospital, Tokyo, Japan.

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December 2020

Potential and Clinical Significance of 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography for Evaluating Liver Cancer Response to Lenvatinib Treatment.

Authors:
Daiki Yamashige Yusuke Kawamura Masahiro Kobayashi Junichi Shindoh Yuta Kobayashi Satoshi Okubo Nozomu Muraishi Akira Kajiwara Soichi Iritani Shunichiro Fujiyama Tetsuya Hosaka Satoshi Saitoh Hitomi Sezaki Norio Akuta Fumitaka Suzuki Yoshiyuki Suzuki Kenji Ikeda Yasuji Arase Masaji Hashimoto Hiromitsu Kumada

Oncology 2020 Nov 18:1-8. Epub 2020 Nov 18.

Department of Hepatology, Toranomon Hospital, Tokyo, Japan.

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November 2020

Non-invasive predictors of prognosis of Asian patients with histopathologically-confirmed lean nonalcoholic fatty liver disease.

Authors:
Soichi Iritani Norio Akuta Yusuke Kawamura Akira Kajiwara Kayoko Kasuya Shunichiro Fujiyama Hitomi Sezaki Tetsuya Hosaka Masahiro Kobayashi Mariko Kobayashi Satoshi Saito Fumitaka Suzuki Yasuji Arase Kenji Ikeda Yoshiyuki Suzuki Hiromitsu Kumada

BMC Gastroenterol 2020 Nov 4;20(1):368. Epub 2020 Nov 4.

Department of Hepatology, Toranomon Hospital and Okinaka Memorial Institute for Medical Research, 2-2-2 Toranomon, Minato-ku, Tokyo, 105-8470, Japan.

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November 2020

PNPLA3 and HLA-DQB1 polymorphisms are associated with hepatocellular carcinoma after hepatitis C virus eradication.

Authors:
Daiki Miki Tomoyuki Akita Akemi Kurisu Tomokazu Kawaoka Tomoaki Nakajima Shuhei Hige Yoshiyasu Karino Hidenori Toyoda Takashi Kumada Masataka Tsuge Akira Hiramatsu Michio Imamura Hiroshi Aikata Clair Nelson Hayes Koichi Honda Masataka Seike Norio Akuta Mariko Kobayashi Hiromitsu Kumada Junko Tanaka Kazuaki Chayama

J Gastroenterol 2020 Dec 15;55(12):1162-1170. Epub 2020 Oct 15.

Department of Gastroenterology and Metabolism, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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December 2020

TERT Promoter Mutation in Serum Cell-Free DNA Is a Diagnostic Marker of Primary Hepatocellular Carcinoma in Patients with Nonalcoholic Fatty Liver Disease.

Authors:
Norio Akuta Yusuke Kawamura Mariko Kobayashi Yasuji Arase Satoshi Saitoh Shunichiro Fujiyama Hitomi Sezaki Tetsuya Hosaka Masahiro Kobayashi Yoshiyuki Suzuki Fumitaka Suzuki Kenji Ikeda Hiromitsu Kumada

Oncology 2020 Sep 30:1-10. Epub 2020 Sep 30.

Department of Hepatology, Toranomon Hospital and Okinaka Memorial Institute for Medical Research, Tokyo, Japan.

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September 2020

Efficacy and Safety of Ramucirumab in Patients with Unresectable Hepatocellular Carcinoma with Progression after Treatment with Lenvatinib.

Authors:
Kayoko Kasuya Yusuke Kawamura Masahiro Kobayashi Junichi Shindoh Yuta Kobayashi Akira Kajiwara Soichi Iritani Shunichiro Fujiyama Tetsuya Hosaka Satoshi Saitoh Hitomi Sezaki Norio Akuta Fumitaka Suzuki Yoshiyuki Suzuki Kenji Ikeda Yasuji Arase Yuichiro Eguchi Masaji Hashimoto Hiromitsu Kumada

Intern Med 2020 Sep 19. Epub 2020 Sep 19.

Department of Hepatology, Toranomon Hospital, Japan.

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September 2020

Effects of alcohol consumption on multiple hepatocarcinogenesis in patients with fatty liver disease.

Authors:
Yorinari Ochiai Yusuke Kawamura Masahiro Kobayashi Junichi Shindoh Yuta Kobayashi Satoshi Okubo Nozomu Muraishi Akira Kajiwara Soichi Iritani Shunichiro Fujiyama Tetsuya Hosaka Satoshi Saitoh Hitomi Sezaki Norio Akuta Fumitaka Suzuki Yoshiyuki Suzuki Kenji Ikeda Yasuji Arase Masaji Hashimoto Hiromitsu Kumada

Hepatol Res 2021 Jan 1;51(1):62-68. Epub 2020 Oct 1.

Department of Hepatology, Toranomon Hospital, Tokyo, Japan.

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January 2021

Phase Ib Study of Lenvatinib Plus Pembrolizumab in Patients With Unresectable Hepatocellular Carcinoma.

Authors:
Richard S Finn Masafumi Ikeda Andrew X Zhu Max W Sung Ari D Baron Masatoshi Kudo Takuji Okusaka Masahiro Kobayashi Hiromitsu Kumada Shuichi Kaneko Marc Pracht Konstantin Mamontov Tim Meyer Tomoki Kubota Corina E Dutcus Kenichi Saito Abby B Siegel Leonid Dubrovsky Kalgi Mody Josep M Llovet

J Clin Oncol 2020 Sep 27;38(26):2960-2970. Epub 2020 Jul 27.

Liver Cancer Program, Division of Liver Diseases, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY.

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September 2020

Undifferentiated carcinoma of the liver demonstrated by contrast-enhanced ultrasonography.

Authors:
Nobuhiko Ogasawara Satoshi Saitoh Fumitaka Suzuki Keiichi Kinowaki Jun Masuda Hideyuki Denpou Norio Akuta Shunichiro Fujiyama Yusuke Kawamura Hitomi Sezaki Tetsuya Hosaka Masahiro Kobayashi Yoshiyuki Suzuki Yasuji Arase Kenji Ikeda Yuji Miura Toshimi Takano Hiromitsu Kumada

Clin J Gastroenterol 2020 Dec 10;13(6):1225-1232. Epub 2020 Jul 10.

Department of Hepatology, Toranomon Hospital, 2-2-2 Toranomon, Minato-ku, Tokyo, 105-0001, Japan.

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December 2020

Pretreatment Heterogeneous Enhancement Pattern of Hepatocellular Carcinoma May Be a Useful New Predictor of Early Response to Lenvatinib and Overall Prognosis.

Authors:
Yusuke Kawamura Masahiro Kobayashi Junichi Shindoh Yuta Kobayashi Kayoko Kasuya Tomoya Sano Shunichiro Fujiyama Tetsuya Hosaka Satoshi Saitoh Hitomi Sezaki Norio Akuta Fumitaka Suzuki Yoshiyuki Suzuki Kenji Ikeda Yasuji Arase Masaji Hashimoto Hiromitsu Kumada

Liver Cancer 2020 Jun 4;9(3):275-292. Epub 2020 Feb 4.

Department of Hepatology, Toranomon Hospital, Tokyo, Japan.

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June 2020

Steatohepatitic Variant of Hepatocellular Carcinoma Is Associated With Both Alcoholic Steatohepatitis and Nonalcoholic Steatohepatitis: A Study of 2 Cohorts With Molecular Insights.

Authors:
Jia Qin Takaaki Higashi Shigeki Nakagawa Naoto Fujiwara Yo-Ichi Yamashita Toru Beppu Hideo Baba Masahiro Kobayashi Hiromitsu Kumada Ganesh Gunasekaran Thomas D Schiano Swan N Thung Maria Isabel Fiel Yujin Hoshida Stephen C Ward

Am J Surg Pathol 2020 10;44(10):1406-1412

The Department of Pathology, Molecular, and Cell-Based Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY.

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October 2020

Diagnosis and Resection Treatment of Triplet Hepatocellular Carcinomas with a non-B non-C Background in a Middle Aged Man over a Period of 6-years.

Authors:
Akira Kajiwara Keiichi Kinowaki Norio Akuta Kayoko Kasuya Nozomu Muraishi Soichi Iritani Yusuke Kawamura Shunichiro Fujiyama Hitomi Sezaki Tetsuya Hosaka Satoshi Saitoh Masahiro Kobayashi Mariko Kobayashi Yasuji Arase Kenji Ikeda Fumitaka Suzuki Hiromitsu Kumada Yoshiyuki Suzuki

Intern Med 2020 Oct 23;59(20):2511-2516. Epub 2020 Jun 23.

Department of Hepatology, Toranomon Hospital, Japan.

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October 2020

Fulminant Hepatitis due to de novo Hepatitis B after Cord Blood Transplantation Rescued by Medical Treatment.

Authors:
Tomoya Sano Norio Akuta Yoshiyuki Suzuki Kayoko Kasuya Shunichiro Fujiyama Yusuke Kawamura Hitomi Sezaki Tetsuya Hosaka Satoshi Saitoh Masahiro Kobayashi Fumitaka Suzuki Mariko Kobayashi Yasuji Arase Kenji Ikeda Hiromitsu Kumada

Intern Med 2020 15;59(12):1519-1524. Epub 2020 Jun 15.

Department of Hepatology, Toranomon Hospital, Japan.

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October 2020

SGLT2 Inhibitor Treatment Outcome in Nonalcoholic Fatty Liver Disease Complicated with Diabetes Mellitus: The Long-term Effects on Clinical Features and Liver Histopathology.

Authors:
Norio Akuta Yusuke Kawamura Shunichiro Fujiyama Hitomi Sezaki Tetsuya Hosaka Masahiro Kobayashi Mariko Kobayashi Satoshi Saitoh Fumitaka Suzuki Yoshiyuki Suzuki Yasuji Arase Kenji Ikeda Hiromitsu Kumada

Intern Med 2020 Aug 23;59(16):1931-1937. Epub 2020 May 23.

Department of Hepatology, Toranomon Hospital and Okinaka Memorial Institute for Medical Research, Japan.

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August 2020

Detection of TERT promoter mutation in serum cell-free DNA using wild-type blocking PCR combined with Sanger sequencing in hepatocellular carcinoma.

Authors:
Norio Akuta Fumitaka Suzuki Mariko Kobayashi Shunichiro Fujiyama Yusuke Kawamura Hitomi Sezaki Tetsuya Hosaka Masahiro Kobayashi Satoshi Saitoh Yasuji Arase Kenji Ikeda Yoshiyuki Suzuki Hiromitsu Kumada

J Med Virol 2020 Feb 26. Epub 2020 Feb 26.

Department of Hepatology, Toranomon Hospital and Okinaka Memorial Institute for Medical Research, Tokyo, Japan.

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February 2020

F-Fluorodeoxyglucose Uptake in Hepatocellular Carcinoma as a Useful Predictor of an Extremely Rapid Response to Lenvatinib.

Authors:
Yusuke Kawamura Masahiro Kobayashi Junichi Shindoh Yuta Kobayashi Kayoko Kasuya Tomoya Sano Shunichiro Fujiyama Tetsuya Hosaka Satoshi Saitoh Hitomi Sezaki Norio Akuta Fumitaka Suzuki Yoshiyuki Suzuki Kenji Ikeda Yasuji Arase Masaji Hashimoto Hiromitsu Kumada

Liver Cancer 2020 Jan 13;9(1):84-92. Epub 2019 Nov 13.

aDepartment of Hepatology, Toranomon Hospital, Tokyo, Japan.

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January 2020

Circulating MicroRNA-122 and Fibrosis Stage Predict Mortality of Japanese Patients With Histopathologically Confirmed NAFLD.

Authors:
Norio Akuta Yusuke Kawamura Yasuji Arase Satoshi Saitoh Shunichiro Fujiyama Hitomi Sezaki Tetsuya Hosaka Masahiro Kobayashi Mariko Kobayashi Yoshiyuki Suzuki Fumitaka Suzuki Kenji Ikeda Hiromitsu Kumada

Hepatol Commun 2020 Jan 5;4(1):66-76. Epub 2019 Nov 5.

Department of Hepatology Toranomon Hospital and Okinaka Memorial Institute for Medical Research Tokyo Japan.

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January 2020