Hiroko Tsutsui

Hiroko Tsutsui

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Hiroko Tsutsui

Publications by authors named "Hiroko Tsutsui"

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ASC and NLRP3 maintain innate immune homeostasis in the airway through an inflammasome-independent mechanism.

Mucosal Immunol 2019 Sep 5;12(5):1092-1103. Epub 2019 Jul 5.

Department of Microbiology, Kyoto University Graduate School of Medicine, Kyoto, 606-8501, Japan.

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http://dx.doi.org/10.1038/s41385-019-0181-1DOI Listing
September 2019

The Effect of Daikenchuto, Japanese Herbal Medicine, on Adhesion Formation Induced by Cecum Cauterization and Cecum Abrasion in Mice.

Biol Pharm Bull 2019 ;42(2):179-186

Department of Surgery, Division of Hepatobiliary Pancreas Surgery, Hyogo College of Medicine.

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http://dx.doi.org/10.1248/bpb.b18-00543DOI Listing
July 2019

Caffeine-stimulated muscle IL-6 mediates alleviation of non-alcoholic fatty liver disease.

Biochim Biophys Acta Mol Cell Biol Lipids 2019 03 12;1864(3):271-280. Epub 2018 Dec 12.

Key Laboratory of Pu-erh Tea Science, the Ministry of Education, Yunnan Agricultural University, Kunming 650201, China; State Key Laboratory for Conservation and Utilization of Bio-Resources in Yunnan, Kunming, China; Pu'erh Tea Research Institute, Pu'erh, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13881981183037
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http://dx.doi.org/10.1016/j.bbalip.2018.12.003DOI Listing
March 2019

Interleukin-18 in Health and Disease.

Int J Mol Sci 2019 Feb 2;20(3). Epub 2019 Feb 2.

Department of Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan.

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http://dx.doi.org/10.3390/ijms20030649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387150PMC
February 2019

Pu'erh tea extract-mediated protection against hepatosteatosis and insulin resistance in mice with diet-induced obesity is associated with the induction of de novo lipogenesis in visceral adipose tissue.

J Gastroenterol 2017 Dec 31;52(12):1240-1251. Epub 2017 Mar 31.

Key Laboratory of Pu-erh Tea Science, The Ministry of Education, Yunnan Agricultural University, Kunming, 650201, China.

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http://dx.doi.org/10.1007/s00535-017-1332-3DOI Listing
December 2017

Inflammasome and Fas-Mediated IL-1β Contributes to Th17/Th1 Cell Induction in Pathogenic Bacterial Infection In Vivo.

J Immunol 2017 08 3;199(3):1122-1130. Epub 2017 Jul 3.

Department of Microbiology, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan.

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http://dx.doi.org/10.4049/jimmunol.1601373DOI Listing
August 2017

Caspase-1 deficiency promotes high-fat diet-induced adipose tissue inflammation and the development of obesity.

Am J Physiol Endocrinol Metab 2016 11 4;311(5):E881-E890. Epub 2016 Oct 4.

Division of Inflammation Research, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan.

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http://dx.doi.org/10.1152/ajpendo.00174.2016DOI Listing
November 2016

Interleukin-1 Family Cytokines in Liver Diseases.

Mediators Inflamm 2015 15;2015:630265. Epub 2015 Oct 15.

Department of Microbiology and Department of Pu-Erh Tea and Medical Science, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan.

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http://www.hindawi.com/journals/mi/2015/630265/
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http://dx.doi.org/10.1155/2015/630265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624893PMC
September 2016

Pu-erh tea extract ameliorates high-fat diet-induced nonalcoholic steatohepatitis and insulin resistance by modulating hepatic IL-6/STAT3 signaling in mice.

J Gastroenterol 2016 Aug 21;51(8):819-29. Epub 2016 Jan 21.

Key Laboratory of Pu-erh Tea Science, The Ministry of Education, Yunnan Agricultural University, Kunming, 650201, People's Republic of China.

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http://dx.doi.org/10.1007/s00535-015-1154-0DOI Listing
August 2016

Pu-erh tea extract induces the degradation of FET family proteins involved in the pathogenesis of amyotrophic lateral sclerosis.

Biomed Res Int 2014 7;2014:254680. Epub 2014 Apr 7.

Key Laboratory of Pu-Erh Tea Science, The Ministry of Education, Yunnan Agricultural University, Kunming 650201, China.

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http://dx.doi.org/10.1155/2014/254680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997874PMC
February 2015

Caspases as the key effectors of inflammatory responses against bacterial infection.

Arch Immunol Ther Exp (Warsz) 2015 Feb 18;63(1):1-13. Epub 2014 Jul 18.

Department of Microbiology, Hyogo College of Medicine, 1-1, Mukogawa-cho, Nishinomiya, Hyogo, 663-8501, Japan,

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http://dx.doi.org/10.1007/s00005-014-0301-2DOI Listing
February 2015

Inflammasome activation by mitochondrial oxidative stress in macrophages leads to the development of angiotensin II-induced aortic aneurysm.

Arterioscler Thromb Vasc Biol 2015 Jan 6;35(1):127-36. Epub 2014 Nov 6.

From the Division of Inflammation Resesarch, Center for Molecular Medicine, Jichi Medical University, Tochigi, Japan (F.U., K.S., H.K., K.T., A.K., T.K., M.T.); Department of Molecular Oncology, Shinshu University Graduate School of Medicine, Matsumoto, Japan (J.S., S.T.); Department of Surgery and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Japan (K.Y.); Cardiovascular Research Institute, Kurume University, Kurume, Japan (H.A.); Department of Microbiology, Hyogo College of Medicine, Nishinomiya, Japan (H.T.); and Department of Cell Biology, Japanese Foundation for Cancer Research, Cancer Institute, Tokyo, Japan (T.N.).

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http://dx.doi.org/10.1161/ATVBAHA.114.303763DOI Listing
January 2015

Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates inflammasomes to demolish macrophages.

Proc Natl Acad Sci U S A 2014 Oct 22;111(40):E4254-63. Epub 2014 Sep 22.

Department of Microbiology and Immunology, Division of Bacterial Infection Biology, and Nippon Institute for Biological Science, Tokyo 198-0024, Japan; and Medical Mycology Research Center, Chiba University, Chiba 260-8673, Japan

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http://dx.doi.org/10.1073/pnas.1324021111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4210038PMC
October 2014

Importance of Kupffer cells in the development of acute liver injuries in mice.

Int J Mol Sci 2014 May 5;15(5):7711-30. Epub 2014 May 5.

Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan.

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http://dx.doi.org/10.3390/ijms15057711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057701PMC
May 2014

Innate immunomodulation by lipophilic termini of lipopolysaccharide; synthesis of lipid As from Porphyromonas gingivalis and other bacteria and their immunomodulative responses.

Mol Biosyst 2013 May;9(5):987-96

Department of Chemistry, Graduate School of Science, Osaka University, Machikaneyama 1-1, Toyonaka, Osaka 560-0043, Japan.

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http://dx.doi.org/10.1039/c3mb25477aDOI Listing
May 2013

Fas-mediated inflammatory response in Listeria monocytogenes infection.

J Immunol 2013 Apr 15;190(8):4245-54. Epub 2013 Mar 15.

Department of Microbiology, Hyogo College of Medicine, Nishinomiya, 663-8501, Japan.

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http://dx.doi.org/10.4049/jimmunol.1203059DOI Listing
April 2013

Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors.

Nat Commun 2012 ;3:1034

Division of Mucosal Immunology, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, 108-8639, Japan.

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http://dx.doi.org/10.1038/ncomms2023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3658010PMC
February 2013

Lactococcus lactis subsp. cremoris FC triggers IFN-γ production from NK and T cells via IL-12 and IL-18.

Int Immunopharmacol 2012 Dec 23;14(4):729-33. Epub 2012 Oct 23.

Biomedial Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki 305-8566, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S15675769120029
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http://dx.doi.org/10.1016/j.intimp.2012.10.007DOI Listing
December 2012

Immunotherapeutic applications of IL-18.

Immunotherapy 2012 Dec;4(12):1883-94

Department of Microbiology, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya 663-8501, Japan.

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http://dx.doi.org/10.2217/imt.12.137DOI Listing
December 2012

Lactobacillus plantarum strain YU from fermented foods activates Th1 and protective immune responses.

Int Immunopharmacol 2011 Dec 3;11(12):2017-24. Epub 2011 Sep 3.

Research and Development Division, Kikkoman Corporation, Chiba, Japan.

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http://dx.doi.org/10.1016/j.intimp.2011.08.013DOI Listing
December 2011

Chemical synthesis of Helicobacter pylori lipopolysaccharide partial structures and their selective proinflammatory responses.

Chemistry 2011 Dec 16;17(51):14464-74. Epub 2011 Nov 16.

Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan.

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http://dx.doi.org/10.1002/chem.201003581DOI Listing
December 2011

Contribution of interleukin 18 to the development of infection-associated atopic dermatitis.

Curr Probl Dermatol 2011 12;41:93-103. Epub 2011 May 12.

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http://dx.doi.org/10.1159/000323302DOI Listing
September 2011

The TLR4/TRIF-Mediated Activation of NLRP3 Inflammasome Underlies Endotoxin-Induced Liver Injury in Mice.

Gastroenterol Res Pract 2010 16;2010:641865. Epub 2010 Jun 16.

Department of Microbiology, Hyogo College of Medicine, 1-1, Mukogawa-cho, Nishinomiya 663-8501, Japan.

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http://dx.doi.org/10.1155/2010/641865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904443PMC
July 2011

Essential role of B7-H1 in double-stranded RNA-induced augmentation of an asthma phenotype in mice.

Am J Respir Cell Mol Biol 2011 Jul 27;45(1):31-9. Epub 2010 Aug 27.

Department of Pulmonary Medicine, Graduate School of Medical and Dental Sciences, Kagoshima University, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.

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http://dx.doi.org/10.1165/rcmb.2009-0450OCDOI Listing
July 2011

Targeting solid tumors with non-pathogenic obligate anaerobic bacteria.

Cancer Sci 2010 Sep;101(9):1925-32

Department of Molecular Oncology, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, Tokyo, Japan.

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http://doi.wiley.com/10.1111/j.1349-7006.2010.01628.x
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http://dx.doi.org/10.1111/j.1349-7006.2010.01628.xDOI Listing
September 2010

Granzyme B is a novel interleukin-18 converting enzyme.

J Dermatol Sci 2010 Aug 17;59(2):129-35. Epub 2010 Jun 17.

Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie 514-8507, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2010.05.004DOI Listing
August 2010

Erratum to "Neutrophil-dominant psoriasis-like skin inflammation induced by epidermal-specific expression of Raf in mice" [J. Dermatol. Sci. 58 (2010) 28-35].

J Dermatol Sci 2010 Jul;59(1):64-71

Department of Dermatology, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan.

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July 2010

Importance of IL-18-induced super Th1 cells for the development of allergic inflammation.

Allergol Int 2010 Jun 24;59(2):137-41. Epub 2010 Apr 24.

Department of Immunology and Medical Zoology, Hyogo College of Medicine, Hyogo, Japan.

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http://dx.doi.org/10.2332/allergolint.10-RAI-0208DOI Listing
June 2010

Neutrophil-dominant psoriasis-like skin inflammation induced by epidermal-specific expression of Raf in mice.

J Dermatol Sci 2010 Apr 4;58(1):28-35. Epub 2010 Feb 4.

Department of Dermatology, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2010.01.004DOI Listing
April 2010

IFN-gamma is a master regulator of endotoxin shock syndrome in mice primed with heat-killed Propionibacterium acnes.

Int Immunol 2010 Mar 3;22(3):157-66. Epub 2010 Feb 3.

Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo 663-8501, Japan.

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http://dx.doi.org/10.1093/intimm/dxp122DOI Listing
March 2010

Role of ASC in the mouse model of Helicobacter pylori infection.

J Histochem Cytochem 2009 Apr 8;57(4):327-38. Epub 2008 Dec 8.

Department of Molecular Oncology, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan.

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http://dx.doi.org/10.1369/jhc.2008.952366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2664985PMC
April 2009

Freshly isolated Langerhans cells negatively regulate naïve T cell activation in response to peptide antigen through cell-to-cell contact.

J Dermatol Sci 2008 Jul 25;51(1):19-29. Epub 2008 Mar 25.

Department of Dermatology, Mie University School of Medicine, Tsu 514-8507, Japan.

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http://dx.doi.org/10.1016/j.jdermsci.2008.01.005DOI Listing
July 2008

Vaginal infection with Ureaplasma urealyticum accounts for preterm delivery via induction of inflammatory responses.

Microbiol Immunol 2008 Jun;52(6):297-304

Department of Obstetrics and Gynecology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.

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http://dx.doi.org/10.1111/j.1348-0421.2008.00039.xDOI Listing
June 2008

Interleukin-18 regulates T helper 1 or 2 immune responses of human cord blood CD4+ V alpha 24+V beta 11+ natural killer T cells.

Int J Mol Med 2007 Aug;20(2):241-5

Laboratory of Cell Transplantation, Institute for Advanced Medical Sciences, Hyogo College of Medicine, Hyogo 663-8501, Japan.

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August 2007

Role of innate immune response in liver regeneration.

J Gastroenterol Hepatol 2007 Jun;22 Suppl 1:S57-8

First Department of Surgery and Department of Immunology and Medical Zoology, Hyogo College of Medicine, Nishinomiya, Japan.

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http://dx.doi.org/10.1111/j.1440-1746.2006.04651.xDOI Listing
June 2007

Type 1 cytokine/chemokine production by mouse NK cells following activation of their TLR/MyD88-mediated pathways.

Int Immunol 2007 Mar 7;19(3):311-20. Epub 2007 Feb 7.

Department of Pediatrics, Hyogo College of Medicine, 1-1, Mukogawa-cho, Nishinomiya 663-8501, Japan.

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http://dx.doi.org/10.1093/intimm/dxl148DOI Listing
March 2007

Human mast cell chymase cleaves pro-IL-18 and generates a novel and biologically active IL-18 fragment.

J Immunol 2006 Dec;177(12):8315-9

Department of Dermatology, Mie University, Graduate School of Medicine, Tsu, Mie 514-8507, Japan.

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http://dx.doi.org/10.4049/jimmunol.177.12.8315DOI Listing
December 2006

Contribution of IL-18 to atopic-dermatitis-like skin inflammation induced by Staphylococcus aureus product in mice.

Proc Natl Acad Sci U S A 2006 Jun 24;103(23):8816-21. Epub 2006 May 24.

Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, Japan.

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http://dx.doi.org/10.1073/pnas.0602900103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1482661PMC
June 2006

Macrophage scavenger receptor down-regulates mycobacterial cord factor-induced proinflammatory cytokine production by alveolar and hepatic macrophages.

Microb Pathog 2006 Apr 6;40(4):171-6. Epub 2006 Mar 6.

Department of Host Defense, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka 545-8585, Japan.

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http://dx.doi.org/10.1016/j.micpath.2005.12.006DOI Listing
April 2006

Plasma interleukin (IL)-18 (interferon-gamma-inducing factor) and other inflammatory cytokines in patients with gouty arthritis and monosodium urate monohydrate crystal-induced secretion of IL-18.

Cytokine 2006 Jan 5;33(1):21-7. Epub 2006 Jan 5.

Division of Endocrinology and Metabolism, Department of Internal Medicine, Hyogo College of Medicine, Mukogawa-cho 1-1, Nishinomiya, Hyogo 663-8501, Japan.

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http://dx.doi.org/10.1016/j.cyto.2005.11.010DOI Listing
January 2006

Negative regulation of cytokine and TLR signalings by SOCS and others.

Adv Immunol 2005 ;87:61-122

Department of Molecular Medicine, Osaka University Graduate School of Medicine, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1016/S0065-2776(05)87003-8DOI Listing
September 2005

A novel caspase-1/toll-like receptor 4-independent pathway of cell death induced by cytosolic Shigella in infected macrophages.

J Biol Chem 2005 Apr 4;280(14):14042-50. Epub 2005 Feb 4.

Department of Microbiology and Immunology, Institute of Medical Science, University of Tokyo, 4-6-1, Shirokanedai, Minato-ku, Tokyo 108-8639, Japan.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M414671200
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http://dx.doi.org/10.1074/jbc.M414671200DOI Listing
April 2005

TNF signalings as pleiotropic gates in the liver.

Authors:
Hiroko Tsutsui

Hepatol Res 2005 Mar 12;31(3):121-3. Epub 2005 Feb 12.

Department of Immunology and Medical Zoology, Hyogo College of Medicine, Nishinomiya 663-8501, CREST, Japan Science and Technology Agency, Saitama 332-0012, Japan.

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http://dx.doi.org/10.1016/j.hepres.2004.12.005DOI Listing
March 2005

[Toll-like receptors; their signalings and biological functions].

Authors:
Hiroko Tsutsui

Arerugi 2005 Jan;54(1):1-6

Department of Immunology & Medical Zoology, Hyogo College of Medicine.

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January 2005

Induction of allergic inflammation by interleukin-18 in experimental animal models.

Immunol Rev 2004 Dec;202:115-38

Department of Immunology & Medical Zoology, Hyogo College of Medicine, Nishinomiya, Japan.

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http://dx.doi.org/10.1111/j.0105-2896.2004.00205.xDOI Listing
December 2004

ASC is essential for LPS-induced activation of procaspase-1 independently of TLR-associated signal adaptor molecules.

Genes Cells 2004 Nov;9(11):1055-67

Department of Molecular Oncology Division of Molecular and Cellular Biology Institute on Ageing and Adaptation, Shinshu University Graduate School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan.

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http://dx.doi.org/10.1111/j.1365-2443.2004.00789.xDOI Listing
November 2004

Involvement of interleukin-18 in acute graft-versus-host disease in mice.

Transplantation 2004 Nov;78(9):1245-50

Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.

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http://dx.doi.org/10.1097/01.tp.0000137934.25190.b9DOI Listing
November 2004

Adult Still's disease reflects a Th2 rather than a Th1 cytokine profile.

Clin Immunol 2004 Jul;112(1):120-5

Department of Rehabilitation, Osaka Prefecture College of Nursing, Habikino, Osaka 583-8555, Japan.

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http://dx.doi.org/10.1016/j.clim.2004.03.023DOI Listing
July 2004

Contribution of CD1d-unrestricted hepatic DX5+ NKT cells to liver injury in Plasmodium berghei-parasitized erythrocyte-injected mice.

Int Immunol 2004 Jun 13;16(6):787-98. Epub 2004 Apr 13.

Department of Immunology and Medical Zoology, Hyogo College of Medicine, Nishinomiya, Japan.

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http://dx.doi.org/10.1093/intimm/dxh080DOI Listing
June 2004

Differential upregulation of interleukin-18 receptor alpha chain between CD4+ and CD8+ T cells during acute graft-versus-host disease in mice.

J Interferon Cytokine Res 2004 May;24(5):291-6

Department of Internal Medicine, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8501, Japan.

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http://dx.doi.org/10.1089/107999004323065075DOI Listing
May 2004

Inhibition by interleukin-18 of the growth of Dunn osteosarcoma cells.

J Interferon Cytokine Res 2004 Mar;24(3):161-7

Departments of Pathology and Orthopedic Surgery, Institute for Advanced Medical Sciences, Hyogo College of Medicine, Hyogo 663-8501, Japan.

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http://dx.doi.org/10.1089/107999004322917007DOI Listing
March 2004

Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases.

Int Immunol 2004 Feb;16(2):303-14

Department of Molecular Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita City, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1093/intimm/dxh030DOI Listing
February 2004

Roles of caspase-1 in Listeria infection in mice.

Int Immunol 2004 Feb;16(2):335-43

Section of Immunobiology, Yale University School of Medicine and Howard Hughes Medical Institute, New Haven, CT 06510, USA.

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http://dx.doi.org/10.1093/intimm/dxh041DOI Listing
February 2004

Pathophysiological roles for IL-18 in inflammatory arthritis.

Expert Opin Ther Targets 2003 Dec;7(6):701-24

Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Japan.

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http://dx.doi.org/10.1517/14728222.7.6.701 DOI Listing
December 2003

Persistent secretion of IL-18 in the skin contributes to IgE response in mice.

Int Immunol 2003 May;15(5):611-21

Department of Immunology & Medical Zoology, Second Department of Surgery, Hyogo College of Medicine, Nishinomiya 663-8501, Japan.

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http://dx.doi.org/10.1093/intimm/dxg062DOI Listing
May 2003

TGFbeta down-regulates IFN-gamma production in IL-18 treated NK cell line LNK5E6.

Biochem Biophys Res Commun 2003 Jan;300(4):980-5

Department of Molecular Health Sciences, Graduate School of Pharmaceutical Sciences, Nagoya City University, Mizuho, Nagoya 467-8603, Japan.

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http://dx.doi.org/10.1016/s0006-291x(02)02939-xDOI Listing
January 2003

[IL-18 and atopic inflammation].

Tanpakushitsu Kakusan Koso 2002 Dec;47(16 Suppl):2362-8

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December 2002

A regulatory role for suppressor of cytokine signaling-1 in T(h) polarization in vivo.

Int Immunol 2002 Nov;14(11):1343-50

Department of Molecular Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita City, Osaka 565-0871, Japan.

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http://dx.doi.org/10.1093/intimm/dxf094DOI Listing
November 2002

Prevention of hepatocellular carcinoma development associated with chronic hepatitis by anti-fas ligand antibody therapy.

J Exp Med 2002 Oct;196(8):1105-11

Department of Gastroenterology, Graduate School of Medicine. Center for the Development of Molecular Target Drugs, Cancer Research Institute, Kanazawa University, Ishikawa 920-0934, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194047PMC
http://dx.doi.org/10.1084/jem.20020633DOI Listing
October 2002