Publications by authors named "Hilma Putri Lubis"

3 Publications

  • Page 1 of 1

The impact of late follicular progesterone level on in vitro fertilization-intracytoplasmic sperm injection outcome: Case-control study.

Int J Reprod Biomed 2020 May 31;18(5):367-374. Epub 2020 May 31.

Department of Biology, Faculty of Mathematics and Science, University of Indonesia, Depok, Indonesia.

Background: Studies have been conducted to improve the pregnancy rate through the in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) program. In recent years, researchers have been focusing on finding impact of high progesterone level on endometrial receptivity. However, data on whether progesterone level also affects the quality of the embryo is still limited.

Objective: The aim is to assess the effect of late follicular progesterone level on the outcome of in vitro fertilization-intracytoplasmic sperm injection (IVF-ICSI).

Materials And Methods: This was a case-control of 245 women who underwent in vitro fertilization cycle at Halim Fertility Center, Indonesia. The outcomes assessed were number of oocytes retrieved (OR), maturation rate (MR), fertilization rate (FR), number of good embryos (GE), number of fair embryos (FE), and number of poor embryos (PE). The progesterone (P4) and estradiol (E2) levels were analyzed on the day of human chorionic gonadotropin injection. Serum progesterone level was divided into three groups: 1. low progesterone ( 0.50 ng/ml), 2. normal progesterone (0.51-1.50 ng/ml), and 3. high progesterone ( 1.50 ng/ml). All outcomes were compared amongst the groups.

Results: Significant differences occurred between progesterone level on the day of human chorionic gonadotropin administration. The number of OR in group 1, 2, and 3 were 8.41 5.88 vs. 12.99 8.51 vs. 17.58 9.52, respectively.

Conclusion: Progesterone level on the day of human chorionic gonadotropin injection may have an impact on the outcome of IVF-ICSI.
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http://dx.doi.org/10.18502/ijrm.v13i5.7157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306063PMC
May 2020

Bilateral hydronephrosis and hydroureter associated with 21-22 weeks gestational age of cervical ectopic pregnancy: a case report.

Int Med Case Rep J 2019 11;12:217-222. Epub 2019 Jul 11.

Division of Reproductive, Endocrinology and Infertility, Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Sumatera Utara, Medan, Indonesia.

Cervical ectopic pregnancy is a rare form of ectopic pregnancy. This incidence represents less than 1% of all ectopic pregnancies with reported incidence rates varying from 1:1,000 to 1:95,000 pregnancies. Cervical ectopic pregnancy is difficult to diagnose. Hydronephrosis and hydroureter have never been reported as complications of cervical ectopic pregnancy, and both are diagnosed after laparotomy. The potential morbidity, highlighted in this case study, demonstrates the importance of early diagnosis of a cervical ectopic pregnancy so that early intervention and treatment can be employed.
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http://dx.doi.org/10.2147/IMCRJ.S199683DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6630720PMC
July 2019

Does oval oocyte have an impact on embryo development in in vitro fertilization?

JBRA Assist Reprod 2017 02 1;21(1):15-18. Epub 2017 Feb 1.

HFC IVF center Division of Reproductive, Endocrinology and Infertility Department of Obstetrics and Gynecology, Faculty of Medicine University of Sumatera Utara, Medan, Indonesia.

Objective: To compare the outcomes of embryo development between oval-shaped oocyte as an abnormal morphology oocyte and a normal morphology oocyte in In Vitro Fertilization (IVF).

Methods: This study was a comparative analytical study with retrospective approach which lasted from September 2014 until November 2015. For this study, we used secondary data (medical records) from 24 patients submitted to IVF at the Halim Fertility Center. The oocyte morphology was divided into two groups: normal-shaped oocyte and oval-shaped oocyte.

Results: Our study included 120 oocytes with 60 oval-shaped oocytes and 60 normal oocytes. We found fertilization rates of 68.3% in the normal oocyte group and 61.7% in the oval-shaped oocyte group; and there was no significant difference between the normal oocyte group and the oval-shaped oocyte group (p > 0.05). In the normal oocyte group, 65% had reached day 3 embryos, and in the oval-shaped oocyte group it was 50%, with no significant difference between the groups (p > 0.05). We also found 46.7% transferrable embryos in the oval oocytes group compared to 63.3% in the normal oocytes group, with no significant difference between the groups (p > 0.05).

Conclusion: There was no significant difference in fertilization rates and embryo quality between normal morphology oocytes and oval-shaped oocytes.
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http://dx.doi.org/10.5935/1518-0557.20170005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5365194PMC
February 2017
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