Hilary J Longhurst

Hilary J Longhurst

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Hilary J Longhurst

Hilary J Longhurst

Publications by authors named "Hilary J Longhurst"

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Hereditary angioedema: an update on causes, manifestations and treatment.

Br J Hosp Med (Lond) 2019 Jul;80(7):391-398

Univ.-Prof. Dr, Department of Dermatology, University Medical Center, Johannes Gutenberg University, Mainz, Germany.

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http://dx.doi.org/10.12968/hmed.2019.80.7.391DOI Listing
July 2019

Pediatricians diagnosed few patients with childhood-presented hereditary angioedema: Icatibant Outcome Survey findings.

J Allergy Clin Immunol Pract 2019 Mar 28;7(3):1078-1080. Epub 2018 Aug 28.

Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité - Universitätsmedizin Berlin, Berlin, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22132198183052
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http://dx.doi.org/10.1016/j.jaip.2018.07.047DOI Listing
March 2019

Lanadelumab for the Prophylactic Treatment of Hereditary Angioedema with C1 Inhibitor Deficiency: A Review of Preclinical and Phase I Studies.

BioDrugs 2019 Feb;33(1):33-43

Division of Rheumatology, Allergy and Immunology, University of California, San Diego, 8899 University Center Lane, Suite 230, San Diego, CA, 92122, USA.

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http://dx.doi.org/10.1007/s40259-018-0325-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373397PMC
February 2019

Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema.

N Engl J Med 2018 07;379(4):352-362

From the Division of Hematology, Oncology, and Hemostaseology, Department of Children and Adolescents, Angioedema Center, University Hospital Frankfurt (E.A.-P.), and the Fraunhofer Institute for Molecular Biology and Applied Ecology, Translational Medicine and Pharmacology (J. Graff), Frankfurt, the Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin (M. Magerl, M. Maurer), and the Department of Otorhinolaryngology and Head and Neck Surgery, Ulm University Medical Center, Ulm (J. Greve) - all in Germany; the Department of Dermatology and Allergy Center, Odense University Hospital, Odense, Denmark (A.B.); Public Health Institution University Clinic of Dermatology, School of Medicine, University Sts. Cyril and Methodius, Skopje, Macedonia (V.G.-P.); the Department of Clinical Immunology, University Hospital Zurich, Zurich, Switzerland (U.C.S.); Assistance Publique-Hôpitaux de Paris Hôpital Saint Antoine, Sorbonne Université, Paris (O.F.), and the Department of Dermatology, Université de Montpellier, Montpellier (A.D.-T.) - both in France; the Allergy and Immunology West Midlands, Birmingham Heartlands Hospital, Birmingham (A.H.), Barts Health NHS Trust-Royal London Hospital, London (H.J.L.), the National Institute for Health Research Southampton Clinical Research Facility, Southampton (W.R.), and the North Bristol NHS Trust, Southmead Hospital, Bristol (M. Gompels) - all in the United Kingdom; the Department of Dermatology, Medical University of Vienna, Vienna (T.K.), and the Department of Dermatology and Venereology, Medical University of Graz, Graz (W.A.) - both in Austria; the Hungarian Angioedema Reference Center, 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary (H.F.); the Allergology Unit, Department of Internal Medicine, Hospital Universitario Bellvitge de L'Hospitalet de Llobregat (R.L.) and Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (M. Guilarte), Barcelona, Hospital General Universitario Gregorio Marañón, Biomedical Research Network on Rare Diseases (Centro de Investigación Biomédica en Red de Enfermedades Raras)-Unit 761, Institute for Health Research, Gregorio Marañon, Madrid (M.L.B.), and Hospital Universitario Virgen del Rocío, Seville (T.G.-Q.) - all in Spain; the Division of Allergy and Clinical Immunology, University of Salerno, Salerno (M.T.), the Department of Medicine, University of Padua, Padua (M. Cancian), and Azienda Socio Sanitaria Territoriale Fatebenefratelli Sacco-Università degli Studi di Milano, Milan (A.Z., M. Cicardi) - all in Italy; the Department of Clinical Immunology and Allergy, Royal Adelaide Hospital, Adelaide, SA (W.B.S.), and Campbelltown Hospital, Immunology and Allergy, Western Sydney University, Sydney (C.K.) - both in Australia; and BioCryst Pharmaceuticals (S.D., M. Cornpropst, D.C., P.C., W.S.) and PharStat (L.F.) - both in Durham, NC.

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http://dx.doi.org/10.1056/NEJMoa1716995DOI Listing
July 2018

Cladribine treatment of multiple sclerosis is associated with depletion of memory B cells.

J Neurol 2018 May 17;265(5):1199-1209. Epub 2018 Mar 17.

Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK.

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http://dx.doi.org/10.1007/s00415-018-8830-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937883PMC
May 2018

How Not to Be Misled by Disorders Mimicking Angioedema: A Review of Pseudoangioedema.

Int Arch Allergy Immunol 2016 22;169(3):163-70. Epub 2016 Apr 22.

Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Sjaelland, Koege, Denmark.

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http://dx.doi.org/10.1159/000445835DOI Listing
February 2017

Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study.

J Allergy Clin Immunol 2017 02 16;139(2):597-606.e4. Epub 2016 Jul 16.

Department of Paediatric Immunology, Newcastle upon Tyne hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom; Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2016.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292996PMC
February 2017

Kallikrein Inhibition for Hereditary Angioedema.

N Engl J Med 2017 02;376(8):788-789

From the Barts Health NHS Trust, London.

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http://dx.doi.org/10.1056/NEJMe1611929DOI Listing
February 2017

Misdiagnosis trends in patients with hereditary angioedema from the real-world clinical setting.

Ann Allergy Asthma Immunol 2016 10;117(4):394-398

Allergy Department, Hospital La Paz Institute for Health Research, Biomedical Research Network on Rare Diseases (CIBERER, U754), Madrid, Spain.

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http://dx.doi.org/10.1016/j.anai.2016.08.014DOI Listing
October 2016

Optimizing hereditary angioedema management through tailored treatment approaches.

Expert Rev Clin Immunol 2016 23;12(1):19-31. Epub 2015 Oct 23.

a Department of Immunology, Barts Health NHS Trust , London , UK.

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http://dx.doi.org/10.1586/1744666X.2016.1100963DOI Listing
August 2016

The Icatibant Outcome Survey: treatment of laryngeal angioedema attacks.

Eur J Emerg Med 2016 Jun;23(3):224-7

aDepartment of Immunology, Barts Health NHS TrustbDepartment of Dermatology and Venereology, Medical University of Graz, Graz, AustriacInternal Medicine Department, National Reference Centre for Angioedema, Grenoble University Hospital, Grenoble, FrancedAllergy Department, Hospital La Paz Institute for Health Research (IdiPaz), Biomedical Research Network on Rare Diseases (CIBERER, U754), Madrid, SpaineDepartment of Dermatology and Allergy, Allergie-Centrum-Charité, Charité - Universitätsmedizin Berlin, Berlin, GermanyfShire, Zug, SwitzerlandgDepartment of Biomedical and Clinical Sciences, University of Milan, Luigi Sacco Hospital, Milan, Italy.

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http://dx.doi.org/10.1097/MEJ.0000000000000292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892758PMC
June 2016

Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A3, a Neutrophil-activating Eicosanoid.

J Biol Chem 2016 Jun 22;291(26):13448-64. Epub 2016 Apr 22.

From the Systems Immunity Research Institute and Division of Infection and Immunity, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom,

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http://dx.doi.org/10.1074/jbc.M115.700609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4919433PMC
June 2016

Treatment of hereditary angioedema with icatibant: efficacy in clinical trials versus effectiveness in the real-world setting.

Allergy Asthma Proc 2014 Sep-Oct;35(5):377-81. Epub 2014 Aug 6.

Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.2500/aap.2014.35.3780DOI Listing
June 2015

Secondary antibody deficiency.

Expert Rev Clin Immunol 2014 May 31;10(5):583-91. Epub 2014 Mar 31.

Immunology Department, Royal London Hospital, Barts Health NHS Trust, London, UK.

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http://dx.doi.org/10.1586/1744666X.2014.902314DOI Listing
May 2014

Acquired C1 inhibitor deficiency: should we monitor for associated antibody deficiency?

Ann Allergy Asthma Immunol 2014 Mar;112(3):265-7

Department of Immunopathology, Barts Health NHS Trust, Royal London Hospital, London, England. Electronic address:

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http://dx.doi.org/10.1016/j.anai.2013.12.024DOI Listing
March 2014

Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α.

Gut 2014 Jan 25;63(1):96-104. Epub 2012 Dec 25.

Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, , London, UK.

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http://dx.doi.org/10.1136/gutjnl-2012-303581DOI Listing
January 2014

Many faces of angioedema: focus on the diagnosis and management of abdominal manifestations of hereditary angioedema.

Eur J Gastroenterol Hepatol 2012 Apr;24(4):353-61

Department of Gastroenterology, Hepatology, and Gastrointestinal Endoscopy, Watson Clinic LLP, Lakeland, Florida 33805, USA.

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http://dx.doi.org/10.1097/MEG.0b013e3283517998DOI Listing
April 2012

Diagnosis and treatment of hereditary angio-oedema attacks.

Br J Hosp Med (Lond) 2012 Mar;73(3):148-54

Department of Immunopathology, Barts and The London NHS Trust, London E1 2ES.

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http://dx.doi.org/10.12968/hmed.2012.73.3.148DOI Listing
March 2012

New Frontiers in Subcutaneous Immunoglobulin Treatment.

Biol Ther 2011 14;1. Epub 2011 Dec 14.

CSL Behring LLC, King of Prussia, PA USA ; Case Western Reserve University, Cleveland, OH USA.

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http://dx.doi.org/10.1007/s13554-011-0009-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873072PMC
December 2011

Management of acute attacks of hereditary angioedema: potential role of icatibant.

Vasc Health Risk Manag 2010 Sep 7;6:795-802. Epub 2010 Sep 7.

Department of Immunology, Barts and The London NHS Trust, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941790PMC
http://dx.doi.org/10.2147/vhrm.s4332DOI Listing
September 2010

Secondary systemic lupus erythematosus: an analysis of 4 cases of uncontrolled hereditary angioedema.

Clin Immunol 2007 Apr 13;123(1):14-7. Epub 2006 Nov 13.

Path Links Immunology, Scunthorpe General Hospital, Scunthorpe, North Lincolnshire, UK.

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http://dx.doi.org/10.1016/j.clim.2006.09.015DOI Listing
April 2007

Hereditary angioedema: causes, manifestations and treatment.

Br J Hosp Med (Lond) 2006 Dec;67(12):654-7

Department of Immunology, Barts and The London NHS Trust, London E1 2ES.

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http://dx.doi.org/10.12968/hmed.2006.67.12.22439DOI Listing
December 2006

Sporadic case of warts, hypogammaglobulinemia, immunodeficiency, and myelokathexis syndrome.

J Allergy Clin Immunol 2005 Nov 10;116(5):1101-5. Epub 2005 Oct 10.

Department of Immunology, St Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2005.08.040DOI Listing
November 2005

Osteomyelitis complicating pyomyositis in HIV disease.

Int J STD AIDS 2004 Sep;15(9):632-4

Department of Immunology, Imperial College, Hammersmith Campus, 10th Floor, Commonwealth Building, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1258/0956462041724226DOI Listing
September 2004

Non-myeloablative bone marrow transplantation in an adult with Wiskott-Aldrich syndrome.

Br J Haematol 2002 Feb;116(2):497-9

Department of Immunopathology, St Bartholomew's Hospital, London, UK.

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http://dx.doi.org/10.1046/j.1365-2141.2002.03269.xDOI Listing
February 2002