High Seng Chai

High Seng Chai

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High Seng Chai

High Seng Chai

Publications by authors named "High Seng Chai"

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29Publications

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Late-onset Alzheimer disease risk variants mark brain regulatory loci.

Neurol Genet 2015 Aug 23;1(2):e15. Epub 2015 Jul 23.

Department of Neuroscience (M.A., M.K., M.M.C., A.K., L. Manly, J.D.B., J.S., F.Z., C.Y., C.M., T.N., L. Ma, K.M., S.L., D.W.D., S.G.Y., N.E.-T.), Department of Neurology (N.R.G.-R., N.E.-T.), and Health Sciences Research (D.S., X.W., J.C., Y.W.A.), Mayo Clinic, Jacksonville, FL; Department of Neurology (R.C.P.) and Health Sciences Research (C.W., H.S.C.), Mayo Clinic, Rochester, MN; and Department of Neurology (J.S.), Medical University of Silesia, Katowice, Poland.

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http://dx.doi.org/10.1212/NXG.0000000000000012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4807909PMC
August 2015

Elevated cardiac troponin T levels in critically ill patients with sepsis.

Am J Med 2013 Dec 28;126(12):1114-21. Epub 2013 Sep 28.

Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, Minn; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, Minn.

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http://dx.doi.org/10.1016/j.amjmed.2013.06.029DOI Listing
December 2013

Novel late-onset Alzheimer disease loci variants associate with brain gene expression.

Authors:
Mariet Allen Fanggeng Zou High Seng Chai Curtis S Younkin Julia Crook V Shane Pankratz Minerva M Carrasquillo Christopher N Rowley Asha A Nair Sumit Middha Sooraj Maharjan Thuy Nguyen Li Ma Kimberly G Malphrus Ryan Palusak Sarah Lincoln Gina Bisceglio Constantin Georgescu Debra Schultz Fariborz Rakhshan Christopher P Kolbert Jin Jen Jonathan L Haines Richard Mayeux Margaret A Pericak-Vance Lindsay A Farrer Gerard D Schellenberg Ronald C Petersen Neill R Graff-Radford Dennis W Dickson Steven G Younkin Nilüfer Ertekin-Taner Liana G Apostolova Steven E Arnold Clinton T Baldwin Robert Barber Michael M Barmada Thomas Beach Gary W Beecham Duane Beekly David A Bennett Eileen H Bigio Thomas D Bird Deborah Blacker Bradley F Boeve James D Bowen Adam Boxer James R Burke Jacqueline Buros Joseph D Buxbaum Nigel J Cairns Laura B Cantwell Chuanhai Cao Chris S Carlson Regina M Carney Steven L Carroll Helena C Chui David G Clark Jason Corneveaux Carl W Cotman Paul K Crane Carlos Cruchaga Jeffrey L Cummings Philip L De Jager Charles DeCarli Steven T DeKosky F Yesim Demirci Ramon Diaz-Arrastia Malcolm Dick Beth A Dombroski Ranjan Duara William D Ellis Denis Evans Kelley M Faber Kenneth B Fallon Martin R Farlow Steven Ferris Tatiana M Foroud Matthew Frosch Douglas R Galasko Paul J Gallins Mary Ganguli Marla Gearing Daniel H Geschwind Bernardino Ghetti John R Gilbert Sid Gilman Bruno Giordani Jonathan D Glass Alison M Goate Robert C Green John H Growdon Hakon Hakonarson Ronald L Hamilton John Hardy Lindy E Harrell Elizabeth Head Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Gregory A Jicha Lee-Way Jin Gyungah Jun M Ilyas Kamboh Jason Karlawish Anna Karydas John S K Kauwe Jeffrey A Kaye Nancy Kennedy Ronald Kim Edward H Koo Neil W Kowall Patricia Kramer Walter A Kukull James J Lah Eric B Larson Allan I Levey Andrew P Lieberman Oscar L Lopez Kathryn L Lunetta Wendy J Mack Daniel C Marson Eden R Martin Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller Thomas J Montine John C Morris Amanda J Myers Adam C Naj Petra Nowotny Joseph E Parisi Daniel P Perl Elaine Peskind Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Ruchita A Rajbhandary Murray Raskind Eric M Reiman Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Roger N Rosenberg Mary Sano Andrew J Saykin Julie A Schneider Lon S Schneider William Seeley Michael L Shelanski Michael A Slifer Charles D Smith Joshua A Sonnen Salvatore Spina Peter St George-Hyslop Robert A Stern Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Debby W Tsuang Vivianna M Van Deerlin Badri Narayan Vardarajan Harry V Vinters Jean Paul Vonsattel Li-San Wang Sandra Weintraub Kathleen A Welsh-Bohmer Jennifer Williamson Randall L Woltjer

Neurology 2012 Jul 20;79(3):221-8. Epub 2012 Jun 20.

Department of Neuroscience, Biostatistics Unit, Mayo Clinic Florida, Jacksonville, FL, USA.

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http://dx.doi.org/10.1212/WNL.0b013e3182605801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398432PMC
July 2012

Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.

Hypertension 2012 Jun 7;59(6):1204-11. Epub 2012 May 7.

Division of Nephrology and Hypertension, Department of Medicine, Mayo Clinic, College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1161/HYP.0b013e31825b30f8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530397PMC
June 2012

Batch effect correction for genome-wide methylation data with Illumina Infinium platform.

BMC Med Genomics 2011 Dec 16;4:84. Epub 2011 Dec 16.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic College of Medicine, 200 First Street, Rochester, MN 55905, USA.

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http://bmcmedgenomics.biomedcentral.com/articles/10.1186/175
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http://dx.doi.org/10.1186/1755-8794-4-84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265417PMC
December 2011

A novel bioinformatics pipeline for identification and characterization of fusion transcripts in breast cancer and normal cell lines.

Nucleic Acids Res 2011 Aug 27;39(15):e100. Epub 2011 May 27.

Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, MN, USA.

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http://dx.doi.org/10.1093/nar/gkr362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159479PMC
August 2011

Significance of elevated cardiac troponin T levels in critically ill patients with acute respiratory disease.

Am J Med 2010 Nov;123(11):1049-58

Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.amjmed.2010.06.021DOI Listing
November 2010

Copy number variation and cytidine analogue cytotoxicity: a genome-wide association approach.

BMC Genomics 2010 Jun 4;11:357. Epub 2010 Jun 4.

Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1186/1471-2164-11-357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2894803PMC
June 2010

Spatial normalization improves the quality of genotype calling for Affymetrix SNP 6.0 arrays.

BMC Bioinformatics 2010 Jun 29;11:356. Epub 2010 Jun 29.

Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1186/1471-2105-11-356DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910027PMC
June 2010

GLOSSI: a method to assess the association of genetic loci-sets with complex diseases.

BMC Bioinformatics 2009 Apr 3;10:102. Epub 2009 Apr 3.

Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, NY, USA.

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http://dx.doi.org/10.1186/1471-2105-10-102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2678095PMC
April 2009

Use of log-skew-normal distribution in analysis of continuous data with a discrete component at zero.

Stat Med 2008 Aug;27(18):3643-55

Cardiovascular Research, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1002/sim.3210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758628PMC
August 2008

Elevated cardiac troponin is an independent risk factor for short- and long-term mortality in medical intensive care unit patients.

Crit Care Med 2008 Mar;36(3):759-65

Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA.

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http://dx.doi.org/10.1097/CCM.0B013E318164E2E4DOI Listing
March 2008

Measures of arterial stiffness and wave reflection are associated with walking distance in patients with peripheral arterial disease.

Atherosclerosis 2007 Apr 26;191(2):384-90. Epub 2006 May 26.

George Washington University School of Medicine, Washington, DC, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2006.03.038DOI Listing
April 2007