Hideo Nakamura

Hideo Nakamura

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Hideo Nakamura

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A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor.

Cancer Cell 2019 Jul;36(1):51-67.e7

Arthur and Sonia Labatt Brain Tumor Research Centre, Division of Haematology/Oncology, Hospital for Sick Children, Toronto, ON M5G0A4, Canada; Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, ON M5S1A8, Canada; Division of Hematology-Oncology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Medical Biophysics, Faculty of Medicine, University of Toronto, Toronto, ON M5G1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.06.002DOI Listing
July 2019

Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors.

Acta Neuropathol Commun 2018 12 4;6(1):134. Epub 2018 Dec 4.

Division of Brain Tumor Translational Research, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.

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https://actaneurocomms.biomedcentral.com/articles/10.1186/s4
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http://dx.doi.org/10.1186/s40478-018-0630-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278135PMC
December 2018

CSF TACI and BAFF levels in patients with primary CNS lymphoma as novel diagnostic biomarkers.

Ann Clin Transl Neurol 2018 Dec 19;5(12):1611-1616. Epub 2018 Oct 19.

Department of Neurology Graduate School of Medical Sciences Kumamoto University Kumamoto Japan.

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http://dx.doi.org/10.1002/acn3.668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292192PMC
December 2018

BCL2 expression is associated with a poor prognosis independent of cellular origin in primary central nervous system diffuse large B-cell lymphoma.

J Neurooncol 2018 Oct 2;140(1):115-121. Epub 2018 Jul 2.

Department of Neurosurgery, Kumamoto University, 1-1-1 Honjo Chuo-ku, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1007/s11060-018-2940-3DOI Listing
October 2018

Effects of Surgery With Salvage Stereotactic Radiosurgery Versus Surgery With Whole-Brain Radiation Therapy in Patients With One to Four Brain Metastases (JCOG0504): A Phase III, Noninferiority, Randomized Controlled Trial.

J Clin Oncol 2018 Jun 20:JCO2018786186. Epub 2018 Jun 20.

Takamasa Kayama, Shinya Sato, Kaori Sakurada, Yukihiko Sonoda, Yamagata University Faculty of Medicine, Yamagata; Junki Mizusawa, Yoshitaka Narita, Yasuji Miyakita, Hiroshi Katayama, Haruhiko Fukuda, Soichiro Shibui, National Cancer Center Hospital; Minako Sumi, Cancer Institute Hospital; Akitake Mukasa, The University of Tokyo Graduate School of Medicine; Yoshihiro Muragaki, Motohiro Hayashi, Tokyo Women's Medical University; Takao Watanabe, Nihon University School of Medicine; Hikaru Sasaki, Keio University School of Medicine; Masao Tago, Teikyo University Mizonokuchi Hospital; Motoo Nagane, Kyorin University Faculty of Medicine, Tokyo; Ryo Nishikawa, Saitama Medical University International Medical Center, Saitama; Toshihiro Kumabe, Tohoku University Graduate School of Medicine; Eiji Shimizu, Tohoku University Hospital; Hidefumi Jokura, Furukawa Seiryo Hospital, Miyagi; Yoshiki Arakawa, Susumu Miyamoto, Takashi Mizowaki, Kyoto University Graduate School of Medicine, Kyoto; Takaaki Beppu, Iwate Medical University, Morioka; Kazuhiko Sugiyama, Hiroshima University Hospital, Hiroshima; Hirohiko Nakamura, Nakamura Memorial Hospital, Sapporo; Yoko Nakasu, Shizuoka Cancer Center, Shizuoka; Naoya Hashimoto, Osaka University Graduate School of Medicine; Manabu Kinoshita, Osaka International Cancer Institute; Akio Asai, Kansai Medical University; Koichi Iwasaki, Kitano Hospital; Tomokazu Aoki, Kitano Medical Research Institute and Hospital, Osaka; Mizuhiko Terasaki, Kurume University, Kurume; Akira Matsumura, Eiichi Ishikawa, University of Tsukuba, Tsukuba; Toshihiko Wakabayashi, Nagoya University, Nagoya; Yasuo Iwadate, Chiba University, Chiba; Shiro Ohue, Ehime University Graduate School of Medicine, Ehime; Hiroyuki Kobayashi, Hiroki Shirato, Hokkaido University Graduate School of Medicine, Hokkaido; Kenichiro Asano, Hirosaki University Graduate School of Medicine, Hirosaki City; Katsuyuki Tanaka, St Marianna University School of Medicine, Kanagawa; Hideo Nakamura, Kumamoto University, Kumamoto; Tatsuya Abe, Oita University Faculty of Medicine, Oita; Shuichi Izumoto, Hyogo College of Medicine, Hyogo; Masahiro Mizoguchi, Kyushu University, Fukuoka; Takayuki Matsuo, Nagasaki Graduate School of Biomedical Sciences, Nagasaki; and Hideo Takeshima, University of Miyazaki, Miyazaki, Japan.

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http://dx.doi.org/10.1200/JCO.2018.78.6186DOI Listing
June 2018

Improvement of visual field defects after focal resection for occipital lobe epilepsy: case report.

J Neurosurg 2018 03 19;128(3):862-866. Epub 2017 May 19.

Department of Neurosurgery, Kumamoto University Medical School, Kumamoto, Japan

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http://dx.doi.org/10.3171/2016.12.JNS161820DOI Listing
March 2018

Intertumoral Heterogeneity within Medulloblastoma Subgroups.

Authors:
Florence M G Cavalli Marc Remke Ladislav Rampasek John Peacock David J H Shih Betty Luu Livia Garzia Jonathon Torchia Carolina Nor A Sorana Morrissy Sameer Agnihotri Yuan Yao Thompson Claudia M Kuzan-Fischer Hamza Farooq Keren Isaev Craig Daniels Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Ji Yeoun Lee Wieslawa A Grajkowska Marta Perek-Polnik Alexandre Vasiljevic Cecile Faure-Conter Anne Jouvet Caterina Giannini Amulya A Nageswara Rao Kay Ka Wai Li Ho-Keung Ng Charles G Eberhart Ian F Pollack Ronald L Hamilton G Yancey Gillespie James M Olson Sarah Leary William A Weiss Boleslaw Lach Lola B Chambless Reid C Thompson Michael K Cooper Rajeev Vibhakar Peter Hauser Marie-Lise C van Veelen Johan M Kros Pim J French Young Shin Ra Toshihiro Kumabe Enrique López-Aguilar Karel Zitterbart Jaroslav Sterba Gaetano Finocchiaro Maura Massimino Erwin G Van Meir Satoru Osuka Tomoko Shofuda Almos Klekner Massimo Zollo Jeffrey R Leonard Joshua B Rubin Nada Jabado Steffen Albrecht Jaume Mora Timothy E Van Meter Shin Jung Andrew S Moore Andrew R Hallahan Jennifer A Chan Daniela P C Tirapelli Carlos G Carlotti Maryam Fouladi José Pimentel Claudia C Faria Ali G Saad Luca Massimi Linda M Liau Helen Wheeler Hideo Nakamura Samer K Elbabaa Mario Perezpeña-Diazconti Fernando Chico Ponce de León Shenandoah Robinson Michal Zapotocky Alvaro Lassaletta Annie Huang Cynthia E Hawkins Uri Tabori Eric Bouffet Ute Bartels Peter B Dirks James T Rutka Gary D Bader Jüri Reimand Anna Goldenberg Vijay Ramaswamy Michael D Taylor

Cancer Cell 2017 06;31(6):737-754.e6

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A1, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6163053PMC
June 2017

A prospective, multicentre, single-arm clinical trial of bevacizumab for patients with surgically untreatable, symptomatic brain radiation necrosis.

Neurooncol Pract 2016 Dec 7;3(4):272-280. Epub 2016 Jan 7.

Department of Neurosurgery , Osaka Medical College , Takatsuki, Osaka , Japan (M.F., N.N., T.K., S.-I.M.); Department of Neurosurgery , Kyoto University Graduate School of Medicine , Kyoto , Japan (S.M., Y.A.); Department of Neurosurgery, Chubu Medical Center for Prolonged Traumatic Brain Dysfunction , Kizawa Memorial Hospital , Minokamo , Japan (J.S., K.M.); Division of Neurological Surgery , Chiba Cancer Center , Chiba , Japan (T.I.); Proton Medical Research Center , University of Tsukuba , Tsukuba , Japan (K.T.); Department of Neurosurgery , Hokkaido University Graduate School of Medicine , Sapporo , Japan (K.H., S.T.); Department of Neurosurgery , Japanese Red Cross Medical Center , Tokyo , Japan (Y.T.); Department of Neurosurgery , Kumamoto University Graduate School of Medical Science , Kumamoto , Japan (H.N.); Department of Neurosurgery , Kyorin University Faculty of Medicine , Mitaka , Japan (M.N.); Department of Clinical Oncology and Neuro-oncology Program , Hiroshima University Hospital , Hiroshima , Japan (K.S.); Department of Neurosurgery , Kurume University School of Medicine , Kurume , Japan (M.T.); Department of Neurosurgery , Oita University Faculty of Medicine , Oita , Japan (T.A.); Department of Neurosurgery and Neuro-Oncology , National Cancer Center Hospital , Tokyo , Japan (Y.N.); Department of Neurosurgery , The University of Tokyo , Tokyo , Japan (N.S., A.M.); Department of Neurosurgery , Iwate Medical University , Morioka , Japan (K.O.); Department of Neurosurgery, Division of Hyperbaric Medicine , Iwate Medical University , Morioka , Japan (T.B.); Department of Neurosurgery , Kitasato University School of Medicine , Sagamihara , Japan (T.Kum); Department of Neurosurgery , Tokyo Medical and Dental University , Tokyo , Japan (T.N.); Department of Neurosurgery , Osaka City University Graduate School of Medicine , Osaka , Japan (N.T.); Translational Research Informatics Center , Foundation for Biomedical Research and Innovation , Kobe , Japan (E.N., S.K., Y.N.).

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http://dx.doi.org/10.1093/nop/npv064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5099992PMC
December 2016

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Authors:
Jonathon Torchia Brian Golbourn Shengrui Feng King Ching Ho Patrick Sin-Chan Alexandre Vasiljevic Joseph D Norman Paul Guilhamon Livia Garzia Natalia R Agamez Mei Lu Tiffany S Chan Daniel Picard Pasqualino de Antonellis Dong-Anh Khuong-Quang Aline C Planello Constanze Zeller Dalia Barsyte-Lovejoy Lucie Lafay-Cousin Louis Letourneau Mathieu Bourgey Man Yu Deena M A Gendoo Misko Dzamba Mark Barszczyk Tiago Medina Alexandra N Riemenschneider A Sorana Morrissy Young-Shin Ra Vijay Ramaswamy Marc Remke Christopher P Dunham Stephen Yip Ho-Keung Ng Jian-Qiang Lu Vivek Mehta Steffen Albrecht Jose Pimentel Jennifer A Chan Gino R Somers Claudia C Faria Lucia Roque Maryam Fouladi Lindsey M Hoffman Andrew S Moore Yin Wang Seung Ah Choi Jordan R Hansford Daniel Catchpoole Diane K Birks Nicholas K Foreman Doug Strother Almos Klekner Laszló Bognár Miklós Garami Péter Hauser Tibor Hortobágyi Beverly Wilson Juliette Hukin Anne-Sophie Carret Timothy E Van Meter Eugene I Hwang Amar Gajjar Shih-Hwa Chiou Hideo Nakamura Helen Toledano Iris Fried Daniel Fults Takafumi Wataya Chris Fryer David D Eisenstat Katrin Scheinemann Adam J Fleming Donna L Johnston Jean Michaud Shayna Zelcer Robert Hammond Samina Afzal David A Ramsay Nongnuch Sirachainan Suradej Hongeng Noppadol Larbcharoensub Richard G Grundy Rishi R Lulla Jason R Fangusaro Harriet Druker Ute Bartels Ronald Grant David Malkin C Jane McGlade Theodore Nicolaides Tarik Tihan Joanna Phillips Jacek Majewski Alexandre Montpetit Guillaume Bourque Gary D Bader Alyssa T Reddy G Yancey Gillespie Monika Warmuth-Metz Stefan Rutkowski Uri Tabori Mathieu Lupien Michael Brudno Ulrich Schüller Torsten Pietsch Alexander R Judkins Cynthia E Hawkins Eric Bouffet Seung-Ki Kim Peter B Dirks Michael D Taylor Anat Erdreich-Epstein Cheryl H Arrowsmith Daniel D De Carvalho James T Rutka Nada Jabado Annie Huang

Cancer Cell 2016 Dec;30(6):891-908

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Paediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Division of Hematology/Oncology, Hospital for Sick Children, Toronto, ON M5G1X8, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON M5G1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500911PMC
December 2016

Additive value of 320-section low-dose dynamic volume CT in relation to 3-T MRI for the preoperative evaluation of brain tumors.

Jpn J Radiol 2016 Oct 26;34(10):691-699. Epub 2016 Aug 26.

Departments of Diagnostic Radiology, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1007/s11604-016-0576-9DOI Listing
October 2016

[Outline of the diagnosis and examination of recurrence in metastatic brain tumor].

Nihon Rinsho 2016 09;74 Suppl 7:451-454

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September 2016

[Role of gene mutations in pathogenesis of metastatic brain tumors].

Nihon Rinsho 2016 09;74 Suppl 7:473-476

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September 2016

[Update Knowledge for Brain Tumors(8)Primary Central Nervous System Lymphoma].

Authors:
Hideo Nakamura

No Shinkei Geka 2016 Jul;44(7):605-11

Department of Neurosurgery, Kumamoto University.

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http://dx.doi.org/10.11477/mf.1436203339DOI Listing
July 2016

Adult Diffuse Astrocytoma in the Medulla Oblongata: Molecular Biological Analyses Including H3F3A Mutation of Histone H3.3.

NMC Case Rep J 2016 Apr 8;3(2):29-33. Epub 2015 Sep 8.

Department of Neurosurgery, Kumamoto University School of Medicine, Kumamoto, Kumamoto.

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http://dx.doi.org/10.2176/nmccrj.cr.2015-0012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5386147PMC
April 2016

A case of an epithelioid glioblastoma with the BRAF V600E mutation colocalized with BRAF intact low-grade diffuse astrocytoma.

Neuropathology 2016 Apr 16;36(2):181-6. Epub 2015 Sep 16.

Department of Neurosurgery, Kumamoto University, Graduate School of Medicine, Kumamoto, Japan.

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http://dx.doi.org/10.1111/neup.12258DOI Listing
April 2016

Quality of Life and Clinical Features of Long-Term Survivors Surgically Treated for Pediatric Craniopharyngioma.

World Neurosurg 2016 Jan 1;85:153-62. Epub 2015 Sep 1.

Department of Neurosurgery, Faculty of Life Sciences, Kumamoto University Graduate School, Kumamota, Japan.

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http://dx.doi.org/10.1016/j.wneu.2015.08.059DOI Listing
January 2016

Response.

J Neurosurg Pediatr 2015 Sep;16(3):350-1

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September 2015

Molecular subgroups of atypical teratoid rhabdoid tumours in children: an integrated genomic and clinicopathological analysis.

Lancet Oncol 2015 May 14;16(5):569-82. Epub 2015 Apr 14.

Division of Hematology-Oncology, University of Toronto, Toronto, ON, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Department of Pediatrics, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(15)70114-2DOI Listing
May 2015

[Brain tumor stem cells].

Nihon Rinsho 2015 May;73(5):836-43

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May 2015

Prognostic impact of completion of initial high-dose methotrexate therapy on primary central nervous system lymphoma: a single institution experience.

Int J Clin Oncol 2015 Feb 11;20(1):29-34. Epub 2014 Apr 11.

Department of Neurosurgery, Faculty of Medicine, Kumamoto University, 1-1-1 Honjo Chuo-ku, Kumamoto, 860-8556, Japan,

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http://dx.doi.org/10.1007/s10147-014-0692-4DOI Listing
February 2015

Incidence of primary central nervous system germ cell tumors in childhood: a regional survey in Kumamoto prefecture in southern Japan.

Pediatr Neurosurg 2013 16;49(3):155-8. Epub 2014 Apr 16.

Department of Neurosurgery, Kumamoto University, Kumamoto, Japan.

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http://dx.doi.org/10.1159/000358806DOI Listing
February 2015

A patient with medulloblastoma in its early developmental stage.

J Neurosurg Pediatr 2014 Dec 10;14(6):615-20. Epub 2014 Oct 10.

Departments of Neurosurgery.

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http://dx.doi.org/10.3171/2014.8.PEDS13590DOI Listing
December 2014

Clinical characteristics and pathogenesis of cerebellar glioblastoma.

Mol Med Rep 2014 Nov 9;10(5):2383-8. Epub 2014 Sep 9.

Department of Neurosurgery, Graduate School of Medical Science, Kumamoto University, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.3892/mmr.2014.2549DOI Listing
November 2014

Characteristics of brain metastases from esophageal carcinoma.

Surg Neurol Int 2014 22;5:137. Epub 2014 Sep 22.

Department of Neurosurgery, Faculty of Life Sciences, Kumamoto University School of Medicine, 1-1-1, Honjo, Kumamoto 860 - 8556, Japan.

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http://dx.doi.org/10.4103/2152-7806.141468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192927PMC
October 2014

Novel somatic and germline mutations in intracranial germ cell tumours.

Nature 2014 Jul 4;511(7508):241-5. Epub 2014 Jun 4.

1] Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas 77030, USA [2] Medical Scientist Training Program, Baylor College of Medicine, Houston, Texas 77030, USA [3] Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/nature13296DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532372PMC
July 2014

Antitumor effect of fibrin glue containing temozolomide against malignant glioma.

Cancer Sci 2014 May 19;105(5):583-91. Epub 2014 Apr 19.

Department of Neurosurgery, Kumamoto University Graduate School of Medical Science, Honjo, Chuo-ku, Kumamoto, Japan.

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http://dx.doi.org/10.1111/cas.12397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4317836PMC
May 2014

Prognostic value of isocitrate dehydrogenase 1, O6-methylguanine-DNA methyltransferase promoter methylation, and 1p19q co-deletion in Japanese malignant glioma patients.

World J Surg Oncol 2013 Oct 25;11:284. Epub 2013 Oct 25.

Department of Neurosurgery, Graduate School of Medical Science, Kumamoto University, 7-5, Inada, Obihiro, Hokkaido 080-0039, Japan.

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http://dx.doi.org/10.1186/1477-7819-11-284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3874767PMC
October 2013

Radiation-induced nitric oxide mitigates tumor hypoxia and radioresistance in a murine SCCVII tumor model.

Biochem Biophys Res Commun 2013 Aug 2;437(3):420-5. Epub 2013 Jul 2.

Laboratory of Radiation Biology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan.

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http://eprints.lib.hokudai.ac.jp/dspace/bitstream/2115/53265
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S0006291X1301091
Publisher Site
http://dx.doi.org/10.1016/j.bbrc.2013.06.093DOI Listing
August 2013

[New and future treatments for neurological disorders--knowledge essential to daily clinics and future prospects. Topics: 6. Malignant brain tumor].

Nihon Naika Gakkai Zasshi 2013 Aug;102(8):1952-7

Department of Neurosurgery, Graduate School of Life Sciences, Kumamoto University, Japan.

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http://dx.doi.org/10.2169/naika.102.1952DOI Listing
August 2013

Usefulness of immunohistochemical expression analysis of metabolic-related molecules in differentiating between intracranial neoplastic and non-neoplastic lesions.

Brain Tumor Pathol 2013 Jul 12;30(3):144-50. Epub 2012 Oct 12.

Department of Neurosurgery, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1007/s10014-012-0120-2DOI Listing
July 2013

[Computer-aided detection of metastatic brain tumors in magnetic resonance images].

Nihon Hoshasen Gijutsu Gakkai Zasshi 2013 Jun;69(6):632-40

Graduate School of Health Sciences, Kumamoto University.

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http://dx.doi.org/10.6009/jjrt.2013_jsrt_69.6.632DOI Listing
June 2013

Can MRI-derived factors predict the survival in glioblastoma patients treated with postoperative chemoradiation therapy?

Acta Radiol 2013 Mar 8;54(2):214-20. Epub 2012 Nov 8.

Department of Neurosurgery, Kumamoto University, Kumamoto, Japan.

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http://dx.doi.org/10.1258/ar.2012.120525DOI Listing
March 2013

Importance of direct macrophage-tumor cell interaction on progression of human glioma.

Cancer Sci 2012 Dec 26;103(12):2165-72. Epub 2012 Oct 26.

Department of Cell Pathology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

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http://dx.doi.org/10.1111/cas.12015DOI Listing
December 2012

Induction of autophagic cell death of glioma-initiating cells by cell-penetrating D-isomer peptides consisting of Pas and the p53 C-terminus.

Biomaterials 2012 Dec 21;33(35):9061-9. Epub 2012 Sep 21.

Department of Molecular Physiology, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1016/j.biomaterials.2012.09.003DOI Listing
December 2012

Higher incidence of epilepsy in meningiomas located on the premotor cortex: a voxel-wise statistical analysis.

Acta Neurochir (Wien) 2012 Dec 21;154(12):2241-9. Epub 2012 Oct 21.

Department of Neurosurgery, Kumamoto University Hospital, Honjo, Chuo-ku, Japan.

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http://dx.doi.org/10.1007/s00701-012-1511-1DOI Listing
December 2012

Fatty acid synthase is a predictive marker for aggressiveness in meningiomas.

J Neurooncol 2012 Sep 29;109(2):399-404. Epub 2012 Jun 29.

Department of Neurosurgery, Faculty of Medicine, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1007/s11060-012-0907-3DOI Listing
September 2012

Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Authors:
Paul A Northcott David J H Shih John Peacock Livia Garzia A Sorana Morrissy Thomas Zichner Adrian M Stütz Andrey Korshunov Jüri Reimand Steven E Schumacher Rameen Beroukhim David W Ellison Christian R Marshall Anath C Lionel Stephen Mack Adrian Dubuc Yuan Yao Vijay Ramaswamy Betty Luu Adi Rolider Florence M G Cavalli Xin Wang Marc Remke Xiaochong Wu Readman Y B Chiu Andy Chu Eric Chuah Richard D Corbett Gemma R Hoad Shaun D Jackman Yisu Li Allan Lo Karen L Mungall Ka Ming Nip Jenny Q Qian Anthony G J Raymond Nina T Thiessen Richard J Varhol Inanc Birol Richard A Moore Andrew J Mungall Robert Holt Daisuke Kawauchi Martine F Roussel Marcel Kool David T W Jones Hendrick Witt Africa Fernandez-L Anna M Kenney Robert J Wechsler-Reya Peter Dirks Tzvi Aviv Wieslawa A Grajkowska Marta Perek-Polnik Christine C Haberler Olivier Delattre Stéphanie S Reynaud François F Doz Sarah S Pernet-Fattet Byung-Kyu Cho Seung-Ki Kim Kyu-Chang Wang Wolfram Scheurlen Charles G Eberhart Michelle Fèvre-Montange Anne Jouvet Ian F Pollack Xing Fan Karin M Muraszko G Yancey Gillespie Concezio Di Rocco Luca Massimi Erna M C Michiels Nanne K Kloosterhof Pim J French Johan M Kros James M Olson Richard G Ellenbogen Karel Zitterbart Leos Kren Reid C Thompson Michael K Cooper Boleslaw Lach Roger E McLendon Darell D Bigner Adam Fontebasso Steffen Albrecht Nada Jabado Janet C Lindsey Simon Bailey Nalin Gupta William A Weiss László Bognár Almos Klekner Timothy E Van Meter Toshihiro Kumabe Teiji Tominaga Samer K Elbabaa Jeffrey R Leonard Joshua B Rubin Linda M Liau Erwin G Van Meir Maryam Fouladi Hideo Nakamura Giuseppe Cinalli Miklós Garami Peter Hauser Ali G Saad Achille Iolascon Shin Jung Carlos G Carlotti Rajeev Vibhakar Young Shin Ra Shenandoah Robinson Massimo Zollo Claudia C Faria Jennifer A Chan Michael L Levy Poul H B Sorensen Matthew Meyerson Scott L Pomeroy Yoon-Jae Cho Gary D Bader Uri Tabori Cynthia E Hawkins Eric Bouffet Stephen W Scherer James T Rutka David Malkin Steven C Clifford Steven J M Jones Jan O Korbel Stefan M Pfister Marco A Marra Michael D Taylor

Nature 2012 Aug;488(7409):49-56

Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, Ontario M5G 1L7, Canada.

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http://is.muni.cz/repo/990835/nature11327.pdf
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http://www.nature.com/doifinder/10.1038/nature11327
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http://dx.doi.org/10.1038/nature11327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683624PMC
August 2012

Ionizing radiation induces mitochondrial reactive oxygen species production accompanied by upregulation of mitochondrial electron transport chain function and mitochondrial content under control of the cell cycle checkpoint.

Free Radic Biol Med 2012 Jul 8;53(2):260-70. Epub 2012 May 8.

Laboratory of Radiation Biology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818, Japan.

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http://dx.doi.org/10.1016/j.freeradbiomed.2012.04.033DOI Listing
July 2012

Recurrence patterns of glioblastoma treated with postoperative radiation therapy: relationship between extent of resection and progression-free interval.

Jpn J Radiol 2012 Apr 20;30(3):193-7. Epub 2011 Dec 20.

Department of Medical Imaging, Faculty of Life Sciences, Kumamoto University, 4-24-1 Kuhonji, Kumamoto 862-0976, Japan.

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http://dx.doi.org/10.1007/s11604-011-0031-xDOI Listing
April 2012

Salvage treatment with temozolomide in refractory or relapsed primary central nervous system lymphoma and assessment of the MGMT status.

J Neurooncol 2012 Jan 1;106(1):155-60. Epub 2011 Jul 1.

Department of Neurosurgery, Faculty of Medicine, Kumamoto University, 1-1-1 Honjo Kumamoto, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1007/s11060-011-0652-zDOI Listing
January 2012

p53-TIGAR axis attenuates mitophagy to exacerbate cardiac damage after ischemia.

J Mol Cell Cardiol 2012 Jan 18;52(1):175-84. Epub 2011 Oct 18.

Department of Cardiovascular Medicine, Kyoto Prefectural University School of Medicine, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto 602-8566, Japan.

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http://dx.doi.org/10.1016/j.yjmcc.2011.10.008DOI Listing
January 2012

13C MR imaging of methionine-rich gliomas at 4.7T: a pilot study.

Magn Reson Med Sci 2011 ;10(2):139-42

Department of Diagnostic Radiology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

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http://dx.doi.org/10.2463/mrms.10.139DOI Listing
December 2011

Therapy-associated secondary tumors in patients with non-germinomatous malignant germ cell tumors.

J Neurooncol 2011 Nov 1;105(2):359-64. Epub 2011 May 1.

Department of Neurosurgery, Graduate School of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1007/s11060-011-0597-2DOI Listing
November 2011

Ubiquitination and downregulation of ErbB2 and estrogen receptor-alpha by kinase inhibitor MP-412 in human breast cancer cells.

J Cell Biochem 2011 Sep;112(9):2279-86

Research Division, Mitsubishi Tanabe Pharma Corporation, Yokohama, Japan.

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http://doi.wiley.com/10.1002/jcb.23147
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September 2011

Epidemiological study of primary intracranial tumors: a regional survey in Kumamoto prefecture in southern Japan--20-year study.

Int J Clin Oncol 2011 Aug 18;16(4):314-21. Epub 2011 Jan 18.

Department of Neurosurgery, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.

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http://link.springer.com/10.1007/s10147-010-0178-y
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August 2011

Essential role of the Hedgehog signaling pathway in human glioma-initiating cells.

Cancer Sci 2011 Jul 3;102(7):1306-12. Epub 2011 May 3.

Laboratory for Cell Lineage Modulation, RIKEN Center for Developmental Biology, Kobe, Japan.

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http://doi.wiley.com/10.1111/j.1349-7006.2011.01943.x
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http://dx.doi.org/10.1111/j.1349-7006.2011.01943.xDOI Listing
July 2011

Molecular and clinical analysis of glioblastoma with an oligodendroglial component (GBMO).

Brain Tumor Pathol 2011 Jul 1;28(3):185-90. Epub 2011 Jun 1.

Department of Neurosurgery, Graduate School of Life Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1007/s10014-011-0039-zDOI Listing
July 2011

Evaluation of neoadjuvant therapy in patients with nongerminomatous malignant germ cell tumors.

J Neurosurg Pediatr 2011 Apr;7(4):431-8

Department of Neurosurgery, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan.

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http://dx.doi.org/10.3171/2011.1.PEDS10433DOI Listing
April 2011

NKX2.2 suppresses self-renewal of glioma-initiating cells.

Cancer Res 2011 Feb 17;71(3):1135-45. Epub 2010 Dec 17.

Division of Molecular Genetics, Cancer and Stem Cell Research Program, Cancer Research Institute, Kanazawa University, Kanazawa, Ishikawa, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-2304DOI Listing
February 2011

Inhibition of eIF4E phosphorylation reduces cell growth and proliferation in primary central nervous system lymphoma cells.

J Neurooncol 2011 Jan 25;101(1):33-9. Epub 2010 May 25.

Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1007/s11060-010-0233-6DOI Listing
January 2011

Risk of primary childhood brain tumors related to season of birth in Kumamoto Prefecture, Japan.

Childs Nerv Syst 2011 Jan 22;27(1):75-8. Epub 2010 Jul 22.

Department of Neurosurgery, Kumamoto University Graduate School, 1-1-1 Honjo, Kumamoto, Japan.

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http://dx.doi.org/10.1007/s00381-010-1235-6DOI Listing
January 2011

p53 and TIGAR regulate cardiac myocyte energy homeostasis under hypoxic stress.

Am J Physiol Heart Circ Physiol 2010 Dec 8;299(6):H1908-16. Epub 2010 Oct 8.

Department of Cardiovascular Medicine, Kyoto Prefectural University School of Medicine, Kyoto, Japan.

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http://dx.doi.org/10.1152/ajpheart.00250.2010DOI Listing
December 2010

Ectopic adrenal cortical adenoma in the spinal region: case report and review of the literature.

Brain Tumor Pathol 2010 Oct 3;27(2):121-5. Epub 2010 Nov 3.

Department of Neurosurgery, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University Graduate School, 1-1-1 Honjo, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1007/s10014-010-0270-zDOI Listing
October 2010

Population-based epidemiological study of primary intracranial tumors in childhood.

Childs Nerv Syst 2010 Aug 27;26(8):1029-34. Epub 2010 Mar 27.

Department of Neurosurgery, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University Graduate School, 1-1-1 Honjo, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1007/s00381-010-1126-xDOI Listing
August 2010

3-Cyano-6-(5-methyl-3-pyrazoloamino)pyridines: selective Aurora A kinase inhibitors.

Bioorg Med Chem Lett 2010 Aug 25;20(15):4709-11. Epub 2010 May 25.

Medicinal Chemistry Research Laboratories, Mitsubishi Tanabe Pharma Corporation, Aoba-ku, Yokohama 227-0033, Japan.

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http://dx.doi.org/10.1016/j.bmcl.2010.04.119DOI Listing
August 2010

Induction of neurite outgrowth by alpha-phenyl-N-tert-butylnitrone through nitric oxide release and Ras-ERK pathway in PC12 cells.

Free Radic Res 2010 Jun;44(6):645-54

Laboratory of Radiation Biology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Kita-Ku, Sapporo, Hokkaido, Japan.

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http://dx.doi.org/10.3109/10715761003692537DOI Listing
June 2010

[Regeneration therapy by cell transplantation for acute coronary syndrome].

Nihon Rinsho 2010 Apr;68(4):726-30

Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine.

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April 2010

Radiation-induced glioblastoma occurring 35 years after radiation therapy for medulloblastoma: case report.

Brain Tumor Pathol 2010 Apr 28;27(1):39-43. Epub 2010 Apr 28.

Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

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http://link.springer.com/10.1007/s10014-009-0258-8
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April 2010

Body weight and serum albumin change after prosthodontic treatment among institutionalized elderly in a long-term care geriatric hospital.

Community Dent Oral Epidemiol 2009 Dec 22;37(6):534-8. Epub 2009 Sep 22.

Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan.

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http://dx.doi.org/10.1111/j.1600-0528.2009.00496.xDOI Listing
December 2009

Successful treatment of intraorbital lymphangioma with tissue fibrin glue.

Surg Neurol 2009 Dec 13;72(6):722-4; discussion 724. Epub 2009 Oct 13.

Department of Neurosurgery, Kumamoto University Medical School, Kumamoto 860-8556, Japan.

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http://dx.doi.org/10.1016/j.surneu.2009.04.013DOI Listing
December 2009

Decreased expression of germinal center-associated nuclear protein is involved in chromosomal instability in malignant gliomas.

Cancer Sci 2009 Nov 21;100(11):2069-76. Epub 2009 Jul 21.

Department of Immunology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.

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http://dx.doi.org/10.1111/j.1349-7006.2009.01293.xDOI Listing
November 2009

Successful treatment of neoadjuvant therapy for papillary tumor of the pineal region.

Brain Tumor Pathol 2009 27;26(2):73-7. Epub 2009 Oct 27.

Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-Honjo, Kumamoto, 860-8556, Japan.

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http://dx.doi.org/10.1007/s10014-009-0250-3DOI Listing
November 2009

Sox11 prevents tumorigenesis of glioma-initiating cells by inducing neuronal differentiation.

Cancer Res 2009 Oct 6;69(20):7953-9. Epub 2009 Oct 6.

Laboratory for Cell Lineage Modulation, RIKEN Center for Developmental Biology, Kobe, Japan.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-2006DOI Listing
October 2009

A 3-dimensional computed tomographic procedure for planning retrosigmoid craniotomy.

Neurosurgery 2009 May;64(5 Suppl 2):241-5; discussion 245-6

Department of Neurosurgery, Kumamoto University Medical School, Kumamoto, Japan. thamasaki-

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http://dx.doi.org/10.1227/01.NEU.0000336763.90656.2BDOI Listing
May 2009