Hideo Matsumura

Hideo Matsumura

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Hideo Matsumura

Hideo Matsumura

Publications by authors named "Hideo Matsumura"

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Properties of indirect composites polymerized with laboratory light-emitting diode units.

J Oral Sci 2019 ;61(1):178-183

Department of Fixed Prosthodontics, Nihon University School of Dentistry.

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http://dx.doi.org/10.2334/josnusd.18-0147DOI Listing
January 2019

Castability and mechanical properties of Ti-15Mo-5Zr-3Al alloy in dental casting.

J Oral Sci 2018 ;60(2):285-292

Department of Dental Materials, Nihon University School of Dentistry.

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http://dx.doi.org/10.2334/josnusd.17-0280DOI Listing
December 2018

Effect of preparation design on marginal and internal adaptation of translucent zirconia laminate veneers.

Eur J Oral Sci 2018 12 5;126(6):507-511. Epub 2018 Oct 5.

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

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http://doi.wiley.com/10.1111/eos.12574
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http://dx.doi.org/10.1111/eos.12574DOI Listing
December 2018

Use of digital impression systems with intraoral scanners for fabricating restorations and fixed dental prostheses.

J Oral Sci 2018 ;60(1):1-7

Department of Fixed Prosthodontics, Nihon University School of Dentistry.

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http://dx.doi.org/10.2334/josnusd.17-0444DOI Listing
October 2018

Effect of a silane and phosphate functional monomer on shear bond strength of a resin-based luting agent to lithium disilicate ceramic and quartz materials.

J Oral Sci 2018 Sep 25;60(3):360-366. Epub 2018 Aug 25.

Department of Fixed Prosthodontics, Nihon University School of Dentistry.

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http://dx.doi.org/10.2334/josnusd.17-0383DOI Listing
September 2018

Effect of silane compounds on bonding to fused quartz of tri-n-butylborane initiated resin.

Dent Mater J 2018 Jun 26;37(3):429-436. Epub 2018 Jan 26.

Department of Fixed Prosthodontics, Nihon University School of Dentistry.

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http://dx.doi.org/10.4012/dmj.2017-183DOI Listing
June 2018

Formation of chemical bonds on zirconia surfaces with acidic functional monomers.

J Oral Sci 2018 Jun 10;60(2):187-193. Epub 2018 May 10.

Department of Anatomy and Functional Restorations, Integrated Health Sciences, Hiroshima University Graduate School of Biomedical and Health Sciences.

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http://dx.doi.org/10.2334/josnusd.17-0160DOI Listing
June 2018

Effect of priming agents on shear bond strengths of resin-based luting agents to a translucent zirconia material.

J Prosthodont Res 2018 Apr 19;62(2):204-209. Epub 2017 Sep 19.

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jpor.2017.08.011DOI Listing
April 2018

An in vitro evaluation of fracture load of implant-supported zirconia-based prostheses fabricated with different veneer materials.

Clin Oral Implants Res 2018 Apr 27;29(4):396-403. Epub 2018 Feb 27.

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

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http://doi.wiley.com/10.1111/clr.13135
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http://dx.doi.org/10.1111/clr.13135DOI Listing
April 2018

Fracture resistance of implant-supported screw-retained zirconia-based molar restorations.

Clin Oral Implants Res 2017 Sep 13;28(9):1119-1126. Epub 2016 Jul 13.

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

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http://dx.doi.org/10.1111/clr.12926DOI Listing
September 2017

Shear bond strengths of an indirect composite layering material to a tribochemically silica-coated zirconia framework material.

Dent Mater J 2016 ;35(3):461-9

Department of Fixed Prosthodontics, Nihon University School of Dentistry.

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http://dx.doi.org/10.4012/dmj.2015-311DOI Listing
August 2017

OsHKT1;5 mediates Na exclusion in the vasculature to protect leaf blades and reproductive tissues from salt toxicity in rice.

Plant J 2017 Aug 13;91(4):657-670. Epub 2017 Jun 13.

Division of Applied Biology, Faculty of Textile Science and Technology, Shinshu University, 3-15-1, Tokida, Ueda, Nagano, 386-8567, Japan.

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http://dx.doi.org/10.1111/tpj.13595DOI Listing
August 2017

Shear bond strength of a denture base acrylic resin and gingiva-colored indirect composite material to zirconia ceramics.

J Prosthodont Res 2017 Apr 16;61(2):149-157. Epub 2016 Aug 16.

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jpor.2016.07.007DOI Listing
April 2017

Wear characteristics of polished and glazed lithium disilicate ceramics opposed to three ceramic materials.

J Oral Sci 2016 ;58(1):117-23

Department of Fixed Prosthodontics, Nihon University School of Dentistry.

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http://dx.doi.org/10.2334/josnusd.58.117DOI Listing
March 2017

Effect of a self-etching primer and phosphoric acid etching on the bond strength of 4-META/MMA-TBB resin to human enamel.

Dent Mater J 2015 24;34(2):219-26. Epub 2015 Feb 24.

Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry.

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http://dx.doi.org/10.4012/dmj.2014-227DOI Listing
January 2017

Effect of mechanochemical surface preparation on bonding to zirconia of a tri-n-butylborane initiated resin.

Dent Mater J 2017 Jan 6;36(1):19-26. Epub 2016 Dec 6.

Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry.

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http://dx.doi.org/10.4012/dmj.2016-099DOI Listing
January 2017

Development of plants resistant to by intergeneric hybridization between and .

Breed Sci 2016 Dec 29;66(5):734-741. Epub 2016 Oct 29.

Okinawa Prefectural Agricultural Research Center , 820 Makabe, Itoman, Okinawa 901-0336 , Japan.

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http://dx.doi.org/10.1270/jsbbs.16107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282761PMC
December 2016

Influence of ceramic surface texture on the wear of gold alloy and heat-pressed ceramics.

Dent Mater J 2014 ;33(6):865-73

Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry.

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October 2016

In vitro comparison of fracture load of implant-supported, zirconia-based, porcelain- and composite-layered restorations after artificial aging.

Dent Mater J 2014 ;33(5):607-13

Department of Fixed Prosthodontics, Nihon University School of Dentistry.

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September 2016

Effect of thione primers on adhesive bonding between an indirect composite material and Ag-Pd-Cu-Au alloy.

Dent Mater J 2014 ;33(5):681-8

Department of Oral Biology and Engineering, Division of Oral Health Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University.

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September 2016

Effect of silane and phosphate primers on the adhesive performance of a tri-n-butylborane initiated luting agent bonded to zirconia.

Dent Mater J 2014 4;33(2):226-32. Epub 2014 Mar 4.

Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry.

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February 2016

Effects of framework design and layering material on fracture strength of implant-supported zirconia-based molar crowns.

Clin Oral Implants Res 2015 Dec 12;26(12):1407-13. Epub 2014 Aug 12.

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

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http://doi.wiley.com/10.1111/clr.12468
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http://dx.doi.org/10.1111/clr.12468DOI Listing
December 2015

SuperSAGE as an analytical tool for host and viral gene expression.

Methods Mol Biol 2015 ;1236:181-95

Gene Research Center, Shinshu University, 3-15-1 Tokita, Ueda, Nagano, 386-8567, Japan,

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http://dx.doi.org/10.1007/978-1-4939-1743-3_14DOI Listing
June 2015

Genome sequence comparison reveals a candidate gene involved in male-hermaphrodite differentiation in papaya (Carica papaya) trees.

Mol Genet Genomics 2015 Apr 22;290(2):661-70. Epub 2014 Nov 22.

Department of Bioscience and Textile Technology, Shinshu University, Ueda, Nagano, 386-8567, Japan.

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http://dx.doi.org/10.1007/s00438-014-0955-9DOI Listing
April 2015

Fracture resistance of single-tooth implant-supported zirconia-based indirect composite-layered molar restorations.

Clin Oral Implants Res 2014 Aug 3;25(8):983-91. Epub 2013 Jun 3.

Major in Fixed Prosthodontics, Nihon University Graduate School of Dentistry, Tokyo, Japan.

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http://dx.doi.org/10.1111/clr.12199DOI Listing
August 2014

Functional characterization of a new grapevine MYB transcription factor and regulation of proanthocyanidin biosynthesis in grapes.

J Exp Bot 2014 Aug 23;65(15):4433-49. Epub 2014 May 23.

Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University, 1-4-2 Kagamiyama, Higashi-Hiroshima, Hiroshima 739-8527, Japan.

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http://dx.doi.org/10.1093/jxb/eru213DOI Listing
August 2014

Factors affecting the bond strength of denture base and reline acrylic resins to base metal materials.

J Appl Oral Sci 2013 Jul-Aug;21(4):320-6

Division of Fixed Prosthodontics, Nagasaki University Hospital, Nagasaki, Japan.

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http://dx.doi.org/10.1590/1678-775720130134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3881887PMC
January 2014

Durability of bond between an indirect composite veneering material and zirconium dioxide ceramics.

Acta Odontol Scand 2013 May-Jul;71(3-4):457-63. Epub 2012 Jul 2.

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

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http://dx.doi.org/10.3109/00016357.2012.696686DOI Listing
October 2013

MutMap-Gap: whole-genome resequencing of mutant F2 progeny bulk combined with de novo assembly of gap regions identifies the rice blast resistance gene Pii.

New Phytol 2013 Oct 24;200(1):276-83. Epub 2013 Jun 24.

Iwate Biotechnology Research Center, Kitakami, Iwate, 024-0003, Japan; United Graduate School of Iwate University, Morioka, Iwate, 020-8550, Japan.

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http://dx.doi.org/10.1111/nph.12369DOI Listing
October 2013

Current status of zirconia restoration.

J Prosthodont Res 2013 Oct 18;57(4):236-61. Epub 2013 Oct 18.

Division of Oral Biomaterials and Technology, Showa University School of Dentistry, Tokyo, Japan. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S18831958130009
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http://dx.doi.org/10.1016/j.jpor.2013.09.001DOI Listing
October 2013

The effect of different surface treatments on the bond strength of a gingiva-colored indirect composite veneering material to three implant framework materials.

Clin Oral Implants Res 2013 Sep 19;24(9):977-84. Epub 2012 Jun 19.

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

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http://dx.doi.org/10.1111/j.1600-0501.2012.02505.xDOI Listing
September 2013

Post-thermocycling shear bond strength of a gingiva-colored indirect composite layering material to three implant framework materials.

Acta Odontol Scand 2013 Sep 19;71(5):1092-100. Epub 2012 Nov 19.

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

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http://www.tandfonline.com/doi/full/10.3109/00016357.2012.74
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http://dx.doi.org/10.3109/00016357.2012.741710DOI Listing
September 2013

The influence of polymerization conditions on color stability of three indirect composite materials.

J Oral Sci 2013 Mar;55(1):51-5

Dental Technician Training School, Nihon University School of Dentistry, Tokyo, Japan.

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March 2013

Adhesive performance of silver-palladium-copper-gold alloy and component metals bonded with organic sulfur-based priming agents and a tri-n-butylborane initiated luting material.

Acta Odontol Scand 2013 Jan 9;71(1):196-204. Epub 2012 Feb 9.

Division of Applied Oral Sciences, Nihon University School of Dentistry, Chiyoda-ku, Tokyo, Japan.

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http://dx.doi.org/10.3109/00016357.2011.654260DOI Listing
January 2013

Molecular characterization of the CRa gene conferring clubroot resistance in Brassica rapa.

Plant Mol Biol 2012 Dec 4;80(6):621-9. Epub 2012 Oct 4.

Department of Bioscience and Textile Technology, Shinshu University, Ueda, Nagano 386-8567, Japan.

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http://dx.doi.org/10.1007/s11103-012-9971-5DOI Listing
December 2012

Shear bond strength between an indirect composite layering material and feldspathic porcelain-coated zirconia ceramics.

Clin Oral Investig 2012 Oct 6;16(5):1401-11. Epub 2011 Dec 6.

Department of Fixed Prosthodontics, Nihon University School of Dentistry, 1-8-13, Kanda-Surugadai, Chiyoda-Ku, Tokyo, 101-8310, Japan.

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http://dx.doi.org/10.1007/s00784-011-0641-9DOI Listing
October 2012

Surface roughness and gloss of indirect composites etched with acidulated phosphate fluoride solution.

Acta Odontol Scand 2009 ;67(5):313-20

Department of Fixed Prosthodontics, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan.

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http://dx.doi.org/10.1080/00016350903070911DOI Listing
September 2012

SuperSAGE: powerful serial analysis of gene expression.

Methods Mol Biol 2012 ;883:1-17

Gene Research Center, Shinshu University, Ueda, Nagano, Japan.

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http://dx.doi.org/10.1007/978-1-61779-839-9_1DOI Listing
September 2012

Bonding of resin-based luting cements to zirconia with and without the use of ceramic priming agents.

J Adhes Dent 2012 Aug;14(4):385-92

Department of Fized Prosthodontics, and Division of Advanced Dental Treatment, Dental Research Center Nihon University School of Dentistry, Tokyo, Japan.

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http://dx.doi.org/10.3290/j.jad.a22711DOI Listing
August 2012

Properties of indirect composites reinforced with monomer-impregnated glass fiber.

Odontology 2012 Jul 20;100(2):192-8. Epub 2011 Sep 20.

Division of General Dentistry, Nagasaki University Hospital, Nagasaki, Japan.

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http://link.springer.com/10.1007/s10266-011-0039-9
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http://dx.doi.org/10.1007/s10266-011-0039-9DOI Listing
July 2012

Adhesive bonding of Ti-6Al-7Nb alloy and component metals with acidic primers and a tri-n-butylborane initiated resin.

J Adhes Dent 2012 Jun;14(3):283-92

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

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http://dx.doi.org/10.3290/j.jad.a22712DOI Listing
June 2012

IL-6 and soluble IL-6 receptor stimulate the production of MMPs and their inhibitors via JAK-STAT and ERK-MAPK signalling in human chondrocytes.

Cell Biol Int 2012 Apr;36(4):367-76

Department of Fixed Prosthodontics and Division of Advenced Dental Treatment, Dental Research Center, Nihon University School of Dentistry, Tokyo, Japan.

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http://dx.doi.org/10.1042/CBI20110150DOI Listing
April 2012

The gene expression landscape of thermogenic skunk cabbage suggests critical roles for mitochondrial and vacuolar metabolic pathways in the regulation of thermogenesis.

Plant Cell Environ 2012 Mar 31;35(3):554-66. Epub 2011 Oct 31.

Interdisciplinary Research Organization, Faculty of Agriculture, University of Miyazaki, 1-1 Gakuenkibanadai-nishi, Miyazaki, Japan.

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http://dx.doi.org/10.1111/j.1365-3040.2011.02435.xDOI Listing
March 2012

Effect of surface treatment on bond strength between an indirect composite material and a zirconia framework.

J Oral Sci 2012 Mar;54(1):39-46

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Tokyo, Japan.

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March 2012

Hardness and microstructure of Ti-15Mo-5Zr-3Al alloy for dental casting.

Acta Odontol Scand 2011 Nov 23;69(6):328-33. Epub 2011 Mar 23.

Division of Applied Oral Sciences, Nihon University School of Dentistry, Chiyoda-ku, Tokyo, Japan.

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http://dx.doi.org/10.3109/00016357.2011.568963DOI Listing
November 2011

Influence of laboratory light sources on the wear characteristics of indirect composites.

Dent Mater J 2011 10;30(2):127-35. Epub 2011 Mar 10.

Department of Fixed Prosthodontics, Nihon University School of Dentistry, 1-8-13 Kanda-Surugadai, Chiyoda-ku, Tokyo 101-8310, Japan.

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September 2011

High-throughput SuperSAGE.

Methods Mol Biol 2011 ;687:135-46

Iwate Biotechnology Research Center, Kitakami, Iwate, Japan.

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http://dx.doi.org/10.1007/978-1-60761-944-4_9DOI Listing
February 2011

Current status of zirconia-based fixed restorations.

J Oral Sci 2010 Dec;52(4):531-9

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Chiyoda-ku, Tokyo, Japan.

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http://jos.dent.nihon-u.ac.jp/journal/52/4/531.pdf
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December 2010

Effect of acidic primers on adhesive bonding of tri-n-butylborane initiated adhesive resin to alumina.

J Oral Sci 2010 Dec;52(4):571-6

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Chiyoda-ku, Tokyo, Japan.

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December 2010

Effect of cooling rate on shear bond strength of veneering porcelain to a zirconia ceramic material.

J Oral Sci 2010 Dec;52(4):647-52

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Chiyoda-ku, Tokyo, Japan.

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December 2010

A comparison of bond strength of layered veneering porcelains to zirconia and metal.

J Prosthet Dent 2010 Oct;104(4):247-57

Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry, Tokyo, Japan.

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http://dx.doi.org/10.1016/S0022-3913(10)60133-3DOI Listing
October 2010

Evaluation of thiouracil-based adhesive systems for bonding cast silver-palladium-copper-gold alloy.

J Oral Sci 2010 Sep;52(3):405-10

Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry, Tokyo, Japan.

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September 2010

Adhesive bonding of zirconia with single-liquid acidic primers and a tri-n-butylborane initiated acrylic resin.

J Adhes Dent 2010 Aug;12(4):305-10

Nihon University Graduate School of Dentistry, Chiyoda-ku, Tokyo, Japan.

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http://dx.doi.org/10.3290/j.jad.a17549DOI Listing
August 2010

Gill transcriptome response to changes in environmental calcium in the green spotted puffer fish.

BMC Genomics 2010 Aug 17;11:476. Epub 2010 Aug 17.

Centro de Ciências do Mar, CIMAR-Laboratório Associado, University of Algarve, Campus de Gambelas, 8005-139 Faro, Portugal.

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http://dx.doi.org/10.1186/1471-2164-11-476DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091672PMC
August 2010

A nine-year clinical case study of a resin-bonded fixed partial denture seated on the maxillary anterior teeth.

J Prosthodont Res 2010 Jul 19;54(3):143-6. Epub 2010 Jan 19.

Division of General Dentistry, Nagasaki University Hospital, 1-7-1, Sakamoto, Nagasaki 852-8501, Japan.

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https://linkinghub.elsevier.com/retrieve/pii/S18831958090015
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http://dx.doi.org/10.1016/j.jpor.2009.12.005DOI Listing
July 2010

Effects of triazine dithione and hydrophobic phosphate monomers on bonding to Ag-Pd-Cu-Au alloy and titanium with a methacrylic resin-based luting agent.

J Adhes Dent 2010 Jun;12(3):215-22

Department of Fixed Prosthodontics, and Division of Advanced Dental Treatment, Dental Research Center, Nihon University School of Dentistry, Chiyoda-ku, Tokyo, Japan.

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http://jad.quintessenz.de/index.php?doc=abstract&abstrac
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http://dx.doi.org/10.3290/j.jad.a17553DOI Listing
June 2010

Bond strength of poly(methyl methacrylate) denture base material to cast titanium and cobalt-chromium alloy.

J Adhes Dent 2010 Jun;12(3):223-9

Department of Applied Prosthodontics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.

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http://dx.doi.org/10.3290/j.jad.a17550DOI Listing
June 2010

Electric response of nonspherical and spherical silica particle dispersions to ac electric field.

Langmuir 2010 Jun;26(12):10357-64

National Institute of Advanced Industrial Science & Technology, Tsukuba, Higashi1-1-1, Tsukuba, Ibaraki, 305-8565, Japan.

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http://dx.doi.org/10.1021/la100433fDOI Listing
June 2010

Effect of preliminary irradiation on depth of cure and hardness of a veneering composite.

J Oral Sci 2010 Mar;52(1):71-5

Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry, Tokyo, Japan.

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March 2010

Influence of priming agents on the short-term bond strength of an indirect composite veneering material to zirconium dioxide ceramic.

Quintessence Int 2009 Jul-Aug;40(7):545-51

Major in Fixed Prosthodontics, Nihon University Graduate School of Dentistry, Tokyo, Japan.

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January 2010

Metabolome analysis of response to oxidative stress in rice suspension cells overexpressing cell death suppressor Bax inhibitor-1.

Plant Cell Physiol 2010 Jan 16;51(1):9-20. Epub 2009 Nov 16.

Graduate School of Science and Engineering, Saitama University, Saitama, Japan.

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http://dx.doi.org/10.1093/pcp/pcp162DOI Listing
January 2010

Evaluation of single liquid primers with organic sulfur compound for bonding between indirect composite material and silver-palladium-copper-gold alloy.

Dent Mater J 2010 Jan;29(1):25-9

Division of Oral Health Sciences, Hiroshima University Graduate School of Biomedical Sciences, Minami-ku, Hiroshima, Japan.

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January 2010

Effect of preliminary irradiation on the bond strength between a veneering composite and alloy.

Dent Mater J 2010 Jan;29(1):84-8

Nihon University Graduate School of Dentistry, Chiyoda-ku, Tokyo 101-8310, Japan.

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January 2010

Shear bond strength between an indirect composite veneering material and zirconia ceramics after thermocycling.

J Oral Sci 2009 Dec;51(4):629-34

Department of Fixed Prosthodontics, Nihon University School of Dentistry, Chiyoda-ku, Tokyo, Japan.

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December 2009

Coordination of plastid protein import and nuclear gene expression by plastid-to-nucleus retrograde signaling.

Plant Physiol 2009 Nov 2;151(3):1339-53. Epub 2009 Sep 2.

The 21st Century Centers of Excellence Program, Cryobiofrontier Research Center, Iwate University, Morioka, Iwate 020-8550, Japan.

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http://dx.doi.org/10.1104/pp.109.145987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773054PMC
November 2009

Evaluation of two dual-functional primers and a tribochemical surface modification system applied to the bonding of an indirect composite resin to metals.

Odontology 2009 Jul 29;97(2):103-8. Epub 2009 Jul 29.

Department of Applied Prosthodontics, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8501, Japan.

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http://dx.doi.org/10.1007/s10266-009-0103-xDOI Listing
July 2009

Effect of alumina air-abrasion on mechanical bonding between an acrylic resin and casting alloys.

J Oral Sci 2009 Jun;51(2):161-6

Division of Applied Oral Sciences, Nihon University Graduate School of Dentistry, Tokyo, Japan.

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June 2009

Unraveling the roles of sphingolipids in plant innate immunity.

Plant Signal Behav 2009 Jun 1;4(6):536-8. Epub 2009 Jul 1.

Iwate Biotechnology Research Center, Kitakami, Iwate, Japan; Graduate School of Life Sciences, Tohoku University, Aoba, Sendai, Miyagi, Japan.

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http://dx.doi.org/10.1094/MPMI-22-1-0031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688305PMC
June 2009