Hidenori Ohnishi

Hidenori Ohnishi

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Hidenori Ohnishi

Hidenori Ohnishi

Publications by authors named "Hidenori Ohnishi"

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Generalized pustular psoriasis in pregnancy, successfully treated with certolizumab pegol.

J Dermatol 2020 Jul 4;47(7):e262-e263. Epub 2020 May 4.

Department of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan.

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http://dx.doi.org/10.1111/1346-8138.15355DOI Listing
July 2020

Myelodysplastic syndromes in a pediatric patient with Cri du Chat syndrome with a ring chromosome 5.

Int J Hematol 2020 Jun 9. Epub 2020 Jun 9.

Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.

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http://dx.doi.org/10.1007/s12185-020-02909-7DOI Listing
June 2020

Evading the AAV Immune Response in Mucopolysaccharidoses.

Int J Mol Sci 2020 May 13;21(10). Epub 2020 May 13.

Nemours/Alfred I. duPont Hospital for Children, Wilmington, DE 19803, USA.

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http://dx.doi.org/10.3390/ijms21103433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7279460PMC
May 2020

Impetigo herpetiformis with a CARD14 Thr79Ile variant successfully treated with granulocyte and monocyte adsorption apheresis.

J Dermatol 2020 Mar 23;47(3):e84-e85. Epub 2020 Jan 23.

Department of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan.

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http://dx.doi.org/10.1111/1346-8138.15241DOI Listing
March 2020

Haploinsufficiency of A20 with a novel mutation of deletion of exons 2-3 of .

Mod Rheumatol 2020 Feb 3:1-5. Epub 2020 Feb 3.

Department of Pediatrics and Child Health, Kurume University School of Medicine, Kurume, Japan.

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http://dx.doi.org/10.1080/14397595.2020.1719595DOI Listing
February 2020

Oral immunotherapy with antigenicity-modified casein induces desensitization in cow's milk allergy.

Allergy 2020 01 22;75(1):197-200. Epub 2019 Jul 22.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan.

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http://dx.doi.org/10.1111/all.13965DOI Listing
January 2020

Prominent dermal Langerhans cells in an Omenn syndrome patient with a novel mutation in the IL2RG gene.

J Dermatol 2019 Nov 27;46(11):1019-1023. Epub 2019 Aug 27.

Departments of, Dermatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.

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http://dx.doi.org/10.1111/1346-8138.15054DOI Listing
November 2019

Perampanel Inhibits Neuroblastoma Cell Proliferation Through Down-regulation of AKT and ERK Pathways.

Anticancer Res 2019 Jul;39(7):3595-3599

Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.

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http://dx.doi.org/10.21873/anticanres.13506DOI Listing
July 2019

Autosomal dominant Hashimoto's thyroiditis with a mutation in .

Clin Pediatr Endocrinol 2019 20;28(3):91-96. Epub 2019 Jul 20.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan.

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http://dx.doi.org/10.1297/cpe.28.91DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646238PMC
July 2019

Hypoallergenic casein hydrolysate for peptide-based oral immunotherapy in cow's milk allergy.

J Allergy Clin Immunol 2018 07 26;142(1):330-333. Epub 2018 Apr 26.

Research and Development Department, Bean Stalk Snow Co Ltd, Kawagoe, Japan.

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http://dx.doi.org/10.1016/j.jaci.2018.04.005DOI Listing
July 2018

IKBA S32 Mutations Underlie Ectodermal Dysplasia with Immunodeficiency and Severe Noninfectious Systemic Inflammation.

J Clin Immunol 2018 07 14;38(5):543-545. Epub 2018 Jun 14.

Department of Pediatrics and Developmental Biology, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, Japan.

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http://dx.doi.org/10.1007/s10875-018-0522-yDOI Listing
July 2018

Haploinsufficiency of A20 causes autoinflammatory and autoimmune disorders.

J Allergy Clin Immunol 2018 04 11;141(4):1485-1488.e11. Epub 2017 Dec 11.

Department of Pediatrics and Developmental Biology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.10.039DOI Listing
April 2018

Generalized Pustular Psoriasis With IL-36 Receptor Antagonist Mutation Successfully Treated With Granulocyte and Monocyte Adsorption Apheresis Accompanied by Reduced Serum IL-6 Level.

Ther Apher Dial 2018 02 15;22(1):92-93. Epub 2017 Sep 15.

Department of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan.

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http://dx.doi.org/10.1111/1744-9987.12596DOI Listing
February 2018

Heterozygous carriers of succinyl-CoA:3-oxoacid CoA transferase deficiency can develop severe ketoacidosis.

J Inherit Metab Dis 2017 11 10;40(6):845-852. Epub 2017 Jul 10.

Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu City, Gifu, 501-1194, Japan.

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http://dx.doi.org/10.1007/s10545-017-0065-zDOI Listing
November 2017

Prepubertal onset of slipped capital femoral epiphysis associated with hypothyroidism: a case report and literature review.

BMC Endocr Disord 2017 Sep 18;17(1):59. Epub 2017 Sep 18.

Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, Gifu, 501-1194, Japan.

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http://dx.doi.org/10.1186/s12902-017-0210-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604342PMC
September 2017

Immunodeficiency in Two Female Patients with Incontinentia Pigmenti with Heterozygous NEMO Mutation Diagnosed by LPS Unresponsiveness.

J Clin Immunol 2017 Aug 12;37(6):529-538. Epub 2017 Jul 12.

Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.

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http://link.springer.com/10.1007/s10875-017-0417-3
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http://dx.doi.org/10.1007/s10875-017-0417-3DOI Listing
August 2017

Nationwide survey of Baller‑Gerold syndrome in Japanese population.

Mol Med Rep 2017 May 28;15(5):3222-3224. Epub 2017 Mar 28.

Department of Clinical Research, National Hospital Organization Nagara Medical Center, Gifu 502‑8558, Japan.

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http://dx.doi.org/10.3892/mmr.2017.6408DOI Listing
May 2017

Sweet's Syndrome Successfully Treated with Granulocyte and Monocyte Adsorption Apheresis.

Case Rep Dermatol 2017 May-Aug;9(2):13-18. Epub 2017 May 22.

aDepartment of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan.

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http://dx.doi.org/10.1159/000475878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465522PMC
May 2017

Single-nucleotide substitution T to A in the polypyrimidine stretch at the splice acceptor site of intron 9 causes exon 10 skipping in the gene.

Mol Genet Genomic Med 2017 Mar 8;5(2):177-184. Epub 2017 Feb 8.

Department of PediatricsGraduate School of MedicineGifu UniversityGifuJapan; Division of Clinical GeneticsGifu University HospitalGifuJapan.

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http://dx.doi.org/10.1002/mgg3.275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5370231PMC
March 2017

Pyoderma Gangrenosum, Acne and Suppurative Hidradenitis Syndrome Treated with Granulocyte and Monocyte Adsorption Apheresis.

Acta Derm Venereol 2017 02;97(2):275-276

Department of Dermatology, Gifu University Graduate School of Medicine, 1-1 Yanagido, Gifu City 501-1194, Japan.

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http://dx.doi.org/10.2340/00015555-2507DOI Listing
February 2017

A Japanese family case with juvenile onset Behçet's disease caused by TNFAIP3 mutation.

Allergol Int 2017 Jan 19;66(1):146-148. Epub 2016 Jul 19.

Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu, Japan.

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http://dx.doi.org/10.1016/j.alit.2016.06.006DOI Listing
January 2017

T-cell epitope-containing hypoallergenic β-lactoglobulin for oral immunotherapy in milk allergy.

Pediatr Allergy Immunol 2016 12 16;27(8):818-824. Epub 2016 Sep 16.

Research and Development Department, Bean Stalk Snow Co., Ltd., Kawagoe, Japan.

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http://dx.doi.org/10.1111/pai.12642DOI Listing
December 2016

Exon 10 skipping in ACAT1 caused by a novel c.949G>A mutation located at an exonic splice enhancer site.

Mol Med Rep 2016 Nov 10;14(5):4906-4910. Epub 2016 Oct 10.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu 501‑1194, Japan.

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http://dx.doi.org/10.3892/mmr.2016.5819DOI Listing
November 2016

A case of selective IgG subclass deficiency with STAT3 mutation.

Allergol Int 2016 Oct 11;65(4):495-497. Epub 2016 Jun 11.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan.

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http://dx.doi.org/10.1016/j.alit.2016.05.004DOI Listing
October 2016

Selective Labeling of Proteins on Living Cell Membranes Using Fluorescent Nanodiamond Probes.

Nanomaterials (Basel) 2016 Mar 25;6(4). Epub 2016 Mar 25.

Department of Biophysics, Graduate School of Science, Kyoto University, Kitashirakawa-oiwake, Sakyo-ku, Kyoto 606-8502, Japan.

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http://dx.doi.org/10.3390/nano6040056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302567PMC
March 2016

Mondini dysplasia with recurrent bacterial meningitis caused by three different pathogens.

Pediatr Int 2015 Dec 5;57(6):1192-5. Epub 2015 Nov 5.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu City, Gifu, Japan.

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http://doi.wiley.com/10.1111/ped.12731
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http://dx.doi.org/10.1111/ped.12731DOI Listing
December 2015

Familial Mediterranean fever variant with repeated atypical skin eruptions.

J Dermatol 2015 Sep 11;42(9):903-5. Epub 2015 May 11.

Department of Dermatology, Gifu University Graduate School of Medicine, Gifu, Japan.

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http://dx.doi.org/10.1111/1346-8138.12929DOI Listing
September 2015

Merkel cell polyomavirus-positive Merkel cell carcinoma in a patient with epidermodysplasia verruciformis.

Acta Derm Venereol 2015 Jan;95(1):98-9

Department of Dermatology, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.

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http://dx.doi.org/10.2340/00015555-1868DOI Listing
January 2015

The structural basis for receptor recognition of human interleukin-18.

Nat Commun 2014 Dec 15;5:5340. Epub 2014 Dec 15.

1] Department of Pediatrics, Graduate School of Medicine, Gifu University, Yanagido 1-1, Gifu 501-1194, Japan [2] Biomedical Informatics, Medical Information Sciences Division, The United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University, Gifu 501-1194, Japan.

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http://dx.doi.org/10.1038/ncomms6340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4275594PMC
December 2014

Purification, crystallization and preliminary X-ray crystallographic analysis of human IL-18 and its extracellular complexes.

Acta Crystallogr F Struct Biol Commun 2014 Oct 25;70(Pt 10):1351-6. Epub 2014 Sep 25.

Department of Molecular Engineering, Graduate School of Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510, Japan.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4188078PMC
http://dx.doi.org/10.1107/S2053230X14016926DOI Listing
October 2014

A complement factor B mutation in a large kindred with atypical hemolytic uremic syndrome.

J Clin Immunol 2014 Aug 8;34(6):691-5. Epub 2014 Jun 8.

Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan,

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http://dx.doi.org/10.1007/s10875-014-0058-8DOI Listing
August 2014

Functional assessment of the mutational effects of human IRAK4 and MyD88 genes.

Mol Immunol 2014 Mar 5;58(1):66-76. Epub 2013 Dec 5.

Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan; Heisei College of Health Sciences, 180 Kurono, Gifu 501-1131, Japan.

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http://dx.doi.org/10.1016/j.molimm.2013.11.008DOI Listing
March 2014

Hyporesponsiveness to the infecting serotype after vaccination of children with seven-valent pneumococcal conjugate vaccine following invasive pneumococcal disease.

Vaccine 2014 Mar 29;32(13):1444-50. Epub 2014 Jan 29.

Laboratory for Clinical Research on Infectious Disease, International Research Center for Infectious Diseases, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan; Infectious Disease Surveillance Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjyuku, Tokyo 162-8640, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2014.01.031DOI Listing
March 2014

Pediatric allergy and immunology in Japan.

Pediatr Allergy Immunol 2013 Nov 16;24(7):704-14. Epub 2013 Sep 16.

Department of Allergy, Clinical Research Center for Allergy and Rheumatology, National Hospital Organization, Sagamihara National Hospital, Sagamihara, Kanagawa, Japan.

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http://doi.wiley.com/10.1111/pai.12117
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http://dx.doi.org/10.1111/pai.12117DOI Listing
November 2013

In vitro analysis of the functional effects of an NLRP3 G809S variant with the co-existence of MEFV haplotype variants in atypical autoinflammatory syndrome.

J Clin Immunol 2013 Feb 27;33(2):325-34. Epub 2012 Sep 27.

Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.

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http://dx.doi.org/10.1007/s10875-012-9805-xDOI Listing
February 2013

The role of dendritic cells in the generation of CD4(+) CD25(HI) Foxp3(+) T cells induced by amino acid copolymers.

Int Immunol 2013 Jan 11;25(1):53-65. Epub 2012 Sep 11.

Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA 02138, USA.

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https://academic.oup.com/intimm/article-lookup/doi/10.1093/i
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http://dx.doi.org/10.1093/intimm/dxs087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3619970PMC
January 2013

Propranolol as an alternative treatment option for pediatric lymphatic malformation.

Tohoku J Exp Med 2013 01;229(1):61-6

Department of Pediatrics, Gifu University Graduate School of Medicine, Gifu University, Gifu City, Japan.

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http://dx.doi.org/10.1620/tjem.229.61DOI Listing
January 2013

Autosomal-dominant chronic mucocutaneous candidiasis with STAT1-mutation can be complicated with chronic active hepatitis and hypothyroidism.

J Clin Immunol 2012 Dec 31;32(6):1213-20. Epub 2012 Jul 31.

Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.

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http://dx.doi.org/10.1007/s10875-012-9744-6DOI Listing
December 2012

[To get a cure for childfood asthma -a new strategy -therapy on two wheels-].

Arerugi 2012 Dec;61(12):1736-43

Gifu University Graduate School of Medicine.

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December 2012

Molecular analysis of the binding mode of Toll/interleukin-1 receptor (TIR) domain proteins during TLR2 signaling.

Mol Immunol 2012 Oct 4;52(3-4):108-16. Epub 2012 Jun 4.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Yanagido 1-1, Gifu 501-1194, Japan.

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http://dx.doi.org/10.1016/j.molimm.2012.05.003DOI Listing
October 2012

Characterization of NLRP3 variants in Japanese cryopyrin-associated periodic syndrome patients.

J Clin Immunol 2012 Apr 24;32(2):221-9. Epub 2011 Dec 24.

Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu 501-1194, Japan.

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http://dx.doi.org/10.1007/s10875-011-9629-0DOI Listing
April 2012

Structural property of soybean protein P34 and specific IgE response to recombinant P34 in patients with soybean allergy.

Int J Mol Med 2012 Feb 16;29(2):153-8. Epub 2011 Nov 16.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan.

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http://dx.doi.org/10.3892/ijmm.2011.841DOI Listing
February 2012

Genetic variations in MyD88 adaptor-like are associated with atopic dermatitis.

Int J Mol Med 2011 Jun 8;27(6):795-801. Epub 2011 Mar 8.

Department of Pediatrics, Graduate School of Medicine, Gifu University, 1-1 Yanagido, Gifu, Japan.

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http://dx.doi.org/10.3892/ijmm.2011.645DOI Listing
June 2011

Mutation in the Q28SDD31SD site, but not in the two SQ sites of the survival of motor neuron protein, affects its foci formation.

Int J Mol Med 2010 Nov;26(5):667-71

Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu 501-1194, Japan.

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http://dx.doi.org/10.3892/ijmm_00000512DOI Listing
November 2010

1H, 13C, and 15N resonance assignment of the TIR domain of human MyD88.

Biomol NMR Assign 2010 Oct 31;4(2):123-5. Epub 2010 Mar 31.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Yanagido 1-1, Gifu, 501-1194, Japan.

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http://dx.doi.org/10.1007/s12104-010-9222-0DOI Listing
October 2010

[Diagnostic approach for the autoinflammatory syndromes based on the molecular mechanism of innate immunity].

Arerugi 2009 Nov;58(11):1502-12

Department of Pediatrics, Graduate School of Medicine, Gifu University.

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November 2009

Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling.

Proc Natl Acad Sci U S A 2009 Jun 8;106(25):10260-5. Epub 2009 Jun 8.

Department of Pediatrics, Graduate School of Medicine, Center for Emerging Infectious Diseases, and Center for Advanced Drug Research, Gifu University, Gifu, Japan.

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http://dx.doi.org/10.1073/pnas.0812956106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693180PMC
June 2009

[Primary immunodeficiency diseases caused by defects in innate immunity: update].

Arerugi 2009 Jan;58(1):19-28

Department of Pediatrics, Gifu University.

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January 2009

Hypothermia augments NF-kappaB activity and the production of IL-12 and IFN-gamma.

Allergol Int 2008 Dec 1;57(4):331-8. Epub 2008 Sep 1.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan.

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http://dx.doi.org/10.2332/allergolint.O-08-532DOI Listing
December 2008

Expression, purification and structural analysis of human IL-18 binding protein: a potent therapeutic molecule for allergy.

Allergol Int 2008 Dec 1;57(4):367-76. Epub 2008 Dec 1.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu, Japan.

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http://dx.doi.org/10.2332/allergolint.O-08-546DOI Listing
December 2008

A novel polymorphism, E254K, in the 5-lipoxygenase gene associated with bronchial asthma.

Int J Mol Med 2008 Feb;21(2):139-44

Department of Pediatrics, Graduate School of Medicine, Gifu University, Gifu 501-1193, Japan.

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February 2008

Systematic optimization of active protein expression using GFP as a folding reporter.

Protein Expr Purif 2004 Aug;36(2):327-32

Department of Pediatrics, Graduate School of Medicine, Gifu University, Yanagido 1-1, Gifu, Gifu 501-1194, Japan.

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http://dx.doi.org/10.1016/j.pep.2004.04.023DOI Listing
August 2004

Generation of highly stable IL-18 based on a ligand-receptor complex structure.

Biochem Biophys Res Commun 2004 Apr;317(1):181-6

Department of Pediatrics, Gifu University School of Medicine, Tsukasa 40, Gifu 500-8705, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2004.03.024DOI Listing
April 2004

The structure and binding mode of interleukin-18.

Nat Struct Biol 2003 Nov 5;10(11):966-71. Epub 2003 Oct 5.

Department of Pediatrics, Gifu University School of Medicine, Tsukasa 40, Gifu 500-8705, Japan.

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http://dx.doi.org/10.1038/nsb993DOI Listing
November 2003

Optimized gene synthesis and high expression of human interleukin-18.

Protein Expr Purif 2003 Nov;32(1):110-8

Department of Pediatrics, Gifu University School of Medicine, Tsukasa 40, Gifu 500-8705, Japan.

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http://dx.doi.org/10.1016/j.pep.2003.08.003DOI Listing
November 2003