Publications by authors named "Hidenori Ochi"

100Publications

Predicting atrial fibrillation using a combination of genetic risk score and clinical risk factors.

Heart Rhythm 2020 May 11;17(5 Pt A):699-705. Epub 2020 Jan 11.

Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.

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May 2020

Endoplasmic reticulum-mediated induction of interleukin-8 occurs by hepatitis B virus infection and contributes to suppression of interferon responsiveness in human hepatocytes.

Virology 2018 12 18;525:48-61. Epub 2018 Sep 18.

Department of Gastroenterology and Metabolism, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan; Liver Research Project Center, Hiroshima University, Hiroshima, Japan; Laboratory for Digestive Diseases, RIKEN Center for Integrative Medical Sciences, Hiroshima, Japan. Electronic address:

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December 2018

Gene Polymorphisms Are Associated With Occurrence of Tachycardia-Induced Cardiomyopathy in Patients With Atrial Fibrillation.

Circ Genom Precis Med 2018 07;11(7):e001980

Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan (Y.N., A.S., Y.O., T.T., C.M., H.M., S.T., M.A., N.H., S.O., Y.K.).

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July 2018

Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice.

Biochem Biophys Res Commun 2018 06 13;500(2):152-157. Epub 2018 Apr 13.

Department of Gastroenterology and Metabolism, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Research Center for Hepatology and Gastroenterology, Hiroshima University, Hiroshima, Japan; Laboratory for Digestive Diseases, RIKEN Center for Integrative Medical Sciences, Hiroshima, Japan. Electronic address:

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June 2018

Serial profiling of circulating tumor DNA for optimization of anti-VEGF chemotherapy in metastatic colorectal cancer patients.

Int J Cancer 2018 04 29;142(7):1418-1426. Epub 2017 Nov 29.

Department of Gastroenterology and Metabolism, Institute of Biomedical and Health Sciences, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

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April 2018

Involvement of Porphyromonas gingivalis in the progression of non-alcoholic fatty liver disease.

J Gastroenterol 2018 Feb 24;53(2):269-280. Epub 2017 Jul 24.

Department of Gastroenterology and Metabolism, Division of Frontier Medical Science, Programs for Biomedical Research Graduate School of Biomedical Science, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

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February 2018

Three patients treated with sofosbuvir plus ledipasvir for recurrent hepatitis C after liver transplantation.

Clin J Gastroenterol 2017 Apr 21;10(2):179-184. Epub 2017 Feb 21.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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April 2017

Antiviral effects of anti-HBs immunoglobulin and vaccine on HBs antigen seroclearance for chronic hepatitis B infection.

J Gastroenterol 2016 Nov 4;51(11):1073-1080. Epub 2016 Mar 4.

Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Science, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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November 2016

Safety and efficacy of dual therapy with daclatasvir and asunaprevir for older patients with chronic hepatitis C.

J Gastroenterol 2017 Apr 8;52(4):504-511. Epub 2016 Sep 8.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551, Japan.

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April 2017

Total hip arthroplasty using a Kerboull-type plate for rapidly destructive coxarthrosis: comparison with uncemented acetabular component.

Eur J Orthop Surg Traumatol 2016 Feb 11;26(2):189-94. Epub 2016 Jan 11.

Department of Orthopedic Surgery, Juntendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo, Japan.

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February 2016

Common Variant Near HEY2 Has a Protective Effect on Ventricular Fibrillation Occurrence in Brugada Syndrome by Regulating the Repolarization Current.

Circ Arrhythm Electrophysiol 2016 Jan;9(1):e003436

From the Department of Cardiovascular Medicine, Hiroshima University Graduate School of Biomedical & Health Sciences, Hiroshima, Japan (A.S., C.M., H.I., H.K., H.M., K.S., M.T., Noboru Oda, Nozomu Oda, S. Tomomori, S.K., T.T., Y. O., Y.K., Y.N., Y.W.); Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan (D.M., H.O., K.C., Y.N.); Division of Frontier Medical Science, Department of Gastroenterology and Metabolism, Programs for Biomedical Research Graduate School of Biomedical Science (H.O., K.C., Y.H.), and Department of Cellular Biology, Research Institute for Radiation Biology and Medicine (S. Tashiro), Hiroshima University, Hiroshima, Japan; and Division of Cardiology, Nagoya Daini Red Cross Hospital, Nagoya, Japan (Y.Y.).

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January 2016

Combination therapies with daclatasvir and asunaprevir on NS3-D168 mutated HCV in human hepatocyte chimeric mice.

Antivir Ther 2016 12;21(4):307-15. Epub 2015 Nov 12.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.

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January 2018

Effect of tenofovir disoproxil fumarate on drug-resistant HBV clones.

J Infect 2016 Jan 26;72(1):91-102. Epub 2015 Oct 26.

Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Liver Research Project Center, Hiroshima University, Hiroshima, Japan; Laboratory for Digestive Diseases, Center for Genomic Medicine, The Institute of Physical and Chemical Research (RIKEN), Hiroshima, Japan. Electronic address:

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January 2016

Three patients treated with daclatasvir and asunaprevir for recurrent hepatitis C after liver transplantation: Case report.

Hepatol Res 2016 Jun 2;46(7):707-12. Epub 2015 Nov 2.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

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June 2016

Rapid, Sensitive, and Accurate Evaluation of Drug Resistant Mutant (NS5A-Y93H) Strain Frequency in Genotype 1b HCV by Invader Assay.

PLoS One 2015 17;10(6):e0130022. Epub 2015 Jun 17.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan; Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan; Liver Research Project Center, Hiroshima University, Hiroshima, Japan.

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April 2016

Circulating Tumor DNA Analysis for Liver Cancers and Its Usefulness as a Liquid Biopsy.

Cell Mol Gastroenterol Hepatol 2015 Sep 17;1(5):516-534. Epub 2015 Jun 17.

Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Science, Hiroshima University, Hiroshima, Japan; Liver Research Project Center, Hiroshima University, Hiroshima, Japan; Laboratory for Digestive Diseases, RIKEN Center for Integrative Medical Sciences, Hiroshima, Japan.

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September 2015

Long term persistence of NS5A inhibitor-resistant hepatitis C virus in patients who failed daclatasvir and asunaprevir therapy.

J Med Virol 2015 Nov 16;87(11):1913-20. Epub 2015 Jun 16.

Department of Gastroenterology and Metabolism, Applied Life Science, Institute of Biomedical and Health Science, Hiroshima University, Hiroshima, Japan.

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November 2015

Association between variants in the interferon lambda 4 locus and substitutions in the hepatitis C virus non-structural protein 5A.

J Hepatol 2015 Sep 4;63(3):554-63. Epub 2015 Apr 4.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan; Liver Research Project Center, Hiroshima University, Hiroshima, Japan; Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan. Electronic address:

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September 2015

Differences in serum microRNA profiles in hepatitis B and C virus infection.

J Infect 2015 Mar 5;70(3):273-87. Epub 2014 Nov 5.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan; Laboratory for Digestive Diseases, Center for Genomic Medicine, RIKEN, Hiroshima, Japan; Liver Research Project Center, Hiroshima University, Hiroshima, Japan. Electronic address:

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March 2015

HLA-DQB1*03 confers susceptibility to chronic hepatitis C in Japanese: a genome-wide association study.

PLoS One 2013 20;8(12):e84226. Epub 2013 Dec 20.

Laboratory for Digestive Diseases, Center for Integrative Medical Sciences, RIKEN, Hiroshima, Japan ; Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan ; Liver Research Project Center, Hiroshima University, Hiroshima, Japan.

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October 2014

A novel TK-NOG based humanized mouse model for the study of HBV and HCV infections.

Biochem Biophys Res Commun 2013 Nov 16;441(1):230-5. Epub 2013 Oct 16.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Science, Hiroshima University, Hiroshima, Japan; Liver Research Project Center, Hiroshima University, Hiroshima, Japan.

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November 2013

[Recent progress in the study of genetic variants associated with liver diseases].

Nihon Shokakibyo Gakkai Zasshi 2013 Sep;110(9):1577-90

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University.

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September 2013

A translational study of resistance emergence using sequential direct-acting antiviral agents for hepatitis C using ultra-deep sequencing.

Am J Gastroenterol 2013 Sep 30;108(9):1464-72. Epub 2013 Jul 30.

Center for Medical Specialist Graduate Education and Research, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

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September 2013

Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients.

J Gastroenterol 2013 Oct 9;48(10):1188-204. Epub 2013 Feb 9.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.

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October 2013

Hepatitis B virus-specific miRNAs and Argonaute2 play a role in the viral life cycle.

PLoS One 2012 16;7(10):e47490. Epub 2012 Oct 16.

Department of Gastroenterology and Metabolism, Applied Life Sciences, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.

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March 2013

Involvement of microRNA-224 in cell proliferation, migration, invasion, and anti-apoptosis in hepatocellular carcinoma.

J Gastroenterol Hepatol 2013 Mar;28(3):565-75

Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima City, Hiroshima, Japan.

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March 2013

Identification of novel HCV deletion mutants in chronic hepatitis C patients.

Antivir Ther 2012 25;17(8):1551-61. Epub 2012 Jul 25.

Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Japan.

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June 2013

IL28B polymorphism is associated with fatty change in the liver of chronic hepatitis C patients.

J Gastroenterol 2012 Jul 18;47(7):834-44. Epub 2012 Feb 18.

Programs for Biomedical Research, Division of Frontier Medical Science, Department of Gastroenterology and Metabolism, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.

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July 2012

Hepatocellular carcinoma: towards personalized medicine.

Cancer Sci 2012 May 15;103(5):846-50. Epub 2012 Mar 15.

Laboratory for Digestive Diseases, RIKEN Center for Genomic Medicine, Hiroshima, Japan.

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May 2012

Severe necroinflammatory reaction caused by natural killer cell-mediated Fas/Fas ligand interaction and dendritic cells in human hepatocyte chimeric mouse.

Hepatology 2012 Aug 10;56(2):555-66. Epub 2012 Jul 10.

Department of Medicine and Molecular Science, Division of Frontier Medical Science, Programs for Biomedical Research, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.

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August 2012