Publications










Effects of K-877, a novel selective PPARα modulator (SPPARMα), in dyslipidaemic patients: A randomized, double blind, active- and placebo-controlled, phase 2 trial.
Atherosclerosis 2016 Jun 26;249:36-43. Epub 2016 Feb 26.
Laboratory for Systems Biology and Medicine (LSBM), Research Center for Advanced Science and Technology (RCAST), The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo, 153-8904, Japan. Electronic address:



Differential association of frailty with cognitive decline and sarcopenia in community-dwelling older adults.
J Am Med Dir Assoc 2015 Feb 20;16(2):120-4. Epub 2014 Sep 20.
Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan.


AMAP1 as a negative-feedback regulator of nuclear factor-κB under inflammatory conditions.
Sci Rep 2014 May 28;4:5094. Epub 2014 May 28.
1] Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan [2] Department of Clinical Innovative Medicine, Institute for Advancement of Clinical and Translational Science, Kyoto University Hospital, Kyoto, Japan.





Chronic kidney disease (CKD) is an independent risk factor for long-term care insurance (LTCI) need certification among older Japanese adults: a two-year prospective cohort study.
Arch Gerontol Geriatr 2013 Nov-Dec;57(3):328-32. Epub 2013 Apr 6.
Department of Human Health Sciences, Kyoto University Graduate School of Medicine, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto 606-8507, Japan.

Priorities of health care outcomes for the elderly.
J Am Med Dir Assoc 2013 Jul 14;14(7):479-84. Epub 2013 Feb 14.
Department of Geriatric Medicine, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.

Multicenter study to determine the diagnosis criteria of heterozygous familial hypercholesterolemia in Japan.
J Atheroscler Thromb 2012 25;19(11):1019-26. Epub 2012 Oct 25.
Department of Molecular Innovation in Lipidology, National Cerebral and Cardiovascular Center Research Institute, Osaka, Japan.

Both conventional indices of cognitive function and frailty predict levels of care required in a long-term care insurance program for memory clinic patients in Japan.
Geriatr Gerontol Int 2012 Oct 2;12(4):630-6. Epub 2012 Feb 2.
Departments of Geriatric Medicine, Graduate School of Medicine, Kyoto University, Faculty of Social Studies, Doshisha University, Kyoto, Japan.


Background to discuss guidelines for control of plasma HDL-cholesterol in Japan.
J Atheroscler Thromb 2012 12;19(3):207-12. Epub 2012 Jan 12.
Food and Nutritional Sciences, College of Bioscience and Biotechnology, Chubu University, Kasugai, Japan.

Diagnosis and management of type I and type V hyperlipoproteinemia.
J Atheroscler Thromb 2012 1;19(1):1-12. Epub 2011 Dec 1.
Department of Clinical and Molecular Epidemiology, 22nd Century Medical and Research Center, University of Tokyo Hospital, Bunkyo-ku, Tokyo, Japan.


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