Hidekazu Hiroaki

Hidekazu Hiroaki

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Hidekazu Hiroaki

Publications by authors named "Hidekazu Hiroaki"

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Using H amide temperature coefficients to define intrinsically disordered regions: An alternative NMR method.

Protein Sci 2018 10 3;27(10):1821-1830. Epub 2018 Oct 3.

Laboratory of Structural Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya, 464-8601, Japan.

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http://dx.doi.org/10.1002/pro.3485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199157PMC
October 2018

Discovery of Potent Disheveled/Dvl Inhibitors Using Virtual Screening Optimized With NMR-Based Docking Performance Index.

Front Pharmacol 2018 5;9:983. Epub 2018 Sep 5.

Laboratory of Structural Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya, Japan.

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https://www.frontiersin.org/article/10.3389/fphar.2018.00983
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http://dx.doi.org/10.3389/fphar.2018.00983DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134994PMC
September 2018

Common molecular pathogenesis of disease-related intrinsically disordered proteins revealed by NMR analysis.

J Biochem 2018 Jan;163(1):11-18

Laboratory of Structural and Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya University, Aichi 464-8601, Japan.

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http://dx.doi.org/10.1093/jb/mvx056DOI Listing
January 2018

Discovery of Cryoprotective Activity in Human Genome-Derived Intrinsically Disordered Proteins.

Int J Mol Sci 2018 Jan 30;19(2). Epub 2018 Jan 30.

Laboratory of Structural Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8601, Japan.

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http://www.mdpi.com/1422-0067/19/2/401
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http://dx.doi.org/10.3390/ijms19020401DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855623PMC
January 2018

Ecl1 is a zinc-binding protein involved in the zinc-limitation-dependent extension of chronological life span in fission yeast.

Mol Genet Genomics 2017 Apr 3;292(2):475-481. Epub 2017 Feb 3.

Laboratory of Molecular Microbiology, Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Chikusa-ku, Nagoya, 464-8601, Japan.

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http://dx.doi.org/10.1007/s00438-016-1285-xDOI Listing
April 2017

Nuclear magnetic resonance evidence for the dimer formation of beta amyloid peptide 1-42 in 1,1,1,3,3,3-hexafluoro-2-propanol.

Anal Biochem 2016 Apr 7;498:59-67. Epub 2016 Jan 7.

Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya 464-8601, Japan; Graduate School of Science, Nagoya University, Nagoya 464-8601, Japan. Electronic address:

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http://dx.doi.org/10.1016/j.ab.2015.12.021DOI Listing
April 2016

Na, K-ATPase α3 is a death target of Alzheimer patient amyloid-β assembly.

Proc Natl Acad Sci U S A 2015 Aug 29;112(32):E4465-74. Epub 2015 Jul 29.

Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation (FBRI), Kobe 650-0047, Japan; Mitsubishi Kagaku Institute of Life Sciences (MITILS; dissolved in March 2010); Department of Anatomy and Developmental Biology, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan;

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http://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/
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http://www.pnas.org/lookup/doi/10.1073/pnas.1421182112
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http://dx.doi.org/10.1073/pnas.1421182112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538662PMC
August 2015

A Method for Systematic Assessment of Intrinsically Disordered Protein Regions by NMR.

Int J Mol Sci 2015 Jul 10;16(7):15743-60. Epub 2015 Jul 10.

Division of Structural Biology, Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8601, Japan.

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http://dx.doi.org/10.3390/ijms160715743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519922PMC
July 2015

Crystal structure of afadin PDZ domain-nectin-3 complex shows the structural plasticity of the ligand-binding site.

Protein Sci 2015 Mar 13;24(3):376-85. Epub 2015 Jan 13.

Division of Structural Biology, Graduate School of Medicine, Kobe University, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan; Research Center for Structural and Functional Proteomics, Institute for Protein Research, Osaka University, 3-2 Yamadaoka, Suita, 565-0871, Japan; Global-COE (Center of Excellence) Program for Integrative Membrane Biology, Kobe University, 7-5-1 Kusunoki-cho, Chuo, Kobe, Hyogo, 650-0017, Japan.

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http://dx.doi.org/10.1002/pro.2628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4353363PMC
March 2015

An optimized N-based method for the expression and purification of intrinsically disordered proteins for an NMR study.

Intrinsically Disord Proteins 2015 23;3(1):e1011004. Epub 2015 Feb 23.

Laboratory of Structural Molecular Pharmacology; Graduate School of Pharmaceutical Sciences; Nagoya University; Furocho, Chikusa-ku, Nagoya, Japan; The Structural Biology Research Center and Division of Biological Science; Graduate School of Science; Nagoya University; Furocho, Nagoya, Japan.

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http://dx.doi.org/10.1080/21690707.2015.1011004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5314886PMC
February 2015

Multiple interactions of the intrinsically disordered region between the helicase and nuclease domains of the archaeal Hef protein.

J Biol Chem 2014 Aug 19;289(31):21627-39. Epub 2014 Jun 19.

From the Department of Bioscience and Biotechnology, Graduate School of Bioresource and Bioenvironmental Sciences, and Faculty of Agriculture, Kyushu University, Fukuoka 812-8581,

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http://dx.doi.org/10.1074/jbc.M114.554998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118122PMC
August 2014

Decreased amyloidogenicity caused by mutational modulation of surface properties of the immunoglobulin light chain BRE variable domain.

Biochemistry 2014 Aug 4;53(31):5162-73. Epub 2014 Aug 4.

Division of Structural Biology, Department of Biochemistry and Molecular Biology, Graduate School of Medicine, Kobe University , 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.

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http://dx.doi.org/10.1021/bi5007892DOI Listing
August 2014

IDEAL in 2014 illustrates interaction networks composed of intrinsically disordered proteins and their binding partners.

Nucleic Acids Res 2014 Jan 30;42(Database issue):D320-5. Epub 2013 Oct 30.

Faculty of Engineering, Maebashi Institute of Technology, Maebashi 371-0816, Japan, Graduate School of Information Science, Nagoya University, Nagoya 464-8601, Japan, HOLONICS Corporation, Numazu 411-0803, Japan and Graduate School of Pharmaceutical Sciences, Nagoya University, Nagoya 464-8601, Japan.

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http://dx.doi.org/10.1093/nar/gkt1010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965115PMC
January 2014

Accidental interaction between PDZ domains and diclofenac revealed by NMR-assisted virtual screening.

Molecules 2013 Aug 9;18(8):9567-81. Epub 2013 Aug 9.

Laboratory of Structural Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya University, Furocho, Chikusa-ku, Nagoya 464-8601, Japan.

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http://dx.doi.org/10.3390/molecules18089567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270271PMC
August 2013

[NMR methods for observing protein-ligand interaction].

Authors:
Hidekazu Hiroaki

Seikagaku 2013 Aug;85(8):679-86

Laboratory of Structural and Molecular Pharmacology, Division of Structural Biology, Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya-City 464-8601, Japan.

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August 2013

MIT domain of Vps4 is a Ca2+-dependent phosphoinositide-binding domain.

J Biochem 2013 May 19;153(5):473-81. Epub 2013 Feb 19.

Laboratory of Structural and Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8601, Japan.

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http://dx.doi.org/10.1093/jb/mvt012DOI Listing
May 2013

Recent applications of isotopic labeling for protein NMR in drug discovery.

Authors:
Hidekazu Hiroaki

Expert Opin Drug Discov 2013 May 12;8(5):523-36. Epub 2013 Mar 12.

Nagoya University, Graduate School of Pharmaceutical Sciences, Furocho, Chikusa-kum, Koto-kenkyu-kan, Nagoya, 464-8601, Japan.

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http://dx.doi.org/10.1517/17460441.2013.779665DOI Listing
May 2013

An assignment of intrinsically disordered regions of proteins based on NMR structures.

J Struct Biol 2013 Jan 7;181(1):29-36. Epub 2012 Nov 7.

Graduate School of Information Sciences, Nagoya University, Nagoya 464-8601, Japan.

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http://dx.doi.org/10.1016/j.jsb.2012.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529935PMC
January 2013

¹H, ¹³C, and ¹⁵N resonance assignment of the SPFH domain of human stomatin.

Biomol NMR Assign 2012 Apr 5;6(1):23-5. Epub 2011 Jun 5.

Division of Structural Biology, Graduate School of Medicine, Kobe University, 7-5-1, Kusunoki-cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan.

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http://dx.doi.org/10.1007/s12104-011-9317-2DOI Listing
April 2012

Effect of Ca2+ on the microtubule-severing enzyme p60-katanin. Insight into the substrate-dependent activation mechanism.

FEBS J 2012 Apr 5;279(7):1339-52. Epub 2012 Mar 5.

Department of Molecular Engineering, Graduate School of Engineering, Kyoto University, Kyoto, Japan.

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http://dx.doi.org/10.1111/j.1742-4658.2012.08528.xDOI Listing
April 2012

IDEAL: Intrinsically Disordered proteins with Extensive Annotations and Literature.

Nucleic Acids Res 2012 Jan 8;40(Database issue):D507-11. Epub 2011 Nov 8.

Faculty of Engineering, Maebashi Institute of Technology, Maebashi, Gunma 371-0816, Japan.

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http://dx.doi.org/10.1093/nar/gkr884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245138PMC
January 2012

1H, 13C, and 15N resonance assignment of the first PDZ domain of mouse ZO-1.

Biomol NMR Assign 2011 Oct 24;5(2):207-10. Epub 2011 Mar 24.

Division of Structural Biology Graduate School of Medicine, Kobe University, Kobe, Hyogo, Japan.

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http://dx.doi.org/10.1007/s12104-011-9301-xDOI Listing
October 2011

A simplified recipe for assigning amide NMR signals using combinatorial 14N amino acid inverse-labeling.

J Struct Funct Genomics 2011 Sep 25;12(3):167-74. Epub 2011 Aug 25.

Division of Structural Biology, Kobe University Graduate School of Medicine, 7-5-1, Kusunoki-cho, Chuo, Kobe, 650-0017, Japan.

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http://dx.doi.org/10.1007/s10969-011-9116-0DOI Listing
September 2011

Structure and function of the N-terminal nucleolin binding domain of nuclear valosin-containing protein-like 2 (NVL2) harboring a nucleolar localization signal.

J Biol Chem 2011 Jun 7;286(24):21732-41. Epub 2011 Apr 7.

Division of Structural Biology, Graduate School of Medicine, Kobe University, 7-5-1 Kusunokicho, Chuo-ku, Kobe, Hyogo 650-0017, Japan.

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http://dx.doi.org/10.1074/jbc.M110.174680DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3122229PMC
June 2011

Structural difference of vasoactive intestinal peptide in two distinct membrane-mimicking environments.

Biochim Biophys Acta 2011 May 23;1814(5):724-30. Epub 2011 Mar 23.

Graduate School of Medicine, Kobe University, Chuo-ku, Kobe, Hyogo, Japan.

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http://dx.doi.org/10.1016/j.bbapap.2011.03.009DOI Listing
May 2011

SH3YL1 regulates dorsal ruffle formation by a novel phosphoinositide-binding domain.

J Cell Biol 2011 May;193(5):901-16

Division of Membrane Biology, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Hyogo 650-0017, Japan.

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http://dx.doi.org/10.1083/jcb.201012161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105542PMC
May 2011

SAHG, a comprehensive database of predicted structures of all human proteins.

Nucleic Acids Res 2011 Jan 3;39(Database issue):D487-93. Epub 2010 Nov 3.

Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology, Tokyo 135-0064, Japan.

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http://dx.doi.org/10.1093/nar/gkq1057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013665PMC
January 2011

1H, 13C, and 15N resonance assignment of the TIR domain of human MyD88.

Biomol NMR Assign 2010 Oct 31;4(2):123-5. Epub 2010 Mar 31.

Department of Pediatrics, Graduate School of Medicine, Gifu University, Yanagido 1-1, Gifu, 501-1194, Japan.

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http://dx.doi.org/10.1007/s12104-010-9222-0DOI Listing
October 2010

Crystal structure of a PFU-PUL domain pair of Saccharomyces cerevisiae Doa1/Ufd3.

Kobe J Med Sci 2010 Oct 21;56(3):E125-39. Epub 2010 Oct 21.

Division of Molecular Pharmacology and Pharmacogenomics, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe, Japan.

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October 2010

A common substrate recognition mode conserved between katanin p60 and VPS4 governs microtubule severing and membrane skeleton reorganization.

J Biol Chem 2010 May 25;285(22):16822-9. Epub 2010 Mar 25.

Department of Molecular Engineering, Graduate School of Engineering, Kyoto University, Kyoto-Daigaku Katsura, Nishikyo-ku, Kyoto 615-8530, Japan.

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http://dx.doi.org/10.1074/jbc.M110.108365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878028PMC
May 2010

Unusual thermal disassembly of the SPFH domain oligomer from Pyrococcus horikoshii.

Biophys J 2009 Oct;97(7):2034-43

Field of Supramolecular Biology, International Graduate School of Arts and Sciences, Yokohama City University, Kanagawa, Japan.

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http://dx.doi.org/10.1016/j.bpj.2009.07.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756375PMC
October 2009

Structural basis for the multiple interactions of the MyD88 TIR domain in TLR4 signaling.

Proc Natl Acad Sci U S A 2009 Jun 8;106(25):10260-5. Epub 2009 Jun 8.

Department of Pediatrics, Graduate School of Medicine, Center for Emerging Infectious Diseases, and Center for Advanced Drug Research, Gifu University, Gifu, Japan.

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http://dx.doi.org/10.1073/pnas.0812956106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2693180PMC
June 2009

High-resolution multi-dimensional NMR spectroscopy of proteins in human cells.

Nature 2009 Mar;458(7234):106-9

Department of Molecular Engineering, Graduate School of Engineering, Kyoto University, Nishikyo-Ku, Kyoto 615-8510, Japan.

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http://www.nature.com/articles/nature07839
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http://dx.doi.org/10.1038/nature07839DOI Listing
March 2009

The solution structure of the C-terminal domain of NfeD reveals a novel membrane-anchored OB-fold.

Protein Sci 2008 Nov 7;17(11):1915-24. Epub 2008 Aug 7.

Field of Supramolecular Biology, International Graduate School of Arts and Sciences, Yokohama City University, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.

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http://doi.wiley.com/10.1110/ps.034736.108
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http://dx.doi.org/10.1110/ps.034736.108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2578811PMC
November 2008

[Molecular mechanism for the ligand recognition by the extracellular domain of class B GPCR].

Seikagaku 2008 Oct;80(10):948-58

Division of Structural Biology, Graduate School of Medicine, Kobe University, 7-5-1 Suehiro-cho, Chuo-ku, Kobe, Hyogo 650-0017, Japan.

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October 2008

Intracellular protein delivery activity of peptides derived from insulin-like growth factor binding proteins 3 and 5.

Exp Cell Res 2008 Aug 29;314(13):2352-61. Epub 2008 May 29.

Division of Biophysics, International Graduate School of Arts and Sciences, Yokohama City University, 1-7-29 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1016/j.yexcr.2008.05.008DOI Listing
August 2008

Kinetic and thermodynamic evidence for flipping of a methyl-CpG binding domain on methylated DNA.

Biochemistry 2008 Mar 12;47(10):3266-71. Epub 2008 Feb 12.

Department of Molecular Engineering, Graduate School of Engineering, Kyoto University, Katsura, Kyoto 615-8510, Japan.

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http://dx.doi.org/10.1021/bi7019029DOI Listing
March 2008

[Recent progress on structural biology of GPCR: perspectives and limits].

Tanpakushitsu Kakusan Koso 2008 Mar;53(3):256-64

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March 2008

Fluoroscopic assessment of protein leakage during Xenopus oocytes in-cell NMR experiment by co-injected EGFP.

Anal Biochem 2007 Dec 10;371(2):247-9. Epub 2007 Aug 10.

Division of Biophysics, Graduate School of Integrated Sciences, Yokohama City University, Yokohama 230-0045, Japan.

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http://dx.doi.org/10.1016/j.ab.2007.08.006DOI Listing
December 2007

LBT/PTD dual tagged vector for purification, cellular protein delivery and visualization in living cells.

Biochim Biophys Acta 2007 Feb 6;1773(2):141-6. Epub 2006 Dec 6.

Division of Molecular Biophysics, International Graduate School of Arts and Sciences, Yokohama City University, 1-7-29 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1016/j.bbamcr.2006.11.016DOI Listing
February 2007

Fine-tuning of protein domain boundary by minimizing potential coiled coil regions.

J Biomol NMR 2007 Jan 16;37(1):53-63. Epub 2006 Dec 16.

Field of Supramolecular Biology, International Graduate School of Arts and Sciences, Yokohama City University, 1-7-29 Tsurumi, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1007/s10858-006-9103-0DOI Listing
January 2007

The common phospholipid-binding activity of the N-terminal domains of PEX1 and VCP/p97.

FEBS J 2006 Nov 3;273(21):4959-71. Epub 2006 Oct 3.

International Graduate School of Arts and Sciences, Yokohama City University, 1-7-29 Suehiro-cho, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1111/j.1742-4658.2006.05494.xDOI Listing
November 2006

In-cell NMR spectroscopy of proteins inside Xenopus laevis oocytes.

J Biomol NMR 2006 Nov 20;36(3):179-88. Epub 2006 Sep 20.

International Graduate School of Arts and Sciences, Yokohama City University, Yokohama, 230-0045, Japan.

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http://dx.doi.org/10.1007/s10858-006-9079-9DOI Listing
November 2006

Crystal structure of SUMO-3-modified thymine-DNA glycosylase.

J Mol Biol 2006 May 31;359(1):137-47. Epub 2006 Mar 31.

Graduate School of Integrated Science, Yokohama City University, Japan.

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http://dx.doi.org/10.1016/j.jmb.2006.03.036DOI Listing
May 2006

High thermal stability imparted by a designed tandem Arg-Trp stretch in an alpha-helical coiled coil.

Angew Chem Int Ed Engl 2005 Sep;44(38):6180-3

Department of Material Sciences, Graduate School of Engineering, Nagoya Institute of Technology, Gokiso-chou, Nagoya 466-8555, Japan.

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http://dx.doi.org/10.1002/anie.200500806DOI Listing
September 2005

Structural characterization of the MIT domain from human Vps4b.

Biochem Biophys Res Commun 2005 Aug;334(2):460-5

International Graduate School of Arts and Sciences, Yokohama City University, Yokohama, Kanagawa 230 0045, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2005.06.110DOI Listing
August 2005

Crystal structure of thymine DNA glycosylase conjugated to SUMO-1.

Nature 2005 Jun;435(7044):979-82

Graduate School of Integrated Science, Yokohama City University, Yokohama 230-0045, Japan.

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http://dx.doi.org/10.1038/nature03634DOI Listing
June 2005

Structure of the UBA domain of Dsk2p in complex with ubiquitin molecular determinants for ubiquitin recognition.

Structure 2005 Apr;13(4):521-32

Graduate School of Integrated Science, Yokohama City University, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1016/j.str.2005.01.011DOI Listing
April 2005

[High-throughput construction of expression vector for protein domain analysis].

Tanpakushitsu Kakusan Koso 2004 Dec;49(16):2587-94

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December 2004

Structure of the N-terminal domain of PEX1 AAA-ATPase. Characterization of a putative adaptor-binding domain.

J Biol Chem 2004 Nov 24;279(48):50060-8. Epub 2004 Aug 24.

Graduate School of Integrated Science, Yokohama City University, 1-7-29 Suehiro, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M407837200
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http://dx.doi.org/10.1074/jbc.M407837200DOI Listing
November 2004

Crystallographic characterization of the N-terminal domain of PEX1.

Acta Crystallogr D Biol Crystallogr 2004 Nov 20;60(Pt 11):2098-9. Epub 2004 Oct 20.

Graduate School of Integrated Science, Yokohama City University, 1-7-29 Suehiro, Tsurumi-ku, Yokohama, Kanagawa 230-0045, Japan.

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http://scripts.iucr.org/cgi-bin/paper?S090744490402428X
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http://dx.doi.org/10.1107/S090744490402428XDOI Listing
November 2004

Two-metal ion, Ni(II) and Cu(II), binding alpha-helical coiled coil peptide.

J Am Chem Soc 2004 Nov;126(43):14023-8

Graduate School of Material Science, Nagoya Institute of Technology, Gokiso-cho, Nagoya 466-8555, Japan.

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http://dx.doi.org/10.1021/ja047945rDOI Listing
November 2004

High-throughput construction method for expression vector of peptides for NMR study suited for isotopic labeling.

Protein Eng Des Sel 2004 Apr 27;17(4):305-14. Epub 2004 May 27.

Graduate School of Integrated Science, Yokohama City University, 1-7-29 Suehirocho, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1093/protein/gzh044DOI Listing
April 2004

The PRESAT-vector: asymmetric T-vector for high-throughput screening of soluble protein domains for structural proteomics.

Protein Sci 2004 Mar;13(3):652-8

Graduate School of Integrated Science, Yokohama City University, 1-7-29 Suehirocho, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1110/ps.03439004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2286733PMC
March 2004

Structure of the ubiquitin-interacting motif of S5a bound to the ubiquitin-like domain of HR23B.

J Biol Chem 2004 Feb 29;279(6):4760-7. Epub 2003 Oct 29.

Graduate School of Integrated Science, Yokohama City University, 1-7-29 Suehiro, Tsurumi, Yokohama, Kanagawa 230-0045, Japan.

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http://dx.doi.org/10.1074/jbc.M309448200DOI Listing
February 2004

Thermodynamic study of hybridization properties of heterochiral nucleic acids.

Biochem Biophys Res Commun 2003 Sep;309(1):79-83

Osaka University of Pharmaceutical Sciences, 4-20-1 Nasahara, Takatsuki, Osaka, Japan.

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http://dx.doi.org/10.1016/s0006-291x(03)01531-6DOI Listing
September 2003

Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation.

Proc Natl Acad Sci U S A 2003 Apr 2;100(8):4474-9. Epub 2003 Apr 2.

Medical Institute of Bioregulation, Kyushu University, and Department of Molecular and Structural Biology, Kyushu University Graduate School of Medicine, Fukuoka 812-8582, Japan.

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http://dx.doi.org/10.1073/pnas.0735712100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153580PMC
April 2003