Hicham Drissi

Hicham Drissi

UNVERIFIED PROFILE

Are you Hicham Drissi?   Register this Author

Register author
Hicham Drissi

Hicham Drissi

Publications by authors named "Hicham Drissi"

Are you Hicham Drissi?   Register this Author

100Publications

1158Reads

24Profile Views

Advances and Promises of Nutritional Influences on Natural Bone Repair.

J Orthop Res 2020 Apr 26;38(4):695-707. Epub 2019 Nov 26.

Department of Orthopaedics, School of Medicine, Emory University, Atlanta, Georgia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jor.24527DOI Listing
April 2020

Deletion of Wnt5a in osteoclasts results in bone loss through decreased bone formation.

Ann N Y Acad Sci 2020 Mar 9;1463(1):45-59. Epub 2020 Jan 9.

Department of Orthopaedics, Emory University School of Medicine, Atlanta, Georgia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/nyas.14293DOI Listing
March 2020

Deletion of Runx1 in osteoclasts impairs murine fracture healing through progressive woven bone loss and delayed cartilage remodeling.

J Orthop Res 2019 Nov 26. Epub 2019 Nov 26.

Department of Orthopaedics, School of Medicine, Emory University, Atlanta, Georgia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jor.24537DOI Listing
November 2019

Articular cartilage protection in Ctsk mice is associated with cellular and molecular changes in subchondral bone and cartilage matrix.

J Cell Physiol 2018 11 21;233(11):8666-8676. Epub 2018 May 21.

Department of Orthopaedics, Emory University, Atlanta, Georgia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.26745DOI Listing
November 2018

Transcriptional Mechanisms of Secondary Fracture Healing.

Curr Osteoporos Rep 2018 04;16(2):146-154

Department of Orthopaedics, School of Medicine, Emory University, Atlanta, GA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11914-018-0429-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6262839PMC
April 2018

A novel role for cathepsin K in periosteal osteoclast precursors during fracture repair.

Ann N Y Acad Sci 2018 03 26;1415(1):57-68. Epub 2018 Feb 26.

Department of Orthopaedics, Emory University School of Medicine, Atlanta, Georgia.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/nyas.13629
Publisher Site
http://dx.doi.org/10.1111/nyas.13629DOI Listing
March 2018

Dried plum alleviates symptoms of inflammatory arthritis in TNF transgenic mice.

J Nutr Biochem 2018 02 16;52:54-61. Epub 2017 Oct 16.

Department of Orthpaedic Surgery, Columbia University, 650 W. 168th Street, Black Building 14-1410, New York, NY 10032, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jnutbio.2017.10.002DOI Listing
February 2018

Calreticulin inhibits inflammation-induced osteoclastogenesis and bone resorption.

J Orthop Res 2017 12 18;35(12):2658-2666. Epub 2017 Jul 18.

Department of Orthopaedic Surgery and Rehabilitation, Center for Musculoskeletal Care, Yale University School of Medicine, 47 College Street, New Haven, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jor.23587DOI Listing
December 2017

Overexpression of MiR-335-5p Promotes Bone Formation and Regeneration in Mice.

J Bone Miner Res 2017 Dec 28;32(12):2466-2475. Epub 2017 Aug 28.

Division of Oral Biology, Tufts University School of Dental Medicine, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbmr.3230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732062PMC
December 2017

Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation.

Bone 2017 02 22;95:124-135. Epub 2016 Nov 22.

Department of Orthopaedic Surgery, United States; Department of Genetics and Genome Sciences, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2016.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819877PMC
February 2017

Shear deformations of human articular cartilage: Certain mechanical anisotropies apparent at large but not small shear strains.

J Mech Behav Biomed Mater 2017 01 11;65:53-65. Epub 2016 Aug 11.

University of Connecticut, Department of Mechanical Engineering, Storrs, CT, USA; University of Connecticut, Department of Biomedical Engineering, Storrs, CT, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmbbm.2016.08.012DOI Listing
January 2017

Cyclic loading of human articular cartilage: The transition from compaction to fatigue.

J Mech Behav Biomed Mater 2017 01 1;65:734-742. Epub 2016 Oct 1.

Departments of Biomedical and Mechanical Engineering, University of Connecticut, Storrs, CT, United States. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmbbm.2016.09.040DOI Listing
January 2017

Regeneration of Articular Cartilage by Human ESC-Derived Mesenchymal Progenitors Treated Sequentially with BMP-2 and Wnt5a.

Stem Cells Transl Med 2017 01 5;6(1):40-50. Epub 2016 Aug 5.

Department of Orthopaedic Surgery, UConn Musculoskeletal Institute, UConn Stem Cell Institute, UConn Health, University of Connecticut, Farmington, Connecticut, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.5966/sctm.2016-0020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5442752PMC
January 2017

The Multifaceted Osteoclast; Far and Beyond Bone Resorption.

J Cell Biochem 2016 08 26;117(8):1753-6. Epub 2016 Apr 26.

University of Connecticut Health Center, Orthopaedics Surgery, 263 Farmington Ave, Farmington 06034, Connecticut.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jcb.25560
Publisher Site
http://dx.doi.org/10.1002/jcb.25560DOI Listing
August 2016

Runx1 Regulates Myeloid Precursor Differentiation Into Osteoclasts Without Affecting Differentiation Into Antigen Presenting or Phagocytic Cells in Both Males and Females.

Endocrinology 2016 08 6;157(8):3058-69. Epub 2016 Jun 6.

Departments of Orthopaedic Surgery (D.N.P., X.Y., H.D., J.L.), Medicine (J.K., S.J., J.L.), and Genetics and Genome Sciences (H.D.), University of Connecticut Health, Farmington, Connecticut 06030.

View Article

Download full-text PDF

Source
https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
Publisher Site
http://dx.doi.org/10.1210/en.2015-2037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967120PMC
August 2016

HIF-1-Dependent IL-6 Activation in Articular Chondrocytes Initiating Synovitis in Femoral Head Ischemic Osteonecrosis.

J Bone Joint Surg Am 2016 Jul;98(13):1122-31

Center for Excellence in Hip Disorders, Texas Scottish Rite Hospital for Children, Dallas, Texas Department of Orthopaedic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas

View Article

Download full-text PDF

Source
http://jbjs.org/content/98/13/1122.full.pdf
Web Search
http://jbjs.org/cgi/doi/10.2106/JBJS.15.01209
Publisher Site
http://dx.doi.org/10.2106/JBJS.15.01209DOI Listing
July 2016

Biodistribution of LV-TSTA transduced rat bone marrow cells used for "ex-vivo" regional gene therapy for bone repair.

Curr Gene Ther 2015 ;15(5):481-91

University of Southern California, Keck School of Medicine, Department of Orthopaedic Surgery, 1520 San Pablo Street #2000, Los Angeles, CA, 90033, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1566523215666150812120229DOI Listing
May 2016

Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair.

PLoS One 2015 22;10(9):e0138194. Epub 2015 Sep 22.

Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT, United States of America; Department of Genetics and Genome Sciences, University of Connecticut Health Center, Farmington, CT, United States of America.

View Article

Download full-text PDF

Source
https://pdfs.semanticscholar.org/ed89/37d463e07b50086aaa7892
Web Search
http://dx.plos.org/10.1371/journal.pone.0138194
Publisher Site
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0138194PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578922PMC
May 2016

Derivation and Chondrogenic Commitment of Human Embryonic Stem Cell-Derived Mesenchymal Progenitors.

Methods Mol Biol 2015 ;1340:65-78

Department of Genetics and Genome Sciences, UConn Health, 400 Farmington Avenue, Farmington, CT, 06030-6403, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-2938-2_5DOI Listing
April 2016

Differentiation of Human Induced Pluripotent Stem Cells to Chondrocytes.

Methods Mol Biol 2015 ;1340:79-95

Department of Orthopaedic Surgery, MC4037, UConn Health, 263 Farmington Avenue, Farmington, CT, 06030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-2938-2_6DOI Listing
April 2016

PDGF-BB Delays Degeneration of the Intervertebral Discs in a Rabbit Preclinical Model.

Spine (Phila Pa 1976) 2016 Apr;41(8):E449-58

From the UConn Health Center, Department of Orthopaedic Surgery, Farmington, CT.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/BRS.0000000000001336DOI Listing
April 2016

TIEG1 enhances Osterix expression and mediates its induction by TGFβ and BMP2 in osteoblasts.

Biochem Biophys Res Commun 2016 Feb 20;470(3):528-533. Epub 2016 Jan 20.

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2016.01.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4747784PMC
February 2016

Surgical procedures and experimental outcomes of closed fractures in rodent models.

Methods Mol Biol 2015 ;1226:193-211

Department of Orthopaedic Surgery, New England Musculoskeletal Institute, University of Connecticut Health Center, 263 Farmington Avenue, Farmington, CT, 06030, USA,

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/978-1-4939-1619-1_15
Publisher Site
http://dx.doi.org/10.1007/978-1-4939-1619-1_15DOI Listing
June 2015

Relationship between oxidative stress and bone mass in obesity and effects of berry supplementation on bone remodeling in obese male mice: an exploratory study.

J Med Food 2015 Apr 8;18(4):476-82. Epub 2014 Sep 8.

1 Department of Nutritional Sciences, University of Connecticut , Storrs, Connecticut, USA .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/jmf.2013.0182DOI Listing
April 2015

Establishment of human cell type-specific iPS cells with enhanced chondrogenic potential.

Stem Cell Rev Rep 2014 Dec;10(6):820-9

Department of Orthopaedic Surgery, University of Connecticut Health Center, 400 Farmington Avenue, Farmington, CT, 06030, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s12015-014-9538-8DOI Listing
December 2014

Constructing the toolbox: Patient-specific genetic factors of altered fracture healing.

Genes Dis 2014 Dec;1(2):140-148

New England Musculoskeletal Institute and Department of Orthopaedic Surgery.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gendis.2014.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280851PMC
December 2014

PDGF-BB inhibits intervertebral disc cell apoptosis in vitro.

J Orthop Res 2014 Sep 20;32(9):1181-8. Epub 2014 May 20.

Departments of Orthopaedic Surgery, University of Connecticut Health Center, 263 Farmington Avenue, MARB Building, 4th Floor, Farmington, Connecticut, 06030.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jor.22638DOI Listing
September 2014

Increased fracture callus mineralization and strength in cathepsin K knockout mice.

Bone 2014 Sep 10;66:72-81. Epub 2014 Jun 10.

Bone Biology Group, Merck Research Laboratories, West Point, PA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2014.04.032DOI Listing
September 2014

Effects of Wnt5a Haploinsufficiency on Bone Repair.

J Orthop Trauma 2014 Aug;28(8):e191-7

Department of Orthopaedic Surgery, New England Musculoskeletal Institute, University of Connecticut Health Center, Farmington, CT.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/BOT.0000000000000041DOI Listing
August 2014

Altered hematopoietic stem cell and osteoclast precursor frequency in cathepsin K null mice.

J Cell Biochem 2014 Aug;115(8):1449-57

New England Musculoskeletal Institute, University of Connecticut Health Center, Farmington, Connecticut, 06030; Department of Medicine, University of Connecticut Health Center, Farmington, Connecticut, 06030.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.24801DOI Listing
August 2014

Runx1-mediated regulation of osteoclast differentiation and function.

Mol Endocrinol 2014 Apr 25;28(4):546-53. Epub 2014 Feb 25.

New England Musculoskeletal Institute (D.Y.S., J.K., C.E.J.-G., J.L., H.D.), Department of Orthopaedic Surgery (H.D.), and Department of Medicine (C.E.J.-G.), University of Connecticut Health Center, Farmington, Connecticut 06030; and Department of Orthopaedic Surgery and Biochemistry and Molecular Biology (S.K.B., B.F.), University of Southern California, Los Angeles, California 90089.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/me.2013-1305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968404PMC
April 2014

Epigenetic regulation of miR-302 by JMJD1C inhibits neural differentiation of human embryonic stem cells.

J Biol Chem 2014 Jan 6;289(4):2384-95. Epub 2013 Dec 6.

From the Department of Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut 06030 and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M113.535799DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900981PMC
January 2014

Functional role of Runx3 in the regulation of aggrecan expression during cartilage development.

J Cell Physiol 2013 Nov;228(11):2232-42

Orthopaedic Research Laboratory, Department of Orthopedic Surgery, Boston University School of Medicine, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.24396DOI Listing
November 2013

Effects of pharmacological inhibition of cathepsin K on fracture repair in mice.

Bone 2013 Jul 26;55(1):248-55. Epub 2013 Feb 26.

New England Musculoskeletal Institute, University of Connecticut Health Center, Farmington, CT 06030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2013.02.010DOI Listing
July 2013

Increased mandibular condylar growth in mice with estrogen receptor beta deficiency.

J Bone Miner Res 2013 May;28(5):1127-34

Division of Orthodontics, Columbia University College of Dental Medicine, New York, NY 10032, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbmr.1835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601565PMC
May 2013

Efficient differentiation of human iPSC-derived mesenchymal stem cells to chondroprogenitor cells.

J Cell Biochem 2013 Feb;114(2):480-90

Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.24388DOI Listing
February 2013

ALX4 gain-of-function mutations in nonsyndromic craniosynostosis.

Hum Mutat 2012 Dec 13;33(12):1626-9. Epub 2012 Aug 13.

Section of Genetics, Department of Pediatrics, University of California-Davis, Sacramento, CA 95817, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.22166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495992PMC
December 2012

Runx1 dose-dependently regulates endochondral ossification during skeletal development and fracture healing.

J Bone Miner Res 2012 Jul;27(7):1585-97

Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT 06034, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbmr.1601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377839PMC
July 2012

Ski inhibits TGF-β/phospho-Smad3 signaling and accelerates hypertrophic differentiation in chondrocytes.

J Cell Biochem 2012 Jun;113(6):2156-66

Department of Orthopaedics and Rehabilitation, Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Avenue Box 665, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.24089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324639PMC
June 2012

Persistent expression of Twist1 in chondrocytes causes growth plate abnormalities and dwarfism in mice.

Int J Dev Biol 2011 ;55(6):641-7

Department of Orthopaedic Surgery, University of Connecticut Health Center, Farmington, CT 06030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1387/ijdb.103274rgDOI Listing
March 2012

Roles of SATB2 in osteogenic differentiation and bone regeneration.

Tissue Eng Part A 2011 Jul 21;17(13-14):1767-76. Epub 2011 Apr 21.

Division of Oral Biology, Department of General Dentistry, Tufts University School of Dental Medicine, Boston, Massachusetts 02111, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/ten.TEA.2010.0503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118613PMC
July 2011

Wnt5b regulates mesenchymal cell aggregation and chondrocyte differentiation through the planar cell polarity pathway.

J Cell Physiol 2011 Jun;226(6):1683-93

Department of Orthopeadic Surgery, University of Connecticut Health Center, Farmington, Connecticut 06062, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.22499DOI Listing
June 2011

"Same day" ex-vivo regional gene therapy: a novel strategy to enhance bone repair.

Mol Ther 2011 May 22;19(5):960-8. Epub 2011 Feb 22.

New England Musculoskeletal Institute, Department of Orthopedic Surgery, University of Connecticut Health Center, Farmington, Connecticut 06030-5456, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/mt.2011.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098640PMC
May 2011

Integration of phosphatidylinositol 3-kinase, Akt kinase, and Smad signaling pathway in BMP-2-induced osterix expression.

Calcif Tissue Int 2010 Dec 26;87(6):533-40. Epub 2010 Sep 26.

Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00223-010-9419-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3055166PMC
December 2010

WNT5A regulates chondrocyte differentiation through differential use of the CaN/NFAT and IKK/NF-kappaB pathways.

Mol Endocrinol 2010 Aug 23;24(8):1581-93. Epub 2010 Jun 23.

Department of Orthopeadic Surgery, University of Connecticut Health Center, Farmington, Connecticut 06062, USA.

View Article

Download full-text PDF

Source
https://academic.oup.com/mend/article-lookup/doi/10.1210/me.
Publisher Site
http://dx.doi.org/10.1210/me.2010-0037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417459PMC
August 2010

Rapid isolation of human stem cells (connective tissue progenitor cells) from the proximal humerus during arthroscopic rotator cuff surgery.

Am J Sports Med 2010 Jul 7;38(7):1438-47. Epub 2010 Apr 7.

University of Connecticut, Department of Orthopaedic Surgery, Farmington, CT 06034, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/0363546509360924DOI Listing
July 2010

Titanium particles stimulate COX-2 expression in synovial fibroblasts through an oxidative stress-induced, calpain-dependent, NF-kappaB pathway.

Am J Physiol Cell Physiol 2009 Aug 3;297(2):C310-20. Epub 2009 Jun 3.

Center for Musculoskeletal Research, Univ. of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpcell.00597.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2724098PMC
August 2009

Prostaglandin E2 inhibits BMP signaling and delays chondrocyte maturation.

J Orthop Res 2009 Jun;27(6):785-92

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jor.20805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737521PMC
June 2009

Effect of lamin A/C knockdown on osteoblast differentiation and function.

J Bone Miner Res 2009 Feb;24(2):283-93

Division of Experimental Medicine, Department of Medicine, McGill University, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1359/jbmr.081010DOI Listing
February 2009

Exported 18-kDa isoform of fibroblast growth factor-2 is a critical determinant of bone mass in mice.

J Biol Chem 2009 Jan 4;284(5):3170-82. Epub 2008 Dec 4.

Department of Medicine, University of Connecticut Health Center, Farmington, CT 06030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M804900200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631953PMC
January 2009

Teriparatide (1-34 human PTH) regulation of osterix during fracture repair.

J Cell Biochem 2008 Sep;105(1):219-26

The Center for Musculoskeletal Research, University of Rochester, Rochester, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.21816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337675PMC
September 2008

Murine and chicken chondrocytes regulate osteoclastogenesis by producing RANKL in response to BMP2.

J Bone Miner Res 2008 Mar;23(3):314-25

Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1359/jbmr.071025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2636701PMC
March 2008

Osterix/Sp7 regulates mesenchymal stem cell mediated endochondral ossification.

J Cell Physiol 2008 Jan;214(1):173-82

The Center for Musculoskeletal Research, University of Rochester, Rochester, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.21176DOI Listing
January 2008

Quantitative mouse model of implant-associated osteomyelitis and the kinetics of microbial growth, osteolysis, and humoral immunity.

J Orthop Res 2008 Jan;26(1):96-105

The Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Avenue, Box 665, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jor.20452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2701346PMC
January 2008

Transforming growth factor-beta and Wnt signals regulate chondrocyte differentiation through Twist1 in a stage-specific manner.

Mol Endocrinol 2007 Nov 7;21(11):2805-20. Epub 2007 Aug 7.

Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/me.2007-0199DOI Listing
November 2007

Lead induces chondrogenesis and alters transforming growth factor-beta and bone morphogenetic protein signaling in mesenchymal cell populations.

Environ Health Perspect 2007 Sep;115(9):1276-82

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1289/ehp.10028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1964910PMC
September 2007

Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation.

J Bone Miner Res 2007 Aug;22(8):1260-70

Center for Musculoskeletal Research, University of Rochester, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1359/jbmr.070502DOI Listing
August 2007

Environmental agents affect skeletal growth and development.

Birth Defects Res C Embryo Today 2007 Mar;81(1):41-50

Department of Orthopaedics and the Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/bdrc.20087DOI Listing
March 2007

Wnt induction of chondrocyte hypertrophy through the Runx2 transcription factor.

J Cell Physiol 2006 Jul;208(1):77-86

Center for Musculoskeletal Research, University of Rochester, Rochester, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.20656DOI Listing
July 2006

Transforming growth factor-beta stimulates cyclin D1 expression through activation of beta-catenin signaling in chondrocytes.

J Biol Chem 2006 Jul 10;281(30):21296-304. Epub 2006 May 10.

Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M600514200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649822PMC
July 2006

Cyclin D1-cdk4 induce runx2 ubiquitination and degradation.

J Biol Chem 2006 Jun 13;281(24):16347-53. Epub 2006 Apr 13.

Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester School of Medicine, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M603439200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649830PMC
June 2006

Runx2-mediated regulation of the zinc finger Osterix/Sp7 gene.

Gene 2006 May 29;372:62-70. Epub 2006 Mar 29.

Center for Musculoskeletal Research, Department of Orthopaedics, Box 665, University of Rochester Medical Center, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.gene.2005.12.022DOI Listing
May 2006

Safety and efficacy of ultraviolet-a light-activated gene transduction for gene therapy of articular cartilage defects.

J Bone Joint Surg Am 2006 Apr;88(4):753-61

The Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2106/JBJS.E.00400DOI Listing
April 2006

Autoimmunity and bone.

Ann N Y Acad Sci 2006 Apr;1068:275-83

Department of Orthopaedics, University of Rochester Medical Center, 601 Elmwood Avenue, Box 665, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1196/annals.1346.031
Publisher Site
http://dx.doi.org/10.1196/annals.1346.031DOI Listing
April 2006

COX-2 has a critical role during incorporation of structural bone allografts.

Ann N Y Acad Sci 2006 Apr;1068:532-42

Department of Orthopedics, The Center for Musculoskeletal Research, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1196/annals.1346.012DOI Listing
April 2006

Smad7 mediates inhibition of Saos2 osteosarcoma cell differentiation by NFkappaB.

Exp Cell Res 2006 Jan 2;312(1):40-50. Epub 2005 Nov 2.

Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2005.09.016DOI Listing
January 2006

Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation.

J Bone Miner Res 2006 Jan 19;21(1):4-16. Epub 2005 Sep 19.

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1359/JBMR.050911
Publisher Site
http://dx.doi.org/10.1359/JBMR.050911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649698PMC
January 2006

Increased radiation-induced apoptosis of Saos2 cells via inhibition of NFkappaB: a role for c-Jun N-terminal kinase.

J Cell Biochem 2005 Dec;96(6):1262-73

Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.20607DOI Listing
December 2005

Runx1/AML1/Cbfa2 mediates onset of mesenchymal cell differentiation toward chondrogenesis.

J Bone Miner Res 2005 Sep 23;20(9):1624-36. Epub 2005 May 23.

Center for Musculoskeletal Research, Department of Orthopeadics, University of Rochester, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1359/JBMR.050516DOI Listing
September 2005

Wnt-mediated regulation of chondrocyte maturation: modulation by TGF-beta.

J Cell Biochem 2005 Aug;95(5):1057-68

Center for Musculoskeletal Research, University of Rochester Medical Center, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.20466DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2649667PMC
August 2005

Fibroblasts express RANKL and support osteoclastogenesis in a COX-2-dependent manner after stimulation with titanium particles.

J Bone Miner Res 2005 Jul 14;20(7):1136-48. Epub 2005 Feb 14.

Center for Musculoskeletal Research University of Rochester, School of Medicine and Dentistry, Rochester, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1359/JBMR.050206DOI Listing
July 2005

Transcriptional regulation of chondrocyte maturation: potential involvement of transcription factors in OA pathogenesis.

Mol Aspects Med 2005 Jun;26(3):169-79

The Center for Musculoskeletal Research, University of Rochester, Rochester, NY 14642, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mam.2005.01.003DOI Listing
June 2005

Differential regulation of EP receptor isoforms during chondrogenesis and chondrocyte maturation.

Biochem Biophys Res Commun 2005 Mar;328(3):764-76

Center for Musculoskeletal Research, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbrc.2004.11.074DOI Listing
March 2005

PGE2 inhibits chondrocyte differentiation through PKA and PKC signaling.

Exp Cell Res 2004 Oct;300(1):159-69

Center for Musculoskeletal Research, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2004.06.019DOI Listing
October 2004

Parathyroid hormone-related peptide (PTHrP) inhibits Runx2 expression through the PKA signaling pathway.

Exp Cell Res 2004 Sep;299(1):128-36

Department of Orthopaedics, The Center for Musculoskeletal Research, University of Rochester, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.yexcr.2004.05.025DOI Listing
September 2004

Transforming growth factor-beta1 induced alteration of skeletal morphogenesis in vivo.

J Orthop Res 2004 Jul;22(4):687-96

Department of Orthopaedics, Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave., Box 665, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.orthres.2003.10.023DOI Listing
July 2004

5-azacytidine alters TGF-beta and BMP signaling and induces maturation in articular chondrocytes.

J Cell Biochem 2004 May;92(2):316-31

Center for Musculoskeletal Research, Department of Orthopaedics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.20050DOI Listing
May 2004

CREB Cooperates with BMP-stimulated Smad signaling to enhance transcription of the Smad6 promoter.

J Cell Physiol 2004 Mar;198(3):428-40

Center for Musculoskeletal Research, University of Rochester, School of Medicine and Dentistry, Rochester, New York, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.10421DOI Listing
March 2004

Runx2/Cbfa1 functions: diverse regulation of gene transcription by chromatin remodeling and co-regulatory protein interactions.

Connect Tissue Res 2003 ;44 Suppl 1:141-8

Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655-0106, USA.

View Article

Download full-text PDF

Source
January 2004

Runx2/Cbfa1 stimulation by retinoic acid is potentiated by BMP2 signaling through interaction with Smad1 on the collagen X promoter in chondrocytes.

J Cell Biochem 2003 Dec;90(6):1287-98

The Center for Musculoskeletal Research, University of Rochester, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.10677DOI Listing
December 2003

Smad6 is induced by BMP-2 and modulates chondrocyte differentiation.

J Orthop Res 2003 Sep;21(5):908-13

Center for Musculoskeletal Research, Department of Orthopaedics, University of Rochester Medical Center, 601 Elmwood Avenue, Box 665, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0736-0266(03)00008-1DOI Listing
September 2003

Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo.

J Cell Physiol 2003 Aug;196(2):301-11

Department of Cell Biology, University of Massachusetts Medical School, Worcester, Massachusetts 01655-0106, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.10316DOI Listing
August 2003

ATF-2 cooperates with Smad3 to mediate TGF-beta effects on chondrocyte maturation.

Exp Cell Res 2003 Aug;288(1):198-207

Center for Musculoskeletal Research, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0014-4827(03)00181-2DOI Listing
August 2003

Retinoic acid stimulates chondrocyte differentiation and enhances bone morphogenetic protein effects through induction of Smad1 and Smad5.

Endocrinology 2003 Jun;144(6):2514-23

Center for Musculoskeletal Research, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2002-220969DOI Listing
June 2003

Phenotype discovery by gene expression profiling: mapping of biological processes linked to BMP-2-mediated osteoblast differentiation.

J Cell Biochem 2003 May;89(2):401-26

Department of Cell Biology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655-0106, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcb.10515DOI Listing
May 2003

Transcription factors RUNX1/AML1 and RUNX2/Cbfa1 dynamically associate with stationary subnuclear domains.

J Cell Sci 2002 Nov;115(Pt 21):4167-76

Department of Cell Biology and Cancer Center, University of Massachusetts Medical School, Worcester, Massachusetts 01655-0106, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.00095DOI Listing
November 2002