Publications by authors named "Heth R Turnquist"

56Publications

Matrix bound nanovesicle-associated IL-33 activates a pro-remodeling macrophage phenotype via a non-canonical, ST2-independent pathway.

J Immunol Regen Med 2019 Mar 1;3:26-35. Epub 2019 Feb 1.

McGowan Institute for Regenerative Medicine, University of Pittsburgh, 450 Technology Drive, Suite 300, Pittsburgh, PA 15219-3110, USA.

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http://dx.doi.org/10.1016/j.regen.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814021PMC
March 2019

Interleukin-33 contributes to ILC2 activation and early inflammation-associated lung injury during abdominal sepsis.

Immunol Cell Biol 2018 10 17;96(9):935-947. Epub 2018 May 17.

Department of Surgery, University of Pittsburgh, Pittsburgh, PA, 15213, USA.

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http://dx.doi.org/10.1111/imcb.12159DOI Listing
October 2018

IL-33 Drives Monocyte Recruitment to Lung Interstitium through Chemokine Upregulation.

Immunohorizons 2017 Aug 15;1(6):101-108. Epub 2017 Aug 15.

Committee on Immunology, University of Chicago, Chicago, IL 60637.

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http://dx.doi.org/10.4049/immunohorizons.1700024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5889047PMC
August 2017

IL-33 exacerbates liver sterile inflammation by amplifying neutrophil extracellular trap formation.

J Hepatol 2017 Sep 21. Epub 2017 Sep 21.

Department of Surgery, University of Pittsburgh, Pittsburgh, PA, United States; Department of Surgery, Union Hospital, Huazhong University of Science and Technology, Wuhan, PR China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01688278173229
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http://dx.doi.org/10.1016/j.jhep.2017.09.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862757PMC
September 2017

Role of the IL-33-ST2 axis in sepsis.

Mil Med Res 2017 2;4. Epub 2017 Feb 2.

Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213 USA.

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http://mmrjournal.biomedcentral.com/articles/10.1186/s40779-
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http://dx.doi.org/10.1186/s40779-017-0115-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5288881PMC
July 2018

Peri-alloHCT IL-33 administration expands recipient T-regulatory cells that protect mice against acute GVHD.

Blood 2016 07 24;128(3):427-39. Epub 2016 May 24.

Starzl Transplantation Institute and Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1182/blood-2015-12-684142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4957164PMC
July 2016

Identity Crisis.

Transplantation 2016 Feb;100(2):258-9

1 Starzl Transplantation Institute, Department of Surgery and Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

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http://dx.doi.org/10.1097/TP.0000000000001078DOI Listing
February 2016

Controlling the burn and fueling the fire: defining the role for the alarmin interleukin-33 in alloimmunity.

Curr Opin Organ Transplant 2016 Feb;21(1):45-52

aThomas E. Starzl Transplantation Institute and Department of Surgery, Pittsburgh, Pennsylvania, USA bDepartment of Cardiovascular Surgery, Second Affiliated Hospital of Harbin Medical University, Harbin, China cDepartment of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania , USA.

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http://dx.doi.org/10.1097/MOT.0000000000000265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704690PMC
February 2016

Expansion of Regulatory T Cells In Vitro and In Vivo by IL-33.

Methods Mol Biol 2016 ;1371:29-41

Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA, 15213, USA.

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http://link.springer.com/content/pdf/10.1007%2F978-1-4939-31
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http://link.springer.com/10.1007/978-1-4939-3139-2_3
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http://dx.doi.org/10.1007/978-1-4939-3139-2_3DOI Listing
August 2016

mTORC2 Deficiency in Myeloid Dendritic Cells Enhances Their Allogeneic Th1 and Th17 Stimulatory Ability after TLR4 Ligation In Vitro and In Vivo.

J Immunol 2015 May 3;194(10):4767-76. Epub 2015 Apr 3.

Department of Surgery, Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261

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http://dx.doi.org/10.4049/jimmunol.1402551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417394PMC
May 2015

New dog and new tricks: evolving roles for IL-33 in type 2 immunity.

J Leukoc Biol 2015 Jun 23;97(6):1037-48. Epub 2015 Mar 23.

*Starzl Transplantation Institute, Departments of Surgery, Immunology, and Dermatology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA

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http://dx.doi.org/10.1189/jlb.3RI1214-595RDOI Listing
June 2015

IL-33 is an unconventional Alarmin that stimulates IL-2 secretion by dendritic cells to selectively expand IL-33R/ST2+ regulatory T cells.

J Immunol 2014 Oct 12;193(8):4010-20. Epub 2014 Sep 12.

Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261

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http://dx.doi.org/10.4049/jimmunol.1400481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185240PMC
October 2014

Low TCR signal strength induces combined expansion of Th2 and regulatory T cell populations that protect mice from the development of type 1 diabetes.

Diabetologia 2014 Jul 16;57(7):1428-36. Epub 2014 Apr 16.

Department of Immunology, University of Pittsburgh, BST W1151, 200 Lothrop Street, Pittsburgh, PA, 15261, USA.

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http://dx.doi.org/10.1007/s00125-014-3233-9DOI Listing
July 2014

A window into immunosuppressant immunoregulation: recipient conversion to rapamycin increases potentially tolerogenic immune cells.

Kidney Int 2014 Apr;85(4):743-5

1] Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA [2] Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA [3] Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ki.2013.420DOI Listing
April 2014

Cutting edge: Flt3 ligand mediates STAT3-independent expansion but STAT3-dependent activation of myeloid-derived suppressor cells.

J Immunol 2014 Apr 17;192(8):3470-3. Epub 2014 Mar 17.

Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213;

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1300058
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http://dx.doi.org/10.4049/jimmunol.1300058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994403PMC
April 2014

IL-12hi rapamycin-conditioned dendritic cells mediate IFN-γ-dependent apoptosis of alloreactive CD4+ T cells in vitro and reduce lethal graft-versus-host disease.

Biol Blood Marrow Transplant 2014 Feb 12;20(2):192-201. Epub 2013 Nov 12.

Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2013.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3964782PMC
February 2014

Regulatory myeloid cells in transplantation.

Transplantation 2014 Feb;97(4):367-79

1 Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA. 2 Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA. 3 Address correspondence to: Angus W. Thomson, Ph.D., D.Sc., Departments of Surgery and Immunology, University of Pittsburgh School of Medicine, Thomas E. Starzl Transplantation Institute, 200 Lothrop Street, Biomedical Science Tower W1540, Pittsburgh, PA 15213.

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http://dx.doi.org/10.1097/TP.0b013e3182a860deDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944083PMC
February 2014

Implications for Interleukin-33 in solid organ transplantation.

Cytokine 2013 May 27;62(2):183-94. Epub 2013 Mar 27.

Thomas E. Starzl Transplantation Institute and Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.cyto.2013.02.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640740PMC
May 2013

Dendritic cells and regulation of graft-versus-host disease and graft-versus-leukemia activity.

Blood 2012 May 7;119(22):5088-103. Epub 2012 Mar 7.

Starzl Transplantation Institute, Departments of Surgery and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA.

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http://dx.doi.org/10.1182/blood-2011-11-364091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369606PMC
May 2012

Histone deacetylase inhibition facilitates GM-CSF-mediated expansion of myeloid-derived suppressor cells in vitro and in vivo.

J Leukoc Biol 2012 May 25;91(5):701-9. Epub 2011 Oct 25.

University of Pittsburgh School of Medicine, Thomas E. Starzl Transplantation Institute, 200 Lothrop St., Biomedical Science Tower, W1540, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1189/jlb.0311119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046249PMC
May 2012

IL-33 broadens its repertoire to affect DC.

Eur J Immunol 2009 Dec;39(12):3292-5

Department of Surgery, Thomas E. Starzl Transplantation Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1002/eji.200940026DOI Listing
December 2009

Dendritic cell immunobiology in relation to liver transplant outcome.

Front Biosci (Elite Ed) 2009 Jun 1;1:99-114. Epub 2009 Jun 1.

Starzl Transplantation Institute and Department of Surgery, University of Pittsburgh School of Medicine, 200 Lothrop Street, BST W1540, Pittsburgh, PA 15261, USA.

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June 2009

Tolerogenic dendritic cell-regulatory T-cell interaction and the promotion of transplant tolerance.

Transplantation 2009 May;87(9 Suppl):S86-90

Thomas E. Starzl Transplantation Institute and Department of Surgery, University of Pittsburgh, School of Medicine, Pittsburgh, PA 15261, USA.

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https://insights.ovid.com/crossref?an=00007890-200905151-000
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http://dx.doi.org/10.1097/TP.0b013e3181a2dcecDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746709PMC
May 2009

Immunoregulatory functions of mTOR inhibition.

Nat Rev Immunol 2009 May;9(5):324-37

Starzl Transplantation Institute and Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1038/nri2546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847476PMC
May 2009

Use of rapamycin in the induction of tolerogenic dendritic cells.

Handb Exp Pharmacol 2009 (188):215-32

Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1007/978-3-540-71029-5_10DOI Listing
February 2009

Taming the lions: manipulating dendritic cells for use as negative cellular vaccines in organ transplantation.

Curr Opin Organ Transplant 2008 Aug;13(4):350-7

Thomas E. Starzl Transplantation Institute, Pittsburgh, USA.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MOT.0b013e328306116cDOI Listing
August 2008

IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells.

J Immunol 2008 Jul;181(1):62-72

Thomas E. Starzl Transplantation Institute and Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796738PMC
http://dx.doi.org/10.4049/jimmunol.181.1.62DOI Listing
July 2008

Frontiers of immunological tolerance.

Methods Mol Biol 2007 ;380:1-24

University of Pittsburgh School of Medicine, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1007/978-1-59745-395-0_1DOI Listing
April 2008

Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques.

Transplantation 2007 Jul;84(2):196-206

Thomas E. Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1097/01.tp.0000268582.21168.f6DOI Listing
July 2007

CCL21 is an effective surgical neoadjuvant for treatment of mammary tumors.

Cancer Biol Ther 2007 Aug 7;6(8):1206-10. Epub 2007 May 7.

Eppley Institute, Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, Nebraska 68198-6805, USA.

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http://dx.doi.org/10.4161/cbt.6.8.4405DOI Listing
August 2007

Flt3 ligand delivered in a pluronic formulation prolongs the survival of mice with orthotopic pancreatic adenocarcinoma.

Cancer Biother Radiopharm 2007 Apr;22(2):235-8

Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE 68198-6805, USA.

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http://www.liebertpub.com/doi/10.1089/cbr.2007.336
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http://dx.doi.org/10.1089/cbr.2007.336DOI Listing
April 2007

CCL21 induces extensive intratumoral immune cell infiltration and specific anti-tumor cellular immunity.

Int J Oncol 2007 Mar;30(3):631-9

Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, NE 68198, USA.

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March 2007

CCL21-induced immune cell infiltration.

Int Immunopharmacol 2007 Feb 13;7(2):272-6. Epub 2006 Nov 13.

Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE 68198, USA.

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http://dx.doi.org/10.1016/j.intimp.2006.10.004DOI Listing
February 2007

Tapasin decreases immune responsiveness to a model tumor antigen.

J Clin Immunol 2004 Jul;24(4):462-70

Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, NE 68198-6805, USA.

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http://dx.doi.org/10.1023/B:JOCI.0000029118.51587.d9DOI Listing
July 2004

The Ig-like domain of tapasin influences intermolecular interactions.

J Immunol 2004 Mar;172(5):2976-84

Eppley Institute for Research in Cancer and Allied Diseases, Department of Pathology, University of Nebraska Medical Center, Omaha, NE 68198, USA.

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http://dx.doi.org/10.4049/jimmunol.172.5.2976DOI Listing
March 2004

The amyloid precursor-like protein 2 and the adenoviral E3/19K protein both bind to a conformational site on H-2Kd and regulate H-2Kd expression.

J Biol Chem 2003 Apr 27;278(15):12618-23. Epub 2002 Dec 27.

Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA.

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http://dx.doi.org/10.1074/jbc.M208203200DOI Listing
April 2003

HLA class I polymorphism has a dual impact on ligand binding and chaperone interaction.

Hum Immunol 2002 Apr;63(4):248-55

Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.

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http://dx.doi.org/10.1016/s0198-8859(02)00364-6DOI Listing
April 2002

Expression of invariant chain can cause an allele-dependent increase in the surface expression of MHC class I molecules.

Immunogenetics 2002 May 23;54(2):74-81. Epub 2002 Mar 23.

Eppley Institute for Research in Cancer and Allied Diseases, Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, NE 68198-6805, USA.

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http://dx.doi.org/10.1007/s00251-002-0446-8DOI Listing
May 2002

The interface between tapasin and MHC class I: identification of amino acid residues in both proteins that influence their interaction.

Immunol Res 2002 ;25(3):261-9

Eppley Institute for Research in Cancer and Allied Diseases, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198-6805, USA.

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http://dx.doi.org/10.1385/ir:25:3:261DOI Listing
November 2002

Disparate binding of chaperone proteins by HLA-A subtypes.

Immunogenetics 2002 Feb 22;53(10-11):830-4. Epub 2002 Jan 22.

Eppley Institute for Research in Cancer and Allied Diseases, Department of Pathology and Microbiology, University of Nebraska Medical Center, 986805 Nebraska Medical Center, Omaha, NE 68198-6805 USA.

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http://dx.doi.org/10.1007/s00251-001-0404-xDOI Listing
February 2002