Publications by authors named "Herve Le Marec"

70Publications

Gap-134, a Connexin43 activator, prevents age-related development of ventricular fibrosis in Scn5a mice.

Pharmacol Res 2020 09 25;159:104922. Epub 2020 May 25.

Université De Nantes, CNRS, INSERM, l'institut du thorax, F-44000, Nantes, France. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2020.104922DOI Listing
September 2020

Genetics of syndromic and non-syndromic mitral valve prolapse.

Heart 2018 06 19;104(12):978-984. Epub 2018 Jan 19.

l'institut du thorax, INSERM, CNRS, Université de Nantes, Nantes, France.

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http://dx.doi.org/10.1136/heartjnl-2017-312420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168077PMC
June 2018

Brugada syndrome: Diagnosis, risk stratification and management.

Arch Cardiovasc Dis 2017 Mar 27;110(3):188-195. Epub 2017 Jan 27.

l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, Nantes, France.

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http://dx.doi.org/10.1016/j.acvd.2016.09.009DOI Listing
March 2017

The Brugada Syndrome: A Rare Arrhythmia Disorder with Complex Inheritance.

Front Cardiovasc Med 2016 25;3. Epub 2016 Apr 25.

Service de Cardiologie, Centre Hospitalier Universitaire (CHU) de Nantes, l'institut du thorax, Nantes, France; Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1087, l'institut du thorax, Nantes, France; Centre National de la Recherche Scientifique (CNRS) UMR 6291, l'institut du thorax, Nantes, France; l'institut du thorax, Université de Nantes, Nantes, France.

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http://dx.doi.org/10.3389/fcvm.2016.00009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842929PMC
May 2016

Identification of novel APOB mutations by targeted next-generation sequencing for the molecular diagnosis of familial hypobetalipoproteinemia.

Atherosclerosis 2016 07 11;250:52-6. Epub 2016 Apr 11.

INSERM, UMR1087, l'institut du thorax, Nantes, F-44000, France; CNRS, UMR 6291, Nantes, F-44000, France; Université de Nantes, Nantes, F-44000, France; CHU Nantes, l'institut du Thorax, Nantes, F-44000, France; CIC Thorax, CHU Nantes, l'institut du Thorax, Nantes, F-44000, France. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.04.010DOI Listing
July 2016

Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I.

Int J Cardiol 2016 Mar 11;207:349-58. Epub 2016 Jan 11.

Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1087, l'institut du thorax, Nantes, France; Centre National de la Recherche Scientifique (CNRS) UMR 6291, l'institut du thorax, Nantes, France; Université de Nantes, l'institut du thorax, Nantes, France; Centre Hospitalier Universitaire (CHU) de Nantes, l'institut du thorax, Service de Cardiologie, Nantes, France. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.01.052DOI Listing
March 2016

Fine-scale human genetic structure in Western France.

Eur J Hum Genet 2015 Jun 3;23(6):831-6. Epub 2014 Sep 3.

1] INSERM UMR 1087, Nantes, France [2] CNRS, UMR 6291 institut du thorax, Nantes, France [3] Université de Nantes, Nantes, France [4] CHU Nantes, l'institut du thorax, Service de Cardiologie, Nantes, France.

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http://dx.doi.org/10.1038/ejhg.2014.175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795055PMC
June 2015

Correlation of intracardiac electrogram with surface electrocardiogram in Brugada syndrome patients.

Europace 2014 Jun 25;16(6):908-13. Epub 2013 Sep 25.

Saint Jude Medical, 15900 Valley View Court Sylmar, CA 91342, USA.

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http://dx.doi.org/10.1093/europace/eut294DOI Listing
June 2014

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.

Nat Genet 2013 Sep 21;45(9):1044-9. Epub 2013 Jul 21.

Department of Clinical and Experimental Cardiology, Heart Failure Research Center, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng.2712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869788PMC
September 2013

Risk Stratification and Therapeutic Approach in Brugada Syndrome.

Arrhythm Electrophysiol Rev 2012 Sep;1(1):17-21

Professor of Cardiology and Head, Thorax Institute, Nantes, France.

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http://dx.doi.org/10.15420/aer.2012.1.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711526PMC
September 2012

Copenhagen city heart study: more mermaids than Brugada's patients in Copenhagen.

Europace 2010 Jul 27;12(7):923-4. Epub 2010 May 27.

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http://dx.doi.org/10.1093/europace/euq143DOI Listing
July 2010

Brugada syndrome: where are you?

Europace 2009 Oct;11(10):1260-1

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http://dx.doi.org/10.1093/europace/eup267DOI Listing
October 2009

Response to intravenous ajmaline: a retrospective analysis of 677 ajmaline challenges.

Europace 2009 Oct 9;11(10):1345-52. Epub 2009 Jul 9.

11st Department of Medicine-Cardiology, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

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http://dx.doi.org/10.1093/europace/eup189DOI Listing
October 2009

Ajmaline challenge: to stop or not to stop...

Heart Rhythm 2009 May 11;6(5):632-3. Epub 2009 Mar 11.

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http://dx.doi.org/10.1016/j.hrthm.2009.03.009DOI Listing
May 2009

14-3-3 is a regulator of the cardiac voltage-gated sodium channel Nav1.5.

Circ Res 2006 Jun 25;98(12):1538-46. Epub 2006 May 25.

Inserm UMR533, Université de Nantes, Nantes Atlantique Universités, l'Institut du thorax, Faculté de Médecine, France.

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http://dx.doi.org/10.1161/01.RES.0000229244.97497.2cDOI Listing
June 2006

Monomorphic ventricular tachycardia due to Brugada syndrome successfully treated by hydroquinidine therapy in a 3-year-old child.

J Cardiovasc Electrophysiol 2006 Jan;17(1):97-100

Department of Cardiology and Unité INSERM U533, Institut du thorax, CHU de Nantes, Nantes, France.

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http://dx.doi.org/10.1111/j.1540-8167.2005.00329.xDOI Listing
January 2006

A common antitussive drug, clobutinol, precipitates the long QT syndrome 2.

Mol Pharmacol 2004 Nov 27;66(5):1093-102. Epub 2004 Jul 27.

l'Institut du thorax, Institut National de la Sante et de la Recherche Medicale U533, Nantes, France.

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http://dx.doi.org/10.1124/mol.104.001065DOI Listing
November 2004

[Prevention of cardiac arrhythmias: what is the place for antiarrhythmic drugs?].

Rev Prat 2004 Feb;54(3):286-90

Clinique cardiologique et des maladies vasculaires, CHU de Nantes-Hôpital G. et R. Laennec, 44093 Nantes Cedex 1.

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February 2004

Cardiac retention of [11C]HED in genotyped long QT patients: a potential amplifier role for severity of the disease.

Am J Physiol Heart Circ Physiol 2003 Sep 29;285(3):H1286-93. Epub 2003 May 29.

Centre d'Exploration et de Recherche Médicales par Emission de Positons, 69003 Lyon, France.

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http://dx.doi.org/10.1152/ajpheart.00276.2003DOI Listing
September 2003

Na+ channel mutation leading to loss of function and non-progressive cardiac conduction defects.

J Mol Cell Cardiol 2003 May;35(5):549-57

Department of Medical Physiology, University Medical Center, Universiteitsweg 100, 3584CG, The, Utrecht, Netherlands.

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http://dx.doi.org/10.1016/s0022-2828(03)00078-6DOI Listing
May 2003

Novel brugada SCN5A mutation leading to ST segment elevation in the inferior or the right precordial leads.

J Cardiovasc Electrophysiol 2003 Feb;14(2):200-3

Institut National de la Santé et de la Recherche Médicale (INSERM) U533, Faculté de Médecine, the Cardiology Department, Hôpital G&R Laennec, Nantes, France.

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http://dx.doi.org/10.1046/j.1540-8167.2003.02382.xDOI Listing
February 2003

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death.

Nature 2003 Feb;421(6923):634-9

Howard Hughes Medical Institute and Departments of Cell Biology, Biochemistry, and Neuroscience, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1038/nature01335DOI Listing
February 2003