Herve Le Marec

Herve Le Marec

UNVERIFIED PROFILE

Are you Herve Le Marec?   Register this Author

Register author
Herve Le Marec

Herve Le Marec

Publications by authors named "Herve Le Marec"

Are you Herve Le Marec?   Register this Author

69Publications

2273Reads

24Profile Views

Genetics of syndromic and non-syndromic mitral valve prolapse.

Heart 2018 06 19;104(12):978-984. Epub 2018 Jan 19.

l'institut du thorax, INSERM, CNRS, Université de Nantes, Nantes, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/heartjnl-2017-312420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168077PMC
June 2018

Brugada syndrome: Diagnosis, risk stratification and management.

Arch Cardiovasc Dis 2017 Mar 27;110(3):188-195. Epub 2017 Jan 27.

l'Institut du Thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, Nantes, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.acvd.2016.09.009DOI Listing
March 2017

Identification of novel APOB mutations by targeted next-generation sequencing for the molecular diagnosis of familial hypobetalipoproteinemia.

Atherosclerosis 2016 07 11;250:52-6. Epub 2016 Apr 11.

INSERM, UMR1087, l'institut du thorax, Nantes, F-44000, France; CNRS, UMR 6291, Nantes, F-44000, France; Université de Nantes, Nantes, F-44000, France; CHU Nantes, l'institut du Thorax, Nantes, F-44000, France; CIC Thorax, CHU Nantes, l'institut du Thorax, Nantes, F-44000, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2016.04.010DOI Listing
July 2016

The Brugada Syndrome: A Rare Arrhythmia Disorder with Complex Inheritance.

Front Cardiovasc Med 2016 25;3. Epub 2016 Apr 25.

Service de Cardiologie, Centre Hospitalier Universitaire (CHU) de Nantes, l'institut du thorax, Nantes, France; Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1087, l'institut du thorax, Nantes, France; Centre National de la Recherche Scientifique (CNRS) UMR 6291, l'institut du thorax, Nantes, France; l'institut du thorax, Université de Nantes, Nantes, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fcvm.2016.00009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842929PMC
May 2016

Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I.

Int J Cardiol 2016 Mar 11;207:349-58. Epub 2016 Jan 11.

Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1087, l'institut du thorax, Nantes, France; Centre National de la Recherche Scientifique (CNRS) UMR 6291, l'institut du thorax, Nantes, France; Université de Nantes, l'institut du thorax, Nantes, France; Centre Hospitalier Universitaire (CHU) de Nantes, l'institut du thorax, Service de Cardiologie, Nantes, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijcard.2016.01.052DOI Listing
March 2016

Fine-scale human genetic structure in Western France.

Eur J Hum Genet 2015 Jun 3;23(6):831-6. Epub 2014 Sep 3.

1] INSERM UMR 1087, Nantes, France [2] CNRS, UMR 6291 institut du thorax, Nantes, France [3] Université de Nantes, Nantes, France [4] CHU Nantes, l'institut du thorax, Service de Cardiologie, Nantes, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ejhg.2014.175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795055PMC
June 2015

Correlation of intracardiac electrogram with surface electrocardiogram in Brugada syndrome patients.

Europace 2014 Jun 25;16(6):908-13. Epub 2013 Sep 25.

Saint Jude Medical, 15900 Valley View Court Sylmar, CA 91342, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/eut294DOI Listing
June 2014

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.

Nat Genet 2013 Sep 21;45(9):1044-9. Epub 2013 Jul 21.

Department of Clinical and Experimental Cardiology, Heart Failure Research Center, Academic Medical Center, Amsterdam, The Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.2712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869788PMC
September 2013

Risk Stratification and Therapeutic Approach in Brugada Syndrome.

Arrhythm Electrophysiol Rev 2012 Sep;1(1):17-21

Professor of Cardiology and Head, Thorax Institute, Nantes, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15420/aer.2012.1.1.17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4711526PMC
September 2012

Copenhagen city heart study: more mermaids than Brugada's patients in Copenhagen.

Europace 2010 Jul 27;12(7):923-4. Epub 2010 May 27.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/euq143DOI Listing
July 2010

Response to intravenous ajmaline: a retrospective analysis of 677 ajmaline challenges.

Europace 2009 Oct 9;11(10):1345-52. Epub 2009 Jul 9.

11st Department of Medicine-Cardiology, University Hospital Mannheim, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/eup189DOI Listing
October 2009

Brugada syndrome: where are you?

Europace 2009 Oct;11(10):1260-1

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/europace/eup267DOI Listing
October 2009

Ajmaline challenge: to stop or not to stop...

Heart Rhythm 2009 May 11;6(5):632-3. Epub 2009 Mar 11.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hrthm.2009.03.009DOI Listing
May 2009

14-3-3 is a regulator of the cardiac voltage-gated sodium channel Nav1.5.

Circ Res 2006 Jun 25;98(12):1538-46. Epub 2006 May 25.

Inserm UMR533, Université de Nantes, Nantes Atlantique Universités, l'Institut du thorax, Faculté de Médecine, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.RES.0000229244.97497.2cDOI Listing
June 2006

Monomorphic ventricular tachycardia due to Brugada syndrome successfully treated by hydroquinidine therapy in a 3-year-old child.

J Cardiovasc Electrophysiol 2006 Jan;17(1):97-100

Department of Cardiology and Unité INSERM U533, Institut du thorax, CHU de Nantes, Nantes, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1540-8167.2005.00329.xDOI Listing
January 2006

A common antitussive drug, clobutinol, precipitates the long QT syndrome 2.

Mol Pharmacol 2004 Nov 27;66(5):1093-102. Epub 2004 Jul 27.

l'Institut du thorax, Institut National de la Sante et de la Recherche Medicale U533, Nantes, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1124/mol.104.001065DOI Listing
November 2004

[Prevention of cardiac arrhythmias: what is the place for antiarrhythmic drugs?].

Rev Prat 2004 Feb;54(3):286-90

Clinique cardiologique et des maladies vasculaires, CHU de Nantes-Hôpital G. et R. Laennec, 44093 Nantes Cedex 1.

View Article

Download full-text PDF

Source
February 2004

Cardiac retention of [11C]HED in genotyped long QT patients: a potential amplifier role for severity of the disease.

Am J Physiol Heart Circ Physiol 2003 Sep 29;285(3):H1286-93. Epub 2003 May 29.

Centre d'Exploration et de Recherche Médicales par Emission de Positons, 69003 Lyon, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpheart.00276.2003DOI Listing
September 2003

Na+ channel mutation leading to loss of function and non-progressive cardiac conduction defects.

J Mol Cell Cardiol 2003 May;35(5):549-57

Department of Medical Physiology, University Medical Center, Universiteitsweg 100, 3584CG, The, Utrecht, Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0022-2828(03)00078-6DOI Listing
May 2003

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death.

Nature 2003 Feb;421(6923):634-9

Howard Hughes Medical Institute and Departments of Cell Biology, Biochemistry, and Neuroscience, Duke University Medical Center, Durham, North Carolina 27710, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature01335DOI Listing
February 2003

Novel brugada SCN5A mutation leading to ST segment elevation in the inferior or the right precordial leads.

J Cardiovasc Electrophysiol 2003 Feb;14(2):200-3

Institut National de la Santé et de la Recherche Médicale (INSERM) U533, Faculté de Médecine, the Cardiology Department, Hôpital G&R Laennec, Nantes, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1046/j.1540-8167.2003.02382.xDOI Listing
February 2003