Hermann Einsele

Hermann Einsele

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Hermann Einsele

Hermann Einsele

Publications by authors named "Hermann Einsele"

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The BiTE (bispecific T-cell engager) platform: Development and future potential of a targeted immuno-oncology therapy across tumor types.

Cancer 2020 Jul 13;126(14):3192-3201. Epub 2020 May 13.

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1002/cncr.32909DOI Listing
July 2020

Inefficient CAR-proximal signaling blunts antigen sensitivity.

Nat Immunol 2020 Jul 6. Epub 2020 Jul 6.

Center for Pathophysiology, Infectiology and Immunology, Institute for Hygiene and Applied Immunology, Medical University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1038/s41590-020-0719-0DOI Listing
July 2020

[Recurrent Therapy of Multiple Myeloma - Individualized Concepts from The Arsenal of Diverse Options].

Dtsch Med Wochenschr 2020 Jun 17;145(12):820-827. Epub 2020 Jun 17.

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http://dx.doi.org/10.1055/a-1016-0384DOI Listing
June 2020

How I treat CMV reactivation after allogeneic hematopoietic stem cell transplantation.

Blood 2020 May;135(19):1619-1629

Vaccine and Infectious Disease Division and.

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http://dx.doi.org/10.1182/blood.2019000956DOI Listing
May 2020

Bispecific, T-Cell-Recruiting Antibodies in B-Cell Malignancies.

Front Immunol 2020 7;11:762. Epub 2020 May 7.

Laboratory of Hematology, GIGA I3, University of Liège, Liège, Belgium.

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http://dx.doi.org/10.3389/fimmu.2020.00762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221185PMC
May 2020

Donor-cell leukemia with novel genetic features 2 years after sex-mismatched T cell-depleted haploidentical stem cell transplantation.

Ann Hematol 2020 Apr 22;99(4):899-901. Epub 2020 Feb 22.

Department of Internal Medicine II, University Hospital of Würzburg, Oberdürrbacher Str. 6, D-97080, Würzburg, Germany.

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http://dx.doi.org/10.1007/s00277-020-03905-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7069896PMC
April 2020

β-.

J Immunother Cancer 2020 Apr;8(1)

Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Bayern, Germany.

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http://dx.doi.org/10.1136/jitc-2020-000676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7204619PMC
April 2020

The screening of blood by Aspergillus PCR and galactomannan ELISA precedes BAL detection in patients with proven and probable IA.

Med Mycol 2020 Mar 2. Epub 2020 Mar 2.

Public Health Wales Microbiology, Cardiff, United Kingdom.

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http://dx.doi.org/10.1093/mmy/myaa007DOI Listing
March 2020

Impact of immunosuppressive and antifungal drugs on PBMC- and whole blood-based flow cytometric CD154Aspergillus fumigatus specific T-cell quantification.

Med Microbiol Immunol 2020 Mar 31. Epub 2020 Mar 31.

Division of Infectious Diseases, Department of Internal Medicine II, University Hospital of Wuerzburg, Würzburg, Germany.

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http://dx.doi.org/10.1007/s00430-020-00665-3DOI Listing
March 2020

Development and evaluation of a whole blood-based approach for flow cytometric quantification of CD154+ mould-reactive T cells.

Med Mycol 2020 Feb;58(2):187-196

University Hospital of Wuerzburg, Department of Internal Medicine II, Division of Infectious Diseases, Josef-Schneider-Str. 2, 97080 Wuerzburg, Germany.

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http://dx.doi.org/10.1093/mmy/myz038DOI Listing
February 2020

Excretion of Ascaris lumbricoides following reduced-intensity allogeneic hematopoietic stem cell transplantation and consecutive treatment with mebendazole.

Transpl Infect Dis 2020 Feb 19;22(1):e13224. Epub 2020 Feb 19.

Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1111/tid.13224DOI Listing
February 2020

Response to daratumumab in rituximab-resistant EBV-associated PTLD following allogenic stem cell transplantation from an EBV seronegative donor.

Leuk Lymphoma 2019 12 18;60(14):3573-3576. Epub 2019 Jul 18.

Universitatsklinikum Wurzburg, Medizinische Klinik und Poliklinik II, Wurzburg, Germany.

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http://dx.doi.org/10.1080/10428194.2019.1636981DOI Listing
December 2019

A highly soluble Sleeping Beauty transposase improves control of gene insertion.

Nat Biotechnol 2019 12 4;37(12):1502-1512. Epub 2019 Nov 4.

Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41587-019-0291-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894935PMC
December 2019

Hereditary spherocytosis is associated with decreased pyruvate kinase activity due to impaired structural integrity of the red blood cell membrane.

Br J Haematol 2019 11 5;187(3):386-395. Epub 2019 Jul 5.

Department of Paediatrics, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1111/bjh.16084DOI Listing
November 2019

Detection of Species in Clinical Specimens by Probe-Based Real-Time PCR.

J Fungi (Basel) 2019 Nov 12;5(4). Epub 2019 Nov 12.

Department for Internal Medicine II, University Hospital of Wuerzburg, 97080 Wuerzburg, Germany.

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http://dx.doi.org/10.3390/jof5040105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6958410PMC
November 2019

CAR T Cells Beyond Cancer: Hope for Immunomodulatory Therapy of Infectious Diseases.

Front Immunol 2019 21;10:2711. Epub 2019 Nov 21.

Department of Internal Medicine II, University Hospital Wuerzburg, Würzburg, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.02711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881243PMC
November 2019

First Insights in NK-DC Cross-Talk and the Importance of Soluble Factors During Infection With .

Front Cell Infect Microbiol 2018 20;8:288. Epub 2018 Aug 20.

Department of Internal Medicine II, University Hospital Wuerzburg, WÜ4i, Wuerzburg, Germany.

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http://dx.doi.org/10.3389/fcimb.2018.00288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110135PMC
August 2019

The use of bispecific antibodies to optimize the outcome of patients with acute leukemia, lymphoma and multiple myeloma after SCT.

Bone Marrow Transplant 2019 08;54(Suppl 2):721-726

Department of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1038/s41409-019-0596-zDOI Listing
August 2019

The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR T cells.

Sci Transl Med 2019 07;11(499)

Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, 97080 Würzburg, Germany.

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http://dx.doi.org/10.1126/scitranslmed.aau5907DOI Listing
July 2019

Super-resolution microscopy reveals ultra-low CD19 expression on myeloma cells that triggers elimination by CD19 CAR-T.

Nat Commun 2019 07 17;10(1):3137. Epub 2019 Jul 17.

Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Oberdürrbacherstrasse 6, 97080, Würzburg, Germany.

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http://dx.doi.org/10.1038/s41467-019-10948-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6637169PMC
July 2019

Invasive Fungal Infection.

Dtsch Arztebl Int 2019 Apr;116(16):271-278

National Reference Center for Invasive Fungal Infections, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute (HKI), Jena; Clinic of Internal Medicine II, University Hospital Jena; Institute for Hygiene and Microbiology, University of Würzburg, Chair of Medical Microbiology and Mycology, Würzburg; Department of Internal Medicine II, University Hospital of Würzburg; InfectControl 2020, Jena/Würzburg; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Department I of Internal Medicine, at the University Hospital of Cologne, European Excellence Center for Medical Mycology (ECMM), DGerman Center for Infection Research(DZIF) Partner Site Bonn Köln, Cologne University.

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http://dx.doi.org/10.3238/arztebl.2019.0271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6549129PMC
April 2019

Hexokinase-2 Expression in C-Methionine-Positive, F-FDG-Negative Multiple Myeloma.

J Nucl Med 2019 03 2;60(3):348-352. Epub 2018 Nov 2.

Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany; and

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http://dx.doi.org/10.2967/jnumed.118.217539DOI Listing
March 2019

Clinical and biological characteristics of myeloma patients influence response to elotuzumab combination therapy.

J Cancer Res Clin Oncol 2019 Mar 5;145(3):561-571. Epub 2018 Dec 5.

Division of Hematology and Medical Oncology, Department of Internal Medicine II, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080, Würzburg, Germany.

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http://dx.doi.org/10.1007/s00432-018-2807-1DOI Listing
March 2019

Feasibility of CXCR4-Directed Radioligand Therapy in Advanced Diffuse Large B-Cell Lymphoma.

J Nucl Med 2019 01 18;60(1):60-64. Epub 2018 May 18.

Division of Hematology and Medical Oncology, Department of Internal Medicine II, Universitätsklinikum Würzburg, Würzburg, Germany; and.

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http://dx.doi.org/10.2967/jnumed.118.210997DOI Listing
January 2019

Role of Proteasome Inhibitors in Relapsed and/or Refractory Multiple Myeloma.

Clin Lymphoma Myeloma Leuk 2019 01 5;19(1):9-22. Epub 2018 Sep 5.

Department of Hematology, Mayo Clinic, Jacksonville, FL.

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https://linkinghub.elsevier.com/retrieve/pii/S21522650183061
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http://dx.doi.org/10.1016/j.clml.2018.08.016DOI Listing
January 2019

Author Correction: Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2019 01 10;10(1):213. Epub 2019 Jan 10.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-08107-8
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http://dx.doi.org/10.1038/s41467-018-08107-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328616PMC
January 2019

Evaluation of Aspergillus and Mucorales specific T-cells and peripheral blood mononuclear cell cytokine signatures as biomarkers of environmental mold exposure.

Int J Med Microbiol 2018 Dec 3;308(8):1018-1026. Epub 2018 Sep 3.

University Hospital of Wuerzburg, Department of Internal Medicine II, Division of Infectious Diseases, Josef-Schneider-Str. 2, 97080 Wuerzburg, Germany; The University of Texas MD Anderson Cancer Center, Department of Infectious Diseases, 1515 Holcombe Boulevard, Houston, Texas, 77030, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ijmm.2018.09.002DOI Listing
December 2018

Immunomodulation as a Therapy for Infection: Current Status and Future Perspectives.

J Fungi (Basel) 2018 Dec 14;4(4). Epub 2018 Dec 14.

Department of Internal Medicine II, University Hospital Wuerzburg, WÜ4i, Building C11, 97080 Wuerzburg, Germany.

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http://www.mdpi.com/2309-608X/4/4/137
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http://dx.doi.org/10.3390/jof4040137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6308942PMC
December 2018

Human NK cells adapt their immune response towards increasing multiplicities of infection of Aspergillus fumigatus.

BMC Immunol 2018 12 18;19(1):39. Epub 2018 Dec 18.

Department of Internal Medicine II, WÜ4i, University Hospital Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1186/s12865-018-0276-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299526PMC
December 2018

Navigating the changing multiple myeloma treatment landscape: clinical practice patterns of MM patients treated in- and outside German DSMM study group trials.

Leuk Lymphoma 2018 11 23;59(11):2692-2699. Epub 2018 Mar 23.

a Department of Hematology, Oncology, Stem Cell Transplantation , University Medical Center Freiburg , Freiburg , Germany.

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http://dx.doi.org/10.1080/10428194.2018.1448084DOI Listing
November 2018

Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma.

Nat Commun 2018 09 13;9(1):3707. Epub 2018 Sep 13.

Division of Genetics and Epidemiology, The Institute of Cancer Research, London, SW7 3RP, UK.

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http://www.nature.com/articles/s41467-018-04989-w
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http://dx.doi.org/10.1038/s41467-018-04989-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137048PMC
September 2018

CAR T cells targeting αβ integrin are effective against advanced cancer in preclinical models.

Adv Cell Gene Ther 2018 Sep 10;1(2). Epub 2018 Jul 10.

Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.

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http://doi.wiley.com/10.1002/acg2.11
Publisher Site
http://dx.doi.org/10.1002/acg2.11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226260PMC
September 2018

Susceptibility of A. fumigatus-specific T-cell assays to pre-analytic blood storage and PBMC cryopreservation greatly depends on readout platform and analytes.

Mycoses 2018 Aug 11;61(8):549-560. Epub 2018 Jun 11.

Division of Infectious Diseases, Department of Internal Medicine II, University Hospital of Wuerzburg, Wuerzburg, Germany.

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http://dx.doi.org/10.1111/myc.12780DOI Listing
August 2018