Hermann Einsele

Hermann Einsele

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Hermann Einsele

Hermann Einsele

Publications by authors named "Hermann Einsele"

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100Publications

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Evaluation of Aspergillus and Mucorales specific T-cells and peripheral blood mononuclear cell cytokine signatures as biomarkers of environmental mold exposure.

Int J Med Microbiol 2018 Dec 3;308(8):1018-1026. Epub 2018 Sep 3.

University Hospital of Wuerzburg, Department of Internal Medicine II, Division of Infectious Diseases, Josef-Schneider-Str. 2, 97080 Wuerzburg, Germany; The University of Texas MD Anderson Cancer Center, Department of Infectious Diseases, 1515 Holcombe Boulevard, Houston, Texas, 77030, United States. Electronic address:

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December 2018

Clinical and biological characteristics of myeloma patients influence response to elotuzumab combination therapy.

J Cancer Res Clin Oncol 2018 Dec 5. Epub 2018 Dec 5.

Division of Hematology and Medical Oncology, Department of Internal Medicine II, University Hospital Würzburg, Oberdürrbacherstraße 6, 97080, Würzburg, Germany.

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December 2018

Role of Proteasome Inhibitors in Relapsed and/or Refractory Multiple Myeloma.

Clin Lymphoma Myeloma Leuk 2018 Sep 5. Epub 2018 Sep 5.

Department of Hematology, Mayo Clinic, Jacksonville, FL.

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September 2018

CAR T cells targeting αβ integrin are effective against advanced cancer in preclinical models.

Adv Cell Gene Ther 2018 Sep 10;1(2). Epub 2018 Jul 10.

Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.

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September 2018

Susceptibility of A. fumigatus-specific T-cell assays to pre-analytic blood storage and PBMC cryopreservation greatly depends on readout platform and analytes.

Mycoses 2018 Aug 11;61(8):549-560. Epub 2018 Jun 11.

Division of Infectious Diseases, Department of Internal Medicine II, University Hospital of Wuerzburg, Wuerzburg, Germany.

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August 2018

Definitions of Resistant and Refractory Cytomegalovirus Infection and Disease in Transplant Recipients for Use in Clinical Trials.

Clin Infect Dis 2018 Aug 22. Epub 2018 Aug 22.

Department of Cellular Therapy and Allogeneic Stem Cell Transplantation, Karolinska University Hospital, Stockholm, Sweden; Division of Hematology, Department of Medicine, Huddinge, Karolinska Institutet, Stockholm, Sweden.

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August 2018

Antiviral prophylaxis for cytomegalovirus infection in allogeneic hematopoietic cell transplantation.

Blood Adv 2018 Aug;2(16):2159-2175

Department of Medical Oncology, Dana-Farber Cancer Institute, and.

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August 2018

First Insights in NK-DC Cross-Talk and the Importance of Soluble Factors During Infection With .

Front Cell Infect Microbiol 2018 20;8:288. Epub 2018 Aug 20.

Department of Internal Medicine II, University Hospital Wuerzburg, WÜ4i, Wuerzburg, Germany.

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August 2018

[ C]Methionine emerges as a new biomarker for tracking active myeloma lesions.

Br J Haematol 2018 Jun 3;181(5):701-703. Epub 2017 May 3.

Department of Haematology and Oncology, University Hospital Würzburg, Würzburg, Germany.

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June 2018

ECIL guidelines for the prevention, diagnosis and treatment of BK polyomavirus-associated haemorrhagic cystitis in haematopoietic stem cell transplant recipients.

J Antimicrob Chemother 2018 Jan;73(1):12-21

Transplantation & Clinical Virology, Department Biomedicine (Haus Petersplatz), University of Basel, Petersplatz 10; CH-4009 Basel, Switzerland.

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January 2018

Heterogeneity of Specific CD4+ and CD8+ T Cells Stimulated by CMV pp65 and IE1 Antigens.

J Immunother 2016 Nov/Dec;39(9):329-342

*Fondazione Progetto Ematologia (Hematology Project Foundation Research Laboratories) †Department of Cell Therapy and Hematology, San Bortolo Hospital, Vicenza, Italy ‡Department of Internal Medicine II, Division of Hematology and Oncology, Julius Maximilian University Medical Center, Würzburg, Germany.

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December 2017

SLAMF7-CAR T cells eliminate myeloma and confer selective fratricide of SLAMF7 normal lymphocytes.

Blood 2017 12 31;130(26):2838-2847. Epub 2017 Oct 31.

Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.

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December 2017

Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation.

N Engl J Med 2017 12 6;377(25):2433-2444. Epub 2017 Dec 6.

From the Dana-Farber Cancer Institute and Brigham and Women's Hospital (F.M.M.) and Tufts Medical Center and Tufts University School of Medicine (D.R.S.), Boston; Karolinska University Hospital and Karolinska Institutet, Stockholm (P.L.); University of Texas M.D. Anderson Cancer Center, Houston (R.F.C.); Universitaire Ziekenhuizen Leuven, Leuven, Belgium (J.M.); City of Hope National Medical Center, Duarte (S.S.D.), and Stanford University School of Medicine, Palo Alto (J.B.) - both in California; Hospital Universitario Puerta de Hierro-Majadahonda, Madrid (R.F.D.); Juravinski Hospital and Cancer Center, McMaster University, Hamilton, ON, Canada (S.H.); Universitätsklinikum Würzburg, Würzburg, Germany (A.J.U., H.E.); Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital, Hiroshima (Y. Katayama), and Saitama Medical Center, Jichi Medical University, Saitama (Y. Kanda) - both in Japan; University of Chicago, Chicago (K.M.M.); Fred Hutchinson Cancer Research Center, Seattle (M.B.); Perelman School of Medicine at the University of Pennsylvania, Philadelphia (E.A.B.); and Merck, Kenilworth, NJ (M.J.D., V.L.T., H.W., Y.M., N.A.K., R.Y.L., C.B.).

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December 2017

Mucorales spores induce a proinflammatory cytokine response in human mononuclear phagocytes and harbor no rodlet hydrophobins.

Virulence 2017 11 8;8(8):1708-1718. Epub 2017 Aug 8.

a Department of Internal Medicine II, Infectious Diseases , University Hospital of Würzburg , Würzburg , Germany.

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November 2017

Human leukocyte antigen-E mismatch is associated with better hematopoietic stem cell transplantation outcome in acute leukemia patients.

Haematologica 2017 11 7;102(11):1947-1955. Epub 2017 Sep 7.

Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Transfusion Service, Baden Wuerttemberg - Hessen, and University Hospital Ulm, Germany

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November 2017

First targeted therapy in multiple myeloma.

Blood 2017 11;130(22):2359-2360

UNIVERSITY HOSPITAL WÜRZBURG.

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November 2017

Intra- and inter-individual variability of Aspergillus fumigatus reactive T-cell frequencies in healthy volunteers in dependency of mould exposure in residential and working environment.

Mycoses 2017 Oct 8;60(10):668-675. Epub 2017 Aug 8.

Department of Internal Medicine II, Division of Infectious Diseases, University Hospital of Wuerzburg, Wuerzburg, Germany.

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October 2017

Impact of Donor Activating KIR Genes on HSCT Outcome in C1-Ligand Negative Myeloid Disease Patients Transplanted with Unrelated Donors-A Retrospective Study.

PLoS One 2017 20;12(1):e0169512. Epub 2017 Jan 20.

Institute of Clinical Transfusion Medicine and Immunogenetics Ulm, German Red Cross Blood Transfusion Service, Baden Wuerttenberg-Hessen and University Hospital of Ulm, Ulm, Germany.

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August 2017

Cytomegalovirus disease in hematopoietic stem cell transplant patients: current and future therapeutic options.

Curr Opin Infect Dis 2017 Aug;30(4):372-376

aDepartment of Hematology, Osaka International Cancer Institute, Osaka, Japan bDivision of Hematology/Oncology, Department of Internal Medicine II, University Hospital of Würzburg, Würzburg, Germany.

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August 2017

CD56 Is a Pathogen Recognition Receptor on Human Natural Killer Cells.

Sci Rep 2017 Jul 21;7(1):6138. Epub 2017 Jul 21.

Department of Internal Medicine II, WÜ4i, University Hospital Wuerzburg, Wuerzburg, Germany.

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July 2017

Panobinostat induces CD38 upregulation and augments the antimyeloma efficacy of daratumumab.

Blood 2017 06 5;129(25):3386-3388. Epub 2017 May 5.

Medizinische Klinik und Poliklinik II, Universitätsklinikum Würzburg, Würzburg, Germany.

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June 2017

Robust 8-color flow cytometry panel reveals enhanced effector function of NKG2C CD57 FcεRγ NK cells in CMV seropositive human blood donors.

Immunobiology 2017 05 25;222(5):719-725. Epub 2017 Jan 25.

Immune Recovery Section, Department of Internal Medicine II, Division of Hematology, University Hospital of Würzburg, Würzburg, Germany.

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May 2017

Dasatinib and allogeneic stem cell transplantation enable sustained response in an elderly patient with -positive acute lymphoblastic leukemia.

Haematologica 2017 04 5;102(4):e160-e162. Epub 2017 Jan 5.

Department of Internal Medicine and Hematology, Oncology and Immunology, Philipps University Marburg, and University Hospital Giessen and Marburg, Baldingerstrasse, Germany

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April 2017

Targeting of the WT1 fragment to human dendritic cells improves leukemia-specific T-cell responses providing an alternative approach to WT1-based vaccination.

Cancer Immunol Immunother 2017 Mar 28;66(3):319-332. Epub 2016 Nov 28.

Laboratory for Immunotherapy, Department of Internal Medicine II, University Hospital of Würzburg, Josef-Schneider-Str. 2, 97080, Würzburg, Germany.

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March 2017

Deacetylase inhibitors: an advance in myeloma therapy?

Expert Rev Hematol 2017 Mar 1;10(3):229-237. Epub 2017 Feb 1.

a Department of Hematologic Malignancies , Dana-Farber Cancer Institute , Boston , MA , USA.

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March 2017

Specific and Novel microRNAs Are Regulated as Response to Fungal Infection in Human Dendritic Cells.

Front Microbiol 2017 23;8:270. Epub 2017 Feb 23.

Systems Biology/Bioinformatics, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute Jena, Germany.

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February 2017

Silencing of CDK2, but not CDK1, separates mitogenic from anti-apoptotic signaling, sensitizing p53 defective cells for synthetic lethality.

Cell Cycle 2016 Dec 10;15(23):3203-3209. Epub 2016 Nov 10.

a Department of Internal Medicine II , Julius-Maximilians University , Wuerzburg , Germany.

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December 2016

Clinical evaluation of a Mucorales-specific real-time PCR assay in tissue and serum samples.

J Med Microbiol 2016 Dec 24;65(12):1414-1421. Epub 2016 Oct 24.

1​Department for Internal Medicine II, University Hospital of Wuerzburg, Wuerzburg, Germany.

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December 2016

Hsp90 inhibition ameliorates CD4 T cell-mediated acute Graft versus Host disease in mice.

Immun Inflamm Dis 2016 12 10;4(4):463-473. Epub 2016 Oct 10.

Institute for Virology and Immunobiology University of Würzburg Würzburg Germany.

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December 2016

Immunotherapy for opportunistic infections: Current status and future perspectives.

Virulence 2016 11 6;7(8):939-949. Epub 2016 Jul 6.

b Department of Internal Medicine II , Division of Hematology/Oncology, University Hospital of Würzburg , Würzburg , Germany.

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November 2016

Treatment of multiple myeloma with the immunostimulatory SLAMF7 antibody elotuzumab.

Ther Adv Hematol 2016 Oct 15;7(5):288-301. Epub 2016 Jul 15.

University Hospital Wuerzburg, Würzburg, Germany.

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October 2016

Pneumocystis jirovecii pneumonia: still a concern in patients with haematological malignancies and stem cell transplant recipients.

J Antimicrob Chemother 2016 09 12;71(9):2379-85. Epub 2016 May 12.

Department of Haematology, Acute Leukaemia and Stem Cell Transplantation Unit, University Hospitals Leuven, Campus Gasthuisberg, Leuven, Belgium.

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September 2016

ECIL guidelines for the diagnosis of Pneumocystis jirovecii pneumonia in patients with haematological malignancies and stem cell transplant recipients.

J Antimicrob Chemother 2016 09 12;71(9):2386-96. Epub 2016 May 12.

Parasitology-Mycology Laboratory, Groupe Hospitalier Lariboisière Saint-Louis Fernand Widal, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris-Diderot, Sorbonne Paris Cité, and Institut Pasteur, Unité de Mycologie Moléculaire, CNRS URA3012, Centre National de Référence Mycoses Invasives et Antifongiques, Paris, France.

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September 2016

ECIL guidelines for preventing Pneumocystis jirovecii pneumonia in patients with haematological malignancies and stem cell transplant recipients.

J Antimicrob Chemother 2016 09 12;71(9):2397-404. Epub 2016 May 12.

Department of Haematology, Henri Mondor Teaching Hospital, Assistance Publique-Hôpitaux de Paris, and Université Paris-Est-Créteil, Créteil, France

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September 2016

Myeloma CARs are rolling into the clinical arena.

Blood 2016 09;128(13):1667-8

UNIVERSITÄTSKLINIKUM WÜRZBURG.

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September 2016

Hypoxia attenuates anti-Aspergillus fumigatus immune responses initiated by human dendritic cells.

Mycoses 2016 Aug 23;59(8):503-8. Epub 2016 Mar 23.

Medical Clinic and Polyclinic II, University Hospital, Wuerzburg, Germany.

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August 2016

Common Genetic Polymorphisms within NFκB-Related Genes and the Risk of Developing Invasive Aspergillosis.

Front Microbiol 2016 12;7:1243. Epub 2016 Aug 12.

Genomic Oncology Area, GENYO, Center for Genomics and Oncological Research, Pfizer/University of Granada/Andalusian Regional Government, PTS GranadaGranada, Spain; Hematology Department, Virgen de las Nieves University HospitalGranada, Spain.

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August 2016

Impact of Donor Epstein-Barr Virus Serostatus on the Incidence of Graft-Versus-Host Disease in Patients With Acute Leukemia After Hematopoietic Stem-Cell Transplantation: A Study From the Acute Leukemia and Infectious Diseases Working Parties of the European Society for Blood and Marrow Transplantation.

J Clin Oncol 2016 07 18;34(19):2212-20. Epub 2016 Apr 18.

Jan Styczynski, Collegium Medicum, Nicolaus Copernicus University Torun, Bydgoszcz; Lidia Gil, Medical University, Poznan, Poland; Gloria Tridello and Simone Cesaro, Azienda Ospedaliera Universitaria Integrata, Verona; Simona Iacobelli, Università di Roma "Tor Vergata", Roma, Italy; Per Ljungman, Karolinska University Hospital, Stockholm, Sweden; Jennifer Hoek, European Bone Marrow Transplantation Group Data Office; Hendrik Veelken, Leiden University Medical Center, Leiden; Jan Cornelissen, Erasmus MC-Daniel den Hoed Cancer Centre, Rotterdam; Eefke Petersen, University Medical Centre, Utrecht, the Netherlands; Katherine N. Ward, University College London, London, United Kingdom; Catherine Cordonnier, Hôpital Henri Mondor, Assistance Publique-Hopitaux de Paris and Paris-Est-Créteil University, Creteil; Gerard Socie, Hopital St Louis; Mohamad Mohty, Saint Antoine Hospital, Paris, Institut National de la Santé et de la Recherche Médicale UMR 938, Paris; Noel Milpied, Centre Hospitalier Universitaire Bordeaux, Pessac; Patrice Chevallier, Centre Hospitalier Universitaire, Nantes; Ibrahim Yakoub-Agha, Centre Hospitalier Régional Universitaire, Lille; Didier Blaise, Centre de Recherche en Cancerologie, Marseille; Mauricette Michallet, Centre Hospitalier Lyon Sud, Pierre-Benite; Etienne Daguindau, Hopital Jean Minjoz, Besancon, France; Hermann Einsele, University Hospital, Wurzburg; Nicolaus Kröger, University Hospital Eppendorf, Hamburg; Peter Dreger, University of Heidelberg, Heidelberg, Germany; Johan Maertens, University Hospital Gasthuisberg, Leuven, Belgium; Jakob Passweg, University Hospital, Basel, Switzerland; Hildegard Greinix, Medical University of Graz, Graz, Austria; Rafael F. Duarte, Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain; and Arnon Nagler, Chaim Sheba Medical Center, Tel-Hashomer, Israel.

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July 2016

Dynamic Immune Cell Recruitment After Murine Pulmonary Aspergillus fumigatus Infection under Different Immunosuppressive Regimens.

Front Microbiol 2016 13;7:1107. Epub 2016 Jul 13.

Department of Medicine II, Würzburg University HospitalWürzburg, Germany; Research Center for Infectious Diseases, Julius-Maximilians-University WürzburgWürzburg, Germany; Interdisciplinary Center for Clinical Science Research LaboratoryWuürzburg, Germany; Graduate School of Life Sciences WürzburgWürzburg, Germany.

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July 2016

The Diagnosis and Treatment of Multiple Myeloma.

Dtsch Arztebl Int 2016 Jul;113(27-28):470-6

Department of Hematology, Oncology, Tumor Immunology, and Palliative Medicine, Helios Hospital Berlin- Buch, Berlin, Department of Medicine II, Würzburg University Hospital, Würzburg.

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July 2016