Publications by authors named "Herman H W Silljé"

81Publications

A combined bioinformatics, experimental and clinical approach to identify novel cardiac-specific heart failure biomarkers: is Dickkopf-3 (DKK3) a possible candidate?

Eur J Heart Fail 2020 Aug 18. Epub 2020 Aug 18.

Department of Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, the Netherlands.

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http://dx.doi.org/10.1002/ejhf.1988DOI Listing
August 2020

Correction to: Factor Xa Inhibition with Apixaban Does Not Influence Cardiac Remodelling in Rats with Heart Failure After Myocardial Infarction.

Cardiovasc Drugs Ther 2020 Jul 1. Epub 2020 Jul 1.

Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30.001, Groningen, 9700, RB, The Netherlands.

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http://dx.doi.org/10.1007/s10557-020-07029-2DOI Listing
July 2020

Quantification of Biventricular Function and Morphology by Cardiac Magnetic Resonance Imaging in Mice with Pulmonary Artery Banding.

J Vis Exp 2020 05 13(159). Epub 2020 May 13.

Center for Congenital Heart Diseases, Department of Pediatric Cardiology, University Medical Center Groningen, University of Groningen.

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http://dx.doi.org/10.3791/60837DOI Listing
May 2020

Factor Xa Inhibition with Apixaban Does Not Influence Cardiac Remodelling in Rats with Heart Failure After Myocardial Infarction.

Cardiovasc Drugs Ther 2020 May 26. Epub 2020 May 26.

Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30.001, Groningen, 9700 RB, The Netherlands.

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http://dx.doi.org/10.1007/s10557-020-06999-7DOI Listing
May 2020

Sodium-glucose co-transporter 2 inhibition as a mitochondrial therapy for atrial fibrillation in patients with diabetes?

Cardiovasc Diabetol 2020 01 7;19(1). Epub 2020 Jan 7.

Department of Cardiology, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/s12933-019-0984-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945755PMC
January 2020

Metabolic Remodeling in the Pressure-Loaded Right Ventricle: Shifts in Glucose and Fatty Acid Metabolism-A Systematic Review and Meta-Analysis.

J Am Heart Assoc 2019 11 28;8(21):e012086. Epub 2019 Oct 28.

Department of Pediatric Cardiology University Medical Center Groningen Center for Congenital Heart Diseases University of Groningen The Netherlands.

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http://dx.doi.org/10.1161/JAHA.119.012086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6898858PMC
November 2019

Current understanding of fibrosis in genetic cardiomyopathies.

Trends Cardiovasc Med 2020 08 23;30(6):353-361. Epub 2019 Sep 23.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, 9713 AV Groningen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.tcm.2019.09.003DOI Listing
August 2020

A novel method optimizing the normalization of cardiac parameters in small animal models: the importance of dimensional indexing.

Am J Physiol Heart Circ Physiol 2019 06 12;316(6):H1552-H1557. Epub 2019 Apr 12.

Center for Congenital Heart Diseases, Beatrix Children's Hospital, University Medical Center Groningen, University of Groningen , Groningen , The Netherlands.

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https://www.physiology.org/doi/10.1152/ajpheart.00182.2019
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http://dx.doi.org/10.1152/ajpheart.00182.2019DOI Listing
June 2019

The vicious cycle of arrhythmia and myocardial fibrosis.

Eur J Heart Fail 2019 04 30;21(4):492-494. Epub 2019 Jan 30.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/ejhf.1421DOI Listing
April 2019

Plasma levels of heart failure biomarkers are primarily a reflection of extracardiac production.

Theranostics 2018 30;8(15):4155-4169. Epub 2018 Jul 30.

Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands.

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http://dx.doi.org/10.7150/thno.26055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6096401PMC
September 2019

Novel heart failure biomarkers: why do we fail to exploit their potential?

Crit Rev Clin Lab Sci 2018 06 17;55(4):246-263. Epub 2018 Apr 17.

a Department of Cardiology , University Medical Center Groningen, University of Groningen , Groningen , The Netherlands.

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http://dx.doi.org/10.1080/10408363.2018.1460576DOI Listing
June 2018

Galectin-3 Activation and Inhibition in Heart Failure and Cardiovascular Disease: An Update.

Theranostics 2018 1;8(3):593-609. Epub 2018 Jan 1.

University Medical Center Groningen, University of Groningen, Department of Cardiology, PO Box 30.001, 9700 RB Groningen, the Netherlands.

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http://dx.doi.org/10.7150/thno.22196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771079PMC
December 2018

Mutations in Causing a Novel Orthostatic Hypotension Syndrome.

Circ Res 2018 03 17;122(6):846-854. Epub 2018 Jan 17.

From the Department of Cardiology (M.P.v.d.B., P.v.d.H., H.H.W.S., I.M.L.), Laboratory Medicine (M.v.F., I.P.K.), Department of Nephrology (G.N.), Department of Neurology (G.J.L.), and Department of Genetics (P.A.v.d.Z., J.D.H.J.), University Medical Center Groningen, University of Groningen, The Netherlands; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, Jordan University of Science and Technology, Irbid (R.A.); Division of Clinical Pharmacology, Vanderbilt University, Medical Center, Nashville, TN (I.B.); Department of Internal Medicine, Medical Center Leeuwarden, The Netherlands (M.H.H.); Department of Genetics (A.P.M.d.B.), Centre for Molecular and Biomolecular Informatics (H.V.), and Translational Metabolic Laboratory, Department of Laboratory Medicine (M.M.V., R.A.W.), Radboud University Medical Center Nijmegen, The Netherlands; and Department of Genetics, Academic Medical Center, University of Amsterdam, The Netherlands (J.P.v.T.).

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.117.31194
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http://dx.doi.org/10.1161/CIRCRESAHA.117.311949DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924476PMC
March 2018

Volume load-induced right ventricular dysfunction in animal models: insights in a translational gap in congenital heart disease.

Eur J Heart Fail 2018 04 18;20(4):808-812. Epub 2017 Sep 18.

Center for Congenital Heart Diseases, Department of Pediatric Cardiology, University of Groningen, University Medical Center Groningen, The Netherlands.

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http://dx.doi.org/10.1002/ejhf.931DOI Listing
April 2018

From Inflammation to Fibrosis-Molecular and Cellular Mechanisms of Myocardial Tissue Remodelling and Perspectives on Differential Treatment Opportunities.

Curr Heart Fail Rep 2017 08;14(4):235-250

Department of Cardiology, University Medical Center Groningen, University of Groningen, PO Box 30.001, 9700 RB, Groningen, The Netherlands.

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http://link.springer.com/10.1007/s11897-017-0343-y
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http://dx.doi.org/10.1007/s11897-017-0343-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5527069PMC
August 2017

Heart failure: Macrophages take centre stage in the heart-brain-kidney axis.

Nat Rev Nephrol 2017 07 30;13(7):388-390. Epub 2017 May 30.

University Medical Center Groningen, University of Groningen, Department of Cardiology, PO Box 30.001, 9700 RB, Groningen, Netherlands.

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http://dx.doi.org/10.1038/nrneph.2017.73DOI Listing
July 2017

52 Genetic Loci Influencing Myocardial Mass.

Authors:
Pim van der Harst Jessica van Setten Niek Verweij Georg Vogler Lude Franke Matthew T Maurano Xinchen Wang Irene Mateo Leach Mark Eijgelsheim Nona Sotoodehnia Caroline Hayward Rossella Sorice Osorio Meirelles Leo-Pekka Lyytikäinen Ozren Polašek Toshiko Tanaka Dan E Arking Sheila Ulivi Stella Trompet Martina Müller-Nurasyid Albert V Smith Marcus Dörr Kathleen F Kerr Jared W Magnani Fabiola Del Greco M Weihua Zhang Ilja M Nolte Claudia T Silva Sandosh Padmanabhan Vinicius Tragante Tõnu Esko Gonçalo R Abecasis Michiel E Adriaens Karl Andersen Phil Barnett Joshua C Bis Rolf Bodmer Brendan M Buckley Harry Campbell Megan V Cannon Aravinda Chakravarti Lin Y Chen Alessandro Delitala Richard B Devereux Pieter A Doevendans Anna F Dominiczak Luigi Ferrucci Ian Ford Christian Gieger Tamara B Harris Eric Haugen Matthias Heinig Dena G Hernandez Hans L Hillege Joel N Hirschhorn Albert Hofman Norbert Hubner Shih-Jen Hwang Annamaria Iorio Mika Kähönen Manolis Kellis Ivana Kolcic Ishminder K Kooner Jaspal S Kooner Jan A Kors Edward G Lakatta Kasper Lage Lenore J Launer Daniel Levy Alicia Lundby Peter W Macfarlane Dalit May Thomas Meitinger Andres Metspalu Stefania Nappo Silvia Naitza Shane Neph Alex S Nord Teresa Nutile Peter M Okin Jesper V Olsen Ben A Oostra Josef M Penninger Len A Pennacchio Tune H Pers Siegfried Perz Annette Peters Yigal M Pinto Arne Pfeufer Maria Grazia Pilia Peter P Pramstaller Bram P Prins Olli T Raitakari Soumya Raychaudhuri Ken M Rice Elizabeth J Rossin Jerome I Rotter Sebastian Schafer David Schlessinger Carsten O Schmidt Jobanpreet Sehmi Herman H W Silljé Gianfranco Sinagra Moritz F Sinner Kamil Slowikowski Elsayed Z Soliman Timothy D Spector Wilko Spiering John A Stamatoyannopoulos Ronald P Stolk Konstantin Strauch Sian-Tsung Tan Kirill V Tarasov Bosco Trinh Andre G Uitterlinden Malou van den Boogaard Cornelia M van Duijn Wiek H van Gilst Jorma S Viikari Peter M Visscher Veronique Vitart Uwe Völker Melanie Waldenberger Christian X Weichenberger Harm-Jan Westra Cisca Wijmenga Bruce H Wolffenbuttel Jian Yang Connie R Bezzina Patricia B Munroe Harold Snieder Alan F Wright Igor Rudan Laurie A Boyer Folkert W Asselbergs Dirk J van Veldhuisen Bruno H Stricker Bruce M Psaty Marina Ciullo Serena Sanna Terho Lehtimäki James F Wilson Stefania Bandinelli Alvaro Alonso Paolo Gasparini J Wouter Jukema Stefan Kääb Vilmundur Gudnason Stephan B Felix Susan R Heckbert Rudolf A de Boer Christopher Newton-Cheh Andrew A Hicks John C Chambers Yalda Jamshidi Axel Visel Vincent M Christoffels Aaron Isaacs Nilesh J Samani Paul I W de Bakker

J Am Coll Cardiol 2016 09;68(13):1435-1448

Department of Medical Genetics, University Medical Center Utrecht, Utrecht, the Netherlands; Department of Epidemiology, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.jacc.2016.07.729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5478167PMC
September 2016

In EXOG-depleted cardiomyocytes cell death is marked by a decreased mitochondrial reserve capacity of the electron transport chain.

Bioessays 2016 07;38 Suppl 1:S136-45

Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/bies.201670914DOI Listing
July 2016

Overexpression of A kinase interacting protein 1 attenuates myocardial ischaemia/reperfusion injury but does not influence heart failure development.

Cardiovasc Res 2016 08 14;111(3):217-26. Epub 2016 Jun 14.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Experimental Cardiology Section HPC AB 43, PO Box 30.001, Groningen 9700 RB, The Netherlands

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http://dx.doi.org/10.1093/cvr/cvw161DOI Listing
August 2016

HE4 Serum Levels Are Associated with Heart Failure Severity in Patients With Chronic Heart Failure.

J Card Fail 2017 Jan 17;23(1):12-19. Epub 2016 May 17.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cardfail.2016.05.002DOI Listing
January 2017

Hypertrophy induced KIF5B controls mitochondrial localization and function in neonatal rat cardiomyocytes.

J Mol Cell Cardiol 2016 08 17;97:70-81. Epub 2016 Apr 17.

Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2016.04.005DOI Listing
August 2016

LXRα improves myocardial glucose tolerance and reduces cardiac hypertrophy in a mouse model of obesity-induced type 2 diabetes.

Diabetologia 2016 Mar 18;59(3):634-43. Epub 2015 Dec 18.

University of Groningen, University Medical Center Groningen, Department of Cardiology, Hanzeplein 1, 9713 GZ, Groningen, the Netherlands.

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http://dx.doi.org/10.1007/s00125-015-3827-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742491PMC
March 2016

The liver X receptor agonist AZ876 protects against pathological cardiac hypertrophy and fibrosis without lipogenic side effects.

Eur J Heart Fail 2015 Mar 11;17(3):273-82. Epub 2015 Feb 11.

University Medical Center Groningen, University of Groningen, Department of Cardiology, Groningen, The Netherlands.

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http://dx.doi.org/10.1002/ejhf.243DOI Listing
March 2015

Clinical symptoms of right ventricular failure in experimental chronic pressure load are associated with progressive diastolic dysfunction.

J Mol Cell Cardiol 2015 Feb 5;79:244-53. Epub 2014 Dec 5.

Center for Congenital Heart Diseases, Department of Pediatric Cardiology, Beatrix Children's Hospital, The Netherlands; Cardiovascular Center-laboratory for Experimental Cardiology, Graduate School of Medical Sciences, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00222828140038
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http://dx.doi.org/10.1016/j.yjmcc.2014.11.024DOI Listing
February 2015

Loss of mitochondrial exo/endonuclease EXOG affects mitochondrial respiration and induces ROS-mediated cardiomyocyte hypertrophy.

Am J Physiol Cell Physiol 2015 Jan 5;308(2):C155-63. Epub 2014 Nov 5.

University Medical Center Groningen, University of Groningen, Department of Cardiology, Groningen, The Netherlands; and

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http://dx.doi.org/10.1152/ajpcell.00227.2014DOI Listing
January 2015

The WAP four-disulfide core domain protein HE4: a novel biomarker for heart failure.

JACC Heart Fail 2013 Apr 1;1(2):164-9. Epub 2013 Apr 1.

Department of Cardiology, University Medical Center Groningen, University of Groningen, the Netherlands.

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http://dx.doi.org/10.1016/j.jchf.2012.11.005DOI Listing
April 2013

AKIP1 expression modulates mitochondrial function in rat neonatal cardiomyocytes.

PLoS One 2013 13;8(11):e80815. Epub 2013 Nov 13.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands ; Department of Hematology, the First Affiliated Hospital of Harbin Medical University, Harbin, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0080815PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827472PMC
July 2014

AKIP1, a cardiac hypertrophy induced protein that stimulates cardiomyocyte growth via the Akt pathway.

Int J Mol Sci 2013 Oct 28;14(11):21378-93. Epub 2013 Oct 28.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, P.O. Box 30.001, Groningen 9700 RB, The Netherlands.

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http://dx.doi.org/10.3390/ijms141121378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3856010PMC
October 2013

Seventy-five genetic loci influencing the human red blood cell.

Authors:
Pim van der Harst Weihua Zhang Irene Mateo Leach Augusto Rendon Niek Verweij Joban Sehmi Dirk S Paul Ulrich Elling Hooman Allayee Xinzhong Li Aparna Radhakrishnan Sian-Tsung Tan Katrin Voss Christian X Weichenberger Cornelis A Albers Abtehale Al-Hussani Folkert W Asselbergs Marina Ciullo Fabrice Danjou Christian Dina Tõnu Esko David M Evans Lude Franke Martin Gögele Jaana Hartiala Micha Hersch Hilma Holm Jouke-Jan Hottenga Stavroula Kanoni Marcus E Kleber Vasiliki Lagou Claudia Langenberg Lorna M Lopez Leo-Pekka Lyytikäinen Olle Melander Federico Murgia Ilja M Nolte Paul F O'Reilly Sandosh Padmanabhan Afshin Parsa Nicola Pirastu Eleonora Porcu Laura Portas Inga Prokopenko Janina S Ried So-Youn Shin Clara S Tang Alexander Teumer Michela Traglia Sheila Ulivi Harm-Jan Westra Jian Yang Jing Hua Zhao Franco Anni Abdel Abdellaoui Antony Attwood Beverley Balkau Stefania Bandinelli François Bastardot Beben Benyamin Bernhard O Boehm William O Cookson Debashish Das Paul I W de Bakker Rudolf A de Boer Eco J C de Geus Marleen H de Moor Maria Dimitriou Francisco S Domingues Angela Döring Gunnar Engström Gudmundur Ingi Eyjolfsson Luigi Ferrucci Krista Fischer Renzo Galanello Stephen F Garner Bernd Genser Quince D Gibson Giorgia Girotto Daniel Fannar Gudbjartsson Sarah E Harris Anna-Liisa Hartikainen Claire E Hastie Bo Hedblad Thomas Illig Jennifer Jolley Mika Kähönen Ido P Kema John P Kemp Liming Liang Heather Lloyd-Jones Ruth J F Loos Stuart Meacham Sarah E Medland Christa Meisinger Yasin Memari Evelin Mihailov Kathy Miller Miriam F Moffatt Matthias Nauck Maria Novatchkova Teresa Nutile Isleifur Olafsson Pall T Onundarson Debora Parracciani Brenda W Penninx Lucia Perseu Antonio Piga Giorgio Pistis Anneli Pouta Ursula Puc Olli Raitakari Susan M Ring Antonietta Robino Daniela Ruggiero Aimo Ruokonen Aude Saint-Pierre Cinzia Sala Andres Salumets Jennifer Sambrook Hein Schepers Carsten Oliver Schmidt Herman H W Silljé Rob Sladek Johannes H Smit John M Starr Jonathan Stephens Patrick Sulem Toshiko Tanaka Unnur Thorsteinsdottir Vinicius Tragante Wiek H van Gilst L Joost van Pelt Dirk J van Veldhuisen Uwe Völker John B Whitfield Gonneke Willemsen Bernhard R Winkelmann Gerald Wirnsberger Ale Algra Francesco Cucca Adamo Pio d'Adamo John Danesh Ian J Deary Anna F Dominiczak Paul Elliott Paolo Fortina Philippe Froguel Paolo Gasparini Andreas Greinacher Stanley L Hazen Marjo-Riitta Jarvelin Kay Tee Khaw Terho Lehtimäki Winfried Maerz Nicholas G Martin Andres Metspalu Braxton D Mitchell Grant W Montgomery Carmel Moore Gerjan Navis Mario Pirastu Peter P Pramstaller Ramiro Ramirez-Solis Eric Schadt James Scott Alan R Shuldiner George Davey Smith J Gustav Smith Harold Snieder Rossella Sorice Tim D Spector Kari Stefansson Michael Stumvoll W H Wilson Tang Daniela Toniolo Anke Tönjes Peter M Visscher Peter Vollenweider Nicholas J Wareham Bruce H R Wolffenbuttel Dorret I Boomsma Jacques S Beckmann George V Dedoussis Panos Deloukas Manuel A Ferreira Serena Sanna Manuela Uda Andrew A Hicks Josef Martin Penninger Christian Gieger Jaspal S Kooner Willem H Ouwehand Nicole Soranzo John C Chambers

Nature 2012 Dec 5;492(7429):369-75. Epub 2012 Dec 5.

Department of Cardiology, University of Groningen, University Medical Center Groningen, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1038/nature11677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3623669PMC
December 2012

The vitamin D receptor activator paricalcitol prevents fibrosis and diastolic dysfunction in a murine model of pressure overload.

J Steroid Biochem Mol Biol 2012 Nov 16;132(3-5):282-9. Epub 2012 Jul 16.

Department of Cardiology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, Postal code AB43, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jsbmb.2012.06.004DOI Listing
November 2012

Sildenafil enhances systolic adaptation, but does not prevent diastolic dysfunction, in the pressure-loaded right ventricle.

Eur J Heart Fail 2012 Sep 22;14(9):1067-74. Epub 2012 Jun 22.

Center for Congenital Heart Diseases, Division of Pediatric Cardiology, Beatrix Children's Hospital, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, The Netherlands.

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http://dx.doi.org/10.1093/eurjhf/hfs094DOI Listing
September 2012

Identification of hypertrophy- and heart failure-associated genes by combining in vitro and in vivo models.

Physiol Genomics 2012 Apr 21;44(8):443-54. Epub 2012 Feb 21.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1152/physiolgenomics.00148.2011DOI Listing
April 2012

Direct regulation of tRNA and 5S rRNA gene transcription by Polo-like kinase 1.

Mol Cell 2012 Feb 25;45(4):541-52. Epub 2012 Jan 25.

Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK.

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http://dx.doi.org/10.1016/j.molcel.2011.11.030DOI Listing
February 2012

DHRS7c, a novel cardiomyocyte-expressed gene that is down-regulated by adrenergic stimulation and in heart failure.

Eur J Heart Fail 2012 Jan 4;14(1):5-13. Epub 2011 Dec 4.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1093/eurjhf/hfr152DOI Listing
January 2012

Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of post-myocardial infarction heart failure.

Cardiovasc Diabetol 2011 Sep 28;10:85. Epub 2011 Sep 28.

University Medical Center Groningen, University of Groningen, Department of Cardiology, Groningen, The Netherlands.

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http://dx.doi.org/10.1186/1475-2840-10-85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198901PMC
September 2011

Regulation of the (pro)renin-renin receptor in cardiac remodelling.

J Cell Mol Med 2012 Apr;16(4):722-9

University Medical Center Groningen, Thorax Center, Department of Cardiology, University of Groningen, The Netherlands.

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http://doi.wiley.com/10.1111/j.1582-4934.2011.01377.x
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http://dx.doi.org/10.1111/j.1582-4934.2011.01377.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3822843PMC
April 2012

Metformin improves cardiac function in a nondiabetic rat model of post-MI heart failure.

Am J Physiol Heart Circ Physiol 2011 Aug 13;301(2):H459-68. Epub 2011 May 13.

University Medical Center Groningen, Thorax Center, Department of Cardiology, University of Groningen, The Netherlands.

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http://dx.doi.org/10.1152/ajpheart.00054.2011DOI Listing
August 2011

Vitamin D status and outcomes in heart failure patients.

Eur J Heart Fail 2011 Jun 4;13(6):619-25. Epub 2011 May 4.

Department of Cardiology, University Medical Center Groningen, University of Groningen, The Netherlands.

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http://dx.doi.org/10.1093/eurjhf/hfr032DOI Listing
June 2011

Heart failure-associated anemia: bone marrow dysfunction and response to erythropoietin.

J Mol Med (Berl) 2011 Apr 30;89(4):377-87. Epub 2010 Dec 30.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands.

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http://dx.doi.org/10.1007/s00109-010-0710-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3056002PMC
April 2011

The Plk1 inhibitor BI 2536 temporarily arrests primary cardiac fibroblasts in mitosis and generates aneuploidy in vitro.

PLoS One 2010 Sep 24;5(9):e12963. Epub 2010 Sep 24.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012963PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945759PMC
September 2010

The Plk1-dependent phosphoproteome of the early mitotic spindle.

Mol Cell Proteomics 2011 Jan 22;10(1):M110.004457. Epub 2010 Sep 22.

Department of Cell Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1074/mcp.M110.004457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013462PMC
January 2011

Activation of liver X receptors with T0901317 attenuates cardiac hypertrophy in vivo.

Eur J Heart Fail 2010 Oct 29;12(10):1042-50. Epub 2010 Jun 29.

Department of Experimental Cardiology, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1093/eurjhf/hfq109DOI Listing
October 2010

Glucagon-like peptide 1 prevents reactive oxygen species-induced endothelial cell senescence through the activation of protein kinase A.

Arterioscler Thromb Vasc Biol 2010 Jul 6;30(7):1407-14. Epub 2010 May 6.

Department of Cardiology, University Medical Center Groningen, University of Groningen, Antonius Deusinglaan 1, 9713AV Groningen, the Netherlands.

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http://dx.doi.org/10.1161/ATVBAHA.110.206425DOI Listing
July 2010

Myostatin: an overlooked player in heart failure?

Eur J Heart Fail 2010 May 27;12(5):420-2. Epub 2010 Mar 27.

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http://dx.doi.org/10.1093/eurjhf/hfq044DOI Listing
May 2010

Plk1 regulates mitotic Aurora A function through betaTrCP-dependent degradation of hBora.

Chromosoma 2008 Oct 3;117(5):457-69. Epub 2008 Jun 3.

Department of Cell Biology, Max Planck Institute of Biochemistry, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1007/s00412-008-0165-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921497PMC
October 2008

The spindle protein CHICA mediates localization of the chromokinesin Kid to the mitotic spindle.

Curr Biol 2008 May;18(10):723-729

Department of Cell Biology, Max-Planck Institute of Biochemistry, Martinsried 82152, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2008.04.041DOI Listing
May 2008

Timely anaphase onset requires a novel spindle and kinetochore complex comprising Ska1 and Ska2.

EMBO J 2006 Nov 9;25(23):5504-15. Epub 2006 Nov 9.

Department of Cell Biology, Max-Planck-Institute for Biochemistry, Martinsried, Germany.

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http://dx.doi.org/10.1038/sj.emboj.7601426DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1679759PMC
November 2006

Influence of human Ect2 depletion and overexpression on cleavage furrow formation and abscission.

J Cell Sci 2006 Jul 27;119(Pt 14):3008-19. Epub 2006 Jun 27.

Max Planck Institute for Biochemistry, Department of Cell Biology, Am Klopferspitz 18, 82152 Martinsried, Germany.

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http://dx.doi.org/10.1242/jcs.03032DOI Listing
July 2006

HURP is a Ran-importin beta-regulated protein that stabilizes kinetochore microtubules in the vicinity of chromosomes.

Curr Biol 2006 Apr;16(8):731-42

Department of Cell Biology, Max Planck Institute of Biochemistry, Martinsried, Germany.

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http://dx.doi.org/10.1016/j.cub.2006.02.070DOI Listing
April 2006

Phosphoproteome analysis of the human mitotic spindle.

Proc Natl Acad Sci U S A 2006 Apr 24;103(14):5391-6. Epub 2006 Mar 24.

Department of Cell Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany.

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http://dx.doi.org/10.1073/pnas.0507066103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1459365PMC
April 2006

Purification of mitotic spindles from cultured human cells.

Methods 2006 Jan;38(1):25-8

Max Planck Institute of Biochemistry, Department of Cell Biology, Am Klopferspitz 18, D-82152 Martinsried, Germany.

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http://dx.doi.org/10.1016/j.ymeth.2005.07.006DOI Listing
January 2006

Different Plk1 functions show distinct dependencies on Polo-Box domain-mediated targeting.

Mol Biol Cell 2006 Jan 2;17(1):448-59. Epub 2005 Nov 2.

Department of Cell Biology, Max Planck Institute for Biochemistry, D-82152 Martinsried, Germany.

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http://dx.doi.org/10.1091/mbc.e05-08-0801DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1345681PMC
January 2006

The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1.

Oncogene 2005 Mar;24(12):2076-86

Department of Cell Biology, Max Planck Institute for Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany.

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http://dx.doi.org/10.1038/sj.onc.1208445DOI Listing
March 2005

Proteome analysis of the human mitotic spindle.

Mol Cell Proteomics 2005 Jan 23;4(1):35-43. Epub 2004 Nov 23.

Max Planck Institute of Biochemistry, Department of Cell Biology, D-82152 Martinsried, Germany.

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http://dx.doi.org/10.1074/mcp.M400158-MCP200DOI Listing
January 2005

Polo-like kinases and the orchestration of cell division.

Nat Rev Mol Cell Biol 2004 Jun;5(6):429-40

Department of Cell Biology, Max-Planck Institute of Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany.

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http://www.nature.com/articles/nrm1401
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June 2004

Regulation of Aurora-A kinase on the mitotic spindle.

Chromosoma 2003 Dec 21;112(4):159-63. Epub 2003 Nov 21.

Max Planck Institute for Biochemistry, Department of Cell Biology, Am Klopferspitz 18, 82152 Martinsried, Germany.

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http://link.springer.com/10.1007/s00412-003-0265-1
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December 2003

Tousled-like kinase functions with the chromatin assembly pathway regulating nuclear divisions.

Genes Dev 2003 Oct;17(20):2578-90

Abteilung Molekulare Entwicklungsbiologie, Max-Planck-Institut für biophysikalische Chemie, Am Fassberg, D-37077 Göttingen, Germany.

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http://dx.doi.org/10.1101/gad.276703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC218151PMC
October 2003

Suppression of Tousled-like kinase activity after DNA damage or replication block requires ATM, NBS1 and Chk1.

Oncogene 2003 Sep;22(38):5927-37

Signal Transduction Lab, Cancer and Cell Biology Division, Queensland Institute of Medical Research, 300 Herston Rd, Qld 4029, Australia.

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http://www.nature.com/articles/1206691
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September 2003

Signal transduction. Capturing polo kinase.

Science 2003 Feb;299(5610):1190-1

Department of Cell Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18a, D-82152 Martinsried, Germany.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1082384
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February 2003

Human TPX2 is required for targeting Aurora-A kinase to the spindle.

J Cell Biol 2002 Aug 12;158(4):617-23. Epub 2002 Aug 12.

Department of Cell Biology, Max Planck Institute of Biochemistry, Am Klopferspitz 18a, D-82152 Martinsried, Germany.

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http://dx.doi.org/10.1083/jcb.200204155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2174010PMC
August 2002

Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplication.

EMBO J 2002 Apr;21(7):1723-32

Max-Planck Institute for Biochemistry, Department of Cell Biology, Am Klopferspitz 18a, D-82152 Martinsried, Germany.

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http://dx.doi.org/10.1093/emboj/21.7.1723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC125937PMC
April 2002

Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway.

EMBO Rep 2002 Apr 15;3(4):329-34. Epub 2002 Mar 15.

Institut Curie, Research Section, UMR 218 du Centre National de la Recherche Scientifique (CNRS), 26 rue d'Ulm, 75248 Paris cedex 05, France.

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http://dx.doi.org/10.1093/embo-reports/kvf068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1084056PMC
April 2002