Herbert Y Lin

Herbert Y Lin

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Herbert Y Lin

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Fluid assessment in dialysis patients by point-of-care magnetic relaxometry.

Sci Transl Med 2019 Jul;11(502)

Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.

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http://dx.doi.org/10.1126/scitranslmed.aau1749DOI Listing
July 2019

Betaglycan (TGFBR3) Functions as an Inhibin A, but Not Inhibin B, Coreceptor in Pituitary Gonadotrope Cells in Mice.

Endocrinology 2018 12;159(12):4077-4091

Program in Membrane Biology/Nephrology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts.

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https://academic.oup.com/endo/advance-article/doi/10.1210/en
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http://dx.doi.org/10.1210/en.2018-00770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6372943PMC
December 2018

Repulsive guidance molecule b inhibits renal cyst development through the bone morphogenetic protein signaling pathway.

Cell Signal 2016 12 26;28(12):1842-1851. Epub 2016 Aug 26.

State Key Laboratory of Natural and Biomimetic Drugs, Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing, 100191, China. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2016.08.015DOI Listing
December 2016

Repulsive Guidance Molecule b (RGMb) Is Dispensable for Normal Gonadal Function in Mice.

Biol Reprod 2016 Apr 24;94(4):78. Epub 2016 Feb 24.

Key Laboratory for Regenerative Medicine, Ministry of Education, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China School of Biomedical Sciences Core Laboratory, The Chinese University of Hong Kong Shenzhen Research Institute, Shenzhen, China

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http://dx.doi.org/10.1095/biolreprod.115.135921DOI Listing
April 2016

Inflammation and functional iron deficiency regulate fibroblast growth factor 23 production.

Kidney Int 2016 Jan 4;89(1):135-46. Epub 2016 Jan 4.

Division of Nephrology and Hypertension, Department of Medicine and Center for Translational Metabolism and Health, Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00852538150002
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http://dx.doi.org/10.1038/ki.2015.290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854810PMC
January 2016

Inflammation regulates TMPRSS6 expression via STAT5.

PLoS One 2013 23;8(12):e82127. Epub 2013 Dec 23.

Program in Anemia Signaling Research, Division of Nephrology, Program in Membrane Biology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082127PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3871639PMC
March 2015

Exogenous BMP7 corrects plasma iron overload and bone loss in Bmp6-/- mice.

Int Orthop 2015 Jan 11;39(1):161-72. Epub 2014 Oct 11.

Center for Translational and Clinical Research, University of Zagreb School of Medicine, Salata 11, 10000, Zagreb, Croatia,

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http://dx.doi.org/10.1007/s00264-014-2550-4DOI Listing
January 2015

Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-α, and IL-1β.

Am J Physiol Endocrinol Metab 2014 Jul 3;307(2):E186-98. Epub 2014 Jun 3.

Key Laboratory for Regenerative Medicine, Ministry of Education, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China; School of Biomedical Sciences Core Laboratory, The Chinese University of Hong Kong Shenzhen Research Institute, Shenzhen, China;

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http://dx.doi.org/10.1152/ajpendo.00652.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4101637PMC
July 2014

The role of TMPRSS6/matriptase-2 in iron regulation and anemia.

Front Pharmacol 2014 19;5:114. Epub 2014 May 19.

Program in Anemia Signaling Research, Division of Nephrology, Program in Membrane Biology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School Boston, MA, USA.

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http://dx.doi.org/10.3389/fphar.2014.00114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053654PMC
June 2014

Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity.

Circulation 2014 Apr 31;129(16):1677-87. Epub 2014 Jan 31.

Center for Systems Biology, Massachusetts General Hospital, Boston (I.H., I.T., L.M.S.G., C.S.R., G.F.W., Y.I., C.W., H.Y.L., M.N., R.W., F.K.S.); Department of Internal Medicine VI, Infectious Diseases, Immunology Rheumatology, Pneumology, University Hospital of Innsbruck, Innsbruck, Austria (I.T.); Toronto General Research Institute, University Health Network, Toronto, ON, Canada (C.S.R., N.D.); Department of Medicine, University of California, San Diego, La Jolla (A.G., J.L.W.); Department of Gastroenterology, Hepatology and Infectious Diseases, University of Duesseldorf, Duesseldorf, Germany (T.A.W.H.); Department of Cardiology and Angiology I, University Heart Center Freiburg, Freiburg, Germany (C.W., A.Z.); Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA (G.K.S., P.L.); Department of Pathology (J.B.) and Division of Vascular Surgery (B.B.R.), Peter Munk Cardiac Centre, Toronto General Hospital, Toronto, ON, Canada; and Department of Systems Biology, Harvard Medical School, Boston, MA (R.W.).

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.113.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.006381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997655PMC
April 2014

BuMPing iron with modified heparins.

Blood 2014 Mar;123(10):1440-1

MASSACHUSETTS GENERAL HOSPITAL.

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http://dx.doi.org/10.1182/blood-2014-01-549519DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945857PMC
March 2014

The liver: conductor of systemic iron balance.

Blood 2014 Jan 7;123(2):168-76. Epub 2013 Nov 7.

Program in Anemia Signaling Research, Division of Nephrology, Program in Membrane Biology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1182/blood-2013-06-427757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888285PMC
January 2014

Dragon (repulsive guidance molecule RGMb) inhibits E-cadherin expression and induces apoptosis in renal tubular epithelial cells.

J Biol Chem 2013 Nov 19;288(44):31528-39. Epub 2013 Sep 19.

From the Key Laboratory for Regenerative Medicine, Ministry of Education, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1074/jbc.M113.517573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814749PMC
November 2013

Differential regulation of myeloid leukemias by the bone marrow microenvironment.

Nat Med 2013 Nov 27;19(11):1513-7. Epub 2013 Oct 27.

1] Center for Regenerative Medicine and Cancer Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, USA. [3] Harvard Stem Cell Institute, Cambridge, Massachusetts, USA. [4] Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nm.3364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827980PMC
November 2013

Local proliferation dominates lesional macrophage accumulation in atherosclerosis.

Nat Med 2013 Sep 11;19(9):1166-72. Epub 2013 Aug 11.

1] Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Toronto General Research Institute, University Health Network, Toronto, Ontario, Canada. [3] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. [4] Department of Immunology, University of Toronto, Toronto, Ontario, Canada. [5].

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http://dx.doi.org/10.1038/nm.3258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769444PMC
September 2013

A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats.

Nephrol Dial Transplant 2013 Jul 22;28(7):1733-43. Epub 2013 Jan 22.

Program in Anemia Signaling Research, Division of Nephrology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1093/ndt/gfs584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3707526PMC
July 2013

Hepcidin regulation by BMP signaling in macrophages is lipopolysaccharide dependent.

PLoS One 2012 13;7(9):e44622. Epub 2012 Sep 13.

School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0044622PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441567PMC
March 2013

Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin.

Am J Physiol Renal Physiol 2013 Mar 12;304(5):F553-64. Epub 2012 Dec 12.

1Nephrology Division, MGH Center for Systems Biology, Program in Membrane Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1152/ajprenal.00438.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602717PMC
March 2013

A novel validated enzyme-linked immunosorbent assay to quantify soluble hemojuvelin in mouse serum.

Haematologica 2013 Feb 8;98(2):296-304. Epub 2012 Aug 8.

Program in Anemia Signaling Research, Division of Nephrology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.3324/haematol.2012.070136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561439PMC
February 2013

Repulsive guidance molecule (RGM) family proteins exhibit differential binding kinetics for bone morphogenetic proteins (BMPs).

PLoS One 2012 27;7(9):e46307. Epub 2012 Sep 27.

Program in Anemia Signaling Research, Nephrology Division, Program in Membrane Biology, and Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0046307PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459908PMC
February 2013

Mechanisms of anemia in CKD.

J Am Soc Nephrol 2012 Oct 30;23(10):1631-4. Epub 2012 Aug 30.

Massachusetts General Hospital, 185 Cambridge Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.1681/ASN.2011111078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458456PMC
October 2012

Divergent roles of Smad3 and PI3-kinase in murine adriamycin nephropathy indicate distinct mechanisms of proteinuria and fibrogenesis.

Kidney Int 2012 Sep 25;82(5):525-36. Epub 2012 Apr 25.

Division of Kidney Diseases and Children's Memorial Research Center, Children's Memorial Hospital, Chicago, IL, USA.

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http://dx.doi.org/10.1038/ki.2012.139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3425729PMC
September 2012

Transforming growth factor-β and the kidney revisited: introduction.

Authors:
Herbert Y Lin

Semin Nephrol 2012 May;32(3):225-7

Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.semnephrol.2012.04.010DOI Listing
May 2012

Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation.

Am J Hematol 2012 Apr 31;87(4):392-400. Epub 2012 Jan 31.

Program in Membrane Biology, Division of Nephrology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1002/ajh.23110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653431PMC
April 2012

The bone morphogenetic protein-hepcidin axis as a therapeutic target in inflammatory bowel disease.

Inflamm Bowel Dis 2012 Jan 23;18(1):112-9. Epub 2011 Feb 23.

Mucosal Immunology Laboratory, Massachusetts General Hospital, Charlestown, USA.

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http://dx.doi.org/10.1002/ibd.21675DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3139830PMC
January 2012

Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe.

Gastroenterology 2011 Nov 13;141(5):1907-14. Epub 2011 Jul 13.

Program in Membrane Biology, Division of Nephrology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1053/j.gastro.2011.06.077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3634343PMC
November 2011

The molecular pathogenesis of hereditary hemochromatosis.

Semin Liver Dis 2011 Aug 7;31(3):280-92. Epub 2011 Sep 7.

Program in Membrane Biology, Division of Nephrology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1055/s-0031-1286059DOI Listing
August 2011

Regulation of TMPRSS6 by BMP6 and iron in human cells and mice.

Blood 2011 Jul 26;118(3):747-56. Epub 2011 May 26.

Program in Membrane Biology, Division of Nephrology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1182/blood-2011-04-348698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142910PMC
July 2011

Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophages.

J Immunol 2011 Feb 27;186(3):1369-76. Epub 2010 Dec 27.

Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.4049/jimmunol.1002047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3670585PMC
February 2011

BMP signaling modulates hepcidin expression in zebrafish embryos independent of hemojuvelin.

PLoS One 2011 Jan 21;6(1):e14553. Epub 2011 Jan 21.

Division of Hematology/Oncology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0014553PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3024971PMC
January 2011

Altered hepatic BMP signaling pathway in human HFE hemochromatosis.

Blood Cells Mol Dis 2010 Dec 21;45(4):308-12. Epub 2010 Sep 21.

Center for Hemochromatosis, University Hospital of Modena, Modena, Italy.

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http://dx.doi.org/10.1016/j.bcmd.2010.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295241PMC
December 2010

BMP6 treatment compensates for the molecular defect and ameliorates hemochromatosis in Hfe knockout mice.

Gastroenterology 2010 Nov 1;139(5):1721-9. Epub 2010 Aug 1.

Program in Membrane Biology, Nephrology Division, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1053/j.gastro.2010.07.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295242PMC
November 2010

Dragon enhances BMP signaling and increases transepithelial resistance in kidney epithelial cells.

J Am Soc Nephrol 2010 Apr 18;21(4):666-77. Epub 2010 Feb 18.

Center for Systems Biology, Program in Membrane Biology and Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1681/ASN.2009050511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844302PMC
April 2010

Molecular mechanisms of hepcidin regulation: implications for the anemia of CKD.

Am J Kidney Dis 2010 Apr 26;55(4):726-41. Epub 2010 Feb 26.

Program in Membrane Biology, Division of Nephrology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1053/j.ajkd.2009.12.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2905036PMC
April 2010

The RGM/DRAGON family of BMP co-receptors.

Cytokine Growth Factor Rev 2009 Oct-Dec;20(5-6):389-98. Epub 2009 Nov 7.

Program in Membrane Biology, Division of Nephrology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02472, USA.

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http://dx.doi.org/10.1016/j.cytogfr.2009.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715994PMC
March 2010

Selective modulation of TLR4-activated inflammatory responses by altered iron homeostasis in mice.

J Clin Invest 2009 Nov 5;119(11):3322-8. Epub 2009 Oct 5.

Mucosal Immunology Laboratory, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1172/JCI39939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769199PMC
November 2009

Bone morphogenetic protein signaling is impaired in an HFE knockout mouse model of hemochromatosis.

Gastroenterology 2009 Oct 7;137(4):1489-97. Epub 2009 Jul 7.

Division of Nephrology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1053/j.gastro.2009.06.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757523PMC
October 2009

BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.

Nat Genet 2009 Apr 1;41(4):482-7. Epub 2009 Mar 1.

Program in Membrane Biology, Division of Nephrology, Center for Systems Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/ng.335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2810136PMC
April 2009

The soluble transforming growth factor-beta receptor: advantages and applications.

Int J Biochem Cell Biol 2009 Mar 1;41(3):472-6. Epub 2008 Feb 1.

Program in Membrane Biology, Center for Systems Biology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.biocel.2008.01.026DOI Listing
March 2009

Effects of the renal medullary pH and ionic environment on vasopressin binding and signaling.

Kidney Int 2008 Dec 27;74(12):1557-67. Epub 2008 Aug 27.

Program in Membrane Biology and Nephrology Division, MGH Center for Systems Biology, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1038/ki.2008.412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730289PMC
December 2008

Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin.

Blood 2008 May 7;111(10):5195-204. Epub 2008 Mar 7.

Program in Membrane Biology and Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1182/blood-2007-09-111567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2384142PMC
May 2008

Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism.

Nat Chem Biol 2008 Jan 18;4(1):33-41. Epub 2007 Nov 18.

Cardiovascular Research Center and Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, 149 13th Street, Charlestown, Massachusetts 02129, USA.

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http://www.nature.com/articles/nchembio.2007.54
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http://dx.doi.org/10.1038/nchembio.2007.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727650PMC
January 2008

Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance.

J Clin Invest 2007 Jul;117(7):1933-9

Program in Membrane Biology and Nephrology Division, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1172/JCI31342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904317PMC
July 2007

Repulsive guidance molecule RGMa alters utilization of bone morphogenetic protein (BMP) type II receptors by BMP2 and BMP4.

J Biol Chem 2007 Jun 1;282(25):18129-40. Epub 2007 May 1.

Program in Membrane Biology and the Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.

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http://dx.doi.org/10.1074/jbc.M701679200DOI Listing
June 2007

Alix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R.

Am J Physiol Renal Physiol 2007 May 6;292(5):F1303-13. Epub 2007 Feb 6.

Cellular Biophysics Laboratory, Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas, USA.

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http://dx.doi.org/10.1152/ajprenal.00441.2005DOI Listing
May 2007

Evidence for a role of transforming growth factor (TGF)-beta1 in the induction of postglomerular albuminuria in diabetic nephropathy: amelioration by soluble TGF-beta type II receptor.

Diabetes 2007 Feb;56(2):380-8

Program in Membrane Biology, Division of Nephrology, Department of Medicine, Massachusetts General Hospital/Harvard Medical School, Simches Research Center, 185 Cambridge Street, Boston, MA 02114, USA.

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http://dx.doi.org/10.2337/db06-1018DOI Listing
February 2007

Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression.

Nat Genet 2006 May 9;38(5):531-9. Epub 2006 Apr 9.

Program in Membrane Biology and Nephrology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ng1777DOI Listing
May 2006

Repulsive guidance molecule (RGMa), a DRAGON homologue, is a bone morphogenetic protein co-receptor.

J Biol Chem 2005 Aug 23;280(33):29820-7. Epub 2005 Jun 23.

Program in Membrane Biology and Division of Nephrology, Department of Medicine, Harvard Medical School, Boston, MA 02129, USA.

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http://dx.doi.org/10.1074/jbc.M503511200DOI Listing
August 2005

Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway.

Am J Physiol Cell Physiol 2005 Jun 26;288(6):C1390-401. Epub 2005 Jan 26.

Program in Membrane Biology and Renal Unit, Department of Medicine, Massachusetts General Hospital East, 149 13th St., Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1152/ajpcell.00353.2004DOI Listing
June 2005

DRAGON, a bone morphogenetic protein co-receptor.

J Biol Chem 2005 Apr 25;280(14):14122-9. Epub 2005 Jan 25.

Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02129, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M410034200
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http://dx.doi.org/10.1074/jbc.M410034200DOI Listing
April 2005

Reconstitution and analysis of soluble inhibin and activin receptor complexes in a cell-free system.

J Biol Chem 2004 Dec 8;279(51):53126-35. Epub 2004 Oct 8.

Program in Membrane Biology and the Renal Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.

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http://dx.doi.org/10.1074/jbc.M408090200DOI Listing
December 2004

Differential actions of follistatin and follistatin-like 3.

Mol Cell Endocrinol 2004 Oct;225(1-2):25-8

Reproductive Endocrine Unit, BHX-5, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/j.mce.2004.02.009DOI Listing
October 2004

In the absence of type III receptor, the transforming growth factor (TGF)-beta type II-B receptor requires the type I receptor to bind TGF-beta2.

J Biol Chem 2004 May 2;279(21):22765-72. Epub 2004 Mar 2.

Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charleston, Massachusetts 02129, USA.

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http://dx.doi.org/10.1074/jbc.M401350200DOI Listing
May 2004

Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-beta-induced nuclear accumulation.

Am J Physiol Cell Physiol 2003 Oct 11;285(4):C823-30. Epub 2003 Jun 11.

Program in Membrane Biology and Renal Unit, Massachusetts General Hospital, and Department of Medicine, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1152/ajpcell.00053.2003DOI Listing
October 2003

Functional role of the NPxxY motif in internalization of the type 2 vasopressin receptor in LLC-PK1 cells.

Am J Physiol Cell Physiol 2003 Oct 11;285(4):C750-62. Epub 2003 Jun 11.

Program in Membrane Biology and Renal Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1152/ajpcell.00477.2002DOI Listing
October 2003