Herbert B Newton

Herbert B Newton

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Herbert B Newton

Herbert B Newton

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Successful Intrathecal Rituximab Administration in Refractory Nonteratoma Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A Case Report.

J Neurosci Nurs 2019 Aug;51(4):194-197

Questions or comments about this article may be directed to Maritsa Casares, BSN CNRN, at She is an Adult Clinical Coordinator, Florida Epilepsy Center, Florida Hospital, Orlando, FL. Holly J. Skinner, DO, is Epileptologist and Sleep Specialist, Florida Epilepsy Center: Florida Hospital Medical Group, Florida Hospital, Orlando, FL. Elakkat D. Gireesh, MD, is Epileptologist, Florida Epilepsy Center: Florida Hospital Medical Group, Florida Hospital, Orlando, FL. Christina Wombles, ARNP, is Nurse Practitioner, Florida Epilepsy Center: Florida Hospital Medical Group, Florida Hospital, Orlando, FL. Josephine Schweitzer, MSW, is Social Worker, Florida Epilepsy Center, Florida Hospital, Orlando, FL. P. Gage Gwyn, PhD ARNP, is Nurse Practitioner, Florida Hospital Medical Group, NeuroOncology Center, Orlando, FL. Herbert B. Newton, MD, is NeuroOncologist, Florida Hospital Medical Group, NeuroOncology Center, Orlando, FL. Sherif M. Makar, MD, is NeuroOncologist, Florida Hospital Medical Group, NeuroOncology Center, Orlando, FL. Kihyeong Lee, MD MSN, is Medical Director, Florida Epilepsy Center: Florida Hospital Medical Group, Florida Hospital, Orlando, FL. Michael Westerveld, PhD ABPP, is Director, Florida Hospital Medical Group, Florida Center for Neuropsychology, Orlando, FL.

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http://dx.doi.org/10.1097/JNN.0000000000000450DOI Listing
August 2019

Phase II multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma.

Neuro Oncol 2016 08 2;18(8):1137-45. Epub 2016 Feb 2.

Brigham and Women's Hospital/Harvard Medical School, Massachusetts (L.A.W., E.A.C.); Advantagene, Inc., Auburndale, Massachusetts (A.G.M., L.K.A., E.A.-C.); Ohio State University, Columbus, Ohio (S.D.B., R.C., J.M.M., J.C.G., H.B.N.); University Hospitals Seidman Cancer Center/ Case Western Reserve University, Cleveland, Ohio (S.S.L.); City of Hope, Duarte, California (B.B., J.B.); Houston Methodist Hospital, Houston, Texas (B.S.T., T.W.T., D.S.B., P.Z.N.).

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http://dx.doi.org/10.1093/neuonc/now002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933478PMC
August 2016

Central Nervous System Cancers, Version 1.2015.

J Natl Compr Canc Netw 2015 Oct;13(10):1191-202

From University of Alabama at Birmingham Comprehensive Cancer Center; City of Hope Comprehensive Cancer Center; The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; Yale Cancer Center/Smilow Cancer Hospital; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; The University of Texas MD Anderson Cancer Center; UCSF Helen Diller Family Comprehensive Cancer Center; University of Washington/Seattle Cancer Care Alliance; Roswell Park Cancer Institute; Duke Cancer Institute; UC San Diego Moores Cancer Center; University of Michigan Comprehensive Cancer Center; Memorial Sloan Kettering Cancer Center; St. Jude Children's Research Hospital/University of Tennessee Health Science Center; Massachusetts General Hospital Cancer Center; American Brain Tumor Association; Vanderbilt-Ingram Cancer Center; Mayo Clinic Cancer Center; Robert H. Lurie Comprehensive Cancer Center of Northwestern University; Stanford Cancer Institute; Fred & Pamela Buffet Cancer Center; Huntsman Cancer Institute at the University of Utah; Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; Moffitt Cancer Center; Fox Chase Cancer Center; Dana-Farber/Brigham and Women's Cancer Center; National Comprehensive Cancer Network.

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http://www.jnccn.org/content/13/10/1191.full.pdf
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http://dx.doi.org/10.6004/jnccn.2015.0148DOI Listing
October 2015

Survival outcomes and safety of carmustine wafers in the treatment of high-grade gliomas: a meta-analysis.

J Neurooncol 2015 Apr 29;122(2):367-82. Epub 2015 Jan 29.

Department of Neuro-Oncology, Florida Hospital Cancer Institute, 2501 N. Orange Avenue, Suite 286, Orlando, FL, 32804, USA.

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http://dx.doi.org/10.1007/s11060-015-1724-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368843PMC
April 2015

Central nervous system cancers, version 2.2014. Featured updates to the NCCN Guidelines.

J Natl Compr Canc Netw 2014 Nov;12(11):1517-23

From University of Alabama at Birmingham Comprehensive Cancer Center; City of Hope Comprehensive Cancer Center; The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; The University of Texas MD Anderson Cancer Center; UCSF Helen Diller Family Comprehensive Cancer Center; University of Washington/Seattle Cancer Care Alliance; Memorial Sloan Kettering Cancer Center; Roswell Park Cancer Institute; Duke Cancer Institute; UC San Diego Moores Cancer Center; American Brain Tumor Association; University of Michigan Comprehensive Cancer Center; St. Jude Children's Research Hospital/The University of Tennessee Health Science Center; Massachusetts General Hospital Cancer Center; Vanderbilt-Ingram Cancer Center; Robert H. Lurie Comprehensive Cancer Center of Northwestern University; Stanford Comprehensive Cancer Center; Fred & Pamela Buffett Cancer Center at The Nebraska Medical Center; Huntsman Cancer Institute at the University of Utah; Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine; Moffitt Cancer Center; Dana-Farber/Brigham and Women's Cancer Center; and National Comprehensive Cancer Network.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4337873PMC
http://dx.doi.org/10.6004/jnccn.2014.0151DOI Listing
November 2014

Neurosarcoidosis: clinical review of a disorder with challenging inpatient presentations and diagnostic considerations.

Neurohospitalist 2014 Apr;4(2):94-101

Department of Neurology, Wexner Medical Center and James Cancer Hospital, The Ohio State University, Columbus, OH, USA ; Department of Neurosurgery, Wexner Medical Center and James Cancer Hospital, The Ohio State University, Columbus, OH, USA ; Department of Oncology, Wexner Medical Center and James Cancer Hospital, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1177/1941874413519447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3975794PMC
April 2014

Bevacizumab for glioblastoma refractory to vascular endothelial growth factor receptor inhibitors.

J Neurooncol 2012 Apr 28;107(2):407-11. Epub 2011 Dec 28.

Department of Neurology and the Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.

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http://dx.doi.org/10.1007/s11060-011-0768-1DOI Listing
April 2012

Ependymomas, neuronal and mixed neuronal-glial tumors, dysembroblastic neuroepithelial tumors, pleomorphic xanthoastrocytomas, and pilocytic astrocytomas.

Handb Clin Neurol 2012 ;105:551-67

Department of Neurology, The Ohio State University Medical Center, Columbus, OH, USA.

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http://dx.doi.org/10.1016/B978-0-444-53502-3.00008-2DOI Listing
April 2012

Neurological complications of chemotherapy to the central nervous system.

Authors:
Herbert B Newton

Handb Clin Neurol 2012 ;105:903-16

Department of Nedurology, Ohio State University Medical Center, Columbus, OH, USA.

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https://linkinghub.elsevier.com/retrieve/pii/B97804445350230
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http://dx.doi.org/10.1016/B978-0-444-53502-3.00031-8DOI Listing
April 2012

Successful Gamma Knife-based stereotactic radiosurgery treatment for medically intractable heterotopia-based seizure disorder.

Clin Neurol Neurosurg 2011 Dec 30;113(10):934-6. Epub 2011 Jul 30.

Department of Neurological Surgery, The Ohio State University Medical Center, Columbus, OH, USA.

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http://dx.doi.org/10.1016/j.clineuro.2011.06.012DOI Listing
December 2011

Emergent pulmonary embolectomy and advanced glioblastoma multiforme.

Case Rep Med 2010 20;2010:862028. Epub 2010 Dec 20.

Division of Cardiothoracic Surgery, The Ohio State University Medical Center, N817 Doan Hall, 410 W 10th Avenue, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1155/2010/862028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014852PMC
July 2011

Clinical presentation, histology, and treatment in 430 patients with primary tumors of the spinal cord, spinal meninges, or cauda equina.

J Neurosurg Spine 2010 Jul;13(1):67-77

Departments of Neurosurgery, University of Illinois at Chicago Medical Center, Chicago, Illinois, USA.

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http://dx.doi.org/10.3171/2010.3.SPINE09430DOI Listing
July 2010

Primary meningeal CNS lymphoma treated with intra-arterial chemotherapy and blood-brain barrier disruption.

J Neurooncol 2008 Dec 30;90(3):329-33. Epub 2008 Aug 30.

College of Medicine, The Ohio State University Medical Center, 370 West 9th Ave, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1007/s11060-008-9667-5DOI Listing
December 2008

A phase II study of thalidomide and irinotecan for treatment of glioblastoma multiforme.

J Neurooncol 2008 Nov 26;90(2):229-35. Epub 2008 Jul 26.

Department of Medicine, Section of Hematology/Oncology, Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center Drive, One Medical Center Drive, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.1007/s11060-008-9655-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885231PMC
November 2008

Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal.

Cancer Res 2008 Nov;68(22):9125-30

Dardinger Laboratory for Neuro-oncology and Neurosciences, Department of Neurological Surgery, The Ohio State University Medical Center and James Comprehensive Cancer Center, Columbus, Ohio 43210

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2629DOI Listing
November 2008

Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3.

Neuro Oncol 2008 Oct 20;10(5):690-9. Epub 2008 Aug 20.

Dardinger Laboratory for Neuro-oncology and Neurosciences, Department of Neurological Surgery, The Ohio State University Medical Center, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1215/15228517-2008-041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2666245PMC
October 2008

CNS germinomas: what is the best treatment strategy?

Expert Rev Neurother 2008 Oct;8(10):1527-36

Department of Radiation Oncology, The University of Texas Medical Branch, Trauma Center, 301 University Boulevard, Galveston, TX 77555-1178, USA.

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http://dx.doi.org/10.1586/14737175.8.10.1527DOI Listing
October 2008

Glioblastoma multiforme.

Authors:
Herbert B Newton

Curr Treat Options Neurol 2008 Jul;10(4):285-94

Herbert B. Newton, MD Dardinger Neuro-Oncology Center, Department of Neurology, Ohio State University Medical Center, 465 Means Hall, 1654 Upham Drive, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1007/s11940-008-0031-zDOI Listing
July 2008

Do pilocytic astrocytomas have a benign course in adult patients?

Authors:
Herbert B Newton

Nat Clin Pract Neurol 2008 Jun 15;4(6):296-7. Epub 2008 Apr 15.

Department of Neurology, Ohio State University Medical Center, Columbus, OH 43210, USA.

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http://www.nature.com/articles/ncpneuro0787
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http://dx.doi.org/10.1038/ncpneuro0787DOI Listing
June 2008

Symptom management and supportive care of the patient with brain metastases.

Authors:
Herbert B Newton

Cancer Treat Res 2007 ;136:53-73

Dardinger Neuro-Oncology Center, Department of Neurology, Ohio State University Hospitals, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1007/978-0-387-69222-7_4DOI Listing
January 2008

Prognosis of refractory neurosarcoidosis altered by thalidomide: a case report.

J Med Case Rep 2008 Jan 28;2:27. Epub 2008 Jan 28.

Dardinger Neuro-Oncology Center, Division of Neuro-Oncology, and Department of Neurology, The Ohio State University Medical Center and James Cancer Hospital & Solove Research Institute, Columbus, Ohio, USA.

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http://dx.doi.org/10.1186/1752-1947-2-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2249602PMC
January 2008

Hydroxyurea chemotherapy in the treatment of meningiomas.

Authors:
Herbert B Newton

Neurosurg Focus 2007 ;23(4):E11

Dardinger Neuro-Oncology Center and Division of Neuro-Oncology, Department of Neurology, The Ohio State University Medical Center, Columbus, Ohio 43210, USA.

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https://thejns.org/view/journals/neurosurg-focus/23/4/articl
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http://dx.doi.org/10.3171/FOC-07/10/E11DOI Listing
December 2007

Small-molecule and antibody approaches to molecular chemotherapy of primary brain tumors.

Authors:
Herbert B Newton

Curr Opin Investig Drugs 2007 Dec;8(12):1009-21

Dardinger Neuro-Oncology Center, Division of Neuro-Oncology, 465 Means Hall, 1654 Upham Drive, Columbus, OH 43210, USA.

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December 2007

Retrospective analysis of the efficacy and tolerability of levetiracetam in patients with metastatic brain tumors.

J Neurooncol 2007 Sep 13;84(3):293-6. Epub 2007 Apr 13.

Dardinger Neuro-Oncology Center and Division of Neuro-Oncology, Department of Neurology, Ohio State University Medical Center, and James Cancer Hospital & Solove Research Institute, Columbus, OH, USA.

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http://link.springer.com/10.1007/s11060-007-9373-8
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http://dx.doi.org/10.1007/s11060-007-9373-8DOI Listing
September 2007

Advances in strategies to improve drug delivery to brain tumors.

Authors:
Herbert B Newton

Expert Rev Neurother 2006 Oct;6(10):1495-509

Dardinger Neuro-oncology Center, Division of Neuro-oncology, 465 Means Hall, 1654 Upham Drive, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1586/14737175.6.10.1495DOI Listing
October 2006

Incidence of infusion plan alterations after angiography in patients undergoing intra-arterial chemotherapy for brain tumors.

J Neurooncol 2006 Jun 14;78(2):157-60. Epub 2006 Apr 14.

Division of Neuro-Oncology and Dardinger Neuro-Oncology Center, Department of Neurology, Ohio State University Medical Center and James Cancer Hospital & Solove Research Institute, 465 Means Hall, 1654 Upham Drive, Columbus, Ohio, USA.

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http://link.springer.com/10.1007/s11060-005-9080-2
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http://dx.doi.org/10.1007/s11060-005-9080-2DOI Listing
June 2006

Retrospective analysis of the efficacy and tolerability of levetiracetam in brain tumor patients.

J Neurooncol 2006 May 16;78(1):99-102. Epub 2006 Mar 16.

Dardinger Neuro-Oncology Center and Division of Neuro-Oncology, Department of Neurology, Ohio State University Medical Center, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1007/s11060-005-9070-4DOI Listing
May 2006

Brain tumor imaging and cancer management: the neuro-oncologists perspective.

Top Magn Reson Imaging 2006 Apr;17(2):127-36

Division of Neuro-Oncology, Department of Neurology, Dardinger Neuro-Oncology Center, The Ohio State University Medical Center, Columbus, OH 43210, USA.

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https://insights.ovid.com/crossref?an=00002142-200604000-000
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http://dx.doi.org/10.1097/RMR.0b013e31802bb571DOI Listing
April 2006

Intra-arterial chemotherapy of primary brain tumors.

Authors:
Herbert B Newton

Curr Treat Options Oncol 2005 Nov;6(6):519-30

Dardinger Neuro-Oncology Center and Division of Neuro-Oncology, Department of Neurology, The Ohio State University Medical Center and James Cancer Hospital and Solove Research Institute, 1654 Upham Drive, Columbus, OH 43210, USA.

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http://www.springerlink.com/index/512pu13m3rp50060.pdf
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http://link.springer.com/content/pdf/10.1007/s11864-005-0030
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http://dx.doi.org/10.1007/s11864-005-0030-1DOI Listing
November 2005

Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors. Part 5: apoptosis and cell cycle.

Authors:
Herbert B Newton

Expert Rev Anticancer Ther 2005 Apr;5(2):355-78

Dardinger Neuro-Oncology Center, Department of Neurology, The Ohio State University Hospitals, 465 Means Hall, 1654 Upham Drive, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1586/14737140.5.2.355DOI Listing
April 2005

Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors. Part 4: p53 signaling pathway.

Authors:
Herbert B Newton

Expert Rev Anticancer Ther 2005 Feb;5(1):177-91

Dardinger Neuro-Oncology Center, Department of Neurology, Ohio State University Hospitals, 465 Means Hall, 1654 Upham Drive, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1586/14737140.5.1.177DOI Listing
February 2005

Molecular neuro-oncology and the development of targeted therapeutic strategies for brain tumors. Part 3: brain tumor invasiveness.

Authors:
Herbert B Newton

Expert Rev Anticancer Ther 2004 Oct;4(5):803-21

Dardinger Neuro-Oncology Center, Department of Neurology, Ohio State University Hospitals, 465 Means Hall, 1654 Upham Drive, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1586/14737140.4.5.803DOI Listing
October 2004

Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 2: PI3K/Akt/PTEN, mTOR, SHH/PTCH and angiogenesis.

Authors:
Herbert B Newton

Expert Rev Anticancer Ther 2004 Feb;4(1):105-28

Dardinger Neuro-Oncology Center, Department of Neurology, Ohio State University Hospitals, 465 Means Hall, 1654 Upham Drive, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1586/14737140.4.1.105DOI Listing
February 2004

Molecular neuro-oncology and development of targeted therapeutic strategies for brain tumors. Part 1: Growth factor and Ras signaling pathways.

Authors:
Herbert B Newton

Expert Rev Anticancer Ther 2003 Oct;3(5):595-614

Dardinger Neuro-Oncology Center, Department of Neurology, Ohio State University Hospitals, Columbus 43210, USA.

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http://dx.doi.org/10.1586/14737140.3.5.595DOI Listing
October 2003

Intra-arterial carboplatin and intravenous etoposide for the treatment of metastatic brain tumors.

J Neurooncol 2003 Jan;61(1):35-44

Division of Neuro-Oncology, Department of Neurology, The Ohio State University Medical Center, James Cancer Hospital and Solove Research Institute, Columbus, OH, USA.

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http://dx.doi.org/10.1023/a:1021218207015DOI Listing
January 2003

Visualization of microvascularity in glioblastoma multiforme with 8-T high-spatial-resolution MR imaging.

AJNR Am J Neuroradiol 2002 Oct;23(9):1553-6

Department of Radiology, the Ohio State University Medical Center, 168 Means Hall, 1654 Upham Drive, Columbus, OH 43221, USA.

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October 2002

Chemotherapy for the treatment of metastatic brain tumors.

Authors:
Herbert B Newton

Expert Rev Anticancer Ther 2002 Oct;2(5):495-506

Division of Neuro-Oncology, Department of Neurology, Ohio State University Medical Center and James Cancer Hospital and Solove Research Institute, 1654 Upham Drive, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1586/14737140.2.5.495DOI Listing
October 2002

Intra-arterial carboplatin and intravenous etoposide for the treatment of recurrent and progressive non-GBM gliomas.

J Neurooncol 2002 Jan;56(1):79-86

Department of Neurology, The Ohio State University Medical Center and James Cancer Hospital and Solove Research Institute, Columbus 43210, USA.

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http://dx.doi.org/10.1023/a:1014498225405DOI Listing
January 2002