Heping Xu

Heping Xu

UNVERIFIED PROFILE

Are you Heping Xu?   Register this Author

Register author
Heping Xu

Heping Xu

Publications by authors named "Heping Xu"

Are you Heping Xu?   Register this Author

100Publications

1458Reads

21Profile Views

Microplasma assisted synthesis of gold nanoparticle/graphene oxide nanocomposites and their potential application in SERS sensing.

Nanotechnology 2019 Nov 17;30(45):455603. Epub 2019 Jun 17.

Advanced Composites Research Group (ACRG), School of Mechanical and Aerospace Engineering, Queen's University, Belfast BT9 5AH, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1088/1361-6528/ab2a23DOI Listing
November 2019

Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses.

Immunity 2019 Oct;51(4):696-708.e9

Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA; Center for Microbiome Informatics and Therapeutics, Massachusetts Institute of Technology, Cambridge, MA 02114, USA; Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10747613193037
Publisher Site
http://dx.doi.org/10.1016/j.immuni.2019.09.004DOI Listing
October 2019

Sustained intraocular vascular endothelial growth factor neutralisation does not affect retinal and choroidal vasculature in Ins2 diabetic mice.

Diab Vasc Dis Res 2019 09 26;16(5):440-449. Epub 2019 Apr 26.

Centre for Experimental Medicine, Queen's University Belfast, Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1479164119843092DOI Listing
September 2019

STAT3 activation in circulating myeloid-derived cells contributes to retinal microvascular dysfunction in diabetes.

J Neuroinflammation 2019 Jul 8;16(1):138. Epub 2019 Jul 8.

Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, Northern Ireland, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12974-019-1533-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615157PMC
July 2019

Clinical features, identification, antimicrobial resistance patterns of Nocardia species in China: 2009-2017.

Diagn Microbiol Infect Dis 2019 Jun 29;94(2):165-172. Epub 2018 Dec 29.

Laboratory of Clinical Microbiology and Infectious Diseases, Department of Pulmonary and Critical Care Medicine, China-Japan Friendship Hospital, Beijing, China. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S07328893183080
Publisher Site
http://dx.doi.org/10.1016/j.diagmicrobio.2018.12.007DOI Listing
June 2019

Attenuating Diabetic Vascular and Neuronal Defects by Targeting P2rx7.

Int J Mol Sci 2019 Apr 29;20(9). Epub 2019 Apr 29.

Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast BT9 7BL, Northern Ireland, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20092101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540042PMC
April 2019

Immune regulation in the aging retina.

Prog Retin Eye Res 2019 03 20;69:159-172. Epub 2018 Oct 20.

Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, UK; Aier Eye Institute, Aier School of Ophthalmology, Central South University, China. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S13509462183004
Publisher Site
http://dx.doi.org/10.1016/j.preteyeres.2018.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373845PMC
March 2019

Glucose transporter 1 critically controls microglial activation through facilitating glycolysis.

Mol Neurodegener 2019 01 11;14(1). Epub 2019 Jan 11.

The Wellcome-Wolfson Institute of Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.

View Article

Download full-text PDF

Source
https://molecularneurodegeneration.biomedcentral.com/article
Publisher Site
http://dx.doi.org/10.1186/s13024-019-0305-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329071PMC
January 2019

Molecular Mechanisms Underlying Age-Related Ocular Diseases.

Oxid Med Cell Longev 2018;2018:8476164. Epub 2018 May 21.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis, MN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2018/8476164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5987342PMC
December 2018

Myofibroblasts in macular fibrosis secondary to neovascular age-related macular degeneration - the potential sources and molecular cues for their recruitment and activation.

EBioMedicine 2018 Dec 22;38:283-291. Epub 2018 Nov 22.

The Welcomme-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, UK; Aier Eye Institute, Aier School of Ophthalmology, Central South University, Changsha, Hunan, China. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S23523964183053
Publisher Site
http://dx.doi.org/10.1016/j.ebiom.2018.11.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306402PMC
December 2018

Antagonising Wnt/β-catenin signalling ameliorates lens-capsulotomy-induced retinal degeneration in a mouse model of diabetes.

Diabetologia 2018 11 17;61(11):2433-2446. Epub 2018 Jul 17.

Centre for Experimental Medicine, Wellcome-Wolfson Institute of Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00125-018-4682-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6182657PMC
November 2018

Polarized retinal pigment epithelium generates electrical signals that diminish with age and regulate retinal pathology.

J Cell Mol Med 2018 11 30;22(11):5552-5564. Epub 2018 Aug 30.

Wellcome-Wolfson Institute for Experimental Medicine, Queen's University, Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jcmm.13829DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6201363PMC
November 2018

Cholesterol homeostasis, macrophage malfunction and age-related macular degeneration.

Ann Transl Med 2018 Nov;6(Suppl 1):S55

The Wellcome-Wolfson Institute for Experimental Medicine, Centre for Experimental Medicine, Queen's University Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/atm.2018.10.31DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291610PMC
November 2018

Modulation of three key innate immune pathways for the most common retinal degenerative diseases.

EMBO Mol Med 2018 10;10(10)

Laboratory for Experimental Immunology of the Eye, Department of Ophthalmology, University of Cologne, Cologne, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/emmm.201708259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180304PMC
October 2018

Affinity Maturation Is Impaired by Natural Killer Cell Suppression of Germinal Centers.

Cell Rep 2018 09;24(13):3367-3373.e4

Center for Autoimmune Genomics and Etiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA; Immunology Graduate Training Program, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22111247183137
Publisher Site
http://dx.doi.org/10.1016/j.celrep.2018.08.075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192537PMC
September 2018

Zinc Protects Oxidative Stress-Induced RPE Death by Reducing Mitochondrial Damage and Preventing Lysosome Rupture.

Oxid Med Cell Longev 2017 14;2017:6926485. Epub 2017 Nov 14.

Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast BT9 7BL, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2017/6926485DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733978PMC
August 2018

Collectin-11 Is an Important Modulator of Retinal Pigment Epithelial Cell Phagocytosis and Cytokine Production.

J Innate Immun 2017 4;9(6):529-545. Epub 2017 Aug 4.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000478042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6738776PMC
July 2018

Sustained high glucose exposure sensitizes macrophage responses to cytokine stimuli but reduces their phagocytic activity.

BMC Immunol 2018 07 11;19(1):24. Epub 2018 Jul 11.

Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12865-018-0261-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042333PMC
July 2018

The expression of C1 inhibitor (C1INH) in macrophages is upregulated by retinal pigment epithelial cells - implication in subretinal immune privilege in the aging eye.

Aging (Albany NY) 2018 Jun;10(6):1380-1389

Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/aging.101474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046230PMC
June 2018

Cytokine Signaling Protein 3 Deficiency in Myeloid Cells Promotes Retinal Degeneration and Angiogenesis through Arginase-1 Up-Regulation in Experimental Autoimmune Uveoretinitis.

Am J Pathol 2018 04 13;188(4):1007-1020. Epub 2018 Feb 13.

Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, Belfast, United Kingdom. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2017.12.021DOI Listing
April 2018

Characterization of a Spontaneously Immortalized Murine Müller Glial Cell Line QMMuC-1.

Invest Ophthalmol Vis Sci 2018 03;59(3):1666-1674

Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Northern Ireland, United Kingdom.

View Article

Download full-text PDF

Source
http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
Publisher Site
http://dx.doi.org/10.1167/iovs.17-23293DOI Listing
March 2018

Mechanistical retinal drug targets and challenges.

Adv Drug Deliv Rev 2018 02 23;126:177-184. Epub 2018 Apr 23.

School of Pharmacy, University of Eastern Finland, Kuopio, Finland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.addr.2018.04.016DOI Listing
February 2018

Diabetic retinopathy and dysregulated innate immunity.

Authors:
Heping Xu Mei Chen

Vision Res 2017 10 2;139:39-46. Epub 2017 Jun 2.

Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queen's University Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.visres.2017.04.013DOI Listing
October 2017

PKCζ-dependent upregulation of p27kip1 contributes to oxidative stress induced retinal pigment epithelial cell multinucleation.

Aging (Albany NY) 2017 10;9(10):2052-2068

Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, BT97 BL, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/aging.101299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5680555PMC
October 2017

Association between gene polymorphisms and COPD susceptibility in a Chinese Han population.

Int J Chron Obstruct Pulmon Dis 2017 17;12:931-936. Epub 2017 Mar 17.

Department of Emergency, People's Hospital of Hainan Province, Haikou, Hainan, People's Republic of China.

View Article

Download full-text PDF

Source
https://www.dovepress.com/association-between-rtel1-gene-pol
Publisher Site
http://dx.doi.org/10.2147/COPD.S131246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364006PMC
August 2017

Comprehensive analysis of mouse retinal mononuclear phagocytes.

Nat Protoc 2017 Jun 4;12(6):1136-1150. Epub 2017 May 4.

Laboratory for Experimental Immunology of the Eye, Department of Ophthalmology, University of Cologne, Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nprot.2017.032DOI Listing
June 2017

Topical Delivery of Anti-VEGF Drugs to the Ocular Posterior Segment Using Cell-Penetrating Peptides.

Invest Ophthalmol Vis Sci 2017 05;58(5):2578-2590

Institute of Inflammation and Ageing, University of Birmingham, Birmingham, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.16-20072DOI Listing
May 2017

Higher phagocytic activity of thioglycollate-elicited peritoneal macrophages is related to metabolic status of the cells.

J Inflamm (Lond) 2017 10;14. Epub 2017 Feb 10.

Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Science, Queens University Belfast, Belfast, Northern Ireland UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12950-017-0151-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5301433PMC
February 2017

Genetic polymorphisms and phenotypic analysis of drug-metabolizing enzyme CYP2C19 in a Li Chinese population.

Int J Clin Exp Pathol 2015 1;8(10):13201-8. Epub 2015 Oct 1.

School of Life Sciences, Northwest University Xi'an 710069, Shaanxi, China ; Key Laboratory of High Altitude Environment and Genes Related to Diseases of Tibet Autonomous Region, School of Medicine, Tibet University for Nationalities Xianyang 712082, Shaanxi, China.

View Article

Download full-text PDF

Source
http://www.ijcep.com/files/ijcep0014263.pdf
Web Search
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680464PMC
October 2016

Targeting the complement system for the management of retinal inflammatory and degenerative diseases.

Authors:
Heping Xu Mei Chen

Eur J Pharmacol 2016 Sep 3;787:94-104. Epub 2016 Mar 3.

Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ejphar.2016.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026403PMC
September 2016

Treatment planning study of Volumetric Modulated Arc Therapy and three dimensional field-in-field techniques for left chest-wall cancers with regional lymph nodes.

Rep Pract Oncol Radiother 2016 Nov-Dec;21(6):517-524. Epub 2016 Aug 24.

Cape Breton Cancer Centre, Nova Scotia Health Authority, 1482 George St., Sydney, NS, Canada B1P 1P3.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15071367163005
Publisher Site
http://dx.doi.org/10.1016/j.rpor.2016.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5036511PMC
August 2016

Retinal pigment epithelial cell multinucleation in the aging eye - a mechanism to repair damage and maintain homoeostasis.

Aging Cell 2016 06 15;15(3):436-45. Epub 2016 Feb 15.

Centre for Experimental Medicine, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7 BL, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/acel.12447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4854907PMC
June 2016

Genetic polymorphisms of pharmacogenomic VIP variants in Li nationality of southern China.

Environ Toxicol Pharmacol 2016 Mar 20;42:237-42. Epub 2016 Feb 20.

School of Medicine, Xizang Minzu University, Xianyang, Shaanxi 712082, China; National Engineering Research Center for Miniaturized Detection Systems, Xi'an 710069, China; School of Life Sciences, Northwest University, Xi'an, Shaanxi 710069, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.etap.2016.02.003DOI Listing
March 2016

Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8.

Nat Immunol 2015 Dec 5;16(12):1274-81. Epub 2015 Oct 5.

Division of Immunobiology and the Center for Systems Immunology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni.3287DOI Listing
December 2015

Sustained intraocular VEGF neutralization results in retinal neurodegeneration in the Ins2(Akita) diabetic mouse.

Sci Rep 2015 Dec 16;5:18316. Epub 2015 Dec 16.

Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep18316DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680939PMC
December 2015

Parainflammation, chronic inflammation, and age-related macular degeneration.

Authors:
Mei Chen Heping Xu

J Leukoc Biol 2015 Nov 20;98(5):713-25. Epub 2015 Aug 20.

Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, United Kingdom

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.3RI0615-239RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733662PMC
November 2015

Targeting translocator protein (18 kDa) (TSPO) dampens pro-inflammatory microglia reactivity in the retina and protects from degeneration.

J Neuroinflammation 2015 Nov 2;12:201. Epub 2015 Nov 2.

Department of Ophthalmology, Laboratory for Experimental Immunology of the Eye, University of Cologne, 50931, Cologne, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12974-015-0422-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630900PMC
November 2015

Alterations in Circulating Immune Cells in Neovascular Age-Related Macular Degeneration.

Sci Rep 2015 Nov 17;5:16754. Epub 2015 Nov 17.

Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep16754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648089PMC
November 2015

High-Level Macrolide-Resistant Moraxella catarrhalis and Development of an Allele-Specific PCR Assay for Detection of 23S rRNA Gene A2330T Mutation: A Three-Year Study at a Chinese Tertiary Hospital.

Microb Drug Resist 2015 Oct 29;21(5):507-11. Epub 2015 Apr 29.

1 Department of Clinical Laboratory, Peking Union Medical College Hospital, Peking Union Medical College , Chinese Academy of Medical Sciences, Beijing, China .

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/mdr.2014.0217DOI Listing
October 2015

Wnt signaling in age-related macular degeneration: human macular tissue and mouse model.

J Transl Med 2015 Oct 17;13:330. Epub 2015 Oct 17.

Laboratory of Immunology, National Eye Institute, National Institutes of Health, 10 Center Drive, Bldg. 10, Rm. 10N103, NIH/NEI, Bethesda, MD, 20892-1857, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12967-015-0683-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4609061PMC
October 2015

Culture and characterization of microglia from the adult murine retina.

ScientificWorldJournal 2014 29;2014:894368. Epub 2014 May 29.

Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Institute of Clinical Science-A, Grosvenor Road, Belfast BT12 6BA, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2014/894368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4060747PMC
April 2015

Loss of synaptic connectivity, particularly in second order neurons is a key feature of diabetic retinal neuropathy in the Ins2Akita mouse.

PLoS One 2014 21;9(5):e97970. Epub 2014 May 21.

Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University, Belfast, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0097970PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029784PMC
January 2015

T-B-cell entanglement and ICOSL-driven feed-forward regulation of germinal centre reaction.

Nature 2015 Jan 15;517(7533):214-8. Epub 2014 Oct 15.

Tsinghua-Peking Center for Life Sciences, Laboratory of Dynamic Immunobiology, School of Medicine, Tsinghua University, 100084 Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature13803DOI Listing
January 2015

IL-33 attenuates the development of experimental autoimmune uveitis.

Eur J Immunol 2014 Nov 18;44(11):3320-9. Epub 2014 Oct 18.

Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201444671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4449115PMC
November 2014

Experimental autoimmune uveoretinitis (EAU)-related tissue damage and angiogenesis is reduced in CCL2⁻/⁻CX₃CR1gfp/gfp mice.

Invest Ophthalmol Vis Sci 2014 Oct 23;55(11):7572-82. Epub 2014 Oct 23.

Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.14-15495DOI Listing
October 2014

Intravitreal Injection of Normal Saline Induces Retinal Degeneration in the C57BL/6J Mouse.

Transl Vis Sci Technol 2014 Mar 27;3(2). Epub 2014 Mar 27.

Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/tvst.3.2.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969215PMC
March 2014

Follicular T-helper cells: controlled localization and cellular interactions.

Immunol Cell Biol 2014 Jan 22;92(1):28-33. Epub 2013 Oct 22.

Tsinghua-Peking Center for Life Sciences, Laboratory of Dynamic Immunobiology, School of Medicine, School of Life Sciences, Tsinghua University, Beijing, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/icb.2013.59DOI Listing
January 2014

Identification of a new isoform of the murine Sh2d1a gene and its functional implications.

Sci China Life Sci 2014 Jan 26;57(1):81-7. Epub 2013 Dec 26.

Tsinghua-Peking Center for Life Sciences, Laboratory of Dynamic Immunobiology, School of Medicine, School of Life Sciences, Tsinghua University, Beijing, 100084, China.

View Article

Download full-text PDF

Source
http://link.springer.com/content/pdf/10.1007/s11427-013-4584
Web Search
http://link.springer.com/10.1007/s11427-013-4584-z
Publisher Site
http://dx.doi.org/10.1007/s11427-013-4584-zDOI Listing
January 2014

Age- and light-dependent development of localised retinal atrophy in CCL2(-/-)CX3CR1(GFP/GFP) mice.

PLoS One 2013 18;8(4):e61381. Epub 2013 Apr 18.

Centre for Vision and Vascular Science, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, Northern Ireland, UK.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0061381PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3630229PMC
December 2013

Extremely complex populations of small RNAs in the mouse retina and RPE/choroid.

Invest Ophthalmol Vis Sci 2013 Dec 17;54(13):8140-51. Epub 2013 Dec 17.

Centre for Vision and Vascular Science, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.13-12631DOI Listing
December 2013

Complement expression in retinal pigment epithelial cells is modulated by activated macrophages.

Exp Eye Res 2013 Jul 1;112:93-101. Epub 2013 May 1.

Centre for Vision and Vascular Science, School of Medicine, Dentistry & Biomedical Sciences, Queen's University Belfast, BT12 6BA Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exer.2013.04.016DOI Listing
July 2013

The soluble isoform of CTLA-4 as a regulator of T-cell responses.

Eur J Immunol 2013 May 6;43(5):1274-85. Epub 2013 Mar 6.

Section of Immunology and Infection, Division of Applied Medicine, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201242529DOI Listing
May 2013

Follicular T-helper cell recruitment governed by bystander B cells and ICOS-driven motility.

Nature 2013 Apr;496(7446):523-7

Tsinghua-Peking Center for Life Sciences, Laboratory of Dynamic Immunobiology, School of Medicine, Tsinghua University, Beijing 100084, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature12058DOI Listing
April 2013

Paraquat-induced retinal degeneration is exaggerated in CX3CR1-deficient mice and is associated with increased retinal inflammation.

Invest Ophthalmol Vis Sci 2013 Jan 23;54(1):682-90. Epub 2013 Jan 23.

Centre for Vision and Vascular Science, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Northern Ireland, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.12-10888DOI Listing
January 2013

Good news-bad news: the Yin and Yang of immune privilege in the eye.

Front Immunol 2012 27;3:338. Epub 2012 Nov 27.

Laboratory of Immunology, Lion's Eye Institute, University of Western Australia Perth, WA, Australia ; Ocular Immunology Laboratory, Section of Immunology and Infection, Institute of Medical Sciences, University of Aberdeen Aberdeen, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2012.00338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3515883PMC
December 2012

Expression of complement components and regulators by different subtypes of bone marrow-derived macrophages.

Inflammation 2012 Aug;35(4):1448-61

Centre for Vision and Vascular Science, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Grosvenor Road, BT12 6BA, Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10753-012-9458-1DOI Listing
August 2012

CD11b+ bone marrow-derived monocytes are the major leukocyte subset responsible for retinal capillary leukostasis in experimental diabetes in mouse and express high levels of CCR5 in the circulation.

Am J Pathol 2012 Aug 4;181(2):719-27. Epub 2012 Jun 4.

Department of Ophthalmology, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2012.04.009DOI Listing
August 2012

SU-E-J-20: Evaluation of Image Qualities and Registration of Varian KV-CBCT Images Reconstructed from the Reduced Number of Projections.

Authors:
Heping Xu

Med Phys 2012 Jun;39(6Part6):3656

Cape Breton Cancer Centre, Sydney, NS.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1118/1.4734853DOI Listing
June 2012

Para-inflammation-mediated retinal recruitment of bone marrow-derived myeloid cells following whole-body irradiation is CCL2 dependent.

Glia 2012 May 23;60(5):833-42. Epub 2012 Feb 23.

Centre for Vision and Vascular Science, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Northern Ireland, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/glia.22315DOI Listing
May 2012

Dysregulation in retinal para-inflammation and age-related retinal degeneration in CCL2 or CCR2 deficient mice.

PLoS One 2011 5;6(8):e22818. Epub 2011 Aug 5.

Centre for Vision and Vascular Science, Queen's University Belfast, Belfast, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0022818PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3151263PMC
February 2012

Persistent inflammation subverts thrombospondin-1-induced regulation of retinal angiogenesis and is driven by CCR2 ligation.

Am J Pathol 2012 Jan 7;180(1):235-45. Epub 2011 Nov 7.

Centre for Vision and Vascular Science, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2011.09.020DOI Listing
January 2012

Quantitative in situ analysis of claudin expression at the blood-retinal barrier.

Methods Mol Biol 2011 ;762:321-31

Centre for Vision and Vascular Science, Queen's University Belfast, Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-61779-185-7_23DOI Listing
November 2011

Complement gene expression and regulation in mouse retina and retinal pigment epithelium/choroid.

Mol Vis 2011 14;17:1588-97. Epub 2011 Jun 14.

Centre for Vision and Vascular Science, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123163PMC
November 2011

Cataract surgery induces retinal pro-inflammatory gene expression and protein secretion.

Invest Ophthalmol Vis Sci 2011 Jan 5;52(1):249-55. Epub 2011 Jan 5.

Centre for Vision and Vascular Science, Queen's University Belfast, Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.10-6001DOI Listing
January 2011

Immune activation in retinal aging: a gene expression study.

Invest Ophthalmol Vis Sci 2010 Nov 10;51(11):5888-96. Epub 2010 Jun 10.

Centre for Vision and Vascular Science, School of Medicine, Dentistry, and Biomedical Sciences, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.09-5103DOI Listing
November 2010

Inhibition of the alternative pathway of complement activation reduces inflammation in experimental autoimmune uveoretinitis.

Eur J Immunol 2010 Oct;40(10):2870-81

Centre for Vision and Vascular Science, Queen's University Belfast, Belfast, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/eji.201040323DOI Listing
October 2010

Dendritic cell physiology and function in the eye.

Immunol Rev 2010 Mar;234(1):282-304

Section of Immunology and Infection, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.0105-2896.2009.00873.xDOI Listing
March 2010

Development of experimental autoimmune uveitis: efficient recruitment of monocytes is independent of CCR2.

Invest Ophthalmol Vis Sci 2009 Sep 8;50(9):4288-94. Epub 2009 Apr 8.

Division of Applied Medicine, University of Aberdeen, Aberdeen, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.09-3434DOI Listing
September 2009

Para-inflammation in the aging retina.

Prog Retin Eye Res 2009 Sep 26;28(5):348-68. Epub 2009 Jun 26.

Immunology and Infection, Division of Applied Medicine, University of Aberdeen School of Medicine, Foresterhill, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.preteyeres.2009.06.001DOI Listing
September 2009

Up-regulation of complement factor B in retinal pigment epithelial cells is accompanied by complement activation in the aged retina.

Exp Eye Res 2008 Dec 26;87(6):543-50. Epub 2008 Sep 26.

Department of Ophthalmology, University of Aberdeen, Institute of Medical Sciences, Aberdeen, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exer.2008.09.005DOI Listing
December 2008

A clinical grading system for retinal inflammation in the chronic model of experimental autoimmune uveoretinitis using digital fundus images.

Exp Eye Res 2008 Oct 26;87(4):319-26. Epub 2008 Jun 26.

Department of Ophthalmology, University of Aberdeen, Institute of Medical Sciences, Foresterhill, Aberdeen, AB25 2ZD, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exer.2008.06.012DOI Listing
October 2008

Critical but divergent roles for CD62L and CD44 in directing blood monocyte trafficking in vivo during inflammation.

Blood 2008 Aug 7;112(4):1166-74. Epub 2008 Apr 7.

Department of Ophthalmology, University of Aberdeen Institute of Medical Sciences, Aberdeen, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2007-06-098327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2515150PMC
August 2008

Characterization of a spontaneous mouse retinal pigment epithelial cell line B6-RPE07.

Invest Ophthalmol Vis Sci 2008 Aug 17;49(8):3699-706. Epub 2008 Apr 17.

Department of Ophthalmology, School of Medicine, Institute of Medical Sciences, University of Aberdeen, Scotland, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.07-1522DOI Listing
August 2008

Retinal microglia and uveal tract dendritic cells and macrophages are not CX3CR1 dependent in their recruitment and distribution in the young mouse eye.

Invest Ophthalmol Vis Sci 2008 Apr;49(4):1599-608

School of Anatomy and Human Biology, The University of Western Australia, Crawley, Western Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.07-0953DOI Listing
April 2008

Age-dependent accumulation of lipofuscin in perivascular and subretinal microglia in experimental mice.

Aging Cell 2008 Jan 26;7(1):58-68. Epub 2007 Nov 26.

Department of Ophthalmology, Institute of Medical Sciences, School of Medicine, University of Aberdeen, Scotland, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1474-9726.2007.00351.xDOI Listing
January 2008

Anti-inflammatory property of the cannabinoid receptor-2-selective agonist JWH-133 in a rodent model of autoimmune uveoretinitis.

J Leukoc Biol 2007 Sep 30;82(3):532-41. Epub 2007 May 30.

Department of Ophthalmology, School of Medicine, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZD, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1189/jlb.0307159DOI Listing
September 2007

Turnover of resident retinal microglia in the normal adult mouse.

Glia 2007 Aug;55(11):1189-98

Department of Ophthalmology, Institute of Medical Sciences, University of Aberdeen, Aberdeen, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/glia.20535DOI Listing
August 2007

LYVE-1-positive macrophages are present in normal murine eyes.

Invest Ophthalmol Vis Sci 2007 May;48(5):2162-71

Department of Ophthalmology, School of Medicine, Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.06-0783DOI Listing
May 2007

Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments.

Exp Eye Res 2007 Apr 31;84(4):635-45. Epub 2006 Dec 31.

Department of Ophthalmology, School of Medicine, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, Scotland AB25 2ZD, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.exer.2006.11.015DOI Listing
April 2007

Identification of novel dendritic cell populations in normal mouse retina.

Invest Ophthalmol Vis Sci 2007 Apr;48(4):1701-10

Department of Ophthalmology, Institute of Medical Sciences, University of Aberdeen, Foresterhill, Aberdeen, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.06-0697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2446435PMC
April 2007

Investigation of light propagation models to determine the optical properties of tissue from interstitial frequency domain fluence measurements.

J Biomed Opt 2006 Jul-Aug;11(4):041104

Juravinski Cancer Centre, Department of Medical Physics, 699 Concession Street, Hamilton, Ontario L8V 5C2 Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1117/1.2241609DOI Listing
January 2007

Application of the modified spherical harmonics method to some problems in biomedical optics.

Phys Med Biol 2006 Jun 6;51(12):N247-51. Epub 2006 Jun 6.

Department of Medical Physics, Juravinski Cancer Centre, McMaster University, Hamilton, Ontario, L8V 5C2, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1088/0031-9155/51/12/N03DOI Listing
June 2006

Involvement of CCR5 in the passage of Th1-type cells across the blood-retina barrier in experimental autoimmune uveitis.

J Leukoc Biol 2006 Mar 19;79(3):435-43. Epub 2005 Dec 19.

Department of Ophthalmology, University of Aberdeen Medical School, Foresterhill, Aberdeen, AB25 2ZD, UK.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1189/jlb.0305130
Publisher Site
http://dx.doi.org/10.1189/jlb.0305130DOI Listing
March 2006

Leukocyte diapedesis in vivo induces transient loss of tight junction protein at the blood-retina barrier.

Invest Ophthalmol Vis Sci 2005 Jul;46(7):2487-94

Department of Ophthalmology, School of Medicine, University of Aberdeen, Aberdeen, Scotland, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1167/iovs.04-1333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2478725PMC
July 2005