Henry R Kranzler

Henry R Kranzler

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Henry R Kranzler

Publications by authors named "Henry R Kranzler"

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A meta-analysis of the efficacy of gabapentin for treating alcohol use disorder.

Addiction 2019 Sep 5;114(9):1547-1555. Epub 2019 Jun 5.

Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/add.14655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682454PMC
September 2019

Reduction in non-abstinent World Health Organization (WHO) drinking risk levels and drug use disorders: 3-year follow-up results in the US general population.

Drug Alcohol Depend 2019 Aug 29;201:16-22. Epub 2019 May 29.

Columbia University Mailman School of Public Health, 722 West 168th Street, New York, NY, 10032, USA; New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY, 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2019.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662197PMC
August 2019

Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study.

Depress Anxiety 2019 Aug 6. Epub 2019 Aug 6.

U.S. Department of Veterans Affairs National Center for PTSD, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, Connecticut.

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http://dx.doi.org/10.1002/da.22912DOI Listing
August 2019

Pharmacogenetics of alcohol use disorder treatments: an update.

Expert Opin Drug Metab Toxicol 2019 Jul 11;15(7):553-564. Epub 2019 Jun 11.

a Mental Illness Research, Education and Clinical Center , Crescenz VAMC , Philadelphia , PA , USA.

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http://dx.doi.org/10.1080/17425255.2019.1628218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614002PMC
July 2019

Genome-wide scan identifies opioid overdose risk locus close to MCOLN1.

Addict Biol 2019 Jul 30:e12811. Epub 2019 Jul 30.

Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine and VA CT Healthcare Center, New Haven, CT, USA.

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http://dx.doi.org/10.1111/adb.12811DOI Listing
July 2019

Cognitive Behavioral Therapy for Insomnia in Alcohol-Dependent Veterans: A Randomized, Controlled Pilot Study.

Alcohol Clin Exp Res 2019 Jun 29;43(6):1244-1253. Epub 2019 Apr 29.

Corporal Michael J. Crescenz VA Medical Center , Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/acer.14030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551284PMC
June 2019

Opioid Use and Rate of Nicotine Metabolism among Pregnant Smokers.

Nicotine Tob Res 2019 May 7. Epub 2019 May 7.

UConn Health, School of Medicine, Farmington Ave, Farmington, CT.

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http://dx.doi.org/10.1093/ntr/ntz073DOI Listing
May 2019

Reduction in non-abstinent WHO drinking risk levels and depression/anxiety disorders: 3-year follow-up results in the US general population.

Drug Alcohol Depend 2019 04 14;197:228-235. Epub 2019 Feb 14.

Columbia University Mailman School of Public Health, 722 West 168th Street, New York, NY 10032, USA; New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440807PMC
April 2019

Longitudinal Drinking Patterns and Their Clinical Correlates in Million Veteran Program Participants.

Alcohol Clin Exp Res 2019 Mar 3;43(3):465-472. Epub 2019 Feb 3.

VA Connecticut Healthcare System , West Haven, Connecticut.

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http://dx.doi.org/10.1111/acer.13951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691890PMC
March 2019

Alcohol-responsive genes identified in human iPSC-derived neural cultures.

Transl Psychiatry 2019 03 12;9(1):96. Epub 2019 Mar 12.

Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT, 06030-1410, USA.

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http://dx.doi.org/10.1038/s41398-019-0426-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414668PMC
March 2019

Genomewide Study of Epigenetic Biomarkers of Opioid Dependence in European- American Women.

Sci Rep 2019 Mar 15;9(1):4660. Epub 2019 Mar 15.

Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.

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http://www.nature.com/articles/s41598-019-41110-7
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http://dx.doi.org/10.1038/s41598-019-41110-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420601PMC
March 2019

Randomized Trial of Nicotine Inhaler for Pregnant Smokers.

Am J Obstet Gynecol MFM 2019 Mar 27;1(1):10-18. Epub 2019 Mar 27.

Department of Medicine, University of Connecticut School of Medicine, Farmington, CT.

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http://dx.doi.org/10.1016/j.ajogmf.2019.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677278PMC
March 2019

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.

Nat Genet 2019 01 26;51(1):63-75. Epub 2018 Nov 26.

Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://www.nature.com/articles/s41588-018-0269-7
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http://dx.doi.org/10.1038/s41588-018-0269-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481311PMC
January 2019

Reduction in non-abstinent WHO drinking risk levels and depression/anxiety disorders: 3-year follow-up results in the US general population.

Drug Alcohol Depend 2019 04 14;197:228-235. Epub 2019 Feb 14.

Columbia University Mailman School of Public Health, 722 West 168th Street, New York, NY 10032, USA; New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440807PMC
April 2019

Risk Locus Identification Ties Alcohol Withdrawal Symptoms to SORCS2.

Alcohol Clin Exp Res 2018 12 25;42(12):2337-2348. Epub 2018 Oct 25.

Department of Psychiatry , Division of Human Genetics, VA CT Healthcare Center, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1111/acer.13890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317871PMC
December 2018

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Authors:
Raymond K Walters Renato Polimanti Emma C Johnson Jeanette N McClintick Mark J Adams Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Yi-Ling Chou Franziska Degenhardt Anna R Docherty Alexis C Edwards Pierre Fontanillas Jerome C Foo Louis Fox Josef Frank Ina Giegling Scott Gordon Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Stefan Herms Colin Hodgkinson Per Hoffmann Jouke Jan Hottenga Martin A Kennedy Mervi Alanne-Kinnunen Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen John F Pearson Roseann E Peterson Samuli Ripatti Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Sarah L Elson Mark A Frye Wolfgang Gäbel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Aarno Palotie Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie Witt Norbert Wodarz Peter Zill Daniel E Adkins Joseph M Boden Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz Sven Cichon E Jane Costello Harriet de Wit Nancy Diazgranados Danielle M Dick Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William Iacono Eric O Johnson Jaakko A Kaprio Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Paul Lichtenstein Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik Magnusson Nicholas G Martin Sarah E Medland Grant W Montgomery Elliot C Nelson Markus M Nöthen Abraham A Palmer Nancy L Pedersen Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard Rose Dan Rujescu Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Joel Gelernter Howard J Edenberg Arpana Agrawal

Nat Neurosci 2018 12 26;21(12):1656-1669. Epub 2018 Nov 26.

Washington University School of Medicine, Department of Psychiatry, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41593-018-0275-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430207PMC
December 2018

Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.

Biol Psychiatry 2018 11 11;84(10):762-770. Epub 2018 Jan 11.

Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, Massachusetts; Departments of Genetics and Neuroscience, Yale University School of Medicine, New Haven, Massachusetts; VA Connecticut Healthcare Center, West Haven, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2017.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041180PMC
November 2018

Predictors of Treatment Referral after AUDIT-C Screening for Heavy Drinking.

Addict Disord Their Treat 2018 Sep;17(3):124-133

Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://Insights.ovid.com/crossref?an=00132576-201809000-0000
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http://dx.doi.org/10.1097/ADT.0000000000000134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159906PMC
September 2018

Topiramate versus naltrexone for alcohol use disorder: study protocol for a genotype-stratified, double-blind randomised controlled trial (TOP study).

Trials 2018 Aug 16;19(1):443. Epub 2018 Aug 16.

University of Sydney, Faculty of Medicine and Health, Central Clinical School, NHMRC Centre of Research Excellence in Mental Health and Substance Use, Sydney, NSW, Australia.

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https://trialsjournal.biomedcentral.com/articles/10.1186/s13
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http://dx.doi.org/10.1186/s13063-018-2824-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097336PMC
August 2018

Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review.

JAMA 2018 08;320(8):815-824

Department of Psychiatry, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1001/jama.2018.11406DOI Listing
August 2018

Opioid Misuse as a Predictor of Alcohol Treatment Outcomes in the COMBINE Study: Mediation by Medication Adherence.

Alcohol Clin Exp Res 2018 07 9;42(7):1249-1259. Epub 2018 Jun 9.

Center for Studies of Addiction, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/acer.13772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063524PMC
July 2018

Genome-wide association study of cognitive flexibility assessed by the Wisconsin Card Sorting Test.

Am J Med Genet B Neuropsychiatr Genet 2018 07;177(5):511-519

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1002/ajmg.b.32642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110090PMC
July 2018

Meta-Analysis of the Association of Alcohol-Related Social Media Use with Alcohol Consumption and Alcohol-Related Problems in Adolescents and Young Adults.

Alcohol Clin Exp Res 2018 06 22;42(6):978-986. Epub 2018 May 22.

Department of Psychiatry , Perelman School of Medicine, Center for Studies of Addiction, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://doi.wiley.com/10.1111/acer.13642
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http://dx.doi.org/10.1111/acer.13642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984178PMC
June 2018

Examining the effects of alcohol on GABA receptor mRNA expression and function in neural cultures generated from control and alcohol dependent donor induced pluripotent stem cells.

Alcohol 2018 02 12;66:45-53. Epub 2017 Aug 12.

Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT, 06030-1410, USA; Institute for Systems Genomics, University of Connecticut, Storrs, CT, 06268, USA. Electronic address:

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http://dx.doi.org/10.1016/j.alcohol.2017.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743620PMC
February 2018

Precision medicine and pharmacogenetics: what does oncology have that addiction medicine does not?

Addiction 2017 Dec 21;112(12):2086-2094. Epub 2017 Apr 21.

Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/add.13818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650957PMC
December 2017

Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.

Am J Med Genet B Neuropsychiatr Genet 2017 Dec 9;174(8):846-853. Epub 2017 Oct 9.

Department of Psychiatry, Yale University School of Medicine, West Haven, Connecticut.

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http://dx.doi.org/10.1002/ajmg.b.32604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861711PMC
December 2017

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

JAMA Psychiatry 2017 12;74(12):1234-1241

Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1001/jamapsychiatry.2017.3275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331050PMC
December 2017

Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study.

J Psychiatr Res 2017 11 8;94:139-147. Epub 2017 Jul 8.

U.S. Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, CT, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1016/j.jpsychires.2017.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605420PMC
November 2017

Collaborative Phenotype Inference from Comorbid Substance Use Disorders and Genotypes.

Proceedings (IEEE Int Conf Bioinformatics Biomed) 2017 Nov 18;2017:392-397. Epub 2017 Dec 18.

Department of Computer Science and Engineering, University of Connecticut, Storrs, Connecticut.

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http://dx.doi.org/10.1109/BIBM.2017.8217681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947969PMC
November 2017

Effects of Recent Alcohol Consumption Level on Neurocognitive Performance in HIV+ Individuals.

Addict Disord Their Treat 2017 Sep;16(3):95-107

Behavioral Health Service, Crescenz VAMC, 3900 Woodland Ave., Philadelphia, PA 19104.

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http://dx.doi.org/10.1097/ADT.0000000000000109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654614PMC
September 2017

identified in a genome-wide gene × cannabis dependence interaction analysis of risky sexual behaviours.

J Psychiatry Neurosci 2017 06;42(4):252-261

From the Department of Psychiatry, Yale University School of Medicine and VA CT Healthcare Center, West Haven, Conn., USA (Polimanti, Pearlson, Gelernter); Olin Research Center, Institute of Living/Hartford Hospital, Hartford, Conn., USA (Meda, Pearlson); the Department of Neuroscience, Yale University School of Medicine, New Haven, Conn., USA (Pearlson, Gelernter); the Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Mass., USA (Sherva, Farrer); the Department of Biostatistics, Yale University School of Public Health, New Haven, Conn., USA (Zhao); the Department of Genetics, Yale University School of Medicine, New Haven, Conn., USA (Zhao, Gelernter); the Departments of Neurology, Ophthalmology, Biostatistics, and Epidemiology, Boston University Schools of Medicine and Public Health, Boston, Mass., USA (Farrer); and the Department of Psychiatry, University of Pennsylvania School of Medicine and VISN 4 MIRECC, Crescenz VAMC, Philadelphia, Pa., USA (Kranzler).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487272PMC
June 2017

Temporal Stability of Heavy Drinking Days and Drinking Reductions Among Heavy Drinkers in the COMBINE Study.

Alcohol Clin Exp Res 2017 May 5;41(5):1054-1062. Epub 2017 Apr 5.

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina.

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http://dx.doi.org/10.1111/acer.13371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404970PMC
May 2017

Validating Harmful Alcohol Use as a Phenotype for Genetic Discovery Using Phosphatidylethanol and a Polymorphism in ADH1B.

Alcohol Clin Exp Res 2017 May 10;41(5):998-1003. Epub 2017 Apr 10.

Department of Psychiatry, University of Pennsylvania Perelman School of Medicine and VISN 4 MIRECC, Crescenz VAMC, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/acer.13373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501250PMC
May 2017

Correlates of Electronic Cigarettes Use Before and During Pregnancy.

Nicotine Tob Res 2017 May;19(5):585-590

Department of Obstetrics and Gynecology, Baystate Medical Center, Springfield, MA.

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http://dx.doi.org/10.1093/ntr/ntw225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896457PMC
May 2017

Sex-specific linkage scans in opioid dependence.

Am J Med Genet B Neuropsychiatr Genet 2017 Apr 20;174(3):261-268. Epub 2016 Oct 20.

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1002/ajmg.b.32507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695218PMC
April 2017

Genome-wide association study of body mass index in subjects with alcohol dependence.

Addict Biol 2017 Mar 12;22(2):535-549. Epub 2015 Oct 12.

Department of Psychiatry, Yale University School of Medicine and VA CT Healthcare Center, West Haven, CT, USA.

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http://dx.doi.org/10.1111/adb.12317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5102811PMC
March 2017

Guidelines for biological treatment of substance use and related disorders, part 1: Alcoholism, first revision.

World J Biol Psychiatry 2017 03 23;18(2):86-119. Epub 2016 Dec 23.

b Department of Psychiatry , Ludwig-Maximilians-University , Munich , Germany.

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http://dx.doi.org/10.1080/15622975.2016.1246752DOI Listing
March 2017

The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene.

Neuropsychopharmacology 2017 02 17;42(3):598-605. Epub 2016 Aug 17.

Department of Psychiatry, Yale University School of Medicine and VA CT Healthcare Center, West Haven, CT, USA.

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http://dx.doi.org/10.1038/npp.2016.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240175PMC
February 2017

Effects of LY466195, a selective kainate receptor antagonist, on ethanol preference and drinking in rats.

Neurosci Lett 2017 02 21;639:8-12. Epub 2016 Dec 21.

Center for Neurobiology and Behavior, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; Department of Biobehavioral Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2016.12.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5272788PMC
February 2017

Alcohol and nicotine codependence-associated DNA methylation changes in promoter regions of addiction-related genes.

Sci Rep 2017 02 6;7:41816. Epub 2017 Feb 6.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/srep41816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292964PMC
February 2017

Urgency traits moderate daily relations between affect and drinking to intoxication among young adults.

Drug Alcohol Depend 2017 Jan 3;170:59-65. Epub 2016 Nov 3.

Yale School of Medicine, Department of Psychiatry, New Haven, CT, United States; Yale Cancer Center, New Haven, CT, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2016.10.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183550PMC
January 2017

Examining FKBP5 mRNA expression in human iPSC-derived neural cells.

Psychiatry Res 2017 Jan 24;247:172-181. Epub 2016 Nov 24.

Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington 06030-1410, CT, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01651781163116
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http://dx.doi.org/10.1016/j.psychres.2016.11.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191911PMC
January 2017

Phenome-Wide Association Study for Alcohol and Nicotine Risk Alleles in 26394 Women.

Neuropsychopharmacology 2016 10 17;41(11):2688-96. Epub 2016 May 17.

Department of Psychiatry, Yale School of Medicine, West Haven, CT, USA.

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http://dx.doi.org/10.1038/npp.2016.72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026736PMC
October 2016

FKBP5 genotype interacts with early life trauma to predict heavy drinking in college students.

Am J Med Genet B Neuropsychiatr Genet 2016 09 19;171(6):879-87. Epub 2016 May 19.

Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut.

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http://doi.wiley.com/10.1002/ajmg.b.32460
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045724PMC
http://dx.doi.org/10.1002/ajmg.b.32460DOI Listing
September 2016

Reductions in Alcohol Craving Following Naltrexone Treatment for Heavy Drinking.

Alcohol Alcohol 2016 Sep 11;51(5):562-6. Epub 2016 Jul 11.

VISN 4 MIRECC, Corporal Michael Crescenz VAMC Center for Studies of Addiction, University of Pennsylvania Perelman School of Medicine.

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http://dx.doi.org/10.1093/alcalc/agw038DOI Listing
September 2016

Which alcohol use disorder criteria contribute to the association of ADH1B with alcohol dependence?

Addict Biol 2016 07 1;21(4):924-38. Epub 2015 Apr 1.

Center for Studies of Addiction, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/adb.12244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591076PMC
July 2016

Missing Data in Alcohol Clinical Trials with Binary Outcomes.

Alcohol Clin Exp Res 2016 07 2;40(7):1548-57. Epub 2016 Jun 2.

Department of Psychiatry, Addiction Sciences Division, Medical University of South Carolina, Charleston, South Carolina.

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http://dx.doi.org/10.1111/acer.13106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522809PMC
July 2016

An Effective Method to Identify Heritable Components from Multivariate Phenotypes.

PLoS One 2015 14;10(12):e0144418. Epub 2015 Dec 14.

Department of Computer Science and Engineering, University of Connecticut, Storrs, Connecticut, United States of America.

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http://www.engr.uconn.edu/~jinbo/doc/journal.pone.0144418.pd
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http://dx.plos.org/10.1371/journal.pone.0144418
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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0144418PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678282PMC
June 2016

New Initiatives for Alcoholism: Clinical and Experimental Research.

Authors:
Henry R Kranzler

Alcohol Clin Exp Res 2016 Apr 24;40(4):652. Epub 2016 Feb 24.

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http://dx.doi.org/10.1111/acer.13018DOI Listing
April 2016

Self-efficacy mediates the effects of topiramate and GRIK1 genotype on drinking.

Addict Biol 2016 Mar 15;21(2):450-9. Epub 2014 Dec 15.

Center for Studies of Addiction, Department of Psychiatry, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/adb.12207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468044PMC
March 2016

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts.

Authors:
Tae-Hwi Schwantes-An Juan Zhang Li-Shiun Chen Sarah M Hartz Robert C Culverhouse Xiangning Chen Hilary Coon Josef Frank Helen M Kamens Bettina Konte Leena Kovanen Antti Latvala Lisa N Legrand Brion S Maher Whitney E Melroy Elliot C Nelson Mark W Reid Jason D Robinson Pei-Hong Shen Bao-Zhu Yang Judy A Andrews Paul Aveyard Olga Beltcheva Sandra A Brown Dale S Cannon Sven Cichon Robin P Corley Norbert Dahmen Louisa Degenhardt Tatiana Foroud Wolfgang Gaebel Ina Giegling Stephen J Glatt Richard A Grucza Jill Hardin Annette M Hartmann Andrew C Heath Stefan Herms Colin A Hodgkinson Per Hoffmann Hyman Hops David Huizinga Marcus Ising Eric O Johnson Elaine Johnstone Radka P Kaneva Kenneth S Kendler Falk Kiefer Henry R Kranzler Ken S Krauter Orna Levran Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Nicholas G Martin Manuel Mattheisen Grant W Montgomery Bertram Müller-Myhsok Michael F Murphy Michael C Neale Momchil A Nikolov Denise Nishita Markus M Nöthen John Nurnberger Timo Partonen Michele L Pergadia Maureen Reynolds Monika Ridinger Richard J Rose Noora Rouvinen-Lagerström Norbert Scherbaum Christine Schmäl Michael Soyka Michael C Stallings Michael Steffens Jens Treutlein Ming Tsuang Tamara L Wall Norbert Wodarz Vadim Yuferov Peter Zill Andrew W Bergen Jingchun Chen Paul M Cinciripini Howard J Edenberg Marissa A Ehringer Robert E Ferrell Joel Gelernter David Goldman John K Hewitt Christian J Hopfer William G Iacono Jaakko Kaprio Mary Jeanne Kreek Ivo M Kremensky Pamela A F Madden Matt McGue Marcus R Munafò Robert A Philibert Marcella Rietschel Alec Roy Dan Rujescu Sirkku T Saarikoski Gary E Swan Alexandre A Todorov Michael M Vanyukov Robert B Weiss Laura J Bierut Nancy L Saccone

Behav Genet 2016 Mar 21;46(2):151-69. Epub 2015 Sep 21.

Department of Genetics, Washington University School of Medicine, 4523 Clayton Avenue, Campus Box 8232, St. Louis, MO, 63110, USA.

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http://link.springer.com/10.1007/s10519-015-9737-3
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http://dx.doi.org/10.1007/s10519-015-9737-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752855PMC
March 2016

Balancing risk and benefit in heavy drinkers treated with topiramate: implications for personalized care.

J Clin Psychiatry 2016 Mar;77(3):e278-82

Department of Medical Sciences, Frank Netter School of Medicine, Quinnipiac University, Hamden, Connecticut.

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http://dx.doi.org/10.4088/JCP.15m10053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845738PMC
March 2016

Genetic Vulnerability to Menthol Cigarette Preference in Women.

Nicotine Tob Res 2015 Dec 1;17(12):1416-20. Epub 2015 Apr 1.

Department of Obstetrics and Gynecology, Baystate Medical Center, Springfield, MA.

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https://academic.oup.com/ntr/article-lookup/doi/10.1093/ntr/
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http://dx.doi.org/10.1093/ntr/ntv042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013875PMC
December 2015

Further analyses support the association between light eye color and alcohol dependence.

Am J Med Genet B Neuropsychiatr Genet 2015 Dec 20;168(8):757-60. Epub 2015 Aug 20.

Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont.

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http://dx.doi.org/10.1002/ajmg.b.32357DOI Listing
December 2015

Smoking and Cellular Telephone Use Among Pregnant Women Seeking Prenatal Care: Opportunities for Intervention.

Addict Disord Their Treat 2015 Dec 29;14(4):203-210. Epub 2014 May 29.

Treatment Research Center, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104; Philadelphia VAMC, Philadelphia, PA 19104.

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http://dx.doi.org/10.1097/ADT.0000000000000053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705558PMC
December 2015

Insomnia in alcohol dependent subjects is associated with greater psychosocial problem severity.

Addict Behav 2015 Nov 20;50:165-72. Epub 2015 Jun 20.

Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA 19104, United States; Philadelphia Veterans Affairs Medical Center, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.addbeh.2015.06.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515378PMC
November 2015

Endorsement of the CONSORT Principles in Reporting Alcohol Clinical Trials in ACER.

Authors:
Henry R Kranzler

Alcohol Clin Exp Res 2015 Sep 24;39(9):1556. Epub 2015 Jul 24.

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http://doi.wiley.com/10.1111/acer.12830
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September 2015

Recommendations for the Design and Analysis of Treatment Trials for Alcohol Use Disorders.

Alcohol Clin Exp Res 2015 Sep 6;39(9):1557-70. Epub 2015 Aug 6.

Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/acer.12800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558228PMC
September 2015

GABRA2 Alcohol Dependence Risk Allele is Associated with Reduced Expression of Chromosome 4p12 GABAA Subunit Genes in Human Neural Cultures.

Alcohol Clin Exp Res 2015 Sep 6;39(9):1654-64. Epub 2015 Aug 6.

Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut.

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http://doi.wiley.com/10.1111/acer.12807
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558268PMC
September 2015

Guidelines for the Reporting of Treatment Trials for Alcohol Use Disorders.

Alcohol Clin Exp Res 2015 Sep 11;39(9):1571-81. Epub 2015 Aug 11.

Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/acer.12797DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558296PMC
September 2015

Inter-observer reliability of DSM-5 substance use disorders.

Drug Alcohol Depend 2015 Aug 27;153:229-35. Epub 2015 May 27.

Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, United States; VISN4 MIRECC, Philadelphia VAMC, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2015.05.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4509850PMC
August 2015

Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses.

Alcohol Clin Exp Res 2015 Aug 25;39(8):1312-27. Epub 2015 Jun 25.

Center for Studies of Addiction, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://doi.wiley.com/10.1111/acer.12792
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http://dx.doi.org/10.1111/acer.12792DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4515198PMC
August 2015

Eye color: A potential indicator of alcohol dependence risk in European Americans.

Am J Med Genet B Neuropsychiatr Genet 2015 Jul 29;168B(5):347-53. Epub 2015 Apr 29.

Department of Microbiology and Molecular Genetics, University of Vermont, Burlington, Vermont.

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http://dx.doi.org/10.1002/ajmg.b.32316DOI Listing
July 2015

Subgroup Identification in Personalized Treatment of Alcohol Dependence.

Alcohol Clin Exp Res 2015 Jul 29;39(7):1253-9. Epub 2015 May 29.

Department of Preventive Medicine, Northwestern University, Chicago, Illinois.

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http://dx.doi.org/10.1111/acer.12759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4491003PMC
July 2015

Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans.

Alcohol Clin Exp Res 2015 Jul 3;39(7):1137-47. Epub 2015 Jun 3.

Department of Psychiatry, Yale School of Medicine, and VA CT Healthcare Center, West Haven, Connecticut.

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http://dx.doi.org/10.1111/acer.12751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706077PMC
July 2015

Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans.

Biol Psychiatry 2015 Mar 16;77(5):493-503. Epub 2014 Sep 16.

Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Massachusetts; Departments of Neurology, Ophthalmology, Genetics and Genomics, and Epidemiology and Biostatistics, Boston University Schools of Medicine and Public Health, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.biopsych.2014.08.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4386684PMC
March 2015

The pharmacogenetics of alcohol use disorder.

Alcohol Clin Exp Res 2015 Mar 19;39(3):391-402. Epub 2015 Feb 19.

Division on Substance Abuse , New York State Psychiatric Institute & Columbia University College of Physicians and Surgeons, New York, New York.

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http://dx.doi.org/10.1111/acer.12643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348335PMC
March 2015

GRIK1 genotype and daily expectations of alcohol's positive effects moderate the reduction of heavy drinking by topiramate.

Exp Clin Psychopharmacol 2014 Dec;22(6):494-501

Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine.

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http://dx.doi.org/10.1037/a0038350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4251491PMC
December 2014

Posttreatment effects of topiramate treatment for heavy drinking.

Alcohol Clin Exp Res 2014 Dec;38(12):3017-23

Department of Psychiatry, Center for Studies of Addiction, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania; VISN4 MIRECC, Philadelphia VAMC, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/acer.12578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293099PMC
December 2014