Publications by authors named "Henry R Kranzler"

98Publications

Reduction in World Health Organization Risk Drinking Levels and Cardiovascular Disease.

Alcohol Clin Exp Res 2020 Aug 3;44(8):1625-1635. Epub 2020 Jul 3.

Columbia University Mailman School of Public Health, New York, New York.

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http://dx.doi.org/10.1111/acer.14386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7484295PMC
August 2020

Molecular Correlates of Topiramate and GRIK1 rs2832407 Genotype in Pluripotent Stem Cell-Derived Neural Cultures.

Alcohol Clin Exp Res 2020 Aug 9;44(8):1561-1570. Epub 2020 Aug 9.

From the, Alcohol Research Center, (RL, KC, JC), Department of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut, USA.

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http://dx.doi.org/10.1111/acer.14399DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7491603PMC
August 2020

Pregnant Smokers Receiving Opioid Agonist Therapy Have an Elevated Nicotine Metabolite Ratio: A Replication Study.

Nicotine Tob Res 2020 Apr 18. Epub 2020 Apr 18.

Center for Interdisciplinary Research on Nicotine Addiction, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1093/ntr/ntaa066DOI Listing
April 2020

Survey of Addiction Specialists' Use of Medications to Treat Alcohol Use Disorder.

Front Psychiatry 2020 14;11:47. Epub 2020 Feb 14.

Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States.

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http://dx.doi.org/10.3389/fpsyt.2020.00047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7034336PMC
February 2020

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.

Authors:
Melissa A Munn-Chernoff Emma C Johnson Yi-Ling Chou Jonathan R I Coleman Laura M Thornton Raymond K Walters Zeynep Yilmaz Jessica H Baker Christopher Hübel Scott Gordon Sarah E Medland Hunna J Watson Héléna A Gaspar Julien Bryois Anke Hinney Virpi M Leppä Manuel Mattheisen Stephan Ripke Shuyang Yao Paola Giusti-Rodríguez Ken B Hanscombe Roger A H Adan Lars Alfredsson Tetsuya Ando Ole A Andreassen Wade H Berrettini Ilka Boehm Claudette Boni Vesna Boraska Perica Katharina Buehren Roland Burghardt Matteo Cassina Sven Cichon Maurizio Clementi Roger D Cone Philippe Courtet Scott Crow James J Crowley Unna N Danner Oliver S P Davis Martina de Zwaan George Dedoussis Daniela Degortes Janiece E DeSocio Danielle M Dick Dimitris Dikeos Christian Dina Monika Dmitrzak-Weglarz Elisa Docampo Laramie E Duncan Karin Egberts Stefan Ehrlich Geòrgia Escaramís Tõnu Esko Xavier Estivill Anne Farmer Angela Favaro Fernando Fernández-Aranda Manfred M Fichter Krista Fischer Manuel Föcker Lenka Foretova Andreas J Forstner Monica Forzan Christopher S Franklin Steven Gallinger Ina Giegling Johanna Giuranna Fragiskos Gonidakis Philip Gorwood Monica Gratacos Mayora Sébastien Guillaume Yiran Guo Hakon Hakonarson Konstantinos Hatzikotoulas Joanna Hauser Johannes Hebebrand Sietske G Helder Stefan Herms Beate Herpertz-Dahlmann Wolfgang Herzog Laura M Huckins James I Hudson Hartmut Imgart Hidetoshi Inoko Vladimir Janout Susana Jiménez-Murcia Antonio Julià Gursharan Kalsi Deborah Kaminská Leila Karhunen Andreas Karwautz Martien J H Kas James L Kennedy Anna Keski-Rahkonen Kirsty Kiezebrink Youl-Ri Kim Kelly L Klump Gun Peggy S Knudsen Maria C La Via Stephanie Le Hellard Robert D Levitan Dong Li Lisa Lilenfeld Bochao Danae Lin Jolanta Lissowska Jurjen Luykx Pierre J Magistretti Mario Maj Katrin Mannik Sara Marsal Christian R Marshall Morten Mattingsdal Sara McDevitt Peter McGuffin Andres Metspalu Ingrid Meulenbelt Nadia Micali Karen Mitchell Alessio Maria Monteleone Palmiero Monteleone Benedetta Nacmias Marie Navratilova Ioanna Ntalla Julie K O'Toole Roel A Ophoff Leonid Padyukov Aarno Palotie Jacques Pantel Hana Papezova Dalila Pinto Raquel Rabionet Anu Raevuori Nicolas Ramoz Ted Reichborn-Kjennerud Valdo Ricca Samuli Ripatti Franziska Ritschel Marion Roberts Alessandro Rotondo Dan Rujescu Filip Rybakowski Paolo Santonastaso André Scherag Stephen W Scherer Ulrike Schmidt Nicholas J Schork Alexandra Schosser Jochen Seitz Lenka Slachtova P Eline Slagboom Margarita C T Slof-Op't Landt Agnieszka Slopien Sandro Sorbi Beata Świątkowska Jin P Szatkiewicz Ioanna Tachmazidou Elena Tenconi Alfonso Tortorella Federica Tozzi Janet Treasure Artemis Tsitsika Marta Tyszkiewicz-Nwafor Konstantinos Tziouvas Annemarie A van Elburg Eric F van Furth Gudrun Wagner Esther Walton Elisabeth Widen Eleftheria Zeggini Stephanie Zerwas Stephan Zipfel Andrew W Bergen Joseph M Boden Harry Brandt Steven Crawford Katherine A Halmi L John Horwood Craig Johnson Allan S Kaplan Walter H Kaye James Mitchell Catherine M Olsen John F Pearson Nancy L Pedersen Michael Strober Thomas Werge David C Whiteman D Blake Woodside Jakob Grove Anjali K Henders Janne T Larsen Richard Parker Liselotte V Petersen Jennifer Jordan Martin A Kennedy Andreas Birgegård Paul Lichtenstein Claes Norring Mikael Landén Preben Bo Mortensen Renato Polimanti Jeanette N McClintick Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Franziska Degenhardt Anna R Docherty Alexis C Edwards Jerome C Foo Louis Fox Josef Frank Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Colin Hodgkinson Per Hoffmann Jouke-Jan Hottenga Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen Roseann E Peterson Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Hang Zhou Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Mark A Frye Wolfgang Gäebel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer Gabriele Koller John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie H Witt Norbert Wodarz Peter Zill Daniel E Adkins Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz E Jane Costello Harriet de Wit Nancy Diazgranados Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Victor Hesselbrock John K Hewitt Christian J Hopfer William G Iacono Eric O Johnson Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik K E Magnusson Elliot C Nelson Markus M Nöthen Abraham A Palmer Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard J Rose Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Tracey D Wade Andrew C Heath Grant W Montgomery Nicholas G Martin Patrick F Sullivan Jaakko Kaprio Gerome Breen Joel Gelernter Howard J Edenberg Cynthia M Bulik Arpana Agrawal

Addict Biol 2020 Feb 16:e12880. Epub 2020 Feb 16.

Department of Psychiatry, Washington University School of Medicine, Saint Louis, Missouri, USA.

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http://dx.doi.org/10.1111/adb.12880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7429266PMC
February 2020

Genome-Wide Association Study of Opioid Cessation.

J Clin Med 2020 Jan 9;9(1). Epub 2020 Jan 9.

Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA 02118, USA.

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http://dx.doi.org/10.3390/jcm9010180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019731PMC
January 2020

Author Correction: Genomewide Study of Epigenetic Biomarkers of Opioid Dependence in European- American Women.

Sci Rep 2019 Dec 5;9(1):18774. Epub 2019 Dec 5.

Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41598-019-55022-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892860PMC
December 2019

Genomewide Gene-by-Sex Interaction Scans Identify ADGRV1 for Sex Differences in Opioid Dependent African Americans.

Sci Rep 2019 12 2;9(1):18070. Epub 2019 Dec 2.

Yale University School of Medicine, Department of Psychiatry, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41598-019-53560-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889277PMC
December 2019

Post-GWAS analysis of six substance use traits improves the identification and functional interpretation of genetic risk loci.

Drug Alcohol Depend 2020 01 4;206:107703. Epub 2019 Nov 4.

Department of Psychiatry, Amsterdam UMC, Amsterdam Neuroscience, University of Amsterdam, Meibergdreef 9, Amsterdam, the Netherlands; QIMR Berghofer, Translational Neurogenomics group, Brisbane, Australia.

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http://dx.doi.org/10.1016/j.drugalcdep.2019.107703DOI Listing
January 2020

A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans.

Transl Psychiatry 2019 11 18;9(1):309. Epub 2019 Nov 18.

Division of Human Genetics, Department of Psychiatry, VA CT Healthcare Center, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/s41398-019-0639-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861240PMC
November 2019

Long-term use of hydrocodone vs. oxycodone in primary care.

Drug Alcohol Depend 2019 12 2;205:107524. Epub 2019 Nov 2.

Department of Medicine, Infectious Diseases, Department of Epidemiology, Biostatistics, Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2019.06.026DOI Listing
December 2019

Prevention, screening, and treatment for heavy drinking and alcohol use disorder.

Lancet Psychiatry 2019 12 17;6(12):1054-1067. Epub 2019 Oct 17.

Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Mental Illness Research, Education and Clinical Center, Veterans Integrated Service Network 4, Corporal Michael J Crescenz Veterans Affairs Medical Center, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/S2215-0366(19)30213-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883141PMC
December 2019

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.

Authors:
Caroline M Nievergelt Adam X Maihofer Torsten Klengel Elizabeth G Atkinson Chia-Yen Chen Karmel W Choi Jonathan R I Coleman Shareefa Dalvie Laramie E Duncan Joel Gelernter Daniel F Levey Mark W Logue Renato Polimanti Allison C Provost Andrew Ratanatharathorn Murray B Stein Katy Torres Allison E Aiello Lynn M Almli Ananda B Amstadter Søren B Andersen Ole A Andreassen Paul A Arbisi Allison E Ashley-Koch S Bryn Austin Esmina Avdibegovic Dragan Babić Marie Bækvad-Hansen Dewleen G Baker Jean C Beckham Laura J Bierut Jonathan I Bisson Marco P Boks Elizabeth A Bolger Anders D Børglum Bekh Bradley Megan Brashear Gerome Breen Richard A Bryant Angela C Bustamante Jonas Bybjerg-Grauholm Joseph R Calabrese José M Caldas-de-Almeida Anders M Dale Mark J Daly Nikolaos P Daskalakis Jürgen Deckert Douglas L Delahanty Michelle F Dennis Seth G Disner Katharina Domschke Alma Dzubur-Kulenovic Christopher R Erbes Alexandra Evans Lindsay A Farrer Norah C Feeny Janine D Flory David Forbes Carol E Franz Sandro Galea Melanie E Garrett Bizu Gelaye Elbert Geuze Charles Gillespie Aferdita Goci Uka Scott D Gordon Guia Guffanti Rasha Hammamieh Supriya Harnal Michael A Hauser Andrew C Heath Sian M J Hemmings David Michael Hougaard Miro Jakovljevic Marti Jett Eric Otto Johnson Ian Jones Tanja Jovanovic Xue-Jun Qin Angela G Junglen Karen-Inge Karstoft Milissa L Kaufman Ronald C Kessler Alaptagin Khan Nathan A Kimbrel Anthony P King Nastassja Koen Henry R Kranzler William S Kremen Bruce R Lawford Lauren A M Lebois Catrin E Lewis Sarah D Linnstaedt Adriana Lori Bozo Lugonja Jurjen J Luykx Michael J Lyons Jessica Maples-Keller Charles Marmar Alicia R Martin Nicholas G Martin Douglas Maurer Matig R Mavissakalian Alexander McFarlane Regina E McGlinchey Katie A McLaughlin Samuel A McLean Sarah McLeay Divya Mehta William P Milberg Mark W Miller Rajendra A Morey Charles Phillip Morris Ole Mors Preben B Mortensen Benjamin M Neale Elliot C Nelson Merete Nordentoft Sonya B Norman Meaghan O'Donnell Holly K Orcutt Matthew S Panizzon Edward S Peters Alan L Peterson Matthew Peverill Robert H Pietrzak Melissa A Polusny John P Rice Stephan Ripke Victoria B Risbrough Andrea L Roberts Alex O Rothbaum Barbara O Rothbaum Peter Roy-Byrne Ken Ruggiero Ariane Rung Bart P F Rutten Nancy L Saccone Sixto E Sanchez Dick Schijven Soraya Seedat Antonia V Seligowski Julia S Seng Christina M Sheerin Derrick Silove Alicia K Smith Jordan W Smoller Scott R Sponheim Dan J Stein Jennifer S Stevens Jennifer A Sumner Martin H Teicher Wesley K Thompson Edward Trapido Monica Uddin Robert J Ursano Leigh Luella van den Heuvel Miranda Van Hooff Eric Vermetten Christiaan H Vinkers Joanne Voisey Yunpeng Wang Zhewu Wang Thomas Werge Michelle A Williams Douglas E Williamson Sherry Winternitz Christiane Wolf Erika J Wolf Jonathan D Wolff Rachel Yehuda Ross McD Young Keith A Young Hongyu Zhao Lori A Zoellner Israel Liberzon Kerry J Ressler Magali Haas Karestan C Koenen

Nat Commun 2019 10 8;10(1):4558. Epub 2019 Oct 8.

Broad Institute of MIT and Harvard, Stanley Center for Psychiatric Research, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41467-019-12576-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6783435PMC
October 2019

A genome-wide association study of cocaine use disorder accounting for phenotypic heterogeneity and gene–environment interaction

J Psychiatry Neurosci 2020 01;45(1):34-44

From the Department of Computer Science and Engineering, University of Connecticut, School of Engineering, Storrs, CT (Sun, Bi); the University of Pennsylvania Perelman School of Medicine, Department of Psychiatry, Center for Studies of Addiction and Corporal Michael Crescenz VAMC, Philadelphia, PA (Kranzler); and the Yale University School of Medicine, Department of Psychiatry, Division of Human Genetics and Departments of Genetics and Neurobiology; and VA CT Healthcare Center, New Haven, CT (Gelernter).

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http://dx.doi.org/10.1503/jpn.180098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6919916PMC
January 2020

Advancing Precision Medicine for Alcohol Use Disorder: Replication and Extension of Reward Drinking as a Predictor of Naltrexone Response.

Alcohol Clin Exp Res 2019 11 11;43(11):2395-2405. Epub 2019 Sep 11.

Department of Psychiatry, Perelman School of Medicine and Crescenz Veterans Affairs Medical Center, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/acer.14183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824945PMC
November 2019

Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study.

Depress Anxiety 2019 09 6;36(9):834-845. Epub 2019 Aug 6.

U.S. Department of Veterans Affairs National Center for PTSD, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, Connecticut.

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http://dx.doi.org/10.1002/da.22912DOI Listing
September 2019

Randomized Trial of Nicotine Inhaler for Pregnant Smokers.

Am J Obstet Gynecol MFM 2019 Mar 27;1(1):10-18. Epub 2019 Mar 27.

Department of Medicine, University of Connecticut School of Medicine, Farmington, CT.

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http://dx.doi.org/10.1016/j.ajogmf.2019.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6677278PMC
March 2019

Genome-wide scan identifies opioid overdose risk locus close to MCOLN1.

Addict Biol 2020 03 30;25(2):e12811. Epub 2019 Jul 30.

Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine and VA CT Healthcare Center, New Haven, CT, USA.

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http://dx.doi.org/10.1111/adb.12811DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7485539PMC
March 2020

Reduction in non-abstinent World Health Organization (WHO) drinking risk levels and drug use disorders: 3-year follow-up results in the US general population.

Drug Alcohol Depend 2019 08 29;201:16-22. Epub 2019 May 29.

Columbia University Mailman School of Public Health, 722 West 168th Street, New York, NY, 10032, USA; New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY, 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2019.03.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662197PMC
August 2019

Pharmacogenetics of alcohol use disorder treatments: an update.

Expert Opin Drug Metab Toxicol 2019 Jul 11;15(7):553-564. Epub 2019 Jun 11.

a Mental Illness Research, Education and Clinical Center , Crescenz VAMC , Philadelphia , PA , USA.

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http://dx.doi.org/10.1080/17425255.2019.1628218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614002PMC
July 2019

A meta-analysis of the efficacy of gabapentin for treating alcohol use disorder.

Addiction 2019 09 5;114(9):1547-1555. Epub 2019 Jun 5.

Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/add.14655DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682454PMC
September 2019

Opioid Use and Rate of Nicotine Metabolism Among Pregnant Smokers.

Nicotine Tob Res 2020 05;22(6):1046-1050

Department of Medicine, University of Connecticut School of Medicine, Farmington, CT.

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http://dx.doi.org/10.1093/ntr/ntz073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7249922PMC
May 2020

Cognitive Behavioral Therapy for Insomnia in Alcohol-Dependent Veterans: A Randomized, Controlled Pilot Study.

Alcohol Clin Exp Res 2019 06 29;43(6):1244-1253. Epub 2019 Apr 29.

Corporal Michael J. Crescenz VA Medical Center , Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/acer.14030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551284PMC
June 2019

Genomewide Study of Epigenetic Biomarkers of Opioid Dependence in European- American Women.

Sci Rep 2019 03 15;9(1):4660. Epub 2019 Mar 15.

Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.

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http://www.nature.com/articles/s41598-019-41110-7
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http://dx.doi.org/10.1038/s41598-019-41110-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420601PMC
March 2019

Alcohol-responsive genes identified in human iPSC-derived neural cultures.

Transl Psychiatry 2019 03 12;9(1):96. Epub 2019 Mar 12.

Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT, 06030-1410, USA.

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http://dx.doi.org/10.1038/s41398-019-0426-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414668PMC
March 2019

Reduction in non-abstinent WHO drinking risk levels and depression/anxiety disorders: 3-year follow-up results in the US general population.

Drug Alcohol Depend 2019 04 14;197:228-235. Epub 2019 Feb 14.

Columbia University Mailman School of Public Health, 722 West 168th Street, New York, NY 10032, USA; New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440807PMC
April 2019

Reduction in non-abstinent WHO drinking risk levels and depression/anxiety disorders: 3-year follow-up results in the US general population.

Drug Alcohol Depend 2019 04 14;197:228-235. Epub 2019 Feb 14.

Columbia University Mailman School of Public Health, 722 West 168th Street, New York, NY 10032, USA; New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drugalcdep.2019.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440807PMC
April 2019

Longitudinal Drinking Patterns and Their Clinical Correlates in Million Veteran Program Participants.

Alcohol Clin Exp Res 2019 03 3;43(3):465-472. Epub 2019 Feb 3.

VA Connecticut Healthcare System , West Haven, Connecticut.

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http://dx.doi.org/10.1111/acer.13951DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691890PMC
March 2019

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Authors:
Raymond K Walters Renato Polimanti Emma C Johnson Jeanette N McClintick Mark J Adams Amy E Adkins Fazil Aliev Silviu-Alin Bacanu Anthony Batzler Sarah Bertelsen Joanna M Biernacka Tim B Bigdeli Li-Shiun Chen Toni-Kim Clarke Yi-Ling Chou Franziska Degenhardt Anna R Docherty Alexis C Edwards Pierre Fontanillas Jerome C Foo Louis Fox Josef Frank Ina Giegling Scott Gordon Laura M Hack Annette M Hartmann Sarah M Hartz Stefanie Heilmann-Heimbach Stefan Herms Colin Hodgkinson Per Hoffmann Jouke Jan Hottenga Martin A Kennedy Mervi Alanne-Kinnunen Bettina Konte Jari Lahti Marius Lahti-Pulkkinen Dongbing Lai Lannie Ligthart Anu Loukola Brion S Maher Hamdi Mbarek Andrew M McIntosh Matthew B McQueen Jacquelyn L Meyers Yuri Milaneschi Teemu Palviainen John F Pearson Roseann E Peterson Samuli Ripatti Euijung Ryu Nancy L Saccone Jessica E Salvatore Sandra Sanchez-Roige Melanie Schwandt Richard Sherva Fabian Streit Jana Strohmaier Nathaniel Thomas Jen-Chyong Wang Bradley T Webb Robbee Wedow Leah Wetherill Amanda G Wills Jason D Boardman Danfeng Chen Doo-Sup Choi William E Copeland Robert C Culverhouse Norbert Dahmen Louisa Degenhardt Benjamin W Domingue Sarah L Elson Mark A Frye Wolfgang Gäbel Caroline Hayward Marcus Ising Margaret Keyes Falk Kiefer John Kramer Samuel Kuperman Susanne Lucae Michael T Lynskey Wolfgang Maier Karl Mann Satu Männistö Bertram Müller-Myhsok Alison D Murray John I Nurnberger Aarno Palotie Ulrich Preuss Katri Räikkönen Maureen D Reynolds Monika Ridinger Norbert Scherbaum Marc A Schuckit Michael Soyka Jens Treutlein Stephanie Witt Norbert Wodarz Peter Zill Daniel E Adkins Joseph M Boden Dorret I Boomsma Laura J Bierut Sandra A Brown Kathleen K Bucholz Sven Cichon E Jane Costello Harriet de Wit Nancy Diazgranados Danielle M Dick Johan G Eriksson Lindsay A Farrer Tatiana M Foroud Nathan A Gillespie Alison M Goate David Goldman Richard A Grucza Dana B Hancock Kathleen Mullan Harris Andrew C Heath Victor Hesselbrock John K Hewitt Christian J Hopfer John Horwood William Iacono Eric O Johnson Jaakko A Kaprio Victor M Karpyak Kenneth S Kendler Henry R Kranzler Kenneth Krauter Paul Lichtenstein Penelope A Lind Matt McGue James MacKillop Pamela A F Madden Hermine H Maes Patrik Magnusson Nicholas G Martin Sarah E Medland Grant W Montgomery Elliot C Nelson Markus M Nöthen Abraham A Palmer Nancy L Pedersen Brenda W J H Penninx Bernice Porjesz John P Rice Marcella Rietschel Brien P Riley Richard Rose Dan Rujescu Pei-Hong Shen Judy Silberg Michael C Stallings Ralph E Tarter Michael M Vanyukov Scott Vrieze Tamara L Wall John B Whitfield Hongyu Zhao Benjamin M Neale Joel Gelernter Howard J Edenberg Arpana Agrawal

Nat Neurosci 2018 12 26;21(12):1656-1669. Epub 2018 Nov 26.

Washington University School of Medicine, Department of Psychiatry, St. Louis, MO, USA.

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http://dx.doi.org/10.1038/s41593-018-0275-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6430207PMC
December 2018

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.

Nat Genet 2019 01 26;51(1):63-75. Epub 2018 Nov 26.

Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://www.nature.com/articles/s41588-018-0269-7
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http://dx.doi.org/10.1038/s41588-018-0269-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481311PMC
January 2019

Predictors of Treatment Referral after AUDIT-C Screening for Heavy Drinking.

Addict Disord Their Treat 2018 Sep;17(3):124-133

Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://Insights.ovid.com/crossref?an=00132576-201809000-0000
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http://dx.doi.org/10.1097/ADT.0000000000000134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6159906PMC
September 2018

Risk Locus Identification Ties Alcohol Withdrawal Symptoms to SORCS2.

Alcohol Clin Exp Res 2018 12 25;42(12):2337-2348. Epub 2018 Oct 25.

Department of Psychiatry , Division of Human Genetics, VA CT Healthcare Center, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1111/acer.13890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317871PMC
December 2018

Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review.

JAMA 2018 08;320(8):815-824

Department of Psychiatry, Ludwig-Maximilians-University, Munich, Germany.

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http://dx.doi.org/10.1001/jama.2018.11406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7391072PMC
August 2018

Genome-wide association study of cognitive flexibility assessed by the Wisconsin Card Sorting Test.

Am J Med Genet B Neuropsychiatr Genet 2018 07;177(5):511-519

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1002/ajmg.b.32642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110090PMC
July 2018

Topiramate versus naltrexone for alcohol use disorder: study protocol for a genotype-stratified, double-blind randomised controlled trial (TOP study).

Trials 2018 Aug 16;19(1):443. Epub 2018 Aug 16.

University of Sydney, Faculty of Medicine and Health, Central Clinical School, NHMRC Centre of Research Excellence in Mental Health and Substance Use, Sydney, NSW, Australia.

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https://trialsjournal.biomedcentral.com/articles/10.1186/s13
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http://dx.doi.org/10.1186/s13063-018-2824-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097336PMC
August 2018

Genome-wide association meta-analysis of age at first cannabis use.

Addiction 2018 11 19;113(11):2073-2086. Epub 2018 Aug 19.

Department of Psychiatry, Academic Medical Centre, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1111/add.14368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087375PMC
November 2018

Opioid Misuse as a Predictor of Alcohol Treatment Outcomes in the COMBINE Study: Mediation by Medication Adherence.

Alcohol Clin Exp Res 2018 07 9;42(7):1249-1259. Epub 2018 Jun 9.

Center for Studies of Addiction, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/acer.13772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063524PMC
July 2018

Meta-Analysis of the Association of Alcohol-Related Social Media Use with Alcohol Consumption and Alcohol-Related Problems in Adolescents and Young Adults.

Alcohol Clin Exp Res 2018 06 22;42(6):978-986. Epub 2018 May 22.

Department of Psychiatry , Perelman School of Medicine, Center for Studies of Addiction, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://doi.wiley.com/10.1111/acer.13642
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http://dx.doi.org/10.1111/acer.13642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984178PMC
June 2018

Collaborative Phenotype Inference from Comorbid Substance Use Disorders and Genotypes.

Proceedings (IEEE Int Conf Bioinformatics Biomed) 2017 Nov 18;2017:392-397. Epub 2017 Dec 18.

Department of Computer Science and Engineering, University of Connecticut, Storrs, Connecticut.

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http://dx.doi.org/10.1109/BIBM.2017.8217681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5947969PMC
November 2017

Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.

Biol Psychiatry 2018 11 11;84(10):762-770. Epub 2018 Jan 11.

Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, Massachusetts; Departments of Genetics and Neuroscience, Yale University School of Medicine, New Haven, Massachusetts; VA Connecticut Healthcare Center, West Haven, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2017.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041180PMC
November 2018

Examining the effects of alcohol on GABA receptor mRNA expression and function in neural cultures generated from control and alcohol dependent donor induced pluripotent stem cells.

Alcohol 2018 02 12;66:45-53. Epub 2017 Aug 12.

Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington, CT, 06030-1410, USA; Institute for Systems Genomics, University of Connecticut, Storrs, CT, 06268, USA. Electronic address:

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http://dx.doi.org/10.1016/j.alcohol.2017.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743620PMC
February 2018

Effects of Recent Alcohol Consumption Level on Neurocognitive Performance in HIV+ Individuals.

Addict Disord Their Treat 2017 Sep;16(3):95-107

Behavioral Health Service, Crescenz VAMC, 3900 Woodland Ave., Philadelphia, PA 19104.

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http://dx.doi.org/10.1097/ADT.0000000000000109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654614PMC
September 2017

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

JAMA Psychiatry 2017 12;74(12):1234-1241

Division of Human Genetics, Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1001/jamapsychiatry.2017.3275DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331050PMC
December 2017

Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors.

Am J Med Genet B Neuropsychiatr Genet 2017 Dec 9;174(8):846-853. Epub 2017 Oct 9.

Department of Psychiatry, Yale University School of Medicine, West Haven, Connecticut.

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http://dx.doi.org/10.1002/ajmg.b.32604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861711PMC
December 2017

Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study.

J Psychiatr Res 2017 11 8;94:139-147. Epub 2017 Jul 8.

U.S. Department of Veterans Affairs National Center for Posttraumatic Stress Disorder, Clinical Neurosciences Division, VA Connecticut Healthcare System, West Haven, CT, USA; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1016/j.jpsychires.2017.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605420PMC
November 2017

Precision medicine and pharmacogenetics: what does oncology have that addiction medicine does not?

Addiction 2017 Dec 21;112(12):2086-2094. Epub 2017 Apr 21.

Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/add.13818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650957PMC
December 2017

identified in a genome-wide gene × cannabis dependence interaction analysis of risky sexual behaviours.

J Psychiatry Neurosci 2017 06;42(4):252-261

From the Department of Psychiatry, Yale University School of Medicine and VA CT Healthcare Center, West Haven, Conn., USA (Polimanti, Pearlson, Gelernter); Olin Research Center, Institute of Living/Hartford Hospital, Hartford, Conn., USA (Meda, Pearlson); the Department of Neuroscience, Yale University School of Medicine, New Haven, Conn., USA (Pearlson, Gelernter); the Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, Mass., USA (Sherva, Farrer); the Department of Biostatistics, Yale University School of Public Health, New Haven, Conn., USA (Zhao); the Department of Genetics, Yale University School of Medicine, New Haven, Conn., USA (Zhao, Gelernter); the Departments of Neurology, Ophthalmology, Biostatistics, and Epidemiology, Boston University Schools of Medicine and Public Health, Boston, Mass., USA (Farrer); and the Department of Psychiatry, University of Pennsylvania School of Medicine and VISN 4 MIRECC, Crescenz VAMC, Philadelphia, Pa., USA (Kranzler).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5487272PMC
http://dx.doi.org/10.1503/jpn.160189DOI Listing
June 2017

Correlates of Electronic Cigarettes Use Before and During Pregnancy.

Nicotine Tob Res 2017 May;19(5):585-590

Department of Obstetrics and Gynecology, Baystate Medical Center, Springfield, MA.

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http://dx.doi.org/10.1093/ntr/ntw225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896457PMC
May 2017

Validating Harmful Alcohol Use as a Phenotype for Genetic Discovery Using Phosphatidylethanol and a Polymorphism in ADH1B.

Alcohol Clin Exp Res 2017 May 10;41(5):998-1003. Epub 2017 Apr 10.

Department of Psychiatry, University of Pennsylvania Perelman School of Medicine and VISN 4 MIRECC, Crescenz VAMC, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1111/acer.13373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501250PMC
May 2017

Temporal Stability of Heavy Drinking Days and Drinking Reductions Among Heavy Drinkers in the COMBINE Study.

Alcohol Clin Exp Res 2017 May 5;41(5):1054-1062. Epub 2017 Apr 5.

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina.

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http://dx.doi.org/10.1111/acer.13371DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5404970PMC
May 2017

Alcohol and nicotine codependence-associated DNA methylation changes in promoter regions of addiction-related genes.

Sci Rep 2017 02 6;7:41816. Epub 2017 Feb 6.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1038/srep41816DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292964PMC
February 2017

Effects of LY466195, a selective kainate receptor antagonist, on ethanol preference and drinking in rats.

Neurosci Lett 2017 02 21;639:8-12. Epub 2016 Dec 21.

Center for Neurobiology and Behavior, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, United States; Department of Biobehavioral Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, PA 19104, United States. Electronic address:

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http://dx.doi.org/10.1016/j.neulet.2016.12.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5272788PMC
February 2017

Guidelines for biological treatment of substance use and related disorders, part 1: Alcoholism, first revision.

World J Biol Psychiatry 2017 03 23;18(2):86-119. Epub 2016 Dec 23.

b Department of Psychiatry , Ludwig-Maximilians-University , Munich , Germany.

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http://dx.doi.org/10.1080/15622975.2016.1246752DOI Listing
March 2017

Examining FKBP5 mRNA expression in human iPSC-derived neural cells.

Psychiatry Res 2017 Jan 24;247:172-181. Epub 2016 Nov 24.

Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington 06030-1410, CT, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01651781163116
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http://dx.doi.org/10.1016/j.psychres.2016.11.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5191911PMC
January 2017

Urgency traits moderate daily relations between affect and drinking to intoxication among young adults.

Drug Alcohol Depend 2017 Jan 3;170:59-65. Epub 2016 Nov 3.

Yale School of Medicine, Department of Psychiatry, New Haven, CT, United States; Yale Cancer Center, New Haven, CT, United States.

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http://dx.doi.org/10.1016/j.drugalcdep.2016.10.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183550PMC
January 2017

Sex-specific linkage scans in opioid dependence.

Am J Med Genet B Neuropsychiatr Genet 2017 Apr 20;174(3):261-268. Epub 2016 Oct 20.

Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1002/ajmg.b.32507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695218PMC
April 2017

The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene.

Neuropsychopharmacology 2017 02 17;42(3):598-605. Epub 2016 Aug 17.

Department of Psychiatry, Yale University School of Medicine and VA CT Healthcare Center, West Haven, CT, USA.

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http://dx.doi.org/10.1038/npp.2016.153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5240175PMC
February 2017

Reductions in Alcohol Craving Following Naltrexone Treatment for Heavy Drinking.

Alcohol Alcohol 2016 Sep 11;51(5):562-6. Epub 2016 Jul 11.

VISN 4 MIRECC, Corporal Michael Crescenz VAMC Center for Studies of Addiction, University of Pennsylvania Perelman School of Medicine.

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http://dx.doi.org/10.1093/alcalc/agw038DOI Listing
September 2016

Missing Data in Alcohol Clinical Trials with Binary Outcomes.

Alcohol Clin Exp Res 2016 07 2;40(7):1548-57. Epub 2016 Jun 2.

Department of Psychiatry, Addiction Sciences Division, Medical University of South Carolina, Charleston, South Carolina.

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http://dx.doi.org/10.1111/acer.13106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5522809PMC
July 2016

FKBP5 genotype interacts with early life trauma to predict heavy drinking in college students.

Am J Med Genet B Neuropsychiatr Genet 2016 09 19;171(6):879-87. Epub 2016 May 19.

Alcohol Research Center, Department of Psychiatry, University of Connecticut School of Medicine, Farmington, Connecticut.

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http://doi.wiley.com/10.1002/ajmg.b.32460
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5045724PMC
http://dx.doi.org/10.1002/ajmg.b.32460DOI Listing
September 2016

Phenome-Wide Association Study for Alcohol and Nicotine Risk Alleles in 26394 Women.

Neuropsychopharmacology 2016 10 17;41(11):2688-96. Epub 2016 May 17.

Department of Psychiatry, Yale School of Medicine, West Haven, CT, USA.

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http://www.nature.com/articles/npp201672
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http://dx.doi.org/10.1038/npp.2016.72DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026736PMC
October 2016

New Initiatives for Alcoholism: Clinical and Experimental Research.

Authors:
Henry R Kranzler

Alcohol Clin Exp Res 2016 Apr 24;40(4):652. Epub 2016 Feb 24.

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http://dx.doi.org/10.1111/acer.13018DOI Listing
April 2016

Balancing risk and benefit in heavy drinkers treated with topiramate: implications for personalized care.

J Clin Psychiatry 2016 Mar;77(3):e278-82

Department of Medical Sciences, Frank Netter School of Medicine, Quinnipiac University, Hamden, Connecticut.

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http://dx.doi.org/10.4088/JCP.15m10053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845738PMC
March 2016

Smoking and Cellular Telephone Use Among Pregnant Women Seeking Prenatal Care: Opportunities for Intervention.

Addict Disord Their Treat 2015 Dec 29;14(4):203-210. Epub 2014 May 29.

Treatment Research Center, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104; Philadelphia VAMC, Philadelphia, PA 19104.

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http://dx.doi.org/10.1097/ADT.0000000000000053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705558PMC
December 2015