Henry J Pownall

Henry J Pownall

UNVERIFIED PROFILE

Are you Henry J Pownall?   Register this Author

Register author
Henry J Pownall

Henry J Pownall

Publications by authors named "Henry J Pownall"

Are you Henry J Pownall?   Register this Author

91Publications

965Reads

43Profile Views

Lipids and Cardiovascular Disease: Putting It All Together.

Methodist Debakey Cardiovasc J 2019 Jan-Mar;15(1):5-8

HOUSTON METHODIST RESEARCH INSTITUTE, HOUSTON, TEXAS; WEILL CORNELL MEDICINE, NEW YORK, NEW YORK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14797/mdcj-15-1-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489600PMC
June 2019

Cholesterol: Can't Live With It, Can't Live Without It.

Methodist Debakey Cardiovasc J 2019 Jan-Mar;15(1):9-15

HOUSTON METHODIST RESEARCH INSTITUTE, HOUSTON, TEXAS; WEILL CORNELL MEDICINE, NEW YORK, NEW YORK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14797/mdcj-15-1-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489611PMC
June 2019

Revisiting Reverse Cholesterol Transport in the Context of High-Density Lipoprotein Free Cholesterol Bioavailability.

Methodist Debakey Cardiovasc J 2019 Jan-Mar;15(1):47-54

HOUSTON METHODIST RESEARCH INSTITUTE, HOUSTON METHODIST HOSPITAL, HOUSTON, TEXAS.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14797/mdcj-15-1-47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6489609PMC
June 2019

Somatic Editing of Ldlr With Adeno-Associated Viral-CRISPR Is an Efficient Tool for Atherosclerosis Research.

Arterioscler Thromb Vasc Biol 2018 09;38(9):1997-2006

From the Department of Molecular Physiology and Biophysics (K.E.J., M.D.G., A.H., A.M.D., W.R.L.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.118.311221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6202188PMC
September 2018

Rethinking apolipoprotein A-II in lipid metabolism.

Authors:
Henry J Pownall

Am J Clin Nutr 2018 07;108(1):4-5

Center for Bioenergetics, Houston Methodist Research Institute, Houston, TX.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ajcn/nqy136DOI Listing
July 2018

Rethinking reverse cholesterol transport and dysfunctional high-density lipoproteins.

J Clin Lipidol 2018 Jul - Aug;12(4):849-856. Epub 2018 Apr 12.

Center for Bioenergetics, Houston Methodist Research Institute, Houston, TX, USA; Weill Cornell Medicine, New York, NY, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jacl.2018.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6064676PMC
April 2018

ABCA1-Derived Nascent High-Density Lipoprotein-Apolipoprotein AI and Lipids Metabolically Segregate.

Arterioscler Thromb Vasc Biol 2017 12 26;37(12):2260-2270. Epub 2017 Oct 26.

From the Center for Bioenergetics and Department of Medicine, Houston Methodist Research Institute, TX (B.X., B.K.G., A.M.G., C.R., H.J.P.); and Department of Cardiovascular Medicine, Xiangya Hospital, Central South University, Changsha, China (B.X.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.117.310290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831354PMC
December 2017

Structural Stability of Streptococcal Serum Opacity Factor.

Protein J 2017 06;36(3):196-201

The Center for Bioenergetics and Metabolism, Houston Methodist Research Institute, 6670 Bertner St., Houston, TX, 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10930-017-9711-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448415PMC
June 2017

AIBP Limits Angiogenesis Through γ-Secretase-Mediated Upregulation of Notch Signaling.

Circ Res 2017 May 21;120(11):1727-1739. Epub 2017 Mar 21.

From the Center for Cardiovascular Regeneration, Department of Cardiovascular Sciences (R.M., S.M., Q.G., R.A.-G., Q.Y., J.P.C., L.F.), Houston Methodist DeBakey Heart and Vascular Center, Department of Cardiology (R.A.-G., K.A.Y.), Department of Bioenergetics (H.J.P.), Houston Methodist Research Institute, TX; Department of Ophthalmology, Baylor College of Medicine, Houston, TX (S.K., Y.F.); and Department of Medicine, University of California, San Diego, La Jolla (F.A., Y.I.M.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/CIRCRESAHA.116.309754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446274PMC
May 2017

Acylation of lysine residues in human plasma high density lipoprotein increases stability and plasma clearance in vivo.

Biochim Biophys Acta 2016 11 2;1861(11):1787-1795. Epub 2016 Sep 2.

Houston Methodist Research Institute, 6670 Bertner Avenue, Houston, TX 77030, USA; Weill Cornell Medicine, 1305 York Avenue, New York, NY 10065, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2016.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5129619PMC
November 2016

Neo High-Density Lipoprotein Produced by the Streptococcal Serum Opacity Factor Activity against Human High-Density Lipoproteins Is Hepatically Removed via Dual Mechanisms.

Biochemistry 2016 10 7;55(41):5845-5853. Epub 2016 Oct 7.

Houston Methodist Research Institute , 6670 Bertner Avenue, Houston, Texas 77030, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.biochem.6b00946DOI Listing
October 2016

High-Density Lipoprotein Processing and Premature Cardiovascular Disease.

Methodist Debakey Cardiovasc J 2015 Jul-Sep;11(3):181-5

Houston Methodist Research Institute, Houston Methodist Hospital, Houston, Texas ; Weill Cornell Medical College, New York, New York.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14797/mdcj-11-3-181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666426PMC
September 2016

Streptococcal serum opacity factor promotes cholesterol ester metabolism and bile acid secretion in vitro and in vivo.

Biochim Biophys Acta 2016 Mar 18;1861(3):196-204. Epub 2015 Dec 18.

The Laboratory of Atherosclerosis and Lipoprotein Research, Houston Methodist Research Institute, 6670 Bertner St., Houston, TX 77030, USA; Department of Medicine, Weill Cornell Medical College, 1305 York Ave., New York, NY 10021, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2015.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4804621PMC
March 2016

E-selectin-targeting delivery of microRNAs by microparticles ameliorates endothelial inflammation and atherosclerosis.

Sci Rep 2016 Mar 9;6:22910. Epub 2016 Mar 9.

Department of Cardiovascular Sciences, Houston Methodist Research Institute, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep22910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783714PMC
March 2016

Direct Measurement of the Structure of Reconstituted High-Density Lipoproteins by Cryo-EM.

Biophys J 2016 Feb 30;110(4):810-6. Epub 2015 Dec 30.

Houston Methodist Research Institute, Houston, Texas; Weill Cornell Medicine, Houston, Texas. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bpj.2015.10.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775836PMC
February 2016

New Insights into the High-Density Lipoprotein Dilemma.

Trends Endocrinol Metab 2016 Jan 7;27(1):44-53. Epub 2015 Dec 7.

Weill-Cornell Medicine, 1305 York Avenue, New York, NY, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tem.2015.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707953PMC
January 2016

Estrogen: an emerging regulator of insulin action and mitochondrial function.

J Diabetes Res 2015 26;2015:916585. Epub 2015 Mar 26.

Bioenergetics Laboratory, Houston Methodist Research Institute, Weill Cornell Medical College, 6565 Fannin Street, Houston, TX 77030, USA ; Houston Methodist Department of Medicine, Weill Cornell Medical College, 6550 Fannin, Suite 1001, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://downloads.hindawi.com/journals/jdr/2015/916585.pdf
Web Search
http://www.hindawi.com/journals/jdr/2015/916585/
Publisher Site
http://dx.doi.org/10.1155/2015/916585DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391691PMC
December 2015

Apolipoprotein AI deficiency inhibits serum opacity factor activity against plasma high density lipoprotein via a stabilization mechanism.

Biochemistry 2015 Apr 2;54(14):2295-302. Epub 2015 Apr 2.

†Laboratory of Atherosclerosis and Lipoprotein Research, Department of Cardiology, Houston Methodist Research Institute, 6670 Bertner Avenue, Houston, Texas 77030, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi501486zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893950PMC
April 2015

Changes in body composition over 8 years in a randomized trial of a lifestyle intervention: the look AHEAD study.

Obesity (Silver Spring) 2015 Mar;23(3):565-72

Department of Cardiology, Division of Atherosclerosis, Houston Methodist Research Institute and Baylor College of Medicine, Houston, Texas, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/oby.21005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4707962PMC
March 2015

Alcohol: a nutrient with multiple salutary effects.

Nutrients 2015 Mar 18;7(3):1992-2000. Epub 2015 Mar 18.

Department of Cardiology, Division of Atherosclerosis, Houston Methodist Research Institute, Fondren F8-047, 6670 Bertner St., Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/nu7031992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4377895PMC
March 2015

Modest diet-induced weight loss reduces macrophage cholesterol efflux to plasma of patients with metabolic syndrome.

J Clin Lipidol 2013 Nov-Dec;7(6):661-70. Epub 2013 May 25.

Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S19332874130020
Publisher Site
http://dx.doi.org/10.1016/j.jacl.2013.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108339PMC
July 2014

Setting the course for apoAII: a port in sight?

Clin Lipidol 2013 Oct;8(5):551-560

Houston Methodist Research Institute, 6670 Bertner Avenue, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/clp.13.59DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108335PMC
October 2013

Impaired lipoprotein processing in HIV patients on antiretroviral therapy: aberrant high-density lipoprotein lipids, stability, and function.

Arterioscler Thromb Vasc Biol 2013 Jul 2;33(7):1714-21. Epub 2013 May 2.

Section of Atherosclerosis and Vascular Medicine, Baylor College of Medicine, Houston, TX, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.113.301538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4232239PMC
July 2013

Intensive lifestyle modification reduces Lp-PLA2 in dyslipidemic HIV/HAART patients.

Med Sci Sports Exerc 2013 Jun;45(6):1043-50

Division of Atherosclerosis and Vascular Biology, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1249/MSS.0b013e3182843961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655089PMC
June 2013

Free cholesterol determines reassembled high-density lipoprotein phospholipid phase structure and stability.

Biochemistry 2013 Jun 14;52(25):4324-30. Epub 2013 Jun 14.

Cardiovascular and Thrombosis Research Section, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi4006732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959168PMC
June 2013

Cholesterol determines and limits rHDL formation from human plasma apolipoprotein A-II and phospholipid membranes.

Biochemistry 2012 Oct 16;51(43):8627-35. Epub 2012 Oct 16.

Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi3011994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483724PMC
October 2012

ApoE and the role of very low density lipoproteins in adipose tissue inflammation.

Atherosclerosis 2012 Aug 19;223(2):342-9. Epub 2012 Jun 19.

Division of Atherosclerosis and Vascular Medicine, Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, 6565 Fannin, M.S. A-601, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2012.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411924PMC
August 2012

The structure and function of serum opacity factor: a unique streptococcal virulence determinant that targets high-density lipoproteins.

J Biomed Biotechnol 2010 8;2010:956071. Epub 2010 Jul 8.

Veterans Affairs Medical Center and Department of Medicine, University of Tennessee Health Science Center, 1030 Jefferson Avenue, Memphis, TN 38104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1155/2010/956071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910554PMC
January 2011

Serum opacity factor enhances HDL-mediated cholesterol efflux, esterification and anti inflammatory effects.

Lipids 2010 Dec 24;45(12):1117-26. Epub 2010 Oct 24.

Department of Medicine, Baylor College of Medicine, MSA601, One Baylor Plaza, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11745-010-3484-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3036000PMC
December 2010

Speciated human high-density lipoprotein protein proximity profiles.

Biochemistry 2010 Dec 23;49(50):10656-65. Epub 2010 Nov 23.

Department of Pathology and Laboratory Medicine, University of Cincinnati, Cincinnati, Ohio 45237, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi1015452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3006032PMC
December 2010

Streptococcal serum opacity factor increases the rate of hepatocyte uptake of human plasma high-density lipoprotein cholesterol.

Biochemistry 2010 Nov 25;49(45):9866-73. Epub 2010 Oct 25.

Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi101412mDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2982792PMC
November 2010

JNK deficiency enhances fatty acid utilization and diverts glucose from oxidation to glycogen storage in cultured myotubes.

Obesity (Silver Spring) 2010 Sep 21;18(9):1701-9. Epub 2010 Jan 21.

Department of Physiology and Biophysics, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/oby.2009.501DOI Listing
September 2010

HDL superphospholipidation enhances key steps in reverse cholesterol transport.

Atherosclerosis 2010 Apr 12;209(2):430-5. Epub 2009 Oct 12.

Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, MS A-601, 6565 Fannin Street, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2009.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846204PMC
April 2010

Mechanism of LDL binding and release probed by structure-based mutagenesis of the LDL receptor.

J Lipid Res 2010 Feb 11;51(2):297-308. Epub 2009 Aug 11.

Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M000422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803231PMC
February 2010

Model of human low-density lipoprotein and bound receptor based on cryoEM.

Proc Natl Acad Sci U S A 2010 Jan 28;107(3):1059-64. Epub 2009 Dec 28.

Department of Biochemistry & Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.0908004107
Publisher Site
http://dx.doi.org/10.1073/pnas.0908004107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798884PMC
January 2010

Apolipoproteins A-I, A-II and E are independently distributed among intracellular and newly secreted HDL of human hepatoma cells.

Biochim Biophys Acta 2009 Dec 25;1791(12):1125-32. Epub 2009 Jul 25.

Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, MS-A601, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2009.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2783830PMC
December 2009

Apolipoprotein modulation of streptococcal serum opacity factor activity against human plasma high-density lipoproteins.

Biochemistry 2009 Aug;48(33):8070-6

Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi901087zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3236702PMC
August 2009

Mass spectrometric determination of apolipoprotein molecular stoichiometry in reconstituted high density lipoprotein particles.

J Lipid Res 2009 Jun 28;50(6):1229-36. Epub 2009 Jan 28.

Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.D800044-JLR200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2681406PMC
June 2009

The adipocyte IKK/NFkappaB pathway: a therapeutic target for insulin resistance.

Curr Opin Investig Drugs 2009 Apr;10(4):346-52

University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, Department of Physiology and Biophysics, 683 Hoes Lane West, Piscataway, NJ 08854, USA.

View Article

Download full-text PDF

Source
April 2009

Disruption of human plasma high-density lipoproteins by streptococcal serum opacity factor requires labile apolipoprotein A-I.

Biochemistry 2009 Feb;48(7):1481-7

Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi802287qDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2962917PMC
February 2009

Properties of the products formed by the activity of serum opacity factor against human plasma high-density lipoproteins.

Chem Phys Lipids 2008 Nov 16;156(1-2):45-51. Epub 2008 Sep 16.

Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, MS A601, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chemphyslip.2008.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891100PMC
November 2008

Cholesterol is a determinant of the structures of discoidal high density lipoproteins formed by the solubilization of phospholipid membranes by apolipoprotein A-I.

Biochim Biophys Acta 2008 May 21;1781(5):245-53. Epub 2008 Mar 21.

Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbalip.2008.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447930PMC
May 2008

Shear-induced disulfide bond formation regulates adhesion activity of von Willebrand factor.

J Biol Chem 2007 Dec 9;282(49):35604-11. Epub 2007 Oct 9.

Section of Thrombosis Research, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M704047200DOI Listing
December 2007

Serum opacity factor unmasks human plasma high-density lipoprotein instability via selective delipidation and apolipoprotein A-I desorption.

Biochemistry 2007 Nov 17;46(45):12968-78. Epub 2007 Oct 17.

Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi701525wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2884138PMC
November 2007

Brain uptake and utilization of fatty acids, lipids & lipoproteins: recommendations for future research.

J Mol Neurosci 2007 Sep;33(1):146-50

Omega-3 Research Institute, Inc., 16700 Sioux Lane, Gaithersburg, MD 20878, USA.

View Article

Download full-text PDF

Source
September 2007

Pro-apoptotic low-density lipoprotein subfractions in type II diabetes.

Atherosclerosis 2007 Aug 9;193(2):283-91. Epub 2006 Oct 9.

Department of Medicine, Baylor College of Medicine, 6565 Fannin, MS A.601, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2006.08.059DOI Listing
August 2007

Interaction effects of high-density lipoprotein metabolism gene variation and alcohol consumption on coronary heart disease risk: the atherosclerosis risk in communities study.

J Stud Alcohol Drugs 2007 Jul;68(4):485-92

University of Texas Health Science Center, School of Public Health, Human Genetics Center, 1200 Hermann Pressler, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2731423PMC
http://dx.doi.org/10.15288/jsad.2007.68.485DOI Listing
July 2007

Speciation of human plasma high-density lipoprotein (HDL): HDL stability and apolipoprotein A-I partitioning.

Biochemistry 2007 Jun 27;46(25):7449-59. Epub 2007 May 27.

Section of Atherosclerosis and Vascular Medicine, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi700496wDOI Listing
June 2007

Sustained elevations in NEFA induce cyclooxygenase-2 activity and potentiate THP-1 macrophage foam cell formation.

Atherosclerosis 2007 May 25;192(1):49-55. Epub 2006 Jul 25.

Section of Atherosclerosis and Lipoprotein Research, Department of Medicine, MS A-601, Baylor College of Medicine, 6565 Fannin St., Houston, TX 77030, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2006.06.014DOI Listing
May 2007

Dynamics of dense electronegative low density lipoproteins and their preferential association with lipoprotein phospholipase A(2).

J Lipid Res 2007 Feb 13;48(2):348-57. Epub 2006 Nov 13.

Section of Atherosclerosis and Lipoprotein Research, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M600249-JLR200DOI Listing
February 2007

Electronegative LDLs from familial hypercholesterolemic patients are physicochemically heterogeneous but uniformly proapoptotic.

J Lipid Res 2007 Jan 2;48(1):177-84. Epub 2006 Oct 2.

Section of Atherosclerosis and Lipoprotein Research, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1194/jlr.M500481-JLR200DOI Listing
January 2007

Heart positive: design of a randomized controlled clinical trial of intensive lifestyle intervention, niacin and fenofibrate for HIV lipodystrophy/dyslipidemia.

Contemp Clin Trials 2006 Dec 21;27(6):518-30. Epub 2006 Jul 21.

Translational Metabolism Unit, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX 77030, United States.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S155171440600092
Publisher Site
http://dx.doi.org/10.1016/j.cct.2006.07.002DOI Listing
December 2006

Structures of biologically active oxysterols determine their differential effects on phospholipid membranes.

Biochemistry 2006 Sep;45(35):10747-58

Section of Atherosclerosis and Lipoprotein Research, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi060540uDOI Listing
September 2006

Detergent-mediated phospholipidation of plasma lipoproteins increases HDL cholesterophilicity and cholesterol efflux via SR-BI.

Authors:
Henry J Pownall

Biochemistry 2006 Sep;45(38):11514-22

Section of Atherosclerosis and Lipoprotein Research, Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi0608717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2556864PMC
September 2006

Modulation of angiogenic processes in cultured endothelial cells by low density lipoproteins subfractions from patients with familial hypercholesterolemia.

Atherosclerosis 2006 Jun 26;186(2):448-57. Epub 2005 Sep 26.

Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.atherosclerosis.2005.08.022DOI Listing
June 2006

N-Glycosylation is required for secretion-competent human plasma phospholipid transfer protein.

Protein J 2006 Feb;25(2):167-73

MS A-601, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10930-006-0008-2DOI Listing
February 2006

Role of oxysterol structure on the microdomain-induced microsolubilization of phospholipid membranes by apolipoprotein A-I.

Biochemistry 2005 Nov;44(43):14376-84

Section of Atherosclerosis and Lipoprotein Research, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi051169yDOI Listing
November 2005

The polar nature of 7-ketocholesterol determines its location within membrane domains and the kinetics of membrane microsolubilization by apolipoprotein A-I.

Biochemistry 2005 Aug;44(30):10423-33

Section of Atherosclerosis and Lipoprotein Research, Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi0506425DOI Listing
August 2005

Remodeling of human plasma lipoproteins by detergent perturbation.

Authors:
Henry J Pownall

Biochemistry 2005 Jul;44(28):9714-22

Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/bi050729q
Publisher Site
http://dx.doi.org/10.1021/bi050729qDOI Listing
July 2005

Enhancing reverse cholesterol transport: the case for phosphatidylcholine therapy.

Curr Opin Lipidol 2005 Jun;16(3):265-8

View Article

Download full-text PDF

Source
June 2005

Severely dysregulated disposal of postprandial triacylglycerols exacerbates hypertriacylglycerolemia in HIV lipodystrophy syndrome.

Am J Clin Nutr 2005 Jun;81(6):1405-10

Translation Metabolism Unit, Division of Diabetes, Endocrinology and Metabolism, Baylor College of Medicine, Houston, TX 77030-2600, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ajcn/81.6.1405DOI Listing
June 2005

Plasma factors required for human apolipoprotein A-II dimerization.

Biochemistry 2005 Jan;44(2):471-9

Department of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi048591jDOI Listing
January 2005

Cardiovascular implications of HIV-associated dyslipidemic lipodystrophy.

Curr Atheroscler Rep 2004 May;6(3):173-9

Division of Endocrinology, Baylor College of Medicine, 719E, One Baylor Plaza, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
May 2004

Pathophysiology of dyslipidemia and increased cardiovascular risk in HIV lipodystrophy: a model of 'systemic steatosis'.

Curr Opin Lipidol 2004 Feb;15(1):59-67

Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
February 2004

Structure of triglyceride-rich human low-density lipoproteins according to cryoelectron microscopy.

Biochemistry 2003 Dec;42(50):14988-93

Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi0354738DOI Listing
December 2003

Troglitazone antagonizes tumor necrosis factor-alpha-induced reprogramming of adipocyte gene expression by inhibiting the transcriptional regulatory functions of NF-kappaB.

J Biol Chem 2003 Jul 5;278(30):28181-92. Epub 2003 May 5.

Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M303141200
Publisher Site
http://dx.doi.org/10.1074/jbc.M303141200DOI Listing
July 2003

Isolation, characterization, and functional assessment of oxidatively modified subfractions of circulating low-density lipoproteins.

Arterioscler Thromb Vasc Biol 2003 Jun 10;23(6):1083-90. Epub 2003 Apr 10.

Department of Medicine, Baylor College of Medicine, 6565 Fannin, MS A.601, Houston, Tex 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.ATV.0000071350.78872.C4DOI Listing
June 2003

Structural and functional determinants of human plasma phospholipid transfer protein activity as revealed by site-directed mutagenesis of charged amino acids.

Biochemistry 2003 Apr;42(15):4444-51

Department of Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/bi027006gDOI Listing
April 2003

Metabolic basis of HIV-lipodystrophy syndrome.

Am J Physiol Endocrinol Metab 2002 Aug;283(2):E332-7

Section of Endocrinology and Department of Medicine, Children's Nutrition Research Center and US Department of Agriculture/Agricultural Research Service, Baylor College of Medicine, Houston 77030, USA.

View Article

Download full-text PDF

Source
http://www.physiology.org/doi/10.1152/ajpendo.00058.2002
Publisher Site
http://dx.doi.org/10.1152/ajpendo.00058.2002DOI Listing
August 2002

Alcohol: lipid metabolism and cardioprotection.

Authors:
Henry J Pownall

Curr Atheroscler Rep 2002 Mar;4(2):107-12

Baylor College of Medicine, 6565 Fannin, MS A601, Houston, TX 77030, USA.

View Article

Download full-text PDF

Source
March 2002