Henry J Haringsma

Henry J Haringsma

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Henry J Haringsma

Henry J Haringsma

Publications by authors named "Henry J Haringsma"

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12Publications

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Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC.

Cancer Discov 2013 Dec 24;3(12):1404-15. Epub 2013 Sep 24.

1Clovis Oncology Inc., San Francisco, California; 2Celgene Avilomics Research, Bedford, Massachusetts; 3Division of Hematology-Oncology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee; 4Mouse Cancer Genetics Program; and 5Center for Advanced Preclinical Research, Science Applications International Corporation-Frederick, Inc., National Cancer Institute, Frederick, Maryland.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048995PMC
December 2013

Adenosine modification may be preferred for reducing siRNA immune stimulation.

Nucleic Acid Ther 2012 Jun 20;22(3):205-10. Epub 2012 Apr 20.

Sirna Therapeutics, a wholly owned subsidiary of Merck and Co., San Francisco, California, USA.

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http://dx.doi.org/10.1089/nat.2011.0334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4047996PMC
June 2012

mRNA knockdown by single strand RNA is improved by chemical modifications.

Nucleic Acids Res 2012 May 16;40(9):4125-36. Epub 2012 Jan 16.

Sirna Therapeutics, 1700 Owens Street, Fourth Floor, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1093/nar/gkr1301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3351186PMC
May 2012

In vivo activity and duration of short interfering RNAs containing a synthetic 5'-phosphate.

Nucleic Acid Ther 2012 Apr 8;22(2):90-5. Epub 2012 Mar 8.

Sirna Therapeutics, San Francisco, California, USA.

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http://dx.doi.org/10.1089/nat.2011.0333DOI Listing
April 2012

Nucleobase and ribose modifications control immunostimulation by a microRNA-122-mimetic RNA.

J Am Chem Soc 2011 Jun 1;133(24):9200-3. Epub 2011 Jun 1.

Department of Chemistry, University of California-Davis, One Shields Avenue, Davis, California 95616, USA.

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http://dx.doi.org/10.1021/ja202492eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3116021PMC
June 2011