Publications by authors named "Henry A Lester"

174Publications

Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning.

Cell 2020 Dec 16;183(7):1986-2002.e26. Epub 2020 Dec 16.

Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA. Electronic address:

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December 2020

Proteins for increased surface expression of the α6β4 nicotinic acetylcholine receptor: nothing but good news?

J Clin Invest 2020 Nov;130(11):5685-5687

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA.

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November 2020

Nicotine Bound to Its Receptors: New Structures for a Vexing Pathopharmacological Problem.

Neuron 2019 11;104(3):431-432

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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November 2019

Brain Region-Specific nAChR and Associated Protein Abundance Alterations Following Chronic Nicotine and/or Menthol Exposure.

J Proteome Res 2020 01 28;19(1):36-48. Epub 2019 Oct 28.

Division of Biology and Biological Engineering , California Institute of Technology , 1200 East California Boulevard , Pasadena , California 91125-2900 , United States.

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January 2020

Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor.

J Am Chem Soc 2019 10 24;141(40):15840-15849. Epub 2019 Sep 24.

School of Chemistry , University of Bristol , Bristol BS8 1TS , United Kingdom.

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October 2019

Chronic Menthol Does Not Change Stoichiometry or Functional Plasma Membrane Levels of Mouse 34-Containing Nicotinic Acetylcholine Receptors.

Mol Pharmacol 2019 04 22;95(4):398-407. Epub 2019 Jan 22.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California (S.B., C.H.K., H.A.L.); and Department of Biomedical Sciences, Joan C. Edwards School of Medicine at Marshall University, Huntington, West Virginia (B.J.H.)

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April 2019

Bidirectional dopamine modulation of excitatory and inhibitory synaptic inputs to subthalamic neuron subsets containing α4β2 or α7 nAChRs.

Neuropharmacology 2019 04 17;148:220-228. Epub 2019 Jan 17.

Division of Biology, California Institute of Technology, Pasadena, CA, 91125, USA. Electronic address:

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April 2019

α1-FANGs: Protein Ligands Selective for the α-Bungarotoxin Site of the α1-Nicotinic Acetylcholine Receptor.

ACS Chem Biol 2018 09 13;13(9):2568-2576. Epub 2018 Aug 13.

Department of Chemistry , University of Southern California , Los Angeles , California 90089-1062 , United States.

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September 2018

Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type α-synuclein.

Neurobiol Dis 2018 09 1;117:170-180. Epub 2018 Jun 1.

Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA. Electronic address:

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September 2018

Deletion of lynx1 reduces the function of α6* nicotinic receptors.

PLoS One 2017 5;12(12):e0188715. Epub 2017 Dec 5.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, United States of America.

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December 2017

Acute Ethanol Administration Upregulates Synaptic α4-Subunit of Neuronal Nicotinic Acetylcholine Receptors within the Nucleus Accumbens and Amygdala.

Front Mol Neurosci 2017 24;10:338. Epub 2017 Oct 24.

Translational Research Institute, Institute for Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.

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October 2017

TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors.

Front Pharmacol 2017 26;8:641. Epub 2017 Sep 26.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, United States.

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September 2017

Granulocytes as models for human protein marker identification following nicotine exposure.

J Neurochem 2017 08;142 Suppl 2:151-161

Department of Biology, California Institute of Technology, Pasadena, California, USA.

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August 2017

Secondary Ammonium Agonists Make Dual Cation-π Interactions in α4β2 Nicotinic Receptors.

eNeuro 2017 Mar-Apr;4(2). Epub 2017 Mar 30.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.

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July 2018

Menthol Enhances Nicotine Reward-Related Behavior by Potentiating Nicotine-Induced Changes in nAChR Function, nAChR Upregulation, and DA Neuron Excitability.

Neuropsychopharmacology 2017 Nov 2;42(12):2285-2291. Epub 2017 Apr 2.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.

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November 2017