Publications by authors named "Henry A Lester"

174Publications

Directed Evolution of a Selective and Sensitive Serotonin Sensor via Machine Learning.

Authors:
Elizabeth K Unger Jacob P Keller Michael Altermatt Ruqiang Liang Aya Matsui Chunyang Dong Olivia J Hon Zi Yao Junqing Sun Samba Banala Meghan E Flanigan David A Jaffe Samantha Hartanto Jane Carlen Grace O Mizuno Phillip M Borden Amol V Shivange Lindsay P Cameron Steffen Sinning Suzanne M Underhill David E Olson Susan G Amara Duncan Temple Lang Gary Rudnick Jonathan S Marvin Luke D Lavis Henry A Lester Veronica A Alvarez Andrew J Fisher Jennifer A Prescher Thomas L Kash Vladimir Yarov-Yarovoy Viviana Gradinaru Loren L Looger Lin Tian

Cell 2020 Dec 16;183(7):1986-2002.e26. Epub 2020 Dec 16.

Departments of Biochemistry and Molecular Medicine, Chemistry, Statistics, Molecular and Cellular Biology, and Physiology and Membrane Biology, the Center for Neuroscience, and Graduate Programs in Molecular, Cellular, and Integrative Physiology, Biochemistry, Molecular, Cellular and Developmental Biology and Neuroscience, University of California, Davis, Davis, CA 95616, USA. Electronic address:

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December 2020

Proteins for increased surface expression of the α6β4 nicotinic acetylcholine receptor: nothing but good news?

Authors:
Stephen Grant Henry A Lester

J Clin Invest 2020 Nov;130(11):5685-5687

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California, USA.

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November 2020

Biosensors Show the Pharmacokinetics of S-Ketamine in the Endoplasmic Reticulum.

Authors:
Kallol Bera Aron Kamajaya Amol V Shivange Anand K Muthusamy Aaron L Nichols Philip M Borden Stephen Grant Janice Jeon Elaine Lin Ishak Bishara Theodore M Chin Bruce N Cohen Charlene H Kim Elizabeth K Unger Lin Tian Jonathan S Marvin Loren L Looger Henry A Lester

Front Cell Neurosci 2019 12;13:499. Epub 2019 Nov 12.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, United States.

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November 2019

Nicotine Bound to Its Receptors: New Structures for a Vexing Pathopharmacological Problem.

Authors:
Henry A Lester Dennis A Dougherty

Neuron 2019 11;104(3):431-432

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

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November 2019

Brain Region-Specific nAChR and Associated Protein Abundance Alterations Following Chronic Nicotine and/or Menthol Exposure.

Authors:
Matthew J Mulcahy Stephanie M Huard Joao A Paulo Jonathan H Wang Sheri McKinney Brandon J Henderson Henry A Lester

J Proteome Res 2020 01 28;19(1):36-48. Epub 2019 Oct 28.

Division of Biology and Biological Engineering , California Institute of Technology , 1200 East California Boulevard , Pasadena , California 91125-2900 , United States.

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January 2020

Probing Binding Interactions of Cytisine Derivatives to the α4β2 Nicotinic Acetylcholine Receptor.

Authors:
Annet E M Blom Hugo Rego Campello Henry A Lester Timothy Gallagher Dennis A Dougherty

J Am Chem Soc 2019 10 24;141(40):15840-15849. Epub 2019 Sep 24.

School of Chemistry , University of Bristol , Bristol BS8 1TS , United Kingdom.

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October 2019

Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors.

Authors:
Amol V Shivange Philip M Borden Anand K Muthusamy Aaron L Nichols Kallol Bera Huan Bao Ishak Bishara Janice Jeon Matthew J Mulcahy Bruce Cohen Saidhbhe L O'Riordan Charlene Kim Dennis A Dougherty Edwin R Chapman Jonathan S Marvin Loren L Looger Henry A Lester

J Gen Physiol 2019 06 4;151(6):738-757. Epub 2019 Feb 4.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA

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June 2019

Chronic Menthol Does Not Change Stoichiometry or Functional Plasma Membrane Levels of Mouse 34-Containing Nicotinic Acetylcholine Receptors.

Authors:
Selvan Bavan Charlene H Kim Brandon J Henderson Henry A Lester

Mol Pharmacol 2019 04 22;95(4):398-407. Epub 2019 Jan 22.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California (S.B., C.H.K., H.A.L.); and Department of Biomedical Sciences, Joan C. Edwards School of Medicine at Marshall University, Huntington, West Virginia (B.J.H.)

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April 2019

Bidirectional dopamine modulation of excitatory and inhibitory synaptic inputs to subthalamic neuron subsets containing α4β2 or α7 nAChRs.

Authors:
Chunyi Zhou Weixin Gu Haichuan Wu Xiang Yan Purnima Deshpande Cheng Xiao Henry A Lester

Neuropharmacology 2019 04 17;148:220-228. Epub 2019 Jan 17.

Division of Biology, California Institute of Technology, Pasadena, CA, 91125, USA. Electronic address:

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April 2019

Menthol Stereoisomers Exhibit Different Effects on α4β2 nAChR Upregulation and Dopamine Neuron Spontaneous Firing.

Authors:
Brandon J Henderson Stephen Grant Betty W Chu Rezvan Shahoei Stephanie M Huard Shyam S M Saladi Emad Tajkhorshid Dennis A Dougherty Henry A Lester

eNeuro 2018 Nov-Dec;5(6). Epub 2019 Jan 4.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125.

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March 2019

α1-FANGs: Protein Ligands Selective for the α-Bungarotoxin Site of the α1-Nicotinic Acetylcholine Receptor.

Authors:
Aaron L Nichols Kaori Noridomi Christopher R Hughes Farzad Jalali-Yazdi J Brek Eaton Lan Huong Lai Gaurav Advani Ronald J Lukas Henry A Lester Lin Chen Richard W Roberts

ACS Chem Biol 2018 09 13;13(9):2568-2576. Epub 2018 Aug 13.

Department of Chemistry , University of Southern California , Los Angeles , California 90089-1062 , United States.

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September 2018

Chronic nicotine improves cognitive and social impairment in mice overexpressing wild type α-synuclein.

Authors:
Sudhakar R Subramaniam Iddo Magen Nicholas Bove Chunni Zhu Vincent Lemesre Garima Dutta Chris Jean Elias Henry A Lester Marie-Francoise Chesselet

Neurobiol Dis 2018 09 1;117:170-180. Epub 2018 Jun 1.

Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA. Electronic address:

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September 2018

Photoactivatable drugs for nicotinic optopharmacology.

Authors:
Sambashiva Banala Matthew C Arvin Nicholas M Bannon Xiao-Tao Jin John J Macklin Yong Wang Can Peng Guiqing Zhao John J Marshall Kyle R Gee David L Wokosin Veronica J Kim J Michael McIntosh Anis Contractor Henry A Lester Yevgenia Kozorovitskiy Ryan M Drenan Luke D Lavis

Nat Methods 2018 05 26;15(5):347-350. Epub 2018 Mar 26.

Janelia Research Campus, Howard Hughes Medical Institute, Ashburn, Virginia, USA.

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May 2018

Deletion of lynx1 reduces the function of α6* nicotinic receptors.

Authors:
Rell L Parker Heidi C O'Neill Beverley M Henley Charles R Wageman Ryan M Drenan Michael J Marks Julie M Miwa Sharon R Grady Henry A Lester

PLoS One 2017 5;12(12):e0188715. Epub 2017 Dec 5.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, United States of America.

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December 2017

Acute Ethanol Administration Upregulates Synaptic α4-Subunit of Neuronal Nicotinic Acetylcholine Receptors within the Nucleus Accumbens and Amygdala.

Authors:
Josephine R Tarren Henry A Lester Arnauld Belmer Selena E Bartlett

Front Mol Neurosci 2017 24;10:338. Epub 2017 Oct 24.

Translational Research Institute, Institute for Health and Biomedical Innovation, Queensland University of Technology, Brisbane, QLD, Australia.

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October 2017

TC299423, a Novel Agonist for Nicotinic Acetylcholine Receptors.

Authors:
Teagan R Wall Brandon J Henderson George Voren Charles R Wageman Purnima Deshpande Bruce N Cohen Sharon R Grady Michael J Marks Daniel Yohannes Paul J Kenny Merouane Bencherif Henry A Lester

Front Pharmacol 2017 26;8:641. Epub 2017 Sep 26.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, United States.

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September 2017

Granulocytes as models for human protein marker identification following nicotine exposure.

Authors:
Matthew J Mulcahy Henry A Lester

J Neurochem 2017 08;142 Suppl 2:151-161

Department of Biology, California Institute of Technology, Pasadena, California, USA.

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August 2017

TRPV1 regulates excitatory innervation of OLM neurons in the hippocampus.

Authors:
Joaquin I Hurtado-Zavala Binu Ramachandran Saheeb Ahmed Rashi Halder Christiane Bolleyer Ankit Awasthi Markus A Stahlberg Robin J Wagener Kristin Anderson Ryan M Drenan Henry A Lester Julie M Miwa Jochen F Staiger Andre Fischer Camin Dean

Nat Commun 2017 07 19;8:15878. Epub 2017 Jul 19.

Trans-synaptic Signaling Group, European Neuroscience Institute, Grisebachstrasse 5, Goettingen 37077, Germany.

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July 2017

Secondary Ammonium Agonists Make Dual Cation-π Interactions in α4β2 Nicotinic Receptors.

Authors:
Michael R Post Gabrielle S Tender Henry A Lester Dennis A Dougherty

eNeuro 2017 Mar-Apr;4(2). Epub 2017 Mar 30.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125.

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July 2018

Menthol Enhances Nicotine Reward-Related Behavior by Potentiating Nicotine-Induced Changes in nAChR Function, nAChR Upregulation, and DA Neuron Excitability.

Authors:
Brandon J Henderson Teagan R Wall Beverley M Henley Charlene H Kim Sheri McKinney Henry A Lester

Neuropsychopharmacology 2017 Nov 2;42(12):2285-2291. Epub 2017 Apr 2.

Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA.

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November 2017