Henrik Zetterberg

Henrik Zetterberg

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Henrik Zetterberg

Publications by authors named "Henrik Zetterberg"

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Neurofilament light chain as a biomarker in neurological disorders.

J Neurol Neurosurg Psychiatry 2019 Aug 9;90(8):870-881. Epub 2019 Apr 9.

Institute of Neuroscience and Physiology Department of Psychiatry and Neurochemistry, The Sahlgrenska AcademyUniversity of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1136/jnnp-2018-320106DOI Listing
August 2019

CSF neurogranin as a neuronal damage marker in CJD: a comparative study with AD.

J Neurol Neurosurg Psychiatry 2019 Aug 16;90(8):846-853. Epub 2019 May 16.

Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED), Institute Carlos III, Ministry of Health, L'Hospilatet del Llobregat, Barcelona, Spain

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http://dx.doi.org/10.1136/jnnp-2018-320155DOI Listing
August 2019

Detection of α-Synuclein in Biological Samples Using Mass Spectrometry.

Methods Mol Biol 2019 ;1948:209-220

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1007/978-1-4939-9124-2_16DOI Listing
July 2019

Proximity extension assay testing reveals novel diagnostic biomarkers of atypical parkinsonian syndromes.

J Neurol Neurosurg Psychiatry 2019 Jul 13;90(7):768-773. Epub 2019 Mar 13.

Department of Clinical and Movement Neurosciences, UCL Queen Square Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1136/jnnp-2018-320151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585258PMC
July 2019

Heritability and genetic variance of dementia with Lewy bodies.

Neurobiol Dis 2019 07 3;127:492-501. Epub 2019 Apr 3.

Department of Neurodegenerative Diseases, UCL Institute of Neurology, London, UK; UK Dementia Research Institute (UK DRI) at UCL, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588425PMC
July 2019

Exercise as a potential modulator of inflammation in patients with Alzheimer's disease measured in cerebrospinal fluid and plasma.

Exp Gerontol 2019 Jul 11;121:91-98. Epub 2019 Apr 11.

Danish Dementia Research Centre, Department of Neurology, Rigshospitalet University of Copenhagen, DK-2100 Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.exger.2019.04.003DOI Listing
July 2019

Relevance of the interplay between amyloid and tau for cognitive impairment in early Alzheimer's disease.

Neurobiol Aging 2019 07 1;79:131-141. Epub 2019 Apr 1.

Janssen Research and Development, A Division of Janssen Pharmaceutica N.V., Beerse, Belgium; Reference Center for Biological Markers of Dementia (BIODEM), Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.03.016DOI Listing
July 2019

Duration of preclinical, prodromal, and dementia stages of Alzheimer's disease in relation to age, sex, and APOE genotype.

Alzheimers Dement 2019 Jul 1;15(7):888-898. Epub 2019 Jun 1.

Department of Neurology, Alzheimer Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience (MHeNS), Alzheimer Centrum Limburg, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.jalz.2019.04.001DOI Listing
July 2019

Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures.

Neurology 2019 Jul 10;93(3):e252-e260. Epub 2019 Jun 10.

From the Departments of Health Sciences Research (M.M. Mielke, J.A.S., W.K.K., R.C.P., S.K.), Neurology (M.M. Mielke, D.S.K., R.C.P.), Radiology (P.V., C.J.), and Psychiatry and Psychology (M.M. Machulda), Mayo Clinic, Rochester, MN; Department of Psychiatry and Neurochemistry (K.B., H.Z., I.S., S.K.), Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg; Clinical Neurochemistry Laboratory (K.B., H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden; Institute of Neurology (H.Z.), University College London, Queen Square; and UK Dementia Research Institute at UCL (H.Z.), London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000007767DOI Listing
July 2019

Characterization of Cerebrospinal Fluid BACE1 Species.

Mol Neurobiol 2019 Jul 9. Epub 2019 Jul 9.

Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-CSIC, Av. Ramón y Cajal s/n, E-03550, Sant Joan d'Alacant, Spain.

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http://dx.doi.org/10.1007/s12035-019-01677-8DOI Listing
July 2019

Twin study shows association between monocyte chemoattractant protein-1 and kynurenic acid in cerebrospinal fluid.

Eur Arch Psychiatry Clin Neurosci 2019 Jul 13. Epub 2019 Jul 13.

Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, 171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00406-019-01042-9DOI Listing
July 2019

Human cerebrospinal fluid promotes spontaneous gamma oscillations in the hippocampus in vitro.

Hippocampus 2019 Jul 17. Epub 2019 Jul 17.

Neuronal Oscillations Laboratory, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/hipo.23135DOI Listing
July 2019

Synaptic vesicle protein 2A as a potential biomarker in synaptopathies.

Mol Cell Neurosci 2019 Jun 20;97:34-42. Epub 2019 Feb 20.

Wallenberg Centre for Molecular and Translational Medicine, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Sweden; Clinical Memory Research Unit, Lund University, Sweden; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1016/j.mcn.2019.02.001DOI Listing
June 2019

A Serum Protein Biomarker Panel Improves Outcome Prediction in Human Traumatic Brain Injury.

J Neurotrauma 2019 Jun 19. Epub 2019 Jun 19.

10 Department of Physiology and Pharmacology, Section of Perioperative Medicine and Intensive Care, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1089/neu.2019.6375DOI Listing
June 2019

Reduced vascular endothelial growth factor levels in the cerebrospinal fluid in patients with treatment resistant major depression and the effects of electroconvulsive therapy-A pilot study.

J Affect Disord 2019 Jun 18;253:449-453. Epub 2019 Apr 18.

Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim / Heidelberg University, J5, 68159 Mannheim, Germany.

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http://dx.doi.org/10.1016/j.jad.2019.04.080DOI Listing
June 2019

Plasma amyloid β 40/42 ratio predicts cerebral amyloidosis in cognitively normal individuals at risk for Alzheimer's disease.

Alzheimers Dement 2019 Jun 18;15(6):764-775. Epub 2019 May 18.

Sorbonne University, GRC no 21, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Boulevard de l'hôpital, Paris, France.

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http://dx.doi.org/10.1016/j.jalz.2019.03.009DOI Listing
June 2019

Disease signatures: Biomarkers/indicators of neurodegeneration.

Mol Cell Neurosci 2019 Jun 25;97:1-2. Epub 2019 May 25.

University Medical Center, Department of Neurology, Robert-Koch Strasse 40, 37075 Goettingen, Germany.

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https://linkinghub.elsevier.com/retrieve/pii/S10447431193014
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http://dx.doi.org/10.1016/j.mcn.2019.05.004DOI Listing
June 2019

CSF biomarkers distinguish idiopathic normal pressure hydrocephalus from its mimics.

J Neurol Neurosurg Psychiatry 2019 Jun 5. Epub 2019 Jun 5.

Hydrocephalus Research Unit, Department of clinical neuroscience, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1136/jnnp-2019-320826DOI Listing
June 2019

Serum tau concentration after diving - an observational pilot study.

Diving Hyperb Med 2019 Jun;49(2):88-95

Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Gothenburg.

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http://dx.doi.org/10.28920/dhm49.2.88-95DOI Listing
June 2019

Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis.

JAMA Neurol 2019 Jun 17. Epub 2019 Jun 17.

UCL Institute of Neurology, Queen Square, London, United Kingdom.

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http://dx.doi.org/10.1001/jamaneurol.2019.1534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580449PMC
June 2019

Sex Difference in CHI3L1 Expression Levels in Human Brain Aging and in Alzheimer's Disease.

Brain Res 2019 Jun 24:146305. Epub 2019 Jun 24.

Department of Biomedical and Biotechnological Sciences, Human Anatomy and Histology Section, School of Medicine, University of Catania, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2019.146305DOI Listing
June 2019

Evolution and clustering of prodromal parkinsonian features in GBA1 carriers.

Mov Disord 2019 Jun 28. Epub 2019 Jun 28.

Department of Clinical and Movement Neurosciences, University College London Queen Square Institute of Neurology, London, United Kingdom.

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http://dx.doi.org/10.1002/mds.27775DOI Listing
June 2019

Comparison of different MRI-based morphometric estimates for defining neurodegeneration across the Alzheimer's disease continuum.

Neuroimage Clin 2019 Jun 10;23:101895. Epub 2019 Jun 10.

Alzheimer's Disease Research Center, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA; Wisconsin Alzheimer's Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA; Geriatric Research Education and Clinical Center, William S. Middleton Memorial Veterans Hospital, Madison, WI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.nicl.2019.101895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599872PMC
June 2019

Longitudinal tau and metabolic PET imaging in relation to novel CSF tau measures in Alzheimer's disease.

Eur J Nucl Med Mol Imaging 2019 May 4;46(5):1152-1163. Epub 2019 Jan 4.

Department of Neurobiology, Care Sciences and Society, Division of Clinical Geriatrics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00259-018-4242-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6451715PMC
May 2019

Peptidomic analysis of cartilage and subchondral bone in OA patients.

Eur J Clin Invest 2019 May 27;49(5):e13082. Epub 2019 Feb 27.

Department of Orthopaedics, Institute of Clinical Sciences, the Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/eci.13082DOI Listing
May 2019

Comparison of plasma and cerebrospinal fluid neurofilament light in a multiple sclerosis trial.

Acta Neurol Scand 2019 May 5;139(5):462-468. Epub 2019 Mar 5.

Department of Pharmacology and Clinical Neuroscience, Umeå University, Umeå, Sweden.

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http://dx.doi.org/10.1111/ane.13078DOI Listing
May 2019

Cerebrospinal fluid biomarkers for understanding multiple aspects of Alzheimer's disease pathogenesis.

Cell Mol Life Sci 2019 May 15;76(10):1833-1863. Epub 2019 Feb 15.

Centre of Excellence in Alzheimer's Disease Research and Care, School of Medical and Health Sciences, Edith Cowan University, 270 Joondalup Drive, Joondalup, WA, Australia.

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http://dx.doi.org/10.1007/s00018-019-03040-5DOI Listing
May 2019

A distinct brain beta amyloid signature in cerebral amyloid angiopathy compared to Alzheimer's disease.

Neurosci Lett 2019 05 23;701:125-131. Epub 2019 Feb 23.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.

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http://dx.doi.org/10.1016/j.neulet.2019.02.033DOI Listing
May 2019

Ionized calcium in human cerebrospinal fluid and its influence on intrinsic and synaptic excitability of hippocampal pyramidal neurons in the rat.

J Neurochem 2019 May 9;149(4):452-470. Epub 2019 Apr 9.

Department of Physiology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/jnc.14693DOI Listing
May 2019

Mass Spectrometric Analysis of Lewy Body-Enriched α-Synuclein in Parkinson's Disease.

J Proteome Res 2019 May 15;18(5):2109-2120. Epub 2019 Apr 15.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry , Sahlgrenska Academy at the University of Gothenburg , S-431 80 Mölndal , Sweden.

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http://dx.doi.org/10.1021/acs.jproteome.8b00982DOI Listing
May 2019

Sleep deprivation and plasma biomarkers for Alzheimer's disease.

Sleep Med 2019 May 12;57:92-93. Epub 2019 Feb 12.

Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, University of Gothenburg, Sahlgrenska University Hospital, Mölndal, Sweden; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London, UK; UK Dementia Research Institute at UCL, London, UK.

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http://dx.doi.org/10.1016/j.sleep.2018.12.029DOI Listing
May 2019

Identification of neurotoxic cross-linked amyloid-β dimers in the Alzheimer's brain.

Brain 2019 May;142(5):1441-1457

Laboratory for Neurodegenerative Research, Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1093/brain/awz066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487330PMC
May 2019

Breaking the cycle: Reversal of flux in the tricarboxylic acid cycle by dimethyl fumarate.

Neurol Neuroimmunol Neuroinflamm 2019 May 22;6(3):e562. Epub 2019 Apr 22.

Division of Brain Sciences (T.T., R.N., P.M.M.), Department of Medicine, Imperial College, London; St Edmund Hall (C.S., P.M.M.), Oxford University, Oxford, UK; MRC-NIHR National Phenome Centre (M.D., M.G.-R., M.R.L.), Department of Surgery and Cancer, Imperial College; University College London Queen Square Institute of Neurology (A.H., H.Z.); UK Dementia Research Institute, University College London (A.H., H.Z.), London, UK; Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy, the University of Gothenburg; Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden; and UK Dementia Research Institute at Imperial College (P.M.M.), London.

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http://dx.doi.org/10.1212/NXI.0000000000000562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481230PMC
May 2019

NFL is a marker of treatment response in children with SMA treated with nusinersen.

J Neurol 2019 May 23. Epub 2019 May 23.

Queen Silvia Children'S Hospital, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s00415-019-09389-8DOI Listing
May 2019

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2019 May 27. Epub 2019 May 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-019-02026-8DOI Listing
May 2019

Correlations between serum and CSF pNfH levels in ALS, FTD and controls: a comparison of three analytical approaches.

Clin Chem Lab Med 2019 May 9. Epub 2019 May 9.

Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research and Center of Neurology, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1515/cclm-2019-0015DOI Listing
May 2019

Decreased circulating ErbB4 ectodomain fragments as a read-out of impaired signaling function in amyotrophic lateral sclerosis.

Neurobiol Dis 2019 04 27;124:428-438. Epub 2018 Dec 27.

Instituto de Neurociencias de Alicante, Universidad Miguel Hernández-CSIC, Sant Joan d'Alacant, Spain; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Spain. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2018.12.021DOI Listing
April 2019

Neurofilament changes in serum and cerebrospinal fluid after acute ischemic stroke.

Neurosci Lett 2019 04 29;698:58-63. Epub 2018 Dec 29.

Department of Psychiatry & Neurochemistry, University of Gothenburg, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.

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http://dx.doi.org/10.1016/j.neulet.2018.12.042DOI Listing
April 2019

Serum Neurofilament Light Is Elevated Differentially in Older Adults with Uncomplicated Mild Traumatic Brain Injuries.

J Neurotrauma 2019 Apr 23. Epub 2019 Apr 23.

6 Department of Neurosurgery, Tampere University Hospital and University of Tampere, Tampere, Finland.

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https://www.liebertpub.com/doi/10.1089/neu.2018.6341
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http://dx.doi.org/10.1089/neu.2018.6341DOI Listing
April 2019

heterozygosity attenuates -related amyloid burden in preclinical AD.

Neurology 2019 Apr 13;92(16):e1878-e1889. Epub 2019 Mar 13.

From the Geriatric Research Education and Clinical Center (C.L.G., C.M.C., S.A., S.C.J., O.C.O.), William S. Middleton Memorial VA Hospital; Wisconsin Alzheimer's Disease Research Center (C.M.E., J.M.O., Y.M., C.M.C., B.B.B., S.A., B.P.H., M.A.S., C.D.E., B.T.C., S.C.J., O.C.O.); Departments of Population Health Sciences (B.F.D., C.D.E.), Neurology (C.L.G., B.P.H.), Radiology (M.A.S.), Medical Physics (T.B., B.T.C.), and Biostatistics & Medical Informatics (D.N.), University of Wisconsin School of Medicine and Public Health, Madison; Division of Biology and Biomedical Sciences (S.A.S.), Washington University in St. Louis, MO; Department of Psychiatry and Neurochemistry (K.B., H.Z.), Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg; Clinical Neurochemistry Laboratory (K.B., H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden; Institute of Neurology (C.L.G., H.Z.), University College London, Queen Square; UK Dementia Research Institute (H.Z.), London; Wisconsin Alzheimer's Institute (C.M.C., B.B.B., S.A., B.P.H., M.A.S., C.D.E., S.C.J., O.C.O.), Madison; and Department of Neurology and Weill Institute for Neurosciences (D.B.D.), University of California, San Francisco.

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http://dx.doi.org/10.1212/WNL.0000000000007323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6550504PMC
April 2019

Amyloid β42 and Total Tau Levels in Cerebrospinal Fluid Associate with Survival in an 85-Year-Old Population-Based Cohort Followed until Death.

Dement Geriatr Cogn Disord 2019 10;47(1-2):114-124. Epub 2019 Apr 10.

Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1159/000499066DOI Listing
April 2019

Dynamics of extracellular matrix proteins in cerebrospinal fluid and serum and their relation to clinical outcome in human traumatic brain injury.

Clin Chem Lab Med 2019 Apr 15. Epub 2019 Apr 15.

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1515/cclm-2019-0034DOI Listing
April 2019

Association Between Longitudinal Plasma Neurofilament Light and Neurodegeneration in Patients With Alzheimer Disease.

JAMA Neurol 2019 Apr 22. Epub 2019 Apr 22.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1001/jamaneurol.2019.0765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6583067PMC
April 2019

Advantages and disadvantages of the use of the CSF Amyloid β (Aβ) 42/40 ratio in the diagnosis of Alzheimer's Disease.

Alzheimers Res Ther 2019 Apr 22;11(1):34. Epub 2019 Apr 22.

Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1186/s13195-019-0485-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6477717PMC
April 2019

The Cerebrospinal Fluid in Multiple Sclerosis.

Front Immunol 2019 12;10:726. Epub 2019 Apr 12.

Division of Neuroimmunology, Department of Neurology, University Medicine Rostock, Rostock, Germany.

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http://dx.doi.org/10.3389/fimmu.2019.00726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473053PMC
April 2019

Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau.

Neurobiol Aging 2019 Apr 1;80:11-20. Epub 2019 Apr 1.

Department of Biomedical Sciences, Neuroinflammation Group, Centre for Motor Neuron Disease Research, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, New South Wales, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.03.015DOI Listing
April 2019

Muscle and not neuronal biomarkers correlate with severity in spinal and bulbar muscular atrophy.

Neurology 2019 Mar 20;92(11):e1205-e1211. Epub 2019 Feb 20.

From the Institute of Neurology (V.L., O.J.Z., L.Z., C.H., M.F., C.-H.L., B.M., H.Z., A.H., L.G., M.H., P.F.), University College London Institute of Neurology, Queen Square, London; Blizard Institute (V.L., A.M.), Queen Mary, University of London, UK; Department of Neurosciences (G.Q., I.M., C.B., G.S.), University of Padova, Italy; Department of Neurology (C.-H.L.), China Medical University Hospital, Taiwan; Basildon Hospital (K.A.), UK; Department of Physiology, Anatomy and Genetics (C.R.), University of Oxford; UK Dementia Research Institute at UCL (H.Z., A.H.), London, UK; Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital; and the Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000007097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511101PMC
March 2019

Cerebrospinal Fluid Spermidine, Glutamine and Putrescine Predict Postoperative Delirium Following Elective Orthopaedic Surgery.

Sci Rep 2019 Mar 12;9(1):4191. Epub 2019 Mar 12.

Institute for Global Food Security, School of Biological Sciences, Queen's University Belfast, 8 Malone Road, Belfast, BT9 5BN, Northern Ireland.

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http://dx.doi.org/10.1038/s41598-019-40544-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414730PMC
March 2019

Plasma biomarkers for amyloid, tau, and cytokines in Down syndrome and sporadic Alzheimer's disease.

Alzheimers Res Ther 2019 Mar 21;11(1):26. Epub 2019 Mar 21.

Department of Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 16 De Crespigny Park, London, SE5 8AF, UK.

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http://dx.doi.org/10.1186/s13195-019-0477-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429702PMC
March 2019

Blood-based molecular biomarkers for Alzheimer's disease.

Mol Brain 2019 03 28;12(1):26. Epub 2019 Mar 28.

CSIRO Health and Biosecurity, Parkville, Victoria, 3052, Australia.

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http://dx.doi.org/10.1186/s13041-019-0448-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437931PMC
March 2019

HOTMAQ: A Multiplexed Absolute Quantification Method for Targeted Proteomics.

Anal Chem 2019 Feb 18;91(3):2112-2119. Epub 2019 Jan 18.

School of Pharmacy , University of Wisconsin-Madison , Madison , Wisconsin 53705 , United States.

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http://pubs.acs.org/doi/10.1021/acs.analchem.8b04580
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http://dx.doi.org/10.1021/acs.analchem.8b04580DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379083PMC
February 2019

Serum neurofilament light and prediction of multiple sclerosis in clinically isolated syndrome.

Neurology 2019 Feb 11;92(7):313-314. Epub 2019 Jan 11.

From the Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg; Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden; Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square; UK Dementia Research Institute at UCL (H.Z.), London; and Department of Clinical Sciences (A.S.), Danderyd Hospital, Karolinska Institutet, Danderyd Hospital AB, Stockholm, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000006906DOI Listing
February 2019

Cerebrospinal Fluid Concentrations of the Synaptic Marker Neurogranin in Neuro-HIV and Other Neurological Disorders.

Curr HIV/AIDS Rep 2019 Feb;16(1):76-81

Department of Infectious Diseases, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, 416 45, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s11904-019-00420-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6420419PMC
February 2019

Biomarkers for Alzheimer's disease beyond amyloid and tau.

Nat Med 2019 02;25(2):201-203

Dementia Research Centre, Box 16, National Hospital for Neurology and Neurosurgery, London, UK.

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http://dx.doi.org/10.1038/s41591-019-0348-zDOI Listing
February 2019

Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer's disease.

Alzheimers Res Ther 2019 Feb 20;11(1):19. Epub 2019 Feb 20.

Dementia Research Centre, Department of Neurodegenerative Diseases, UCL Institute of Neurology, Queen Square, Box 16, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1186/s13195-019-0472-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6383280PMC
February 2019

Longstanding psychological stress in relation to biomarkers of neuronal dysfunction in cerebrospinal fluid: a 25-year follow-up study in women.

Neurobiol Aging 2019 Feb 27;80:111-115. Epub 2019 Feb 27.

Department of Psychiatry and Neurochemistry, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap), University of Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.02.013DOI Listing
February 2019

CSF concentrations of soluble TREM2 as a marker of microglial activation in HIV-1 infection.

Neurol Neuroimmunol Neuroinflamm 2019 Jan 7;6(1):e512. Epub 2018 Nov 7.

Department of Infectious Diseases (M.G., A.Y., L.-M.A., L.H.), Institute of Biomedicine, the Sahlgrenska Academy at University of Gothenburg, Sweden; Department of Molecular Neuroscience (A.H., E.V., H.Z.), UCL Institute of Neurology, Queen Square; UK Dementia Research Institute at UCL (A.H., E.V., H.Z.), London, United Kingdom; Department of Neurology and Center for Neuroepidemiology and Clinical Neurological Research (S.S.), Yale University, New Haven, CT; Division of Biological Chemistry (D.F.), Biocenter, Medical University of Innsbruck, Austria; Department of Neurology (R.W.P.), University of California San Francisco; Clinical Neurochemistry Laboratory (H.Z.), Sahlgrenska University Hospital; and Department of Psychiatry and Neurochemistry (H.Z.), Institute of Neuroscience and Physiology, the Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1212/NXI.0000000000000512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278890PMC
January 2019

NFL blood levels are moderated by subconcussive impacts in a cohort of college football players.

Brain Inj 2019 11;33(4):456-462. Epub 2019 Jan 11.

d Department of Neuroscience , Lewis Katz School of Medicine at Temple University , Philadelphia , PA , USA.

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https://www.tandfonline.com/doi/full/10.1080/02699052.2019.1
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http://dx.doi.org/10.1080/02699052.2019.1565895DOI Listing
January 2019

Erlangen Score Predicts Cognitive and Neuroimaging Progression in Mild Cognitive Impairment Stage of Alzheimer's Disease.

J Alzheimers Dis 2019 ;69(2):551-559

Department of Psychiatry and Psychotherapy, Universitätsklinikum Erlangen, and Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.3233/JAD-190067DOI Listing
January 2019

Cerebrospinal Fluid Concentrations of Extracellular Matrix Proteins in Alzheimer's Disease.

J Alzheimers Dis 2019 ;69(4):1213-1220

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Sweden.

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http://dx.doi.org/10.3233/JAD-190187DOI Listing
January 2019

The impact of social networks and APOE ε4 on dementia among older adults: tests of possible interactions.

Aging Ment Health 2018 Dec 27:1-10. Epub 2018 Dec 27.

a Department of Sociology and Work Science , University of Gothenburg , Gothenburg , Sweden.

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http://dx.doi.org/10.1080/13607863.2018.1531368DOI Listing
December 2018

Updating Our Definitions of Parkinson's Disease for a Molecular Age.

J Parkinsons Dis 2018 ;8(s1):S53-S57

Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, the Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.3233/JPD-181487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311368PMC
January 2018