Publications by authors named "Henrik Edgren"

37Publications

RET fusions observed in lung and colorectal cancers are sensitive to ponatinib.

Oncotarget 2018 Jul 3;9(51):29654-29664. Epub 2018 Jul 3.

ARIAD Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Ltd, Cambridge, MA, USA.

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http://www.oncotarget.com/fulltext/25664
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http://dx.doi.org/10.18632/oncotarget.25664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049858PMC
July 2018

Case studies investigating genetic heterogeneity between anatomically distinct bone marrow compartments in acute myeloid leukemia.

Leuk Lymphoma 2018 12 4;59(12):3002-3005. Epub 2018 Apr 4.

a Institute for Molecular Medicine Finland, FIMM, University of Helsinki , Helsinki , Finland.

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http://dx.doi.org/10.1080/10428194.2018.1453067DOI Listing
December 2018

Chimeric NUP98-NSD1 transcripts from the cryptic t(5;11)(q35.2;p15.4) in adult de novo acute myeloid leukemia.

Leuk Lymphoma 2018 03 4;59(3):725-732. Epub 2017 Aug 4.

a Institute for Molecular Medicine Finland (FIMM), Helsinki Institute of Life Science , University of Helsinki , Helsinki , Finland.

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http://dx.doi.org/10.1080/10428194.2017.1357174DOI Listing
March 2018

Drug-screening and genomic analyses of HER2-positive breast cancer cell lines reveal predictors for treatment response.

Breast Cancer (Dove Med Press) 2017 21;9:185-198. Epub 2017 Mar 21.

Department of Cancer Genetics, Institute for Cancer Research, Oslo University Hospital; Department of Research, Vestre Viken Hospital Trust, Drammen, Norway.

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http://dx.doi.org/10.2147/BCTT.S115600DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367762PMC
March 2017

Novel TBL1XR1, EPHA7 and SLFN12 mutations in a Sezary syndrome patient discovered by whole exome sequencing.

Exp Dermatol 2014 May;23(5):366-8

Hematology Research Unit Helsinki, Department of Hematology, University of Helsinki and Helsinki University Central Hospital Cancer Center, Helsinki, Finland.

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http://doi.wiley.com/10.1111/exd.12405
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http://dx.doi.org/10.1111/exd.12405DOI Listing
May 2014

Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia.

Cancer Discov 2013 Dec 20;3(12):1416-29. Epub 2013 Sep 20.

1Institute for Molecular Medicine Finland, FIMM; 2Hematology Research Unit Helsinki, Helsinki University Central Hospital, University of Helsinki, Helsinki; 3Department of Clinical Chemistry and TYKSLAB, Turku University Central Hospital, University of Turku, Turku; 4Department of Internal Medicine, Tampere University Hospital, Tampere, Finland; 5Department of Clinical Science, Hematology Section, University of Bergen; and 6Department of Internal Medicine, Hematology Section, Haukeland University Hospital, Bergen, Norway.

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http://dx.doi.org/10.1158/2159-8290.CD-13-0350DOI Listing
December 2013

Aneuploidy facilitates oncogenic transformation via specific genetic alterations, including Twist2 upregulation.

Carcinogenesis 2013 Sep 20;34(9):2000-9. Epub 2013 May 20.

Medical Biotechnology, VTT Technical Research Centre of Finland, FIN-20520 Turku, Finland.

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http://dx.doi.org/10.1093/carcin/bgt171DOI Listing
September 2013

The HER2 amplicon includes several genes required for the growth and survival of HER2 positive breast cancer cells.

Mol Oncol 2013 Jun 24;7(3):392-401. Epub 2012 Nov 24.

Department of Genetics, Institute for Cancer Research, Division of Surgery and Cancer, Oslo University Hospital, Radiumhospitalet, 0310 Oslo, Norway.

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http://dx.doi.org/10.1016/j.molonc.2012.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528495PMC
June 2013

KRAS oncogene rearrangements and gene fusions: unexpected rare encounters in late-stage prostate cancers.

Cancer Discov 2011 Jun 1;1(1):12-3. Epub 2011 Jun 1.

Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland.

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http://cancerdiscovery.aacrjournals.org/lookup/doi/10.1158/2
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http://dx.doi.org/10.1158/2159-8274.CD-11-0045DOI Listing
June 2011

Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis.

Breast Cancer Res Treat 2011 Jan 30;125(2):421-30. Epub 2010 Mar 30.

Medical Biotechnology, VTT Technical Research Center of Finland and Turku Center for Biotechnology, Turku, Finland

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http://link.springer.com/10.1007/s10549-010-0848-5
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http://dx.doi.org/10.1007/s10549-010-0848-5DOI Listing
January 2011

Interactions between Notch- and hypoxia-induced transcriptomes in embryonic stem cells.

Exp Cell Res 2010 May 23;316(9):1610-24. Epub 2009 Dec 23.

Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.yexcr.2009.12.012DOI Listing
May 2010

CIP2A is associated with human breast cancer aggressivity.

Clin Cancer Res 2009 Aug 11;15(16):5092-100. Epub 2009 Aug 11.

Centre for Biotechnology, University of Turku, Turku, Finland.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-3283DOI Listing
August 2009

Integrin trafficking regulated by Rab21 is necessary for cytokinesis.

Dev Cell 2008 Sep;15(3):371-85

Medical Biotechnology, VTT Technical Research Centre of Finland, University of Turku, Turku FIN-20520, Finland.

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http://dx.doi.org/10.1016/j.devcel.2008.08.001DOI Listing
September 2008

A new look towards BAC-based array CGH through a comprehensive comparison with oligo-based array CGH.

BMC Genomics 2007 Mar 29;8:84. Epub 2007 Mar 29.

Laboratoire de Bioinformatique et de Génomique lntégratives, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch CEDEX, France.

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http://bmcgenomics.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2164-8-84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852311PMC
March 2007

Integrated breast cancer genomics.

Cancer Cell 2006 Dec;10(6):453-4

Medical Biotechnology Centre, VTT Technical Research Centre of Finland and University of Turku, 20521 Turku, Finland.

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http://dx.doi.org/10.1016/j.ccr.2006.11.007DOI Listing
December 2006

NMD microarray analysis for rapid genome-wide screen of mutated genes in cancer.

Cell Oncol 2005 ;27(3):169-73

Medical Biotechnology, VTT Technical Research Centre of Finland and University of Turku, FIN-20520 Turku, Finland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617499PMC
http://dx.doi.org/10.1155/2005/478316DOI Listing
December 2005

Optimized LOWESS normalization parameter selection for DNA microarray data.

BMC Bioinformatics 2004 Dec 9;5:194. Epub 2004 Dec 9.

Department of Electrical and Computer Engineering, University of California, Santa Barbara, CA 93106-9560, USA.

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http://dx.doi.org/10.1186/1471-2105-5-194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC539276PMC
December 2004

Are data from different gene expression microarray platforms comparable?

Genomics 2004 Jun;83(6):1164-8

Biomedicum Biochip Center, University of Helsinki, P.O. Box 63, Room A415b, 00014 University of Helsinki, Finland.

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http://dx.doi.org/10.1016/j.ygeno.2004.01.004DOI Listing
June 2004

A novel strategy for microarray quality control using Bayesian networks.

Bioinformatics 2003 Nov;19(16):2031-8

Institute of Signal Processing, Tampere University of Technology, PO Box 553, 33101 Tampere, Finland.

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http://dx.doi.org/10.1093/bioinformatics/btg275DOI Listing
November 2003