Henriette Farkas

Henriette Farkas

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Henriette Farkas

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Hereditary angioedema: examining the landscape of therapies and preclinical therapeutic targets.

Authors:
Henriette Farkas

Expert Opin Ther Targets 2019 Jun 24;23(6):457-459. Epub 2019 Apr 24.

a Hungarian Angioedema Reference Center, Department of Internal Medicine , Semmelweis University , Budapest , Hungary.

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https://www.tandfonline.com/doi/full/10.1080/14728222.2019.1
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http://dx.doi.org/10.1080/14728222.2019.1608949DOI Listing
June 2019

Serum fetuin-A, tumor necrosis factor alpha and C-reactive protein concentrations in patients with hereditary angioedema with C1-inhibitor deficiency.

Orphanet J Rare Dis 2019 Mar 18;14(1):67. Epub 2019 Mar 18.

Department of Family Medicine, Semmelweis University, Budapest POB 2, Kútvölgyi str. 4, Budapest, H-1125, Hungary.

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http://dx.doi.org/10.1186/s13023-019-0995-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6423823PMC
March 2019

Lanadelumab for the Prophylactic Treatment of Hereditary Angioedema with C1 Inhibitor Deficiency: A Review of Preclinical and Phase I Studies.

BioDrugs 2019 Feb;33(1):33-43

Division of Rheumatology, Allergy and Immunology, University of California, San Diego, 8899 University Center Lane, Suite 230, San Diego, CA, 92122, USA.

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http://dx.doi.org/10.1007/s40259-018-0325-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373397PMC
February 2019

Flow-mediated vasodilation assay indicates no endothelial dysfunction in hereditary angioedema patients with C1-inhibitor deficiency.

Ann Allergy Asthma Immunol 2019 Jan 10;122(1):86-92. Epub 2018 Oct 10.

Hungarian Angioedema Reference Center, 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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https://linkinghub.elsevier.com/retrieve/pii/S10811206183129
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http://dx.doi.org/10.1016/j.anai.2018.10.004DOI Listing
January 2019

Targeted next-generation sequencing for the molecular diagnosis of hereditary angioedema due to C1-inhibitor deficiency.

Gene 2018 Aug 16;667:76-82. Epub 2018 May 16.

CeMIA SA, 31 Makrigianni street, GR-41334 Larissa, Greece; Department of Immunology & Histocompatibility, University of Thessaly, School of Health Sciences, Faculty of Medicine, 3 Panepistimiou street, Biopolis, GR-41500 Larissa, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2018.05.029DOI Listing
August 2018

Oral Plasma Kallikrein Inhibitor for Prophylaxis in Hereditary Angioedema.

N Engl J Med 2018 07;379(4):352-362

From the Division of Hematology, Oncology, and Hemostaseology, Department of Children and Adolescents, Angioedema Center, University Hospital Frankfurt (E.A.-P.), and the Fraunhofer Institute for Molecular Biology and Applied Ecology, Translational Medicine and Pharmacology (J. Graff), Frankfurt, the Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Berlin (M. Magerl, M. Maurer), and the Department of Otorhinolaryngology and Head and Neck Surgery, Ulm University Medical Center, Ulm (J. Greve) - all in Germany; the Department of Dermatology and Allergy Center, Odense University Hospital, Odense, Denmark (A.B.); Public Health Institution University Clinic of Dermatology, School of Medicine, University Sts. Cyril and Methodius, Skopje, Macedonia (V.G.-P.); the Department of Clinical Immunology, University Hospital Zurich, Zurich, Switzerland (U.C.S.); Assistance Publique-Hôpitaux de Paris Hôpital Saint Antoine, Sorbonne Université, Paris (O.F.), and the Department of Dermatology, Université de Montpellier, Montpellier (A.D.-T.) - both in France; the Allergy and Immunology West Midlands, Birmingham Heartlands Hospital, Birmingham (A.H.), Barts Health NHS Trust-Royal London Hospital, London (H.J.L.), the National Institute for Health Research Southampton Clinical Research Facility, Southampton (W.R.), and the North Bristol NHS Trust, Southmead Hospital, Bristol (M. Gompels) - all in the United Kingdom; the Department of Dermatology, Medical University of Vienna, Vienna (T.K.), and the Department of Dermatology and Venereology, Medical University of Graz, Graz (W.A.) - both in Austria; the Hungarian Angioedema Reference Center, 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary (H.F.); the Allergology Unit, Department of Internal Medicine, Hospital Universitario Bellvitge de L'Hospitalet de Llobregat (R.L.) and Hospital Universitari Vall d'Hebron, Vall d'Hebron Research Institute (M. Guilarte), Barcelona, Hospital General Universitario Gregorio Marañón, Biomedical Research Network on Rare Diseases (Centro de Investigación Biomédica en Red de Enfermedades Raras)-Unit 761, Institute for Health Research, Gregorio Marañon, Madrid (M.L.B.), and Hospital Universitario Virgen del Rocío, Seville (T.G.-Q.) - all in Spain; the Division of Allergy and Clinical Immunology, University of Salerno, Salerno (M.T.), the Department of Medicine, University of Padua, Padua (M. Cancian), and Azienda Socio Sanitaria Territoriale Fatebenefratelli Sacco-Università degli Studi di Milano, Milan (A.Z., M. Cicardi) - all in Italy; the Department of Clinical Immunology and Allergy, Royal Adelaide Hospital, Adelaide, SA (W.B.S.), and Campbelltown Hospital, Immunology and Allergy, Western Sydney University, Sydney (C.K.) - both in Australia; and BioCryst Pharmaceuticals (S.D., M. Cornpropst, D.C., P.C., W.S.) and PharStat (L.F.) - both in Durham, NC.

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http://dx.doi.org/10.1056/NEJMoa1716995DOI Listing
July 2018

Treatment Effect and Safety of Icatibant in Pediatric Patients with Hereditary Angioedema.

J Allergy Clin Immunol Pract 2017 Nov - Dec;5(6):1671-1678.e2. Epub 2017 Jun 7.

Institute for Asthma and Allergy, Chevy Chase, Md.

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http://dx.doi.org/10.1016/j.jaip.2017.04.010DOI Listing
June 2018

Icatibant for the treatment of hereditary angioedema with C1-inhibitor deficiency in adolescents and in children aged over 2 years.

Expert Rev Clin Immunol 2018 06 24;14(6):447-460. Epub 2018 May 24.

a Hungarian Angioedema Reference Center, 3rd Department of Internal Medicine , Semmelweis University , Budapest , Hungary.

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http://dx.doi.org/10.1080/1744666X.2018.1476851DOI Listing
June 2018

Pharmacological Management of Hereditary Angioedema with C1-Inhibitor Deficiency in Pediatric Patients.

Authors:
Henriette Farkas

Paediatr Drugs 2018 Apr;20(2):135-151

3rd Department of Internal Medicine, Hungarian Angioedema Center, Semmelweis University, Kútvölgyi street 4, Budapest, 1125, Hungary.

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http://link.springer.com/10.1007/s40272-017-0273-x
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http://dx.doi.org/10.1007/s40272-017-0273-xDOI Listing
April 2018

Idiopathic Nonhistaminergic Acquired Angioedema Versus Hereditary Angioedema.

J Allergy Clin Immunol Pract 2018 Jul - Aug;6(4):1205-1208. Epub 2018 Apr 30.

Hungarian Angioedema Center, 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2018.04.018DOI Listing
April 2018

Investigational drugs in phase I and phase II clinical trials for hereditary angioedema.

Expert Opin Investig Drugs 2018 01 15;27(1):87-103. Epub 2017 Dec 15.

a Hungarian Angioedema Center, 3rd Department of Internal Medicine , Semmelweis University , Budapest , Hungary.

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http://dx.doi.org/10.1080/13543784.2018.1415325DOI Listing
January 2018

Cleaved kininogen as a biomarker for bradykinin release in hereditary angioedema.

J Allergy Clin Immunol 2017 12 4;140(6):1700-1703.e8. Epub 2017 Aug 4.

Department of Clinical Chemistry and Haematology, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.07.012DOI Listing
December 2017

Genetic Determinants of C1 Inhibitor Deficiency Angioedema Age of Onset.

Int Arch Allergy Immunol 2017 9;174(3-4):200-204. Epub 2017 Nov 9.

Department of Immunology and Histocompatibility, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece.

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http://dx.doi.org/10.1159/000481987DOI Listing
December 2017

The relationship between anxiety and quality of life in children with hereditary angioedema.

Pediatr Allergy Immunol 2017 Nov 11;28(7):692-698. Epub 2017 Aug 11.

Occupational Therapy Department, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel.

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http://dx.doi.org/10.1111/pai.12758DOI Listing
November 2017

A novel prophylaxis with C1-inhibitor concentrate in hereditary angioedema during erythema marginatum.

Immunol Lett 2017 09 31;189:90-93. Epub 2017 May 31.

Hungarian Angioedema Center, 3(rd) Department of Internal Medicine, Semmelweis University, Kútvölgyi street 4, Budapest, H-1125, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.imlet.2017.05.015DOI Listing
September 2017

The role of the complement system in hereditary angioedema.

Mol Immunol 2017 09 7;89:59-68. Epub 2017 Jun 7.

3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.molimm.2017.05.020DOI Listing
September 2017

[Effect of danazol treatment on growth in pediatric patients with hereditary angioedema due to C1-inhibitor deficiency].

Orv Hetil 2017 Aug;158(32):1269-1276

III. Belgyógyászati Klinika, Országos Angiooedema Központ, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest, Kútvölgyi út 4., 1125.

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http://dx.doi.org/10.1556/650.2017.30806DOI Listing
August 2017

Health-related quality of life among children with hereditary angioedema.

Pediatr Allergy Immunol 2017 06 4;28(4):370-376. Epub 2017 Apr 4.

Division of Allergy and Clinical Immunology, Technion Faculty of Medicine, Bnai Zion Medical Center, Haifa, Israel.

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http://dx.doi.org/10.1111/pai.12712DOI Listing
June 2017

Reply.

J Allergy Clin Immunol 2017 05 16;139(5):1720-1721. Epub 2017 Mar 16.

Department of Medicine, Medical University of South Carolina, Charleston, SC.

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http://dx.doi.org/10.1016/j.jaci.2016.12.983DOI Listing
May 2017

Prevention of Hereditary Angioedema Attacks with a Subcutaneous C1 Inhibitor.

N Engl J Med 2017 03;376(12):1131-1140

From Barts Health NHS Trust (H.L.) and St. John's Institute of Dermatology, Guy's Hospital (C.G.), London, and the Clinical Investigation and Research Unit, Royal Sussex County Hospital, Brighton (M.T.) - all in the United Kingdom; Ospedale Luigi Sacco-U.O. Medicina Generale, Milan (M.C.), and the Department of Internal Medicine, University of Catania, Catania (S.N.) - both in Italy; Department of Medicine and Pediatrics, Penn State Hershey Allergy, Asthma, and Immunology, Hershey (T. Craig), and CSL Behring, King of Prussia (D.B.-K., J.E., D.P.) - both in Pennsylvania; the Department of Dermatology, Johannes Gutenberg University Mainz, Mainz (K.B.), and CSL Behring, Marburg (H. Feuersenger, J.-P.L., T.M., I.P.) - both in Germany; Baker Allergy, Asthma and Dermatology Research Center, Portland, OR (J. Baker); Institute for Asthma and Allergy, Chevy Chase, MD (H.H.L.); Allergy and Immunology Unit, Chaim Sheba Medical Center, Tel Hashomer (A.R.), and Allergy and Immunology Unit, Tel Aviv Sourasky Medical Center, Tel Aviv (S.K.) - both in Israel; Clinical Research Center of Alabama, Birmingham (J. Bonner, J.A.); Department of Internal Medicine, Allergy Section Cincinnati, University of Cincinnati College of Medicine, Cincinnati (J.A.B.), and Toledo Institute of Clinical Research, Toledo (S.M.R.) - both in Ohio; Allergy Asthma Research Associates Research Center, Dallas (W.R.L.); Hungarian Angioedema Center, Third Department of Internal Medicine, Semmelweis University, Budapest (H. Farkas); the Department of Medicine, Immunology, and Allergy, Campbelltown Hospital, Campbelltown, NSW, Australia (C.H.K.); the Department of Clinical Immunology and Allergy, St. Michael's Hospital, Toronto (G.L.S.), Centre de Recherche Appliqué en Allergie de Québec, Quebec, QC (J.H.), McMaster University, Hamilton, ON (P.K.K.), Ottawa Allergy Research and University of Ottawa Medical School, Ottawa (W.Y.), and University of Alberta Hospital, Edmonton (B.R.) - all in Canada; Allergy and Asthma Clinical Research, Walnut Creek (J.J.), University of California, San Diego School of Medicine, La Jolla (M.R., B.L.Z.), and 705 W. La Veta Ave., Suite 101, Orange (D.S.L.) - all in California; Medical Research of Arizona, Scottsdale (M.E.M.); Hospital General Universitario Gregorio Marañón and Biomedical Research Network on Rare Diseases-U761, Institute for Health Research, Gregorio Marañón (M.L.B.), and the Allergy Department, Hospital La Paz Institute for Health Research, Biomedical Research Network on Rare Diseases (T. Caballero), Madrid, the Allergy Department, IIS Hospital Universitario La Fe, Valencia (M.D.H.), and Hospital Universitario Vall d'Hebron, Barcelona (M.G.) - all in Spain; Asthma and Allergy Association, Colorado Springs, CO (R.N.); Department of Internal Medicine, Virginia Commonwealth University, Richmond (L.B.S.); Spitalul Clinic Municipal, Cluj-Napoca, Romania (I.C.); Vital Prospects Clinical Research Institute, Tulsa, OK (I.H.); Institute of Clinical Immunology and Allergology, University Hospital, Hradec Kralove, Czech Republic (P.K.); Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston (A.B.); and Marycliff Allergy Specialists, Spokane, WA (R.G.G.).

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http://dx.doi.org/10.1056/NEJMoa1613627DOI Listing
March 2017

Glucocorticoid receptor gene polymorphisms in hereditary angioedema with C1-inhibitor deficiency.

Orphanet J Rare Dis 2017 01 10;12(1). Epub 2017 Jan 10.

Hungarian Angioedema Center, 3rd Department of Internal Medicine, Semmelweis University, Kútvölgyi street 4, H-1125, Budapest, Hungary.

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http://dx.doi.org/10.1186/s13023-016-0552-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223456PMC
January 2017

Risk of thromboembolism in patients with hereditary angioedema treated with plasma-derived C1-inhibitor.

Allergy Asthma Proc 2016 Mar-Apr;37(2):164-70. Epub 2016 Jan 21.

Hungarian Angioedema Center, 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.2500/aap.2016.37.3933DOI Listing
December 2016

"Nuts and Bolts" of Laboratory Evaluation of Angioedema.

Clin Rev Allergy Immunol 2016 Oct;51(2):140-51

Research Laboratory, 3rd Department of Internal Medicine, Semmelweis University, Kútvölgyi út 4, H-1125, Budapest, Hungary.

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http://dx.doi.org/10.1007/s12016-016-8539-6DOI Listing
October 2016

First report of icatibant treatment in a pregnant patient with hereditary angioedema.

J Obstet Gynaecol Res 2016 Aug 19;42(8):1026-8. Epub 2016 Apr 19.

Hungarian Angioedema Center, Third Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1111/jog.13003DOI Listing
August 2016

Thyroid hormones and complement parameters in hereditary angioedema with C1-inhibitor deficiency.

Ann Allergy Asthma Immunol 2016 08 28;117(2):175-9. Epub 2016 Jun 28.

3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.anai.2016.06.005DOI Listing
August 2016

Icatibant as acute treatment for hereditary angioedema in adults.

Authors:
Henriette Farkas

Expert Rev Clin Pharmacol 2016 Jun 13;9(6):779-88. Epub 2016 May 13.

a Hungarian Angioedema Center, 3rd Department of Internal Medicine , Semmelweis University , Budapest , Hungary.

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http://dx.doi.org/10.1080/17512433.2016.1182425DOI Listing
June 2016

Atrial natriuretic peptide as a novel biomarker of hereditary angioedema.

Clin Immunol 2016 Apr 4;165:45-6. Epub 2016 Mar 4.

3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.clim.2016.03.007DOI Listing
April 2016

Icatibant for Multiple Hereditary Angioedema Attacks across the Controlled and Open-Label Extension Phases of FAST-3.

Int Arch Allergy Immunol 2015 11;168(1):44-55. Epub 2015 Nov 11.

AARA Research Center, Dallas, Tex., USA.

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http://dx.doi.org/10.1159/000441060DOI Listing
February 2016

Erythema Marginatum as an Early Symptom of Hereditary Angioedema: Case Report of 2 Newborns.

Pediatrics 2016 Feb 12;137(2):e20152411. Epub 2016 Jan 12.

Hungarian Angioedema Center, 3rd Department of Internal Medicine, Semmelweis University, Hungary.

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http://pediatrics.aappublications.org/content/pediatrics/ear
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http://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2
Publisher Site
http://dx.doi.org/10.1542/peds.2015-2411DOI Listing
February 2016

Novel Vasoregulatory Aspects of Hereditary Angioedema: the Role of Arginine Vasopressin, Adrenomedullin and Endothelin-1.

J Clin Immunol 2016 Feb 12;36(2):160-70. Epub 2016 Feb 12.

3rd Department of Internal Medicine, Semmelweis University, Kútvölgyi út 4., Budapest, H-1125, Hungary.

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http://dx.doi.org/10.1007/s10875-016-0239-8DOI Listing
February 2016

The effect of long-term danazol treatment on haematological parameters in hereditary angioedema.

Orphanet J Rare Dis 2016 Feb 25;11:18. Epub 2016 Feb 25.

Hungarian Angioedema Centre, 3rd Department of Internal Medicine, Semmelweis University, Kútvölgyi street 4, H-1125, Budapest, Hungary.

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http://dx.doi.org/10.1186/s13023-016-0386-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766663PMC
February 2016

Neutrophil activation during attacks in patients with hereditary angioedema due to C1-inhibitor deficiency.

Orphanet J Rare Dis 2015 Dec 10;10:156. Epub 2015 Dec 10.

Hungarian Angioedema Center, 3rd Department of Internal Medicine, Semmelweis University, Kútvölgyi út 4, H-1125, Budapest, Hungary.

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http://dx.doi.org/10.1186/s13023-015-0374-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674948PMC
December 2015

Common genetic variants of the human steroid 21-hydroxylase gene (CYP21A2) are related to differences in circulating hormone levels.

PLoS One 2014 11;9(9):e107244. Epub 2014 Sep 11.

Molecular Medicine Research Group, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary; "Lendület" Hereditary Endocrine Tumours Research Group, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107244PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161435PMC
October 2015

The Levels of the Lectin Pathway Serine Protease MASP-1 and Its Complex Formation with C1 Inhibitor Are Linked to the Severity of Hereditary Angioedema.

J Immunol 2015 Oct 14;195(8):3596-604. Epub 2015 Sep 14.

Laboratory of Molecular Medicine, Department of Clinical Immunology, Faculty of Health and Medical Sciences, University Hospital of Copenhagen, 2200 Copenhagen, Denmark;

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http://dx.doi.org/10.4049/jimmunol.1402838DOI Listing
October 2015

Comprehensive study into the activation of the plasma enzyme systems during attacks of hereditary angioedema due to C1-inhibitor deficiency.

Orphanet J Rare Dis 2015 Oct 9;10:132. Epub 2015 Oct 9.

3rd Department of Internal Medicine, Semmelweis University, Faculty of Medicine, Kútvölgyi út 4, H-1125, Budapest, Hungary.

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http://dx.doi.org/10.1186/s13023-015-0351-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4600308PMC
October 2015

Hereditary angioedema: molecular and clinical differences among European populations.

J Allergy Clin Immunol 2015 Feb 23;135(2):570-3. Epub 2014 Sep 23.

Department of Immunology and Histocompatibility, University of Thessaly, School of Health Sciences, Faculty of Medicine, Larissa, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.08.007DOI Listing
February 2015

Diagnosis and treatment of bradykinin-mediated angioedema: outcomes from an angioedema expert consensus meeting.

Int Arch Allergy Immunol 2014 15;165(2):119-27. Epub 2014 Nov 15.

Penn State University, Hershey Medical Center, Hershey, Pa., USA.

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https://www.karger.com/Article/FullText/368404
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http://dx.doi.org/10.1159/000368404DOI Listing
February 2015

Successful prophylaxis with recombinant human C1 inhibitor in a patient with hereditary angioedema.

Ann Allergy Asthma Immunol 2015 Jan 6;114(1):64-5. Epub 2014 Nov 6.

National Angioedema Center, Third Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.anai.2014.10.002DOI Listing
January 2015

Home treatment of attacks with conestat alfa in hereditary angioedema due to C1-inhibitor deficiency.

Allergy Asthma Proc 2014 May-Jun;35(3):255-9

Third Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.2500/aap.2014.35.3743DOI Listing
December 2014

Activation of the ficolin-lectin pathway during attacks of hereditary angioedema.

J Allergy Clin Immunol 2014 Dec 16;134(6):1388-1393.e1. Epub 2014 Jul 16.

Laboratory of Molecular Medicine, Faculty of Health Sciences, Department of Clinical Immunology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.jaci.2014.05.030DOI Listing
December 2014

Frequency of the virilising effects of attenuated androgens reported by women with hereditary angioedema.

Orphanet J Rare Dis 2014 Dec 5;9:205. Epub 2014 Dec 5.

3rd Department of Internal Medicine, Semmelweis University, Kútvölgyi út 4, Budapest, H-1125, Hungary.

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http://dx.doi.org/10.1186/s13023-014-0205-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268897PMC
December 2014

Short-term prophylaxis in a patient with acquired C1-INH deficiency.

J Allergy Clin Immunol 2014 Aug 24;134(2):478-80. Epub 2014 Apr 24.

National Angioedema Center, 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.jaci.2014.03.008DOI Listing
August 2014

Reply: To PMID 24522092.

J Allergy Clin Immunol 2014 Jul 27;134(1):241-2. Epub 2014 May 27.

3rd Department of Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.jaci.2014.04.017DOI Listing
July 2014

Endothelial cell activation during edematous attacks of hereditary angioedema types I and II.

J Allergy Clin Immunol 2014 Jun 9;133(6):1686-91. Epub 2014 Feb 9.

3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2013.12.1072DOI Listing
June 2014

Novel duplication in the F12 gene in a patient with recurrent angioedema.

Clin Immunol 2013 Oct 9;149(1):142-5. Epub 2013 Aug 9.

3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.clim.2013.08.001DOI Listing
October 2013

The role of ficolins and MASPs in hereditary angioedema due to C1-inhibitor deficiency.

Mol Immunol 2013 Jul 12;54(3-4):271-7. Epub 2013 Jan 12.

3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.molimm.2012.12.015DOI Listing
July 2013

An abdominal attack of hereditary angio-oedema.

Lancet 2013 Apr 16;381(9875):1404. Epub 2012 Nov 16.

3rd Department of Internal Medicine Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/S0140-6736(12)61146-5DOI Listing
April 2013

Current pharmacotherapy of bradykinin-mediated angioedema.

Authors:
Henriette Farkas

Expert Opin Pharmacother 2013 Apr;14(5):571-86

Semmelweis University, 3rd Department of Internal Medicine, Faculty of Medicine, H-1125 Budapest, Kútvölgyiút 4, Hungary.

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http://dx.doi.org/10.1517/14656566.2013.778826DOI Listing
April 2013

Prophylactic therapy in children with hereditary angioedema.

J Allergy Clin Immunol 2013 Feb 24;131(2):579-82.e1-2. Epub 2012 Sep 24.

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http://dx.doi.org/10.1016/j.jaci.2012.08.001DOI Listing
February 2013

Endothelial cell function in patients with hereditary angioedema: elevated soluble E-selectin level during inter-attack periods.

J Clin Immunol 2012 Feb 19;32(1):61-9. Epub 2011 Oct 19.

Research Laboratory, 3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1007/s10875-011-9606-7DOI Listing
February 2012

Strong correlation of high EBNA-1-IgG levels with edematous attacks involving upper airway mucosa in hereditary angioedema due to C1-inhibitor deficiency.

Mol Immunol 2012 Jan 3;49(4):649-54. Epub 2011 Dec 3.

3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.molimm.2011.11.005DOI Listing
January 2012

Ecallantide is a novel treatment for attacks of hereditary angioedema due to C1 inhibitor deficiency.

Clin Cosmet Investig Dermatol 2011 31;4:61-8. Epub 2011 May 31.

3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.2147/CCID.S10322DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133501PMC
November 2011

Lack of increased prevalence of immunoregulatory disorders in hereditary angioedema due to C1-inhibitor deficiency.

Clin Immunol 2011 Oct 19;141(1):58-66. Epub 2011 May 19.

Semmelweis University, 3rd Department of Internal Medicine, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.clim.2011.05.004DOI Listing
October 2011

Successful outcome using C1-inhibitor concentrate in acute pancreatitis caused by hereditary angioedema.

Gastroenterol Nurs 2011 Jan-Feb;34(1):60-3

Semmelweis University, 3rd Department of Internal Medicine, Budapest, Hungary.

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http://dx.doi.org/10.1097/SGA.0b013e31820b269cDOI Listing
June 2011

Parameters of the classical complement pathway predict disease severity in hereditary angioedema.

Clin Immunol 2011 Apr 20;139(1):85-93. Epub 2011 Jan 20.

3rd Department of Internal Medicine, Semmelweis University Budapest, Kútvölgyi Str 4, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.clim.2011.01.003DOI Listing
April 2011

Long-term efficacy of danazol treatment in hereditary angioedema.

Eur J Clin Invest 2011 Mar 18;41(3):256-62. Epub 2010 Oct 18.

3rd Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1111/j.1365-2362.2010.02402.xDOI Listing
March 2011

rhC1INH: a new drug for the treatment of attacks in hereditary angioedema caused by C1-inhibitor deficiency.

Expert Rev Clin Immunol 2011 Mar;7(2):143-53

3rd Department of Internal Medicine, Semmelweis University Budapest, H-1125 Kútvölgyi street 4, Budapest, Hungary.

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http://dx.doi.org/10.1586/eci.11.5DOI Listing
March 2011

Treatment with C1-inhibitor concentrate does not induce IgM type anti-C1 inhibitor antibodies in patients with hereditary angioedema.

Mol Immunol 2011 Jan 15;48(4):572-6. Epub 2010 Dec 15.

3rd Department of Internal Medicine, Semmelweis University, Kútvölgyi Str 4, H-1125 Budapest, Hungary.

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http://dx.doi.org/10.1016/j.molimm.2010.10.012DOI Listing
January 2011

The natural history of hereditary angioedema and the impact of treatment with human C1-inhibitor concentrate during pregnancy: a long-term survey.

Eur J Obstet Gynecol Reprod Biol 2010 Sep 11;152(1):44-9. Epub 2010 Jun 11.

Semmelweis University, 3rd Department of Internal Medicine, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.ejogrb.2010.05.008DOI Listing
September 2010

Pediatric hereditary angioedema due to C1-inhibitor deficiency.

Authors:
Henriette Farkas

Allergy Asthma Clin Immunol 2010 Jul 28;6(1):18. Epub 2010 Jul 28.

3rd Department of Internal Medicine, Faculty of Medicine, Semmelweis University, H-1125 Budapest, Kútvölgyi út 4, Hungary.

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http://aacijournal.biomedcentral.com/articles/10.1186/1710-1
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http://dx.doi.org/10.1186/1710-1492-6-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920237PMC
July 2010

Management of upper airway edema caused by hereditary angioedema.

Authors:
Henriette Farkas

Allergy Asthma Clin Immunol 2010 Jul 28;6(1):19. Epub 2010 Jul 28.

3rd Department of Internal Medicine, Faculty of Medicine, Semmelweis University, H-1125 Budapest, Kútvölgyi út 4, Hungary.

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http://dx.doi.org/10.1186/1710-1492-6-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2920238PMC
July 2010

Baseline level of functional C1-inhibitor correlates with disease severity scores in hereditary angioedema.

Clin Immunol 2010 Mar 27;134(3):354-8. Epub 2009 Nov 27.

Department of Internal Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1016/j.clim.2009.11.002DOI Listing
March 2010

Disease expression in women with hereditary angioedema.

Am J Obstet Gynecol 2008 Nov 13;199(5):484.e1-4. Epub 2008 Jun 13.

Department of Internal Medicine, Grenoble University Hospital, Grenoble, France.

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http://dx.doi.org/10.1016/j.ajog.2008.04.034DOI Listing
November 2008

Treatment of type I and II hereditary angioedema with Rhucin, a recombinant human C1 inhibitor.

Expert Rev Clin Immunol 2008 Nov;4(6):653-61

3rd Department of Internal Medicine, Semmelweis University Budapest, H-1125 Kútvölgyi Street 4, Budapest, Hungary.

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http://dx.doi.org/10.1586/1744666X.4.6.653DOI Listing
November 2008

Acquired angioedema associated with primary antiphospholipid syndrome in a patient with antithrombin III deficiency.

Int Arch Allergy Immunol 2008 18;146(2):164-8. Epub 2008 Jan 18.

Third Department of Internal Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1159/000113521DOI Listing
June 2008

Anti-cholesterol antibody levels in hereditary angioedema.

J Cell Mol Med 2007 Nov-Dec;11(6):1377-83

Third Department of Internal Medicine, Faculty of Medicine, Semmelweis University, Budapest, Hungary.

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http://dx.doi.org/10.1111/j.1582-4934.2007.00124.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401298PMC
June 2008