Henning Walczak

Henning Walczak

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Henning Walczak

Publications by authors named "Henning Walczak"

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M1-linked ubiquitination by LUBEL is required for inflammatory responses to oral infection in Drosophila.

Cell Death Differ 2019 May 19;26(5):860-876. Epub 2018 Jul 19.

Department of Cell Biology, Faculty of Science and Engineering, BioCity, Åbo Akademi University, 20520, Turku, Finland.

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http://www.nature.com/articles/s41418-018-0164-x
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http://dx.doi.org/10.1038/s41418-018-0164-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6462001PMC
May 2019

Characterization of the TNFR1-SC Using "Modified Tandem Affinity Purification" in Conjunction with Liquid Chromatography-Mass Spectrometry (LC-MS).

Methods Mol Biol 2018 ;1857:161-169

Centre for Cell Death, Cancer and Inflammation (CCCI), UCL Cancer Institute, University College London, London, UK.

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http://dx.doi.org/10.1007/978-1-4939-8754-2_16DOI Listing
May 2019

Cell Death and Inflammation - A Vital but Dangerous Liaison.

Trends Immunol 2019 May 16;40(5):387-402. Epub 2019 Apr 16.

Centre for Cell Death, Cancer, and Inflammation, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6BT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.it.2019.03.006DOI Listing
May 2019

Linear ubiquitination at a glance.

J Cell Sci 2019 01 18;132(2). Epub 2019 Jan 18.

Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK

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http://dx.doi.org/10.1242/jcs.208512DOI Listing
January 2019

Endothelial Cell Killing by TAK1 Inhibition: A Novel Anti-angiogenic Strategy in Cancer Therapy.

Dev Cell 2019 01;48(2):127-128

Centre for Cell Death, Cancer and Inflammation, UCL Cancer Institute, University College London, WC1E 6DD London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2019.01.011DOI Listing
January 2019

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Sterile Inflammation Fuels Gastric Cancer.

Immunity 2018 03;48(3):481-483

Centre for Cell Death, Cancer and Inflammation (CCCI), UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.03.011DOI Listing
March 2018

Paving TRAIL's Path with Ubiquitin.

Trends Biochem Sci 2018 01 28;43(1):44-60. Epub 2017 Nov 28.

Centre for Cell Death, Cancer, and Inflammation, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.tibs.2017.11.002DOI Listing
January 2018

The Linear ubiquitin chain assembly complex acts as a liver tumor suppressor and inhibits hepatocyte apoptosis and hepatitis.

Hepatology 2017 06 10;65(6):1963-1978. Epub 2017 Apr 10.

Centre for Cell Death, Cancer and Inflammation, UCL Cancer Institute, University College London, London, UK.

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http://dx.doi.org/10.1002/hep.29074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485060PMC
June 2017

Exploring the TRAILs less travelled: TRAIL in cancer biology and therapy.

Nat Rev Cancer 2017 05;17(6):352-366

Centre for Cell Death, Cancer and Inflammation, UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK.

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http://www.nature.com/doifinder/10.1038/nrc.2017.28
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http://dx.doi.org/10.1038/nrc.2017.28DOI Listing
May 2017

TLRs Go Linear - On the Ubiquitin Edge.

Trends Mol Med 2017 04 18;23(4):296-309. Epub 2017 Mar 18.

Centre for Cell Death, Cancer, and Inflammation (CCCI), University College London (UCL) Cancer Institute, 72 Huntley Street, London WC1E 6DD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2017.02.003DOI Listing
April 2017

The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2.

Mol Cell 2017 Feb;65(4):730-742.e5

Centre for Cell Death, Cancer, and Inflammation, Department of Cancer Biology, UCL Cancer Institute, University College London, London WC1E 6DD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.01.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5316415PMC
February 2017

Zebrafish Model for Functional Screening of Flow-Responsive Genes.

Arterioscler Thromb Vasc Biol 2017 01 10;37(1):130-143. Epub 2016 Nov 10.

From the Department of Infection, Immunity and Cardiovascular Disease (J.S.-C., L.A.L., S.H., I.G., M.M., S.F., C.S., N.B., J.-P.A., V.R., T.J.A.C., P.C.E.), INSIGNEO Institute for In Silico Medicine (J.S.-C., V.R., T.J.A.C., P.C.E.), and the Bateson Centre (J.S.-C., J.-P.A., T.J.A.C., P.C.E.), University of Sheffield, United Kingdom; and Departments of Cardiovascular Science (A.d.L., C.W., J.C.M., D.O.H.), Imaging (P.F.F., D.F.), Bioengineering (R.K.), and Aeronautics (S.S.) Imperial College London, United Kingdom; and Cancer Institute, Faculty of Medical Sciences (H.W.), University College London, United Kingdom.

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http://atvb.ahajournals.org/content/atvbaha/37/1/130.full.pd
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http://atvb.ahajournals.org/lookup/doi/10.1161/ATVBAHA.116.3
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http://dx.doi.org/10.1161/ATVBAHA.116.308502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5172514PMC
January 2017

Martin Leverkus, 1965-2016.

Cell Death Discov 2017 23;3:16093. Epub 2017 Jan 23.

DKFZ , Heidelberg, Germany.

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http://dx.doi.org/10.1038/cddiscovery.2016.93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5253417PMC
January 2017

Opposing role of tumor necrosis factor receptor 1 signaling in T cell-mediated hepatitis and bacterial infection in mice.

Hepatology 2016 08 18;64(2):508-21. Epub 2016 Apr 18.

I. Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

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http://dx.doi.org/10.1002/hep.28551DOI Listing
August 2016

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.

Cell Rep 2016 08 18;16(9):2271-80. Epub 2016 Aug 18.

Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2016.07.086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009064PMC
August 2016

NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II.

Cell Death Dis 2016 08 25;7(8):e2346. Epub 2016 Aug 25.

Institute of Genetics and Biophysics 'Adriano Buzzati-Traverso' (CNR), Naples 80131, Italy.

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http://dx.doi.org/10.1038/cddis.2016.245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108330PMC
August 2016

Formation and removal of poly-ubiquitin chains in the regulation of tumor necrosis factor-induced gene activation and cell death.

FEBS J 2016 07 24;283(14):2626-39. Epub 2016 Jan 24.

Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, London, UK.

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http://dx.doi.org/10.1111/febs.13644DOI Listing
July 2016

Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling.

Trends Cell Biol 2016 06 11;26(6):445-461. Epub 2016 Feb 11.

Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, London WC1E 6BT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.tcb.2016.01.006DOI Listing
June 2016

Poly-ubiquitination in TNFR1-mediated necroptosis.

Cell Mol Life Sci 2016 06 11;73(11-12):2165-76. Epub 2016 Apr 11.

Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, London, UK.

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http://link.springer.com/content/pdf/10.1007%2Fs00018-016-21
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http://link.springer.com/10.1007/s00018-016-2191-4
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http://dx.doi.org/10.1007/s00018-016-2191-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4887548PMC
June 2016

NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions.

Immunity 2016 Mar;44(3):553-567

Institute for Genetics, University of Cologne, 50674 Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, 50931 Cologne, Germany; Center for Molecular Medicine (CMMC), University of Cologne, 50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4803910PMC
March 2016

The Schistosoma mansoni T2 ribonuclease omega-1 modulates inflammasome-dependent IL-1β secretion in macrophages.

Int J Parasitol 2015 Nov 16;45(13):809-13. Epub 2015 Sep 16.

Department of Pathology, University of Cambridge, Tennis Court Road, CB2 1QP Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ijpara.2015.08.005DOI Listing
November 2015

Linear ubiquitination in immunity.

Immunol Rev 2015 Jul;266(1):190-207

Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, London, UK.

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http://dx.doi.org/10.1111/imr.12309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737190PMC
July 2015

WHO grade related expression of TRAIL-receptors and apoptosis regulators in meningioma.

Pathol Res Pract 2015 Feb 13;211(2):109-16. Epub 2014 Nov 13.

Translational Centre for Regenerative Medicine (TRM) Leipzig and Faculty of Medicine, University of Leipzig, Leipzig, Germany.

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http://dx.doi.org/10.1016/j.prp.2014.11.002DOI Listing
February 2015

Bortezomib sensitizes primary meningioma cells to TRAIL-induced apoptosis by enhancing formation of the death-inducing signaling complex.

J Neuropathol Exp Neurol 2014 Nov;73(11):1034-46

From the Department of Gastroenterology, Heidelberg University Hospital (RK, TMG); German Cancer Research Center, Division of Signaling and Functional Genomics (CB); Department of Cell and Molecular Biology, Faculty of Medicine Mannheim, Heidelberg University (CB); and HI-STEM gGmbH/German Cancer Research Center Heidelberg (MRS), Heidelberg, Germany; National Cancer Institute Regina Elena (TLH), Rome, Italy; Translational Centre for Regenerative Medicine Leipzig and Faculty of Medicine (HH, L-XX) and Departments of Neurosurgery (L-XX, WK, JM) and Neuropathology (WCM, MB), University of Leipzig, Leipzig, Germany; Ames Laboratory-US DOE, and Department of Physics and Astronomy, Iowa State University, Ames, Iowa (TK); Departments of Cardiology (MK) and Pathology (PS), University Hospital Heidelberg, Heidelberg, Germany; and Centre for Cell Death, Cancer and Inflammation, UCL Cancer Institute, London, United Kingdom (HW).

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http://dx.doi.org/10.1097/NEN.0000000000000129DOI Listing
November 2014

HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death.

Cell Rep 2014 Oct 2;9(1):153-165. Epub 2014 Oct 2.

Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, 72 Huntley Street, London WC1E 6DD, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.08.066DOI Listing
October 2014

Hepatocyte expression of TRAIL pathway regulators correlates with histopathological and clinical parameters in chronic HCV infection.

Pathol Res Pract 2014 Feb 7;210(2):83-91. Epub 2013 Nov 7.

Department of Gastroenterology, University Hospital Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.prp.2013.10.005DOI Listing
February 2014

Regulated necrosis: the expanding network of non-apoptotic cell death pathways.

Nat Rev Mol Cell Biol 2014 Feb;15(2):135-47

Molecular Signaling and Cell Death Unit, Inflammation Research Center, Flanders Institute for Biotechnology (VIB), Ghent University, 9052 Ghent, Belgium.

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http://dx.doi.org/10.1038/nrm3737DOI Listing
February 2014

Ubiquitin in the immune system.

EMBO Rep 2014 Jan 27;15(1):28-45. Epub 2013 Dec 27.

Centre for Cell Death, Cancer, and Inflammation (CCCI) UCL Cancer Institute, University College London, London, UK.

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http://dx.doi.org/10.1002/embr.201338025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303447PMC
January 2014

Two independent pathways of regulated necrosis mediate ischemia-reperfusion injury.

Proc Natl Acad Sci U S A 2013 Jul 1;110(29):12024-9. Epub 2013 Jul 1.

Division of Nephrology and Hypertension and Institute for Pathology, Christian-Albrechts-University, 24105 Kiel, Germany.

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http://dx.doi.org/10.1073/pnas.1305538110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718149PMC
July 2013

Death receptor-ligand systems in cancer, cell death, and inflammation.

Authors:
Henning Walczak

Cold Spring Harb Perspect Biol 2013 May 1;5(5):a008698. Epub 2013 May 1.

Centre for Cell Death, Cancer, and Inflammation (CCCI), UCL Cancer Institute, University College London, London WC1E 6BT, United Kingdom.

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http://dx.doi.org/10.1101/cshperspect.a008698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3632055PMC
May 2013

Linear ubiquitination: a newly discovered regulator of cell signalling.

Trends Biochem Sci 2013 Feb 17;38(2):94-102. Epub 2013 Jan 17.

Centre for Cell Death, Cancer, and Inflammation, UCL Cancer Institute, University College London, London, UK.

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http://www.cell.com/trends/biochemical-sciences/pdf/S0968-00
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http://dx.doi.org/10.1016/j.tibs.2012.11.007DOI Listing
February 2013

Apoptosis therapy: driving cancers down the road to ruin.

Nat Med 2013 Feb;19(2):131-3

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http://dx.doi.org/10.1038/nm.3076DOI Listing
February 2013

Generation and physiological roles of linear ubiquitin chains.

BMC Biol 2012 Mar 15;10:23. Epub 2012 Mar 15.

Tumour Immunology Unit, Department of Medicine, Imperial College London, 10N5 Commonwealth Building, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1186/1741-7007-10-23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3305636PMC
March 2012

No one can whistle a symphony alone - how different ubiquitin linkages cooperate to orchestrate NF-κB activity.

J Cell Sci 2012 Feb;125(Pt 3):549-59

Tumour Immunology Unit, Division of Immunology and Inflammation, Department of Medicine, Imperial College London, 10th floor, Commonwealth Building, Du Cane Road, London W12 0NN, UK.

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http://dx.doi.org/10.1242/jcs.091793DOI Listing
February 2012

The emerging role of linear ubiquitination in cell signaling.

Sci Signal 2011 Dec 20;4(204):re5. Epub 2011 Dec 20.

Tumour Immunology Unit, Department of Medicine, Imperial College London, London W12 0NN, UK.

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http://dx.doi.org/10.1126/scisignal.2002187DOI Listing
December 2011

TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer.

Authors:
Henning Walczak

Immunol Rev 2011 Nov;244(1):9-28

Tumour Immunology Unit, Division of Immunology and Inflammation, Department of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1111/j.1600-065X.2011.01066.xDOI Listing
November 2011

Hypochlorite-modified low-density lipoprotein induces the apoptotic machinery in Jurkat T-cell lines.

Biochem Biophys Res Commun 2011 Jul 17;410(4):895-900. Epub 2011 Jun 17.

Institute of Molecular Biology and Biochemistry, Center for Molecular Medicine, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.1016/j.bbrc.2011.06.089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3144388PMC
July 2011

Caspase-8 and bid: caught in the act between death receptors and mitochondria.

Biochim Biophys Acta 2011 Apr 2;1813(4):558-63. Epub 2011 Feb 2.

Tumour Immunology Unit, Division of Immunology and inflammation, Department of Medicine, Imperial College London, Hammersmith Hospital Campus, Commonwealth Building Du Care Road, London, UK.

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http://dx.doi.org/10.1016/j.bbamcr.2011.01.026DOI Listing
April 2011

Tyrosine phosphatase inhibition triggers sustained canonical serine-dependent NFkappaB activation via Src-dependent blockade of PP2A.

Biochem Pharmacol 2010 Aug 5;80(4):439-47. Epub 2010 May 5.

Institute of Cell Biology and Immunology, University of Stuttgart, Germany.

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http://dx.doi.org/10.1016/j.bcp.2010.04.028DOI Listing
August 2010

TRAIL and other TRAIL receptor agonists as novel cancer therapeutics.

Adv Exp Med Biol 2009 ;647:195-206

Department of Immunology Division of Medicine, Imperial College London, London, UK.

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http://dx.doi.org/10.1007/978-0-387-89520-8_14DOI Listing
June 2010

Bortezomib sensitizes primary human esthesioneuroblastoma cells to TRAIL-induced apoptosis.

J Neurooncol 2010 Apr 20;97(2):171-85. Epub 2009 Sep 20.

Department of Internal Medicine, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11060-009-0010-6DOI Listing
April 2010

From biochemical principles of apoptosis induction by TRAIL to application in tumour therapy.

Results Probl Cell Differ 2009 ;49:115-43

Tumour Immunology Unit, Division of Medicine, Imperial College, London, W12 0NN, UK.

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http://dx.doi.org/10.1007/400_2008_27DOI Listing
March 2010

Differential expression of the TRAIL/TRAIL-receptor system in patients with inflammatory bowel disease.

Pathol Res Pract 2010 Jan 1;206(1):43-50. Epub 2009 Dec 1.

Department of Gastroenterology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.prp.2009.09.005DOI Listing
January 2010

Prognostic significance of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor expression in patients with breast cancer.

J Mol Med (Berl) 2009 Oct 13;87(10):995-1007. Epub 2009 Aug 13.

Division of Apoptosis Regulation (D040), German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00109-009-0510-zDOI Listing
October 2009

Micro-nanostructured protein arrays: a tool for geometrically controlled ligand presentation.

Small 2009 May;5(9):1014-8

Abteilung Neue Materialien und Biosysteme, Max-Planck-Institut für Metallforschung & Institut für Biophysikalische Chemie, Universität Heidelberg, Stuttgart, Germany.

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http://dx.doi.org/10.1002/smll.200801219DOI Listing
May 2009

Is TRAIL the holy grail of cancer therapy?

Apoptosis 2009 Apr;14(4):607-23

Department of Immunology, Tumour Immunology Unit, Imperial College London, Hammersmith Campus, London, UK.

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http://dx.doi.org/10.1007/s10495-009-0321-2DOI Listing
April 2009

Death receptors as targets for anti-cancer therapy.

J Cell Mol Med 2008 Dec;12(6B):2566-85

Tumour Immunology Unit, Division of Medicine, Imperial College London, United Kingdom.

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http://dx.doi.org/10.1111/j.1582-4934.2008.00514.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828874PMC
December 2008

NF-kappaB inhibition reveals differential mechanisms of TNF versus TRAIL-induced apoptosis upstream or at the level of caspase-8 activation independent of cIAP2.

J Invest Dermatol 2008 May 8;128(5):1134-47. Epub 2007 Nov 8.

Laboratory for Experimental Dermatology, Department of Dermatology and Venerology, Otto-von-Guericke-University Magdeburg, Magdeburg, Germany.

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http://dx.doi.org/10.1038/sj.jid.5701141DOI Listing
May 2008

Biochemical analysis of the native TRAIL death-inducing signaling complex.

Methods Mol Biol 2008 ;414:221-39

Division of Apoptosis Regulation, German Cancer Research Center, Im Neuenheimer Feld, Heidelberg, Germany.

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http://dx.doi.org/10.1007/978-1-59745-339-4_16DOI Listing
February 2008

TRAIL signalling: decisions between life and death.

Int J Biochem Cell Biol 2007 14;39(7-8):1462-75. Epub 2007 Feb 14.

Division of Apoptosis Regulation (D040), Tumor Immunology Program, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, 69120 Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.biocel.2007.02.007DOI Listing
October 2007

The promise of TRAIL--potential and risks of a novel anticancer therapy.

J Mol Med (Berl) 2007 Sep 17;85(9):923-35. Epub 2007 Apr 17.

Division of Apoptosis Regulation, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00109-007-0194-1DOI Listing
September 2007

Lidocaine induces apoptosis via the mitochondrial pathway independently of death receptor signaling.

Anesthesiology 2007 Jul;107(1):136-43

Department of Anesthesiology, University of Düsseldorf, Düsseldorf, Germany.

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http://dx.doi.org/10.1097/01.anes.0000268389.39436.66DOI Listing
July 2007

TRAIL: a multifunctional cytokine.

Front Biosci 2007 May 1;12:3813-24. Epub 2007 May 1.

Tumor Immunology Program, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 580, D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.2741/2354DOI Listing
May 2007

TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window.

Hepatology 2007 Mar;45(3):649-58

Division of Apoptosis Regulation, German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/hep.21555DOI Listing
March 2007

Protective effect of Mangifera indica L. polyphenols on human T lymphocytes against activation-induced cell death.

Pharmacol Res 2007 Feb 19;55(2):167-73. Epub 2006 Nov 19.

Department of Biomedical Research, Center of Pharmaceutical Chemistry, P.O. Box 16042, Havana, Cuba.

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http://dx.doi.org/10.1016/j.phrs.2006.11.004DOI Listing
February 2007

TRAIL enhances efficacy of radiotherapy in a p53 mutant, Bcl-2 overexpressing lymphoid malignancy.

Radiother Oncol 2006 Aug 17;80(2):214-22. Epub 2006 Aug 17.

Division of Immunology, The Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

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http://linkinghub.elsevier.com/retrieve/pii/S016781400600308
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http://dx.doi.org/10.1016/j.radonc.2006.07.030DOI Listing
August 2006