Publications by authors named "Henne Holstege"

45Publications

Immune response and endocytosis pathways are associated with the resilience against Alzheimer's disease.

Transl Psychiatry 2020 Sep 29;10(1):332. Epub 2020 Sep 29.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41398-020-01018-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7524800PMC
September 2020

What determines cognitive functioning in the oldest-old? The EMIF-AD 90+ Study.

J Gerontol B Psychol Sci Soc Sci 2020 Sep 8. Epub 2020 Sep 8.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/geronb/gbaa152DOI Listing
September 2020

The Role of Age-Related Clonal Hematopoiesis in Genetic Sequencing Studies.

Am J Hum Genet 2020 09;107(3):575-576

Pattern Recognition & Bioinformatics, Delft University of Technology, Delft 2628CD, the Netherlands; Leiden Computational Biology Center, Leiden University Medical Center, Leiden 2300RC, the Netherlands; Section of Molecular Epidemiology, Leiden University Medical Center, Leiden 2300RC, the Netherlands.

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http://dx.doi.org/10.1016/j.ajhg.2020.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7477003PMC
September 2020

Broad phenotype of cysteine-altering variants in UK Biobank: CADASIL to nonpenetrance.

Neurology 2020 Sep 30;95(13):e1835-e1843. Epub 2020 Jul 30.

From the Center for Hereditary Small Vessel Disease, Department of Clinical Genetics (J.W.R., R.J.H., G.G., J.G.D., S.A.J.L.O.), Department of Human Genetics (M.O.), Department of Biomedical Data Sciences (E.B.v.d.A.), and Department of Biomedical Data Sciences (E.S.), Leiden University Medical Center, the Netherlands; Institute for Stroke and Dementia Research (M.D., M.D., R.M.), University Hospital, LMU Munich, Germany; Pattern Recognition & Bioinformatics (E.B.v.d.A., H.H.), Delft University of Technology; Alzheimer Center Amsterdam (H.H.), Department of Neurology, Amsterdam Neuroscience, and Department of Clinical Genetics (H.H.), Vrije Universiteit Amsterdam, Amsterdam UMC, the Netherlands; and Department of Radiology and Imaging Sciences (K.N., A.S.), Indiana Alzheimer Disease Center, Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis.

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http://dx.doi.org/10.1212/WNL.0000000000010525DOI Listing
September 2020

Genetic Liability for Depression, Social Factors and Their Interaction Effect in Depressive Symptoms and Depression Over Time in Older Adults.

Am J Geriatr Psychiatry 2020 08 8;28(8):844-855. Epub 2020 Mar 8.

Amsterdam UMC- Vrije Universiteit Amsterdam, Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, (NS, NMS, MH) Amsterdam, the Netherlands; Department of Sociology, Vrije Universiteit, (BS, MH) Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.jagp.2020.02.011DOI Listing
August 2020

CHOP: haplotype-aware path indexing in population graphs.

Genome Biol 2020 03 11;21(1):65. Epub 2020 Mar 11.

Delft Bioinformatics Lab, Delft University of Technology, Van Mourik Broekmanweg 6, Delft, 2628 XE, The Netherlands.

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http://dx.doi.org/10.1186/s13059-020-01963-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066762PMC
March 2020

Longitudinal Maintenance of Cognitive Health in Centenarians in the 100-plus Study.

JAMA Netw Open 2020 02 5;3(2):e200094. Epub 2020 Feb 5.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1001/jamanetworkopen.2020.0094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137688PMC
February 2020

Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2020 05;139(5):959-962

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-019-02107-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7181435PMC
May 2020

Self-reported oral health in the Dutch 100-plus Study of cognitively healthy centenarians: an observational cohort study.

BMC Geriatr 2019 12 18;19(1):355. Epub 2019 Dec 18.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, PO Box 7057, Amsterdam, 1007 MB, The Netherlands.

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http://dx.doi.org/10.1186/s12877-019-1358-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6921395PMC
December 2019

A meta-analysis of genome-wide association studies identifies multiple longevity genes.

Nat Commun 2019 08 14;10(1):3669. Epub 2019 Aug 14.

NHLBI's and Boston University's Framingham Heart Study, Framingham, MA, 01702, USA.

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http://dx.doi.org/10.1038/s41467-019-11558-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6694136PMC
August 2019

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.

Authors:
Sven J van der Lee Olivia J Conway Iris Jansen Minerva M Carrasquillo Luca Kleineidam Erik van den Akker Isabel Hernández Kristel R van Eijk Najada Stringa Jason A Chen Anna Zettergren Till F M Andlauer Monica Diez-Fairen Javier Simon-Sanchez Alberto Lleó Henrik Zetterberg Marianne Nygaard Cornelis Blauwendraat Jeanne E Savage Jonas Mengel-From Sonia Moreno-Grau Michael Wagner Juan Fortea Michael J Keogh Kaj Blennow Ingmar Skoog Manuel A Friese Olga Pletnikova Miren Zulaica Carmen Lage Itziar de Rojas Steffi Riedel-Heller Ignacio Illán-Gala Wei Wei Bernard Jeune Adelina Orellana Florian Then Bergh Xue Wang Marc Hulsman Nina Beker Niccolo Tesi Christopher M Morris Begoña Indakoetxea Lyduine E Collij Martin Scherer Estrella Morenas-Rodríguez James W Ironside Bart N M van Berckel Daniel Alcolea Heinz Wiendl Samantha L Strickland Pau Pastor Eloy Rodríguez Rodríguez Bradley F Boeve Ronald C Petersen Tanis J Ferman Jay A van Gerpen Marcel J T Reinders Ryan J Uitti Lluís Tárraga Wolfgang Maier Oriol Dols-Icardo Amit Kawalia Maria Carolina Dalmasso Mercè Boada Uwe K Zettl Natasja M van Schoor Marian Beekman Mariet Allen Eliezer Masliah Adolfo López de Munain Alexander Pantelyat Zbigniew K Wszolek Owen A Ross Dennis W Dickson Neill R Graff-Radford David Knopman Rosa Rademakers Afina W Lemstra Yolande A L Pijnenburg Philip Scheltens Thomas Gasser Patrick F Chinnery Bernhard Hemmer Martijn A Huisman Juan Troncoso Fermin Moreno Ellen A Nohr Thorkild I A Sørensen Peter Heutink Pascual Sánchez-Juan Danielle Posthuma Jordi Clarimón Kaare Christensen Nilüfer Ertekin-Taner Sonja W Scholz Alfredo Ramirez Agustín Ruiz Eline Slagboom Wiesje M van der Flier Henne Holstege

Acta Neuropathol 2019 08 27;138(2):237-250. Epub 2019 May 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00401-019-02026-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6660501PMC
August 2019

Neuropsychological Test Performance of Cognitively Healthy Centenarians: Normative Data From the Dutch 100-Plus Study.

J Am Geriatr Soc 2019 04 27;67(4):759-767. Epub 2018 Dec 27.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/jgs.15729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379661PMC
April 2019

The 100-plus Study of cognitively healthy centenarians: rationale, design and cohort description.

Eur J Epidemiol 2018 Dec 25;33(12):1229-1249. Epub 2018 Oct 25.

Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, de Boelelaan 1118, 1081 HZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s10654-018-0451-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290855PMC
December 2018

EIF2AK3 variants in Dutch patients with Alzheimer's disease.

Neurobiol Aging 2019 01 24;73:229.e11-229.e18. Epub 2018 Aug 24.

Alzheimer Center and Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands; Alzheimer Center, Department of Neurology, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.08.016DOI Listing
January 2019

Neuropathology and cognitive performance in self-reported cognitively healthy centenarians.

Acta Neuropathol Commun 2018 07 23;6(1):64. Epub 2018 Jul 23.

Alzheimer Centre, Department of Neurology, Amsterdam Neuroscience, VU University Medical Center, Postbus 7057, 1007 MB, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/s40478-018-0558-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6055341PMC
July 2018

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

Neurobiol Aging 2017 01 2;49:214.e13-214.e15. Epub 2016 Sep 2.

Department of Molecular Neuroscience, UCL Institute of Neurology, London, UK; Department of Medical Sciences and Institute of Biomedicine-iBiMED, University of Aveiro, Aveiro, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2016.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154872PMC
January 2017

A novel CCM2 variant in a family with non-progressive cognitive complaints and cerebral microbleeds.

Am J Med Genet B Neuropsychiatr Genet 2017 Apr 8;174(3):220-226. Epub 2016 Jun 8.

Alzheimer Center, Department of Neurology, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/ajmg.b.32468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363380PMC
April 2017

Influence of genetic variants in SORL1 gene on the manifestation of Alzheimer's disease.

Neurobiol Aging 2015 Mar 11;36(3):1605.e13-20. Epub 2014 Dec 11.

Alzheimer Center and Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1016/j.neurobiolaging.2014.12.007DOI Listing
March 2015

WISECONDOR: detection of fetal aberrations from shallow sequencing maternal plasma based on a within-sample comparison scheme.

Nucleic Acids Res 2014 Mar 28;42(5):e31. Epub 2013 Oct 28.

Delft Bioinformatics Lab, Delft University of Technology, Mekelweg 4, 2628 CD Delft, The Netherlands, Department of Clinical Genetics, VU University Medical Center Amsterdam, van der Boechorststraat 7 (BS7/J377), 1081 BT Amsterdam, The Netherlands and Department of Clinical Chemistry, VU University Medical Center Amsterdam, van der Boechorststraat 7 (BS7/J377), 1081 BT Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/nar/gkt992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950725PMC
March 2014

BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations.

BMC Cancer 2010 Nov 30;10:654. Epub 2010 Nov 30.

Division of Molecular Biology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/1471-2407-10-654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002929PMC
November 2010

KC-SMARTR: An R package for detection of statistically significant aberrations in multi-experiment aCGH data.

BMC Res Notes 2010 Nov 11;3:298. Epub 2010 Nov 11.

Department of Bioinformatics and Statistics, The Netherlands Cancer Institute, Plesmanlaan 121, 1066CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1186/1756-0500-3-298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995794PMC
November 2010

BRD7 is a candidate tumour suppressor gene required for p53 function.

Nat Cell Biol 2010 Apr 14;12(4):380-9. Epub 2010 Mar 14.

The Netherlands Cancer Institute, Division of Gene Regulation, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands.

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http://www.nature.com/articles/ncb2038
Publisher Site
http://dx.doi.org/10.1038/ncb2038DOI Listing
April 2010

High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.

Cancer Res 2009 Apr 31;69(8):3625-33. Epub 2009 Mar 31.

Division of Molecular Biology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3426DOI Listing
April 2009

Human and mouse oligonucleotide-based array CGH.

Nucleic Acids Res 2005 Dec 16;33(22):e192. Epub 2005 Dec 16.

Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/nar/gni191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1316119PMC
December 2005

Activation of central melanocortin pathways by fenfluramine.

Science 2002 Jul;297(5581):609-11

Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.

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http://www.sciencemag.org/cgi/doi/10.1126/science.1072327
Publisher Site
http://dx.doi.org/10.1126/science.1072327DOI Listing
July 2002