Publications by authors named "Heng-Jia Liu"

13Publications

PtdIns(3,4,5)P-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis.

Proc Natl Acad Sci U S A 2020 11 23;117(45):28056-28067. Epub 2020 Oct 23.

Cancer Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, VIC 3800, Australia;

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November 2020

MITF is a driver oncogene and potential therapeutic target in kidney angiomyolipoma tumors through transcriptional regulation of CYR61.

Oncogene 2021 Jan 20;40(1):112-126. Epub 2020 Oct 20.

Cancer Genetics Laboratory, Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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January 2021

Immunotherapy for Lymphangioleiomyomatosis and Tuberous Sclerosis: Progress and Future Directions.

Chest 2019 12 19;156(6):1062-1067. Epub 2019 Aug 19.

Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA. Electronic address:

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December 2019

Rapamycin-upregulated miR-29b promotes mTORC1-hyperactive cell growth in TSC2-deficient cells by downregulating tumor suppressor retinoic acid receptor β (RARβ).

Oncogene 2019 12 16;38(49):7367-7383. Epub 2019 Aug 16.

Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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December 2019

Vitamin D binding protein: a new biomarker of disease severity in lymphangioleiomyomatosis.

Eur Respir J 2018 11 1;52(5). Epub 2018 Nov 1.

Division of Pulmonary and Critical Care Medicine, Dept of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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November 2018

TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy.

JCI Insight 2018 04 19;3(8). Epub 2018 Apr 19.

Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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April 2018

TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β.

Hum Mol Genet 2018 05;27(9):1654-1663

Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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May 2018

The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells.

J Biol Chem 2015 Aug 24;290(34):20827-40. Epub 2015 Jun 24.

From the Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Monash University, Clayton, Victoria 3800, Australia, the Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria 3800, Australia, and

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August 2015

INPP4A/INPP4B and P-Rex proteins: related but different?

Adv Biol Regul 2012 Jan;52(1):265-79

Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

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January 2012