Hendrik Harms

Hendrik Harms

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Hendrik Harms

Hendrik Harms

Publications by authors named "Hendrik Harms"

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First-Pass Techniques Applied to Standard Dynamic Cardiac PET: A reappraisal of Old Invasive Techniques to Assess Cardiac Function.

Semin Nucl Med 2020 Jul 18;50(4):349-356. Epub 2020 Mar 18.

Clinical Institute, Aarhus University, Aarhus, Denmark; Dept. of Surgical Sciences, Nuclear Medicine and PET, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1053/j.semnuclmed.2020.02.002DOI Listing
July 2020

Diagnostic Accuracy of [C]PIB Positron Emission Tomography for Detection of Cardiac Amyloidosis.

JACC Cardiovasc Imaging 2020 Jun 13;13(6):1337-1347. Epub 2020 May 13.

Department of Nuclear Medicine and PET, Aarhus University Hospital, Aarhus, Denmark; Department of Surgical Sciences, Radiology, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.jcmg.2020.02.023DOI Listing
June 2020

Increased Myocardial Oxygen Consumption Precedes Contractile Dysfunction in Hypertrophic Cardiomyopathy Caused by Pathogenic Gene Variants.

J Am Heart Assoc 2020 Apr 15;9(8):e015316. Epub 2020 Apr 15.

Department of Physiology Amsterdam University Medical Center Amsterdam Cardiovascular Sciences Vrije Universiteit University Medical Center Amsterdam Amsterdam the Netherlands.

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http://dx.doi.org/10.1161/JAHA.119.015316DOI Listing
April 2020

Value of CMR and PET in Predicting Ventricular Arrhythmias in Ischemic Cardiomyopathy Patients Eligible for ICD.

JACC Cardiovasc Imaging 2020 Apr 15. Epub 2020 Apr 15.

Department of Cardiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, Amsterdam, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jcmg.2020.01.026DOI Listing
April 2020

Coronary Microvascular Dysfunction, Left Ventricular Remodeling, and Clinical Outcomes in Patients With Chronic Kidney Impairment.

Circulation 2020 01 29;141(1):21-33. Epub 2019 Nov 29.

Cardiovascular Imaging Program, Departments of Radiology and Medicine; Division of Nuclear Medicine and Molecular Imaging, Department of Radiology; and Divisions of Cardiovascular Medicine and Nephrology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (N.S.B., A.S., W.Z., A.G., K.F., C.B., H.J.H., P.B., E.A., S.D., C.F.B., J.H., H.S., V.T., M.S., S.D., R.B., R.C.D., S.D.S., M.F.D.C.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.043916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117866PMC
January 2020

Myocardial Efficiency: A Fundamental Physiological Concept on the Verge of Clinical Impact.

JACC Cardiovasc Imaging 2019 Dec 18. Epub 2019 Dec 18.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden; Department of Clinical Physiology, Akademiska University Hospital, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jcmg.2019.08.030DOI Listing
December 2019

Quantitative estimation of extravascular lung water volume and preload by dynamic 15O-water positron emission tomography.

Eur Heart J Cardiovasc Imaging 2019 Oct;20(10):1120-1128

Department of Nuclear Medicine & PET Centre, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, Aarhus DK, Denmark.

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http://dx.doi.org/10.1093/ehjci/jez038DOI Listing
October 2019

The relationship between tumor aggressiveness and cholinergic PET imaging in prostate cancer tissue. A proof-of-concept study.

Am J Nucl Med Mol Imaging 2019 15;9(3):185-192. Epub 2019 Jun 15.

Department of Nuclear Medicine and PET, Aarhus University Hospital Aarhus, Denmark.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627478PMC
June 2019

Automatic calculation of myocardial external efficiency using a single C-acetate PET scan.

J Nucl Cardiol 2018 12 26;25(6):1937-1944. Epub 2018 Jun 26.

Department of Nuclear Medicine, & PET Center, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N, Denmark.

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http://dx.doi.org/10.1007/s12350-018-1338-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280778PMC
December 2018

Non-invasive quantification of tumor blood flow in prostate cancer using O-HO PET/CT.

Am J Nucl Med Mol Imaging 2018 20;8(5):292-302. Epub 2018 Oct 20.

Department of Nuclear Medicine and PET Centre, Aarhus University Hospital Aarhus C, Denmark.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261877PMC
October 2018

Quantitative myocardial blood flow imaging with integrated time-of-flight PET-MR.

EJNMMI Phys 2017 Dec 6;4(1). Epub 2017 Jan 6.

Nuclear Medicine & PET, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1186/s40658-016-0171-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216001PMC
December 2017

Calculation of left ventricular volumes and ejection fraction from dynamic cardiac-gated O-water PET/CT: 5D-PET.

EJNMMI Phys 2017 Nov 14;4(1):26. Epub 2017 Nov 14.

Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, SE-751 85, Uppsala, Sweden.

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http://dx.doi.org/10.1186/s40658-017-0195-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686036PMC
November 2017

Metoprolol Reduces Hemodynamic and Metabolic Overload in Asymptomatic Aortic Valve Stenosis Patients: A Randomized Trial.

Circ Cardiovasc Imaging 2017 10;10(10)

From the Department of Cardiology (N.H.H., W.Y.K., R.N., S.H.P., H.W.) and Department of Nuclear Medicine and PET-Center (J.S., H.J.H., L.P.T., J.F., K.B.), Aarhus University Hospital, Denmark; Department of Cardiology, Horsens Regional Hospital, Denmark (K.K.D.); and Aarhus Hjerteklinik, Denmark (I.S.).

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http://dx.doi.org/10.1161/CIRCIMAGING.117.006557DOI Listing
October 2017

Disease Stage-Dependent Changes in Cardiac Contractile Performance and Oxygen Utilization Underlie Reduced Myocardial Efficiency in Human Inherited Hypertrophic Cardiomyopathy.

Circ Cardiovasc Imaging 2017 May;10(5)

From the Department of Cardiology (A.G., P.K., R.Y.P., A.C.v.R., T.G.), Department of Physiology (A.G., R.Y.P., J.v.d.V.), Department of Radiology and Nuclear Medicine, Institute for Cardiovascular Research (ICaR-VU) (H.J.H., A.A.L.), VU University Medical Center, Amsterdam, The Netherlands; Department of Cardiology, Erasmus Medical Center Rotterdam, The Netherlands (M.M.); Department of Cardiology, Medical Center Alkmaar, The Netherlands (T.G.); and ICIN-The Netherlands Heart Institute, Utrecht (A.G., J.v.d.V.).

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http://dx.doi.org/10.1161/CIRCIMAGING.116.005604DOI Listing
May 2017

Myocardial denervation coincides with scar heterogeneity in ischemic cardiomyopathy: A PET and CMR study.

J Nucl Cardiol 2016 12 9;23(6):1480-1488. Epub 2015 Nov 9.

Department of Cardiology and Institute for Cardiovascular Research (ICaR-VU), VU University Medical Center, De Boelelaan 1118, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s12350-015-0316-zDOI Listing
December 2016

Automatic Extraction of Myocardial Mass and Volume Using Parametric Images from Dynamic Nongated PET.

J Nucl Med 2016 09 28;57(9):1382-7. Epub 2016 Apr 28.

Department of Nuclear Medicine and PET Centre, Aarhus University Hospital, Aarhus, Denmark Department of Nuclear Medicine and PET, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.2967/jnumed.115.170613DOI Listing
September 2016

Noninvasive Quantification of Myocardial 11C-Meta-Hydroxyephedrine Kinetics.

J Nucl Med 2016 Sep 26;57(9):1376-81. Epub 2016 May 26.

Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.2967/jnumed.115.167437DOI Listing
September 2016

Bisoprolol in idiopathic pulmonary arterial hypertension: an explorative study.

Eur Respir J 2016 09 7;48(3):787-96. Epub 2016 Jul 7.

Dept of pulmonary medicine, Institute for cardiovascular research, VU University medical center, Amsterdam, The Netherlands Dept of physiology, Institute for cardiovascular research, VU University medical center, Amsterdam, The Netherlands

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http://dx.doi.org/10.1183/13993003.00090-2016DOI Listing
September 2016

Evaluation of ECG-gated [(11)C]acetate PET for measuring left ventricular volumes, mass, and myocardial external efficiency.

J Nucl Cardiol 2016 08 19;23(4):670-9. Epub 2016 Apr 19.

Department of Nuclear Medicine & PET-Centre, Aarhus University Hospital, Aarhus C, Denmark.

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http://dx.doi.org/10.1007/s12350-015-0331-0DOI Listing
August 2016

Non-invasive imaging to identify susceptibility for ventricular arrhythmias in ischaemic left ventricular dysfunction.

Heart 2016 06 3;102(11):832-40. Epub 2016 Feb 3.

Department of Cardiology, Institute for Cardiovascular Research (ICaR-VU), VU University Medical Center, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1136/heartjnl-2015-308467DOI Listing
June 2016

Intrathecal immunoglobulin A and G antibodies to synapsin in a patient with limbic encephalitis.

Neurol Neuroimmunol Neuroinflamm 2015 Dec 4;2(6):e169. Epub 2015 Nov 4.

Department of Neurology (J.P., K.R.) and Institute for Integrative Neuroanatomy (M.H., J.-F.Z., G.A.-H.), Charité-Universitätsmedizin Berlin; St. Josefs-Krankenhaus Potsdam (C.O., H.H.), Germany; the Department of Neuroscience and Brain Technologies (A.S., F.C., F.B.), Istituto Italiano di Tecnologia, Genova, Italy; the Department of Physiology and Cell Biology (D.G.), Faculty of Health Sciences and Zlotowski Center for Neuroscience, Ben-Gurion University of the Negev, Beer-Sheva, Israel; and the Institute of Toxicology (A.P.), Hannover Medical School, Germany.

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http://dx.doi.org/10.1212/NXI.0000000000000169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635552PMC
December 2015

Use of a Single 11C-Meta-Hydroxyephedrine Scan for Assessing Flow-Innervation Mismatches in Patients with Ischemic Cardiomyopathy.

J Nucl Med 2015 Nov 30;56(11):1706-11. Epub 2015 Jul 30.

Department of Radiology and Nuclear Medicine, VU University Medical Center, Amsterdam, Netherlands.

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http://dx.doi.org/10.2967/jnumed.115.154377DOI Listing
November 2015

Myocardial efficiency is an important determinant of functional improvement after aortic valve replacement in aortic valve stenosis patients: a combined PET and CMR study.

Eur Heart J Cardiovasc Imaging 2015 Aug 13;16(8):882-9. Epub 2015 Feb 13.

ICIN-The Netherlands Heart Institute, Utrecht, The Netherlands Department of Physiology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1093/ehjci/jev009DOI Listing
August 2015

Sympathetic denervation is associated with microvascular dysfunction in non-infarcted myocardium in patients with cardiomyopathy.

Eur Heart J Cardiovasc Imaging 2015 Jul 21;16(7):788-98. Epub 2015 Feb 21.

Department of Cardiology, VU University Medical Center, De Boelelaan 1117, PO Box 7057, Amsterdam, HV 1081, The Netherlands Institute for Cardiovascular Research (ICaR-VU), VU University Medical Center, Amsterdam, The Netherlands

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http://dx.doi.org/10.1093/ehjci/jev013DOI Listing
July 2015

Effective treatment with intravenous immunoglobulins reduces autoreactive T-cell response in patients with CIDP.

J Neurol Neurosurg Psychiatry 2015 Jun 29;86(6):686-91. Epub 2014 Jul 29.

Department of Neurology, St. Josefs Krankenhaus Potsdam, Potsdam, Germany.

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http://dx.doi.org/10.1136/jnnp-2014-307708DOI Listing
June 2015

Quantification of [(11)C]-meta-hydroxyephedrine uptake in human myocardium.

EJNMMI Res 2014 Dec 26;4(1):52. Epub 2014 Sep 26.

Department of Radiology and Nuclear Medicine, VU University Medical Center, P.O. Box 7057, 1007 MB, Amsterdam, the Netherlands,

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http://dx.doi.org/10.1186/s13550-014-0052-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452641PMC
December 2014

Impact of anatomical and functional severity of coronary atherosclerotic plaques on the transmural perfusion gradient: a [15O]H2O PET study.

Eur Heart J 2014 Aug 29;35(31):2094-105. Epub 2014 Apr 29.

Department of Cardiology, VU University Medical Center, Amsterdam, De Boelelaan 1117, 1081 HV, The Netherlands

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http://dx.doi.org/10.1093/eurheartj/ehu170DOI Listing
August 2014

Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations.

Cardiovasc Res 2014 Jul 16;103(2):248-57. Epub 2014 May 16.

Department of Physiology, Institute for Cardiovascular Research (ICaR-VU), VU University Medical Center, Amsterdam, The Netherlands ICIN Netherlands Heart Institute, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvu127DOI Listing
July 2014

Comparison of clinical non-commercial tools for automated quantification of myocardial blood flow using oxygen-15-labelled water PET/CT.

Eur Heart J Cardiovasc Imaging 2014 Apr 9;15(4):431-41. Epub 2013 Oct 9.

Department of Nuclear Medicine and PET Research, VU University Medical Centre, De Boelelaan 1117, Amsterdam 1081 HV, The Netherlands.

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http://dx.doi.org/10.1093/ehjci/jet177DOI Listing
April 2014

Effect of cardiac hybrid ¹⁵O-water PET/CT imaging on downstream referral for invasive coronary angiography and revascularization rate.

Eur Heart J Cardiovasc Imaging 2014 Feb 9;15(2):170-9. Epub 2013 Jul 9.

Department of Cardiology, VU University Medical Center, De Boelelaan 1117, Amsterdam 1081 HV, The Netherlands.

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http://dx.doi.org/10.1093/ehjci/jet125DOI Listing
February 2014

Effect of type 2 diabetes mellitus on epicardial adipose tissue volume and coronary vasomotor function.

Am J Cardiol 2014 Jan 3;113(1):90-7. Epub 2013 Oct 3.

Department of Cardiology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.amjcard.2013.09.022DOI Listing
January 2014

Impaired hyperemic myocardial blood flow is associated with inducibility of ventricular arrhythmia in ischemic cardiomyopathy.

Circ Cardiovasc Imaging 2014 Jan 16;7(1):20-30. Epub 2013 Dec 16.

Department of Cardiology and Institute for Cardiovascular Research, Departments of Radiology and Nuclear Medicine, Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.

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https://www.ahajournals.org/doi/10.1161/CIRCIMAGING.113.0011
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http://dx.doi.org/10.1161/CIRCIMAGING.113.001158DOI Listing
January 2014

Pulmonary vascular remodeling and right heart failure in pulmonary hypertension: future role of positron emission tomography in decoding the enigma.

Transl Respir Med 2013 Dec 11;1(1):16. Epub 2013 Dec 11.

Department of Pulmonary Medicine, VU University Medical Center, PO Box 7057, Amsterdam, MB, 1007, The Netherlands.

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http://dx.doi.org/10.1186/2213-0802-1-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715170PMC
December 2013

STRoke Adverse outcome is associated WIth NoSocomial Infections (STRAWINSKI): procalcitonin ultrasensitive-guided antibacterial therapy in severe ischaemic stroke patients - rationale and protocol for a randomized controlled trial.

Int J Stroke 2013 Oct 28;8(7):598-603. Epub 2012 Aug 28.

Neurocure Clinical Research Center, Charité - Universitätsmedizin Berlin, Berlin, Germany; Department of Neurology and Center for Stroke Research Berlin, Charité -Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1111/j.1747-4949.2012.00858.xDOI Listing
October 2013

Decision-making in the diagnosis and treatment of stroke-associated pneumonia.

J Neurol Neurosurg Psychiatry 2012 Dec 28;83(12):1225-30. Epub 2012 Sep 28.

NeuroCure Clinical Reseach Center (NCRC), Center for Stroke Research Berlin (CSB), Department of Neurology, Charité-Universitaetsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.

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http://dx.doi.org/10.1136/jnnp-2012-302194DOI Listing
December 2012

Predicting post-stroke infections and outcome with blood-based immune and stress markers.

Cerebrovasc Dis 2012 15;33(6):580-8. Epub 2012 Jun 15.

Neurocure Clinical Research Center, Department of Neurology and Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1159/000338080DOI Listing
November 2012

Development of a clinical score (A2DS2) to predict pneumonia in acute ischemic stroke.

Stroke 2012 Oct 12;43(10):2617-23. Epub 2012 Jul 12.

Centre for Stroke Research Berlin, Charite-Universitätsmedizin, Berlin, Germany.

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http://dx.doi.org/10.1161/STROKEAHA.112.653055DOI Listing
October 2012

Impact of infections on long-term outcome after severe middle cerebral artery infarction.

J Neurol Sci 2012 Aug 8;319(1-2):15-7. Epub 2012 Jun 8.

NeuroCure Clinical Research Center, Charité - Universitätsmedizin Berlin, Charitéplatz 1, 10117 Berlin, Germany.

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http://dx.doi.org/10.1016/j.jns.2012.05.042DOI Listing
August 2012

Influence of stroke localization on autonomic activation, immunodepression, and post-stroke infection.

Cerebrovasc Dis 2011 18;32(6):552-60. Epub 2011 Nov 18.

Neurological Department and Center of Stroke Research Berlin (CSB), Charité Universitätsmedizin Berlin, Charitéplatz 1, Berlin, Germany.

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http://dx.doi.org/10.1159/000331922DOI Listing
April 2012

Automatic generation of absolute myocardial blood flow images using [15O]H2O and a clinical PET/CT scanner.

Eur J Nucl Med Mol Imaging 2011 May 27;38(5):930-9. Epub 2011 Jan 27.

Department of Nuclear Medicine & PET Research, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00259-011-1730-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070081PMC
May 2011

Parametric images of myocardial viability using a single 15O-H2O PET/CT scan.

J Nucl Med 2011 May 15;52(5):745-9. Epub 2011 Apr 15.

Department of Nuclear Medicine and PET Research, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.2967/jnumed.110.085431DOI Listing
May 2011

Coronary steal: revealing the diagnosis with quantitative cardiac PET/CT.

J Nucl Cardiol 2010 Dec;17(6):1118-21

Department of Nuclear Medicine and PET Research, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s12350-010-9265-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990011PMC
December 2010

Quantitative parametric perfusion images using 15O-labeled water and a clinical PET/CT scanner: test-retest variability in lung cancer.

J Nucl Med 2010 Nov 18;51(11):1684-90. Epub 2010 Oct 18.

Department of Nuclear Medicine and PET Research, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.2967/jnumed.110.079137DOI Listing
November 2010

Low-dose quantitative myocardial blood flow imaging using 15O-water and PET without attenuation correction.

J Nucl Med 2010 Apr 17;51(4):575-80. Epub 2010 Mar 17.

Department of Nuclear Medicine and PET Research, VU University Medical Centre, Amsterdam, The Netherlands.

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http://dx.doi.org/10.2967/jnumed.109.070748DOI Listing
April 2010