Hemmo A Drexhage

Hemmo A Drexhage

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Hemmo A Drexhage

Hemmo A Drexhage

Publications by authors named "Hemmo A Drexhage"

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97Publications

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Effects of Air Pollution on Lung Innate Lymphoid Cells: Review of In Vitro and In Vivo Experimental Studies.

Int J Environ Res Public Health 2019 07 2;16(13). Epub 2019 Jul 2.

Department of Immunology, Erasmus Medical Center, 3015GD Rotterdam, The Netherlands.

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http://dx.doi.org/10.3390/ijerph16132347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650824PMC
July 2019

Inflammatory cytokines and growth factors were not associated with psychosis liability or childhood trauma.

PLoS One 2019 5;14(7):e0219139. Epub 2019 Jul 5.

Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219139PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6611659PMC
July 2019

Editorial: Activation and de-activation of inflammatory pathways. The disequilibrium of immune-neuro-endocrine networks in psychiatric disorders.

Authors:
Hemmo A Drexhage

Brain Behav Immun 2019 May 22;78:5-6. Epub 2019 Jan 22.

Dept of Immunology, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2019.01.007DOI Listing
May 2019

Higher Baseline Proinflammatory Cytokines Mark Poor Antidepressant Response in Bipolar Disorder.

J Clin Psychiatry 2017 Sep/Oct;78(8):e986-e993

Department of Immunology, Erasmus University Medical Centre, Rotterdam, Netherlands.

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http://dx.doi.org/10.4088/JCP.16m11310DOI Listing
November 2017

Th17 cells correlate positively to the structural and functional integrity of the brain in bipolar depression and healthy controls.

Brain Behav Immun 2017 Mar 23;61:317-325. Epub 2016 Dec 23.

Department of Immunology, Erasmus University Medical Centre, Rotterdam, Netherlands.

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http://dx.doi.org/10.1016/j.bbi.2016.12.020DOI Listing
March 2017

Blood-based immune-endocrine biomarkers of treatment response in depression.

J Psychiatr Res 2016 12 31;83:249-259. Epub 2016 Aug 31.

Department of Chemical Engineering and Biotechnology, University of Cambridge, Cambridge, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychires.2016.08.020DOI Listing
December 2016

The dysregulated brain: consequences of spatial and temporal brain complexity for bipolar disorder pathophysiology and diagnosis.

Bipolar Disord 2016 12 20;18(8):696-701. Epub 2016 Dec 20.

Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1111/bdi.12454DOI Listing
December 2016

Diffusion tensor imaging in euthymic bipolar disorder - A tract-based spatial statistics study.

J Affect Disord 2016 Oct 1;203:281-291. Epub 2016 Jun 1.

University of Groningen, Neuroimaging Center, Groningen, The Netherlands; Institute du Cerveau et de la Moelle épinière, Paris, France.

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http://dx.doi.org/10.1016/j.jad.2016.05.040DOI Listing
October 2016

The Immune Pathogenesis of Type 1 Diabetes: Not Only Thinking Outside the Cell but Also Outside the Islet and Out of the Box.

Diabetes 2016 08;65(8):2130-3

Department of Immunology, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.2337/dbi16-0030DOI Listing
August 2016

Tryptophan pathway alterations in the postpartum period and in acute postpartum psychosis and depression.

J Affect Disord 2016 Jan 22;189:298-305. Epub 2015 Oct 22.

Department of Psychiatry, Erasmus Medical Centre, 's Gravendijkwal 230, Rotterdam, The Netherlands; National Center for Register-Based Research, Aarhus School of Business and Social Sciences Aarhus University, Fuglesangs Allé 4, Aarhus, Denmark.

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http://dx.doi.org/10.1016/j.jad.2015.09.064DOI Listing
January 2016

S100B Serum Levels Predict Treatment Response in Patients with Melancholic Depression.

Int J Neuropsychopharmacol 2015 Sep 12;19(3):pyv103. Epub 2015 Sep 12.

Department of Psychiatry, University of Münster, Germany (Dr Ambrée, Ms Grosse, Dr Alferink, Dr Rothermundt, and Dr Arolt); Department of Psychiatry, Erasmus Medical Center Rotterdam, The Netherlands (Drs Bergink and Birkenhäger); Radiology Morphological Solutions, Rotterdam, The Netherlands (Ms Grosse); Department of Immunology, Erasmus Medical Center Rotterdam, The Netherlands (Dr Drexhage); Cluster of Excellence EXC 1003, Cells in Motion, Münster, Germany (Dr Alferink); Department of Psychiatry, St. Rochus-Hospital, Telgte, Oberhausen, Germany (Dr Rothermundt).

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http://dx.doi.org/10.1093/ijnp/pyv103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815471PMC
September 2015

Monocyte activation, brain-derived neurotrophic factor (BDNF), and S100B in bipolar offspring: a follow-up study from adolescence into adulthood.

Bipolar Disord 2015 Feb 17;17(1):39-49. Epub 2014 Jul 17.

Brain Center Rudolf Magnus, Department of Psychiatry, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/bdi.12231DOI Listing
February 2015

Feature-expression heat maps--a new visual method to explore complex associations between two variable sets.

J Biomed Inform 2015 Feb 14;53:156-61. Epub 2014 Oct 14.

University of Groningen, University Medical Center Groningen, Department of Psychiatry, Groningen, The Netherlands; University of Groningen, University Medical Center Groningen, Department of General Practice, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jbi.2014.10.003DOI Listing
February 2015

Neuroinflammation in bipolar disorder - A [(11)C]-(R)-PK11195 positron emission tomography study.

Brain Behav Immun 2014 Aug 3;40:219-25. Epub 2014 Apr 3.

University of Groningen, University Medical Center Groningen, Department of Nuclear Medicine and Molecular Imaging, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.bbi.2014.03.016DOI Listing
August 2014

Autoimmunity, inflammation, and psychosis: a search for peripheral markers.

Biol Psychiatry 2014 Feb 19;75(4):324-31. Epub 2013 Oct 19.

Department of Immunology, Erasmus University Medical Centre, Rotterdam, Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S00063223130094
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http://dx.doi.org/10.1016/j.biopsych.2013.09.037DOI Listing
February 2014

Immune system and glucose metabolism interaction in schizophrenia: a chicken-egg dilemma.

Prog Neuropsychopharmacol Biol Psychiatry 2014 Jan 17;48:287-94. Epub 2012 Oct 17.

Department of Psychiatry, University of Magdeburg, Magdeburg, Germany; Center for Behavioral Brain Sciences, Magdeburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.pnpbp.2012.09.016DOI Listing
January 2014

Evidence for a dysregulated immune system in the etiology of psychiatric disorders.

J Neuroimmune Pharmacol 2013 Sep 5;8(4):900-20. Epub 2013 May 5.

Department of Immunology, Na1101, Erasmus MC, Dr. Molewaterplein 50, Erasmus MC, 3015 GE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11481-013-9462-8DOI Listing
September 2013

Immune system dysregulation in first-onset postpartum psychosis.

Biol Psychiatry 2013 May 25;73(10):1000-7. Epub 2012 Dec 25.

Department of Psychiatry, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.biopsych.2012.11.006DOI Listing
May 2013

Down-regulation of inflammation-protective microRNAs 146a and 212 in monocytes of patients with postpartum psychosis.

Brain Behav Immun 2013 Mar 4;29:147-55. Epub 2013 Jan 4.

Department of Immunology, Erasmus Medical Centre Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bbi.2012.12.018DOI Listing
March 2013

Increased level of serum cytokines, chemokines and adipokines in patients with schizophrenia is associated with disease and metabolic syndrome.

Psychoneuroendocrinology 2012 Dec 27;37(12):1901-11. Epub 2012 Apr 27.

Department of Immunology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.psyneuen.2012.04.001DOI Listing
December 2012

Reduced numbers of dendritic cells with a tolerogenic phenotype in the prediabetic pancreas of NOD mice.

J Leukoc Biol 2012 Dec 25;92(6):1207-13. Epub 2012 Sep 25.

Department of Immunology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1189/jlb.0312168DOI Listing
December 2012

Thymosin α 1: a novel therapeutic option for patients with refractory chronic purulent rhinosinusitis.

Ann N Y Acad Sci 2012 Oct;1270:1-7

Department of Immunology, Erasmus Medical Center, Rotterdam, the Netherlands.

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http://dx.doi.org/10.1111/j.1749-6632.2012.06742.xDOI Listing
October 2012

Immune and neuroimmune alterations in mood disorders and schizophrenia.

Int Rev Neurobiol 2011 ;101:169-201

Department of Immunology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/B978-0-12-387718-5.00007-9DOI Listing
August 2012

Abnormalities of dendritic cell precursors in the pancreas of the NOD mouse model of diabetes.

Eur J Immunol 2012 Jan 28;42(1):186-94. Epub 2011 Nov 28.

Department of Immunology, Erasmus MC University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1002/eji.201141770DOI Listing
January 2012

The activation of monocyte and T cell networks in patients with bipolar disorder.

Brain Behav Immun 2011 Aug 8;25(6):1206-13. Epub 2011 Apr 8.

Dept. of Immunology, ErasmusMC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.bbi.2011.03.013DOI Listing
August 2011

Whole orbital tissue culture identifies imatinib mesylate and adalimumab as potential therapeutics for Graves' ophthalmopathy.

Br J Ophthalmol 2011 May 10;95(5):735-8. Epub 2011 Feb 10.

Department of Immunology, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1136/bjo.2010.192302DOI Listing
May 2011

Prevalence of autoimmune thyroid dysfunction in postpartum psychosis.

Br J Psychiatry 2011 Apr 22;198(4):264-8. Epub 2011 Feb 22.

Department of Psychiatry, Erasmus University Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1192/bjp.bp.110.082990DOI Listing
April 2011

An inflammatory gene-expression fingerprint in monocytes of autoimmune thyroid disease patients.

J Clin Endocrinol Metab 2010 Apr 10;95(4):1962-71. Epub 2010 Feb 10.

Department of Immunology, Erasmus Medical Center, 3015 CE Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2009-1455DOI Listing
April 2010

Platelet-derived growth factor-BB: a stimulus for cytokine production by orbital fibroblasts in Graves' ophthalmopathy.

Invest Ophthalmol Vis Sci 2010 Feb 24;51(2):1002-7. Epub 2009 Sep 24.

Department of Immunology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1167/iovs.09-4338DOI Listing
February 2010

The mononuclear phagocyte system and its cytokine inflammatory networks in schizophrenia and bipolar disorder.

Expert Rev Neurother 2010 Jan;10(1):59-76

Department of Immunology, Erasmus MC, PO Box 2040, 3000CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1586/ern.09.144DOI Listing
January 2010

Plasmacytoid dendritic cells in autoimmune diabetes - potential tools for immunotherapy.

Immunobiology 2009 22;214(9-10):791-9. Epub 2009 Jul 22.

Department of Immunology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.imbio.2009.06.002DOI Listing
December 2009

Altered fractalkine cleavage potentially promotes local inflammation in NOD salivary gland.

Arthritis Res Ther 2008 19;10(3):R69. Epub 2008 Jun 19.

Department of Immunology, Erasmus MC, P,O, Box 2040, 3000 CA Rotterdam, The Netherlands.

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http://dx.doi.org/10.1186/ar2441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2483461PMC
December 2008

Chorionic gonadotropin up-regulates long pentraxin 3 expression in myeloid cells.

J Leukoc Biol 2008 Nov 6;84(5):1346-52. Epub 2008 Aug 6.

Department of Immunology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1189/jlb.0108067DOI Listing
November 2008

Lack of CCR5 on dendritic cells promotes a proinflammatory environment in submandibular glands of the NOD mouse.

J Leukoc Biol 2008 May 19;83(5):1194-200. Epub 2008 Feb 19.

Department of Immunology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1189/jlb.1107794DOI Listing
May 2008

Expression of GAD67 and novel GAD67 splice variants during human fetal pancreas development: GAD67 expression in the fetal pancreas.

Endocr Pathol 2007 ;18(1):31-6

Department of Pathology, Josephine Nefkens Institute, Room 222, Erasmus MC-University Medical Centre Rotterdam, P.O. Box 2040, Dr. Molenwaterplein 50, 3000 CA Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2782109PMC
September 2007

Is autoimmune thyroiditis part of the genetic vulnerability (or an endophenotype) for bipolar disorder?

Biol Psychiatry 2007 Jul 4;62(2):135-40. Epub 2006 Dec 4.

Reinier van Arkel group, 's-Hertogenbosch, Department of Psychiatry, University Medical Centre Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.biopsych.2006.08.041DOI Listing
July 2007

Signs of a higher prevalence of autoimmune thyroiditis in female offspring of bipolar parents.

Eur Neuropsychopharmacol 2007 May-Jun;17(6-7):394-9. Epub 2006 Nov 29.

University Medical Centre Utrecht/Department of Child and Adolescent Psychiatry, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.euroneuro.2006.10.005DOI Listing
June 2007

A relative resistance of T cells to dexamethasone in bipolar disorder.

Bipolar Disord 2006 Dec;8(6):740-50

Department of Immunology, Erasmus MC, 3000 DR Rotterdam, the Netherlands.

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http://dx.doi.org/10.1111/j.1399-5618.2006.00359.xDOI Listing
December 2006

Thyroid hormones, dementia, and atrophy of the medial temporal lobe.

J Clin Endocrinol Metab 2006 Jul 24;91(7):2569-73. Epub 2006 Apr 24.

Department of Epidemiology and Biostatistics, Erasmus Medical Center, 3000 DR Rotterdam, The Netherlands.

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http://dx.doi.org/10.1210/jc.2006-0449DOI Listing
July 2006

Monocyte-derived dendritic cells in bipolar disorder.

Biol Psychiatry 2006 Feb 13;59(4):317-26. Epub 2005 Sep 13.

Department of Immunology, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.biopsych.2005.06.041DOI Listing
February 2006

Diabetes-prone NOD mice show an expanded subpopulation of mature circulating monocytes, which preferentially develop into macrophage-like cells in vitro.

J Leukoc Biol 2005 Jul 23;78(1):70-9. Epub 2005 Mar 23.

Department of Immunology, Erasmus MC, Rotterdam, The Netherlands.

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http://doi.wiley.com/10.1189/jlb.1104662
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http://dx.doi.org/10.1189/jlb.1104662DOI Listing
July 2005

Immunomagnetic selection of functional dendritic cells from human lymph nodes.

Immunol Lett 2005 Jul 27;99(2):162-8. Epub 2005 Mar 27.

Department of Gastroenterology and Hepatology, Room L-455, Erasmus Medical Center, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.imlet.2005.02.013DOI Listing
July 2005

Bone marrow precursors of nonobese diabetic mice develop into defective macrophage-like dendritic cells in vitro.

J Immunol 2004 Oct;173(7):4342-51

Department of Immunology, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.4049/jimmunol.173.7.4342DOI Listing
October 2004

A high prevalence of organ-specific autoimmunity in patients with bipolar disorder.

Biol Psychiatry 2004 Oct;56(7):476-82

Department of Immunology, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.biopsych.2004.07.003DOI Listing
October 2004

Immune cells, pancreas development, regeneration and type 1 diabetes.

Trends Immunol 2004 May;25(5):222-9

CNRS UMR 7059, Université Paris 7/Denis Diderot, 2 place Jussieu, 75251 Paris Cedex 05, France.

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http://dx.doi.org/10.1016/j.it.2004.02.012DOI Listing
May 2004

The association between autoimmune thyroiditis, autoimmune gastritis and type 1 diabetes.

Pediatr Endocrinol Rev 2003 Sep;1(1):22-37

Dept. of Immunology, Erasmus MC, Rotterdam, The Netherlands.

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September 2003

High numbers of circulating activated T cells and raised levels of serum IL-2 receptor in bipolar disorder.

Biol Psychiatry 2003 Jan;53(2):157-65

Department of Immunology, Erasmus University Rotterdam (MNB, HAD), Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/s0006-3223(02)01452-xDOI Listing
January 2003

Islet abnormalities in the pathogenesis of autoimmune diabetes.

Trends Endocrinol Metab 2002 Jul;13(5):209-14

Dept Immunology, Erasmus MC, University Medical Center, PO Box 1738, 3000 DR Rotterdam, The Netherlands.

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July 2002

High rate of autoimmune thyroiditis in bipolar disorder: lack of association with lithium exposure.

Biol Psychiatry 2002 Feb;51(4):305-11

Altrecht Centre for Mental Health Care and University Medical Centre Utrecht, Vrouwjuttenhof 18, 3512 PZ Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/s0006-3223(01)01217-3DOI Listing
February 2002