Hemali Phatnani

Hemali Phatnani

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Hemali Phatnani

Hemali Phatnani

Publications by authors named "Hemali Phatnani"

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27Publications

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Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons.

Genome Biol 2018 08 15;19(1):117. Epub 2018 Aug 15.

Laboratory of Molecular Neuro-Oncology, The Rockefeller University, 1230 York Ave., New York, NY, 10065, USA.

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http://dx.doi.org/10.1186/s13059-018-1493-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6092797PMC
August 2018

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene.

Authors:
Aude Nicolas Kevin P Kenna Alan E Renton Nicola Ticozzi Faraz Faghri Ruth Chia Janice A Dominov Brendan J Kenna Mike A Nalls Pamela Keagle Alberto M Rivera Wouter van Rheenen Natalie A Murphy Joke J F A van Vugt Joshua T Geiger Rick A Van der Spek Hannah A Pliner Shankaracharya Bradley N Smith Giuseppe Marangi Simon D Topp Yevgeniya Abramzon Athina Soragia Gkazi John D Eicher Aoife Kenna Gabriele Mora Andrea Calvo Letizia Mazzini Nilo Riva Jessica Mandrioli Claudia Caponnetto Stefania Battistini Paolo Volanti Vincenzo La Bella Francesca L Conforti Giuseppe Borghero Sonia Messina Isabella L Simone Francesca Trojsi Fabrizio Salvi Francesco O Logullo Sandra D'Alfonso Lucia Corrado Margherita Capasso Luigi Ferrucci Cristiane de Araujo Martins Moreno Sitharthan Kamalakaran David B Goldstein Aaron D Gitler Tim Harris Richard M Myers Hemali Phatnani Rajeeva Lochan Musunuri Uday Shankar Evani Avinash Abhyankar Michael C Zody Julia Kaye Steven Finkbeiner Stacia K Wyman Alex LeNail Leandro Lima Ernest Fraenkel Clive N Svendsen Leslie M Thompson Jennifer E Van Eyk James D Berry Timothy M Miller Stephen J Kolb Merit Cudkowicz Emily Baxi Michael Benatar J Paul Taylor Evadnie Rampersaud Gang Wu Joanne Wuu Giuseppe Lauria Federico Verde Isabella Fogh Cinzia Tiloca Giacomo P Comi Gianni Sorarù Cristina Cereda Philippe Corcia Hannu Laaksovirta Liisa Myllykangas Lilja Jansson Miko Valori John Ealing Hisham Hamdalla Sara Rollinson Stuart Pickering-Brown Richard W Orrell Katie C Sidle Andrea Malaspina John Hardy Andrew B Singleton Janel O Johnson Sampath Arepalli Peter C Sapp Diane McKenna-Yasek Meraida Polak Seneshaw Asress Safa Al-Sarraj Andrew King Claire Troakes Caroline Vance Jacqueline de Belleroche Frank Baas Anneloor L M A Ten Asbroek José Luis Muñoz-Blanco Dena G Hernandez Jinhui Ding J Raphael Gibbs Sonja W Scholz Mary Kay Floeter Roy H Campbell Francesco Landi Robert Bowser Stefan M Pulst John M Ravits Daniel J L MacGowan Janine Kirby Erik P Pioro Roger Pamphlett James Broach Glenn Gerhard Travis L Dunckley Christopher B Brady Neil W Kowall Juan C Troncoso Isabelle Le Ber Kevin Mouzat Serge Lumbroso Terry D Heiman-Patterson Freya Kamel Ludo Van Den Bosch Robert H Baloh Tim M Strom Thomas Meitinger Aleksey Shatunov Kristel R Van Eijk Mamede de Carvalho Maarten Kooyman Bas Middelkoop Matthieu Moisse Russell L McLaughlin Michael A Van Es Markus Weber Kevin B Boylan Marka Van Blitterswijk Rosa Rademakers Karen E Morrison A Nazli Basak Jesús S Mora Vivian E Drory Pamela J Shaw Martin R Turner Kevin Talbot Orla Hardiman Kelly L Williams Jennifer A Fifita Garth A Nicholson Ian P Blair Guy A Rouleau Jesús Esteban-Pérez Alberto García-Redondo Ammar Al-Chalabi Ekaterina Rogaeva Lorne Zinman Lyle W Ostrow Nicholas J Maragakis Jeffrey D Rothstein Zachary Simmons Johnathan Cooper-Knock Alexis Brice Stephen A Goutman Eva L Feldman Summer B Gibson Franco Taroni Antonia Ratti Cinzia Gellera Philip Van Damme Wim Robberecht Pietro Fratta Mario Sabatelli Christian Lunetta Albert C Ludolph Peter M Andersen Jochen H Weishaupt William Camu John Q Trojanowski Vivianna M Van Deerlin Robert H Brown Leonard H van den Berg Jan H Veldink Matthew B Harms Jonathan D Glass David J Stone Pentti Tienari Vincenzo Silani Adriano Chiò Christopher E Shaw Bryan J Traynor John E Landers

Neuron 2018 03;97(6):1268-1283.e6

Department of Neurology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuron.2018.02.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5867896PMC
March 2018

Evaluating Synthetic Activation and Repression of Neuropsychiatric-Related Genes in hiPSC-Derived NPCs, Neurons, and Astrocytes.

Stem Cell Reports 2017 08 27;9(2):615-628. Epub 2017 Jul 27.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550013PMC
August 2017

An Efficient Platform for Astrocyte Differentiation from Human Induced Pluripotent Stem Cells.

Stem Cell Reports 2017 08 27;9(2):600-614. Epub 2017 Jul 27.

Department of Neuroscience & Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, USA; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, 1425 Madison Avenue, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5550034PMC
August 2017

Astrocytes in neurodegenerative disease.

Cold Spring Harb Perspect Biol 2015 Apr 15;7(6). Epub 2015 Apr 15.

Columbia University Medical Center, Department of Biochemistry and Molecular Biophysics, New York, New York 10032.

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http://dx.doi.org/10.1101/cshperspect.a020628DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448607PMC
April 2015

An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex.

J Neurosci 2014 Sep;34(36):11929-47

The Vivian L. Smith Department of Neurosurgery, University of Texas Medical School at Houston, Houston, Texas 77057, Center for Stem Cell and Regenerative Medicine, University of Texas Brown Institute of Molecular Medicine, Houston, Texas 77057,

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http://dx.doi.org/10.1523/JNEUROSCI.1860-14.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4152602PMC
September 2014

Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy.

Proc Natl Acad Sci U S A 2013 Mar 11;110(12):4697-702. Epub 2013 Feb 11.

Euan MacDonald Centre for Motor Neurone Disease Research, Centre for Neuroregeneration, and Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1300398110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607024PMC
March 2013

Intricate interplay between astrocytes and motor neurons in ALS.

Proc Natl Acad Sci U S A 2013 Feb 6;110(8):E756-65. Epub 2013 Feb 6.

Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center, New York, NY 10032, USA.

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http://dx.doi.org/10.1073/pnas.1222361110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581928PMC
February 2013

Proteomic analysis of mitotic RNA polymerase II reveals novel interactors and association with proteins dysfunctional in disease.

Mol Cell Proteomics 2012 Jun 22;11(6):M111.011767. Epub 2011 Dec 22.

MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, London W12 0NN, United Kingdom.

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http://dx.doi.org/10.1074/mcp.M111.011767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3433901PMC
June 2012

Stochastic expression of the interferon-β gene.

PLoS Biol 2012 Jan 24;10(1):e1001249. Epub 2012 Jan 24.

Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.1001249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3265471PMC
January 2012

The phosphoCTD-interacting domain of Topoisomerase I.

Biochem Biophys Res Commun 2010 Jun 20;397(1):117-9. Epub 2010 May 20.

Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.bbrc.2010.05.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2900466PMC
June 2010

Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.

Proc Natl Acad Sci U S A 2009 Dec 20;106(49):20960-5. Epub 2009 Nov 20.

Program in Cellular and Molecular Medicine, Immune Disease Institute, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0911405106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791631PMC
December 2009

NMR assignment of the SRI domain of human Set2/HYPB.

J Biomol NMR 2006 ;36 Suppl 1

Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1007/s10858-005-4690-8DOI Listing
August 2007

Phosphorylation and functions of the RNA polymerase II CTD.

Genes Dev 2006 Nov;20(21):2922-36

Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1101/gad.1477006DOI Listing
November 2006

Solution structure of the Set2-Rpb1 interacting domain of human Set2 and its interaction with the hyperphosphorylated C-terminal domain of Rpb1.

Proc Natl Acad Sci U S A 2005 Dec 28;102(49):17636-41. Epub 2005 Nov 28.

Department of Biochemistry, Duke University Medical Center, Research Drive, Durham, NC 27710, USA.

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http://dx.doi.org/10.1073/pnas.0506350102DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1308900PMC
December 2005

A novel domain in Set2 mediates RNA polymerase II interaction and couples histone H3 K36 methylation with transcript elongation.

Mol Cell Biol 2005 Apr;25(8):3305-16

Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, 405 Mary Ellen Jones, Chapel Hill, NC 27599-7260, USA.

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http://dx.doi.org/10.1128/MCB.25.8.3305-3316.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1069628PMC
April 2005

Expanding the functional repertoire of CTD kinase I and RNA polymerase II: novel phosphoCTD-associating proteins in the yeast proteome.

Biochemistry 2004 Dec;43(50):15702-19

Department of Biochemistry, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://pubs.acs.org/doi/abs/10.1021/bi048364h
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http://dx.doi.org/10.1021/bi048364hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2879061PMC
December 2004

C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats.

J Biol Chem 2004 Jun 26;279(24):24957-64. Epub 2004 Mar 26.

Department of Biochemistry, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1074/jbc.M402218200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680323PMC
June 2004

Identifying phosphoCTD-associating proteins.

Methods Mol Biol 2004 ;257:17-28

Biochemistry Department, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1385/1-59259-750-5:017DOI Listing
April 2004