Publications by authors named "Helmut Butzkueven"

100Publications

Immunoregulatory effects and therapeutic potential of vitamin D in multiple sclerosis.

Br J Pharmacol 2020 Sep 5;177(18):4113-4133. Epub 2020 Aug 5.

Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/bph.15201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443468PMC
September 2020

Prediction of on-treatment disability worsening in RRMS with the MAGNIMS score.

Mult Scler 2020 Jul 8:1352458520936823. Epub 2020 Jul 8.

CORe, Department of Medicine, The Royal Melbourne Hospital, The University of Melbourne, Melbourne, VIC, Australia/ Melbourne MS Centre, Department of Neurology, The Royal Melbourne Hospital, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1177/1352458520936823DOI Listing
July 2020

MSCOVID19: Using social media to achieve rapid dissemination of health information.

Mult Scler Relat Disord 2020 Jun 24;45:102338. Epub 2020 Jun 24.

Alfred Health, Clinical Neurosciences, Melbourne, Australia; Department of Neuroscience, Central Clinical School, Monash University, Melbourne Australia.

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http://dx.doi.org/10.1016/j.msard.2020.102338DOI Listing
June 2020

Real-world effectiveness of cladribine for Australian patients with multiple sclerosis: An MSBase registry substudy.

Mult Scler 2020 Jun 12:1352458520921087. Epub 2020 Jun 12.

CORe, Department of Medicine, University of Melbourne, Melbourne, VIC, Australia/Department of Neurology, Royal Melbourne Hospital, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1177/1352458520921087DOI Listing
June 2020

The MSReactor computerized cognitive battery correlates with the processing speed test in relapsing-remitting multiple sclerosis.

Mult Scler Relat Disord 2020 Aug 25;43:102212. Epub 2020 May 25.

Department of Neurology, MSNI Service, Alfred Health, Melbourne, Australia; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Australia; Department of Neurology, Royal Prince Alfred Hospital, Sydney, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2020.102212DOI Listing
August 2020

Seizures in autoimmune encephalitis: Kindling the fire.

Epilepsia 2020 Jun 13;61(6):1033-1044. Epub 2020 May 13.

Department of Neurosciences, Central Clinical School, Faculty of Medicine, Nursing, and Health Sciences, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/epi.16515DOI Listing
June 2020

OnabotulinumtoxinA treatment for MS-tremor modifies fMRI tremor response in central sensory-motor integration areas.

Mult Scler Relat Disord 2020 May 5;40:101984. Epub 2020 Feb 5.

Department of Neurology, Royal Melbourne Hospital, Australia; The Bionics Institute, Australia; Department of Neuroscience, Central Clinical School, Monash University, Australia.

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http://dx.doi.org/10.1016/j.msard.2020.101984DOI Listing
May 2020

Head-to-head drug comparisons in multiple sclerosis: Urgent action needed.

Neurology 2019 10 7;93(18):793-809. Epub 2019 Oct 7.

From the Department of Neuroinflammation (C.T.), Queen Square Multiple Sclerosis Centre, UCL Institute of Neurology, University College London, UK; Neurology/Neuroimmunology Department (C.T., M.T., X.M.), Multiple Sclerosis Centre of Catalonia, Vall d'Hebron University Hospital, Barcelona, Spain; Department of Medicine (T.K.), CORe, University of Melbourne, Australia; Department of Neurology (T.K.), Royal Melbourne Hospital, Australia; Division of Neurology (J.O., X.M.), University of Toronto, St Michael's Hospital, Canada; Department of Health Sciences (DISSAL) (M.P.S.), University of Genoa, Italy; and Central Clinical School (H.B.), Alfred Centre, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000008319DOI Listing
October 2019

Innate Immunity in the Central Nervous System: A Missing Piece of the Autoimmune Encephalitis Puzzle?

Front Immunol 2019 10;10:2066. Epub 2019 Sep 10.

Department of Neurosciences, Faculty of Medicine, Nursing and Health Sciences, Central Clinical School, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.3389/fimmu.2019.02066DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6746826PMC
September 2019

Early imaging predictors of longer term multiple sclerosis risk and severity in acute optic neuritis.

Mult Scler J Exp Transl Clin 2019 Jul-Sep;5(3):2055217319863122. Epub 2019 Jul 23.

Department of Neuroscience, Central Clinical School, Monash University, Australia.

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http://dx.doi.org/10.1177/2055217319863122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651676PMC
July 2019

The feasibility, reliability and concurrent validity of the MSReactor computerized cognitive screening tool in multiple sclerosis.

Ther Adv Neurol Disord 2019 12;12:1756286419859183. Epub 2019 Jul 12.

Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1177/1756286419859183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628542PMC
July 2019

The MSBase registry: Informing clinical practice.

Mult Scler 2019 12 23;25(14):1828-1834. Epub 2019 May 23.

Central Clinical School, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1177/1352458519848965DOI Listing
December 2019

The role of vitamin D and P2X7R in multiple sclerosis.

J Neuroimmunol 2019 05 14;330:159-169. Epub 2019 Mar 14.

Department of Physiology, The University of Melbourne, Melbourne, Australia; Department of Neuroscience, Monash University, Melbourne, Australia; Department of Neurology, Melbourne Health, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jneuroim.2019.03.004DOI Listing
May 2019

Functional neuroplasticity in response to cerebello-thalamic injury underpins the clinical presentation of tremor in multiple sclerosis.

Mult Scler 2020 05 25;26(6):696-705. Epub 2019 Mar 25.

Department of Medicine and Radiology, University of Melbourne, Parkville, VIC, Australia/Florey Institute of Neuroscience and Mental Health, Parkville, VIC, Australia.

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http://dx.doi.org/10.1177/1352458519837706DOI Listing
May 2020

Prognosis in autoimmune encephalitis: Database.

Data Brief 2018 Dec 13;21:2694-2703. Epub 2018 Nov 13.

Department of Neuroscience, Monash University, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.dib.2018.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6290378PMC
December 2018

Prognosticating autoimmune encephalitis: A systematic review.

J Autoimmun 2019 01 26;96:24-34. Epub 2018 Oct 26.

Department of Neuroscience, Monash University, Melbourne, Australia; Department of Neurology, Melbourne Health, Melbourne, Australia; Department of Neurology, Alfred Health, Melbourne, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S08968411183048
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http://dx.doi.org/10.1016/j.jaut.2018.10.014DOI Listing
January 2019

Evaluation of pregnancy outcomes in patients with multiple sclerosis after fingolimod exposure.

Ther Adv Neurol Disord 2018 3;11:1756286418804760. Epub 2018 Nov 3.

Department of Neurology, St Josef Hospital, Ruhr University, Bochum, Germany.

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http://dx.doi.org/10.1177/1756286418804760DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6236588PMC
November 2018

Obesity and brain volume loss in multiple sclerosis.

Neurology 2018 12 14;91(24):1079-1080. Epub 2018 Nov 14.

From the Departments of Internal Medicine and Community Health Sciences (R.A.M.), Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada; Central Clinical School (H.B.), Alfred Centre, Monash University, Melbourne, Australia; Departments of Epidemiology and Nutrition (A.A.), Harvard T.H. Chan School of Public Health; and Channing Laboratory (A.A.), Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1212/WNL.0000000000006638DOI Listing
December 2018

What speech can tell us: A systematic review of dysarthria characteristics in Multiple Sclerosis.

Autoimmun Rev 2018 Dec 11;17(12):1202-1209. Epub 2018 Oct 11.

Centre for Neuroscience of Speech, University of Melbourne, Australia; The Bionics Institute, East Melbourne, Australia; Department of Neurology, Royal Melbourne Hospital, Melbourne Australia; Department of Neurodegeneration, Hertie Institute for Clinical Brain Research, University of Tübingen, Germany; Redenlab, Melbourne, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15689972183023
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http://dx.doi.org/10.1016/j.autrev.2018.06.010DOI Listing
December 2018

Uveitis in Patients with Multiple Sclerosis in Clinical Trials of Fingolimod: Incidence, Prevalence, and Impact on Disease Course.

Ophthalmology 2019 03 10;126(3):438-444. Epub 2018 Oct 10.

Eye Surgery Associates, East Melbourne, VIC, Australia; Department of Ophthalmology, Alfred Hospital, Melbourne, VIC, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01616420173366
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http://dx.doi.org/10.1016/j.ophtha.2018.10.013DOI Listing
March 2019

Vitamin D for the treatment of multiple sclerosis: a meta-analysis.

J Neurol 2018 Dec 3;265(12):2893-2905. Epub 2018 Oct 3.

School of Medicine, Gold Coast Campus, Griffith University, Gold Coast, QLD, 4222, Australia.

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http://link.springer.com/10.1007/s00415-018-9074-6
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http://dx.doi.org/10.1007/s00415-018-9074-6DOI Listing
December 2018

Validation of a precision tremor measurement system for multiple sclerosis.

J Neurosci Methods 2019 01 19;311:377-384. Epub 2018 Sep 19.

The Bionics Institute, East Melbourne, Australia; Department of Neurology, Royal Melbourne Hospital, Australia; Department of Neuroscience, Central Clinical School, Monash University, Victoria, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S01650270183028
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http://dx.doi.org/10.1016/j.jneumeth.2018.09.022DOI Listing
January 2019

Predictors of relapse and disability progression in MS patients who discontinue disease-modifying therapy.

J Neurol Sci 2018 08 2;391:72-76. Epub 2018 Jun 2.

Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Australia; Department of Neurology, Alfred Hospital, Melbourne, VIC, Australia; Box Hill Hospital, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1016/j.jns.2018.06.001DOI Listing
August 2018

Genotype and Phenotype in Multiple Sclerosis-Potential for Disease Course Prediction?

Curr Treat Options Neurol 2018 Apr 24;20(6):18. Epub 2018 Apr 24.

Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia.

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http://dx.doi.org/10.1007/s11940-018-0505-6DOI Listing
April 2018

Tremor in multiple sclerosis is associated with cerebello-thalamic pathology.

J Neural Transm (Vienna) 2017 12 2;124(12):1509-1514. Epub 2017 Nov 2.

Department of Neurology, The Royal Melbourne Hospital, Level 4 South, 300 Grattan Street, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1007/s00702-017-1798-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686246PMC
December 2017

Cladribine versus fingolimod, natalizumab and interferon β for multiple sclerosis.

Mult Scler 2018 10 31;24(12):1617-1626. Epub 2017 Aug 31.

Department of Neurology, The Royal Melbourne Hospital, Melbourne, VIC, Australia/Department of Medicine, The University of Melbourne, Melbourne, VIC, Australia/Department of Neurology, Box Hill Hospital, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1177/1352458517728812DOI Listing
October 2018

Multimodal characterization of gray matter alterations in neuromyelitis optica.

Mult Scler 2018 09 25;24(10):1308-1316. Epub 2017 Jul 25.

Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, P.R. China/Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, P.R. China.

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http://dx.doi.org/10.1177/1352458517721053DOI Listing
September 2018

Different patterns of longitudinal brain and spinal cord changes and their associations with disability progression in NMO and MS.

Eur Radiol 2018 Jan 30;28(1):96-103. Epub 2017 Jun 30.

Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, People's Republic of China.

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http://dx.doi.org/10.1007/s00330-017-4921-xDOI Listing
January 2018

Timing of high-efficacy therapy in relapsing-remitting multiple sclerosis: A systematic review.

Autoimmun Rev 2017 Jun 17;16(6):658-665. Epub 2017 Apr 17.

Department of Medicine, University of Melbourne, 300 Grattan St, Melbourne 3050, Australia; Department of Neurology, Royal Melbourne Hospital, 300 Grattan St, Melbourne 3050, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2017.04.010DOI Listing
June 2017

Monoclonal antibodies in the treatment of multiple sclerosis: emergence of B-cell-targeted therapies.

Br J Pharmacol 2017 07 26;174(13):1895-1907. Epub 2017 Apr 26.

Multiple Sclerosis Division, The Florey Institute of Neuroscience and Mental Health, Parkville, Vic., Australia.

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http://dx.doi.org/10.1111/bph.13780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466523PMC
July 2017

Gait and balance deterioration over a 12-month period in multiple sclerosis patients with EDSS scores ≤ 3.0.

NeuroRehabilitation 2017 ;40(2):277-284

Department of Anatomy and Neuroscience, The University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.3233/NRE-161413DOI Listing
May 2017

Treatment decisions in multiple sclerosis - insights from real-world observational studies.

Nat Rev Neurol 2017 Feb 13;13(2):105-118. Epub 2017 Jan 13.

Department of Medicine, University of Melbourne, and Department of Neurology, Royal Melbourne Hospital, Grattan Street, Parkville, VIC 3050, Australia.

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http://dx.doi.org/10.1038/nrneurol.2016.188DOI Listing
February 2017

Brain health: time matters in multiple sclerosis.

Mult Scler Relat Disord 2016 Sep 7;9 Suppl 1:S5-S48. Epub 2016 Jul 7.

Department of Neurology, University of Colorado Denver, Aurora, CO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2016.07.003DOI Listing
September 2016

Serial Diffusion Tensor Imaging of the Optic Radiations after Acute Optic Neuritis.

J Ophthalmol 2016 31;2016:2764538. Epub 2016 Jul 31.

Department of Anatomy and Neuroscience, University of Melbourne, Parkville, VIC 3010, Australia; Florey Institute of Neuroscience and Mental Health, Parkville, VIC 3010, Australia; Department of Neurology, Royal Melbourne Hospital, Parkville, VIC 3052, Australia.

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http://dx.doi.org/10.1155/2016/2764538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4983385PMC
August 2016

A genetic basis for multiple sclerosis severity: Red herring or real?

Mol Cell Probes 2016 12 18;30(6):357-365. Epub 2016 Aug 18.

Department of Medicine and Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Australia; Department of Neurology, Royal Melbourne Hospital, Melbourne, Australia; Department of Neurology, Box Hill Hospital, Monash University, Box Hill, Australia.

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http://dx.doi.org/10.1016/j.mcp.2016.08.007DOI Listing
December 2016

Data quality evaluation for observational multiple sclerosis registries.

Mult Scler 2017 Apr 5;23(5):647-655. Epub 2016 Aug 5.

Department of Medicine, University of Melbourne, Melbourne, VIC, Australia/Department of Neurology, Royal Melbourne Hospital, Melbourne, VIC, Australia/Department of Neurology, Box Hill Hospital, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1177/1352458516662728DOI Listing
April 2017

Is my MS patient failing treatment?

Neurology 2016 07 15;87(2):124-5. Epub 2016 Jun 15.

From the Department of Medicine (H.B.), Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Australia; and Johns Hopkins Multiple Sclerosis Center (P.A.C.), Division of Neuroimmunology and Neuroinfectious Diseases, Baltimore, MD.

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http://dx.doi.org/10.1212/WNL.0000000000002851DOI Listing
July 2016

Discontinuing disease-modifying therapy in MS after a prolonged relapse-free period: a propensity score-matched study.

J Neurol Neurosurg Psychiatry 2016 10 13;87(10):1133-7. Epub 2016 Jun 13.

Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria, Australia Department of Medicine (RMH), The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1136/jnnp-2016-313760DOI Listing
October 2016

Observational data: Understanding the real MS world.

Mult Scler 2016 11 6;22(13):1642-1648. Epub 2016 Jun 6.

Department of Medicine, University of Melbourne, Melbourne, VIC, Australia/Department of Neurology, The Royal Melbourne Hospital, Melbourne, VIC, Australia/Box Hill Hospital, Monash University, Box Hill, VIC, Australia.

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http://journals.sagepub.com/doi/10.1177/1352458516653667
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http://dx.doi.org/10.1177/1352458516653667DOI Listing
November 2016

The importance of collecting structured clinical information on multiple sclerosis.

BMC Med 2016 May 31;14:81. Epub 2016 May 31.

Department of Neurology, Royal Melbourne Hospital, Victoria, Australia.

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http://dx.doi.org/10.1186/s12916-016-0627-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888646PMC
May 2016

Comparative efficacy of first-line natalizumab vs IFN-β or glatiramer acetate in relapsing MS.

Neurol Clin Pract 2016 Apr;6(2):102-115

Department of Medicine and Melbourne Brain Centre at the Royal Melbourne Hospital (TS, TK, VJ, HB), University of Melbourne, Australia; Biogen Idec Inc. (AZ, FP, SB, RH), Cambridge, MA; Department of Neurology (HW), University of Münster, Germany; Groene Hart Ziekenhuis (FV), Gouda, the Netherlands; MS Center, Department of Neuroscience, Imaging and Clinical Sciences (AL), University "G. d'Annunzio," Chieti, Italy; MS Center, Department of Neurology, First Medical Faculty (EH, DH), Charles University, Prague, Czech Republic; Center de Réadaptation Déficience Physique Chaudière-Appalache (PG), Levis; Hôpital Notre Dame (PD, AP), Montreal, Canada; Ospedali Riuniti di Salerno (G. Iuliano), Salerno, Italy; 19 Mayis University (M. Terzi), Medical Faculty, Turkey; Hospital Universitario Virgen Macarena (G. Izquierdo), Sevilla, Spain; Orbis Medical Centre (RMMH), Sittard-Geleen, the Netherlands; KTU Medical Faculty Farabi Hospital (CB), Trabzon, Turkey; Neurology Unit (EP, GG), ASUR Marche-AV3, Macerata; Nuovo Ospedale Civile S. Agostino (PS), Modena; AORN San Giuseppe Moscati (DLAS), Avellino, Italy; John Hunter Hospital (JL-S), Newcastle, Australia; Neurological Institute IRCCS Mondino (RB), Pavia, Italy; Neuro Rive-Sud (F. Grand'Maison), Hôpital Charles LeMoyne, Quebec, Canada; University of Parma (F. Granella), Italy; Department of Neurology (LK), University Hospital Basel, Switzerland; Department of Basic Medical Sciences, Neuroscience and Sense Organs (M. Trojano), University of Bari, Italy; and Department of Neurology (HB), Eastern Health, Monash University, Australia.

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http://dx.doi.org/10.1212/CPJ.0000000000000227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4828679PMC
April 2016

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data.

J Vis Exp 2015 Dec 9(106):e53169. Epub 2015 Dec 9.

Department of Neurology, Royal Melbourne Hospital; Department of Medicine (RMH), The University of Melbourne.

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http://dx.doi.org/10.3791/53169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4692792PMC
December 2015

Association of plasma levels of Protein S with disease severity in multiple sclerosis.

Mult Scler J Exp Transl Clin 2015 Jan-Dec;1:2055217315596532. Epub 2015 Jul 24.

Multiple Sclerosis Division, The Florey Institute of Neuroscience and Mental Health, University of Melbourne, Australia.

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http://dx.doi.org/10.1177/2055217315596532DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433335PMC
July 2015