Publications by authors named "Helmut Bergler"

28Publications

From Snapshots to Flipbook-Resolving the Dynamics of Ribosome Biogenesis with Chemical Probes.

Int J Mol Sci 2020 Apr 23;21(8). Epub 2020 Apr 23.

Institute of Molecular Biosciences, University of Graz, Humboldtstraße 50/EG, 8010 Graz, Austria.

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http://dx.doi.org/10.3390/ijms21082998DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215809PMC
April 2020

Shaping the Nascent Ribosome: AAA-ATPases in Eukaryotic Ribosome Biogenesis.

Biomolecules 2019 11 7;9(11). Epub 2019 Nov 7.

Signal Transduction Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, 111 T. W. Alexander Drive, Research Triangle Park, Durham, NC 27709, USA.

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http://dx.doi.org/10.3390/biom9110715DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920918PMC
November 2019

Inhibiting eukaryotic ribosome biogenesis: Mining new tools for basic research and medical applications.

Microb Cell 2019 Aug 20;6(10):491-493. Epub 2019 Aug 20.

Institute of Molecular Biosciences, University of Graz, NAWI Graz, Humboldtstraβe 50-EG, A-8010 Graz, Austria.

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http://dx.doi.org/10.15698/mic2019.10.695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6780010PMC
August 2019

Inhibiting eukaryotic ribosome biogenesis.

BMC Biol 2019 06 10;17(1):46. Epub 2019 Jun 10.

Institute of Molecular Biosciences, University of Graz, Humboldtstrasse 50/EG, A-8010, Graz, Austria.

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http://dx.doi.org/10.1186/s12915-019-0664-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558755PMC
June 2019

Influence of eukaryotic translation initiation factor 6 on non-small cell lung cancer development and progression.

Eur J Cancer 2018 09 1;101:165-180. Epub 2018 Aug 1.

Diagnostic and Research Institute of Pathology, Medical University of Graz, Neue Stiftingtalstrasse 6, 8010 Graz, Austria; Center for Biomarker Research in Medicine, Stiftingtalstrasse 5, 8010 Graz, Austria; Department of Pathology, Medical Faculty, Otto-von-Guericke-University Magdeburg, Leipziger Str. 44, 39120 Magdeburg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049183095
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http://dx.doi.org/10.1016/j.ejca.2018.07.001DOI Listing
September 2018

Viewing pre-60S maturation at a minute's timescale.

Nucleic Acids Res 2018 04;46(6):3140-3151

Institute of Molecular Biosciences, Humboldtstrasse 50/EG, University of Graz, A-8010 Graz, Austria.

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http://dx.doi.org/10.1093/nar/gkx1293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888160PMC
April 2018

Nuclear import of dimerized ribosomal protein Rps3 in complex with its chaperone Yar1.

Sci Rep 2016 11 7;6:36714. Epub 2016 Nov 7.

Institut für Molekulare Biowissenschaften, Universität Graz, Humboldtstrasse 50, 8010 Graz, Austria.

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http://dx.doi.org/10.1038/srep36714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5098186PMC
November 2016

Sequential domain assembly of ribosomal protein S3 drives 40S subunit maturation.

Nat Commun 2016 Feb 2;7:10336. Epub 2016 Feb 2.

Institut für Molekulare Biowissenschaften, Universität Graz, Humboldtstrasse 50, 8010 Graz, Austria.

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http://dx.doi.org/10.1038/ncomms10336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4740875PMC
February 2016

Notch4 Signaling Induces a Mesenchymal-Epithelial-like Transition in Melanoma Cells to Suppress Malignant Behaviors.

Cancer Res 2016 04 22;76(7):1690-7. Epub 2016 Jan 22.

Cancer Biology Unit, Department of Dermatology, Medical University Graz, Graz, Austria. Center for Medical Research (ZMF), Medical University Graz, Graz, Austria. Dermatology Research Centre, The University of Queensland, School of Medicine, Translational Research Institute, Brisbane, Queensland, Australia. Translational Research Institute, University of Queensland Diamantina Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-1722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5167360PMC
April 2016

Ribosomal protein S3 interacts with the NF-κB inhibitor IκBα.

FEBS Lett 2014 Mar 20;588(5):659-64. Epub 2014 Jan 20.

Institut für Molekulare Biowissenschaften, Universität Graz, Humboldtstrasse 50, 8010 Graz, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2013.12.034DOI Listing
March 2014

The drug diazaborine blocks ribosome biogenesis by inhibiting the AAA-ATPase Drg1.

J Biol Chem 2014 Feb 26;289(7):3913-22. Epub 2013 Dec 26.

From the Institut für Molekulare Biowissenschaften, Karl-Franzens-Universität Graz, A-8010 Graz, Austria and.

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http://dx.doi.org/10.1074/jbc.M113.536110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924260PMC
February 2014

Yar1 protects the ribosomal protein Rps3 from aggregation.

J Biol Chem 2012 Jun 8;287(26):21806-15. Epub 2012 May 8.

Institut für Molekulare Biowissenschaften, Universität Graz, Humboldtstrasse 50, A-8010 Graz, Austria.

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http://dx.doi.org/10.1074/jbc.M112.365791DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381143PMC
June 2012

The power of AAA-ATPases on the road of pre-60S ribosome maturation--molecular machines that strip pre-ribosomal particles.

Biochim Biophys Acta 2012 Jan 5;1823(1):92-100. Epub 2011 Jul 5.

University of Fribourg, Department of Biology, Unit of Biochemistry, Chemin du Musée 10, 1700 Fribourg, Switzerland.

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http://dx.doi.org/10.1016/j.bbamcr.2011.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264779PMC
January 2012

Transcriptional activation of ZEB1 by Slug leads to cooperative regulation of the epithelial-mesenchymal transition-like phenotype in melanoma.

J Invest Dermatol 2011 Sep 19;131(9):1877-85. Epub 2011 May 19.

Cancer Biology Unit, Department of Dermatology, Medical University Graz, Graz, Austria.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182526PMC
http://dx.doi.org/10.1038/jid.2011.142DOI Listing
September 2011

The oncoprotein NPM-ALK of anaplastic large-cell lymphoma induces JUNB transcription via ERK1/2 and JunB translation via mTOR signaling.

Blood 2007 Nov 9;110(9):3374-83. Epub 2007 Aug 9.

Klinische Abteilung für Hämatologie, Universitätsklinik für Innere Medizin, Medizinische, Universität Graz, Auenbruggerplatz 38, A-8036 Graz, Austria.

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http://dx.doi.org/10.1182/blood-2007-02-071258DOI Listing
November 2007

Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1.

Mol Cell Biol 2007 Oct 23;27(19):6581-92. Epub 2007 Jul 23.

Institut für Molekulare Biowissenschaften. Karl-Franzens Universität Graz, Universitätsplatz 2, A-8010, Graz, Austria.

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http://dx.doi.org/10.1128/MCB.00668-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2099225PMC
October 2007

Flux of sterol intermediates in a yeast strain deleted of the lanosterol C-14 demethylase Erg11p.

Biochim Biophys Acta 2005 Jul;1735(2):111-8

Institute of Biochemistry, Graz University of Technology, Petersgasse 12/2, A-8010 Graz, Austria.

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http://linkinghub.elsevier.com/retrieve/pii/S138819810500106
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http://dx.doi.org/10.1016/j.bbalip.2005.05.003DOI Listing
July 2005

The transporters Pdr5p and Snq2p mediate diazaborine resistance and are under the control of the gain-of-function allele PDR1-12.

Eur J Biochem 2004 Mar;271(6):1145-52

Institut für Molekularbiologie, Biochemie und Mikrobiologie, Karl-Franzens-Universität Graz, Austria.

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http://dx.doi.org/10.1111/j.1432-1033.2004.04018.xDOI Listing
March 2004

Structural and enzymatic properties of the AAA protein Drg1p from Saccharomyces cerevisiae. Decoupling of intracellular function from ATPase activity and hexamerization.

J Biol Chem 2002 Jul 10;277(30):26788-95. Epub 2002 May 10.

Institut für Molekularbiologie, Biochemie und Mikrobiologie, Karl-Franzens-Universität Graz, Universitätsplatz 2, A-8010 Graz, Austria.

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http://dx.doi.org/10.1074/jbc.M201515200DOI Listing
July 2002