Hellen Kuasne

Alginate-gelatin-Matrigel hydrogels enable the development and multigenerational passaging of patient-derived 3D bioprinted cancer spheroid models.

Authors:

Salvador Flores-Torres Omar Peza Chavez Hellen Kuasne Jose Gil Munguia-Lopez Jacqueline Kort-Mascort Lorenzo Ferri Tao Jiang Charles V Rajadurai Morag Park Veena Sangwan Joseph Matthew Kinsella

Biofabrication 2021 Jan 13. Epub 2021 Jan 13.

Department of Bioengineering, McGill University, McConnell Engineering Building, Room 545, 815 Sherbrooke Street West, Montreal, Quebec, H3A 0G4, CANADA.

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January 2021

Tumour-associated macrophages drive stromal cell-dependent collagen crosslinking and stiffening to promote breast cancer aggression.

Nat Mater 2020 Nov 30. Epub 2020 Nov 30.

UCSF Helen Diller Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA.

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November 2020

GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer.

Nat Commun 2020 08 21;11(1):4205. Epub 2020 Aug 21.

Structural Genomics Consortium, University of Toronto, Toronto, ON, M5G 1L7, Canada.

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August 2020

Chemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors.

Commun Biol 2020 Jun 16;3(1):310. Epub 2020 Jun 16.

Rosalind & Morris Goodman Cancer Research Centre, McGill University, Montréal, QC, H3A 1A3, Canada.

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June 2020

Epigenetic Switch-Induced Viral Mimicry Evasion in Chemotherapy-Resistant Breast Cancer.

Cancer Discov 2020 Sep 16;10(9):1312-1329. Epub 2020 Jun 16.

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

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September 2020

Estrogen-related receptors are targetable ROS sensors.

Authors:

Mathieu Vernier Catherine R Dufour Shawn McGuirk Charlotte Scholtes Xiaojing Li Guillaume Bourmeau Hellen Kuasne Morag Park Julie St-Pierre Etienne Audet-Walsh Vincent Giguère

Genes Dev 2020 04 20;34(7-8):544-559. Epub 2020 Feb 20.

Goodman Cancer Research Centre, McGill University, Montréal, Quebec H3A 1A3, Canada.

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April 2020

E-Cadherin Downregulation is Mediated by Promoter Methylation in Canine Prostate Cancer.

Authors:

Carlos Eduardo Fonseca-Alves Priscila Emiko Kobayashi Antonio Fernando Leis-Filho Patricia de Faria Lainetti Valeria Grieco Hellen Kuasne Silvia Regina Rogatto Renee Laufer-Amorim

Front Genet 2019 29;10:1242. Epub 2019 Nov 29.

Department of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, Sao Paulo State University-UNESP, Botucatu, Brazil.

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November 2019

CD44 Promotes PD-L1 Expression and Its Tumor-Intrinsic Function in Breast and Lung Cancers.

Authors:

Tim Kong Ryuhjin Ahn Kangning Yang Xianbing Zhu Zheng Fu Geneviève Morin Rachel Bramley Nikki C Cliffe Yibo Xue Hellen Kuasne Qinghao Li Sungmi Jung Anne V Gonzalez Sophie Camilleri-Broet Marie-Christine Guiot Morag Park Josie Ursini-Siegel Sidong Huang

Cancer Res 2020 02 13;80(3):444-457. Epub 2019 Nov 13.

Department of Biochemistry, McGill University, Montreal, Quebec, Canada.

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February 2020

DNA Methylation-Based Method to Differentiate Malignant from Benign Thyroid Lesions.

Authors:

Mateus Camargo Barros-Filho Mariana Bisarro Dos Reis Caroline Moraes Beltrami Julia Bette Homem de Mello Fábio Albuquerque Marchi Hellen Kuasne Sandra Aparecida Drigo Victor Piana de Andrade Mauro Ajaj Saieg Clóvis Antonio Lopes Pinto Luiz Paulo Kowalski Silvia Regina Rogatto

Thyroid 2019 09 16;29(9):1244-1254. Epub 2019 Aug 16.

Department of Clinical Genetics, Vejle Hospital, Institute of Regional Health Research, University of Southern Denmark, Vejle, Denmark.

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September 2019

Circulating mRNA signature as a marker for high-risk prostate cancer.

Authors:

Marilesia Ferreira De Souza Hellen Kuasne Mateus De Camargo Barros-Filho Heloísa Lizotti Cilião Fabio Albuquerque Marchi Paulo Emilio Fuganti Silvia Regina Rogatto Ilce Mara De Syllos Cólus

Carcinogenesis 2020 04;41(2):139-145

Department of General Biology, State University of Londrina, Londrina, Paraná, Brazil.

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April 2020

Polysome Profiling of a Human Glioblastoma Reveals Intratumoral Heterogeneity.

Authors:

Fernanda Cristina Sulla Lupinacci Hellen Kuasne Martin Roffé Julia Avian Vassalakis Fernanda Ferreira da Silva Tiago Góss Santos Victor Piana Andrade Paulo Sanematsu Vilma Regina Martins Silvia Regina Rogatto Glaucia Noeli Maroso Hajj

Int J Mol Sci 2019 May 2;20(9). Epub 2019 May 2.

International Research Center, A.C.Camargo Cancer Center, National Institute of Science and Technology in Oncogenomics, São Paulo 01509-010, Brazil.

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May 2019

Loss of DNA methylation is related to increased expression of miR-21 and miR-146b in papillary thyroid carcinoma.

Authors:

Isabella Maria Dias Payão Ortiz Mateus Camargo Barros-Filho Mariana Bisarro Dos Reis Caroline Moraes Beltrami Fabio Albuquerque Marchi Hellen Kuasne Luísa Matos do Canto Julia Bette Homem de Mello Cecilie Abildgaard Clóvis Antônio Lopes Pinto Luiz Paulo Kowalski Silvia Regina Rogatto

Clin Epigenetics 2018 11 20;10(1):144. Epub 2018 Nov 20.

Department of Clinical Genetics, Vejle Hospital, Institute of Regional Health Research, University of Southern Denmark, Beriderbakken 4, 7100, Vejle, Denmark.

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November 2018

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

EMBO J 2018 09 28;37(18). Epub 2018 Aug 28.

Lady Davis Institute for Medical Research, Segal Cancer Centre, Jewish General Hospital, Montreal, QC, Canada

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September 2018

Nuclear loss and cytoplasmic expression of androgen receptor in penile carcinomas: role as a driver event and as a prognosis factor.

Authors:

Hellen Kuasne Mateus C Barros-Filho Fábio A Marchi Sandra A Drigo Cristovam Scapulatempo-Neto Eliney F Faria Silvia R Rogatto

Virchows Arch 2018 Nov 11;473(5):607-614. Epub 2018 Aug 11.

Department of Clinical Genetics, Vejle Hospital, Institute of Regional Health Research, University of Southern Denmark, Beriderbakken 4, 7100, Vejle, Denmark.

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November 2018

Deregulation of E-cadherin, β-catenin, APC and Caveolin-1 expression occurs in canine prostate cancer and metastatic processes.

Authors:

Priscila E Kobayashi Carlos E Fonseca-Alves Luis G Rivera-Calderón Márcio Carvalho Hellen Kuasne Silvia R Rogatto Renée Laufer-Amorim

Res Vet Sci 2018 Jun 5;118:254-261. Epub 2018 Mar 5.

São Paulo State University (UNESP), Department of Veterinary Clinic, School of Veterinary Medicine and Animal Science, Botucatu, SP, Brazil. Electronic address:

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June 2018