Publications by authors named "Helga Westers"

34Publications

Mutational heterogeneity between different regional tumour grades of clear cell renal cell carcinoma.

Exp Mol Pathol 2020 08 4;115:104431. Epub 2020 Apr 4.

Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. Electronic address:

View Article and Find Full Text PDF
August 2020

Comprehensive Profiling of Primary and Metastatic ccRCC Reveals a High Homology of the Metastases to a Subregion of the Primary Tumour.

Cancers (Basel) 2019 Jun 12;11(6). Epub 2019 Jun 12.

Department of Genetics, University of Groningen, University Medical Center Groningen, HPC CB50, 9700 RB Groningen, The Netherlands.

View Article and Find Full Text PDF
June 2019

Functional Studies on Primary Tubular Epithelial Cells Indicate a Tumor Suppressor Role of SETD2 in Clear Cell Renal Cell Carcinoma.

Neoplasia 2016 06 26;18(6):339-46. Epub 2016 May 26.

Department of Genetics, University of Groningen, University Medical Center Groningen, PO Box 30.001, 9700 RB Groningen, the Netherlands. Electronic address:

View Article and Find Full Text PDF
June 2016

SETD2: an epigenetic modifier with tumor suppressor functionality.

Oncotarget 2016 Aug;7(31):50719-50734

Department of Genetics, University of Groningen, University Medical Center Groningen, The Netherlands.

View Article and Find Full Text PDF
August 2016

CoNVaDING: Single Exon Variation Detection in Targeted NGS Data.

Hum Mutat 2016 May 24;37(5):457-64. Epub 2016 Feb 24.

University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands.

View Article and Find Full Text PDF
May 2016

New target genes in endometrial tumors show a role for the estrogen-receptor pathway in microsatellite-unstable cancers.

Hum Mutat 2014 Dec;35(12):1514-23

Department of Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Department of Pathomorphology, Medical College, Jagiellonian University, Krakow, Poland; Institute of Molecular Pathology and Immunology and Medical Faculty, University of Porto, Porto, Portugal.

View Article and Find Full Text PDF
December 2014

Re: Role of the oxidative DNA damage repair gene OGG1 in colorectal tumorigenesis.

J Natl Cancer Inst 2014 Apr 26;106(5). Epub 2014 Apr 26.

Affiliations of authors: Division of Genetics and Epidemiology, Institute of Cancer Research, Sutton, Surrey, UK (BK, RSH); Department of Medicine I, University Hospital Dresden, Dresden, Germany (SB); Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas, Institut d'Investigacions Biomèdiques August Pi i Sunyer, University of Barcelona, Barcelona, Catalonia, Spain (SCB); Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and Medical Research Council (MRC) Human Genetics Unit, Edinburgh, UK (MGD, SMF); German Cancer Research Center, Heidelberg, Germany (AF, KH); Department of Internal Medicine I, Hospital Schleswig-Holstein, Kiel, Germany (JH); Leeds Cancer Research UK Centre, Section of Epidemiology and Biostatistics, Leeds Institute of Cancer Studies and Pathology, St James's University Hospital, Leeds, UK (EN, DTB); Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK (CP, IT); Department of Genetics, Portugese Oncology Institute, Porto, Portugal (MP, MRT); Galician Public Foundation of Genomic Medicine, Centro de Investigación Biomédica en Rad de Enfermedades Rares, Genomics Medicine Group, Hospital Clínico, Santiago de Compostela, University of Santiago de Compostela, Galicia, Spain (CRP); Department of General and Thoraci Surgery, University Hospital Schleswig-Holstein, Kiel, Germany (CS); University of Gronigen, University Medical Centre Gronigen, Department of Genetics, Gronigen, The Netherlands (HW, RMWH); Department of Clinical Genetics, Erasmus Medical Center, Rotterdam, The Netherlands (RMWH); Leiden Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands (TW).

View Article and Find Full Text PDF
April 2014

The MLH1 c.1852_1853delinsGC (p.K618A) variant in colorectal cancer: genetic association study in 18,723 individuals.

PLoS One 2014 17;9(4):e95022. Epub 2014 Apr 17.

Department of Gastroenterology, Hospital Clínic, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona, Barcelona, Catalonia, Spain.

View Article and Find Full Text PDF
December 2014

Functional analysis of the sortase YhcS in Bacillus subtilis.

Proteomics 2011 Oct 31;11(19):3905-13. Epub 2011 Aug 31.

Department of Molecular Genetics, National Institute of Genetic Engineering and Biotechnology, Tehran, Iran.

View Article and Find Full Text PDF
October 2011

Estrogens, MSI and Lynch syndrome-associated tumors.

Biochim Biophys Acta 2009 Dec 25;1796(2):194-200. Epub 2009 Jun 25.

Department of Genetics, University Medical Center Groningen, University of Groningen, PO BOX 30.001, 9700 RB Groningen, The Netherlands.

View Article and Find Full Text PDF
December 2009